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{{Coexpression_clusters
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|full_id=C1408_Iris_Ciliary_Lens_Retinal_Astrocyte_Smooth_testicular
|id=C1408
|ontology_enrichment_celltype=CL:0000064!1.57e-08!3;CL:0005012!1.57e-08!3;CL:0000067!1.57e-08!3;CL:0002304!1.57e-08!3;CL:0002586!4.32e-08!3;CL:0000147!1.74e-07!14;CL:0000708!3.30e-07!3
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0007625!1.53e-21!11;UBERON:0000970!4.52e-15!20;UBERON:0000020!4.71e-15!23;UBERON:0001032!2.82e-14!24;UBERON:0004456!2.82e-14!24;UBERON:0002104!3.37e-14!21;UBERON:0000019!1.99e-13!19;UBERON:0000047!1.99e-13!19;UBERON:0004088!1.99e-13!19;UBERON:0003072!1.99e-13!19;UBERON:0003071!1.99e-13!19;UBERON:0004128!1.99e-13!19;UBERON:0001456!7.05e-12!21;UBERON:0000488!7.62e-11!4;UBERON:0005085!2.10e-09!29;UBERON:0001778!1.57e-08!3;UBERON:0001775!1.57e-08!3;UBERON:0001781!4.32e-08!3;UBERON:0001782!4.32e-08!3;UBERON:0005424!4.32e-08!3;UBERON:0001801!4.53e-08!14;UBERON:0000063!8.16e-08!97;UBERON:0000966!1.42e-07!5;UBERON:0005388!1.42e-07!5;UBERON:0001802!1.42e-07!5;UBERON:0001444!1.74e-07!48;UBERON:0002200!2.11e-07!11;UBERON:0006876!2.11e-07!11;UBERON:0003210!3.30e-07!3;UBERON:0002203!3.72e-07!6;UBERON:0001768!3.72e-07!6
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}}

Latest revision as of 11:44, 17 September 2013


Full id: C1408_Iris_Ciliary_Lens_Retinal_Astrocyte_Smooth_testicular



Phase1 CAGE Peaks

Hg19::chr15:71583868..71583874,-p@chr15:71583868..71583874
-
Hg19::chr2:35680607..35680613,-p@chr2:35680607..35680613
-
Hg19::chr5:78112479..78112482,+p@chr5:78112479..78112482
+
Hg19::chr7:131803806..131803815,+p@chr7:131803806..131803815
+
Hg19::chr8:53853672..53853682,-p1@BC033145
Hg19::chr8:53853688..53853698,-p3@BC033145


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
pigment epithelium of eye9.88e-12711
atypical epithelium2.29e-884
anterior segment of eyeball1.72e-7614
camera-type eye8.04e-7020
simple eye8.04e-7020
immature eye8.04e-7020
ocular region8.04e-7020
eyeball of camera-type eye8.04e-7020
optic cup8.04e-7020
optic vesicle8.04e-7020
eye primordium8.04e-7020
ciliary epithelium1.54e-663
ciliary body1.54e-663
eye1.66e-6621
visual system1.66e-6621
face1.72e-6322
vasculature of eye3.54e-596
uvea3.54e-596
vasculature of head3.54e-596
sense organ3.25e-5824
sensory system3.25e-5824
entire sense organ system3.25e-5824
cuboidal epithelium1.19e-494
transparent eye structure1.19e-494
simple cuboidal epithelium1.19e-494
cranial placode1.19e-494
lens of camera-type eye1.19e-494
epithelium of lens1.19e-494
lens placode1.19e-494
lens vesicle1.19e-494
ectodermal placode4.24e-4531
vasculature of organ1.37e-3211
subdivision of head1.50e-2849
external ectoderm2.80e-258
head5.60e-2556
iris epithelium1.07e-231
iris1.07e-231
anterior region of body1.48e-2262
craniocervical region1.48e-2262
pre-chordal neural plate1.48e-2261
neural plate7.98e-1782
presumptive neural plate7.98e-1782
neurectoderm4.81e-1686
organ segment3.17e-1498
ecto-epithelium2.90e-13104
uterine epithelium3.62e-122
cervix epithelium3.62e-122
structure with developmental contribution from neural crest2.01e-10132
pigmented layer of retina1.21e-083
presumptive retinal pigmented epithelium1.21e-083
primordium1.29e-08160
ectoderm-derived structure6.76e-08171
ectoderm6.76e-08171
presumptive ectoderm6.76e-08171
organ part6.82e-08218
layer of retina8.61e-074


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.321379
MA0004.10.558729
MA0006.10.391183
MA0007.10.539222
MA0009.11.03681
MA0014.10.108006
MA0017.10.432438
MA0019.10.7124
MA0024.10.929647
MA0025.11.17262
MA0027.12.65688
MA0028.10.408079
MA0029.10.949428
MA0030.10.937696
MA0031.10.871496
MA0038.10.665566
MA0040.10.955415
MA0041.10.578072
MA0042.10.544748
MA0043.11.03713
MA0046.11.02569
MA0048.10.152639
MA0050.10.545671
MA0051.10.661179
MA0052.10.959373
MA0055.10.213007
MA0056.10
MA0057.10.147053
MA0058.10.458909
MA0059.10.457555
MA0060.10.737586
MA0061.10.23892
MA0063.10
MA0066.10.66601
MA0067.11.35893
MA0068.10.199491
MA0069.11.02175
MA0070.11.01032
MA0071.10.625297
MA0072.11.00572
MA0073.10.00076337
MA0074.10.660398
MA0076.10.475586
MA0077.10.997832
MA0078.10.763954
MA0081.10.457725
MA0083.11.04447
MA0084.11.5477
MA0087.11.00322
MA0088.11.09824
MA0089.10
MA0090.11.22966
MA0091.10.561458
MA0092.10.522012
MA0093.10.394379
MA0095.10
MA0098.10
MA0100.10.679972
MA0101.10.397846
MA0103.10.993014
MA0105.10.419295
MA0106.11.68738
MA0107.10.320267
MA0108.20.868347
MA0109.10
MA0111.10.504913
MA0113.10.725375
MA0114.10.314898
MA0115.11.28169
MA0116.10.323925
MA0117.11.07516
MA0119.10.440684
MA0122.11.10154
MA0124.11.23968
MA0125.11.15445
MA0130.10
MA0131.10.782708
MA0132.10
MA0133.10
MA0135.11.06778
MA0136.10.672893
MA0139.11.86787
MA0140.10.622527
MA0141.12.01346
MA0142.10.838805
MA0143.10.725558
MA0144.10.299851
MA0145.11.16614
MA0146.10.093337
MA0147.10.327615
MA0148.10.584698
MA0149.10.612449
MA0062.20.23336
MA0035.20.621793
MA0039.20.200862
MA0138.20.765223
MA0002.20.255126
MA0137.21.06611
MA0104.20.26661
MA0047.20.695777
MA0112.20.332548
MA0065.20.109623
MA0150.10.484557
MA0151.10
MA0152.10.629368
MA0153.11.13732
MA0154.10.132326
MA0155.11.09123
MA0156.10.417278
MA0157.10.810597
MA0158.10
MA0159.12.38949
MA0160.10.600559
MA0161.10
MA0162.10.0383129
MA0163.10.0270301
MA0164.10.738243
MA0080.20.394469
MA0018.20.709805
MA0099.20.629739
MA0079.20.0318308
MA0102.21.58513
MA0258.11.43672
MA0259.10.336472
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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