FF:10772-110F7: Difference between revisions
From FANTOM5_SSTAR
(Created page with "{{f5samples
|id=FF:10772-110F7
|name=myelodysplastic syndrome cell line:SKM-1, biol_rep1
|sample_id=10772
|rna_tube_id=110F7
|rna_box=110
|rna_position=F7
|sample_cell_...") |
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00004747 | ||
| | |accession_numbers=CAGE;DRX007956;DRR008828;DRZ000253;DRZ001638;DRZ011603;DRZ012988 | ||
| | |ancestors_in_anatomy_facet= | ||
|ancestors_in_cell_lineage_facet= | |ancestors_in_cell_lineage_facet= | ||
|ancestors_in_disease_facet=DOID:4,DOID:1287,DOID:7,DOID:74,DOID:225 | |||
|ancestors_in_disease_facet=DOID:1287,DOID: | |ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001 | ||
| | |comment= | ||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr11:47400078..47400106,-!p1@SPI1!2.21!160.36!SPI1;;chr2:68592406..68592424,+!p1@PLEK!2.13!132.83!PLEK;;chr6:135502501..135502546,+!p1@MYB!2.00!117.47!MYB;;chr6:135502408..135502459,+!p2@MYB!1.90!91.22!MYB;;chr21:34442439..34442455,+!p1@OLIG1!1.76!56.23!OLIG1;;chr1:92949331..92949377,-!p2@GFI1!1.62!40.86!GFI1;;chr7:50344289..50344323,+!p1@IKZF1!1.62!40.86!IKZF1;;chr3:18486354..18486377,-!p2@SATB1!1.49!37.24!SATB1;;chrX:103499602..103499617,-!p1@ESX1!1.49!29.98!ESX1;;chr1:92951607..92951661,-!p1@GFI1!1.49!29.66!GFI1;;chr7:27205136..27205164,-!p1@HOXA9!1.47!28.81!HOXA9;;chr19:33793430..33793447,-!p1@CEBPA!1.44!108.51!CEBPA;;chr11:47400062..47400077,-!p2@SPI1!1.44!26.78!SPI1;;chr7:27205106..27205134,-!p2@HOXA9!1.39!23.47!HOXA9;;chr21:34442540..34442560,+!p2@OLIG1!1.31!19.20!OLIG1;;chr14:75988771..75988826,+!p1@BATF!1.30!25.07!BATF;;chr12:54694758..54694805,-!p1@NFE2!1.29!22.41!NFE2;;chr16:85932760..85932775,+!p1@IRF8!1.27!17.60!IRF8;;chr6:135502472..135502489,+!p3@MYB!1.25!16.75!MYB;;chr2:60780607..60780624,-!p2@BCL11A!1.23!48.12!BCL11A;;chr12:54694807..54694832,-!p3@NFE2!1.23!16.00!NFE2;;chr20:42295745..42295765,+!p1@MYBL2!1.22!250.62!MYBL2;;chr11:32457075..32457095,-!p1@WT1!1.22!15.68!WT1;;chr22:19748231..19748317,+!p1@TBX1!1.22!15.68!TBX1;;chr7:50343634..50343717,+!p2@IKZF1!1.18!14.30!IKZF1;;chr7:137620650..137620677,-!p3@CREB3L2!1.17!13.87!CREB3L2;;chr2:145277640..145277771,-!p1@ZEB2!1.15!174.55!ZEB2;;chr1:167298300..167298319,+!p2@POU2F1!1.15!13.23!POU2F1;;chr9:96717629..96717644,-!p1@BARX1!1.15!13.12!BARX1;;chr20:50159198..50159299,-!p1@NFATC2!1.13!18.14!NFATC2;;chr7:113726357..113726443,+!p1@FOXP2!1.12!21.23!FOXP2;;chr20:42295713..42295738,+!p2@MYBL2!1.11!70.84!MYBL2;;chr7:137620684..137620711,-!p4@CREB3L2!1.11!11.74!CREB3L2;;chr10:94449703..94449718,+!p1@HHEX!1.10!45.24!HHEX;;chr13:41593425..41593480,-!p1@ELF1!1.09!71.91!ELF1;;chr1:92952473..92952489,-!p3@GFI1!1.09!11.20!GFI1;;chrX:103499660..103499666,-!p2@ESX1!1.09!11.20!ESX1;;chr10:31288398..31288455,-!p2@ZNF438!1.06!12.27!ZNF438;;chr21:36421535..36421610,-!p2@RUNX1!1.05!36.92!RUNX1;;chr19:13213662..13213686,-!p1@LYL1!1.05!15.36!LYL1;;chr11:47400032..47400043,-!p5@SPI1!1.05!10.35!SPI1;;chr11:47399947..47399961,-!p3@SPI1!1.03!9.71!SPI1;;chr12:54778471..54778528,-!p1@ZNF385A!1.03!9.71!ZNF385A;;chr19:12203100..12203132,+!p1@ZNF788!1.02!19.63!ZNF788;;chr11:31832658..31832681,-!p1@PAX6!1.01!9.18!PAX6;;chr11:47400045..47400060,-!p6@SPI1!0.99!8.75!SPI1;;chr2:239148671..239148686,-!p1@HES6!0.96!30.94!HES6;;chr1:156470515..156470542,-!p2@MEF2D!0.95!42.36!MEF2D;;chr17:41277372..41277418,-!p1@BRCA1!0.95!29.98!BRCA1;;chr16:54320617..54320643,-!p3@IRX3!0.94!10.14!IRX3;;chr8:145669791..145669834,-!p1@TONSL!0.93!22.41!TONSL;;chr15:76629123..76629151,+!p1@ISL2!0.93!8.43!ISL2;;chr7:50344251..50344288,+!p3@IKZF1!0.93!7.47!IKZF1;;chr11:128563948..128564003,+!p1@FLI1!0.92!92.72!FLI1;;chr6:126240380..126240430,+!p2@NCOA7!0.91!19.10!NCOA7;;chr19:22817119..22817145,+!p1@ZNF492!0.90!11.95!ZNF492;;chr11:47399996..47400014,-!p4@SPI1!0.89!6.72!SPI1;;chr2:60780753..60780800,-!p1@BCL11A!0.88!34.03!BCL11A;;chr16:54320646..54320672,-!p2@IRX3!0.88!10.35!IRX3;;chr7:27213893..27213954,-!p1@HOXA10!0.88!6.61!HOXA10;;chr1:92949505..92949543,-!p5@GFI1!0.88!6.51!GFI1;;chr2:185463247..185463263,+!p1@ZNF804A!0.87!11.74!ZNF804A;;chr16:54320158..54320200,-!p5@IRX3!0.87!9.50!IRX3;;chr2:60778035..60778060,-!p4@BCL11A!0.87!7.68!BCL11A;;chr6:15246200..15246214,+!p2@JARID2!0.85!17.50!JARID2;;chr12:11802547..11802560,+!p5@ETV6!0.85!8.64!ETV6;;chr6:144385698..144385742,-!p2@PLAGL1!0.85!7.58!PLAGL1;;chr2:200320768..200320800,-!p4@SATB2!0.85!6.08!SATB2;;chr6:20402102..20402152,+!p1@E2F3!0.84!26.03!E2F3;;chr6:126240442..126240459,+!p4@NCOA7!0.84!7.79!NCOA7;;chr7:27196267..27196311,-!p1@HOXA7!0.84!5.97!HOXA7;;chr11:6947720..6947812,+!p1@ZNF215!0.83!7.68!ZNF215;;chr7:115670804..115670825,-!p1@TFEC!0.82!5.65!TFEC;;chr16:54320675..54320715,-!p1@IRX3!0.81!12.27!IRX3;;chr10:101292684..101292706,+!p1@NKX2-3!0.80!5.33!NKX2-3;;chr10:131762504..131762555,-!p1@EBF3!0.80!5.33!EBF3;;chr2:208031943..208031978,-!p5@KLF7!0.79!7.15!KLF7;;chr2:60781201..60781258,-!p3@BCL11A!0.79!5.23!BCL11A;;chr16:54320322..54320343,-!p7@IRX3!0.78!5.01!IRX3;;chr11:19262461..19262476,-!p5@E2F8!0.78!5.01!E2F8;;chrX:66763856..66763896,+!p1@AR!0.77!7.26!AR;;chr2:68592394..68592405,+!p2@PLEK!0.77!4.91!PLEK;;chr17:41623692..41623715,-!p1@ETV4!0.76!22.19!ETV4;;chrX:101186981..101187030,-!p1@ZMAT1!0.76!16.96!ZMAT1;;chr10:94449675..94449694,+!p2@HHEX!0.76!13.76!HHEX;;chr6:126240463..126240489,+!p6@NCOA7!0.76!5.44!NCOA7;;chr19:13213511..13213545,-!p2@LYL1!0.76!5.23!LYL1;;chr13:36871902..36872023,-!p1@CCDC169-SOHLH2,p1@CCDC169,p1@SOHLH2!0.75!10.67!SOHLH2;;chr1:25256756..25256774,-!p1@RUNX3!0.75!9.28!RUNX3;;chr2:200322654..200322707,-!p2@SATB2!0.75!6.93!SATB2;;chr3:128206762..128206781,-!p2@GATA2!0.74!31.15!GATA2;;chr11:19262486..19262512,-!p4@E2F8!0.74!5.76!E2F8;;chr6:135516877..135516900,+!p5@MYB!0.74!4.48!MYB;;chr21:36421518..36421532,-!p11@RUNX1!0.74!4.48!RUNX1;;chr1:247171347..247171366,-!p2@ZNF695!0.73!8.54!ZNF695;;chr2:145277882..145277967,-!p3@ZEB2!0.72!7.90!ZEB2;;chr8:128747661..128747703,+!p6@MYC!0.71!5.76!MYC;;chr11:19263160..19263176,-!p1@E2F8!0.71!5.01!E2F8;;chr11:32457103..32457123,-!p3@WT1!0.71!4.16!WT1;;chr17:48046543..48046575,+!p2@DLX4!0.71!4.16!DLX4;;chr8:128748470..128748487,+!p1@MYC!0.70!501.34!MYC;;chr8:123793708..123793723,+!p6@ZHX2!0.70!4.05!ZHX2;;chr14:37131058..37131139,+!p1@PAX9!0.70!4.05!PAX9;;chr1:167298384..167298412,+!p3@POU2F1!0.70!4.05!POU2F1;;chr2:100759037..100759058,-!p2@AFF3!0.70!4.05!AFF3;;chr20:32274179..32274213,-!p1@E2F1!0.69!29.34!E2F1;;chr7:64126535..64126559,+!p2@ZNF107!0.69!9.07!ZNF107;;chr7:27135591..27135658,-!p1@HOXA1!0.69!8.11!HOXA1;;chr11:113930425..113930471,+!p1@ZBTB16!0.69!5.87!ZBTB16;;chr17:42295777..42295816,-!p7@UBTF!0.69!4.80!UBTF;;chr16:54320280..54320291,-!p9@IRX3!0.69!3.95!IRX3;;chr10:31146697..31146708,-!p11@ZNF438!0.69!3.95!ZNF438;;chr1:247171316..247171336,-!p3@ZNF695!0.68!5.97!ZNF695;;chr12:54694653..54694672,-!p2@NFE2!0.68!3.84!NFE2;;chr7:27224842..27224872,-!p1@HOXA11!0.68!3.73!HOXA11;;chr2:63277948..63277974,+!p1@OTX1!0.68!3.73!OTX1;;chr14:55493763..55493824,-!p1@WDHD1!0.67!32.11!WDHD1;;chr6:15246217..15246228,+!p3@JARID2!0.67!7.04!JARID2;;chr2:102091566..102091581,-!p1@RFX8!0.67!3.63!RFX8;;chr10:31146746..31146755,-!p14@ZNF438!0.67!3.63!ZNF438;;chr11:19262421..19262455,-!p3@E2F8!0.67!3.63!E2F8;;chr1:151319710..151319774,-!p1@RFX5!0.66!40.65!RFX5;;chr6:31126291..31126399,+!p1@TCF19!0.66!39.05!TCF19;;chr6:126240356..126240379,+!p7@NCOA7!0.66!4.48!NCOA7;;chr11:47399920..47399931,-!p7@SPI1!0.66!3.52!SPI1;;chr16:54319010..54319041,-!p8@IRX3!0.66!3.52!IRX3;;chr5:176738887..176738934,-!p1@MXD3!0.65!26.89!MXD3;;chr15:41913690..41913753,+!p2@MGA!0.65!9.39!MGA;;chr1:221052994..221053008,+!p6@HLX!0.65!4.27!HLX;;chr18:77155922..77155939,+!p1@NFATC1!0.64!10.46!NFATC1;;chr18:6414884..6414942,-!p1@L3MBTL4!0.64!4.37!L3MBTL4;;chr3:71631151..71631194,-!p15@FOXP1!0.64!3.84!FOXP1;;chr19:10416315..10416333,-!p1@ZGLP1!0.64!3.41!ZGLP1;;chr19:13213954..13214021,-!p4@LYL1!0.64!3.41!LYL1;;chr3:126076264..126076305,-!p2@KLF15!0.63!4.80!KLF15;;chr1:227751231..227751273,+!p1@ZNF678!0.62!23.58!ZNF678;;chr17:46655730..46655791,-!p1@HOXB4!0.62!8.86!HOXB4;;chr1:156470494..156470505,-!p3@MEF2D!0.62!4.91!MEF2D;;chr6:28304275..28304282,-!p7@ZNF323!0.62!3.20!ZNF323;;chr8:128748308..128748324,+!p2@MYC!0.61!102.64!MYC;;chr1:247242048..247242098,-!p1@ZNF670,p1@ZNF695!0.61!12.91!ZNF670;;chr6:126102254..126102289,+!p5@NCOA7!0.61!9.82!NCOA7;;chrX:84499081..84499115,+!p2@ZNF711!0.61!4.91!ZNF711;;chr6:135513595..135513617,+!p4@MYB!0.61!3.09!MYB;;chr17:48045917..48045977,+!p1@DLX4!0.61!3.09!DLX4;;chr18:55102598..55102623,+!p1@ONECUT2!0.61!3.09!ONECUT2;;chr18:56940611..56940660,-!p1@RAX!0.61!3.09!RAX;;chr6:15246261..15246312,+!p1@JARID2!0.60!87.81!JARID2;;chr14:45722360..45722415,-!p1@MIS18BP1!0.60!56.65!MIS18BP1;;chr8:124286495..124286548,-!p1@ZHX1!0.60!35.42!ZHX1;;chr2:200322229..200322251,-!p3@SATB2!0.60!2.99!SATB2;;chr19:10305581..10305646,-!p1@DNMT1!0.59!124.40!DNMT1;;chr19:12203069..12203094,+!p2@ZNF788!0.59!4.59!ZNF788;;chr16:54320101..54320125,-!p4@IRX3!0.59!4.48!IRX3;;chr8:128747757..128747800,+!p7@MYC!0.59!4.16!MYC;;chr7:27190547..27190591,-!p1@HOXA6!0.59!2.88!HOXA6;;chr7:50348268..50348366,+!p