FF:12760-136B6: Difference between revisions
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{{f5samples | {{f5samples | ||
|ancestors_in_anatomy_facet=UBERON: | |DRA_sample_Accession=CAGE@SAMD00004881 | ||
|ancestors_in_cell_lineage_facet=CL:0000000 | |DRA_sample_Accession_RNASeq=sRNA-Seq@SAMD00004881 | ||
|accession_numbers=CAGE;DRX008601;DRR009473;DRZ000898;DRZ002283;DRZ012248;DRZ013633 | |||
|accession_numbers_RNASeq=sRNA-Seq;DRX037313;DRR041679;DRZ007321 | |||
|ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0001474,UBERON:0002384,UBERON:0000479,UBERON:0000062,UBERON:0000061,UBERON:0000465,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0004765,UBERON:0002204,UBERON:0001434 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000055,CL:0000003,CL:0000548,CL:0002320,CL:0002371,CL:0000255,CL:0000062 | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0000350,FF:0000344,FF:0000332,FF:0100971,FF:0100385,FF:0100407,FF:0000593 | |||
|comment=A2 T0 | |comment=A2 T0 | ||
|created_by= | |created_by= | ||
|creation_date= | |creation_date= | ||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |def= | ||
|donor= | |||
|fonse_cell_line=FF:0100385 | |fonse_cell_line=FF:0100385 | ||
|fonse_cell_line_closure=FF:0100385 | |fonse_cell_line_closure=FF:0100385 | ||
| Line 35: | Line 44: | ||
|fonse_treatment_closure=EFO:0000369,FF:0000332,FF:0000593,FF:12760-136B6 | |fonse_treatment_closure=EFO:0000369,FF:0000332,FF:0000593,FF:12760-136B6 | ||
|has_quality= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.timecourse.hCAGE/Saos-2%2520osteosarcoma%2520treated%2520with%2520ascorbic%2520acid%2520and%2520BGP%2520to%2520induce%2520calcification%252c%252000hr00min%252c%2520biol_rep2%2520%2528A2%2520T0%2529.CNhs12859.12760-136B6.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.timecourse.hCAGE/Saos-2%2520osteosarcoma%2520treated%2520with%2520ascorbic%2520acid%2520and%2520BGP%2520to%2520induce%2520calcification%252c%252000hr00min%252c%2520biol_rep2%2520%2528A2%2520T0%2529.CNhs12859.12760-136B6.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.timecourse.hCAGE/Saos-2%2520osteosarcoma%2520treated%2520with%2520ascorbic%2520acid%2520and%2520BGP%2520to%2520induce%2520calcification%252c%252000hr00min%252c%2520biol_rep2%2520%2528A2%2520T0%2529.CNhs12859.12760-136B6.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.timecourse.hCAGE/Saos-2%2520osteosarcoma%2520treated%2520with%2520ascorbic%2520acid%2520and%2520BGP%2520to%2520induce%2520calcification%252c%252000hr00min%252c%2520biol_rep2%2520%2528A2%2520T0%2529.CNhs12859.12760-136B6.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.timecourse.hCAGE/Saos-2%2520osteosarcoma%2520treated%2520with%2520ascorbic%2520acid%2520and%2520BGP%2520to%2520induce%2520calcification%252c%252000hr00min%252c%2520biol_rep2%2520%2528A2%2520T0%2529.CNhs12859.12760-136B6.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:12760-136B6 | |id=FF:12760-136B6 | ||
|is_a=EFO:0002091;;FF: | |is_a=EFO:0002091;;FF:0000593 | ||
|name=Saos-2 osteosarcoma treated with ascorbic acid and BGP to induce calcification | |is_obsolete= | ||
|library_id=CNhs12859 | |||
|library_id_phase_based=2:CNhs12859 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;12760 | |||
|microRNAs_nonnovel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer/#/human#srna;sample;SRhi10065.GTGGCC.12760 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;12760 | |||
|microRNAs_novel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer_novel/#/human#srna;sample;SRhi10065.GTGGCC.12760 | |||
|name=Saos-2 osteosarcoma treated with ascorbic acid and BGP to induce calcification | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |profile_cagescan=,,, | ||
|profile_hcage=CNhs12859,LSID973,release012,COMPLETED | |profile_hcage=CNhs12859,LSID973,release012,COMPLETED | ||
|profile_rnaseq= | |profile_rnaseq= | ||
|profile_srnaseq=,,, | |profile_srnaseq=,,, | ||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
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|rna_box=136 | |rna_box=136 | ||
|rna_catalog_number= | |rna_catalog_number= | ||
| Line 56: | Line 82: | ||
|rna_tube_id=136B6 | |rna_tube_id=136B6 | ||
|rna_weight_ug=10.87 | |rna_weight_ug=10.87 | ||
|rnaseq_library_id=SRhi10065.GTGGCC | |||
|sample_age= | |sample_age= | ||
|sample_category=time courses | |||
|sample_cell_catalog= | |sample_cell_catalog= | ||
|sample_cell_line=Saos-2 | |sample_cell_line=Saos-2 | ||
| Line 69: | Line 97: | ||
|sample_ethnicity= | |sample_ethnicity= | ||
|sample_experimental_condition=Saos-2 osteosarcoma treated with ascorbic acid and BGP to induce calcification | |sample_experimental_condition=Saos-2 osteosarcoma treated with ascorbic acid and BGP to induce calcification | ||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;3.28694854971549e-289!GO:0043226;organelle;4.55799438036546e-247!GO:0043229;intracellular organelle;1.51910849448168e-246!GO:0043231;intracellular membrane-bound organelle;1.540327395663e-243!GO:0043227;membrane-bound organelle;1.540327395663e-243!GO:0005737;cytoplasm;5.97455140668863e-169!GO:0044422;organelle part;2.02082234488925e-166!GO:0044446;intracellular organelle part;9.2919371132238e-165!GO:0005634;nucleus;3.18514691800628e-130!GO:0032991;macromolecular complex;2.43051316862708e-116!GO:0044444;cytoplasmic part;2.53376665628659e-111!GO:0044238;primary metabolic process;5.77511957358522e-110!GO:0044237;cellular metabolic process;8.47586104293998e-108!GO:0043170;macromolecule metabolic process;1.14222502357186e-106!GO:0044428;nuclear part;1.48948710950534e-92!GO:0030529;ribonucleoprotein complex;1.4934947369715e-88!GO:0043233;organelle lumen;4.46312781104785e-82!GO:0031974;membrane-enclosed lumen;4.46312781104785e-82!GO:0005515;protein binding;1.52915125167532e-79!GO:0003723;RNA binding;1.74147471337705e-79!GO:0043283;biopolymer metabolic process;4.65607516866328e-77!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.60848852208944e-70!GO:0010467;gene expression;8.65529582359981e-65!GO:0016043;cellular component organization and biogenesis;3.59886917512644e-62!GO:0043234;protein complex;2.00853304322572e-61!GO:0005739;mitochondrion;1.76139743535489e-60!GO:0006396;RNA processing;2.7742703581868e-57!GO:0031981;nuclear lumen;6.27610248792197e-55!GO:0005840;ribosome;1.70604964936301e-49!GO:0003676;nucleic acid binding;5.04149021080839e-49!GO:0031090;organelle membrane;3.62808577933967e-47!GO:0043228;non-membrane-bound organelle;8.8203711621096e-47!GO:0043232;intracellular non-membrane-bound organelle;8.8203711621096e-47!GO:0006412;translation;1.43631643636517e-46!GO:0006259;DNA metabolic process;3.63203434367302e-46!GO:0016071;mRNA metabolic process;4.50099320316619e-45!GO:0006996;organelle organization and biogenesis;1.33576330682121e-44!GO:0031967;organelle envelope;1.61865512841243e-43!GO:0044429;mitochondrial part;2.01959798629044e-43!GO:0031975;envelope;3.15299395919372e-43!GO:0003735;structural constituent of ribosome;5.60960820193793e-43!GO:0019538;protein metabolic process;1.30341333093444e-41!GO:0033036;macromolecule localization;3.45365358937381e-41!GO:0008380;RNA splicing;3.49873318457093e-41!GO:0015031;protein transport;1.8251850511993e-40!GO:0046907;intracellular transport;8.11827030727768e-40!GO:0006397;mRNA processing;3.65080145917402e-39!GO:0007049;cell cycle;9.85133074277446e-39!GO:0016070;RNA metabolic process;2.90285952062406e-37!GO:0044260;cellular macromolecule metabolic process;5.93627817593588e-37!GO:0008104;protein localization;9.48423761769523e-37!GO:0065003;macromolecular complex assembly;1.51009753520195e-36!GO:0005654;nucleoplasm;2.38156150220733e-36!GO:0044267;cellular protein metabolic process;5.22172150098194e-36!GO:0033279;ribosomal subunit;1.11706240480883e-35!GO:0045184;establishment of protein localization;1.23947734380328e-35!GO:0044249;cellular biosynthetic process;7.34952866050993e-35!GO:0009058;biosynthetic process;2.70955478161496e-34!GO:0009059;macromolecule biosynthetic process;1.38923558985738e-33!GO:0005829;cytosol;5.51285386636798e-32!GO:0022613;ribonucleoprotein complex biogenesis and assembly;6.79202743665389e-32!GO:0022607;cellular component assembly;7.77941342917352e-32!GO:0000166;nucleotide binding;4.39703138834241e-31!GO:0006886;intracellular protein transport;5.14151712064538e-31!GO:0005694;chromosome;1.86009596917789e-29!GO:0044451;nucleoplasm part;3.05927900586139e-29!GO:0005681;spliceosome;3.32749162896498e-29!GO:0005740;mitochondrial envelope;1.24527532968341e-28!GO:0022402;cell cycle process;4.18282068168511e-28!GO:0031966;mitochondrial membrane;1.64223729799826e-27!GO:0000278;mitotic cell cycle;3.07440743144052e-27!GO:0019866;organelle inner membrane;8.6849185992983e-27!