FF:12858-137D5: Difference between revisions
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{{f5samples | {{f5samples | ||
|ancestors_in_anatomy_facet=UBERON: | |DRA_sample_Accession=CAGE@SAMD00005731 | ||
|ancestors_in_cell_lineage_facet=CL:0000000 | |DRA_sample_Accession_RNASeq=sRNA-Seq@SAMD00005731 | ||
|accession_numbers=CAGE;DRX008602;DRR009474;DRZ000899;DRZ002284;DRZ012249;DRZ013634 | |||
|accession_numbers_RNASeq=sRNA-Seq;DRX037314;DRR041680;DRZ007322 | |||
|ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0001474,UBERON:0002384,UBERON:0000479,UBERON:0000062,UBERON:0000061,UBERON:0000465,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0004765,UBERON:0002204,UBERON:0001434 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000055,CL:0000003,CL:0000548,CL:0002320,CL:0002371,CL:0000255,CL:0000062 | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0000350,FF:0000344,FF:0000332,FF:0100971,FF:0100385,FF:0100407,FF:0000593 | |||
|comment=A3 T0 | |comment=A3 T0 | ||
|created_by= | |created_by= | ||
|creation_date= | |creation_date= | ||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |def= | ||
|donor= | |||
|fonse_cell_line=FF:0100385 | |fonse_cell_line=FF:0100385 | ||
|fonse_cell_line_closure=FF:0100385 | |fonse_cell_line_closure=FF:0100385 | ||
| Line 35: | Line 44: | ||
|fonse_treatment_closure=EFO:0000369,FF:0000332,FF:0000593,FF:12858-137D5 | |fonse_treatment_closure=EFO:0000369,FF:0000332,FF:0000593,FF:12858-137D5 | ||
|has_quality= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.timecourse.hCAGE/Saos-2%2520osteosarcoma%2520treated%2520with%2520ascorbic%2520acid%2520and%2520BGP%2520to%2520induce%2520calcification%252c%252000hr00min%252c%2520biol_rep3%2520%2528A3%2520T0%2529.CNhs12952.12858-137D5.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.timecourse.hCAGE/Saos-2%2520osteosarcoma%2520treated%2520with%2520ascorbic%2520acid%2520and%2520BGP%2520to%2520induce%2520calcification%252c%252000hr00min%252c%2520biol_rep3%2520%2528A3%2520T0%2529.CNhs12952.12858-137D5.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.timecourse.hCAGE/Saos-2%2520osteosarcoma%2520treated%2520with%2520ascorbic%2520acid%2520and%2520BGP%2520to%2520induce%2520calcification%252c%252000hr00min%252c%2520biol_rep3%2520%2528A3%2520T0%2529.CNhs12952.12858-137D5.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.timecourse.hCAGE/Saos-2%2520osteosarcoma%2520treated%2520with%2520ascorbic%2520acid%2520and%2520BGP%2520to%2520induce%2520calcification%252c%252000hr00min%252c%2520biol_rep3%2520%2528A3%2520T0%2529.CNhs12952.12858-137D5.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.timecourse.hCAGE/Saos-2%2520osteosarcoma%2520treated%2520with%2520ascorbic%2520acid%2520and%2520BGP%2520to%2520induce%2520calcification%252c%252000hr00min%252c%2520biol_rep3%2520%2528A3%2520T0%2529.CNhs12952.12858-137D5.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:12858-137D5 | |id=FF:12858-137D5 | ||
|is_a=EFO:0002091;;FF: | |is_a=EFO:0002091;;FF:0000593 | ||
|name=Saos-2 osteosarcoma treated with ascorbic acid and BGP to induce calcification | |is_obsolete= | ||
|library_id=CNhs12952 | |||
|library_id_phase_based=2:CNhs12952 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;12858 | |||
|microRNAs_nonnovel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer/#/human#srna;sample;SRhi10065.GTTTCG.12858 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;12858 | |||
|microRNAs_novel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer_novel/#/human#srna;sample;SRhi10065.GTTTCG.12858 | |||
|name=Saos-2 osteosarcoma treated with ascorbic acid and BGP to induce calcification | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |profile_cagescan=,,, | ||
|profile_hcage=CNhs12952,LSID980,release012,COMPLETED | |profile_hcage=CNhs12952,LSID980,release012,COMPLETED | ||
|profile_rnaseq= | |profile_rnaseq= | ||
|profile_srnaseq=,,, | |profile_srnaseq=,,, | ||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
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| |||
|rna_box=137 | |rna_box=137 | ||
|rna_catalog_number= | |rna_catalog_number= | ||
| Line 55: | Line 81: | ||
|rna_sample_type= | |rna_sample_type= | ||
|rna_tube_id=137D5 | |rna_tube_id=137D5 | ||
|rna_weight_ug=5. | |rna_weight_ug=5.3 | ||
|rnaseq_library_id=SRhi10065.GTTTCG | |||
|sample_age= | |sample_age= | ||
|sample_category=time courses | |||
|sample_cell_catalog= | |sample_cell_catalog= | ||
|sample_cell_line=Saos-2 | |sample_cell_line=Saos-2 | ||
| Line 69: | Line 97: | ||
|sample_ethnicity= | |sample_ethnicity= | ||
|sample_experimental_condition=Saos-2 osteosarcoma treated with ascorbic acid and BGP to induce calcification | |sample_experimental_condition=Saos-2 osteosarcoma treated with ascorbic acid and BGP to induce calcification | ||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;2.99725714113972e-284!GO:0043226;organelle;3.25508452983611e-244!GO:0043229;intracellular organelle;1.18608385463022e-243!GO:0043231;intracellular membrane-bound organelle;1.61840221414748e-240!GO:0043227;membrane-bound organelle;2.3699517861528e-240!GO:0044422;organelle part;3.01382597196463e-168!GO:0005737;cytoplasm;9.40701335869204e-168!GO:0044446;intracellular organelle part;7.08342068451035e-167!GO:0005634;nucleus;7.20649772166886e-125!GO:0032991;macromolecular complex;1.98986666392916e-117!GO:0044444;cytoplasmic part;2.76366648527656e-114!GO:0044238;primary metabolic process;3.10036025610477e-108!GO:0044237;cellular metabolic process;2.52537891567828e-105!GO:0043170;macromolecule metabolic process;6.14784637258393e-104!GO:0044428;nuclear part;7.20801054624836e-94!GO:0030529;ribonucleoprotein complex;6.2149451132636e-88!GO:0043233;organelle lumen;3.94234360093879e-83!GO:0031974;membrane-enclosed lumen;3.94234360093879e-83!GO:0003723;RNA binding;4.47224961719245e-80!GO:0005515;protein binding;1.67996690380534e-75!GO:0043283;biopolymer metabolic process;8.15219028756629e-74!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;9.81578102977853e-68!GO:0016043;cellular component organization and biogenesis;1.15270952455316e-62!GO:0043234;protein complex;1.69048423340126e-62!GO:0005739;mitochondrion;2.05195411958006e-60!GO:0010467;gene expression;2.76410096194381e-60!GO:0006396;RNA processing;8.29252557379442e-59!GO:0031981;nuclear lumen;3.45293617928058e-55!GO:0006259;DNA metabolic process;1.19216695677488e-48!GO:0005840;ribosome;4.2385147819088e-48!GO:0031090;organelle membrane;6.95915308037827e-48!GO:0003676;nucleic acid binding;1.72700086184275e-46!GO:0043228;non-membrane-bound organelle;1.90555835384493e-46!GO:0043232;intracellular non-membrane-bound organelle;1.90555835384493e-46!GO:0016071;mRNA metabolic process;5.0433967090271e-46!GO:0006412;translation;1.18006136316311e-45!GO:0006996;organelle organization and biogenesis;3.62653202344691e-44!GO:0031967;organelle envelope;4.29854289028051e-44!GO:0033036;macromolecule localization;7.44095170452104e-44!GO:0031975;envelope;8.1545807897625e-44!GO:0044429;mitochondrial part;1.88496102857219e-43!GO:0015031;protein transport;1.56783810164385e-42!GO:0003735;structural constituent of ribosome;1.76243791845308e-41!GO:0008380;RNA splicing;2.0242595900294e-41!GO:0019538;protein metabolic process;2.29637768890313e-41!GO:0046907;intracellular transport;8.36212112566268e-41!GO:0006397;mRNA processing;3.08094857782224e-40!GO:0008104;protein localization;4.63092198901711e-39!GO:0007049;cell cycle;9.23634076178381e-39!GO:0065003;macromolecular complex assembly;7.25644324178245e-38!GO:0045184;establishment of protein localization;8.76355147028596e-38!GO:0005654;nucleoplasm;3.33641104862907e-36!GO:0044260;cellular macromolecule metabolic process;5.38951784620627e-36!GO:0044267;cellular protein metabolic process;2.66683977759524e-35!GO:0009058;biosynthetic process;3.18955418248467e-35!GO:0044249;cellular biosynthetic process;9.41922509485611e-35!GO:0016070;RNA metabolic process;2.3153906259033e-34!GO:0033279;ribosomal subunit;2.9786211156969e-34!GO:0009059;macromolecule biosynthetic process;2.99155913133888e-33!GO:0022607;cellular component assembly;5.74412804216842e-33!GO:0006886;intracellular protein transport;1.37426710576346e-32!