Coexpression cluster:C77

Full id: C77_Saos2_osteosarcoma_Neutrophils_Natural_Chondrocyte_Basophils_CD8

Phase1 CAGE Peaks

Hg19::chr10:54411290..54411295,-	p@chr10:54411290..54411295 -
Hg19::chr11:124478164..124478168,-	p@chr11:124478164..124478168 -
Hg19::chr11:124479851..124479862,-	p@chr11:124479851..124479862 -
Hg19::chr11:124480065..124480072,-	p@chr11:124480065..124480072 -
Hg19::chr11:124480073..124480086,-	p@chr11:124480073..124480086 -
Hg19::chr11:124481316..124481334,+	p1@PANX3
Hg19::chr11:124481361..124481366,+	p2@PANX3
Hg19::chr11:124489771..124489792,+	p@chr11:124489771..124489792 +
Hg19::chr11:126573090..126573097,+	p@chr11:126573090..126573097 +
Hg19::chr11:126573105..126573118,+	p@chr11:126573105..126573118 +
Hg19::chr11:131213225..131213274,+	p@chr11:131213225..131213274 +
Hg19::chr11:299519..299533,-	p1@IFITM5
Hg19::chr11:30911556..30911574,+	p@chr11:30911556..30911574 +
Hg19::chr11:46326686..46326700,+	p@chr11:46326686..46326700 +
Hg19::chr11:81619863..81619881,+	p@chr11:81619863..81619881 +
Hg19::chr11:85416537..85416545,-	p22@SYTL2
Hg19::chr11:85416548..85416560,-	p18@SYTL2
Hg19::chr11:92613787..92613796,+	p@chr11:92613787..92613796 +
Hg19::chr11:92613813..92613863,+	p@chr11:92613813..92613863 +
Hg19::chr11:93129900..93129911,+	p@chr11:93129900..93129911 +
Hg19::chr12:49366362..49366379,-	p@chr12:49366362..49366379 -
Hg19::chr12:49366390..49366401,-	p@chr12:49366390..49366401 -
Hg19::chr12:49366435..49366452,-	p@chr12:49366435..49366452 -
Hg19::chr12:53721918..53721923,-	p@chr12:53721918..53721923 -
Hg19::chr12:53730147..53730177,-	p2@SP7
Hg19::chr12:53730178..53730189,-	p3@SP7
Hg19::chr12:67914694..67914707,+	p@chr12:67914694..67914707 +
Hg19::chr13:42264610..42264621,-	p@chr13:42264610..42264621 -
Hg19::chr13:42264908..42264914,-	p@chr13:42264908..42264914 -
Hg19::chr13:42267088..42267096,-	p@chr13:42267088..42267096 -
Hg19::chr13:42269057..42269068,-	p3@AK130122
Hg19::chr13:42269075..42269089,-	p1@AK130122
Hg19::chr13:42269101..42269110,-	p4@AK130122
Hg19::chr13:42269136..42269148,-	p2@AK130122
Hg19::chr14:28314513..28314526,-	p1@ENST00000555797
Hg19::chr15:30360639..30360648,-	p@chr15:30360639..30360648 -
Hg19::chr15:30360803..30360815,-	p@chr15:30360803..30360815 -
Hg19::chr16:53706815..53706819,-	p@chr16:53706815..53706819 -
Hg19::chr16:53707116..53707125,-	p@chr16:53707116..53707125 -
Hg19::chr16:57147279..57147287,+	p3@AF542551 p3@BC010627
Hg19::chr16:70731167..70731181,-	p@chr16:70731167..70731181 -
Hg19::chr16:70731292..70731335,-	p@chr16:70731292..70731335 -
Hg19::chr17:1932231..1932269,+	p@chr17:1932231..1932269 +
Hg19::chr17:4705621..4705645,-	p@chr17:4705621..4705645 -
Hg19::chr17:79965744..79965750,+	p11@ASPSCR1
Hg19::chr17:79965883..79965891,+	p@chr17:79965883..79965891 +
Hg19::chr17:79965892..79965924,+	p@chr17:79965892..79965924 +
Hg19::chr17:79965930..79965938,+	p@chr17:79965930..79965938 +
Hg19::chr17:79965942..79965947,+	p@chr17:79965942..79965947 +
Hg19::chr17:79966486..79966493,+	p@chr17:79966486..79966493 +
Hg19::chr17:79966585..79966594,+	p@chr17:79966585..79966594 +
Hg19::chr17:79966610..79966637,+	p@chr17:79966610..79966637 +
Hg19::chr17:79966642..79966666,+	p@chr17:79966642..79966666 +
Hg19::chr17:79966939..79966954,+	p@chr17:79966939..79966954 +
Hg19::chr17:79967254..79967267,+	p@chr17:79967254..79967267 +
Hg19::chr17:79968448..79968454,+	p@chr17:79968448..79968454 +
Hg19::chr17:79968458..79968470,+	p@chr17:79968458..79968470 +
Hg19::chr17:79968480..79968490,+	p@chr17:79968480..79968490 +
