MCL coexpression mm9:512
From FANTOM5_SSTAR
Phase1 CAGE Peaks
Short description | |
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Mm9::chr10:33847803..33847820,- | p2@Fam26f |
Mm9::chr13:52692289..52692308,+ | p6@Syk |
Mm9::chr13:52692323..52692334,+ | p11@Syk |
Mm9::chr16:4726284..4726290,+ | p6@Hmox2 |
Mm9::chr17:5195701..5195737,+ | p@chr17:5195701..5195737 + |
Mm9::chr19:41406810..41406843,- | p@chr19:41406810..41406843 - |
Mm9::chr19:41406848..41406866,- | p@chr19:41406848..41406866 - |
Mm9::chr19:41406924..41406948,- | p@chr19:41406924..41406948 - |
Mm9::chr1:34530108..34530141,+ | p@chr1:34530108..34530141 + |
Mm9::chr2:103810335..103810349,+ | p10@Lmo2 |
Mm9::chr4:43467409..43467419,- | p3@Cd72 p3@LOC100504743 |
Mm9::chr5:135083184..135083189,- | p@chr5:135083184..135083189 - |
Mm9::chr9:55937976..55937991,+ | p10@Pstpip1 |
Mm9::chr9:55938017..55938045,+ | p4@Pstpip1 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0005057 | receptor signaling protein activity | 0.0158186854101761 |
GO:0046645 | positive regulation of gamma-delta T cell activation | 0.0158186854101761 |
GO:0045586 | regulation of gamma-delta T cell differentiation | 0.0158186854101761 |
GO:0045588 | positive regulation of gamma-delta T cell differentiation | 0.0158186854101761 |
GO:0046643 | regulation of gamma-delta T cell activation | 0.0158186854101761 |
GO:0043366 | beta selection | 0.0158186854101761 |
GO:0004392 | heme oxygenase (decyclizing) activity | 0.0158186854101761 |
GO:0046629 | gamma-delta T cell activation | 0.0158186854101761 |
GO:0006788 | heme oxidation | 0.0158186854101761 |
GO:0042492 | gamma-delta T cell differentiation | 0.0158186854101761 |
GO:0032632 | interleukin-3 production | 0.0158186854101761 |
GO:0045423 | regulation of granulocyte macrophage colony-stimulating factor biosynthetic process | 0.0158186854101761 |
GO:0042223 | interleukin-3 biosynthetic process | 0.0158186854101761 |
GO:0046638 | positive regulation of alpha-beta T cell differentiation | 0.0158186854101761 |
GO:0045399 | regulation of interleukin-3 biosynthetic process | 0.0158186854101761 |
GO:0032604 | granulocyte macrophage colony-stimulating factor production | 0.0158186854101761 |
GO:0045425 | positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process | 0.0158186854101761 |
GO:0006787 | porphyrin catabolic process | 0.0158186854101761 |
GO:0045401 | positive regulation of interleukin-3 biosynthetic process | 0.0158186854101761 |
GO:0042253 | granulocyte macrophage colony-stimulating factor biosynthetic process | 0.0158186854101761 |
GO:0033015 | tetrapyrrole catabolic process | 0.0158186854101761 |
GO:0043306 | positive regulation of mast cell degranulation | 0.0158186854101761 |
GO:0045647 | negative regulation of erythrocyte differentiation | 0.0158186854101761 |
GO:0046637 | regulation of alpha-beta T cell differentiation | 0.0158186854101761 |
GO:0043304 | regulation of mast cell degranulation | 0.0158186854101761 |
GO:0001820 | serotonin secretion | 0.0158186854101761 |
GO:0005826 | contractile ring | 0.0158186854101761 |
GO:0043302 | positive regulation of leukocyte degranulation | 0.0158186854101761 |