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.92460813545669e-32!GO:0005829;cytosol;1.40772401272026e-31!GO:0000166;nucleotide binding;1.92694853957741e-31!GO:0005681;spliceosome;7.6281928489764e-30!GO:0005694;chromosome;1.9602005939196e-29!GO:0044451;nucleoplasm part;1.98642007035451e-28!GO:0006974;response to DNA damage stimulus;2.15226823105417e-28!GO:0005740;mitochondrial envelope;2.18030380205022e-28!GO:0022402;cell cycle process;5.29880798877471e-28!GO:0031966;mitochondrial membrane;1.77473906904957e-27!GO:0019866;organelle inner membrane;5.87832079398815e-27!GO:0000278;mitotic cell cycle;9.30358075960122e-27!GO:0051649;establishment of cellular localization;2.01488200986246e-26!GO:0051641;cellular localization;3.89734239525921e-26!GO:0006281;DNA repair;1.5418018197982e-25!GO:0044427;chromosomal part;5.11876633142272e-25!GO:0005830;cytosolic ribosome (sensu Eukaryota);5.88084894214547e-25!GO:0016462;pyrophosphatase activity;8.11396580853621e-25!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;8.75276259081467e-25!GO:0016817;hydrolase activity, acting on acid anhydrides;1.086719827277e-24!GO:0005743;mitochondrial inner membrane;1.88026802910278e-24!GO:0017111;nucleoside-triphosphatase activity;3.84879449627309e-24!GO:0051276;chromosome organization and biogenesis;4.643325568808e-23!GO:0032553;ribonucleotide binding;1.13782173234132e-22!GO:0032555;purine ribonucleotide binding;1.13782173234132e-22!GO:0022403;cell cycle phase;1.38120098469195e-22!GO:0006512;ubiquitin cycle;2.00163528315767e-22!GO:0051301;cell division;4.46252275638339e-22!GO:0000087;M phase of mitotic cell cycle;6.93658760077009e-22!GO:0016874;ligase activity;1.3237645867102e-21!GO:0007067;mitosis;1.41935221340264e-21!GO:0017076;purine nucleotide binding;1.58177172063981e-21!GO:0006119;oxidative phosphorylation;6.67635739290736e-21!GO:0006260;DNA replication;9.30464647219099e-21!GO:0051603;proteolysis involved in cellular protein catabolic process;1.92986196020288e-20!GO:0005524;ATP binding;1.97301695230592e-20!GO:0032559;adenyl ribonucleotide binding;2.77594066470715e-20!GO:0019941;modification-dependent protein catabolic process;3.57841525686326e-20!GO:0043632;modification-dependent macromolecule catabolic process;3.57841525686326e-20!GO:0044445;cytosolic part;5.78769482418147e-20!GO:0044455;mitochondrial membrane part;7.12168233622478e-20!GO:0006511;ubiquitin-dependent protein catabolic process;8.5868678250017e-20!GO:0044257;cellular protein catabolic process;8.81600458407071e-20!GO:0012505;endomembrane system;9.51167951086429e-20!GO:0000279;M phase;3.03935816855031e-19!GO:0044265;cellular macromolecule catabolic process;5.50910881555586e-19!GO:0030554;adenyl nucleotide binding;6.9466811158509e-19!GO:0009719;response to endogenous stimulus;2.06249831952348e-18!GO:0022618;protein-RNA complex assembly;2.19279537529652e-18!GO:0005730;nucleolus;2.19279537529652e-18!GO:0015935;small ribosomal subunit;2.54080499920824e-18!GO:0031980;mitochondrial lumen;3.73144270526144e-18!GO:0005759;mitochondrial matrix;3.73144270526144e-18!GO:0006457;protein folding;8.99539018314053e-18!GO:0006325;establishment and/or maintenance of chromatin architecture;1.13388723792195e-17!GO:0043285;biopolymer catabolic process;1.579721098671e-17!GO:0006323;DNA packaging;5.19221812306402e-17!GO:0015934;large ribosomal subunit;5.34997726047136e-17!GO:0031965;nuclear membrane;6.58807758228031e-17!GO:0006605;protein targeting;1.33766634026778e-16!GO:0008135;translation factor activity, nucleic acid binding;1.47270028551602e-16!GO:0000502;proteasome complex (sensu Eukaryota);1.90795351859774e-16!GO:0048770;pigment granule;3.1418502746158e-16!GO:0042470;melanosome;3.1418502746158e-16!GO:0005635;nuclear envelope;3.33603624058421e-16!GO:0016887;ATPase activity;5.35420679632169e-16!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;6.0573494461394e-16!GO:0030163;protein catabolic process;7.8148942344954e-16!GO:0005746;mitochondrial respiratory chain;1.06296470698732e-15!GO:0009057;macromolecule catabolic process;1.20319346836483e-15!GO:0000398;nuclear mRNA splicing, via spliceosome;1.53149634795135e-15!GO:0000375;RNA splicing, via transesterification reactions;1.53149634795135e-15!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;1.53149634795135e-15!GO:0008134;transcription factor binding;1.66946562362919e-15!GO:0042623;ATPase activity, coupled;5.37062818006577e-15!GO:0044453;nuclear membrane part;5.86382975742855e-15!GO:0042254;ribosome biogenesis and assembly;6.24989163844308e-15!GO:0044248;cellular catabolic process;1.21936512552021e-14!GO:0050136;NADH dehydrogenase (quinone) activity;1.29401872220334e-14!GO:0003954;NADH dehydrogenase activity;1.29401872220334e-14!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.29401872220334e-14!GO:0016604;nuclear body;1.64817556482087e-14!GO:0043412;biopolymer modification;1.81112635203172e-14!GO:0005783;endoplasmic reticulum;1.81744272251837e-14!GO:0004386;helicase activity;2.5688516812926e-14!GO:0006913;nucleocytoplasmic transport;3.86374968483391e-14!GO:0048193;Golgi vesicle transport;6.09387221912797e-14!GO:0015630;microtubule cytoskeleton;6.98002209938395e-14!GO:0051169;nuclear transport;1.18490636449706e-13!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.42325915633119e-13!GO:0051726;regulation of cell cycle;2.22940838377153e-13!GO:0000074;regulation of progression through cell cycle;2.49720176375507e-13!GO:0044432;endoplasmic reticulum part;2.70333845087036e-13!GO:0005761;mitochondrial ribosome;2.72327056956279e-13!GO:0000313;organellar ribosome;2.72327056956279e-13!GO:0006333;chromatin assembly or disassembly;2.80578138640369e-13!GO:0050657;nucleic acid transport;4.47396499207864e-13!GO:0051236;establishment of RNA localization;4.47396499207864e-13!GO:0050658;RNA transport;4.47396499207864e-13!GO:0006403;RNA localization;5.07841784393835e-13!GO:0051186;cofactor metabolic process;6.363002436846e-13!GO:0065004;protein-DNA complex assembly;7.92643986244673e-13!GO:0000785;chromatin;1.15416075933007e-12!GO:0005643;nuclear pore;1.33508729877612e-12!GO:0042775;organelle ATP synthesis coupled electron transport;1.35624490921583e-12!GO:0042773;ATP synthesis coupled electron transport;1.35624490921583e-12!GO:0030964;NADH dehydrogenase complex (quinone);1.70888397866992e-12!GO:0045271;respiratory chain complex I;1.70888397866992e-12!GO:0005747;mitochondrial respiratory chain complex I;1.70888397866992e-12!GO:0005794;Golgi apparatus;1.99801157283847e-12!GO:0006464;protein modification process;2.00875721095767e-12!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;3.1919545573205e-12!GO:0051082;unfolded protein binding;3.26402899991817e-12!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;4.32192073829192e-12!GO:0003743;translation initiation factor activity;4.64930158184954e-12!GO:0016192;vesicle-mediated transport;4.67150034832753e-12!GO:0008026;ATP-dependent helicase activity;6.02173247487759e-12!GO:0000775;chromosome, pericentric region;6.94091435600964e-12!GO:0065002;intracellular protein transport across a membrane;7.54536493298291e-12!GO:0006399;tRNA metabolic process;7.65364554268749e-12!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);7.69662990249249e-12!GO:0006261;DNA-dependent DNA replication;7.8615232569915e-12!GO:0043687;post-translational protein modification;1.00593196289702e-11!GO:0016607;nuclear speck;1.09043733140851e-11!GO:0008639;small protein conjugating enzyme activity;1.4157512003678e-11!