Hg19::chr17:79968522..79968530,+	p@chr17:79968522..79968530 +
Hg19::chr17:79968630..79968635,+	p@chr17:79968630..79968635 +
Hg19::chr17:79968655..79968672,+	p@chr17:79968655..79968672 +
Hg19::chr17:79969860..79969871,+	p@chr17:79969860..79969871 +
Hg19::chr18:66061928..66061937,-	p@chr18:66061928..66061937 -
Hg19::chr18:66061970..66061982,-	p@chr18:66061970..66061982 -
Hg19::chr19:28145289..28145296,-	p@chr19:28145289..28145296 -
Hg19::chr19:28163893..28163904,+	p@chr19:28163893..28163904 +
Hg19::chr19:28164112..28164118,+	p@chr19:28164112..28164118 +
Hg19::chr19:28185172..28185189,-	p@chr19:28185172..28185189 -
Hg19::chr19:28198009..28198037,-	p@chr19:28198009..28198037 -
Hg19::chr19:28198123..28198149,+	p@chr19:28198123..28198149 +
Hg19::chr19:28198179..28198195,+	p@chr19:28198179..28198195 +
Hg19::chr19:28198206..28198222,+	p@chr19:28198206..28198222 +
Hg19::chr19:28202503..28202508,-	p@chr19:28202503..28202508 -
Hg19::chr19:28202519..28202528,-	p@chr19:28202519..28202528 -
Hg19::chr19:28236792..28236797,+	p@chr19:28236792..28236797 +
Hg19::chr19:28237057..28237073,+	p@chr19:28237057..28237073 +
Hg19::chr19:28242224..28242230,+	p@chr19:28242224..28242230 +
Hg19::chr19:28248054..28248062,+	p@chr19:28248054..28248062 +
Hg19::chr19:28260754..28260759,+	p@chr19:28260754..28260759 +
Hg19::chr19:28262882..28262886,+	p@chr19:28262882..28262886 +
Hg19::chr19:28269266..28269269,+	p@chr19:28269266..28269269 +
Hg19::chr19:28271083..28271089,+	p@chr19:28271083..28271089 +
Hg19::chr19:28271937..28271942,+	p@chr19:28271937..28271942 +
Hg19::chr19:28272010..28272016,+	p@chr19:28272010..28272016 +
Hg19::chr19:3314450..3314461,+	p@chr19:3314450..3314461 +
Hg19::chr19:45821290..45821301,-	p@chr19:45821290..45821301 -
Hg19::chr19:45821324..45821328,-	p@chr19:45821324..45821328 -
Hg19::chr1:105493789..105493826,-	p@chr1:105493789..105493826 -
Hg19::chr1:112316957..112316974,+	p@chr1:112316957..112316974 +
Hg19::chr1:16343894..16343914,-	p@chr1:16343894..16343914 -
Hg19::chr1:16343915..16343936,-	p@chr1:16343915..16343936 -
Hg19::chr1:16343937..16343946,-	p@chr1:16343937..16343946 -
Hg19::chr1:199050050..199050059,-	p@chr1:199050050..199050059 -
Hg19::chr1:199050926..199050944,-	p@chr1:199050926..199050944 -
Hg19::chr1:21835908..21835926,+	p1@ALPL
Hg19::chr1:21880493..21880518,+	p4@ALPL
Hg19::chr1:21880519..21880528,+	p11@ALPL
Hg19::chr1:21890586..21890595,+	p9@ALPL
Hg19::chr1:21894015..21894027,+	p@chr1:21894015..21894027 +
Hg19::chr1:21894055..21894060,+	p@chr1:21894055..21894060 +
Hg19::chr1:21904551..21904569,-	p@chr1:21904551..21904569 -
Hg19::chr1:21912937..21912944,+	p2@ENST00000457706
Hg19::chr1:21912975..21912983,+	p1@ENST00000457706
Hg19::chr1:25291275..25291301,-	p12@RUNX3
Hg19::chr1:39992756..39992784,-	p@chr1:39992756..39992784 -
Hg19::chr1:41868813..41868817,-	p@chr1:41868813..41868817 -
Hg19::chr1:52116793..52116805,+	p@chr1:52116793..52116805 +
Hg19::chr1:62392583..62392613,+	p@chr1:62392583..62392613 +
Hg19::chr1:62392630..62392651,+	p@chr1:62392630..62392651 +
Hg19::chr1:77864109..77864116,+	p@chr1:77864109..77864116 +
Hg19::chr20:17519265..17519274,-	p@chr20:17519265..17519274 -
Hg19::chr20:17519297..17519304,-	p@chr20:17519297..17519304 -
Hg19::chr20:4444563..4444585,+	p@chr20:4444563..4444585 +
Hg19::chr20:4444611..4444628,+	p@chr20:4444611..4444628 +
Hg19::chr20:4451158..4451164,-	p@chr20:4451158..4451164 -
Hg19::chr20:58676515..58676524,+	p@chr20:58676515..58676524 +
Hg19::chr20:58676530..58676545,+	p@chr20:58676530..58676545 +