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.71090104089194e-26!GO:0051649;establishment of cellular localization;6.32521126008145e-26!GO:0044427;chromosomal part;1.57167435082967e-25!GO:0051641;cellular localization;1.71975444865858e-25!GO:0006974;response to DNA damage stimulus;3.21234722040044e-25!GO:0005743;mitochondrial inner membrane;4.28450806677266e-24!GO:0051276;chromosome organization and biogenesis;1.57280653716184e-23!GO:0016462;pyrophosphatase activity;1.86790223782093e-23!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.96489670396804e-23!GO:0016817;hydrolase activity, acting on acid anhydrides;2.68672807150096e-23!GO:0022403;cell cycle phase;8.58659534832165e-23!GO:0017111;nucleoside-triphosphatase activity;1.06772424459817e-22!GO:0032553;ribonucleotide binding;1.93170224840816e-22!GO:0032555;purine ribonucleotide binding;1.93170224840816e-22!GO:0006512;ubiquitin cycle;3.71325323538782e-22!GO:0006281;DNA repair;3.77379818814485e-22!GO:0000087;M phase of mitotic cell cycle;1.15941847500156e-21!GO:0007067;mitosis;1.88733444099507e-21!GO:0051301;cell division;2.6521076986977e-21!GO:0017076;purine nucleotide binding;4.62160170451529e-21!GO:0006119;oxidative phosphorylation;9.30675484978087e-21!GO:0044445;cytosolic part;1.26001299469652e-20!GO:0016874;ligase activity;1.39539439241131e-20!GO:0044455;mitochondrial membrane part;2.77844527694538e-20!GO:0005524;ATP binding;7.43169924718948e-20!GO:0051603;proteolysis involved in cellular protein catabolic process;7.59009691122394e-20!GO:0032559;adenyl ribonucleotide binding;1.24213618981377e-19!GO:0019941;modification-dependent protein catabolic process;1.42632331335903e-19!GO:0043632;modification-dependent macromolecule catabolic process;1.42632331335903e-19!GO:0044257;cellular protein catabolic process;3.37065557828667e-19!GO:0012505;endomembrane system;3.42360788180526e-19!GO:0006511;ubiquitin-dependent protein catabolic process;3.42431227980293e-19!GO:0006260;DNA replication;4.14526633076943e-19!GO:0000279;M phase;7.56897136998941e-19!GO:0044265;cellular macromolecule catabolic process;8.91351197690225e-19!GO:0015935;small ribosomal subunit;1.1647638952784e-18!GO:0006325;establishment and/or maintenance of chromatin architecture;2.27614952073356e-18!GO:0022618;protein-RNA complex assembly;3.43807216747644e-18!GO:0015934;large ribosomal subunit;3.5936179037724e-18!GO:0030554;adenyl nucleotide binding;4.8932890897999e-18!GO:0005730;nucleolus;5.5903262032497e-18!GO:0006323;DNA packaging;1.15691738787962e-17!GO:0031980;mitochondrial lumen;1.26680592981436e-17!GO:0005759;mitochondrial matrix;1.26680592981436e-17!GO:0043285;biopolymer catabolic process;1.68230441959073e-17!GO:0006457;protein folding;4.02544886960225e-17!GO:0008134;transcription factor binding;5.12983405927795e-17!GO:0006605;protein targeting;1.28136025814414e-16!GO:0031965;nuclear membrane;1.65778663635559e-16!GO:0000502;proteasome complex (sensu Eukaryota);2.14806259145997e-16!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;2.45743128496523e-16!GO:0005746;mitochondrial respiratory chain;3.14221497500521e-16!GO:0008135;translation factor activity, nucleic acid binding;3.22378945208601e-16!GO:0009719;response to endogenous stimulus;3.31949423115792e-16!GO:0048770;pigment granule;6.77536468935606e-16!GO:0042470;melanosome;6.77536468935606e-16!GO:0000398;nuclear mRNA splicing, via spliceosome;9.02243364053677e-16!GO:0000375;RNA splicing, via transesterification reactions;9.02243364053677e-16!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;9.02243364053677e-16!GO:0005635;nuclear envelope;1.69652650487683e-15!GO:0009057;macromolecule catabolic process;1.72457172840029e-15!GO:0030163;protein catabolic process;1.94087149387666e-15!GO:0050136;NADH dehydrogenase (quinone) activity;2.75100667744017e-15!GO:0003954;NADH dehydrogenase activity;2.75100667744017e-15!GO:0008137;NADH dehydrogenase (ubiquinone) activity;2.75100667744017e-15!GO:0043412;biopolymer modification;8.93174860047254e-15!GO:0042254;ribosome biogenesis and assembly;1.20779909300506e-14!GO:0016604;nuclear body;1.39584263476954e-14!GO:0044453;nuclear membrane part;1.54375358793344e-14!GO:0016887;ATPase activity;3.22850774935061e-14!GO:0005783;endoplasmic reticulum;4.19894183212463e-14!GO:0006913;nucleocytoplasmic transport;4.2676027051242e-14!GO:0015630;microtubule cytoskeleton;4.31268632901896e-14!GO:0048193;Golgi vesicle transport;5.23084587316966e-14!GO:0044248;cellular catabolic process;6.1121850494293e-14!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);6.8474436766998e-14!GO:0050794;regulation of cellular process;8.45890253586517e-14!GO:0006333;chromatin assembly or disassembly;1.1295644517657e-13!GO:0051169;nuclear transport;1.36605859100105e-13!GO:0000074;regulation of progression through cell cycle;1.47519210438022e-13!GO:0051726;regulation of cell cycle;1.6037292548523e-13!GO:0000785;chromatin;1.6931461718553e-13!GO:0042623;ATPase activity, coupled;2.43595584813202e-13!GO:0044432;endoplasmic reticulum part;3.54998712173949e-13!GO:0005761;mitochondrial ribosome;3.92203400245416e-13!GO:0000313;organellar ribosome;3.92203400245416e-13!GO:0030964;NADH dehydrogenase complex (quinone);4.0914525642437e-13!GO:0045271;respiratory chain complex I;4.0914525642437e-13!GO:0005747;mitochondrial respiratory chain complex I;4.0914525642437e-13!GO:0042775;organelle ATP synthesis coupled electron transport;5.01720203382082e-13!GO:0042773;ATP synthesis coupled electron transport;5.01720203382082e-13!GO:0006464;protein modification process;6.26636824984645e-13!GO:0006366;transcription from RNA polymerase II promoter;6.45107331853773e-13!GO:0004386;helicase activity;6.74583408590786e-13!GO:0019222;regulation of metabolic process;7.31642652428053e-13!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);8.24503487626087e-13!GO:0005794;Golgi apparatus;9.56959072386128e-13!GO:0065004;protein-DNA complex assembly;9.829563260163e-13!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;1.21749693813153e-12!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.82315182809111e-12!GO:0051186;cofactor metabolic process;2.05704436356866e-12!GO:0043687;post-translational protein modification;2.1832127844012e-12!GO:0051082;unfolded protein binding;2.36267884584308e-12!GO:0005643;nuclear pore;4.24865829004457e-12!GO:0050657;nucleic acid transport;4.78646371046261e-12!GO:0051236;establishment of RNA localization;4.78646371046261e-12!GO:0050658;RNA transport;4.78646371046261e-12!GO:0006403;RNA localization;5.44460700847652e-12!GO:0003743;translation initiation factor activity;1.05360139130574e-11!GO:0006399;tRNA metabolic process;1.12860801815745e-11!GO:0000775;chromosome, pericentric region;1.31017954995919e-11!GO:0016568;chromatin modification;1.45621632730531e-11!GO:0016607;nuclear speck;2.11624095362214e-11!GO:0016192;vesicle-mediated transport;3.71030695457219e-11!GO:0006261;DNA-dependent DNA replication;4.0589669147499e-11!GO:0008639;small protein conjugating enzyme activity;5.17798940044533e-11!GO:0065002;intracellular protein transport across a membrane;5.58832208499218e-11!GO:0008026;ATP-dependent helicase activity;8.87758793123053e-11!