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.50595163974576e-11!GO:0050794;regulation of cellular process;1.99609468385457e-11!GO:0016568;chromatin modification;2.12279232655942e-11!GO:0004842;ubiquitin-protein ligase activity;4.38978644108164e-11!GO:0006366;transcription from RNA polymerase II promoter;6.06224874023538e-11!GO:0006413;translational initiation;7.36454707657783e-11!GO:0016879;ligase activity, forming carbon-nitrogen bonds;7.74104704643727e-11!GO:0008565;protein transporter activity;7.84323841209711e-11!GO:0051028;mRNA transport;8.27550677592209e-11!GO:0006461;protein complex assembly;8.5998189131898e-11!GO:0006732;coenzyme metabolic process;1.53400279044023e-10!GO:0006364;rRNA processing;1.58899468460182e-10!GO:0019787;small conjugating protein ligase activity;1.85405496214076e-10!GO:0019222;regulation of metabolic process;2.47432173198176e-10!GO:0009259;ribonucleotide metabolic process;3.8279178182853e-10!GO:0005819;spindle;4.25867976414393e-10!GO:0017038;protein import;4.44431215487142e-10!GO:0016072;rRNA metabolic process;4.94926384067422e-10!GO:0046930;pore complex;5.2758450687352e-10!GO:0006163;purine nucleotide metabolic process;6.39855382908703e-10!GO:0006446;regulation of translational initiation;7.11803735410259e-10!GO:0042175;nuclear envelope-endoplasmic reticulum network;8.03781825953433e-10!GO:0016881;acid-amino acid ligase activity;1.31552087858084e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.46646841573094e-09!GO:0006334;nucleosome assembly;2.15181916824592e-09!GO:0005789;endoplasmic reticulum membrane;2.46006481252235e-09!GO:0003697;single-stranded DNA binding;2.48715485840634e-09!GO:0043566;structure-specific DNA binding;3.03149276010425e-09!GO:0031497;chromatin assembly;4.24523553085324e-09!GO:0030532;small nuclear ribonucleoprotein complex;4.75574410566127e-09!GO:0009150;purine ribonucleotide metabolic process;5.23489268504334e-09!GO:0003712;transcription cofactor activity;5.25319968606664e-09!GO:0005813;centrosome;6.69987555745201e-09!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;7.84485135389296e-09!GO:0004812;aminoacyl-tRNA ligase activity;7.84485135389296e-09!GO:0016875;ligase activity, forming carbon-oxygen bonds;7.84485135389296e-09!GO:0009055;electron carrier activity;8.89830511995377e-09!GO:0048475;coated membrane;9.65919277775763e-09!GO:0030117;membrane coat;9.65919277775763e-09!GO:0006164;purine nucleotide biosynthetic process;1.04216641399372e-08!GO:0009141;nucleoside triphosphate metabolic process;1.23002907997172e-08!GO:0000075;cell cycle checkpoint;1.32457303871315e-08!GO:0051329;interphase of mitotic cell cycle;1.35056358719259e-08!GO:0009260;ribonucleotide biosynthetic process;1.39417676916638e-08!GO:0009199;ribonucleoside triphosphate metabolic process;1.57903941973225e-08!GO:0016779;nucleotidyltransferase activity;1.64875313751824e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;1.64875313751824e-08!GO:0005815;microtubule organizing center;1.97739550000429e-08!GO:0005667;transcription factor complex;2.06068139637399e-08!GO:0016740;transferase activity;2.09249563065385e-08!GO:0032446;protein modification by small protein conjugation;2.16019033757234e-08!GO:0043038;amino acid activation;2.18238518290223e-08!GO:0006418;tRNA aminoacylation for protein translation;2.18238518290223e-08!GO:0043039;tRNA aminoacylation;2.18238518290223e-08!GO:0005793;ER-Golgi intermediate compartment;2.48818017057512e-08!GO:0007051;spindle organization and biogenesis;2.87775880200662e-08!GO:0016567;protein ubiquitination;3.05182155984715e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;3.61730098151812e-08!GO:0009144;purine nucleoside triphosphate metabolic process;3.61730098151812e-08!GO:0006350;transcription;3.63826230858734e-08!GO:0031323;regulation of cellular metabolic process;5.02233039536425e-08!GO:0046034;ATP metabolic process;5.39521433150361e-08!GO:0051325;interphase;5.59214019679558e-08!GO:0009060;aerobic respiration;6.5429947426578e-08!GO:0009152;purine ribonucleotide biosynthetic process;8.4726876827238e-08!GO:0015986;ATP synthesis coupled proton transport;8.57927054580055e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;8.57927054580055e-08!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;8.73214981362071e-08!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.12189807450612e-07!GO:0051170;nuclear import;1.14419388835795e-07!GO:0009056;catabolic process;1.23283994861455e-07!GO:0006888;ER to Golgi vesicle-mediated transport;1.27817482031622e-07!GO:0050789;regulation of biological process;1.28257553728856e-07!GO:0030120;vesicle coat;1.89805752370765e-07!GO:0030662;coated vesicle membrane;1.89805752370765e-07!GO:0006606;protein import into nucleus;2.46849395941537e-07!GO:0003682;chromatin binding;2.54047802608165e-07!GO:0005657;replication fork;2.86209344010588e-07!GO:0045333;cellular respiration;3.05012547418192e-07!GO:0000151;ubiquitin ligase complex;3.07695189097572e-07!GO:0009142;nucleoside triphosphate biosynthetic process;3.57516640395782e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;3.57516640395782e-07!GO:0000245;spliceosome assembly;3.80038480622234e-07!GO:0007005;mitochondrion organization and biogenesis;5.53507176044425e-07!GO:0019829;cation-transporting ATPase activity;5.66405467705192e-07!GO:0044431;Golgi apparatus part;6.00392637610204e-07!GO:0008094;DNA-dependent ATPase activity;6.11070567259061e-07!GO:0015078;hydrogen ion transmembrane transporter activity;6.39357954576446e-07!GO:0031324;negative regulation of cellular metabolic process;6.9227422687528e-07!GO:0031202;RNA splicing factor activity, transesterification mechanism;7.38940196733257e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;8.12734507704501e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;8.12734507704501e-07!GO:0016772;transferase activity, transferring phosphorus-containing groups;8.4555601984876e-07!GO:0016469;proton-transporting two-sector ATPase complex;9.96514399154481e-07!GO:0006099;tricarboxylic acid cycle;9.96514399154481e-07!GO:0046356;acetyl-CoA catabolic process;9.96514399154481e-07!GO:0043623;cellular protein complex assembly;9.96514399154481e-07!GO:0005768;endosome;9.96514399154481e-07!GO:0012501;programmed cell death;1.08119700189787e-06!GO:0005798;Golgi-associated vesicle;1.09641826211104e-06!GO:0006754;ATP biosynthetic process;1.14084586914653e-06!GO:0006753;nucleoside phosphate metabolic process;1.14084586914653e-06!GO:0051188;cofactor biosynthetic process;1.3357694564188e-06!GO:0045786;negative regulation of progression through cell cycle;1.35663337087513e-06!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.38602270315967e-06!GO:0006915;apoptosis;1.41016674465476e-06!GO:0003677;DNA binding;1.62834555280896e-06!GO:0003924;GTPase activity;1.76248691761451e-06!GO:0007059;chromosome segregation;1.82308441604423e-06!GO:0032774;RNA biosynthetic process;1.93713568619756e-06!GO:0005839;proteasome core complex (sensu Eukaryota);2.02638495696499e-06!GO:0010468;regulation of gene expression;2.02882450074382e-06!GO:0006302;double-strand break repair;2.2154632643246e-06!GO:0045259;proton-transporting ATP synthase complex;2.48890576273151e-06!GO:0003899;DNA-directed RNA polymerase activity;2.49578842972063e-06!GO:0009117;nucleotide metabolic process;2.72647535658799e-06!GO:0004298;threonine endopeptidase activity;2.91940520098845e-06!GO:0006351;transcription, DNA-dependent;2.94218158698872e-06!GO:0006752;group transfer coenzyme metabolic process;3.15638789194272e-06!GO:0006084;acetyl-CoA metabolic process;3.7483906841456e-06!GO:0006793;phosphorus metabolic process;3.84968190091298e-06!GO:0006796;phosphate metabolic process;3.84968190091298e-06!GO:0048523;negative regulation of cellular process;4.17842242456177e-06!GO:0016363;nuclear matrix;4.18467612939141e-06!GO:0005788;endoplasmic reticulum lumen;4.37967655895832e-06!GO:0005874;microtubule;4.60746355609357e-06!