4@IKZF1!0.59!2.88!IKZF1;;chr2:172949484..172949522,+!p1@DLX1!0.59!2.88!DLX1;;chr2:42721205..42721307,+!p4@MTA3!0.59!2.88!MTA3;;chr21:36260980..36261011,-!p1@RUNX1!0.58!100.50!RUNX1;;chr6:34204973..34204990,+!p4@HMGA1!0.58!45.45!HMGA1;;chr7:64126503..64126528,+!p1@ZNF107!0.58!24.01!ZNF107;;chr9:20622444..20622468,-!p2@MLLT3!0.58!10.56!MLLT3;;chrX:131623932..131623964,-!p7@MBNL3!0.58!4.37!MBNL3;;chr4:87857491..87857519,+!p10@AFF1!0.58!4.16!AFF1;;chrX:66763815..66763854,+!p2@AR!0.57!3.84!AR;;chr17:42295897..42295953,-!p10@UBTF!0.57!3.84!UBTF;;chr1:153940354..153940395,+!p1@CREB3L4!0.56!12.91!CREB3L4;;chr11:130184470..130184533,-!p2@ZBTB44!0.56!8.54!ZBTB44;;chr19:12163769..12163798,-!p1@ZNF878!0.56!3.63!ZNF878;;chr1:167298425..167298440,+!p8@POU2F1!0.56!2.67!POU2F1;;chr6:135516909..135516925,+!p6@MYB!0.56!2.67!MYB;;chr10:111967345..111967422,+!p1@MXI1!0.55!52.71!MXI1;;chr6:144329500..144329526,-!p4@PLAGL1!0.55!6.93!PLAGL1;;chr19:925727..925784,+!p3@ARID3A!0.55!6.29!ARID3A;;chr19:13213704..13213726,-!p3@LYL1!0.55!3.63!LYL1;;chr17:46675420..46675465,-!p3@HOXB6!0.55!3.09!HOXB6;;chr1:3569072..3569093,+!p1@TP73!0.55!2.56!TP73;;chr2:60778062..60778075,-!p6@BCL11A!0.55!2.56!BCL11A;;chr6:135516978..135516993,+!p7@MYB!0.55!2.56!MYB;;chr7:27224795..27224840,-!p2@HOXA11!0.55!2.56!HOXA11;;chr10:31288370..31288393,-!p3@ZNF438!0.55!2.56!ZNF438;;chr14:23588242..23588262,-!p1@CEBPE!0.55!2.56!CEBPE;;chr4:4291837..4291859,-!p2@LYAR!0.54!9.71!LYAR;;chr14:45722287..45722308,-!p2@MIS18BP1!0.54!7.79!MIS18BP1;;chr1:221052733..221052749,+!p2@HLX!0.54!3.41!HLX;;chr18:55102628..55102646,+!p2@ONECUT2!0.54!2.45!ONECUT2;;chr5:359596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| |||
|fonse_cell_line=FF:10772-110F7 | |fonse_cell_line=FF:10772-110F7 | ||
|fonse_cell_line_closure=FF:10772-110F7 | |fonse_cell_line_closure=FF:10772-110F7 | ||
Line 67: | Line 39: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/myelodysplastic%2520syndrome%2520cell%2520line%253aSKM-1.CNhs11934.10772-110F7.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/myelodysplastic%2520syndrome%2520cell%2520line%253aSKM-1.CNhs11934.10772-110F7.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/myelodysplastic%2520syndrome%2520cell%2520line%253aSKM-1.CNhs11934.10772-110F7.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/myelodysplastic%2520syndrome%2520cell%2520line%253aSKM-1.CNhs11934.10772-110F7.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/myelodysplastic%2520syndrome%2520cell%2520line%253aSKM-1.CNhs11934.10772-110F7.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10772-110F7 | |||
|is_a=DOID:225;;DOID:74;;EFO:0002091;;FF:0000003;;FF:0000210 | |||
|is_obsolete= | |||
|library_id=CNhs11934 | |||
|library_id_phase_based=2:CNhs11934 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10772 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10772 | |||
|name=myelodysplastic syndrome cell line:SKM-1 | |||
|namespace=FANTOM5 | |||
|part_of= | |||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs11934,LSID835,release010,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
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| |||
|rna_box=110 | |||
|rna_catalog_number= | |||
|rna_concentration=0.34839 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=1.83 | |||
|rna_od260/280=2.05 | |||
|rna_position=F7 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=110F7 | |||
|rna_weight_ug=9.40653 | |||
|sample_age=76 | |||
|sample_category=cell lines | |||
|sample_cell_catalog=jcrb0118 | |||
|sample_cell_line=SKM-1 | |||
|sample_cell_lot= | |||
|sample_cell_type=myeloid cell | |||
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest) | |||
|sample_company=JAPAN HEALTH SCIENCES FOUNDATION - Health Science Research Resources Bank | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=myelodysplastic syndrome | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=unknown | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.26360276383513e-273!GO:0043227;membrane-bound organelle;6.51999734238663e-238!GO:0043231;intracellular membrane-bound organelle;1.47191018392344e-237!GO:0043226;organelle;8.27197155141158e-227!GO:0043229;intracellular organelle;2.35572983053277e-226!GO:0005737;cytoplasm;1.73444436061887e-174!GO:0044422;organelle part;1.29197322570608e-163!GO:0044446;intracellular organelle part;1.00091040202469e-161!GO:0044444;cytoplasmic part;8.79023129108369e-125!GO:0044237;cellular metabolic process;8.19523874869216e-120!GO:0044238;primary metabolic process;1.16384694065851e-116!GO:0005634;nucleus;7.41332823561813e-115!GO:0032991;macromolecular complex;3.03525536474505e-114!GO:0043170;macromolecule metabolic process;1.07667158175981e-107!GO:0030529;ribonucleoprotein complex;1.89307734758558e-101!GO:0044428;nuclear part;1.68082060195261e-97!GO:0043233;organelle lumen;6.52882879566915e-91!GO:0031974;membrane-enclosed lumen;6.52882879566915e-91!GO:0003723;RNA binding;7.44077940605753e-90!GO:0005739;mitochondrion;7.00471150137345e-81!GO:0043283;biopolymer metabolic process;9.60251319748813e-69!GO:0006396;RNA processing;2.47391013845358e-65!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.49300580621311e-64!GO:0006412;translation;2.6406329078189e-62!GO:0010467;gene expression;2.10932157205765e-61!GO:0005515;protein binding;3.83099905951196e-59!GO:0005840;ribosome;1.76868920576954e-58!GO:0031981;nuclear lumen;1.34088556607581e-56!GO:0043234;protein complex;4.14305340985824e-56!GO:0044429;mitochondrial part;1.43102662219173e-55!GO:0009058;biosynthetic process;1.63115008282265e-51!GO:0003735;structural constituent of ribosome;8.60123378675032e-51!GO:0019538;protein metabolic process;1.3203245919716e-50!GO:0006259;DNA metabolic process;1.0566630386722e-49!GO:0016071;mRNA metabolic process;1.39808914148926e-49!GO:0044249;cellular biosynthetic process;2.01665474094854e-49!GO:0031975;envelope;2.23152712957917e-49!GO:0031967;organelle envelope;3.38077934307664e-49!GO:0031090;organelle membrane;9.73814632281617e-49!GO:0016043;cellular component organization and biogenesis;1.13205785699952e-48!GO:0009059;macromolecule biosynthetic process;1.23868693679696e-48!GO:0044260;cellular macromolecule metabolic process;1.16955781789085e-45!GO:0044267;cellular protein metabolic process;1.19346377375977e-45!GO:0008380;RNA splicing;1.9867128248022e-44!GO:0033036;macromolecule localization;1.58167488628363e-43!GO:0006397;mRNA processing;2.64073183429371e-43!GO:0033279;ribosomal subunit;5.29873970595126e-43!GO:0015031;protein transport;9.20279855832009e-42!GO:0006996;organelle organization and biogenesis;1.36218399568518e-40!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.36218399568518e-40!GO:0003676;nucleic acid binding;3.06862403947264e-40!GO:0045184;establishment of protein localization;3.59401787574423e-39!GO:0008104;protein localization;7.98701826864792e-39!GO:0007049;cell cycle;4.97872692854325e-38!GO:0043228;non-membrane-bound organelle;6.61746773441338e-37!GO:0043232;intracellular non-membrane-bound organelle;6.61746773441338e-37!GO:0065003;macromolecular complex assembly;1.47271704278598e-36!GO:0005654;nucleoplasm;2.38756292055731e-35!GO:0005829;cytosol;8.89935071243966e-35!GO:0046907;intracellular transport;2.89642313314615e-34!GO:0005740;mitochondrial envelope;3.53021161862074e-34!GO:0019866;organelle inner membrane;3.127786347204e-33!GO:0005681;spliceosome;5.85778845759953e-33!GO:0031966;mitochondrial membrane;9.69762789730367e-33!GO:0005694;chromosome;1.94092579227298e-32!GO:0022607;cellular component assembly;7.85151825559572e-32!GO:0005743;mitochondrial inner membrane;1.79512324209534e-30!GO:0006886;intracellular protein transport;3.41039732956206e-30!GO:0022402;cell cycle process;4.47102175767658e-30!GO:0005830;cytosolic ribosome (sensu Eukaryota);5.23596175477739e-30!GO:0000166;nucleotide binding;6.2544616374135e-30!GO:0016070;RNA metabolic process;4.21279067072499e-29!GO:0006974;response to DNA damage stimulus;1.07292430211741e-28!GO:0044427;chromosomal part;3.42390381895992e-28!GO:0044451;nucleoplasm part;5.35828059737147e-28!GO:0006281;DNA repair;8.77574364059621e-27!GO:0051649;establishment of cellular localization;2.48406038474252e-26!GO:0000278;mitotic cell cycle;6.59857886321898e-26!GO:0044445;cytosolic part;7.43436445501154e-26!GO:0051641;cellular localization;8.6159856183944e-26!GO:0031980;mitochondrial lumen;1.5406582064222e-25!GO:0005759;mitochondrial matrix;1.5406582064222e-25!GO:0051276;chromosome organization and biogenesis;1.10995232309521e-23!GO:0006119;oxidative phosphorylation;3.20434776487766e-23!