FFCP PHASE1:Hg19::chr13:24133122..24133144,-: Difference between revisions
From FANTOM5_SSTAR
No edit summary |
|||
(5 intermediate revisions by the same user not shown) | |||
Line 1: | Line 1: | ||
{{FFCP | {{FFCP | ||
|DHSsupport=supported | |||
|DPIdataset=robust | |||
|EntrezGene=NA | |EntrezGene=NA | ||
|GencodeV16b_All_Build2_RSEM10_CPAT_consensus=no_gencodeV16_or_build2_transcript | |||
|HGNC=NA | |HGNC=NA | ||
|TSSclassifier=strong | |||
|UniProt=NA | |UniProt=NA | ||
|association_with_transcript=NA | |association_with_transcript=NA | ||
|cluster_id=chr13:24133122..24133144,- | |||
|description=CAGE_peak_at_chr13:24133122..24133144,- | |description=CAGE_peak_at_chr13:24133122..24133144,- | ||
|id=chr13:24133122..24133144,- | |id=chr13:24133122..24133144,- | ||
|ontology_enrichment_celltype=CL:0000057!4.90e-07!75 | |ontology_enrichment_celltype=CL:0000057!4.90e-07!75 | ||
|ontology_enrichment_celltype_v019=CL:0000148;1.66e-12;10!CL:0000147;1.03e-08;14!CL:0002367;4.37e-08;2!CL:0000047;2.29e-07;2 | |||
|ontology_enrichment_celltype_v019_2=CL:0000148,1.61e-12,10;CL:0000541,1.61e-12,10;CL:0000147,1.01e-08,14;CL:0002367,4.24e-08,2 | |||
|ontology_enrichment_development_v019=UBERON:0005062;3.28e-08;4!UBERON:0007284;3.28e-08;4 | |||
|ontology_enrichment_disease= | |ontology_enrichment_disease= | ||
|ontology_enrichment_disease_v019=DOID:1909;2.97e-08;2 | |||
|ontology_enrichment_disease_v019_2=DOID:1909,3.09e-08,2 | |||
|ontology_enrichment_uberon=UBERON:0000062!2.08e-11!511;UBERON:0003102!1.02e-07!95;UBERON:0004121!2.98e-07!169;UBERON:0000475!4.72e-07!365 | |ontology_enrichment_uberon=UBERON:0000062!2.08e-11!511;UBERON:0003102!1.02e-07!95;UBERON:0004121!2.98e-07!169;UBERON:0000475!4.72e-07!365 | ||
|ontology_enrichment_uberon_v019=UBERON:0003296;4.02e-14;4!UBERON:0010133;4.02e-14;4!UBERON:0003978;8.19e-11;3!UBERON:0000946;8.19e-11;3!UBERON:0007100;1.77e-09;25!UBERON:0001905;4.37e-08;2!UBERON:0002757;4.37e-08;2!UBERON:0010134;4.37e-08;2!UBERON:0005408;4.37e-08;2!UBERON:0005969;4.37e-08;2!UBERON:0001899;4.37e-08;2!UBERON:0003956;4.37e-08;2!UBERON:0001894;4.46e-08;7!UBERON:0002133;5.76e-08;2!UBERON:0000007;1.01e-07;2!UBERON:0003127;2.29e-07;2 | |||
|ontology_enrichment_uberon_v019_2=UBERON:0003296,2.09e-14,4;UBERON:0010133,2.09e-14,4;UBERON:0003978,6.74e-11,3;UBERON:0009751,6.74e-11,3;UBERON:0000946,6.74e-11,3;UBERON:0002523,6.74e-11,3;UBERON:0005983,6.74e-11,3;UBERON:0002165,6.74e-11,3;UBERON:0002062,6.74e-11,3;UBERON:0007280,6.74e-11,3;UBERON:0007100,1.11e-10,27;UBERON:0001894,3.11e-08,7;UBERON:0006222,3.11e-08,7;UBERON:0005969,4.24e-08,2;UBERON:0003956,4.24e-08,2;UBERON:0001905,4.54e-08,2;UBERON:0002757,4.54e-08,2;UBERON:0010134,4.54e-08,2;UBERON:0005408,4.54e-08,2;UBERON:0001899,4.54e-08,2;UBERON:0000007,5.04e-08,2;UBERON:0002133,7.88e-08,2;UBERON:0000948,1.07e-07,24;UBERON:0005498,1.07e-07,24;UBERON:0004140,1.07e-07,24;UBERON:0009881,1.07e-07,24;UBERON:0004141,1.07e-07,24;UBERON:0003084,1.07e-07,24;UBERON:0007005,1.07e-07,24;UBERON:0004139,1.07e-07,24;UBERON:0004291,1.07e-07,24;UBERON:0003127,1.18e-07,2 | |||