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;4.73573966778414e-06!GO:0051168;nuclear export;5.38027212810625e-06!GO:0009109;coenzyme catabolic process;5.38180942711436e-06!GO:0051427;hormone receptor binding;6.49872168686845e-06!GO:0006613;cotranslational protein targeting to membrane;6.49872168686845e-06!GO:0008219;cell death;7.71698638359431e-06!GO:0016265;death;7.71698638359431e-06!GO:0003724;RNA helicase activity;7.78409185583751e-06!GO:0009892;negative regulation of metabolic process;8.40363113149842e-06!GO:0051052;regulation of DNA metabolic process;8.53671935240755e-06!GO:0009108;coenzyme biosynthetic process;8.99532740180407e-06!GO:0051246;regulation of protein metabolic process;9.50136831478101e-06!GO:0030867;rough endoplasmic reticulum membrane;9.73994091817309e-06!GO:0051187;cofactor catabolic process;1.0846174178811e-05!GO:0016310;phosphorylation;1.09559069435311e-05!GO:0008654;phospholipid biosynthetic process;1.10619730524894e-05!GO:0006310;DNA recombination;1.3939990204006e-05!GO:0000776;kinetochore;1.44224099923859e-05!GO:0035257;nuclear hormone receptor binding;1.5852715124287e-05!GO:0007010;cytoskeleton organization and biogenesis;2.22894039623276e-05!GO:0006357;regulation of transcription from RNA polymerase II promoter;2.67624692909177e-05!GO:0015077;monovalent inorganic cation transmembrane transporter activity;2.71962995273794e-05!GO:0005905;coated pit;2.7928665585385e-05!GO:0019899;enzyme binding;3.18587770175842e-05!GO:0006414;translational elongation;4.12073768664057e-05!GO:0007093;mitotic cell cycle checkpoint;4.2757061691785e-05!GO:0003713;transcription coactivator activity;4.35994947147839e-05!GO:0045449;regulation of transcription;4.66319953631609e-05!GO:0016853;isomerase activity;5.28580289570632e-05!GO:0015980;energy derivation by oxidation of organic compounds;6.03398002206623e-05!GO:0044452;nucleolar part;6.03398002206623e-05!GO:0016787;hydrolase activity;6.0810268240887e-05!GO:0016481;negative regulation of transcription;6.25131843084227e-05!GO:0005762;mitochondrial large ribosomal subunit;6.41700799731973e-05!GO:0000315;organellar large ribosomal subunit;6.41700799731973e-05!GO:0006383;transcription from RNA polymerase III promoter;6.56918190477818e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;6.75088649193412e-05!GO:0016563;transcription activator activity;7.18867452403713e-05!GO:0000139;Golgi membrane;7.63123585689314e-05!GO:0007088;regulation of mitosis;7.95030913716769e-05!GO:0043021;ribonucleoprotein binding;8.24475775606851e-05!GO:0043284;biopolymer biosynthetic process;8.24475775606851e-05!GO:0015631;tubulin binding;9.44075916230917e-05!GO:0008033;tRNA processing;9.53221250991299e-05!GO:0007052;mitotic spindle organization and biogenesis;9.54496189267969e-05!GO:0003690;double-stranded DNA binding;0.000104262739757296!GO:0003684;damaged DNA binding;0.000111195500669372!GO:0030118;clathrin coat;0.000111326697427369!GO:0000082;G1/S transition of mitotic cell cycle;0.000117356475669651!GO:0003678;DNA helicase activity;0.000123015575332592!GO:0000059;protein import into nucleus, docking;0.000125469736722616!GO:0048519;negative regulation of biological process;0.000146905797246941!GO:0044440;endosomal part;0.000189297141354905!GO:0010008;endosome membrane;0.000189297141354905!GO:0000228;nuclear chromosome;0.000201811342874469!GO:0031968;organelle outer membrane;0.000209700219099026!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.000214251112418835!GO:0031988;membrane-bound vesicle;0.000218122785905185!GO:0007017;microtubule-based process;0.000222610756590902!GO:0045454;cell redox homeostasis;0.000226427021062653!GO:0005791;rough endoplasmic reticulum;0.000243586793032126!GO:0008022;protein C-terminus binding;0.000246523443079576!GO:0005525;GTP binding;0.000246523443079576!GO:0003729;mRNA binding;0.000252734337250162!GO:0016023;cytoplasmic membrane-bound vesicle;0.000253394715387198!GO:0006355;regulation of transcription, DNA-dependent;0.000254160954592847!GO:0016859;cis-trans isomerase activity;0.000267539510407066!GO:0008186;RNA-dependent ATPase activity;0.000271076635264927!GO:0006352;transcription initiation;0.00028283574376272!GO:0006839;mitochondrial transport;0.000288813123016364!GO:0006612;protein targeting to membrane;0.000301848489993264!GO:0016564;transcription repressor activity;0.000307165168063016!GO:0000786;nucleosome;0.00031647033750926!GO:0006275;regulation of DNA replication;0.00032041633213126!GO:0003714;transcription corepressor activity;0.000350953316751619!GO:0019867;outer membrane;0.000351922698527977!GO:0000314;organellar small ribosomal subunit;0.000425130338109284!GO:0005763;mitochondrial small ribosomal subunit;0.000425130338109284!GO:0005770;late endosome;0.000456547020416971!GO:0046489;phosphoinositide biosynthetic process;0.000471668060282115!GO:0006338;chromatin remodeling;0.000480963515931544!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000481885782737492!GO:0005741;mitochondrial outer membrane;0.00050660194154246!GO:0046474;glycerophospholipid biosynthetic process;0.000514195567088455!GO:0008250;oligosaccharyl transferase complex;0.000533926866433662!GO:0005885;Arp2/3 protein complex;0.000534647208296387!GO:0000049;tRNA binding;0.0005419788577786!GO:0005769;early endosome;0.000544938754534796!GO:0031252;leading edge;0.000553202563318788!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000554573140654391!GO:0030658;transport vesicle membrane;0.000604721302649336!GO:0016126;sterol biosynthetic process;0.000639939961210181!GO:0031982;vesicle;0.000648656978963468!GO:0016741;transferase activity, transferring one-carbon groups;0.000676776283713974!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.000724770136204121!GO:0005684;U2-dependent spliceosome;0.000726094864400349!GO:0008092;cytoskeletal protein binding;0.000727219525919142!GO:0004576;oligosaccharyl transferase activity;0.000738009282852981!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000773179659973338!GO:0004004;ATP-dependent RNA helicase activity;0.000773627037395545!GO:0016790;thiolester hydrolase activity;0.000814257880600157!GO:0008168;methyltransferase activity;0.000836376552307269!GO:0007050;cell cycle arrest;0.000840603972753302!GO:0004527;exonuclease activity;0.000850563699247821!GO:0006402;mRNA catabolic process;0.000866319041290693!GO:0031072;heat shock protein binding;0.000869348596797222!GO:0019783;small conjugating protein-specific protease activity;0.000892351370312241!GO:0031124;mRNA 3'-end processing;0.000915043098835115!GO:0032508;DNA duplex unwinding;0.000915043098835115!GO:0032392;DNA geometric change;0.000915043098835115!GO:0031410;cytoplasmic vesicle;0.000918434141244101!GO:0051789;response to protein stimulus;0.000949848814469076!GO:0006986;response to unfolded protein;0.000949848814469076!GO:0033116;ER-Golgi intermediate compartment membrane;0.000960820952123134!GO:0004843;ubiquitin-specific protease activity;0.000967454121246949!GO:0048500;signal recognition particle;0.00106636769691794!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.00115892753935565!GO:0030660;Golgi-associated vesicle membrane;0.00117351823576537!GO:0005637;nuclear inner membrane;0.00119337135544764!GO:0000922;spindle pole;0.00120193907865915!GO:0004674;protein serine/threonine kinase activity;0.00120244205699154!GO:0005876;spindle microtubule;0.00120984442008623!GO:0042393;histone binding;0.00120984442008623!GO:0043596;nuclear replication fork;0.0012358260072639!GO:0006611;protein export from nucleus;0.00126482378452428!GO:0006626;protein targeting to mitochondrion;0.00127319905177113!GO:0003746;translation elongation factor activity;0.00133206210731359!GO:0030880;RNA polymerase complex;0.00136795154930212!GO:0032561;guanyl ribonucleotide binding;0.0014095501014108!GO:0019001;guanyl nucleotide binding;0.0014095501014108!GO:0009165;nucleotide biosynthetic process;0.00141200155729377!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00142742866811872!GO:0000819;sister chromatid segregation;0.00142890443321368!GO:0004221;ubiquitin thiolesterase activity;0.00144551465145583!GO:0006268;DNA unwinding during replication;0.00154768218541087!GO:0065007;biological regulation;0.00154926532214333!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00155357784943061!GO:0005048;signal sequence binding;0.00159952692781788!GO:0030133;transport vesicle;0.00161360673288306!GO:0000287;magnesium ion binding;0.00161360673288306!GO:0008312;7S RNA binding;0.00161695473527923!GO:0006405;RNA export from nucleus;0.00167635071421946!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00169209422848482!GO:0030176;integral to endoplasmic reticulum membrane;0.00169545613905837!GO:0006695;cholesterol biosynthetic process;0.00175131096112708!GO:0051087;chaperone binding;0.00176822970901162!GO:0016251;general RNA polymerase II transcription factor activity;0.0017913123213308!GO:0043681;protein import into mitochondrion;0.001792063562037!