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;2.08310628393299e-22!GO:0016817;hydrolase activity, acting on acid anhydrides;2.37293927011971e-22!GO:0016462;pyrophosphatase activity;3.09227244551687e-22!GO:0015935;small ribosomal subunit;3.37769306289963e-22!GO:0022403;cell cycle phase;3.52187373538047e-22!GO:0016874;ligase activity;3.52187373538047e-22!GO:0051301;cell division;3.77573566934549e-22!GO:0044455;mitochondrial membrane part;5.41560750008703e-22!GO:0015934;large ribosomal subunit;8.15974012764623e-22!GO:0022618;protein-RNA complex assembly;2.3459928131938e-21!GO:0032553;ribonucleotide binding;4.93293803259044e-21!GO:0032555;purine ribonucleotide binding;4.93293803259044e-21!GO:0005730;nucleolus;6.25092402709193e-21!GO:0017076;purine nucleotide binding;1.217682036106e-20!GO:0044265;cellular macromolecule catabolic process;1.9949002361433e-20!GO:0017111;nucleoside-triphosphatase activity;2.24294437908416e-20!GO:0000087;M phase of mitotic cell cycle;2.70366115689873e-20!GO:0042254;ribosome biogenesis and assembly;4.26062682194847e-20!GO:0007067;mitosis;7.26687665958187e-20!GO:0005524;ATP binding;1.23818135071546e-19!GO:0006457;protein folding;2.29550836174117e-19!GO:0032559;adenyl ribonucleotide binding;2.86436942497838e-19!GO:0043285;biopolymer catabolic process;4.59635266563015e-19!GO:0009719;response to endogenous stimulus;1.09805941791749e-18!GO:0006260;DNA replication;1.14501077706769e-18!GO:0030554;adenyl nucleotide binding;1.14760991574512e-18!GO:0012505;endomembrane system;1.68842318379018e-18!GO:0000279;M phase;2.28876823426118e-18!GO:0006325;establishment and/or maintenance of chromatin architecture;3.71188996976516e-18!GO:0005761;mitochondrial ribosome;7.29314598266442e-18!GO:0000313;organellar ribosome;7.29314598266442e-18!GO:0009057;macromolecule catabolic process;1.4122023771208e-17!GO:0006323;DNA packaging;1.80154130662297e-17!GO:0005746;mitochondrial respiratory chain;2.59685925488388e-17!GO:0006512;ubiquitin cycle;2.66978188211175e-17!GO:0051603;proteolysis involved in cellular protein catabolic process;2.85908524940238e-17!GO:0019941;modification-dependent protein catabolic process;3.55882097250861e-17!GO:0043632;modification-dependent macromolecule catabolic process;3.55882097250861e-17!GO:0044248;cellular catabolic process;3.92630696432401e-17!GO:0006511;ubiquitin-dependent protein catabolic process;6.98915165009911e-17!GO:0008135;translation factor activity, nucleic acid binding;7.47361106101218e-17!GO:0044257;cellular protein catabolic process;8.62584578358353e-17!GO:0000502;proteasome complex (sensu Eukaryota);8.78777857858796e-17!GO:0048770;pigment granule;9.73166899839793e-17!GO:0042470;melanosome;9.73166899839793e-17!GO:0051186;cofactor metabolic process;1.48537626531292e-16!GO:0006605;protein targeting;4.59477158501603e-16!GO:0000398;nuclear mRNA splicing, via spliceosome;6.46943426475475e-16!GO:0000375;RNA splicing, via transesterification reactions;6.46943426475475e-16!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;6.46943426475475e-16!GO:0016887;ATPase activity;9.65121500953837e-16!GO:0008134;transcription factor binding;1.25089331709026e-15!GO:0042623;ATPase activity, coupled;1.2625906054814e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.32612864829238e-15!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;1.64400754338743e-15!GO:0005635;nuclear envelope;1.85264839912341e-15!GO:0043412;biopolymer modification;2.32565120764884e-15!GO:0044453;nuclear membrane part;3.35825849536989e-15!GO:0050136;NADH dehydrogenase (quinone) activity;3.99203737977711e-15!GO:0003954;NADH dehydrogenase activity;3.99203737977711e-15!GO:0008137;NADH dehydrogenase (ubiquinone) activity;3.99203737977711e-15!GO:0016604;nuclear body;4.21412570464769e-15!GO:0000785;chromatin;4.42385713874505e-15!GO:0051726;regulation of cell cycle;4.94185679536387e-15!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);6.66842692896419e-15!GO:0000074;regulation of progression through cell cycle;1.02171085394441e-14!GO:0031965;nuclear membrane;1.11550896734586e-14!GO:0030163;protein catabolic process;1.28575579042805e-14!GO:0044432;endoplasmic reticulum part;1.68678008736282e-14!GO:0006399;tRNA metabolic process;1.90194346154938e-14!GO:0050657;nucleic acid transport;2.56879468299284e-14!GO:0051236;establishment of RNA localization;2.56879468299284e-14!GO:0050658;RNA transport;2.56879468299284e-14!GO:0006913;nucleocytoplasmic transport;3.05064833411546e-14!GO:0006403;RNA localization;3.94166528037417e-14!GO:0004386;helicase activity;4.57044678163045e-14!GO:0006364;rRNA processing;4.86636467711811e-14!GO:0051082;unfolded protein binding;6.41664764925445e-14!GO:0006732;coenzyme metabolic process;6.67438557673851e-14!GO:0051169;nuclear transport;7.21082704827193e-14!GO:0042775;organelle ATP synthesis coupled electron transport;1.0812111656014e-13!GO:0042773;ATP synthesis coupled electron transport;1.0812111656014e-13!GO:0016072;rRNA metabolic process;1.78824352140415e-13!GO:0006413;translational initiation;1.80295595943727e-13!GO:0006333;chromatin assembly or disassembly;1.90936327523758e-13!GO:0005783;endoplasmic reticulum;2.06087995009241e-13!GO:0003743;translation initiation factor activity;2.28772377404773e-13!GO:0005643;nuclear pore;2.89092363106982e-13!GO:0030964;NADH dehydrogenase complex (quinone);3.00450341065668e-13!GO:0045271;respiratory chain complex I;3.00450341065668e-13!GO:0005747;mitochondrial respiratory chain complex I;3.00450341065668e-13!GO:0006464;protein modification process;6.23165290896278e-13!GO:0009259;ribonucleotide metabolic process;6.77004173076192e-13!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;9.54022169272267e-13!GO:0006446;regulation of translational initiation;1.44063739986768e-12!GO:0065002;intracellular protein transport across a membrane;1.47897299572504e-12!GO:0006163;purine nucleotide metabolic process;2.44223608931823e-12!GO:0065004;protein-DNA complex assembly;2.85402701840743e-12!GO:0006915;apoptosis;3.58416207219091e-12!GO:0051028;mRNA transport;3.72838316352127e-12!GO:0012501;programmed cell death;3.98019285436922e-12!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;6.22223905686154e-12!GO:0000775;chromosome, pericentric region;6.93598533207783e-12!GO:0016607;nuclear speck;7.0613861730593e-12!GO:0008026;ATP-dependent helicase activity;7.43057295761353e-12!GO:0016568;chromatin modification;8.14630024299094e-12!GO:0009260;ribonucleotide biosynthetic process;1.12627244700992e-11!GO:0006164;purine nucleotide biosynthetic process;1.14518329678698e-11!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.53576492067466e-11!GO:0009150;purine ribonucleotide metabolic process;2.58776909474681e-11!GO:0005789;endoplasmic reticulum membrane;2.72266984548204e-11!GO:0016192;vesicle-mediated transport;2.89926148236408e-11!GO:0016787;hydrolase activity;8.58334048688308e-11!GO:0043687;post-translational protein modification;8.66978097680893e-11!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;9.36228317897947e-11!GO:0008219;cell death;1.17755602012883e-10!GO:0016265;death;1.17755602012883e-10!GO:0009152;purine ribonucleotide biosynthetic process;1.23023103345917e-10!GO:0046930;pore complex;1.26458001757108e-10!GO:0009056;catabolic process;1.37423392545236e-10!GO:0017038;protein import;1.78668356823671e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.9112048861208e-10!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;2.6198218443438e-10!GO:0004812;aminoacyl-tRNA ligase activity;2.6198218443438e-10!GO:0016875;ligase activity, forming carbon-oxygen bonds;2.6198218443438e-10!GO:0016879;ligase activity, forming carbon-nitrogen bonds;3.37300322267321e-10!GO:0008565;protein transporter activity;4.45226208895927e-10!GO:0043038;amino acid activation;4.45427160341168e-10!GO:0006418;tRNA aminoacylation for protein translation;4.45427160341168e-10!GO:0043039;tRNA aminoacylation;4.45427160341168e-10!GO:0051188;cofactor biosynthetic process;4.70976372016225e-10!GO:0009060;aerobic respiration;5.04104894622159e-10!GO:0016740;transferase activity;8.1153656790734e-10!GO:0003712;transcription cofactor activity;1.06067104347476e-09!GO:0048193;Golgi vesicle transport;1.06462780012625e-09!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.15295635452421e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;1.95383262302902e-09!GO:0043566;structure-specific DNA binding;1.9736343765658e-09!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.97958031764618e-09!GO:0006334;nucleosome assembly;2.32122831291633e-09!GO:0016779;nucleotidyltransferase activity;2.33182937943396e-09!GO:0006366;transcription from RNA polymerase II promoter;2.34071265753368e-09!GO:0050794;regulation of cellular process;2.80703112353286e-09!GO:0030532;small nuclear ribonucleoprotein complex;3.24347880828895e-09!GO:0008639;small protein conjugating enzyme activity;3.6593358046167e-09!GO:0031497;chromatin assembly;3.6593358046167e-09!GO:0045333;cellular respiration;5.39895107409058e-09!GO:0006261;DNA-dependent DNA replication;5.92814959627709e-09!GO:0009199;ribonucleoside triphosphate metabolic process;6.67618372890185e-09!GO:0015986;ATP synthesis coupled proton transport;7.38384862001799e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;7.38384862001799e-09!GO:0009141;nucleoside triphosphate metabolic process;7.81964787573544e-09!GO:0006461;protein complex assembly;8.39241077034438e-09!GO:0005794;Golgi apparatus;8.88251613999493e-09!GO:0051246;regulation of protein metabolic process;9.64281107031047e-09!GO:0019829;cation-transporting ATPase activity;9.77651862464347e-09!GO:0004842;ubiquitin-protein ligase activity;1.02488951812113e-08!GO:0009142;nucleoside triphosphate biosynthetic process;1.21668433607915e-08!