GO:0019903 | protein phosphatase binding | 0.0172993173979733 |
GO:0004716 | receptor signaling protein tyrosine kinase activity | 0.0172993173979733 |
GO:0043300 | regulation of leukocyte degranulation | 0.0172993173979733 |
GO:0045579 | positive regulation of B cell differentiation | 0.0172993173979733 |
GO:0030097 | hemopoiesis | 0.0179514270874 |
GO:0032153 | cell division site | 0.0179514270874 |
GO:0045921 | positive regulation of exocytosis | 0.0179514270874 |
GO:0019815 | B cell receptor complex | 0.0179514270874 |
GO:0032155 | cell division site part | 0.0179514270874 |
GO:0050853 | B cell receptor signaling pathway | 0.0182841233001697 |
GO:0043303 | mast cell degranulation | 0.0182841233001697 |
GO:0002448 | mast cell mediated immunity | 0.0182841233001697 |
GO:0019902 | phosphatase binding | 0.0182841233001697 |
GO:0046641 | positive regulation of alpha-beta T cell proliferation | 0.0182841233001697 |
GO:0048534 | hemopoietic or lymphoid organ development | 0.0182841233001697 |
GO:0005066 | transmembrane receptor protein tyrosine kinase signaling protein activity | 0.0196449609177903 |
GO:0046635 | positive regulation of alpha-beta T cell activation | 0.0196449609177903 |
GO:0002520 | immune system development | 0.0196449609177903 |
GO:0042101 | T cell receptor complex | 0.0199178977336042 |
GO:0046640 | regulation of alpha-beta T cell proliferation | 0.0199178977336042 |
GO:0045577 | regulation of B cell differentiation | 0.0199178977336042 |
GO:0045646 | regulation of erythrocyte differentiation | 0.0199178977336042 |
GO:0043299 | leukocyte degranulation | 0.0212768907620563 |
GO:0007257 | activation of JNK activity | 0.0212768907620563 |
GO:0046634 | regulation of alpha-beta T cell activation | 0.0225346567785881 |
GO:0043507 | positive regulation of JNK activity | 0.0225346567785881 |
GO:0045576 | mast cell activation | 0.023286216360908 |
GO:0045582 | positive regulation of T cell differentiation | 0.023286216360908 |
GO:0046633 | alpha-beta T cell proliferation | 0.023286216360908 |
GO:0050850 | positive regulation of calcium-mediated signaling | 0.0239621154308482 |
GO:0050848 | regulation of calcium-mediated signaling | 0.0239621154308482 |
GO:0019814 | immunoglobulin complex | 0.0239621154308482 |
GO:0045621 | positive regulation of lymphocyte differentiation | 0.026324782844713 |
GO:0043506 | regulation of JNK activity | 0.026324782844713 |
GO:0002444 | myeloid leukocyte mediated immunity | 0.026324782844713 |
GO:0019370 | leukotriene biosynthetic process | 0.0267997444330044 |
GO:0043450 | alkene biosynthetic process | 0.0267997444330044 |
GO:0042168 | heme metabolic process | 0.0267997444330044 |
GO:0045058 | T cell selection | 0.0272329666556482 |
GO:0006691 | leukotriene metabolic process | 0.0272329666556482 |
GO:0045580 | regulation of T cell differentiation | 0.0272329666556482 |
GO:0033013 | tetrapyrrole metabolic process | 0.0272511784361059 |
GO:0006778 | porphyrin metabolic process | 0.0272511784361059 |
GO:0043449 | alkene metabolic process | 0.0272511784361059 |
GO:0017157 | regulation of exocytosis | 0.0272511784361059 |