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00192224800636989!GO:0042981;regulation of apoptosis;0.00192836362018021!GO:0051539;4 iron, 4 sulfur cluster binding;0.00196650284075945!GO:0000070;mitotic sister chromatid segregation;0.00196660836231418!GO:0043067;regulation of programmed cell death;0.00196660836231418!GO:0048471;perinuclear region of cytoplasm;0.00199133122037104!GO:0006270;DNA replication initiation;0.00206983828305467!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00233471761102889!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00233471761102889!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00233471761102889!GO:0018196;peptidyl-asparagine modification;0.0023677961487129!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0023677961487129!GO:0009112;nucleobase metabolic process;0.00237274790247087!GO:0006144;purine base metabolic process;0.00243987918845635!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00260916201431542!GO:0046467;membrane lipid biosynthetic process;0.0029051808768741!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00296782214517274!GO:0000428;DNA-directed RNA polymerase complex;0.00296782214517274!GO:0008097;5S rRNA binding;0.00301333747761425!GO:0000910;cytokinesis;0.00303005930303388!GO:0035258;steroid hormone receptor binding;0.0030386075814817!GO:0030663;COPI coated vesicle membrane;0.00305828859097181!GO:0030126;COPI vesicle coat;0.00305828859097181!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.0030849888455091!GO:0015399;primary active transmembrane transporter activity;0.0030849888455091!GO:0006891;intra-Golgi vesicle-mediated transport;0.00314917145151467!GO:0043601;nuclear replisome;0.00314917145151467!GO:0030894;replisome;0.00314917145151467!GO:0046483;heterocycle metabolic process;0.0031768102416146!GO:0030521;androgen receptor signaling pathway;0.00329707519808828!GO:0043069;negative regulation of programmed cell death;0.00329841841078762!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00330112191099131!GO:0045047;protein targeting to ER;0.00330112191099131!GO:0031123;RNA 3'-end processing;0.00335311394157458!GO:0042802;identical protein binding;0.00358920846864109!GO:0007006;mitochondrial membrane organization and biogenesis;0.00363849350307081!GO:0030119;AP-type membrane coat adaptor complex;0.00368292776891888!GO:0006401;RNA catabolic process;0.00397518024415457!GO:0006284;base-excision repair;0.00406569765184006!GO:0005773;vacuole;0.00415071031766613!GO:0051287;NAD binding;0.00419427539100164!GO:0030384;phosphoinositide metabolic process;0.00426370523176104!GO:0030134;ER to Golgi transport vesicle;0.00427750716983943!GO:0048487;beta-tubulin binding;0.00447438313840336!GO:0030131;clathrin adaptor complex;0.00450637102786133!GO:0006378;mRNA polyadenylation;0.00455439413585174!GO:0030036;actin cytoskeleton organization and biogenesis;0.00455439413585174!GO:0043066;negative regulation of apoptosis;0.00457378704409387!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00471418308392811!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00471418308392811!GO:0051101;regulation of DNA binding;0.00472711858321531!GO:0009116;nucleoside metabolic process;0.00472711858321531!GO:0051252;regulation of RNA metabolic process;0.00472711858321531!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.00473051555143698!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.00473051555143698!GO:0016044;membrane organization and biogenesis;0.00473825328275174!GO:0004518;nuclease activity;0.00483781062904508!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00510642889884095!GO:0030132;clathrin coat of coated pit;0.00510652166205479!GO:0006892;post-Golgi vesicle-mediated transport;0.00529780192409895!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00541689677536303!GO:0046966;thyroid hormone receptor binding;0.00560286571875587!GO:0008017;microtubule binding;0.0056399705240874!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00566113917102543!GO:0006506;GPI anchor biosynthetic process;0.00570590039047339!GO:0003711;transcription elongation regulator activity;0.00571431409650024!GO:0003702;RNA polymerase II transcription factor activity;0.00577060706264274!GO:0006650;glycerophospholipid metabolic process;0.00596789627953497!GO:0006607;NLS-bearing substrate import into nucleus;0.0063102532546685!GO:0046112;nucleobase biosynthetic process;0.0063102532546685!GO:0019206;nucleoside kinase activity;0.00654664743177941!GO:0008361;regulation of cell size;0.00670444374070579!GO:0006818;hydrogen transport;0.00670444374070579!GO:0000792;heterochromatin;0.00670444374070579!GO:0015992;proton transport;0.00673092967032141!GO:0030518;steroid hormone receptor signaling pathway;0.00687214708155706!GO:0006505;GPI anchor metabolic process;0.0069118467379229!GO:0044454;nuclear chromosome part;0.00709774111471795!GO:0000725;recombinational repair;0.00709774111471795!GO:0000724;double-strand break repair via homologous recombination;0.00709774111471795!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00712440325039419!GO:0030127;COPII vesicle coat;0.00756319111275546!GO:0012507;ER to Golgi transport vesicle membrane;0.00756319111275546!GO:0016049;cell growth;0.00757353164157424!GO:0006595;polyamine metabolic process;0.00758912513202235!GO:0006916;anti-apoptosis;0.00765444275451231!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.00767761346882495!GO:0000178;exosome (RNase complex);0.00771743167676126!GO:0004003;ATP-dependent DNA helicase activity;0.00774384639171893!GO:0030137;COPI-coated vesicle;0.00788365304945967!GO:0005832;chaperonin-containing T-complex;0.0078911015638133!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0078911015638133!GO:0043130;ubiquitin binding;0.0078911015638133!GO:0032182;small conjugating protein binding;0.0078911015638133!GO:0008139;nuclear localization sequence binding;0.00794280680597404!GO:0000152;nuclear ubiquitin ligase complex;0.00803707354979682!GO:0006497;protein amino acid lipidation;0.00838017405160375!GO:0051098;regulation of binding;0.00838017405160375!GO:0003923;GPI-anchor transamidase activity;0.00838017405160375!GO:0016255;attachment of GPI anchor to protein;0.00838017405160375!GO:0042765;GPI-anchor transamidase complex;0.00838017405160375!GO:0008610;lipid biosynthetic process;0.00851700531439602!GO:0051540;metal cluster binding;0.00900890405776182!GO:0051536;iron-sulfur cluster binding;0.00900890405776182!GO:0006289;nucleotide-excision repair;0.00906378029263971!GO:0016491;oxidoreductase activity;0.00928179113667157!GO:0009303;rRNA transcription;0.00959166186602616!GO:0051920;peroxiredoxin activity;0.00959889947219485!GO:0008276;protein methyltransferase activity;0.00966483194314926!GO:0045045;secretory pathway;0.00995051718973682!GO:0045892;negative regulation of transcription, DNA-dependent;0.0101776783570934!GO:0000339;RNA cap binding;0.0102155959780997!GO:0007346;regulation of progression through mitotic cell cycle;0.0102900136659205!GO:0005669;transcription factor TFIID complex;0.0106415878003589!GO:0001558;regulation of cell growth;0.0109239194823291!GO:0051053;negative regulation of DNA metabolic process;0.0115690958215484!GO:0045936;negative regulation of phosphate metabolic process;0.0116020949784977!GO:0016584;nucleosome positioning;0.011604701217009!GO:0005853;eukaryotic translation elongation factor 1 complex;0.0117393779243299!GO:0016272;prefoldin complex;0.0117675050816569!GO:0030125;clathrin vesicle coat;0.0120372225962601!GO:0030665;clathrin coated vesicle membrane;0.0120372225962601!GO:0031577;spindle checkpoint;0.0120708832803949!