Hg19::chr2:121684363..121684405,+	p@chr2:121684363..121684405 +
Hg19::chr2:128896491..128896497,+	p@chr2:128896491..128896497 +
Hg19::chr2:128896543..128896553,+	p@chr2:128896543..128896553 +
Hg19::chr2:190240072..190240096,+	p@chr2:190240072..190240096 +
Hg19::chr2:190240113..190240131,+	p@chr2:190240113..190240131 +
Hg19::chr2:190240185..190240190,+	p@chr2:190240185..190240190 +
Hg19::chr2:190245902..190245918,-	p@chr2:190245902..190245918 -
Hg19::chr2:200470609..200470616,-	p@chr2:200470609..200470616 -
Hg19::chr2:200677330..200677348,+	p@chr2:200677330..200677348 +
Hg19::chr2:37593641..37593648,+	p@chr2:37593641..37593648 +
Hg19::chr2:37593656..37593667,+	p@chr2:37593656..37593667 +
Hg19::chr2:38466754..38466766,-	p2@ENST00000450854
Hg19::chr2:38466814..38466823,-	p8@ENST00000450854
Hg19::chr2:54252811..54252825,-	p@chr2:54252811..54252825 -
Hg19::chr2:71791188..71791195,+	p@chr2:71791188..71791195 +
Hg19::chr2:8960249..8960254,-	p@chr2:8960249..8960254 -
Hg19::chr3:141678730..141678768,-	p@chr3:141678730..141678768 -
Hg19::chr3:149824497..149824506,-	p@chr3:149824497..149824506 -
Hg19::chr3:149824547..149824554,-	p@chr3:149824547..149824554 -
Hg19::chr3:180588303..180588310,-	p1@CCDC39
Hg19::chr3:41723047..41723059,-	p5@ULK4
Hg19::chr3:55016696..55016715,-	p@chr3:55016696..55016715 -
Hg19::chr3:55016721..55016732,-	p@chr3:55016721..55016732 -
Hg19::chr3:58021410..58021424,+	p@chr3:58021410..58021424 +
Hg19::chr4:123392011..123392012,+	p@chr4:123392011..123392012 +
Hg19::chr4:145430542..145430557,-	p@chr4:145430542..145430557 -
Hg19::chr4:15964182..15964193,+	p2@CU693033
Hg19::chr4:15964231..15964260,+	p1@CU693033
Hg19::chr4:15964293..15964341,+	p4@CU693033
Hg19::chr4:15964788..15964805,-	p1@FGFBP2
Hg19::chr4:15964806..15964817,-	p3@FGFBP2
Hg19::chr4:15964830..15964851,-	p2@FGFBP2
Hg19::chr4:16020432..16020477,-	p@chr4:16020432..16020477 -
Hg19::chr4:16020500..16020547,-	p@chr4:16020500..16020547 -
Hg19::chr4:16027038..16027047,-	p@chr4:16027038..16027047 -
Hg19::chr4:188536760..188536764,-	p@chr4:188536760..188536764 -
Hg19::chr4:188536783..188536788,-	p@chr4:188536783..188536788 -
Hg19::chr4:188536806..188536817,-	p@chr4:188536806..188536817 -
Hg19::chr4:188536873..188536891,-	p@chr4:188536873..188536891 -
Hg19::chr4:189321717..189321731,+	p2@ENST00000512839 p2@ENST00000513313 p2@uc003izo.1
Hg19::chr4:189321732..189321736,+	p7@ENST00000512839 p7@ENST00000513313 p7@uc003izo.1
Hg19::chr4:189321921..189321935,+	p4@ENST00000512839 p4@ENST00000513313 p4@uc003izo.1
Hg19::chr4:189321956..189321963,+	p6@ENST00000512839 p6@ENST00000513313 p6@uc003izo.1
Hg19::chr4:35027177..35027183,-	p@chr4:35027177..35027183 -
Hg19::chr4:41614752..41614765,+	p27@LIMCH1
Hg19::chr4:57931672..57931693,-	p4@ENST00000512512
Hg19::chr4:66535152..66535180,+	p3@LOC100144602
Hg19::chr4:77506733..77506743,+	p@chr4:77506733..77506743 +
Hg19::chr4:88653561..88653570,-	p1@ENST00000506480
Hg19::chr4:88654323..88654347,-	p@chr4:88654323..88654347 -
Hg19::chr4:88666648..88666655,-	p@chr4:88666648..88666655 -
Hg19::chr4:88720698..88720722,+	p1@IBSP
Hg19::chr4:88723803..88723839,+	p@chr4:88723803..88723839 +
Hg19::chr4:88727274..88727278,+	p@chr4:88727274..88727278 +
Hg19::chr4:88731810..88731821,+	p@chr4:88731810..88731821 +
Hg19::chr4:88731854..88731869,+	p@chr4:88731854..88731869 +
Hg19::chr4:88731871..88731877,+	p@chr4:88731871..88731877 +
Hg19::chr4:88731888..88731889,+	p@chr4:88731888..88731889 +
Hg19::chr4:88732513..88732528,+	p@chr4:88732513..88732528 +