|phase1_expression=0.54503513781167,0.642301571672949,0.281908808191942,2.00146596706261,0.893922188854576,0,0,0,0,0.491467873003018,0,0,0,0.37129905888014,0.331397375727916,0,0,0,0,0,0,0,0.286235987131057,0.136874425072884,0,0,0,0,0,0,0,0,0,0.369754010166788,0,0,0,0,0,0,0,0,0,0,0.377875943688809,0,0.232429036905685,1.23350366406548,0.619412741790207,0,0.256160706529101,0.236482229888585,0.344745680736619,0,0,0.188242339542605,0.272906150057846,0.449446968890169,0,0.962787081228281,0,0,0,0,0.290209238628584,1.13477044938228,0,0,1.0429658368404,0.217188844705117,0.605399502633369,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,2.43806866313962,2.68280343881454,0,0,0,0.144846518960824,1.5905718941022,2.43317435151318,0.0945348171640679,0,0,0,0,0,1.62273696827342,0.870648686496336,0.797747763113191,0,0,0,0.198762407366705,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.436094052142534,0,0,0.397227542439656,0,0,0,1.06748995729705,0,0.622422070799533,0.134710672069688,0.163461903113459,0,0.576175924479999,1.17160715916898,0,0,0.149448680551801,0.23486899728753,0,0.140450806702248,1.22492502752936,0.61417158655884,0.619954687054593,0,0.741800787835671,0,0,0,0.125118519871964,0.277064115484183,0,0,0.45071417671979,0.113432183160021,0.358779271377724,0.427114777637135,1.69545520927649,0.600182192168805,0.206105058476878,1.03056216018252,0.37223371266318,0.843881661206331,0.487185025805993,0.252433774244115,0.276149695926898,0.161646056818812,2.13005755509969,0.403008392910561,0,0,0,0.286804595389004,0,0,0,0,0.252320850875628,0,0,0.643240938192885,0,0,0,0.118306800039844,0,0,0,0,0,0,0,0,0,0,0.4115740113314,0,0,0,0,0,0,0.171567810298526,0.329250856225877,1.1240175325762,0.402115889646523,0.0925884451585296,0.325808305310325,0,0,0,0.117408694235822,0,0,0,0,0,0,0.468008530278475,0,0,0,0,0.179117045405697,0.290633938513962,0,0.985326475791887,0,0,0,0,5.27032522625003,4.58386110669933,1.17217447210047,0,9.04881935789247,6.9078903304101,2.5724378936752,0.672786506072164,0,0.22001485746285,0,0,0,0.26593811658487,0,0.514414748524284,0,0.532844358032199,0.142977993658148,0,0.823240336780769,0,0,0,0,0,0,0,0,0,0,0,0,0,0.410952645100767,0,0,0,0,0,1.01637849688985,1.30139853857622,0,0,0,0,0,0,0.24538298343828,0,0,0,0.178428988797162,0.315404830067869,0.585707074963566,0,0,0,0,0,0.173767228936166,0.587403472388222,1.02943027143257,0,0,0,0,0,0,0,1.2276957863045,0,0.256278298511402,0,0,0,0.154209693802656,0,0.164254312027618,0,0,0,0,0.0920809889358963,0.114814448164607,0.728364672026868,0.393373244878272,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.103041011647722,0,0,0.574265537996172,0,0,0,0.154048617114644,0,0.137836572484531,0.107420244868274,0.435050081742686,0,0,0.165284915360978,0.192190067365106,0,0.10115778085555,0,0.31481234683064,0,0,0,0,0,0,0.744316738719335,0.316379424718726,0.38126038784765,0,0,0,0,0,0,0,0,0,0,0,0,0,0.136499911407986,0,1.13008116620243,0,0,0,0.578775534266688,0.655894752046633,0,0,0,0.143411352204052,0,0,0