MCL coexpression mm9:1831
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr6:6812839..6812856,- | p@chr6:6812839..6812856 - |
| Mm9::chr6:6812962..6812979,+ | p1@Dlx6 |
| Mm9::chr6:6812988..6813002,+ | p3@Dlx6 |
| Mm9::chr6:6813269..6813272,+ | p2@Dlx6 |
| Mm9::chr6:6832076..6832092,- | p1@Dlx5 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0030326 | embryonic limb morphogenesis | 0.000258943501150261 |
| GO:0035113 | embryonic appendage morphogenesis | 0.000258943501150261 |
| GO:0035107 | appendage morphogenesis | 0.000258943501150261 |
| GO:0035108 | limb morphogenesis | 0.000258943501150261 |
| GO:0048736 | appendage development | 0.000258943501150261 |
| GO:0060173 | limb development | 0.000258943501150261 |
| GO:0048598 | embryonic morphogenesis | 0.0014479800732008 |
| GO:0005667 | transcription factor complex | 0.00502663040665224 |
| GO:0043565 | sequence-specific DNA binding | 0.00502663040665224 |
| GO:0009790 | embryonic development | 0.00502663040665224 |
| GO:0044451 | nucleoplasm part | 0.0062098763682065 |
| GO:0005654 | nucleoplasm | 0.00625233833473574 |
| GO:0031981 | nuclear lumen | 0.00815663300844468 |
| GO:0031974 | membrane-enclosed lumen | 0.00899439116634181 |
| GO:0043233 | organelle lumen | 0.00899439116634181 |
| GO:0003700 | transcription factor activity | 0.0101738699893271 |
| GO:0044428 | nuclear part | 0.0140269986754033 |
| GO:0009653 | anatomical structure morphogenesis | 0.0172120806986589 |
| GO:0042472 | inner ear morphogenesis | 0.0261206619311803 |
| GO:0042471 | ear morphogenesis | 0.0275672713712403 |
| GO:0043234 | protein complex | 0.0291253627649331 |
| GO:0048839 | inner ear development | 0.0292299925869118 |
| GO:0043583 | ear development | 0.0303461707032352 |
| GO:0006355 | regulation of transcription, DNA-dependent | 0.0303461707032352 |
| GO:0006351 | transcription, DNA-dependent | 0.0303461707032352 |
| GO:0032774 | RNA biosynthetic process | 0.0303461707032352 |
| GO:0003677 | DNA binding | 0.0303461707032352 |
| GO:0045449 | regulation of transcription | 0.0303461707032352 |
| GO:0048856 | anatomical structure development | 0.0303461707032352 |
| GO:0019219 | regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 0.0303461707032352 |
| GO:0006350 | transcription | 0.0303461707032352 |
| GO:0032991 | macromolecular complex | 0.0303461707032352 |
| GO:0010468 | regulation of gene expression | 0.0305772001889394 |
| GO:0031323 | regulation of cellular metabolic process | 0.0321607116515682 |
| GO:0007275 | multicellular organismal development | 0.0326616758899756 |
| GO:0019222 | regulation of metabolic process | 0.0326616758899756 |
| GO:0016070 | RNA metabolic process | 0.0334786777647593 |
| GO:0044446 | intracellular organelle part | 0.0340365919858891 |
| GO:0044422 | organelle part | 0.0340365919858891 |
| GO:0007409 | axonogenesis | 0.0352867503015634 |
| GO:0048667 | neuron morphogenesis during differentiation | 0.0355616341903106 |
| GO:0048812 | neurite morphogenesis | 0.0355616341903106 |
| GO:0000904 | cellular morphogenesis during differentiation | 0.0387104947640834 |
| GO:0007423 | sensory organ development | 0.0387104947640834 |
| GO:0010467 | gene expression | 0.0388094600719565 |
| GO:0031175 | neurite development | 0.0388094600719565 |
| GO:0003676 | nucleic acid binding | 0.0395873215100833 |
| GO:0032502 | developmental process | 0.0407048398569286 |
| GO:0048666 | neuron development | 0.0407048398569286 |
| GO:0006139 | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 0.0432173728216949 |
| GO:0032990 | cell part morphogenesis | 0.0460040440688511 |
| GO:0030030 | cell projection organization and biogenesis | 0.0460040440688511 |
| GO:0048858 | cell projection morphogenesis | 0.0460040440688511 |
| GO:0050794 | regulation of cellular process | 0.0460040440688511 |
| GO:0030182 | neuron differentiation | 0.0460040440688511 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| anterior neural tube | 3.09e-15 | 40 |