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.50878673316495e-10!GO:0004842;ubiquitin-protein ligase activity;1.54839567496786e-10!GO:0017038;protein import;1.95647297123487e-10!GO:0006413;translational initiation;2.0702342631548e-10!GO:0016879;ligase activity, forming carbon-nitrogen bonds;2.69783872727777e-10!GO:0006350;transcription;3.03183280968166e-10!GO:0006364;rRNA processing;3.24369415450391e-10!GO:0031323;regulation of cellular metabolic process;4.18099360552459e-10!GO:0005819;spindle;4.6419545583612e-10!GO:0006732;coenzyme metabolic process;5.3641425538899e-10!GO:0051028;mRNA transport;5.68682441256881e-10!GO:0019787;small conjugating protein ligase activity;6.51501691794872e-10!GO:0003712;transcription cofactor activity;7.06950973145364e-10!GO:0006461;protein complex assembly;7.45560562585253e-10!GO:0006446;regulation of translational initiation;9.15230240831447e-10!GO:0046930;pore complex;9.42848165591729e-10!GO:0016072;rRNA metabolic process;1.0593102890603e-09!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.1578929310767e-09!GO:0006334;nucleosome assembly;1.34369974278833e-09!GO:0030532;small nuclear ribonucleoprotein complex;1.46717239680413e-09!GO:0031497;chromatin assembly;1.99545395706887e-09!GO:0016881;acid-amino acid ligase activity;2.00108573148198e-09!GO:0009055;electron carrier activity;2.27730540377647e-09!GO:0008565;protein transporter activity;2.55823444384195e-09!GO:0003697;single-stranded DNA binding;2.9168035364368e-09!GO:0050789;regulation of biological process;2.95140318620169e-09!GO:0005789;endoplasmic reticulum membrane;3.24678198190578e-09!GO:0005667;transcription factor complex;4.11682269962031e-09!GO:0051329;interphase of mitotic cell cycle;4.18392128125119e-09!GO:0006163;purine nucleotide metabolic process;4.41062075711104e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;4.57794533710451e-09!GO:0009259;ribonucleotide metabolic process;4.93202498685794e-09!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;6.5772467547516e-09!GO:0004812;aminoacyl-tRNA ligase activity;6.5772467547516e-09!GO:0016875;ligase activity, forming carbon-oxygen bonds;6.5772467547516e-09!GO:0043566;structure-specific DNA binding;1.02175851516045e-08!GO:0005793;ER-Golgi intermediate compartment;1.46894743839349e-08!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.61935446195371e-08!GO:0005813;centrosome;1.68230755504949e-08!GO:0051325;interphase;1.89972753205835e-08!GO:0000075;cell cycle checkpoint;2.2979851105016e-08!GO:0031324;negative regulation of cellular metabolic process;2.2979851105016e-08!GO:0043038;amino acid activation;2.42320941333034e-08!GO:0006418;tRNA aminoacylation for protein translation;2.42320941333034e-08!GO:0043039;tRNA aminoacylation;2.42320941333034e-08!GO:0032446;protein modification by small protein conjugation;2.4713333793727e-08!GO:0009150;purine ribonucleotide metabolic process;3.36723916442769e-08!GO:0016567;protein ubiquitination;3.44852017166371e-08!GO:0010468;regulation of gene expression;3.44852017166371e-08!GO:0016740;transferase activity;3.67921623597495e-08!GO:0006164;purine nucleotide biosynthetic process;3.68167610571826e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;4.15841748684294e-08!GO:0005815;microtubule organizing center;4.84989934974475e-08!GO:0032774;RNA biosynthetic process;4.97284536729921e-08!GO:0007051;spindle organization and biogenesis;5.71223022686257e-08!GO:0051170;nuclear import;5.73554079878612e-08!GO:0016779;nucleotidyltransferase activity;6.71654744735602e-08!GO:0006351;transcription, DNA-dependent;7.69387012393987e-08!GO:0048523;negative regulation of cellular process;7.70225869744334e-08!GO:0009260;ribonucleotide biosynthetic process;8.00057845546978e-08!GO:0009141;nucleoside triphosphate metabolic process;9.67707955270681e-08!GO:0003677;DNA binding;9.75449051160509e-08!GO:0006606;protein import into nucleus;1.06750687170581e-07!GO:0009199;ribonucleoside triphosphate metabolic process;1.28148797704264e-07!GO:0000245;spliceosome assembly;1.33027486736404e-07!GO:0009060;aerobic respiration;1.40333669640351e-07!GO:0012501;programmed cell death;1.74929546325518e-07!GO:0048475;coated membrane;1.93956905105364e-07!GO:0030117;membrane coat;1.93956905105364e-07!GO:0006888;ER to Golgi vesicle-mediated transport;2.39864876438801e-07!GO:0003682;chromatin binding;2.39864876438801e-07!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.44582903857802e-07!GO:0006915;apoptosis;2.48041163735461e-07!GO:0015986;ATP synthesis coupled proton transport;2.56182332566992e-07!GO:0015985;energy coupled proton transport, down electrochemical gradient;2.56182332566992e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;2.58093564311209e-07!GO:0009144;purine nucleoside triphosphate metabolic process;2.58093564311209e-07!GO:0009152;purine ribonucleotide biosynthetic process;2.75781189349039e-07!GO:0000151;ubiquitin ligase complex;3.1887308741062e-07!GO:0046034;ATP metabolic process;3.20340687165145e-07!GO:0009056;catabolic process;3.29094359197512e-07!GO:0009892;negative regulation of metabolic process;3.35747049059914e-07!GO:0030120;vesicle coat;3.65935967375506e-07!GO:0030662;coated vesicle membrane;3.65935967375506e-07!GO:0005657;replication fork;4.07572450456211e-07!GO:0044431;Golgi apparatus part;5.0143611069889e-07!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;5.5578936928606e-07!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;5.66106218612316e-07!GO:0045786;negative regulation of progression through cell cycle;6.88621809302342e-07!GO:0016772;transferase activity, transferring phosphorus-containing groups;7.16547510283133e-07!GO:0045333;cellular respiration;7.60743698911481e-07!GO:0031202;RNA splicing factor activity, transesterification mechanism;8.2347839513164e-07!GO:0003924;GTPase activity;8.62435622979438e-07!GO:0045449;regulation of transcription;8.84977994277027e-07!GO:0005874;microtubule;1.10652129770367e-06!GO:0009142;nucleoside triphosphate biosynthetic process;1.15654876568647e-06!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.15654876568647e-06!GO:0006793;phosphorus metabolic process;1.17523563265173e-06!GO:0006796;phosphate metabolic process;1.17523563265173e-06!GO:0019829;cation-transporting ATPase activity;1.26595739698235e-06!GO:0051188;cofactor biosynthetic process;1.55658198640809e-06!GO:0008219;cell death;1.62734650305368e-06!GO:0016265;death;1.62734650305368e-06!GO:0045259;proton-transporting ATP synthase complex;1.70142344803987e-06!GO:0008094;DNA-dependent ATPase activity;1.71849906328542e-06!GO:0007005;mitochondrion organization and biogenesis;1.73838230675445e-06!GO:0005839;proteasome core complex (sensu Eukaryota);2.08066214847613e-06!GO:0006099;tricarboxylic acid cycle;2.13496946590705e-06!GO:0046356;acetyl-CoA catabolic process;2.13496946590705e-06!GO:0043623;cellular protein complex assembly;2.23714493598405e-06!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;2.33802834324656e-06!GO:0009145;purine nucleoside triphosphate biosynthetic process;2.33802834324656e-06!GO:0015078;hydrogen ion transmembrane transporter activity;2.44768089786988e-06!GO:0006357;regulation of transcription from RNA polymerase II promoter;2.4548087983343e-06!GO:0005768;endosome;2.50182625752576e-06!GO:0006754;ATP biosynthetic process;2.5864361182003e-06!GO:0006753;nucleoside phosphate metabolic process;2.5864361182003e-06!GO:0007059;chromosome segregation;3.16985006723138e-06!GO:0016481;negative regulation of transcription;3.29151390631035e-06!GO:0016310;phosphorylation;3.35346880652322e-06!GO:0005798;Golgi-associated vesicle;3.43308359234134e-06!GO:0016469;proton-transporting two-sector ATPase complex;3.52329703306605e-06!GO:0003899;DNA-directed RNA polymerase activity;3.80441558069472e-06!GO:0051246;regulation of protein metabolic process;4.14418128738328e-06!GO:0005788;endoplasmic reticulum lumen;4.18580527859299e-06!GO:0051427;hormone receptor binding;4.2016430129478e-06!GO:0004298;threonine endopeptidase activity;5.1925122797697e-06!GO:0007010;cytoskeleton organization and biogenesis;6.15700685955517e-06!GO:0048519;negative