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;0.0120816531534758!GO:0008180;signalosome;0.0123048058533456!GO:0031570;DNA integrity checkpoint;0.0124651026421847!GO:0005862;muscle thin filament tropomyosin;0.0125730115067456!GO:0007021;tubulin folding;0.0125799215600465!GO:0000086;G2/M transition of mitotic cell cycle;0.01270283330385!GO:0007264;small GTPase mediated signal transduction;0.012726701648184!GO:0008408;3'-5' exonuclease activity;0.0129633092857367!GO:0019843;rRNA binding;0.0131806340768611!GO:0042770;DNA damage response, signal transduction;0.0137310459179211!GO:0006091;generation of precursor metabolites and energy;0.0138897585106326!GO:0043022;ribosome binding;0.0139325774138305!GO:0043189;H4/H2A histone acetyltransferase complex;0.0143826285270842!GO:0035267;NuA4 histone acetyltransferase complex;0.0145283834750308!GO:0000323;lytic vacuole;0.0145793461925348!GO:0005764;lysosome;0.0145793461925348!GO:0008287;protein serine/threonine phosphatase complex;0.0147597667927266!GO:0030029;actin filament-based process;0.0149605385896992!GO:0030496;midbody;0.0149605385896992!GO:0016197;endosome transport;0.0157869024736276!GO:0016301;kinase activity;0.0159141507280058!GO:0046822;regulation of nucleocytoplasmic transport;0.0159914508790395!GO:0000726;non-recombinational repair;0.0161294211273577!GO:0044262;cellular carbohydrate metabolic process;0.0161887774222755!GO:0000793;condensed chromosome;0.016510840510843!GO:0030140;trans-Golgi network transport vesicle;0.0173325922208724!GO:0004532;exoribonuclease activity;0.0175332963222279!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0175332963222279!GO:0046128;purine ribonucleoside metabolic process;0.0176750190719976!GO:0042278;purine nucleoside metabolic process;0.0176750190719976!GO:0008536;Ran GTPase binding;0.0180131531206741!GO:0016585;chromatin remodeling complex;0.0181495778105617!GO:0030027;lamellipodium;0.019462846677428!GO:0045893;positive regulation of transcription, DNA-dependent;0.019496663567163!GO:0043492;ATPase activity, coupled to movement of substances;0.0195461168262806!GO:0005663;DNA replication factor C complex;0.0198543264124887!GO:0008286;insulin receptor signaling pathway;0.0198543264124887!GO:0065009;regulation of a molecular function;0.0208869062895663!GO:0005869;dynactin complex;0.0209225301110929!GO:0040029;regulation of gene expression, epigenetic;0.0210617172121006!GO:0006376;mRNA splice site selection;0.0218115996922221!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0218115996922221!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.0222705746287325!GO:0000123;histone acetyltransferase complex;0.0226267274115375!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0226339699821116!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.0228793193579734!GO:0016579;protein deubiquitination;0.0229623448128606!GO:0042158;lipoprotein biosynthetic process;0.0229861595110466!GO:0022890;inorganic cation transmembrane transporter activity;0.0235101671602419!GO:0005875;microtubule associated complex;0.0237417703700184!GO:0043631;RNA polyadenylation;0.0237620126094584!GO:0008538;proteasome activator activity;0.0240389053759067!GO:0050681;androgen receptor binding;0.0241639163585213!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.0242061087210134!GO:0003887;DNA-directed DNA polymerase activity;0.0242061087210134!GO:0008234;cysteine-type peptidase activity;0.0244834542276073!GO:0016408;C-acyltransferase activity;0.0246363753575541!GO:0000209;protein polyubiquitination;0.025009520549222!GO:0008270;zinc ion binding;0.0250383043213224!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0250762378680643!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0254488597062213!GO:0015002;heme-copper terminal oxidase activity;0.0254488597062213!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0254488597062213!GO:0004129;cytochrome-c oxidase activity;0.0254488597062213!GO:0032984;macromolecular complex disassembly;0.0254573989454829!GO:0005658;alpha DNA polymerase:primase complex;0.0254613436269578!GO:0003857;3-hydroxyacyl-CoA dehydrogenase activity;0.0255672579903447!GO:0047485;protein N-terminus binding;0.026410941207202!GO:0003756;protein disulfide isomerase activity;0.0264546694837239!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0264546694837239!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.0269451326090835!GO:0019752;carboxylic acid metabolic process;0.0270293999626891!GO:0005652;nuclear lamina;0.0270293999626891!GO:0042326;negative regulation of phosphorylation;0.0272409439231455!GO:0043624;cellular protein complex disassembly;0.027407193287377!GO:0050662;coenzyme binding;0.0289843718468992!GO:0009113;purine base biosynthetic process;0.0301157260063548!GO:0006672;ceramide metabolic process;0.0301455373910195!GO:0009304;tRNA transcription;0.0310436049383341!GO:0000096;sulfur amino acid metabolic process;0.0313355289325545!GO:0009451;RNA modification;0.0320274467365878!GO:0006082;organic acid metabolic process;0.0321398589212214!GO:0008156;negative regulation of DNA replication;0.0321398589212214!GO:0005680;anaphase-promoting complex;0.0321398589212214!GO:0000084;S phase of mitotic cell cycle;0.0323662151639298!GO:0005784;translocon complex;0.0327578901809503!GO:0030145;manganese ion binding;0.03320271156514!GO:0044438;microbody part;0.03320271156514!GO:0044439;peroxisomal part;0.03320271156514!GO:0051320;S phase;0.033206854093213!GO:0042791;5S class rRNA transcription;0.033456262868589!GO:0000127;transcription factor TFIIIC complex;0.033456262868589!GO:0042797;tRNA transcription from RNA polymerase III promoter;0.033456262868589!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0339858656424546!GO:0046426;negative regulation of JAK-STAT cascade;0.0348383186997478!GO:0043241;protein complex disassembly;0.0354940854976601!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0355439290378192!GO:0032507;maintenance of cellular protein localization;0.0357849227125013!GO:0031625;ubiquitin protein ligase binding;0.0357998148103746!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0358183503639436!GO:0006220;pyrimidine nucleotide metabolic process;0.0359102649543943!GO:0005856;cytoskeleton;0.0364128530262386!GO:0042026;protein refolding;0.0364138568516985!GO:0005758;mitochondrial intermembrane space;0.0367938968588355!GO:0022411;cellular component disassembly;0.036803914242627!GO:0000118;histone deacetylase complex;0.0371321580311313!GO:0004347;glucose-6-phosphate isomerase activity;0.037179739402836!GO:0005521;lamin binding;0.0376751635893027!GO:0005938;cell cortex;0.03836347830217!GO:0045792;negative regulation of cell size;0.0386410796417294!GO:0001832;blastocyst growth;0.0387071421885501!GO:0007094;mitotic cell cycle spindle assembly checkpoint;0.039061537444788!GO:0008475;procollagen-lysine 5-dioxygenase activity;0.0394088973311662!GO:0004185;serine carboxypeptidase activity;0.0397154549368974!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0400884211738239!GO:0010257;NADH dehydrogenase complex assembly;0.0400884211738239!GO:0033108;mitochondrial respiratory chain complex assembly;0.0400884211738239!GO:0030522;intracellular receptor-mediated signaling pathway;0.0402084459760325!GO:0000077;DNA damage checkpoint;0.0408405239093511!GO:0001711;endodermal cell fate commitment;0.0411573686042464!GO:0030858;positive regulation of epithelial cell differentiation;0.0411573686042464!GO:0031528;microvillus membrane;0.0411573686042464!GO:0001706;endoderm formation;0.0411573686042464!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0426157245433401!GO:0009124;nucleoside monophosphate biosynthetic process;0.0426157245433401!GO:0009123;nucleoside monophosphate metabolic process;0.0426157245433401!GO:0004722;protein serine/threonine phosphatase activity;0.0428617288810399!GO:0044450;microtubule organizing center part;0.0430293404470254!GO:0006541;glutamine metabolic process;0.0433588962832691!GO:0006360;transcription from RNA polymerase I promoter;0.0433904430830431!GO:0043550;regulation of lipid kinase activity;0.0436079382317966!GO:0031903;microbody membrane;0.0446494233149579!GO:0005778;peroxisomal membrane;0.0446494233149579!GO:0003725;double-stranded RNA binding;0.0450751148485291!GO:0017134;fibroblast growth factor binding;0.0450919313926971!GO:0007265;Ras protein signal transduction;0.0457624636713102!GO:0006520;amino acid metabolic process;0.0461573823136462!GO:0043488;regulation of mRNA stability;0.0463196813585715!GO:0043487;regulation of RNA stability;0.0463196813585715!GO:0019902;phosphatase binding;0.0463705779187289!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0463705779187289!GO:0043433;negative regulation of transcription factor activity;0.0463784158881885!GO:0042769;DNA damage response, detection of DNA damage;0.046548008428332!GO:0032200;telomere organization and biogenesis;0.0469198915774932!GO:0000723;telomere maintenance;0.0469198915774932!GO:0016884;carbon-nitrogen ligase activity, with glutamine as amido-N-donor;0.0473573695119823!GO:0006301;postreplication repair;0.0476139831829374!GO:0030433;ER-associated protein catabolic process;0.0483200452357489!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0483200452357489!GO:0001725;stress fiber;0.0483393126545353!GO:0032432;actin filament bundle;0.0483393126545353!GO:0003985;acetyl-CoA C-acetyltransferase activity;0.0488034899731487!GO:0051059;NF-kappaB binding;0.0488334036048716!GO:0031227;intrinsic to endoplasmic reticulum membrane;0.0489347021044574!GO:0046519;sphingoid metabolic process;0.0495223170841041!GO:0030308;negative regulation of cell growth;0.0495674562081338!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0495674562081338!GO:0008143;poly(A) binding;0.0498762433058483 | |||