GO:0001725 | stress fiber | 0.0279942282533293 |
GO:0045638 | negative regulation of myeloid cell differentiation | 0.0279942282533293 |
GO:0032432 | actin filament bundle | 0.0286982855242072 |
GO:0001772 | immunological synapse | 0.0286982855242072 |
GO:0019722 | calcium-mediated signaling | 0.0289992328944968 |
GO:0046632 | alpha-beta T cell differentiation | 0.0289992328944968 |
GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation | 0.0289992328944968 |
GO:0045937 | positive regulation of phosphate metabolic process | 0.0296351105392341 |
GO:0042327 | positive regulation of phosphorylation | 0.0296351105392341 |
GO:0045619 | regulation of lymphocyte differentiation | 0.0306046902405463 |
GO:0046456 | icosanoid biosynthetic process | 0.0315508251837164 |
GO:0000910 | cytokinesis | 0.0323948723522591 |
GO:0050871 | positive regulation of B cell activation | 0.0323948723522591 |
GO:0001934 | positive regulation of protein amino acid phosphorylation | 0.0323948723522591 |
GO:0002274 | myeloid leukocyte activation | 0.0323948723522591 |
GO:0033240 | positive regulation of amine metabolic process | 0.0323948723522591 |
GO:0045764 | positive regulation of amino acid metabolic process | 0.0323948723522591 |
GO:0050851 | antigen receptor-mediated signaling pathway | 0.0323948723522591 |
GO:0042102 | positive regulation of T cell proliferation | 0.0323948723522591 |
GO:0044448 | cell cortex part | 0.0332288983549147 |
GO:0006690 | icosanoid metabolic process | 0.0352139960995021 |
GO:0046631 | alpha-beta T cell activation | 0.0356248379410609 |
GO:0042440 | pigment metabolic process | 0.0356248379410609 |
GO:0002429 | immune response-activating cell surface receptor signaling pathway | 0.0356547788286215 |
GO:0051187 | cofactor catabolic process | 0.0356547788286215 |
GO:0042108 | positive regulation of cytokine biosynthetic process | 0.0356547788286215 |
GO:0046777 | protein amino acid autophosphorylation | 0.0360359566836278 |
GO:0051050 | positive regulation of transport | 0.0360359566836278 |
GO:0050730 | regulation of peptidyl-tyrosine phosphorylation | 0.0360806946379755 |
GO:0002768 | immune response-regulating cell surface receptor signaling pathway | 0.0360806946379755 |
GO:0045637 | regulation of myeloid cell differentiation | 0.0360806946379755 |
GO:0030183 | B cell differentiation | 0.0360806946379755 |
GO:0016540 | protein autoprocessing | 0.0360806946379755 |
GO:0000187 | activation of MAPK activity | 0.0360806946379755 |
GO:0032946 | positive regulation of mononuclear cell proliferation | 0.0360806946379755 |
GO:0002757 | immune response-activating signal transduction | 0.0360806946379755 |
GO:0050671 | positive regulation of lymphocyte proliferation | 0.0360806946379755 |
GO:0030218 | erythrocyte differentiation | 0.0364157538806666 |
GO:0050864 | regulation of B cell activation | 0.0364157538806666 |
GO:0004715 | non-membrane spanning protein tyrosine kinase activity | 0.0367387925569082 |
GO:0002764 | immune response-regulating signal transduction | 0.0367387925569082 |
GO:0045727 | positive regulation of translation | 0.0383256338158725 |