regulation of biological process;6.39115777711764e-06!GO:0006084;acetyl-CoA metabolic process;7.20264218609182e-06!GO:0006752;group transfer coenzyme metabolic process;8.1118950259405e-06!GO:0003724;RNA helicase activity;8.30486857491183e-06!GO:0016563;transcription activator activity;8.7425623979571e-06!GO:0006302;double-strand break repair;9.85172973987625e-06!GO:0009109;coenzyme catabolic process;1.0500391591033e-05!GO:0035257;nuclear hormone receptor binding;1.0500391591033e-05!GO:0006355;regulation of transcription, DNA-dependent;1.09077509990583e-05!GO:0006613;cotranslational protein targeting to membrane;1.25126379174304e-05!GO:0009117;nucleotide metabolic process;1.29698483762233e-05!GO:0030867;rough endoplasmic reticulum membrane;1.31697157623256e-05!GO:0009108;coenzyme biosynthetic process;1.32860346316068e-05!GO:0051052;regulation of DNA metabolic process;1.32860346316068e-05!GO:0051168;nuclear export;1.34693137354709e-05!GO:0051187;cofactor catabolic process;1.38230146309326e-05!GO:0016363;nuclear matrix;1.48180262414549e-05!GO:0000776;kinetochore;2.20344467667781e-05!GO:0003713;transcription coactivator activity;2.27446508327961e-05!GO:0005905;coated pit;2.50278447754684e-05!GO:0016564;transcription repressor activity;2.95441736679056e-05!GO:0006414;translational elongation;3.13009509064853e-05!GO:0005762;mitochondrial large ribosomal subunit;3.81035042347236e-05!GO:0000315;organellar large ribosomal subunit;3.81035042347236e-05!GO:0019899;enzyme binding;4.20589214502106e-05!GO:0015980;energy derivation by oxidation of organic compounds;4.58166078546793e-05!GO:0000139;Golgi membrane;4.60027091288915e-05!GO:0000082;G1/S transition of mitotic cell cycle;4.65624059999719e-05!GO:0043284;biopolymer biosynthetic process;4.86921747231878e-05!GO:0008654;phospholipid biosynthetic process;5.01423700051138e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;5.95491875370672e-05!GO:0007017;microtubule-based process;6.2067278038757e-05!GO:0007093;mitotic cell cycle checkpoint;6.91741076881631e-05!GO:0007088;regulation of mitosis;7.38280867258296e-05!GO:0006383;transcription from RNA polymerase III promoter;7.44981226820521e-05!GO:0015631;tubulin binding;9.04086056748506e-05!GO:0003714;transcription corepressor activity;9.45500517290821e-05!GO:0005525;GTP binding;0.000100326529885469!GO:0015077;monovalent inorganic cation transmembrane transporter activity;0.000100983072890227!GO:0044452;nucleolar part;0.000106377673047733!GO:0008033;tRNA processing;0.000129242395861014!GO:0065007;biological regulation;0.000135594484869921!GO:0003729;mRNA binding;0.000146261736708244!GO:0008022;protein C-terminus binding;0.000162030416477488!GO:0005791;rough endoplasmic reticulum;0.000170107446437829!GO:0000059;protein import into nucleus, docking;0.000174633884916287!GO:0016853;isomerase activity;0.000184117040388465!GO:0000786;nucleosome;0.000187908766046412!GO:0043021;ribonucleoprotein binding;0.000188367290742959!GO:0007052;mitotic spindle organization and biogenesis;0.000203755722272363!GO:0000228;nuclear chromosome;0.000207674434343014!GO:0006310;DNA recombination;0.000228706078146463!GO:0045454;cell redox homeostasis;0.000235535672796544!GO:0031968;organelle outer membrane;0.000235535672796544!GO:0016787;hydrolase activity;0.000255342732501783!GO:0044440;endosomal part;0.000258647727194555!GO:0010008;endosome membrane;0.000258647727194555!GO:0031988;membrane-bound vesicle;0.00026881342888863!GO:0003684;damaged DNA binding;0.000291255459632833!GO:0006612;protein targeting to membrane;0.000292579478063134!GO:0031252;leading edge;0.000342813596815498!GO:0003690;double-stranded DNA binding;0.000349993178128809!GO:0031072;heat shock protein binding;0.000350058815089573!GO:0005770;late endosome;0.000351060981791997!GO:0019867;outer membrane;0.000359394113524529!GO:0006275;regulation of DNA replication;0.000368702021316885!GO:0016023;cytoplasmic membrane-bound vesicle;0.000373613476300447!GO:0008186;RNA-dependent ATPase activity;0.000390235970852205!GO:0006338;chromatin remodeling;0.000417339367421852!GO:0005741;mitochondrial outer membrane;0.000418702968516754!GO:0000314;organellar small ribosomal subunit;0.000418702968516754!GO:0005763;mitochondrial small ribosomal subunit;0.000418702968516754!GO:0005769;early endosome;0.000428588293640633!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000430515679121159!GO:0006352;transcription initiation;0.000431732122716391!GO:0051789;response to protein stimulus;0.000442212560228687!GO:0006986;response to unfolded protein;0.000442212560228687!GO:0008092;cytoskeletal protein binding;0.000508851018850229!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.000508851018850229!GO:0006402;mRNA catabolic process;0.000509815937032797!GO:0006839;mitochondrial transport;0.000539011271749095!GO:0003678;DNA helicase activity;0.000549049251387083!GO:0005885;Arp2/3 protein complex;0.000581841361214507!GO:0005684;U2-dependent spliceosome;0.000581841361214507!GO:0016859;cis-trans isomerase activity;0.000613445999690938!GO:0004674;protein serine/threonine kinase activity;0.000624012319253433!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000640354661050225!GO:0005637;nuclear inner membrane;0.000648718982712159!GO:0032561;guanyl ribonucleotide binding;0.000671370816065047!GO:0019001;guanyl nucleotide binding;0.000671370816065047!GO:0030118;clathrin coat;0.000678369477562435!GO:0033116;ER-Golgi intermediate compartment membrane;0.000688877238825932!GO:0005876;spindle microtubule;0.000701767927460244!GO:0007050;cell cycle arrest;0.000750037152019522!GO:0008250;oligosaccharyl transferase complex;0.000770892637558853!GO:0000049;tRNA binding;0.00082488243990108!GO:0004527;exonuclease activity;0.000893152660802063!GO:0016126;sterol biosynthetic process;0.000911691374746162!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00097527705379498!GO:0042981;regulation of apoptosis;0.00101019765698621!GO:0019783;small conjugating protein-specific protease activity;0.00101205910358936!GO:0031982;vesicle;0.00102200707410696!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.00104540405412844!GO:0030658;transport vesicle membrane;0.00108727665904752!GO:0004004;ATP-dependent RNA helicase activity;0.00108727665904752!GO:0043067;regulation of programmed cell death;0.00108727665904752!GO:0004576;oligosaccharyl transferase activity;0.00111607617406215!GO:0003702;RNA polymerase II transcription factor activity;0.00115237775539864!GO:0046474;glycerophospholipid biosynthetic process;0.00116575879959215!GO:0030880;RNA polymerase complex;0.00117697281218017!GO:0004843;ubiquitin-specific protease activity;0.00119459879832908!GO:0005048;signal sequence binding;0.0012226785504591!GO:0000922;spindle pole;0.00125146064816188!GO:0016741;transferase activity, transferring one-carbon groups;0.00129597099428088!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.00129597099428088!GO:0032508;DNA duplex unwinding;0.00130343718972342!GO:0032392;DNA geometric change;0.00130343718972342!GO:0030133;transport vesicle;0.00135017695080428!GO:0031124;mRNA 3'-end processing;0.00136498212957221!GO:0003746;translation elongation factor activity;0.00137103084747887!GO:0046489;phosphoinositide biosynthetic process;0.00139652620066047!GO:0016790;thiolester hydrolase activity;0.00139907335112519!GO:0006611;protein export from nucleus;0.00140221121117793!GO:0030176;integral to endoplasmic reticulum membrane;0.00140905170503414!GO:0048471;perinuclear region of cytoplasm;0.00152271273303837!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00152387756241922!GO:0045892;negative regulation of transcription, DNA-dependent;0.0015404383108977!GO:0008168;methyltransferase activity;0.0015404383108977!GO:0048500;signal recognition particle;0.00154543375549562!GO:0031410;cytoplasmic vesicle;0.00162671830689016!GO:0051101;regulation of DNA binding;0.00166281761163086!GO:0008361;regulation of cell size;0.00167461036545921!GO:0043596;nuclear replication fork;0.00169661460804177!GO:0043069;negative regulation of programmed cell death;0.00179063947195562!GO:0000819;sister chromatid segregation;0.00180011651405536!