|sample_id=12858 | |sample_id=12858 | ||
|sample_note= | |sample_note= | ||
| Line 75: | Line 104: | ||
|sample_strain= | |sample_strain= | ||
|sample_tissue= | |sample_tissue= | ||
|time= 00hr00min | |||
|timecourse=Saos_calcification | |||
|top_motifs=PDX1:3.34856306467;TFDP1:2.00479404236;PITX1..3:1.824789371;VSX1,2:1.82285913951;E2F1..5:1.72389785631;HOX{A4,D4}:1.716375558;NFY{A,B,C}:1.67571996921;PRRX1,2:1.62248633576;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.58047538917;NRF1:1.56915253589;POU1F1:1.50436344848;NKX2-3_NKX2-5:1.49272384955;ZNF143:1.25700381361;FOXA2:1.16285553122;NKX3-1:1.14511895242;GFI1:1.12885732654;YY1:1.09517099654;EN1,2:1.07061535412;FOXP1:1.0156728378;CUX2:0.948017872695;TOPORS:0.938449582549;MEF2{A,B,C,D}:0.923044675382;SOX17:0.906532900886;HIC1:0.893481246557;BREu{core}:0.855944916673;NANOG:0.850730077912;EVI1:0.778542666747;NFIX:0.745257423361;CDC5L:0.734446447709;TGIF1:0.703217365233;HIF1A:0.685538593457;NKX6-1,2:0.678865522454;STAT5{A,B}:0.674982335554;FOXQ1:0.670332603821;NKX2-1,4:0.669600406314;PBX1:0.661003773974;FOX{F1,F2,J1}:0.660523250562;LEF1_TCF7_TCF7L1,2:0.586047309503;MYB:0.571412454823;ELK1,4_GABP{A,B1}:0.534980099618;AHR_ARNT_ARNT2:0.532550309193;PAX2:0.485851803527;HES1:0.480225866788;PAX8:0.479328191766;T:0.465366494983;MZF1:0.450910874129;SOX{8,9,10}:0.437796282483;POU3F1..4:0.43420464522;SREBF1,2:0.429828820965;NFE2L2:0.427215900089;PAX4:0.420114355837;LHX3,4:0.416891272161;ATF4:0.403428585431;SP1:0.403052217796;PAX1,9:0.392490883767;PAX6:0.391211082541;ZNF384:0.372429610305;ZFP161:0.361242305883;ONECUT1,2:0.350796897378;TEAD1:0.285986353564;ATF6:0.28140347985;PAX3,7:0.262952781293;RUNX1..3:0.257816152633;FOX{I1,J2}:0.253274484518;RBPJ:0.234289813922;ZNF423:0.227612989714;FOXD3:0.225584278883;JUN:0.217894192633;MYBL2:0.216530159613;RORA:0.212874688947;DBP:0.202811649965;STAT1,3:0.199142069362;CDX1,2,4:0.19203615022;ZBTB16:0.185904049265;IKZF2:0.149509749605;RREB1:0.141869484314;TFAP2B:0.140333037193;GTF2I:0.140310622128;ATF5_CREB3:0.130102283415;OCT4_SOX2{dimer}:0.125901555075;FOXM1:0.118738886951;NR3C1:0.111556556927;NR1H4:0.0928335710051;HOX{A5,B5}:0.0783543677506;XCPE1{core}:0.0738398069923;POU6F1:0.0462695035528;IKZF1:0.0417631018968;ADNP_IRX_SIX_ZHX:0.0414091331149;TEF:0.0387390161162;EGR1..3:0.032068342969;HOXA9_MEIS1:0.0238284633509;RFX1:0.00943879657165;TBX4,5:-0.000137778184734;CREB1:-0.000451496978721;XBP1:-0.00134397830103;bHLH_family:-0.0139489673546;AIRE:-0.0224114650458;FOXN1:-0.0287028652026;AR:-0.043790796759;HNF1A:-0.0465188614363;RXR{A,B,G}:-0.0611319043853;PATZ1:-0.0720533671655;NFE2:-0.0733327636794;SOX2:-0.0758739656992;NR6A1:-0.0962340579678;ARID5B:-0.110301356634;MYFfamily:-0.116310123681;ESR1:-0.125727331342;ZBTB6:-0.127697781047;NR5A1,2:-0.130756664964;POU5F1:-0.142366460344;MED-1{core}:-0.159446573664;FOSL2:-0.171297911915;MAZ:-0.183419516947;ESRRA:-0.189382400097;ELF1,2,4:-0.190117088793;NHLH1,2:-0.195460615543;ZIC1..3:-0.195906006843;BACH2:-0.209323939154;IRF7:-0.211160920955;PAX5:-0.213658754462;GZF1:-0.216903708285;MTE{core}:-0.217533901855;GATA6:-0.221592995602;CRX:-0.242117461352;PRDM1:-0.247918160764;FOS_FOS{B,L1}_JUN{B,D}:-0.257539168813;RFX2..5_RFXANK_RFXAP:-0.283624140397;FOXP3:-0.284886985002;FOXL1:-0.297984460668;TFAP4:-0.299895327421;GCM1,2:-0.300716633111;DMAP1_NCOR{1,2}_SMARC:-0.304620783907;HLF:-0.308421155361;ZNF238:-0.308811759511;GTF2A1,2:-0.315443915464;EBF1:-0.330110419471;HNF4A_NR2F1,2:-0.330398195349;NKX2-2,8:-0.340440423202;GFI1B:-0.346787471318;REST:-0.36313308099;SOX5:-0.371877598641;NFE2L1:-0.382116561605;SMAD1..7,9:-0.382601114897;TP53:-0.387131061981;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.388307807188;TLX1..3_NFIC{dimer}:-0.391071528956;ALX4:-0.422732335365;GLI1..3:-0.443035429652;BPTF:-0.454996283265;ZNF148:-0.465552456924;IRF1,2:-0.467708124161;KLF4:-0.47590656397;UFEwm:-0.484715345029;FOX{D1,D2}:-0.522356956836;SPIB:-0.529030118118;NFIL3:-0.529878177035;PPARG:-0.531014924529;MAFB:-0.535299458695;NFKB1_REL_RELA:-0.538148270524;NKX3-2:-0.538761711655;TFCP2:-0.542211894152;SRF:-0.579209151632;SNAI1..3:-0.579754618306;SPI1:-0.622813114415;ATF2:-0.637379662022;ZEB1:-0.673682489895;HAND1,2:-0.675086503799;LMO2:-0.676319754395;SPZ1:-0.680037809295;POU2F1..3:-0.689253809596;HBP1_HMGB_SSRP1_UBTF:-0.706801088756;TAL1_TCF{3,4,12}:-0.71749602553;ETS1,2:-0.720976567806;MYOD1:-0.750290398678;CEBPA,B_DDIT3:-0.758654223828;HOX{A6,A7,B6,B7}:-0.760129837711;MTF1:-0.765491223085;GATA4:-0.768748416423;TFAP2{A,C}:-0.770339822235;ALX1:-0.797282047652;HMX1:-0.812575201483;NANOG{mouse}:-0.863728046227;NFATC1..3:-0.96393133644;STAT2,4,6:-0.969590526198;RXRA_VDR{dimer}:-1.08301928377;TLX2:-1.10367273623;HMGA1,2:-1.11380430917;HSF1,2:-1.15222904573;EP300:-1.19893519348;TBP:-1.27245278536;FOXO1,3,4:-1.37577963964 | |top_motifs=PDX1:3.34856306467;TFDP1:2.00479404236;PITX1..3:1.824789371;VSX1,2:1.82285913951;E2F1..5:1.72389785631;HOX{A4,D4}:1.716375558;NFY{A,B,C}:1.67571996921;PRRX1,2:1.62248633576;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.58047538917;NRF1:1.56915253589;POU1F1:1.50436344848;NKX2-3_NKX2-5:1.49272384955;ZNF143:1.25700381361;FOXA2:1.16285553122;NKX3-1:1.14511895242;GFI1:1.12885732654;YY1:1.09517099654;EN1,2:1.07061535412;FOXP1:1.0156728378;CUX2:0.948017872695;TOPORS:0.938449582549;MEF2{A,B,C,D}:0.923044675382;SOX17:0.906532900886;HIC1:0.893481246557;BREu{core}:0.855944916673;NANOG:0.850730077912;EVI1:0.778542666747;NFIX:0.745257423361;CDC5L:0.734446447709;TGIF1:0.703217365233;HIF1A:0.685538593457;NKX6-1,2:0.678865522454;STAT5{A,B}:0.674982335554;FOXQ1:0.670332603821;NKX2-1,4:0.669600406314;PBX1:0.661003773974;FOX{F1,F2,J1}:0.660523250562;LEF1_TCF7_TCF7L1,2:0.586047309503;MYB:0.571412454823;ELK1,4_GABP{A,B1}:0.534980099618;AHR_ARNT_ARNT2:0.532550309193;PAX2:0.485851803527;HES1:0.480225866788;PAX8:0.479328191766;T:0.465366494983;MZF1:0.450910874129;SOX{8,9,10}:0.437796282483;POU3F1..4:0.43420464522;SREBF1,2:0.429828820965;NFE2L2:0.427215900089;PAX4:0.420114355837;LHX3,4:0.416891272161;ATF4:0.403428585431;SP1:0.403052217796;PAX1,9:0.392490883767;PAX6:0.391211082541;ZNF384:0.372429610305;ZFP161:0.361242305883;ONECUT1,2:0.350796897378;TEAD1:0.285986353564;ATF6:0.28140347985;PAX3,7:0.262952781293;RUNX1..3:0.257816152633;FOX{I1,J2}:0.253274484518;RBPJ:0.234289813922;ZNF423:0.227612989714;FOXD3:0.225584278883;JUN:0.217894192633;MYBL2:0.216530159613;RORA:0.212874688947;DBP:0.202811649965;STAT1,3:0.199142069362;CDX1,2,4:0.19203615022;ZBTB16:0.185904049265;IKZF2:0.149509749605;RREB1:0.141869484314;TFAP2B:0.140333037193;GTF2I:0.140310622128;ATF5_CREB3:0.130102283415;OCT4_SOX2{dimer}:0.125901555075;FOXM1:0.118738886951;NR3C1:0.111556556927;NR1H4:0.0928335710051;HOX{A5,B5}:0.0783543677506;XCPE1{core}:0.0738398069923;POU6F1:0.0462695035528;IKZF1:0.0417631018968;ADNP_IRX_SIX_ZHX:0.0414091331149;TEF:0.0387390161162;EGR1..3:0.032068342969;HOXA9_MEIS1:0.0238284633509;RFX1:0.00943879