| brain grey matter | 3.14e-15 | 29 |
| regional part of telencephalon | 3.14e-15 | 29 |
| telencephalon | 3.14e-15 | 29 |
| regional part of forebrain | 5.24e-15 | 39 |
| forebrain | 5.24e-15 | 39 |
| future forebrain | 5.24e-15 | 39 |
| brain | 1.34e-12 | 47 |
| future brain | 1.34e-12 | 47 |
| pre-chordal neural plate | 8.14e-12 | 49 |
| regional part of brain | 8.51e-12 | 46 |
| gray matter | 1.25e-11 | 34 |
| cerebral cortex | 1.62e-10 | 21 |
| cerebral hemisphere | 1.62e-10 | 21 |
| pallium | 1.62e-10 | 21 |
| regional part of nervous system | 7.73e-10 | 54 |
| neural tube | 3.15e-09 | 52 |
| neural rod | 3.15e-09 | 52 |
| future spinal cord | 3.15e-09 | 52 |
| neural keel | 3.15e-09 | 52 |
| regional part of cerebral cortex | 6.47e-09 | 17 |
| appendage | 4.21e-08 | 12 |
| paired limb/fin | 4.21e-08 | 12 |
| limb | 4.21e-08 | 12 |
| paired limb/fin bud | 4.21e-08 | 12 |
| limb bud | 4.21e-08 | 12 |
| limb/fin field | 4.21e-08 | 12 |
| limb field | 4.21e-08 | 12 |
| appendage girdle complex | 3.30e-07 | 13 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.211284 |
| MA0004.1 | 0.603793 |
| MA0006.1 | 0.419915 |
| MA0007.1 | 0.587678 |
| MA0009.1 | 1.06266 |
| MA0014.1 | 0.418772 |
| MA0017.1 | 0.449113 |
| MA0019.1 | 0.874061 |
| MA0024.1 | 1.01759 |
| MA0025.1 | 1.30092 |
| MA0027.1 | 2.72141 |
| MA0028.1 | 0.43138 |
| MA0029.1 | 0.995171 |
| MA0030.1 | 1.00195 |
| MA0031.1 | 0.965177 |
| MA0038.1 | 0.757669 |
| MA0040.1 | 1.07552 |
| MA0041.1 | 0.522007 |
| MA0042.1 | 0.507715 |
| MA0043.1 | 1.1618 |
| MA0046.1 | 1.09955 |
| MA0048.1 | 0.205696 |
| MA0050.1 | 0.645342 |
| MA0051.1 | 0.767098 |
| MA0052.1 | 1.08379 |
| MA0055.1 | 0.0851423 |
| MA0056.1 | 0 |
| MA0057.1 | 2.39011 |
| MA0058.1 | 0.50032 |
| MA0059.1 | 0.513699 |
| MA0060.1 | 2.4023 |
| MA0061.1 | 0.364227 |
| MA0063.1 | 0 |
| MA0066.1 | 0.746072 |
| MA0067.1 | 1.41352 |
| MA0068.1 | 1.71065 |
| MA0069.1 | 1.08414 |
| MA0070.1 | 1.07418 |
| MA0071.1 | 0.644448 |
| MA0072.1 | 1.06547 |
| MA0073.1 | 0.189951 |
| MA0074.1 | 0.708108 |
| MA0076.1 | 0.470037 |
| MA0077.1 | 1.04318 |
| MA0078.1 | 0.801834 |
| MA0081.1 | 0.53877 |
| MA0083.1 | 1.16099 |
| MA0084.1 | 1.74401 |
| MA0087.1 | 1.11687 |
| MA0088.1 | 0.148348 |
| MA0089.1 | 0 |
| MA0090.1 | 0.566938 |
| MA0091.1 | 0.617887 |
| MA0092.1 | 0.567278 |
| MA0093.1 | 0.440484 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.695835 |
| MA0101.1 | 0.523409 |
| MA0103.1 | 0.460936 |
| MA0105.1 | 0.248108 |
| MA0106.1 | 0.809991 |
| MA0107.1 | 0.454197 |
| MA0108.2 | 0.897859 |
| MA0109.1 | 0 |
| MA0111.1 | 3.55698 |
| MA0113.1 | 0.780358 |
| MA0114.1 | 0.361633 |
| MA0115.1 | 1.16466 |
| MA0116.1 | 0.419688 |
| MA0117.1 | 1.13165 |
| MA0119.1 | 0.524046 |
| MA0122.1 | 1.15196 |
| MA0124.1 | 1.35963 |
| MA0125.1 | 1.28445 |
| MA0130.1 | 0 |
| MA0131.1 | 0.869325 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 1.19898 |
| MA0136.1 | 0.729175 |
| MA0139.1 | 0.295945 |
| MA0140.1 | 0.695713 |
| MA0141.1 | 0.482463 |
| MA0142.1 | 0.950155 |
| MA0143.1 | 0.797553 |
| MA0144.1 | 0.365053 |
| MA0145.1 | 0.476962 |
| MA0146.1 | 0.0604336 |
| MA0147.1 | 0.378658 |
| MA0148.1 | 0.621195 |
| MA0149.1 | 0.529387 |
| MA0062.2 | 0.254018 |
| MA0035.2 | 0.700704 |
| MA0039.2 | 0.0511423 |
| MA0138.2 | 0.861035 |
| MA0002.2 | 0.299191 |
| MA0137.2 | 0.479301 |
| MA0104.2 | 0.315156 |
| MA0047.2 | 0.75686 |
| MA0112.2 | 0.157681 |
| MA0065.2 | 0.477991 |
| MA0150.1 | 0.587557 |
| MA0151.1 | 0 |
| MA0152.1 | 0.756973 |
| MA0153.1 | 1.21594 |
| MA0154.1 | 1.11105 |
| MA0155.1 | 2.24718 |
| MA0156.1 | 0.469089 |
| MA0157.1 | 0.91689 |
| MA0158.1 | 0 |
| MA0159.1 | 0.389847 |
| MA0160.1 | 0.624415 |
| MA0161.1 | 0 |
| MA0162.1 | 0.245828 |
| MA0163.1 | 0.855539 |
| MA0164.1 | 0.729558 |
| MA0080.2 | 0.455167 |
| MA0018.2 | 2.93398 |
| MA0099.2 | 0.854449 |
| MA0079.2 | 3.38617 |
| MA0102.2 | 1.79669 |
| MA0258.1 | 0.346619 |
| MA0259.1 | 0.366802 |
| MA0442.1 | 0 |