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.00184213514626364!GO:0030660;Golgi-associated vesicle membrane;0.00189659504792877!GO:0016049;cell growth;0.00193081222759867!GO:0004221;ubiquitin thiolesterase activity;0.00196076495902073!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00209139738310876!GO:0006268;DNA unwinding during replication;0.00209723283960458!GO:0006270;DNA replication initiation;0.00211832803179054!GO:0006401;RNA catabolic process;0.0021234552313854!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00225721821724329!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00225721821724329!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00225721821724329!GO:0000070;mitotic sister chromatid segregation;0.0023722785010124!GO:0043681;protein import into mitochondrion;0.0025382836395799!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00254089013854522!GO:0043066;negative regulation of apoptosis;0.002606840087342!GO:0008312;7S RNA binding;0.00260890930737023!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00261122684252053!GO:0000428;DNA-directed RNA polymerase complex;0.00261122684252053!GO:0018196;peptidyl-asparagine modification;0.0026818656361645!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0026818656361645!GO:0035258;steroid hormone receptor binding;0.00279231378236524!GO:0006626;protein targeting to mitochondrion;0.0027942148487772!GO:0006695;cholesterol biosynthetic process;0.00279841613444736!GO:0007006;mitochondrial membrane organization and biogenesis;0.00279841613444736!GO:0006916;anti-apoptosis;0.00294801155364585!GO:0051252;regulation of RNA metabolic process;0.00299044664884508!GO:0000792;heterochromatin;0.00305052705993642!GO:0006892;post-Golgi vesicle-mediated transport;0.00311624785882811!GO:0030036;actin cytoskeleton organization and biogenesis;0.00314978069190404!GO:0030521;androgen receptor signaling pathway;0.00314978069190404!GO:0000910;cytokinesis;0.00317219794849817!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00320733421151677!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00320733421151677!GO:0006891;intra-Golgi vesicle-mediated transport;0.00321524429801163!GO:0009165;nucleotide biosynthetic process;0.00327282811183989!GO:0048487;beta-tubulin binding;0.00346477389857631!GO:0042393;histone binding;0.00346826960620863!GO:0006144;purine base metabolic process;0.00353873068064223!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00354968516510485!GO:0000287;magnesium ion binding;0.00356700565364763!GO:0030132;clathrin coat of coated pit;0.00368647670811344!GO:0006405;RNA export from nucleus;0.00387455994762171!GO:0001558;regulation of cell growth;0.00393313054707082!GO:0008017;microtubule binding;0.00402323996693129!GO:0051287;NAD binding;0.00440633783630289!GO:0043601;nuclear replisome;0.00440633783630289!GO:0030894;replisome;0.00440633783630289!GO:0008139;nuclear localization sequence binding;0.00442996664941745!GO:0016251;general RNA polymerase II transcription factor activity;0.00444275173172462!GO:0009112;nucleobase metabolic process;0.00446258837771168!GO:0030134;ER to Golgi transport vesicle;0.00455594319145808!GO:0051539;4 iron, 4 sulfur cluster binding;0.00487685377102623!GO:0031123;RNA 3'-end processing;0.00497826706469402!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00497826706469402!GO:0046966;thyroid hormone receptor binding;0.00498029679482395!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00498029679482395!GO:0045047;protein targeting to ER;0.00498029679482395!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00498799050469039!GO:0030663;COPI coated vesicle membrane;0.00498799050469039!GO:0030126;COPI vesicle coat;0.00498799050469039!GO:0042802;identical protein binding;0.00531646998325519!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00541556188492312!GO:0046483;heterocycle metabolic process;0.00545487845988077!GO:0045936;negative regulation of phosphate metabolic process;0.00581253095798207!GO:0045893;positive regulation of transcription, DNA-dependent;0.0060738425555444!GO:0051098;regulation of binding;0.00621894087124485!GO:0000178;exosome (RNase complex);0.00634680196716566!GO:0006595;polyamine metabolic process;0.00663131894138992!GO:0051540;metal cluster binding;0.00667458349236198!GO:0051536;iron-sulfur cluster binding;0.00667458349236198!GO:0031570;DNA integrity checkpoint;0.00683715535961837!GO:0044454;nuclear chromosome part;0.00698229296550128!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.00726339676318834!GO:0045045;secretory pathway;0.00727446286914848!GO:0005669;transcription factor TFIID complex;0.00769809759202626!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.00785597845500854!GO:0046822;regulation of nucleocytoplasmic transport;0.00810247133428746!GO:0043130;ubiquitin binding;0.00814579698890095!GO:0032182;small conjugating protein binding;0.00814579698890095!GO:0006607;NLS-bearing substrate import into nucleus;0.00816143125281143!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.00825659556052083!GO:0015399;primary active transmembrane transporter activity;0.00825659556052083!GO:0006284;base-excision repair;0.00825873163767254!GO:0009303;rRNA transcription;0.008502898204543!GO:0030127;COPII vesicle coat;0.00851025734164933!GO:0012507;ER to Golgi transport vesicle membrane;0.00851025734164933!GO:0051087;chaperone binding;0.00855031717102063!GO:0003711;transcription elongation regulator activity;0.00862485205289291!GO:0005832;chaperonin-containing T-complex;0.00872695755724516!GO:0016197;endosome transport;0.0087428860041003!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00878142672988354!GO:0019206;nucleoside kinase activity;0.0091381786105751!GO:0006378;mRNA polyadenylation;0.00917794327486867!GO:0051920;peroxiredoxin activity;0.00925730338413397!GO:0007346;regulation of progression through mitotic cell cycle;0.00946973612845304!GO:0030518;steroid hormone receptor signaling pathway;0.00950461882127474!GO:0000725;recombinational repair;0.00951377061936693!GO:0000724;double-strand break repair via homologous recombination;0.00951377061936693!GO:0042770;DNA damage response, signal transduction;0.00996943007331736!GO:0046467;membrane lipid biosynthetic process;0.0100503370736013!GO:0005853;eukaryotic translation elongation factor 1 complex;0.0101244910680176!GO:0006818;hydrogen transport;0.0102945380442195!GO:0006506;GPI anchor biosynthetic process;0.0103887313132901!GO:0016272;prefoldin complex;0.0104147254302087!GO:0008286;insulin receptor signaling pathway;0.0104558373112492!GO:0030119;AP-type membrane coat adaptor complex;0.0105064002603708!GO:0016301;kinase activity;0.0105345206542075!GO:0006091;generation of precursor metabolites and energy;0.0107754688789784!GO:0015992;proton transport;0.0108147747122505!GO:0005862;muscle thin filament tropomyosin;0.0109603333680409!GO:0003923;GPI-anchor transamidase activity;0.0109626191788174!GO:0016255;attachment of GPI anchor to protein;0.0109626191788174!GO:0042765;GPI-anchor transamidase complex;0.0109626191788174!GO:0008276;protein methyltransferase activity;0.0109836455667574!GO:0030384;phosphoinositide metabolic process;0.0109836455667574!GO:0046112;nucleobase biosynthetic process;0.011293983665302!GO:0016044;membrane organization and biogenesis;0.0113760737553793!GO:0016584;nucleosome positioning;0.0114475653741591!GO:0006505;GPI anchor metabolic process;0.0117027410771823!GO:0030027;lamellipodium;0.0118019209971384!GO:0005773;vacuole;0.0118593638403358!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;0.0120211849229372!