GO:0043406 | positive regulation of MAP kinase activity | 0.0389397889873295 |
GO:0042129 | regulation of T cell proliferation | 0.0391409963062286 |
GO:0031328 | positive regulation of cellular biosynthetic process | 0.0391409963062286 |
GO:0050870 | positive regulation of T cell activation | 0.0391409963062286 |
GO:0007254 | JNK cascade | 0.0391409963062286 |
GO:0019748 | secondary metabolic process | 0.0391409963062286 |
GO:0031098 | stress-activated protein kinase signaling pathway | 0.041511496768158 |
GO:0005938 | cell cortex | 0.0420633321261785 |
GO:0042035 | regulation of cytokine biosynthetic process | 0.0443691239202558 |
GO:0033238 | regulation of amine metabolic process | 0.0448421745003913 |
GO:0001932 | regulation of protein amino acid phosphorylation | 0.0448421745003913 |
GO:0006521 | regulation of amino acid metabolic process | 0.0448421745003913 |
GO:0032944 | regulation of mononuclear cell proliferation | 0.0448421745003913 |
GO:0009891 | positive regulation of biosynthetic process | 0.0448421745003913 |
GO:0050670 | regulation of lymphocyte proliferation | 0.0448421745003913 |
GO:0005886 | plasma membrane | 0.0449410509959089 |
GO:0042098 | T cell proliferation | 0.0449410509959089 |
GO:0042325 | regulation of phosphorylation | 0.0449410509959089 |
GO:0051174 | regulation of phosphorus metabolic process | 0.0449410509959089 |
GO:0019220 | regulation of phosphate metabolic process | 0.0449410509959089 |
GO:0018212 | peptidyl-tyrosine modification | 0.0449410509959089 |
GO:0018108 | peptidyl-tyrosine phosphorylation | 0.0449410509959089 |
GO:0042089 | cytokine biosynthetic process | 0.0471976051634346 |
GO:0043405 | regulation of MAP kinase activity | 0.0471976051634346 |
GO:0042107 | cytokine metabolic process | 0.0471976051634346 |
GO:0051251 | positive regulation of lymphocyte activation | 0.0471976051634346 |
GO:0030217 | T cell differentiation | 0.0471976051634346 |
GO:0050863 | regulation of T cell activation | 0.0483909414071186 |
GO:0045055 | regulated secretory pathway | 0.0484781921249234 |
GO:0002376 | immune system process | 0.0484781921249234 |
GO:0009967 | positive regulation of signal transduction | 0.0488878737328907 |
GO:0046483 | heterocycle metabolic process | 0.0489624807382904 |
GO:0016485 | protein processing | 0.0489624807382904 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
Ontology term | p-value | n |
---|---|---|
common myeloid progenitor | 2.50e-12 | 19 |
hematopoietic cell | 1.62e-09 | 32 |
hematopoietic oligopotent progenitor cell | 1.62e-09 | 32 |
hematopoietic stem cell | 1.62e-09 | 32 |
angioblastic mesenchymal cell | 1.62e-09 | 32 |
hematopoietic multipotent progenitor cell | 1.62e-09 | 32 |
myeloid cell | 1.70e-09 | 16 |
granulocyte monocyte progenitor cell | 8.95e-08 | 7 |
connective tissue cell | 1.18e-07 | 46 |
mesenchymal cell | 1.18e-07 | 46 |
myeloid lineage restricted progenitor cell | 5.44e-07 | 13 |
Ontology term | p-value | n |
---|---|---|
hemolymphoid system | 3.03e-22 | 48 |
immune system | 3.03e-22 | 48 |
hematopoietic system | 5.58e-20 | 45 |
blood island | 5.58e-20 | 45 |