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.21668433607915e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;1.45174024480109e-08!GO:0009144;purine nucleoside triphosphate metabolic process;1.45174024480109e-08!GO:0003697;single-stranded DNA binding;1.52529365270825e-08!GO:0019787;small conjugating protein ligase activity;1.56674799704258e-08!GO:0007005;mitochondrion organization and biogenesis;1.8170115256992e-08!GO:0005819;spindle;2.13336095777774e-08!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;2.77674195918165e-08!GO:0009145;purine nucleoside triphosphate biosynthetic process;2.77674195918165e-08!GO:0009108;coenzyme biosynthetic process;2.89179190129274e-08!GO:0009055;electron carrier activity;2.9710429596309e-08!GO:0005839;proteasome core complex (sensu Eukaryota);3.58146980326326e-08!GO:0006099;tricarboxylic acid cycle;5.251845796866e-08!GO:0046356;acetyl-CoA catabolic process;5.251845796866e-08!GO:0007051;spindle organization and biogenesis;6.32333774787361e-08!GO:0005768;endosome;6.83891913991386e-08!GO:0009117;nucleotide metabolic process;7.59951480425895e-08!GO:0046034;ATP metabolic process;8.71493205334814e-08!GO:0019222;regulation of metabolic process;8.77013287364378e-08!GO:0005657;replication fork;9.9282662543363e-08!GO:0006084;acetyl-CoA metabolic process;1.10009428831296e-07!GO:0015078;hydrogen ion transmembrane transporter activity;1.11560783901274e-07!GO:0051329;interphase of mitotic cell cycle;1.13442034072645e-07!GO:0006754;ATP biosynthetic process;1.28110968171009e-07!GO:0006753;nucleoside phosphate metabolic process;1.28110968171009e-07!GO:0000245;spliceosome assembly;1.29160211349984e-07!GO:0051325;interphase;1.31113998042344e-07!GO:0003899;DNA-directed RNA polymerase activity;1.36972275458058e-07!GO:0051170;nuclear import;1.3947045489813e-07!GO:0016881;acid-amino acid ligase activity;1.63013849008735e-07!GO:0009109;coenzyme catabolic process;1.65919551034668e-07!GO:0004298;threonine endopeptidase activity;2.00113348412381e-07!GO:0015630;microtubule cytoskeleton;2.28986123387339e-07!GO:0005813;centrosome;2.39520143322057e-07!GO:0005793;ER-Golgi intermediate compartment;2.73345883225241e-07!GO:0016469;proton-transporting two-sector ATPase complex;2.89968619638563e-07!GO:0006606;protein import into nucleus;3.56581212735194e-07!GO:0005815;microtubule organizing center;4.01082307596453e-07!GO:0000075;cell cycle checkpoint;4.0693110128324e-07!GO:0006752;group transfer coenzyme metabolic process;7.64395286437681e-07!GO:0003713;transcription coactivator activity;7.80879905723596e-07!GO:0051168;nuclear export;8.84839705741936e-07!GO:0008094;DNA-dependent ATPase activity;8.84839705741936e-07!GO:0045259;proton-transporting ATP synthase complex;8.89445518878259e-07!GO:0006793;phosphorus metabolic process;1.20442563941034e-06!GO:0006796;phosphate metabolic process;1.20442563941034e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.20691393695246e-06!GO:0051187;cofactor catabolic process;1.29905588842998e-06!GO:0005667;transcription factor complex;1.47655730063111e-06!GO:0042981;regulation of apoptosis;1.49667671187774e-06!GO:0016363;nuclear matrix;1.59367827694939e-06!GO:0006310;DNA recombination;1.97949975628687e-06!GO:0045786;negative regulation of progression through cell cycle;2.1717739465061e-06!GO:0003724;RNA helicase activity;2.22696249068186e-06!GO:0005762;mitochondrial large ribosomal subunit;2.3804365863772e-06!GO:0000315;organellar large ribosomal subunit;2.3804365863772e-06!GO:0043067;regulation of programmed cell death;2.62359506871123e-06!GO:0006302;double-strand break repair;2.77044489882079e-06!GO:0007059;chromosome segregation;3.0176367663454e-06!GO:0051427;hormone receptor binding;3.0177146409763e-06!GO:0006613;cotranslational protein targeting to membrane;3.41656340489954e-06!GO:0016741;transferase activity, transferring one-carbon groups;4.52564661796784e-06!GO:0000776;kinetochore;5.3468269969591e-06!GO:0048523;negative regulation of cellular process;5.63205796224533e-06!GO:0016563;transcription activator activity;5.85936055667374e-06!GO:0032446;protein modification by small protein conjugation;6.10361390617441e-06!GO:0008168;methyltransferase activity;6.22848465616095e-06!GO:0035257;nuclear hormone receptor binding;6.5639748315583e-06!GO:0008654;phospholipid biosynthetic process;7.10611036957633e-06!GO:0006401;RNA catabolic process;7.62502034519289e-06!GO:0003690;double-stranded DNA binding;8.03509683922978e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;8.03509683922978e-06!GO:0008033;tRNA processing;8.12146170905256e-06!GO:0031323;regulation of cellular metabolic process;8.23621986476602e-06!GO:0000786;nucleosome;8.51380337597941e-06!GO:0006888;ER to Golgi vesicle-mediated transport;1.08587044772653e-05!GO:0050789;regulation of biological process;1.08587044772653e-05!GO:0048475;coated membrane;1.13808623329562e-05!GO:0030117;membrane coat;1.13808623329562e-05!GO:0016567;protein ubiquitination;1.16666392039857e-05!GO:0004518;nuclease activity;1.16666392039857e-05!GO:0030120;vesicle coat;1.33270783822561e-05!GO:0030662;coated vesicle membrane;1.33270783822561e-05!GO:0005773;vacuole;1.39392909581061e-05!GO:0000323;lytic vacuole;1.49170672178403e-05!GO:0005764;lysosome;1.49170672178403e-05!GO:0003682;chromatin binding;1.7323401703091e-05!GO:0000314;organellar small ribosomal subunit;2.1199405361785e-05!GO:0005763;mitochondrial small ribosomal subunit;2.1199405361785e-05!GO:0000151;ubiquitin ligase complex;2.37127447081039e-05!GO:0005770;late endosome;2.68934081229378e-05!GO:0009165;nucleotide biosynthetic process;3.09218235501314e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;3.28587432869467e-05!GO:0043623;cellular protein complex assembly;3.5377151790559e-05!GO:0043021;ribonucleoprotein binding;4.02821243790483e-05!GO:0004527;exonuclease activity;4.05977084613067e-05!GO:0016310;phosphorylation;4.59493478701372e-05!GO:0006626;protein targeting to mitochondrion;5.01097215135557e-05!GO:0006383;transcription from RNA polymerase III promoter;5.35874358089212e-05!GO:0031324;negative regulation of cellular metabolic process;5.63638566847332e-05!GO:0006839;mitochondrial transport;5.68633098068409e-05!GO:0043681;protein import into mitochondrion;6.08999825628688e-05!GO:0006350;transcription;6.15421015336731e-05!GO:0044452;nucleolar part;6.16846247922879e-05!GO:0006916;anti-apoptosis;6.91943054657927e-05!GO:0006612;protein targeting to membrane;7.15496998311845e-05!GO:0006414;translational elongation;7.30083871169984e-05!GO:0032508;DNA duplex unwinding;7.93205472333506e-05!GO:0032392;DNA geometric change;7.93205472333506e-05!GO:0003678;DNA helicase activity;8.33939761992681e-05!GO:0019899;enzyme binding;8.35466862301482e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;8.42128251619616e-05!GO:0046489;phosphoinositide biosynthetic process;9.09534599549856e-05!GO:0008186;RNA-dependent ATPase activity;9.23069635899997e-05!GO:0003729;mRNA binding;9.2954075872026e-05!GO:0046474;glycerophospholipid biosynthetic process;0.000111320947951486!GO:0006950;response to stress;0.000113007378933941!GO:0048519;negative regulation of biological process;0.00011353929708254!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000115456012631182!GO:0006082;organic acid metabolic process;0.000124629038984066!GO:0006417;regulation of translation;0.000125818685608726!GO:0019752;carboxylic acid metabolic process;0.000125818685608726!GO:0010468;regulation of gene expression;0.000134084882533866!GO:0016853;isomerase activity;0.000138083829005251!GO:0005798;Golgi-associated vesicle;0.00013981855023837!GO:0000228;nuclear chromosome;0.000140278274540144!GO:0005788;endoplasmic reticulum lumen;0.000143743070831241!GO:0065009;regulation of a molecular function;0.000153414140124571!GO:0044440;endosomal part;0.000155037975515349!GO:0010008;endosome membrane;0.000155037975515349!GO:0005769;early endosome;0.000161291079196937!GO:0043069;negative regulation of programmed cell death;0.000161291079196937!GO:0030880;RNA polymerase complex;0.00016415307012518!GO:0006405;RNA export from nucleus;0.000169287331476583!GO:0015980;energy derivation by oxidation of organic compounds;0.00017093217543573!GO:0006268;DNA unwinding during replication;0.000173009961088381!GO:0016491;oxidoreductase activity;0.000178371408211944!GO:0043066;negative regulation of apoptosis;0.000179058757552779!GO:0006402;mRNA catabolic process;0.000190441045689974!GO:0007088;regulation of mitosis;0.000190441045689974!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.000193638654216444!GO:0015399;primary active transmembrane transporter activity;0.000193638654216444!GO:0007052;mitotic spindle organization and biogenesis;0.000197510428667846!GO:0031968;organelle outer membrane;0.000213807411210021!GO:0005525;GTP binding;0.000226140481347987!GO:0000082;G1/S transition of mitotic cell cycle;0.00023440465886117!GO:0005885;Arp2/3 protein complex;0.000262399634363308!GO:0009892;negative regulation of metabolic process;0.000263361475783096!GO:0019867;outer membrane;0.000272959477479351!GO:0030384;phosphoinositide metabolic process;0.000276606072484895!