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.0120552671587781!GO:0006650;glycerophospholipid metabolic process;0.0120552671587781!GO:0019843;rRNA binding;0.0121237926102388!GO:0008097;5S rRNA binding;0.0121761598871788!GO:0044262;cellular carbohydrate metabolic process;0.0121778100903227!GO:0030137;COPI-coated vesicle;0.0124704647145037!GO:0043189;H4/H2A histone acetyltransferase complex;0.0127046877320364!GO:0009116;nucleoside metabolic process;0.012750486749243!GO:0016491;oxidoreductase activity;0.0128722558741934!GO:0006497;protein amino acid lipidation;0.0129241157530451!GO:0030029;actin filament-based process;0.0129655380290305!GO:0006367;transcription initiation from RNA polymerase II promoter;0.013074386199275!GO:0008287;protein serine/threonine phosphatase complex;0.0132094849817716!GO:0030131;clathrin adaptor complex;0.0132094849817716!GO:0030125;clathrin vesicle coat;0.013374512097658!GO:0030665;clathrin coated vesicle membrane;0.013374512097658!GO:0004003;ATP-dependent DNA helicase activity;0.0135398476691354!GO:0004518;nuclease activity;0.013811667608227!GO:0042326;negative regulation of phosphorylation;0.0138476178056601!GO:0016579;protein deubiquitination;0.01443826732216!GO:0000339;RNA cap binding;0.0144821080136284!GO:0035267;NuA4 histone acetyltransferase complex;0.014665117565878!GO:0006376;mRNA splice site selection;0.0147773377775973!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0147773377775973!GO:0008180;signalosome;0.0149714279884281!GO:0051053;negative regulation of DNA metabolic process;0.0150945062392948!GO:0005875;microtubule associated complex;0.0151283539887501!GO:0007264;small GTPase mediated signal transduction;0.0157707371651003!GO:0008408;3'-5' exonuclease activity;0.0157884951799888!GO:0016585;chromatin remodeling complex;0.0161523838685804!GO:0000123;histone acetyltransferase complex;0.0162016123869507!GO:0030496;midbody;0.0165815833827749!GO:0000152;nuclear ubiquitin ligase complex;0.0165815833827749!GO:0043022;ribosome binding;0.0170400970962397!GO:0004532;exoribonuclease activity;0.0171054988684292!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0171054988684292!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.0185058767592778!GO:0000086;G2/M transition of mitotic cell cycle;0.0189054610610939!GO:0000793;condensed chromosome;0.0193537494528862!GO:0045941;positive regulation of transcription;0.0199764614209726!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0201341691055603!GO:0005869;dynactin complex;0.0205151558005303!GO:0005663;DNA replication factor C complex;0.0207008001290762!GO:0031577;spindle checkpoint;0.0207563838593643!GO:0043488;regulation of mRNA stability;0.0207997074642031!GO:0043487;regulation of RNA stability;0.0207997074642031!GO:0008536;Ran GTPase binding;0.0209019373393885!GO:0032507;maintenance of cellular protein localization;0.0211326599000149!GO:0005652;nuclear lamina;0.0211832366946428!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0215542388749365!GO:0015002;heme-copper terminal oxidase activity;0.0215542388749365!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0215542388749365!GO:0004129;cytochrome-c oxidase activity;0.0215542388749365!GO:0008270;zinc ion binding;0.0222786627314892!GO:0008610;lipid biosynthetic process;0.0223452959966909!GO:0043624;cellular protein complex disassembly;0.0225338712901331!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0234121767688398!GO:0007021;tubulin folding;0.0234356709428479!GO:0051059;NF-kappaB binding;0.0234544584582235!GO:0017166;vinculin binding;0.0237745222307048!GO:0040029;regulation of gene expression, epigenetic;0.0240288632531731!GO:0000084;S phase of mitotic cell cycle;0.0240506629126848!GO:0065009;regulation of a molecular function;0.0246107250727544!GO:0050681;androgen receptor binding;0.0248735962959204!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0249378881962017!GO:0046426;negative regulation of JAK-STAT cascade;0.0249484870299213!GO:0008538;proteasome activator activity;0.0256318237058602!GO:0000077;DNA damage checkpoint;0.0261581503571042!GO:0000118;histone deacetylase complex;0.0265714226876211!GO:0003756;protein disulfide isomerase activity;0.0267039518255956!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0267039518255956!GO:0032984;macromolecular complex disassembly;0.0270310573010235!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0271856410949984!GO:0030140;trans-Golgi network transport vesicle;0.0273714476284073!GO:0051320;S phase;0.0280028625228336!GO:0050178;phenylpyruvate tautomerase activity;0.0286097625307571!GO:0031625;ubiquitin protein ligase binding;0.0286851474285816!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0287146742273518!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.0289202546413618!GO:0042791;5S class rRNA transcription;0.0293671161096896!GO:0000127;transcription factor TFIIIC complex;0.0293671161096896!GO:0042797;tRNA transcription from RNA polymerase III promoter;0.0293671161096896!GO:0003887;DNA-directed DNA polymerase activity;0.0294766931392146!GO:0006289;nucleotide-excision repair;0.0295194451687116!GO:0006672;ceramide metabolic process;0.0298419101353921!GO:0001832;blastocyst growth;0.0301644100250192!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.0303353293593091!GO:0046128;purine ribonucleoside metabolic process;0.0311900730721931!GO:0042278;purine nucleoside metabolic process;0.0311900730721931!GO:0043241;protein complex disassembly;0.0319155135885224!GO:0000209;protein polyubiquitination;0.0319155135885224!GO:0009113;purine base biosynthetic process;0.031936346692941!GO:0000726;non-recombinational repair;0.0323501781949238!GO:0043433;negative regulation of transcription factor activity;0.0324949751000473!GO:0009304;tRNA transcription;0.0326534045049741!GO:0005784;translocon complex;0.0337364756176763!GO:0006301;postreplication repair;0.0337364756176763!GO:0042158;lipoprotein biosynthetic process;0.0338238148955476!GO:0044438;microbody part;0.0338238148955476!GO:0044439;peroxisomal part;0.0338238148955476!GO:0008234;cysteine-type peptidase activity;0.0344807336244703!GO:0000323;lytic vacuole;0.0347923718445276!GO:0005764;lysosome;0.0347923718445276!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0347923718445276!GO:0010257;NADH dehydrogenase complex assembly;0.0347923718445276!GO:0033108;mitochondrial respiratory chain complex assembly;0.0347923718445276!GO:0005856;cytoskeleton;0.0349745741579842!GO:0030145;manganese ion binding;0.0350815896928773!GO:0008475;procollagen-lysine 5-dioxygenase activity;0.0357373279641504!GO:0043492;ATPase activity, coupled to movement of substances;0.0357373279641504!GO:0003857;3-hydroxyacyl-CoA dehydrogenase activity;0.0388508099741711!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.0393131587677241!GO:0008156;negative regulation of DNA replication;0.0396514984733224!GO:0030508;thiol-disulfide exchange intermediate activity;0.0398359092591832!GO:0016408;C-acyltransferase activity;0.0405458516337983!GO:0022411;cellular component disassembly;0.0407518307673279!GO:0043631;RNA polyadenylation;0.0411073486345849!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.0413425680289407!GO:0005938;cell cortex;0.0417879907150168!GO:0051651;maintenance of cellular localization;0.0417879907150168!GO:0045792;negative regulation of cell size;0.0419459562339257!GO:0030149;sphingolipid catabolic process;0.0419843447932641!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0423753479445844!GO:0031227;intrinsic to endoplasmic reticulum membrane;0.0426719877871099!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0432835180951405!GO:0004347;glucose-6-phosphate isomerase activity;0.0435703752017853!GO:0022890;inorganic cation transmembrane transporter activity;0.0437295523251831!GO:0019752;carboxylic acid metabolic process;0.0457514691022339!GO:0006740;NADPH regeneration;0.0458709897956408!GO:0006098;pentose-phosphate shunt;0.0458709897956408!GO:0003725;double-stranded RNA binding;0.0460912288610529!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0460912288610529!GO:0009451;RNA modification;0.0466456435736822!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.0467023929886431!GO:0005881;cytoplasmic microtubule;0.0470935908323723!GO:0051656;establishment of organelle localization;0.0472587066846579!GO:0031903;microbody membrane;0.0474100810014687!GO:0005778;peroxisomal membrane;0.0474100810014687!GO:0042026;protein refolding;0.0474100810014687!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0478473017220752!GO:0004185;serine carboxypeptidase activity;0.0488818512653832!GO:0030320;cellular monovalent inorganic anion homeostasis;0.0488818512653832!GO:0055083;monovalent inorganic anion homeostasis;0.0488818512653832!GO:0055064;chloride ion homeostasis;0.0488818512653832!GO:0030644;cellular chloride ion homeostasis;0.0488818512653832!GO:0005758;mitochondrial intermembrane space;0.048968356060306!GO:0031371;ubiquitin conjugating enzyme complex;0.0491108267445326!GO:0031301;integral to organelle membrane;0.0495962592094914!GO:0030308;negative regulation of cell growth;0.0497669432463015 | |||