.354761064070598,0.211107635297664,0.329294892959902,2.27683904259429,2.44954304171488,0.0962221127255121,0,0,0.188287601553558,0.43050537267123,0,0.443430153536676,0.229723400206959,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0711418433484141,0,0,0,0,0,0,0,0.783399478865116,0,0,0,0,0,0,0,0,0,0.781552381608161,0,0,0,0,0,0,0.146508179271894,0,0,1.13654458722565,0,0,0,0,0.140669416410513,0.111308705022906,0,0,0.19924798825107,0,0,0.511343412510774,0,0,0.0898683511473268,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.885741385813839,0.120596438625408,0,0.110579259931225,0,0,0.32681539055697,0,0,0,0,0,0,0,0.274792780205587,0,0,0,0.166211681900156,0,0,0,0,0,0,0,0,0,0,0.0884575645033392,0,0,0,0,0.067401132980677,0,0.234264445725339,0,0.19566461893209,0,0,0,0,0.063186579628488,0,0.103688191397247,0,0.330991955875499,0,0,0,0,0,0,0,0,0,0.387025325156341,0.803982487948041,0.246346371159628,0.0969890164884194,0,0,0.959293472527256,0,0.126621591911757,0.195551382734803,0.0801588202515337,0.213452994739353,0.19980960958213,0.144090417154106,0.229073192331831,0,1.1524383839052,0.248505071130865,0.471388069233591,0,0,1.01998217636322,0,0,0.410716136675979,0,0,0,1.11712960508902,1.83328339209347,7.17873024576814,0.399358000997982,6.00916467391199,2.23171457441873,1.88113722962834,0,0,1.6544468284517,1.483485450861,2.15691340333392,0,0,0,0.136203406111576,0,0,0,0.2249738915515,0,0.0607495566580247,0,0,0,0,1.97216073266129,0,0,0,0,0,0,0,0,0,0,0,0,0,1.42211251997706,0.66116300871345,0,0,0.106787412567695,8.33182817028229,0.828478110694391,0,0,0,0,0,0,0,0,0,0,0.244052529803926,0.625954653532499,0,1.22021956690538,0.18628920882415,0,1.49976489554528,2.42638588066636,4.28198000317451,0,0,0,0,0.701139929541673,0.554805861502613,0.189403005275089,0.754703705257725,0.889811221596536,0,0,0.310874401165561,0.443565449968902,0.318593534327405,0,0.621051827505038,0,0,0,0.150257608997218,0,0,0,0.214821114084977,0,0.398095888698616,0,0,0,0,0,0,0.260994291965212,0,0,0,1.07453304648892,0,0,0.530067437837643,0,0,0.256241518587947,0,0.303859956177382,0,0,0,0,0.327609848846413,0,0.211312123358627,0,0.426766918776564,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.319267718114302,0,0,0.0691572524642179,0,0,0.0981477185010256,0.825788063434183,0,0,0,0.690359926060101,0,0,0.20170506870352,0.781514011233092,0,0.49131575253029,0.147856086217045,0,0,0.206686796501184,0.0634158101939068,0,0.548257766857182,0,0,0,2.67850917939143,2.01770233331294,1.82089681270989,2.95960848756687,0,0,0.171488009437418,0.135939465953663,0,0,0.333694205676207,0,0.314231179832004,0,0,0,0.47775168788705,0.285906176706625,0,0,0,0,0.207216164163037,0,0,3.01159151174194,0.118332000730565,0.0852134047591577,0,0,0,0,0,3.14080747568778,0.121917924982269,0,0.102662806856247,0,0.485710993059139,0.467878926924211,0,0,0,0,0.452888530700021,0,0,0,0,0.235676547101626,0.785233868459781,3.56455680392503,0,0.169927114687817,0,0,0,0,0.352894871715692,0,0,5.50475140085449,0.143339583151451,0.157771562193185,0,0,0,0.371995018166751,1.38652688589425,0,0.126166424835079,0,0,0,0,0,0,0,0.267964130156178,0,0.310298987585686,1.0661699095049,0.23806443146374,0,0.0620747142958579,0.448527450322454,0,0,0.217716747896961,0,0,1.5061663132462,1.66330178273007,0.162806537221949,0,0,0,0,0,0,0.665756774185513,0,0 | |phase1_expression=0.54503513781167,0.642301571672949,0.281908808191942,2.00146596706261,0.893922188854576,0,0,0,0,0.491467873003018,0,0,0,0.37129905888014,0.331397375727916,0,0,0,0,0,0,0,0.286235987131057,0.136874425072884,0,0,0,0,0,0,0,0,0,0.369754010166788,0,0,0,0,0,0,0,0,0,0,0.377875943688809,0,0.232429036905685,1.23350366406548,0.619412741790207,0,0.256160706529101,0.236482229888585,0.344745680736619,0,0,0.188242339542605,0.272906150057846,0.449446968890169,0,0.962787081228281,0,0,0,0,0.290209238628584,1.13477044938228,0,0,1.0429658368404,0.217188844705117,0.605399502633369,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,2.43806866313962,2.68280343881454,0,0,0,0.144846518960824,1.5905718941022,2.43317435151318,0.0945348171640679,0,0,0,0,0,1.62273696827342,0.870648686496336,0.797747763113191,0,0,0,0.198762407366705,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.436094052142534,0,0,0.397227542439656,0,0,0,1.06748995729705,0,0.622422070799533,0.134710672069688,0.163461903113459,0,0.576175924479999,1.17160715916898,0,0,0.149448680551801,0.23486899728753,0,0.140450806702248,1.22492502752936,0.61417158655884,0.619954687054593,0,0.741800787835671,0,0,0,0.125118519871964,0.277064115484183,0,0,0.45071417671979,0.113432183160021,0.358779271377724,0.427114777637135,1.69545520927649,0.600182192168805,0.206105058476878,1.03056216018252,0.37223371266318,0.843881661206331,0.487185025805993,0.252433774244115,0.276149695926898,0.161646056818812,2.13005755509969,0.403008392910561,0,0,0,0.286804595389004,0,0,0,0,0.252320850875628,0,0,0.643240938192885,0,0,0,0.118306800039844,0,0,0,0,0,0,0,0,0,0,0.4115740113314,0,0,0,0,0,0,0.171567810298526,0.329250856225877,1.1240175325762,0.402115889646523,0.0925884451585296,0.325808305310325,0,0,0,0.117408694235822,0,0,0,0,0,0,0.468008530278475,0,0,0,0,0.179117045405697,0.290633938513962,0,0.985326475791887,0,0,0,0,5.27032522625003,4.58386110669933,1.17217447210047,0,9.04881935789247,6.9078903304101,2.5724378936752,0.672786506072164,0,0.22001485746285,0,0,0,0.26593811658487,0,0.514414748524284,0,0.532844358032199,0.142977993658148,0,0.823240336780769,0,0,0,0,0,0,0,0,0,0,0,0,0,0.410952645100767,0,0,0,0,0,1.01637849688985,1.30139853857622,0,0,0,0,0,0,0.24538298343828,0,0,0,0.178428988797162,0.315404830067869,0.585707074963566,0,0,0,0,0,0.173767228936166,0.587403472388222,1.02943027143257,0,0,0,0,0,0,0,1.2276957863045,0,0.256278298511402,0,0,0,0.154209693802656,0,0.164254312027618,0,0,0,0,0.0920809889358963,0.114814448164607,0.728364672026868,0.393373244878272,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.103041011647722,0,0,0.574265537996172,0,0,0,0.154048617114644,0,0.137836572484531,0.107420244868274,0.435050081742686,0,0,0.165284915360978,0.192190067365106,0,0