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00027807982748808!GO:0004004;ATP-dependent RNA helicase activity;0.000279621376127661!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000309901106035644!GO:0044431;Golgi apparatus part;0.000313141004302548!GO:0005741;mitochondrial outer membrane;0.00033318078162569!GO:0000049;tRNA binding;0.00034088325356193!GO:0003684;damaged DNA binding;0.000364196686514233!GO:0006352;transcription initiation;0.000365408791053151!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00036651756118934!GO:0000428;DNA-directed RNA polymerase complex;0.00036651756118934!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000373122591089437!GO:0016281;eukaryotic translation initiation factor 4F complex;0.000427124341661043!GO:0007006;mitochondrial membrane organization and biogenesis;0.000429941292735462!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000430867098964667!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.000462239397050718!GO:0000059;protein import into nucleus, docking;0.000466609831144384!GO:0006091;generation of precursor metabolites and energy;0.000466609831144384!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.00047988425578123!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000498978587731383!GO:0046483;heterocycle metabolic process;0.000512730692888372!GO:0031988;membrane-bound vesicle;0.000522834584889882!GO:0009124;nucleoside monophosphate biosynthetic process;0.00053321506965646!GO:0009123;nucleoside monophosphate metabolic process;0.00053321506965646!GO:0045454;cell redox homeostasis;0.000563430038853804!GO:0009112;nucleobase metabolic process;0.000591781335866798!GO:0016251;general RNA polymerase II transcription factor activity;0.000606838180204688!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.000606838180204688!GO:0016859;cis-trans isomerase activity;0.000609848733041481!GO:0051052;regulation of DNA metabolic process;0.000625445593884888!GO:0051539;4 iron, 4 sulfur cluster binding;0.000640081497089387!GO:0031326;regulation of cellular biosynthetic process;0.000653938645028282!GO:0006506;GPI anchor biosynthetic process;0.000666543106653987!GO:0016564;transcription repressor activity;0.000668361659338712!GO:0046467;membrane lipid biosynthetic process;0.00067677205324821!GO:0042802;identical protein binding;0.000689387383491685!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.000705802646640139!GO:0015992;proton transport;0.000729944365658693!GO:0006818;hydrogen transport;0.000767019685771244!GO:0006520;amino acid metabolic process;0.000787896724848193!GO:0006650;glycerophospholipid metabolic process;0.000791494034666503!GO:0005048;signal sequence binding;0.00081164994708336!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.000829293224343503!GO:0003924;GTPase activity;0.00083539113577288!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000880520944287646!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000880520944287646!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000880520944287646!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000900086896511054!GO:0000178;exosome (RNase complex);0.000921693530484265!GO:0008312;7S RNA binding;0.000955858383730503!GO:0008652;amino acid biosynthetic process;0.000970078583448617!GO:0048500;signal recognition particle;0.000972617817775711!GO:0051920;peroxiredoxin activity;0.00100462943679467!GO:0030867;rough endoplasmic reticulum membrane;0.00103170683546262!GO:0007093;mitotic cell cycle checkpoint;0.00103170683546262!GO:0006505;GPI anchor metabolic process;0.0010381604102957!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;0.0010498917470787!GO:0016023;cytoplasmic membrane-bound vesicle;0.00110064747013031!GO:0000792;heterochromatin;0.00110245046215365!GO:0031124;mRNA 3'-end processing;0.00112339832740285!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00113164297305562!GO:0031982;vesicle;0.00120141166048079!GO:0006611;protein export from nucleus;0.00128930076551337!GO:0006497;protein amino acid lipidation;0.00132085446443764!GO:0003746;translation elongation factor activity;0.00134426603817681!GO:0009161;ribonucleoside monophosphate metabolic process;0.00134546555831916!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.00134546555831916!GO:0005637;nuclear inner membrane;0.00134826992711418!GO:0004532;exoribonuclease activity;0.00137131276164287!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.00137131276164287!GO:0000287;magnesium ion binding;0.00141946280600767!GO:0043596;nuclear replication fork;0.00151029730686819!GO:0006284;base-excision repair;0.00151392445554158!GO:0005684;U2-dependent spliceosome;0.00168191628800802!GO:0008408;3'-5' exonuclease activity;0.00170514937764962!GO:0019843;rRNA binding;0.0017856204504825!GO:0042393;histone binding;0.00192496722013321!GO:0030521;androgen receptor signaling pathway;0.00194325169468872!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00205971031187013!GO:0045047;protein targeting to ER;0.00205971031187013!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00212854489304154!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00212854489304154!GO:0006270;DNA replication initiation;0.00222523144460171!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00225227511146569!GO:0015631;tubulin binding;0.00238648625028242!GO:0000139;Golgi membrane;0.002395205387534!GO:0006144;purine base metabolic process;0.00250276941016189!GO:0051252;regulation of RNA metabolic process;0.00252528785533115!GO:0004576;oligosaccharyl transferase activity;0.00252722987501932!GO:0003702;RNA polymerase II transcription factor activity;0.00253604324275365!GO:0007050;cell cycle arrest;0.00254673126169266!GO:0030663;COPI coated vesicle membrane;0.00254673126169266!GO:0030126;COPI vesicle coat;0.00254673126169266!GO:0009116;nucleoside metabolic process;0.00257360533657232!GO:0000819;sister chromatid segregation;0.00260411346933578!GO:0009889;regulation of biosynthetic process;0.00260598636340857!GO:0000922;spindle pole;0.00262896302679742!GO:0000070;mitotic sister chromatid segregation;0.00263830187003091!GO:0032561;guanyl ribonucleotide binding;0.0026641787673296!GO:0019001;guanyl nucleotide binding;0.0026641787673296!GO:0016272;prefoldin complex;0.00272029799809482!GO:0031410;cytoplasmic vesicle;0.00272422346346386!GO:0043284;biopolymer biosynthetic process;0.00273627387901326!GO:0006289;nucleotide-excision repair;0.00275295851619183!GO:0003711;transcription elongation regulator activity;0.00286370474465433!GO:0051540;metal cluster binding;0.00289676283258228!GO:0051536;iron-sulfur cluster binding;0.00289676283258228!GO:0016481;negative regulation of transcription;0.00290518845593747!GO:0035258;steroid hormone receptor binding;0.00296445712735479!GO:0006338;chromatin remodeling;0.00296985109315587!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00298118378330962!GO:0051087;chaperone binding;0.00300495325266542!GO:0046983;protein dimerization activity;0.00307341149762516!GO:0008250;oligosaccharyl transferase complex;0.00316100924801411!GO:0000910;cytokinesis;0.00317266438423791!GO:0043492;ATPase activity, coupled to movement of substances;0.00325430560332701!GO:0003677;DNA binding;0.00328635420746873!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00333370002634567!GO:0032774;RNA biosynthetic process;0.00335853234081917!GO:0031123;RNA 3'-end processing;0.00346681606037251!GO:0045045;secretory pathway;0.00349037728878702!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.00352159134633412!GO:0031072;heat shock protein binding;0.00360438735595021!GO:0000096;sulfur amino acid metabolic process;0.00365057307465535!GO:0047485;protein N-terminus binding;0.00368054725119853!GO:0050790;regulation of catalytic activity;0.00373235880105474!GO:0032200;telomere organization and biogenesis;0.00378344410025256!GO:0000723;telomere maintenance;0.00378344410025256!GO:0043601;nuclear replisome;0.00389345482021711!GO:0030894;replisome;0.00389345482021711!GO:0065007;biological regulation;0.0040445192147813!GO:0006378;mRNA polyadenylation;0.0040445192147813!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0040445192147813!GO:0008610;lipid biosynthetic process;0.0040445192147813!GO:0000097;sulfur amino acid biosynthetic process;0.00409391466208346!GO:0009451;RNA modification;0.00409820856380646!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00414374847149309!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00420730188189859!GO:0006351;transcription, DNA-dependent;0.00427247179905185!GO:0022890;inorganic cation transmembrane transporter activity;0.00429619876057937!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00439184382204806!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00445388473172582!