Hg19::chr4:88732806..88732816,+	p@chr4:88732806..88732816 +
Hg19::chr5:82307578..82307601,-	p@chr5:82307578..82307601 -
Hg19::chr5:86679358..86679365,+	p@chr5:86679358..86679365 +
Hg19::chr6:113772872..113772888,-	p@chr6:113772872..113772888 -
Hg19::chr6:116447293..116447325,-	p1@COL10A1
Hg19::chr6:143447228..143447237,+	p16@AIG1
Hg19::chr6:143447268..143447286,+	p4@AIG1
Hg19::chr6:143447290..143447299,+	p17@AIG1
Hg19::chr6:143447300..143447316,+	p8@AIG1
Hg19::chr6:143447322..143447336,+	p11@AIG1
Hg19::chr6:155427848..155427862,+	p@chr6:155427848..155427862 +
Hg19::chr6:161454830..161454839,+	p@chr6:161454830..161454839 +
Hg19::chr6:23228832..23228835,+	p@chr6:23228832..23228835 +
Hg19::chr6:23228836..23228864,+	p@chr6:23228836..23228864 +
Hg19::chr6:41613840..41613845,+	p18@MDFI
Hg19::chr6:45295874..45295877,+	p47@RUNX2
Hg19::chr6:45322890..45322895,+	p@chr6:45322890..45322895 +
Hg19::chr6:45382521..45382525,+	p@chr6:45382521..45382525 +
Hg19::chr6:81430111..81430117,+	p@chr6:81430111..81430117 +
Hg19::chr6:81435467..81435479,+	p@chr6:81435467..81435479 +
Hg19::chr7:131582395..131582410,+	p1@ENST00000452219
Hg19::chr7:131583321..131583328,-	p@chr7:131583321..131583328 -
Hg19::chr7:25370183..25370193,+	p@chr7:25370183..25370193 +
Hg19::chr7:48078148..48078160,-	p@chr7:48078148..48078160 -
Hg19::chr7:78161666..78161675,-	p@chr7:78161666..78161675 -
Hg19::chr7:80000207..80000217,+	p@chr7:80000207..80000217 +
Hg19::chr8:104215580..104215589,-	p1@ENST00000523915
Hg19::chr8:134020867..134020882,-	p@chr8:134020867..134020882 -
Hg19::chr8:134020899..134020917,-	p@chr8:134020899..134020917 -
Hg19::chr8:134021151..134021176,-	p@chr8:134021151..134021176 -
Hg19::chr8:134021602..134021610,+	p@chr8:134021602..134021610 +
Hg19::chr8:134029743..134029754,+	p34@TG
Hg19::chr8:134029937..134029944,+	p22@TG
Hg19::chr8:134104319..134104347,-	p@chr8:134104319..134104347 -
Hg19::chr8:134128500..134128506,+	p@chr8:134128500..134128506 +
Hg19::chr8:60090206..60090207,+	p@chr8:60090206..60090207 +
Hg19::chr8:64349734..64349746,+	p@chr8:64349734..64349746 +
Hg19::chr8:72504214..72504256,-	p1@ENST00000518177
Hg19::chr8:97570368..97570378,+	p@chr8:97570368..97570378 +
Hg19::chr9:118246509..118246532,+	p@chr9:118246509..118246532 +
Hg19::chr9:29940198..29940204,+	p@chr9:29940198..29940204 +
Hg19::chr9:29941904..29941908,+	p@chr9:29941904..29941908 +
Hg19::chr9:29942046..29942058,+	p@chr9:29942046..29942058 +
Hg19::chr9:29942099..29942136,+	p@chr9:29942099..29942136 +
Hg19::chr9:29942164..29942166,+	p@chr9:29942164..29942166 +
Hg19::chr9:29963867..29963872,+	p@chr9:29963867..29963872 +
Hg19::chr9:72436290..72436302,-	p@chr9:72436290..72436302 -
Hg19::chr9:72436304..72436310,-	p@chr9:72436304..72436310 -
Hg19::chr9:72436332..72436343,-	p@chr9:72436332..72436343 -
Hg19::chr9:97952157..97952178,-	p1@AF086119
Hg19::chr9:97968566..97968576,-	p@chr9:97968566..97968576 -
Hg19::chrX:57619083..57619113,+	p1@ZXDB
Hg19::chrX:57930371..57930380,-	p@chrX:57930371..57930380 -
Hg19::chrX:57933412..57933415,-	p@chrX:57933412..57933415 -
Hg19::chrX:57934585..57934628,-	p@chrX:57934585..57934628 -
Hg19::chrX:57936237..57936264,-	p1@ZXDA
Hg19::chrX:58052946..58052954,+	p@chrX:58052946..58052954 +
Hg19::chrX:58168137..58168144,-	p@chrX:58168137..58168144 -
Hg19::chrX:58169111..58169120,-	p@chrX:58169111..58169120 -
Hg19::chrX:58230080..58230084,-	p@chrX:58230080..58230084 -
Hg19::chrX:82002721..82002725,-	p@chrX:82002721..82002725 -
Hg19::chrX:95277870..95277872,+	p@chrX:95277870..95277872 +