.10115778085555,0,0.31481234683064,0,0,0,0,0,0,0.744316738719335,0.316379424718726,0.38126038784765,0,0,0,0,0,0,0,0,0,0,0,0,0,0.136499911407986,0,1.13008116620243,0,0,0,0.578775534266688,0.655894752046633,0,0,0,0.143411352204052,0,0,0.354761064070598,0.211107635297664,0.329294892959902,2.27683904259429,2.44954304171488,0.0962221127255121,0,0,0.188287601553558,0.43050537267123,0,0.443430153536676,0.229723400206959,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0711418433484141,0,0,0,0,0,0,0,0.783399478865116,0,0,0,0,0,0,0,0,0,0.781552381608161,0,0,0,0,0,0,0.146508179271894,0,0,1.13654458722565,0,0,0,0,0.140669416410513,0.111308705022906,0,0,0.19924798825107,0,0,0.511343412510774,0,0,0.0898683511473268,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.885741385813839,0.120596438625408,0,0.110579259931225,0,0,0.32681539055697,0,0,0,0,0,0,0,0.274792780205587,0,0,0,0.166211681900156,0,0,0,0,0,0,0,0,0,0,0.0884575645033392,0,0,0,0,0.067401132980677,0,0.234264445725339,0,0.19566461893209,0,0,0,0,0.063186579628488,0,0.103688191397247,0,0.330991955875499,0,0,0,0,0,0,0,0,0,0.387025325156341,0.803982487948041,0.246346371159628,0.0969890164884194,0,0,0.959293472527256,0,0.126621591911757,0.195551382734803,0.0801588202515337,0.213452994739353,0.19980960958213,0.144090417154106,0.229073192331831,0,1.1524383839052,0.248505071130865,0.471388069233591,0,0,1.01998217636322,0,0,0.410716136675979,0,0,0,1.11712960508902,1.83328339209347,7.17873024576814,0.399358000997982,6.00916467391199,2.23171457441873,1.88113722962834,0,0,1.6544468284517,1.483485450861,2.15691340333392,0,0,0,0.136203406111576,0,0,0,0.2249738915515,0,0.0607495566580247,0,0,0,0,1.97216073266129,0,0,0,0,0,0,0,0,0,0,0,0,0,1.42211251997706,0.66116300871345,0,0,0.106787412567695,8.33182817028229,0.828478110694391,0,0,0,0,0,0,0,0,0,0,0.244052529803926,0.625954653532499,0,1.22021956690538,0.18628920882415,0,1.49976489554528,2.42638588066636,4.28198000317451,0,0,0,0,0.701139929541673,0.554805861502613,0.189403005275089,0.754703705257725,0.889811221596536,0,0,0.310874401165561,0.443565449968902,0.318593534327405,0,0.621051827505038,0,0,0,0.150257608997218,0,0,0,0.214821114084977,0,0.398095888698616,0,0,0,0,0,0,0.260994291965212,0,0,0,1.07453304648892,0,0,0.530067437837643,0,0,0.256241518587947,0,0.303859956177382,0,0,0,0,0.327609848846413,0,0.211312123358627,0,0.426766918776564,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.319267718114302,0,0,0.0691572524642179,0,0,0.0981477185010256,0.825788063434183,0,0,0,0.690359926060101,0,0,0.20170506870352,0.781514011233092,0,0.49131575253029,0.147856086217045,0,0,0.206686796501184,0.0634158101939068,0,0.548257766857182,0,0,0,2.67850917939143,2.01770233331294,1.82089681270989,2.95960848756687,0,0,0.171488009437418,0.135939465953663,0,0,0.333694205676207,0,0.314231179832004,0,0,0,0.47775168788705,0.285906176706625,0,0,0,0,0.207216164163037,0,0,3.01159151174194,0.118332000730565,0.0852134047591577,0,0,0,0,0,3.14080747568778,0.121917924982269,0,0.102662806856247,0,0.485710993059139