657165;TBX4,5:-0.000137778184734;CREB1:-0.000451496978721;XBP1:-0.00134397830103;bHLH_family:-0.0139489673546;AIRE:-0.0224114650458;FOXN1:-0.0287028652026;AR:-0.043790796759;HNF1A:-0.0465188614363;RXR{A,B,G}:-0.0611319043853;PATZ1:-0.0720533671655;NFE2:-0.0733327636794;SOX2:-0.0758739656992;NR6A1:-0.0962340579678;ARID5B:-0.110301356634;MYFfamily:-0.116310123681;ESR1:-0.125727331342;ZBTB6:-0.127697781047;NR5A1,2:-0.130756664964;POU5F1:-0.142366460344;MED-1{core}:-0.159446573664;FOSL2:-0.171297911915;MAZ:-0.183419516947;ESRRA:-0.189382400097;ELF1,2,4:-0.190117088793;NHLH1,2:-0.195460615543;ZIC1..3:-0.195906006843;BACH2:-0.209323939154;IRF7:-0.211160920955;PAX5:-0.213658754462;GZF1:-0.216903708285;MTE{core}:-0.217533901855;GATA6:-0.221592995602;CRX:-0.242117461352;PRDM1:-0.247918160764;FOS_FOS{B,L1}_JUN{B,D}:-0.257539168813;RFX2..5_RFXANK_RFXAP:-0.283624140397;FOXP3:-0.284886985002;FOXL1:-0.297984460668;TFAP4:-0.299895327421;GCM1,2:-0.300716633111;DMAP1_NCOR{1,2}_SMARC:-0.304620783907;HLF:-0.308421155361;ZNF238:-0.308811759511;GTF2A1,2:-0.315443915464;EBF1:-0.330110419471;HNF4A_NR2F1,2:-0.330398195349;NKX2-2,8:-0.340440423202;GFI1B:-0.346787471318;REST:-0.36313308099;SOX5:-0.371877598641;NFE2L1:-0.382116561605;SMAD1..7,9:-0.382601114897;TP53:-0.387131061981;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.388307807188;TLX1..3_NFIC{dimer}:-0.391071528956;ALX4:-0.422732335365;GLI1..3:-0.443035429652;BPTF:-0.454996283265;ZNF148:-0.465552456924;IRF1,2:-0.467708124161;KLF4:-0.47590656397;UFEwm:-0.484715345029;FOX{D1,D2}:-0.522356956836;SPIB:-0.529030118118;NFIL3:-0.529878177035;PPARG:-0.531014924529;MAFB:-0.535299458695;NFKB1_REL_RELA:-0.538148270524;NKX3-2:-0.538761711655;TFCP2:-0.542211894152;SRF:-0.579209151632;SNAI1..3:-0.579754618306;SPI1:-0.622813114415;ATF2:-0.637379662022;ZEB1:-0.673682489895;HAND1,2:-0.675086503799;LMO2:-0.676319754395;SPZ1:-0.680037809295;POU2F1..3:-0.689253809596;HBP1_HMGB_SSRP1_UBTF:-0.706801088756;TAL1_TCF{3,4,12}:-0.71749602553;ETS1,2:-0.720976567806;MYOD1:-0.750290398678;CEBPA,B_DDIT3:-0.758654223828;HOX{A6,A7,B6,B7}:-0.760129837711;MTF1:-0.765491223085;GATA4:-0.768748416423;TFAP2{A,C}:-0.770339822235;ALX1:-0.797282047652;HMX1:-0.812575201483;NANOG{mouse}:-0.863728046227;NFATC1..3:-0.96393133644;STAT2,4,6:-0.969590526198;RXRA_VDR{dimer}:-1.08301928377;TLX2:-1.10367273623;HMGA1,2:-1.11380430917;HSF1,2:-1.15222904573;EP300:-1.19893519348;TBP:-1.27245278536;FOXO1,3,4:-1.37577963964 | ||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:12858-137D5;search_select_hide=table117:FF:12858-137D5 | |||
}} | }} | ||
Latest revision as of 18:46, 4 June 2020
| Name: | Saos-2 osteosarcoma treated with ascorbic acid and BGP to induce calcification |
|---|---|
| Species: | Human (Homo sapiens) |
| Library ID: | CNhs12952 |
| Sample type: | time courses |
| Genomic View: | UCSC |
| RefEX: | Specific genes |
| CAGEd-oPOSSUM: | link |
| ZENBU report : | link |
| Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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| Download raw sequence, BAM & CTSS | ||||||||||||||
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| RNA-Seq Accession numbers | ||||||||||||||||||||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12952
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12952
| Novel motif | Logo | P-value |
|---|---|---|
| 1 | 1 | 0.398 |
| 10 | 10 | 0.888 |
| 100 | 100 | 0.403 |
| 101 | 101 | 0.858 |
| 102 | 102 | 0.539 |
| 103 | 103 | 0.0209 |
| 104 | 104 | 0.699 |
| 105 | 105 | 0.666 |
| 106 | 106 | 1.99431e-4 |
| 107 | 107 | 0.0311 |
| 108 | 108 | 0.607 |
| 109 | 109 | 0.171 |
| 11 | 11 | 0.112 |
| 110 | 110 | 0.407 |
| 111 | 111 | 0.353 |
| 112 | 112 | 0.023 |
| 113 | 113 | 0.462 |
| 114 | 114 | 0.027 |
| 115 | 115 | 0.135 |
| 116 | 116 | 0.814 |
| 117 | 117 | 0.674 |
| 118 | 118 | 0.427 |
| 119 | 119 | 0.0757 |
| 12 | 12 | 0.728 |
| 120 | 120 | 0.21 |
| 121 | 121 | 0.388 |
| 122 | 122 | 0.621 |
| 123 | 123 | 0.975 |
| 124 | 124 | 0.413 |
| 125 | 125 | 0.117 |
| 126 | 126 | 0.254 |
| 127 | 127 | 0.644 |
| 128 | 128 | 0.00678 |
| 129 | 129 | 0.198 |
| 13 | 13 | 0.607 |
| 130 | 130 | 0.0516 |
| 131 | 131 | 0.268 |
| 132 | 132 | 0.311 |
| 133 | 133 | 0.692 |
| 134 | 134 | 0.922 |
| 135 | 135 | 0.108 |
| 136 | 136 | 0.556 |
| 137 | 137 | 0.23 |
| 138 | 138 | 0.663 |
| 139 | 139 | 0.00354 |
| 14 | 14 | 0.463 |
| 140 | 140 | 0.235 |
| 141 | 141 | 0.452 |
| 142 | 142 | 0.871 |
| 143 | 143 | 0.0189 |
| 144 | 144 | 0.514 |
| 145 | 145 | 0.128 |
| 146 | 146 | 0.754 |
| 147 | 147 | 0.838 |
| 148 | 148 | 0.0655 |
| 149 | 149 | 0.0935 |
| 15 | 15 | 0.519 |
| 150 | 150 | 0.545 |
| 151 | 151 | 0.207 |
| 152 | 152 | 0.0203 |
| 153 | 153 | 0.181 |
| 154 | 154 | 0.614 |
| 155 | 155 | 0.601 |
| 156 | 156 | 0.518 |
| 157 | 157 | 0.463 |
| 158 | 158 | 0.759 |
| 159 | 159 | 0.572 |
| 16 | 16 | 0.195 |
| 160 | 160 | 0.339 |
| 161 | 161 | 0.941 |
| 162 | 162 | 0.835 |
| 163 | 163 | 0.865 |
| 164 | 164 | 0.664 |
| 165 | 165 | 0.683 |
| 166 | 166 | 0.696 |
| 167 | 167 | 0.0908 |
| 168 | 168 | 0.151 |
| 169 | 169 | 0.0335 |
| 17 | 17 | 0.12 |
| 18 | 18 | 0.0704 |
| 19 | 19 | 0.141 |
| 2 | 2 | 0.232 |
| 20 | 20 | 0.287 |
| 21 | 21 | 0.793 |
| 22 | 22 | 0.189 |
| 23 | 23 | 0.0131 |
| 24 | 24 | 0.77 |
| 25 | 25 | 0.935 |
| 26 | 26 | 0.527 |
| 27 | 27 | 0.0227 |
| 28 | 28 | 0.903 |
| 29 | 29 | 0.547 |
| 3 | 3 | 0.104 |
| 30 | 30 | 0.426 |
| 31 | 31 | 0.491 |
| 32 | 32 | 0.0689 |
| 33 | 33 | 0.627 |
| 34 | 34 | 0.334 |
| 35 | 35 | 0.238 |
| 36 | 36 | 0.689 |
| 37 | 37 | 0.136 |
| 38 | 38 | 0.32 |
| 39 | 39 | 0.105 |
| 4 | 4 | 0.432 |
| 40 | 40 | 0.489 |
| 41 | 41 | 0.144 |
| 42 | 42 | 0.326 |
| 43 | 43 | 0.158 |
| 44 | 44 | 0.0168 |
| 45 | 45 | 0.13 |
| 46 | 46 | 0.137 |
| 47 | 47 | 0.355 |
| 48 | 48 | 0.527 |
| 49 | 49 | 0.253 |
| 5 | 5 | 0.388 |
| 50 | 50 | 0.411 |
| 51 | 51 | 0.517 |
| 52 | 52 | 0.148 |
| 53 | 53 | 0.843 |
| 54 | 54 | 0.301 |
| 55 | 55 | 0.078 |
| 56 | 56 | 0.456 |
| 57 | 57 | 0.839 |
| 58 | 58 | 0.185 |
| 59 | 59 | 0.0785 |
| 6 | 6 | 0.492 |
| 60 | 60 | 0.0322 |
| 61 | 61 | 0.987 |
| 62 | 62 | 0.0876 |
| 63 | 63 | 0.161 |
| 64 | 64 | 0.495 |
| 65 | 65 | 0.0233 |
| 66 | 66 | 0.145 |
| 67 | 67 | 0.653 |
| 68 | 68 | 0.602 |
| 69 | 69 | 0.686 |
| 7 | 7 | 0.774 |
| 70 | 70 | 0.00708 |
| 71 | 71 | 0.29 |
| 72 | 72 | 0.0684 |
| 73 | 73 | 0.0511 |
| 74 | 74 | 0.299 |
| 75 | 75 | 0.544 |
| 76 | 76 | 0.698 |
| 77 | 77 | 0.107 |
| 78 | 78 | 0.666 |
| 79 | 79 | 0.00291 |
| 8 | 8 | 0.311 |
| 80 | 80 | 0.197 |
| 81 | 81 | 0.431 |
| 82 | 82 | 0.0257 |
| 83 | 83 | 0.775 |
| 84 | 84 | 0.842 |
| 85 | 85 | 0.00148 |
| 86 | 86 | 0.364 |
| 87 | 87 | 0.699 |
| 88 | 88 | 0.376 |
| 89 | 89 | 0.00809 |
| 9 | 9 | 0.174 |
| 90 | 90 | 0.363 |
| 91 | 91 | 0.402 |
| 92 | 92 | 0.127 |
| 93 | 93 | 0.828 |
| 94 | 94 | 0.0333 |
| 95 | 95 | 0.343 |
| 96 | 96 | 0.414 |
| 97 | 97 | 0.973 |
| 98 | 98 | 0.237 |
| 99 | 99 | 0.524 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs12952
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000593 human Saos2 osteosarcoma cell line 0min after induction of calcification with ascorbate and BPG sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000055 (non-terminally differentiated cell)
0000003 (native cell)
0000548 (animal cell)
0002320 (connective tissue cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
0000062 (osteoblast)
UBERON: Anatomy
0000468 (multi-cellular organism)
0001474 (bone element)
0002384 (connective tissue)
0000479 (tissue)
0000062 (organ)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0004765 (skeletal element)
0002204 (musculoskeletal system)
0001434 (skeletal system)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0000350 (experimentally modified sample)
0000344 (0 minute sample)
0000332 (calcification induced with ascorbate and BPG sample)
0100971 (SAOS-2 cell sample)
0100385 (bone cancer cell line sample)
0100407 (osteosarcoma cell line sample)
0000593 (human Saos2 osteosarcoma cell line 0min after induction of calcification with ascorbate and BPG sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)
CL:0000335 (mesenchyme condensation cell)