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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p.value	FDR	nGenes	nPathway	Name
1.1538319656142e-07	7.3037563423379e-05	4	65	Endochondral Ossification (Wikipathways):WP474

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0001501	skeletal development	1.38622787099341e-05
GO:0001503	ossification	1.38622787099341e-05
GO:0031214	biomineral formation	1.38622787099341e-05
GO:0046849	bone remodeling	1.47690842449678e-05
GO:0048771	tissue remodeling	1.69478882821983e-05
GO:0009888	tissue development	0.000973078205899421
GO:0001649	osteoblast differentiation	0.00331469258547911
GO:0048513	organ development	0.0109287657732847
GO:0007275	multicellular organismal development	0.0350956604091168
GO:0032502	developmental process	0.0372980257525899
GO:0048731	system development	0.0372980257525899
GO:0004035	alkaline phosphatase activity	0.0489916179153388

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

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Cell Type

Ontology term	p-value	n
CD8-positive, alpha-beta T cell	1.04e-07	11

Uber Anatomy

Ontology term	p-value	n
adult organism	4.21e-24	115
central nervous system	3.01e-11	82
regional part of nervous system	6.14e-10	94
nervous system	6.14e-10	94
brain	2.52e-08	69
future brain	2.52e-08	69
neural tube	1.05e-07	57
neural rod	1.05e-07	57
future spinal cord	1.05e-07	57
neural keel	1.05e-07	57
regional part of brain	3.17e-07	59
tissue	4.96e-07	787
blood	8.12e-07	15
haemolymphatic fluid	8.12e-07	15
organism substance	8.12e-07	15

Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
{{{tfbs_overrepresentation_jaspar}}}

ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

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No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

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