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00460168761197215!GO:0044454;nuclear chromosome part;0.00466994476184933!GO:0000339;RNA cap binding;0.00469675816760769!GO:0007021;tubulin folding;0.00469675816760769!GO:0000725;recombinational repair;0.00469675816760769!GO:0000724;double-strand break repair via homologous recombination;0.00469675816760769!GO:0000726;non-recombinational repair;0.00484025345640659!GO:0004540;ribonuclease activity;0.00516240559053688!GO:0005758;mitochondrial intermembrane space;0.00521881352567773!GO:0044262;cellular carbohydrate metabolic process;0.005225349321746!GO:0042158;lipoprotein biosynthetic process;0.00560684874723521!GO:0030176;integral to endoplasmic reticulum membrane;0.00560684874723521!GO:0030658;transport vesicle membrane;0.00578042758737574!GO:0008632;apoptotic program;0.00581689742180362!GO:0003714;transcription corepressor activity;0.00582231938245599!GO:0050662;coenzyme binding;0.00582598990645067!GO:0030036;actin cytoskeleton organization and biogenesis;0.00582598990645067!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.00585775660857178!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.00585775660857178!GO:0009126;purine nucleoside monophosphate metabolic process;0.00585775660857178!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.00585775660857178!GO:0033116;ER-Golgi intermediate compartment membrane;0.00587401748629007!GO:0007034;vacuolar transport;0.00621743383510821!GO:0046966;thyroid hormone receptor binding;0.00660978471248021!GO:0031252;leading edge;0.00661819655534079!GO:0005876;spindle microtubule;0.00668243028862967!GO:0018196;peptidyl-asparagine modification;0.00696984419033805!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00696984419033805!GO:0005669;transcription factor TFIID complex;0.00696984419033805!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00705819007980766!GO:0022415;viral reproductive process;0.0070836408386028!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.00716052041707315!GO:0048471;perinuclear region of cytoplasm;0.00767260298722743!GO:0048522;positive regulation of cellular process;0.00776244713101441!GO:0031970;organelle envelope lumen;0.00802358901891132!GO:0000175;3'-5'-exoribonuclease activity;0.00810895118096558!GO:0043022;ribosome binding;0.00814718290862239!GO:0032259;methylation;0.00839714875674784!GO:0000118;histone deacetylase complex;0.00839714875674784!GO:0008022;protein C-terminus binding;0.00851624778220021!GO:0043065;positive regulation of apoptosis;0.00851624778220021!GO:0016044;membrane organization and biogenesis;0.0089723750787912!GO:0043488;regulation of mRNA stability;0.00912309086637616!GO:0043487;regulation of RNA stability;0.00912309086637616!GO:0008047;enzyme activator activity;0.00939112701980817!GO:0006406;mRNA export from nucleus;0.00943261371245334!GO:0016197;endosome transport;0.00946375613406917!GO:0006730;one-carbon compound metabolic process;0.0095440616811368!GO:0003725;double-stranded RNA binding;0.00979357223704315!GO:0051287;NAD binding;0.00985460567544329!GO:0006643;membrane lipid metabolic process;0.00988735983834615!GO:0005832;chaperonin-containing T-complex;0.00996520817774278!GO:0016311;dephosphorylation;0.00998026214876955!GO:0032940;secretion by cell;0.0100201985152545!GO:0048487;beta-tubulin binding;0.0100613666138594!GO:0006519;amino acid and derivative metabolic process;0.0100966651822082!GO:0045947;negative regulation of translational initiation;0.0100966651822082!GO:0004003;ATP-dependent DNA helicase activity;0.0102114472982352!GO:0046128;purine ribonucleoside metabolic process;0.0105795351761922!GO:0042278;purine nucleoside metabolic process;0.0105795351761922!GO:0016584;nucleosome positioning;0.0106009065306483!GO:0051053;negative regulation of DNA metabolic process;0.01066029427098!GO:0045449;regulation of transcription;0.0107068728293416!GO:0008180;signalosome;0.0108363562651822!GO:0006220;pyrimidine nucleotide metabolic process;0.0109511387678071!GO:0030137;COPI-coated vesicle;0.0109780319604186!GO:0031577;spindle checkpoint;0.0109851068067216!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0109990981510992!GO:0008139;nuclear localization sequence binding;0.0110249134628857!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0110249134628857!GO:0015002;heme-copper terminal oxidase activity;0.0110249134628857!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0110249134628857!GO:0004129;cytochrome-c oxidase activity;0.0110249134628857!GO:0030518;steroid hormone receptor signaling pathway;0.0111026628282874!GO:0006595;polyamine metabolic process;0.0111584993145608!GO:0000781;chromosome, telomeric region;0.0112674677730748!GO:0007040;lysosome organization and biogenesis;0.0112976226903368!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0114382416190104!GO:0043068;positive regulation of programmed cell death;0.0114404500782217!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0115824905665444!GO:0000152;nuclear ubiquitin ligase complex;0.0117826076627242!GO:0051789;response to protein stimulus;0.011957197194565!GO:0006986;response to unfolded protein;0.011957197194565!GO:0030660;Golgi-associated vesicle membrane;0.0121809796935499!GO:0006376;mRNA splice site selection;0.0126006699507835!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0126006699507835!GO:0000793;condensed chromosome;0.0127244906902785!GO:0016790;thiolester hydrolase activity;0.0129794927655347!GO:0031570;DNA integrity checkpoint;0.0133709356485555!GO:0016788;hydrolase activity, acting on ester bonds;0.0135297298977849!GO:0005663;DNA replication factor C complex;0.0135716367817057!GO:0022884;macromolecule transmembrane transporter activity;0.0135716367817057!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0135716367817057!GO:0016408;C-acyltransferase activity;0.0135716367817057!GO:0051098;regulation of binding;0.0136061785441929!GO:0006266;DNA ligation;0.0137040353105441!GO:0004674;protein serine/threonine kinase activity;0.0137906365964895!GO:0007017;microtubule-based process;0.01383692640666!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0139220594487545!GO:0008320;protein transmembrane transporter activity;0.0140217093428864!GO:0032984;macromolecular complex disassembly;0.0143633729548768!GO:0003923;GPI-anchor transamidase activity;0.0144281138106734!GO:0016255;attachment of GPI anchor to protein;0.0144281138106734!GO:0042765;GPI-anchor transamidase complex;0.0144281138106734!GO:0006516;glycoprotein catabolic process;0.0146431980003953!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0148917971569115!GO:0007010;cytoskeleton organization and biogenesis;0.0149181654012219!GO:0008234;cysteine-type peptidase activity;0.0151891106087085!GO:0008276;protein methyltransferase activity;0.0152992019298488!GO:0005853;eukaryotic translation elongation factor 1 complex;0.0155213652225979!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0155213652225979!GO:0010257;NADH dehydrogenase complex assembly;0.0155213652225979!GO:0033108;mitochondrial respiratory chain complex assembly;0.0155213652225979!GO:0009119;ribonucleoside metabolic process;0.0155658169276928!GO:0046112;nucleobase biosynthetic process;0.0156054174120255!GO:0006509;membrane protein ectodomain proteolysis;0.0156183626638725!GO:0033619;membrane protein proteolysis;0.0156183626638725!GO:0030118;clathrin coat;0.0156577238535578!GO:0050681;androgen receptor binding;0.0156880433530335!GO:0005774;vacuolar membrane;0.016173530223197!GO:0006891;intra-Golgi vesicle-mediated transport;0.0162054168646766!GO:0019783;small conjugating protein-specific protease activity;0.0163334233969311!GO:0016407;acetyltransferase activity;0.0167727371080175!GO:0046822;regulation of nucleocytoplasmic transport;0.0168028432933314!GO:0043189;H4/H2A histone acetyltransferase complex;0.0170242831113264!GO:0000790;nuclear chromatin;0.0175057380475321!GO:0032039;integrator complex;0.0176467663404843!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.0176985226241766!GO:0015036;disulfide oxidoreductase activity;0.0176985226241766!GO:0008097;5S rRNA binding;0.0179475704710651!GO:0004177;aminopeptidase activity;0.0182130680544225!GO:0004843;ubiquitin-specific protease activity;0.0185134188760537!GO:0008538;proteasome activator activity;0.018542729349097!GO:0030041;actin filament polymerization;0.0186735140025008!GO:0016791;phosphoric monoester hydrolase activity;0.0192585886457504!GO:0007041;lysosomal transport;0.0192784340034765!GO:0033673;negative regulation of kinase activity;0.0195630439651152!GO:0006469;negative regulation of protein kinase activity;0.0195630439651152!GO:0031902;late endosome membrane;0.0197498934615997!GO:0003857;3-hydroxyacyl-CoA dehydrogenase activity;0.0199683286194486!GO:0044438;microbody part;0.0199942439466116!GO:0044439;peroxisomal part;0.0199942439466116!GO:0005791;rough endoplasmic reticulum;0.019997347917833!GO:0030508;thiol-disulfide exchange intermediate activity;0.0205637152551435!GO:0005096;GTPase activator activity;0.0207172501416601!GO:0030145;manganese ion binding;0.0208618642618738!GO:0048037;cofactor binding;0.0211448420754646!GO:0016126;sterol biosynthetic process;0.0215696470993347!GO:0006695;cholesterol biosynthetic process;0.0217947788387359!GO:0003887;DNA-directed DNA polymerase activity;0.0218302189524706!GO:0007243;protein kinase cascade;0.0225889713767973!GO:0009081;branched chain family amino acid metabolic process;0.0225972869192845!GO:0043414;biopolymer methylation;0.0226355596695728!GO:0007033;vacuole organization and biogenesis;0.0226355596695728!GO:0006400;tRNA modification;0.0226371386189999!GO:0043631;RNA polyadenylation;0.023055428914249!GO:0051348;negative regulation of transferase activity;0.0230674692158332!GO:0004520;endodeoxyribonuclease activity;0.02307029144114!GO:0004221;ubiquitin thiolesterase activity;0.0241079315748574!GO:0007004;telomere maintenance via telomerase;0.0246105753180945!GO:0006275;regulation of DNA replication;0.0251469456206988!GO:0043241;protein complex disassembly;0.0251551103592917!GO:0004448;isocitrate dehydrogenase activity;0.0256228784690013!GO:0040029;regulation of gene expression, epigenetic;0.026066914437811!GO:0031903;microbody membrane;0.0262282010773162!GO:0005778;peroxisomal membrane;0.0262282010773162!GO:0004523;ribonuclease H activity;0.0264955279893458!GO:0005874;microtubule;0.0270031342178877!GO:0000123;histone acetyltransferase complex;0.0270600600923983!