|sample_id=12760 | |sample_id=12760 | ||
|sample_note= | |sample_note= | ||
| Line 75: | Line 104: | ||
|sample_strain= | |sample_strain= | ||
|sample_tissue= | |sample_tissue= | ||
|time= 00hr00min | |||
|timecourse=Saos_calcification | |||
|top_motifs=PDX1:2.71420605908;TFDP1:2.09281133555;VSX1,2:1.83718861584;HOX{A4,D4}:1.63537506329;NFY{A,B,C}:1.59149270321;NKX2-3_NKX2-5:1.58792111239;E2F1..5:1.52684168045;NRF1:1.3753150316;NKX3-1:1.34059693162;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.32624644011;ZNF384:1.2095071455;PITX1..3:1.20271536682;ZNF143:1.17966996568;POU1F1:1.17778368796;PRRX1,2:1.09385797379;HIC1:1.08892499643;TOPORS:1.03092838818;EVI1:1.01097659789;EN1,2:1.00742457964;NFIX:0.972374942907;NKX6-1,2:0.968265473944;BREu{core}:0.938339873335;YY1:0.899682378467;GFI1:0.861869750318;CDC5L:0.788583213401;MEF2{A,B,C,D}:0.774645394712;RXR{A,B,G}:0.77330885815;PAX8:0.754509997334;SOX17:0.743772641805;NKX2-1,4:0.73549613734;FOXQ1:0.728222681513;IKZF2:0.727151044681;HIF1A:0.711209255189;PAX6:0.695058448762;PAX3,7:0.680968263199;FOXD3:0.67984146901;CUX2:0.672975236211;HES1:0.653863009287;MZF1:0.628806908873;T:0.576098790214;PAX1,9:0.566936470776;NR1H4:0.555955401983;PAX4:0.552787649793;PAX2:0.523328669091;MYB:0.517014026961;ZFP161:0.511782631308;FOXM1:0.502196647674;TFAP2B:0.477166298001;RREB1:0.455530948378;AIRE:0.452118800326;ZNF423:0.448463120228;FOXA2:0.435984968897;SOX{8,9,10}:0.408954208165;ATF4:0.405997098471;SP1:0.396419255216;PBX1:0.394849321674;LHX3,4:0.391959174708;XCPE1{core}:0.388009822123;ZBTB16:0.385702323615;STAT5{A,B}:0.3826276238;CDX1,2,4:0.373895080199;NFE2L2:0.373784615645;TEF:0.370197603629;TEAD1:0.366614791962;AHR_ARNT_ARNT2:0.362517816927;FOXP1:0.361302811122;NR3C1:0.348588782154;POU3F1..4:0.314760916496;UFEwm:0.303996537454;ELK1,4_GABP{A,B1}:0.30310082923;NR5A1,2:0.302962748798;TGIF1:0.277426404623;NANOG:0.276690802098;POU6F1:0.254360179761;PATZ1:0.251351329059;LEF1_TCF7_TCF7L1,2:0.243785999939;EGR1..3:0.198420927826;PRDM1:0.192616196806;NR6A1:0.190630432021;GTF2I:0.189542199632;ONECUT1,2:0.18663055944;ZIC1..3:0.186217168203;ESR1:0.167519114696;KLF4:0.162543737955;ATF6:0.156330187004;JUN:0.145483329583;FOX{F1,F2,J1}:0.127049447291;RUNX1..3:0.116632158526;SREBF1,2:0.114687441601;STAT1,3:0.100194229964;MYBL2:0.0955178803421;GATA4:0.0756370600894;ZBTB6:0.0649386532856;ATF5_CREB3:0.0391913874369;CREB1:0.0170768887022;NFE2L1:0.00881544892719;OCT4_SOX2{dimer}:-0.00222430644259;MED-1{core}:-0.0191878841013;TBX4,5:-0.0263206906881;MTE{core}:-0.0322340085668;HOX{A5,B5}:-0.035462173424;GTF2A1,2:-0.048043655742;IKZF1:-0.0597883433338;ARID5B:-0.0616627365095;DBP:-0.0658243752017;FOXP3:-0.0690026415995;FOXN1:-0.0824887675871;RBPJ:-0.0899549926312;HNF1A:-0.100009552996;MYFfamily:-0.106097904704;XBP1:-0.111152623675;RFX1:-0.117728018216;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.131146841899;ESRRA:-0.134057550846;GFI1B:-0.142566574794;NFE2:-0.149557398446;MAZ:-0.149602927613;TFAP4:-0.156859125014;ALX4:-0.170449065604;GZF1:-0.174503961031;EBF1:-0.174904538908;HNF4A_NR2F1,2:-0.186254107878;FOXL1:-0.188243834325;BACH2:-0.20937490508;REST:-0.231874870267;CRX:-0.232483979801;bHLH_family:-0.243604141438;GLI1..3:-0.25001179718;RFX2..5_RFXANK_RFXAP:-0.251212190166;POU5F1:-0.252662923945;AR:-0.253557370791;FOSL2:-0.25914869082;IRF7:-0.26501547727;FOX{I1,J2}:-0.269469045817;RORA:-0.27364469387;GCM1,2:-0.286776307585;FOS_FOS{B,L1}_JUN{B,D}:-0.29695576459;DMAP1_NCOR{1,2}_SMARC:-0.297622434664;SOX5:-0.317105082548;NKX3-2:-0.317966003168;GATA6:-0.324678985752;ZNF238:-0.335830355222;TFCP2:-0.338932359204;ADNP_IRX_SIX_ZHX:-0.358987514919;HLF:-0.372716919453;TLX1..3_NFIC{dimer}:-0.374701937201;TFAP2{A,C}:-0.378815608946;HOXA9_MEIS1:-0.390481382785;SOX2:-0.416625805828;NHLH1,2:-0.438955543125;ELF1,2,4:-0.445177084925;SMAD1..7,9:-0.4597195042;RXRA_VDR{dimer}:-0.468785979958;NFIL3:-0.476457314082;TP53:-0.489444098372;NFKB1_REL_RELA:-0.49608558489;PAX5:-0.502853326236;SRF:-0.503967982841;MTF1:-0.520002021062;MYOD1:-0.527148276108;ZNF148:-0.528019029815;TAL1_TCF{3,4,12}:-0.52862483224;IRF1,2:-0.535958409356;SNAI1..3:-0.543362110545;SPIB:-0.549783666409;MAFB:-0.557412843889;SPI1:-0.570350067031;BPTF:-0.587047182847;SPZ1:-0.61447061436;LMO2:-0.653079078502;ZEB1:-0.653748487161;HAND1,2:-0.668497142314;POU2F1..3:-0.670762286279;ATF2:-0.705760257722;NKX2-2,8:-0.741962221432;ALX1:-0.751608902648;HMGA1,2:-0.770391221143;ETS1,2:-0.779958781901;NANOG{mouse}:-0.817700339313;PPARG:-0.819028518297;HMX1:-0.85176513836;FOX{D1,D2}:-0.86349801592;CEBPA,B_DDIT3:-0.876610061171;HOX{A6,A7,B6,B7}:-0.91385263909;STAT2,4,6:-0.955940557821;HBP1_HMGB_SSRP1_UBTF:-1.05558553167;FOXO1,3,4:-1.22625889201;HSF1,2:-1.2319651436;TBP:-1.25287166499;NFATC1..3:-1.26722244612;EP300:-1.33588564296;TLX2:-1.37007261095 | |top_motifs=PDX1:2.71420605908;TFDP1:2.09281133555;VSX1,2:1.83718861584;HOX{A4,D4}:1.63537506329;NFY{A,B,C}:1.59149270321;NKX2-3_NKX2-5:1.58792111239;E2F1..5:1.52684168045;NRF1:1.3753150316;NKX3-1:1.34059693162;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.32624644011;ZNF384:1.2095071455;PITX1..3:1.20271536682;ZNF143:1.17966996568;POU1F1:1.17778368796;PRRX1,2:1.09385797379;HIC1:1.08892499643;TOPORS:1.03092838818;EVI1:1.01097659789;EN1,2:1.00742457964;NFIX:0.972374942907;NKX6-1,2:0.968265473944;BREu{core}:0.938339873335;YY1:0.899682378467;GFI1:0.861869750318;CDC5L:0.788583213401;MEF2{A,B,C,D}:0.774645394712;RXR{A,B,G}:0.77330885815;PAX8:0.754509997334;SOX17:0.743772641805;NKX2-1,4:0.73549613734;FOXQ1:0.728222681513;IKZF2:0.727151044681;HIF1A:0.711209255189;PAX6:0.695058448762;PAX3,7:0.680968263199;FOXD3:0.67984146901;CUX2:0.672975236211;HES1:0.653863009287;MZF1:0.628806908873;T:0.576098790214;PAX1,9:0.566936470776;NR1H4:0.555955401983;PAX4:0.552787649793;PAX2:0.523328669091;MYB:0.517014026961;ZFP161:0.511782631308;FOXM1:0.502196647674;TFAP2B:0.477166298001;RREB1:0.455530948378;AIRE:0.452118800326;ZNF423:0.448463120228;FOXA2:0.435984968897;SOX{8,9,10}:0.408954208165;ATF4:0.405997098471;SP1:0.396419255216;PBX1:0.394849321674;LHX3,4:0.391959174708;XCPE1{core}:0.388009822123;ZBTB16:0.385702323615;STAT5{A,B}:0.3826276238;CDX1,2,4:0.373895080199;NFE2L2:0.373784615645;TEF:0.370197603629;TEAD1:0.366614791962;AHR_ARNT_ARNT2:0.362517816927;FOXP1:0.361302811122;NR3C1:0.348588782154;POU3F1..4:0.314760916496;UFEwm:0.303996537454;ELK1,4_GABP{A,B1}:0.30310082923;NR5A1,2:0.302962748798;TGIF1:0.277426404623;NANOG:0.276690802098;POU6F1:0.254360179761;PATZ1:0.251351329059;LEF1_TCF7_TCF7L1,2:0.243785999939;EGR1..3:0.198420927826;PRDM1:0.192616196806;NR6A1:0.190630432021;GTF2I:0.189542199632;ONECUT1,2:0.18663055944;ZIC1..3:0.186217168203;ESR1:0.167519114696;KLF4:0.162543737955;ATF6:0.156330187004;JUN:0.145483329583;FOX{F1,F2,J1}:0.127049447291;RUNX1..3:0.116632158526;SREBF1,2:0.114687441601;STAT1,3:0.100194229964;MYBL2:0.0955178803421;GATA4:0.0756370600894;ZBTB6:0.0649386532856;ATF5_CREB3:0.0391913874369;CREB1:0.0170768887022;NFE2L1:0.00881544892719;OCT4_SOX2{dimer}:-0.00222430644259;MED-1{core}:-0.0191878841013;TBX4,5:-0.0263206906881;MTE{core}:-0.0322340085668;HOX{A5,B5