,0.467878926924211,0,0,0,0,0.452888530700021,0,0,0,0,0.235676547101626,0.785233868459781,3.56455680392503,0,0.169927114687817,0,0,0,0,0.352894871715692,0,0,5.50475140085449,0.143339583151451,0.157771562193185,0,0,0,0.371995018166751,1.38652688589425,0,0.126166424835079,0,0,0,0,0,0,0,0.267964130156178,0,0.310298987585686,1.0661699095049,0.23806443146374,0,0.0620747142958579,0.448527450322454,0,0,0.217716747896961,0,0,1.5061663132462,1.66330178273007,0.162806537221949,0,0,0,0,0,0,0.665756774185513,0,0 | ||
|short_description=p@chr13:24133122..24133144,- | |short_description=p@chr13:24133122..24133144,- | ||
}} | }} |
Latest revision as of 15:08, 24 July 2015
Short description: | p@chr13:24133122..24133144, - |
---|---|
Species: | Human (Homo sapiens) |
DPI dataset: | Robust |
TSS-like-by-RIKEN-classifier(Yes/No): | Yes |
DHS support(Yes/No): | Yes |
Description: | CAGE_peak_at_chr13:24133122..24133144, - |
Coexpression cluster: | NA |
Association with transcript: | NA |
EntrezGene: | NA |
HGNC: | NA |
UniProt: | NA |
Genome view: | ZENBU |
View on UCSC genome browser
CAGE Expression
- Click each plot point to find sample in table
Ontology-based sample term enrichment analysis<b>Summary:</b>This analysis has been performed by utilizing wilcoxon rank sum test.When the number of associated cells/tissues are > n , randomly sampled n cells/tissues are used for P value calculation with rank sum test. this process are repeated several times, and the P values are averaged on the log space <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source dataset<br>data
Ontology term | p-value | n |
---|---|---|
melanocyte | 1.61e-12 | 10 |
melanoblast | 1.61e-12 | 10 |
pigment cell | 1.01e-08 | 14 |
trabecular meshwork cell | 4.24e-08 | 2 |
Ontology term | p-value | n |
---|---|---|
gland of diencephalon | 2.09e-14 | 4 |
neuroendocrine gland | 2.09e-14 | 4 |
valve | 6.74e-11 | 3 |
cardiac mesenchyme | 6.74e-11 | 3 |
cardial valve | 6.74e-11 | 3 |
tunica intima | 6.74e-11 | 3 |
heart layer | 6.74e-11 | 3 |
endocardium | 6.74e-11 | 3 |
endocardial cushion | 6.74e-11 | 3 |
presumptive endocardium | 6.74e-11 | 3 |
primary circulatory organ | 1.11e-10 | 27 |
diencephalon | 3.11e-08 | 7 |
future diencephalon | 3.11e-08 | 7 |
reticulum trabeculare | 4.24e-08 | 2 |
aqueous drainage system | 4.24e-08 | 2 |
pineal body | 4.54e-08 | 2 |
regional part of epithalamus | 4.54e-08 | 2 |
secretory circumventricular organ | 4.54e-08 | 2 |
circumventricular organ | 4.54e-08 | 2 |
epithalamus | 4.54e-08 | 2 |
pituitary gland | 5.04e-08 | 2 |
atrioventricular valve | 7.88e-08 | 2 |
heart | 1.07e-07 | 24 |
primitive heart tube | 1.07e-07 | 24 |
primary heart field | 1.07e-07 | 24 |
anterior lateral plate mesoderm | 1.07e-07 | 24 |
heart tube | 1.07e-07 | 24 |
heart primordium | 1.07e-07 | 24 |
cardiac mesoderm | 1.07e-07 | 24 |
cardiogenic plate | 1.07e-07 | 24 |
heart rudiment | 1.07e-07 | 24 |
open tracheal system trachea | 1.18e-07 | 2 |
Ontology term | p-value | n |
---|---|---|
melanoma | 3.09e-08 | 2 |