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0270992842040119!GO:0045039;protein import into mitochondrial inner membrane;0.0270992842040119!GO:0022411;cellular component disassembly;0.0270995038581755!GO:0006470;protein amino acid dephosphorylation;0.0278632041963421!GO:0004185;serine carboxypeptidase activity;0.0281181776439642!GO:0009303;rRNA transcription;0.0281879069633501!GO:0035267;NuA4 histone acetyltransferase complex;0.0282618713347724!GO:0007094;mitotic cell cycle spindle assembly checkpoint;0.0283361674891468!GO:0051338;regulation of transferase activity;0.0286807570614342!GO:0006303;double-strand break repair via nonhomologous end joining;0.028690904929338!GO:0030433;ER-associated protein catabolic process;0.029021890840111!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.029021890840111!GO:0006779;porphyrin biosynthetic process;0.0290430697444619!GO:0033014;tetrapyrrole biosynthetic process;0.0290430697444619!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0292547248365689!GO:0044450;microtubule organizing center part;0.029317716619061!GO:0007264;small GTPase mediated signal transduction;0.0298790856270579!GO:0008287;protein serine/threonine phosphatase complex;0.031234038065457!GO:0043549;regulation of kinase activity;0.0315712406592196!GO:0030119;AP-type membrane coat adaptor complex;0.0324073538942626!GO:0005784;translocon complex;0.0324901516475285!GO:0005658;alpha DNA polymerase:primase complex;0.0326978250960194!GO:0046982;protein heterodimerization activity;0.0328380328455041!GO:0004721;phosphoprotein phosphatase activity;0.0329910040223094!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.0329910040223094!GO:0006379;mRNA cleavage;0.0329910040223094!GO:0006672;ceramide metabolic process;0.0329910040223094!GO:0043624;cellular protein complex disassembly;0.0331685110815474!GO:0019318;hexose metabolic process;0.033337485603757!GO:0005996;monosaccharide metabolic process;0.033772555359634!GO:0030100;regulation of endocytosis;0.0337967996986411!GO:0051320;S phase;0.0338266115203575!GO:0009067;aspartate family amino acid biosynthetic process;0.0338985215223741!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.03393294013355!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0345025776050141!GO:0016018;cyclosporin A binding;0.0346423947487908!GO:0044437;vacuolar part;0.0349167592637661!GO:0005777;peroxisome;0.0349167592637661!GO:0042579;microbody;0.0349167592637661!GO:0006740;NADPH regeneration;0.0350167014966831!GO:0006098;pentose-phosphate shunt;0.0350167014966831!GO:0019079;viral genome replication;0.0355190208295375!GO:0000077;DNA damage checkpoint;0.0355190208295375!GO:0030132;clathrin coat of coated pit;0.0356731324188282!GO:0006644;phospholipid metabolic process;0.0363231102544489!GO:0030127;COPII vesicle coat;0.0366882814652104!GO:0012507;ER to Golgi transport vesicle membrane;0.0366882814652104!GO:0005905;coated pit;0.0369977610398546!GO:0031371;ubiquitin conjugating enzyme complex;0.0370376607294752!GO:0006541;glutamine metabolic process;0.0373121771966566!GO:0030133;transport vesicle;0.0374572277396099!GO:0005765;lysosomal membrane;0.0376413979334146!GO:0051452;cellular pH reduction;0.0377447182814878!GO:0051453;regulation of cellular pH;0.0377447182814878!GO:0045851;pH reduction;0.0377447182814878!GO:0045892;negative regulation of transcription, DNA-dependent;0.0378241970672273!GO:0008637;apoptotic mitochondrial changes;0.038207931494485!GO:0006458;'de novo' protein folding;0.0386880447328414!GO:0051084;'de novo' posttranslational protein folding;0.0386880447328414!GO:0004659;prenyltransferase activity;0.0386880447328414!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.03921530201883!GO:0006007;glucose catabolic process;0.0398082631314241!GO:0019206;nucleoside kinase activity;0.0403614041685504!GO:0032603;fractalkine production;0.0403614041685504!GO:0050725;positive regulation of interleukin-1 beta biosynthetic process;0.0403614041685504!GO:0050752;regulation of fractalkine biosynthetic process;0.0403614041685504!GO:0045362;positive regulation of interleukin-1 biosynthetic process;0.0403614041685504!GO:0050754;positive regulation of fractalkine biosynthetic process;0.0403614041685504!GO:0001774;microglial cell activation;0.0403614041685504!GO:0050756;fractalkine metabolic process;0.0403614041685504!GO:0005766;primary lysosome;0.0403614041685504!GO:0050751;fractalkine biosynthetic process;0.0403614041685504!GO:0042222;interleukin-1 biosynthetic process;0.0403614041685504!GO:0050722;regulation of interleukin-1 beta biosynthetic process;0.0403614041685504!GO:0045360;regulation of interleukin-1 biosynthetic process;0.0403614041685504!GO:0042582;azurophil granule;0.0403614041685504!GO:0050720;interleukin-1 beta biosynthetic process;0.0403614041685504!GO:0006607;NLS-bearing substrate import into nucleus;0.0404397728800894!GO:0008156;negative regulation of DNA replication;0.0410842315774975!GO:0005869;dynactin complex;0.041126264074354!GO:0006278;RNA-dependent DNA replication;0.0416425421280022!GO:0001824;blastocyst development;0.0416425421280022!GO:0030134;ER to Golgi transport vesicle;0.0418643716234188!GO:0008537;proteasome activator complex;0.0420572937126782!GO:0030029;actin filament-based process;0.0427877461912069!GO:0004748;ribonucleoside-diphosphate reductase activity;0.0428996417127861!GO:0016728;oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor;0.0428996417127861!GO:0003756;protein disulfide isomerase activity;0.0428996417127861!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0428996417127861!GO:0033367;protein localization in mast cell secretory granule;0.0428996417127861!GO:0033365;protein localization in organelle;0.0428996417127861!GO:0033371;T cell secretory granule organization and biogenesis;0.0428996417127861!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.0428996417127861!GO:0033375;protease localization in T cell secretory granule;0.0428996417127861!GO:0042629;mast cell granule;0.0428996417127861!GO:0033377;maintenance of protein localization in T cell secretory granule;0.0428996417127861!GO:0033364;mast cell secretory granule organization and biogenesis;0.0428996417127861!GO:0033380;granzyme B localization in T cell secretory granule;0.0428996417127861!GO:0033379;maintenance of protease localization in T cell secretory granule;0.0428996417127861!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.0428996417127861!GO:0033368;protease localization in mast cell secretory granule;0.0428996417127861!GO:0033366;protein localization in secretory granule;0.0428996417127861!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.0428996417127861!GO:0033374;protein localization in T cell secretory granule;0.0428996417127861!GO:0006301;postreplication repair;0.0431327146799569!GO:0051297;centrosome organization and biogenesis;0.04317198280652!GO:0031023;microtubule organizing center organization and biogenesis;0.04317198280652!GO:0042809;vitamin D receptor binding;0.0435479466805993!GO:0005092;GDP-dissociation inhibitor activity;0.0437814005903673!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0442286178051371!GO:0008536;Ran GTPase binding;0.0443209540685144!GO:0030522;intracellular receptor-mediated signaling pathway;0.0443253407597817!GO:0033170;DNA-protein loading ATPase activity;0.0446543639830578!GO:0003689;DNA clamp loader activity;0.0446543639830578!GO:0007346;regulation of progression through mitotic cell cycle;0.0447813413895501!GO:0016180;snRNA processing;0.0447931164547344!GO:0016073;snRNA metabolic process;0.0447931164547344!GO:0000086;G2/M transition of mitotic cell cycle;0.0448603476371314!GO:0005666;DNA-directed RNA polymerase III complex;0.0448603476371314!GO:0006467;protein thiol-disulfide exchange;0.0452788775336388!GO:0005744;mitochondrial inner membrane presequence translocase complex;0.046382386404572!GO:0004536;deoxyribonuclease activity;0.0468827985000322!GO:0016646;oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor;0.0469385655931668!GO:0004722;protein serine/threonine phosphatase activity;0.0480094461684114!GO:0030374;ligand-dependent nuclear receptor transcription coactivator activity;0.0480094461684114!GO:0030131;clathrin adaptor complex;0.0484868465113314!GO:0009615;response to virus;0.0488713274383516!GO:0006984;ER-nuclear signaling pathway;0.0490718569123184!GO:0001832;blastocyst growth;0.0494495486523046!GO:0042770;DNA damage response, signal transduction;0.0496186119341307!GO:0003988;acetyl-CoA C-acyltransferase activity;0.04997948461768 | |||