bone marrow | 8.15e-16 | 16 |
bone element | 1.35e-12 | 22 |
skeletal element | 1.35e-12 | 22 |
skeletal system | 1.35e-12 | 22 |
musculoskeletal system | 6.14e-10 | 32 |
lateral plate mesoderm | 1.10e-09 | 87 |
mesoderm | 5.72e-09 | 120 |
mesoderm-derived structure | 5.72e-09 | 120 |
presumptive mesoderm | 5.72e-09 | 120 |
connective tissue | 1.18e-07 | 46 |
hemopoietic organ | 2.47e-07 | 29 |
immune organ | 2.47e-07 | 29 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 0.400158 |
MA0004.1 | 0.258473 |
MA0006.1 | 0.1319 |
MA0007.1 | 0.246385 |
MA0009.1 | 0.649874 |
MA0014.1 | 0.13017 |
MA0017.1 | 0.895796 |
MA0019.1 | 0.480432 |
MA0024.1 | 0.608636 |
MA0025.1 | 0.873493 |
MA0027.1 | 2.275 |
MA0028.1 | 0.430035 |
MA0029.1 | 0.588275 |
MA0030.1 | 0.594419 |
MA0031.1 | 0.561217 |
MA0038.1 | 0.381016 |
MA0040.1 | 0.661716 |
MA0041.1 | 0.198922 |
MA0042.1 | 0.553522 |
MA0043.1 | 0.74191 |
MA0046.1 | 0.683926 |
MA0048.1 | 0.0293065 |
MA0050.1 | 1.43876 |
MA0051.1 | 1.00935 |
MA0052.1 | 0.669354 |
MA0055.1 | 0.45021 |
MA0056.1 | 0 |
MA0057.1 | 0.107353 |
MA0058.1 | 0.541281 |
MA0059.1 | 0.563468 |
MA0060.1 | 0.279564 |
MA0061.1 | 0.0995825 |
MA0063.1 | 0 |
MA0066.1 | 0.371389 |
MA0067.1 | 0.981551 |
MA0068.1 | 0.807617 |
MA0069.1 | 0.669676 |
MA0070.1 | 0.660488 |
MA0071.1 | 0.289658 |
MA0072.1 | 0.652465 |
MA0073.1 | 2.31589 |
MA0074.1 | 0.340281 |
MA0076.1 | 0.163664 |
MA0077.1 | 0.632005 |
MA0078.1 | 0.418168 |
MA0081.1 | 0.605506 |
MA0083.1 | 0.741151 |
MA0084.1 | 1.30392 |
MA0087.1 | 0.699999 |
MA0088.1 | 0.0136969 |
MA0089.1 | 0 |
MA0090.1 | 0.231074 |
MA0091.1 | 0.269175 |
MA0092.1 | 0.231323 |
MA0093.1 | 0.144649 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.879972 |
MA0101.1 | 0.199903 |
MA0103.1 | 0.477056 |
MA0105.1 | 0.0444807 |
MA0106.1 | 0.425111 |
MA0107.1 | 0.153373 |
MA0108.2 | 0.50131 |
MA0109.1 | 0 |
MA0111.1 | 0.242308 |
MA0113.1 | 0.400008 |
MA0114.1 | 0.323836 |
MA0115.1 | 0.744589 |
MA0116.1 | 0.8172 |
MA0117.1 | 0.713754 |
MA0119.1 | 0.200349 |
MA0122.1 | 0.732707 |
MA0124.1 | 0.929684 |
MA0125.1 | 0.857794 |
MA0130.1 | 0 |
MA0131.1 | 0.476296 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 0.77683 |
MA0136.1 | 0.940193 |
MA0139.1 | 0.231431 |
MA0140.1 | 0.330266 |
MA0141.1 | 0.511953 |
MA0142.1 | 0.547747 |
MA0143.1 | 0.414534 |
MA0144.1 | 0.328866 |
MA0145.1 | 0.370377 |
MA0146.1 | 0.903992 |
MA0147.1 | 0.349075 |
MA0148.1 | 0.271704 |
MA0149.1 | 0.204102 |
MA0062.2 | 0.39919 |
MA0035.2 | 0.33429 |
MA0039.2 | 0.317226 |
MA0138.2 | 0.469076 |
MA0002.2 | 0.5079 |
MA0137.2 | 0.169785 |
MA0104.2 | 0.547442 |
MA0047.2 | 0.380343 |
MA0112.2 | 0.918188 |
MA0065.2 | 0.371748 |
MA0150.1 | 0.688872 |
MA0151.1 | 0 |
MA0152.1 | 0.380437 |
MA0153.1 | 0.792819 |
MA0154.1 | 0.283993 |
MA0155.1 | 1.02012 |
MA0156.1 | 0.949678 |
MA0157.1 | 0.518122 |
MA0158.1 | 0 |
MA0159.1 | 0.365914 |
MA0160.1 | 0.274172 |
MA0161.1 | 0 |
MA0162.1 | 0.21028 |
MA0163.1 | 0.493049 |
MA0164.1 | 0.357779 |
MA0080.2 | 1.46165 |
MA0018.2 | 0.366212 |
MA0099.2 | 1.17093 |
MA0079.2 | 0.133151 |
MA0102.2 | 1.35579 |
MA0258.1 | 0.301988 |
MA0259.1 | 0.331447 |
MA0442.1 | 0 |