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|ontology_enrichment_disease=DOID:2394!6.32e-09!14;DOID:120!6.36e-09!27;DOID:193!1.47e-08!29
|ontology_enrichment_disease=DOID:2394!6.32e-09!14;DOID:120!6.36e-09!27;DOID:193!1.47e-08!29
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|ontology_enrichment_uberon=UBERON:0003102!1.72e-17!95;UBERON:0000475!1.36e-14!365;UBERON:0005256!3.10e-12!143;UBERON:0000468!6.61e-12!659;UBERON:0000914!8.58e-12!83;UBERON:0002329!8.58e-12!83;UBERON:0003077!8.58e-12!83;UBERON:0003059!8.58e-12!83;UBERON:0007282!8.58e-12!83;UBERON:0009618!8.58e-12!83;UBERON:0007285!8.58e-12!83;UBERON:0002100!1.39e-11!216;UBERON:0000481!2.00e-11!347;UBERON:0000486!7.25e-11!82;UBERON:0003104!3.82e-10!238;UBERON:0009142!3.82e-10!238;UBERON:0002199!5.20e-10!45;UBERON:0002416!5.20e-10!45;UBERON:0002097!6.59e-10!40;UBERON:0000467!9.80e-10!625;UBERON:0000480!1.79e-09!626;UBERON:0004290!3.62e-09!70;UBERON:0004923!5.02e-09!57;UBERON:0005156!3.13e-08!59;UBERON:0000990!3.13e-08!59;UBERON:0001134!3.92e-08!61;UBERON:0002036!3.92e-08!61;UBERON:0003082!3.92e-08!61;UBERON:0002385!4.34e-08!63;UBERON:0001015!4.34e-08!63;UBERON:0000383!4.34e-08!63;UBERON:0000490!4.64e-08!138;UBERON:0003134!1.15e-07!37;UBERON:0000474!1.15e-07!37;UBERON:0003100!1.42e-07!41;UBERON:0004119!2.00e-07!169;UBERON:0000925!2.00e-07!169;UBERON:0006595!2.00e-07!169;UBERON:0000483!2.28e-07!309;UBERON:0000119!3.30e-07!312;UBERON:0000161!5.09e-07!35
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}}
}}

Revision as of 18:29, 8 August 2012


Full id: C2662_Fibroblast_mesenchymal_cervical_leiomyoma_Smooth_Mesothelial_Olfactory



Phase1 CAGE Peaks

Hg19::chr2:151326054..151326068,-p@chr2:151326054..151326068
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Hg19::chr2:151326151..151326158,-p@chr2:151326151..151326158
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Hg19::chr2:151326734..151326756,-p@chr2:151326734..151326756
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Hg19::chr2:151344172..151344187,-p1@RND3


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen
non-terminally differentiated cell8.10e-24180
embryonic cell1.42e-18248
fibroblast9.98e-1675
epithelial cell2.69e-10254
muscle precursor cell5.49e-0957
myoblast5.49e-0957
multi-potent skeletal muscle stem cell5.49e-0957
electrically responsive cell6.07e-0960
electrically active cell6.07e-0960
animal cell1.04e-08679
eukaryotic cell1.04e-08679
mesodermal cell1.89e-08119
skin fibroblast2.65e-0823
smooth muscle cell3.23e-0842
smooth muscle myoblast3.23e-0842
muscle cell6.14e-0854
mesothelial cell9.66e-0719
Uber Anatomy
Ontology termp-valuen
surface structure1.72e-1795
organism subdivision1.36e-14365
trunk mesenchyme3.10e-12143
multi-cellular organism6.61e-12659
somite8.58e-1283
paraxial mesoderm8.58e-1283
presomitic mesoderm8.58e-1283
presumptive segmental plate8.58e-1283
trunk paraxial mesoderm8.58e-1283
presumptive paraxial mesoderm8.58e-1283
trunk1.39e-11216
multi-tissue structure2.00e-11347
multilaminar epithelium7.25e-1182
mesenchyme3.82e-10238
entire embryonic mesenchyme3.82e-10238
integument5.20e-1045
integumental system5.20e-1045
skin of body6.59e-1040
anatomical system9.80e-10625
anatomical group1.79e-09626
dermomyotome3.62e-0970
organ component layer5.02e-0957
reproductive structure3.13e-0859
reproductive system3.13e-0859
skeletal muscle tissue3.92e-0861
striated muscle tissue3.92e-0861
myotome3.92e-0861
muscle tissue4.34e-0863
musculature4.34e-0863
musculature of body4.34e-0863
unilaminar epithelium4.64e-08138
female reproductive organ1.15e-0737
female reproductive system1.15e-0737
female organism1.42e-0741
endoderm-derived structure2.00e-07169
endoderm2.00e-07169
presumptive endoderm2.00e-07169
epithelium2.28e-07309
cell layer3.30e-07312
orifice5.09e-0735
Disease
Ontology termp-valuen
ovarian cancer6.32e-0914
female reproductive organ cancer6.36e-0927
reproductive organ cancer1.47e-0829


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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