|sample_id=10772 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=blood | |||
|top_motifs=MYB:2.12624025534;E2F1..5:1.75324808807;NFY{A,B,C}:1.33489119083;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.21022376933;bHLH_family:1.13279903785;YY1:1.06653108576;EP300:1.05569388078;ELK1,4_GABP{A,B1}:0.953035414514;BREu{core}:0.945066593907;NRF1:0.936691468057;HBP1_HMGB_SSRP1_UBTF:0.906302498831;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.891038838446;SPIB:0.859059981313;ELF1,2,4:0.857523098169;HIF1A:0.823036870189;ZNF143:0.807474864577;TEF:0.805602661482;SPI1:0.725748955664;PAX8:0.720399714416;PITX1..3:0.710945131674;FOXP1:0.708416259787;DMAP1_NCOR{1,2}_SMARC:0.697543621606;POU5F1:0.654171802531;RUNX1..3:0.62899880336;NANOG{mouse}:0.59009013131;NANOG:0.587599189126;MYOD1:0.553150462497;FOXA2:0.523702872002;VSX1,2:0.51521243888;NKX2-2,8:0.503642181705;NR5A1,2:0.491609171838;ETS1,2:0.425378685853;NKX3-1:0.407238499901;TLX2:0.385698222515;CEBPA,B_DDIT3:0.372622048165;NR6A1:0.367192622365;POU2F1..3:0.354693767216;PBX1:0.34769536293;FOXQ1:0.294835965378;POU3F1..4:0.288452662781;TFDP1:0.286518365425;GATA6:0.281166829808;NFIL3:0.268763932995;CRX:0.256104428371;RFX2..5_RFXANK_RFXAP:0.237839734555;GFI1:0.219484906947;OCT4_SOX2{dimer}:0.202747472133;RBPJ:0.200835448283;CUX2:0.198071036394;HOX{A6,A7,B6,B7}:0.188677185404;FOXD3:0.169794191914;POU1F1:0.168950293125;PAX4:0.164824070734;FOXP3:0.146018900838;PAX5:0.144131290864;HAND1,2:0.14227786506;DBP:0.0983103862964;ZNF238:0.094355380958;TOPORS:0.093388437846;SOX{8,9,10}:0.0864377217255;MTF1:0.0734435365819;ONECUT1,2:0.061832007506;IRF7:0.0597757023907;HOXA9_MEIS1:0.0462277377229;AHR_ARNT_ARNT2:0.0391719458656;NKX2-3_NKX2-5:0.0259282557579;AIRE:0.0166023573604;PDX1:0.0158545787439;HLF:-0.00368067901915;PRRX1,2:-0.00402001736586;ATF5_CREB3:-0.00592425028821;ALX1:-0.00858037462466;IRF1,2:-0.0255094123408;ARID5B:-0.0516649899989;PAX2:-0.0528110943743;REST:-0.0567300090631;CDX1,2,4:-0.0684361361346;AR:-0.0801437482117;BPTF:-0.0813257165345;STAT1,3:-0.0852808793551;EN1,2:-0.0872851547187;IKZF1:-0.0993325194871;LHX3,4:-0.101900806663;HOX{A4,D4}:-0.109315083936;ZNF423:-0.121975672243;HNF1A:-0.146391586424;SNAI1..3:-0.157650242084;PAX6:-0.173935016684;FOXM1:-0.18057553789;ZEB1:-0.184253202001;NKX2-1,4:-0.195591793986;PRDM1:-0.199856303762;HOX{A5,B5}:-0.214047903448;GCM1,2:-0.21743472348;MEF2{A,B,C,D}:-0.225681821917;NKX6-1,2:-0.265557577685;ATF4:-0.266274311597;SREBF1,2:-0.274133640816;FOX{I1,J2}:-0.276667457066;ZBTB16:-0.279170585272;HNF4A_NR2F1,2:-0.281821581435;TBP:-0.285833022075;CREB1:-0.315522223076;PAX3,7:-0.318961046535;IKZF2:-0.32686001174;RFX1:-0.33381017432;KLF4:-0.339540103526;NHLH1,2:-0.369183756759;POU6F1:-0.375598552275;ZFP161:-0.376727130712;NFKB1_REL_RELA:-0.377668241048;MZF1:-0.396248060271;FOX{F1,F2,J1}:-0.428833070205;MYBL2:-0.436745829896;EBF1:-0.448505887404;FOXN1:-0.492744382888;SP1:-0.494073583656;FOS_FOS{B,L1}_JUN{B,D}:-0.495629814988;TGIF1:-0.50151455551;STAT5{A,B}:-0.503516977125;NFE2:-0.510605060022;GATA4:-0.511301438835;RORA:-0.51219162525;HSF1,2:-0.517009157769;FOSL2:-0.517522136314;HES1:-0.517898992445;BACH2:-0.586536035042;UFEwm:-0.597445328423;HIC1:-0.600679103732;LMO2:-0.604367155018;MYFfamily:-0.615287400212;ESRRA:-0.621020668459;ZNF384:-0.637481830736;TFAP2B:-0.64274476932;LEF1_TCF7_TCF7L1,2:-0.65670991321;ALX4:-0.657344607364;SOX17:-0.657703680293;ADNP_IRX_SIX_ZHX:-0.666740043789;PPARG:-0.677918895494;NFIX:-0.70977176692;NKX3-2:-0.71141937957;XBP1:-0.712942742295;SOX5:-0.763281963561;NFE2L2:-0.782637124075;T:-0.783483689804;GTF2A1,2:-0.802434056168;GTF2I:-0.816613769554;ZNF148:-0.822158957924;TP53:-0.851525798993;ATF2:-0.858487429773;ATF6:-0.864179314951;ESR1:-0.877262514368;EVI1:-0.881862114929;GZF1:-0.912408757234;MTE{core}:-0.92086415089;NR3C1:-0.928347183336;RREB1:-0.934575147945;MED-1{core}:-0.956489243866;NFE2L1:-0.976837710407;FOX{D1,D2}:-0.98401615716;FOXL1:-0.986286389159;STAT2,4,6:-0.992187144066;RXRA_VDR{dimer}:-0.994530807788;NR1H4:-0.999540003067;TFAP2{A,C}:-1.00293971155;FOXO1,3,4:-1.00608115397;SRF:-1.01687067241;ZIC1..3:-1.01714050609;TEAD1:-1.03791213683;XCPE1{core}:-1.04341144588;PATZ1:-1.04899156582;MAFB:-1.12335408241;TLX1..3_NFIC{dimer}:-1.12910460208;SOX2:-1.16223171981;HMGA1,2:-1.17114692759;TAL1_TCF{3,4,12}:-1.17284027015;MAZ:-1.18427185311;TFAP4:-1.2226421821;ZBTB6:-1.2306375551;RXR{A,B,G}:-1.24282110954;EGR1..3:-1.24473999066;GFI1B:-1.30083365055;PAX1,9:-1.32553013507;CDC5L:-1.36499331047;SMAD1..7,9:-1.38427945786;TFCP2:-1.42652040703;SPZ1:-1.46998970392;HMX1:-1.49533187031;JUN:-1.51322175239;NFATC1..3:-1.53330777443;TBX4,5:-1.63661162985;GLI1..3:-1.7244774484 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10772-110F7;search_select_hide=table117:FF:10772-110F7 | |||
}} | }} |
Latest revision as of 15:03, 3 June 2020
Name: | myelodysplastic syndrome cell line:SKM-1 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs11934 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11934
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11934
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.231 |
10 | 10 | 0.0701 |
100 | 100 | 0.0925 |
101 | 101 | 0.43 |
102 | 102 | 0.694 |
103 | 103 | 0.695 |
104 | 104 | 0.9 |
105 | 105 | 0.903 |
106 | 106 | 0.00122 |
107 | 107 | 0.0457 |
108 | 108 | 0.43 |
109 | 109 | 0.628 |
11 | 11 | 0.257 |
110 | 110 | 0.881 |
111 | 111 | 0.356 |
112 | 112 | 0.741 |
113 | 113 | 0.215 |
114 | 114 | 0.87 |
115 | 115 | 0.745 |
116 | 116 | 0.722 |
117 | 117 | 0.168 |
118 | 118 | 0.308 |
119 | 119 | 0.186 |
12 | 12 | 0.386 |
120 | 120 | 0.622 |
121 | 121 | 0.559 |
122 | 122 | 0.707 |
123 | 123 | 0.191 |
124 | 124 | 0.79 |
125 | 125 | 0.509 |
126 | 126 | 0.577 |
127 | 127 | 0.15 |
128 | 128 | 0.0635 |
129 | 129 | 0.55 |
13 | 13 | 0.00224 |
130 | 130 | 0.445 |
131 | 131 | 0.0404 |
132 | 132 | 0.704 |
133 | 133 | 0.963 |
134 | 134 | 0.435 |
135 | 135 | 0.139 |
136 | 136 | 0.117 |
137 | 137 | 0.781 |
138 | 138 | 0.504 |
139 | 139 | 0.31 |
14 | 14 | 0.582 |
140 | 140 | 0.305 |
141 | 141 | 0.658 |
142 | 142 | 0.251 |
143 | 143 | 0.0767 |
144 | 144 | 0.541 |
145 | 145 | 0.496 |
146 | 146 | 0.648 |
147 | 147 | 0.0634 |
148 | 148 | 0.251 |
149 | 149 | 0.0303 |
15 | 15 | 0.89 |
150 | 150 | 0.513 |
151 | 151 | 0.182 |
152 | 152 | 0.0109 |
153 | 153 | 0.483 |
154 | 154 | 0.734 |
155 | 155 | 0.231 |
156 | 156 | 0.788 |
157 | 157 | 0.0872 |
158 | 158 | 0.326 |
159 | 159 | 0.818 |
16 | 16 | 0.433 |
160 | 160 | 0.706 |
161 | 161 | 0.819 |
162 | 162 | 0.909 |
163 | 163 | 0.52 |
164 | 164 | 0.0574 |
165 | 165 | 0.866 |
166 | 166 | 0.774 |
167 | 167 | 0.535 |
168 | 168 | 0.0645 |
169 | 169 | 0.281 |
17 | 17 | 0.336 |
18 | 18 | 0.212 |
19 | 19 | 0.567 |
2 | 2 | 0.0778 |
20 | 20 | 0.0575 |
21 | 21 | 0.814 |
22 | 22 | 0.248 |
23 | 23 | 0.00391 |
24 | 24 | 0.0782 |
25 | 25 | 0.474 |
26 | 26 | 0.167 |
27 | 27 | 0.713 |
28 | 28 | 0.848 |
29 | 29 | 0.325 |
3 | 3 | 0.447 |
30 | 30 | 0.0844 |
31 | 31 | 0.0954 |
32 | 32 | 0.133 |
33 | 33 | 0.351 |
34 | 34 | 0.712 |
35 | 35 | 0.732 |
36 | 36 | 0.0409 |
37 | 37 | 0.952 |
38 | 38 | 0.846 |
39 | 39 | 0.362 |
4 | 4 | 0.791 |
40 | 40 | 0.151 |
41 | 41 | 0.413 |
42 | 42 | 0.364 |
43 | 43 | 0.466 |
44 | 44 | 0.705 |
45 | 45 | 0.134 |
46 | 46 | 0.973 |
47 | 47 | 0.179 |
48 | 48 | 0.119 |
49 | 49 | 0.642 |
5 | 5 | 0.361 |
50 | 50 | 0.936 |
51 | 51 | 0.648 |
52 | 52 | 0.0267 |
53 | 53 | 0.846 |
54 | 54 | 0.424 |
55 | 55 | 0.197 |
56 | 56 | 0.573 |
57 | 57 | 0.657 |
58 | 58 | 0.48 |
59 | 59 | 0.711 |
6 | 6 | 0.508 |
60 | 60 | 0.0581 |
61 | 61 | 0.331 |
62 | 62 | 0.874 |
63 | 63 | 0.963 |
64 | 64 | 0.457 |
65 | 65 | 0.279 |
66 | 66 | 0.162 |
67 | 67 | 0.942 |
68 | 68 | 0.296 |
69 | 69 | 0.646 |
7 | 7 | 0.303 |
70 | 70 | 0.0381 |
71 | 71 | 0.207 |
72 | 72 | 0.59 |
73 | 73 | 0.198 |
74 | 74 | 0.173 |
75 | 75 | 0.115 |
76 | 76 | 0.276 |
77 | 77 | 0.216 |
78 | 78 | 0.188 |
79 | 79 | 0.0671 |
8 | 8 | 0.488 |
80 | 80 | 0.26 |
81 | 81 | 0.688 |
82 | 82 | 0.194 |
83 | 83 | 0.674 |
84 | 84 | 0.757 |
85 | 85 | 0.00156 |
86 | 86 | 0.686 |
87 | 87 | 0.187 |
88 | 88 | 0.407 |
89 | 89 | 0.216 |
9 | 9 | 0.999 |
90 | 90 | 0.278 |
91 | 91 | 0.0978 |
92 | 92 | 0.0358 |
93 | 93 | 0.904 |
94 | 94 | 0.915 |
95 | 95 | 0.407 |
96 | 96 | 0.469 |
97 | 97 | 0.383 |
98 | 98 | 0.878 |
99 | 99 | 0.678 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11934
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
DOID:225 syndrome
DOID:74 hematopoietic system disease
EFO:0002091 biological replicate
FF:0000003 cell line sample
FF:0000210 human sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
DOID: Disease
4 (disease)
1287 (cardiovascular system disease)
7 (disease of anatomical entity)
74 (hematopoietic system disease)
225 (syndrome)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
NA