}:-0.035462173424;GTF2A1,2:-0.048043655742;IKZF1:-0.0597883433338;ARID5B:-0.0616627365095;DBP:-0.0658243752017;FOXP3:-0.0690026415995;FOXN1:-0.0824887675871;RBPJ:-0.0899549926312;HNF1A:-0.100009552996;MYFfamily:-0.106097904704;XBP1:-0.111152623675;RFX1:-0.117728018216;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.131146841899;ESRRA:-0.134057550846;GFI1B:-0.142566574794;NFE2:-0.149557398446;MAZ:-0.149602927613;TFAP4:-0.156859125014;ALX4:-0.170449065604;GZF1:-0.174503961031;EBF1:-0.174904538908;HNF4A_NR2F1,2:-0.186254107878;FOXL1:-0.188243834325;BACH2:-0.20937490508;REST:-0.231874870267;CRX:-0.232483979801;bHLH_family:-0.243604141438;GLI1..3:-0.25001179718;RFX2..5_RFXANK_RFXAP:-0.251212190166;POU5F1:-0.252662923945;AR:-0.253557370791;FOSL2:-0.25914869082;IRF7:-0.26501547727;FOX{I1,J2}:-0.269469045817;RORA:-0.27364469387;GCM1,2:-0.286776307585;FOS_FOS{B,L1}_JUN{B,D}:-0.29695576459;DMAP1_NCOR{1,2}_SMARC:-0.297622434664;SOX5:-0.317105082548;NKX3-2:-0.317966003168;GATA6:-0.324678985752;ZNF238:-0.335830355222;TFCP2:-0.338932359204;ADNP_IRX_SIX_ZHX:-0.358987514919;HLF:-0.372716919453;TLX1..3_NFIC{dimer}:-0.374701937201;TFAP2{A,C}:-0.378815608946;HOXA9_MEIS1:-0.390481382785;SOX2:-0.416625805828;NHLH1,2:-0.438955543125;ELF1,2,4:-0.445177084925;SMAD1..7,9:-0.4597195042;RXRA_VDR{dimer}:-0.468785979958;NFIL3:-0.476457314082;TP53:-0.489444098372;NFKB1_REL_RELA:-0.49608558489;PAX5:-0.502853326236;SRF:-0.503967982841;MTF1:-0.520002021062;MYOD1:-0.527148276108;ZNF148:-0.528019029815;TAL1_TCF{3,4,12}:-0.52862483224;IRF1,2:-0.535958409356;SNAI1..3:-0.543362110545;SPIB:-0.549783666409;MAFB:-0.557412843889;SPI1:-0.570350067031;BPTF:-0.587047182847;SPZ1:-0.61447061436;LMO2:-0.653079078502;ZEB1:-0.653748487161;HAND1,2:-0.668497142314;POU2F1..3:-0.670762286279;ATF2:-0.705760257722;NKX2-2,8:-0.741962221432;ALX1:-0.751608902648;HMGA1,2:-0.770391221143;ETS1,2:-0.779958781901;NANOG{mouse}:-0.817700339313;PPARG:-0.819028518297;HMX1:-0.85176513836;FOX{D1,D2}:-0.86349801592;CEBPA,B_DDIT3:-0.876610061171;HOX{A6,A7,B6,B7}:-0.91385263909;STAT2,4,6:-0.955940557821;HBP1_HMGB_SSRP1_UBTF:-1.05558553167;FOXO1,3,4:-1.22625889201;HSF1,2:-1.2319651436;TBP:-1.25287166499;NFATC1..3:-1.26722244612;EP300:-1.33588564296;TLX2:-1.37007261095 | ||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:12760-136B6;search_select_hide=table117:FF:12760-136B6 | |||
}} | }} | ||
Latest revision as of 18:44, 4 June 2020
| Name: | Saos-2 osteosarcoma treated with ascorbic acid and BGP to induce calcification |
|---|---|
| Species: | Human (Homo sapiens) |
| Library ID: | CNhs12859 |
| Sample type: | time courses |
| Genomic View: | UCSC |
| RefEX: | Specific genes |
| CAGEd-oPOSSUM: | link |
| ZENBU report : | link |
| Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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| CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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| Download raw sequence, BAM & CTSS | ||||||||||||||
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| RNA-Seq Accession numbers | ||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12859
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12859
| Novel motif | Logo | P-value |
|---|---|---|
| 1 | 1 | 0.325 |
| 10 | 10 | 0.897 |
| 100 | 100 | 0.529 |
| 101 | 101 | 0.55 |
| 102 | 102 | 0.521 |
| 103 | 103 | 0.0305 |
| 104 | 104 | 0.647 |
| 105 | 105 | 0.219 |
| 106 | 106 | 6.49749e-4 |
| 107 | 107 | 0.0406 |
| 108 | 108 | 0.957 |
| 109 | 109 | 0.14 |
| 11 | 11 | 0.114 |
| 110 | 110 | 0.325 |
| 111 | 111 | 0.274 |
| 112 | 112 | 0.072 |
| 113 | 113 | 0.249 |
| 114 | 114 | 0.0272 |
| 115 | 115 | 0.81 |
| 116 | 116 | 0.916 |
| 117 | 117 | 0.674 |
| 118 | 118 | 0.43 |
| 119 | 119 | 0.0549 |
| 12 | 12 | 0.933 |
| 120 | 120 | 0.974 |
| 121 | 121 | 0.605 |
| 122 | 122 | 0.523 |
| 123 | 123 | 0.152 |
| 124 | 124 | 0.177 |
| 125 | 125 | 0.0938 |
| 126 | 126 | 0.274 |
| 127 | 127 | 0.744 |
| 128 | 128 | 0.00775 |
| 129 | 129 | 0.248 |
| 13 | 13 | 0.419 |
| 130 | 130 | 0.0548 |
| 131 | 131 | 0.243 |
| 132 | 132 | 0.22 |
| 133 | 133 | 0.301 |
| 134 | 134 | 0.793 |
| 135 | 135 | 0.119 |
| 136 | 136 | 0.392 |
| 137 | 137 | 0.183 |
| 138 | 138 | 0.869 |
| 139 | 139 | 0.00134 |
| 14 | 14 | 0.308 |
| 140 | 140 | 0.554 |
| 141 | 141 | 0.648 |
| 142 | 142 | 0.843 |
| 143 | 143 | 0.0132 |
| 144 | 144 | 0.656 |
| 145 | 145 | 0.067 |
| 146 | 146 | 0.266 |
| 147 | 147 | 0.907 |
| 148 | 148 | 0.111 |
| 149 | 149 | 0.097 |
| 15 | 15 | 0.318 |
| 150 | 150 | 0.727 |
| 151 | 151 | 0.152 |
| 152 | 152 | 0.0354 |
| 153 | 153 | 0.147 |
| 154 | 154 | 0.692 |
| 155 | 155 | 0.441 |
| 156 | 156 | 0.594 |
| 157 | 157 | 0.418 |
| 158 | 158 | 0.454 |
| 159 | 159 | 0.623 |
| 16 | 16 | 0.333 |
| 160 | 160 | 0.439 |
| 161 | 161 | 0.716 |
| 162 | 162 | 0.872 |
| 163 | 163 | 0.856 |
| 164 | 164 | 0.684 |
| 165 | 165 | 0.221 |
| 166 | 166 | 0.536 |
| 167 | 167 | 0.186 |
| 168 | 168 | 0.163 |
| 169 | 169 | 0.0306 |
| 17 | 17 | 0.214 |
| 18 | 18 | 0.192 |
| 19 | 19 | 0.162 |
| 2 | 2 | 0.286 |
| 20 | 20 | 0.291 |
| 21 | 21 | 0.993 |
| 22 | 22 | 0.199 |
| 23 | 23 | 0.0185 |
| 24 | 24 | 0.965 |
| 25 | 25 | 0.81 |
| 26 | 26 | 0.662 |
| 27 | 27 | 0.0442 |
| 28 | 28 | 0.963 |
| 29 | 29 | 0.668 |
| 3 | 3 | 0.0784 |
| 30 | 30 | 0.467 |
| 31 | 31 | 0.621 |
| 32 | 32 | 0.412 |
| 33 | 33 | 0.424 |
| 34 | 34 | 0.357 |
| 35 | 35 | 0.257 |
| 36 | 36 | 0.208 |
| 37 | 37 | 0.125 |
| 38 | 38 | 0.284 |
| 39 | 39 | 0.208 |
| 4 | 4 | 0.71 |
| 40 | 40 | 0.313 |
| 41 | 41 | 0.201 |
| 42 | 42 | 0.181 |
| 43 | 43 | 0.139 |
| 44 | 44 | 0.255 |
| 45 | 45 | 0.121 |
| 46 | 46 | 0.231 |
| 47 | 47 | 0.268 |
| 48 | 48 | 0.449 |
| 49 | 49 | 0.158 |
| 5 | 5 | 0.256 |
| 50 | 50 | 0.368 |
| 51 | 51 | 0.619 |
| 52 | 52 | 0.215 |
| 53 | 53 | 0.43 |
| 54 | 54 | 0.373 |
| 55 | 55 | 0.0632 |
| 56 | 56 | 0.419 |
| 57 | 57 | 0.908 |
| 58 | 58 | 0.13 |
| 59 | 59 | 0.304 |
| 6 | 6 | 0.661 |
| 60 | 60 | 0.0404 |
| 61 | 61 | 0.989 |
| 62 | 62 | 0.0758 |
| 63 | 63 | 0.142 |
| 64 | 64 | 0.491 |
| 65 | 65 | 0.0316 |
| 66 | 66 | 0.233 |
| 67 | 67 | 0.901 |
| 68 | 68 | 0.706 |
| 69 | 69 | 0.975 |
| 7 | 7 | 0.538 |
| 70 | 70 | 0.00903 |
| 71 | 71 | 0.251 |
| 72 | 72 | 0.0683 |
| 73 | 73 | 0.0748 |
| 74 | 74 | 0.213 |
| 75 | 75 | 0.539 |
| 76 | 76 | 0.462 |
| 77 | 77 | 0.137 |
| 78 | 78 | 0.564 |
| 79 | 79 | 0.0752 |
| 8 | 8 | 0.39 |
| 80 | 80 | 0.0582 |
| 81 | 81 | 0.428 |
| 82 | 82 | 0.0405 |
| 83 | 83 | 0.356 |
| 84 | 84 | 0.56 |
| 85 | 85 | 0.00242 |
| 86 | 86 | 0.417 |
| 87 | 87 | 0.907 |
| 88 | 88 | 0.274 |
| 89 | 89 | 0.0282 |
| 9 | 9 | 0.228 |
| 90 | 90 | 0.295 |
| 91 | 91 | 0.484 |
| 92 | 92 | 0.0831 |
| 93 | 93 | 0.525 |
| 94 | 94 | 0.0407 |
| 95 | 95 | 0.38 |
| 96 | 96 | 0.216 |
| 97 | 97 | 0.647 |
| 98 | 98 | 0.292 |
| 99 | 99 | 0.485 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs12859
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000593 human Saos2 osteosarcoma cell line 0min after induction of calcification with ascorbate and BPG sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000055 (non-terminally differentiated cell)
0000003 (native cell)
0000548 (animal cell)
0002320 (connective tissue cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
0000062 (osteoblast)
UBERON: Anatomy
0000468 (multi-cellular organism)
0001474 (bone element)
0002384 (connective tissue)
0000479 (tissue)
0000062 (organ)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0004765 (skeletal element)
0002204 (musculoskeletal system)
0001434 (skeletal system)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0000350 (experimentally modified sample)
0000344 (0 minute sample)
0000332 (calcification induced with ascorbate and BPG sample)
0100971 (SAOS-2 cell sample)
0100385 (bone cancer cell line sample)
0100407 (osteosarcoma cell line sample)
0000593 (human Saos2 osteosarcoma cell line 0min after induction of calcification with ascorbate and BPG sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)
CL:0000335 (mesenchyme condensation cell)
