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|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0000914!3.99e-17!83;UBERON:0002329!3.99e-17!83;UBERON:0003077!3.99e-17!83;UBERON:0003059!3.99e-17!83;UBERON:0007282!3.99e-17!83;UBERON:0009618!3.99e-17!83;UBERON:0007285!3.99e-17!83;UBERON:0004290!4.28e-16!70;UBERON:0000486!5.61e-13!82;UBERON:0001134!1.54e-11!61;UBERON:0002036!1.54e-11!61;UBERON:0003082!1.54e-11!61;UBERON:0002097!2.09e-11!40;UBERON:0002385!1.01e-10!63;UBERON:0001015!1.01e-10!63;UBERON:0000383!1.01e-10!63;UBERON:0002199!1.41e-10!45;UBERON:0002416!1.41e-10!45;UBERON:0002204!4.09e-10!167;UBERON:0005256!2.74e-09!143;UBERON:0000475!2.99e-08!365;UBERON:0002384!3.47e-08!375;UBERON:0003102!4.62e-07!95;UBERON:0002067!5.55e-07!9;UBERON:0004016!5.55e-07!9;UBERON:0010083!5.55e-07!9
|ontology_enrichment_uberon=UBERON:0000914!3.99e-17!83;UBERON:0002329!3.99e-17!83;UBERON:0003077!3.99e-17!83;UBERON:0003059!3.99e-17!83;UBERON:0007282!3.99e-17!83;UBERON:0009618!3.99e-17!83;UBERON:0007285!3.99e-17!83;UBERON:0004290!4.28e-16!70;UBERON:0000486!5.61e-13!82;UBERON:0001134!1.54e-11!61;UBERON:0002036!1.54e-11!61;UBERON:0003082!1.54e-11!61;UBERON:0002097!2.09e-11!40;UBERON:0002385!1.01e-10!63;UBERON:0001015!1.01e-10!63;UBERON:0000383!1.01e-10!63;UBERON:0002199!1.41e-10!45;UBERON:0002416!1.41e-10!45;UBERON:0002204!4.09e-10!167;UBERON:0005256!2.74e-09!143;UBERON:0000475!2.99e-08!365;UBERON:0002384!3.47e-08!375;UBERON:0003102!4.62e-07!95;UBERON:0002067!5.55e-07!9;UBERON:0004016!5.55e-07!9;UBERON:0010083!5.55e-07!9
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}}
}}

Revision as of 19:14, 8 August 2012


Full id: C3521_mesenchymal_Hair_Preadipocyte_Fibroblast_Myoblast_granulosa_Osteoblast



Phase1 CAGE Peaks

Hg19::chr15:80806571..80806585,+p@chr15:80806571..80806585
+
Hg19::chr15:80806653..80806664,+p@chr15:80806653..80806664
+
Hg19::chr15:80806674..80806703,+p@chr15:80806674..80806703
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
non-terminally differentiated cell7.93e-40180
fibroblast1.92e-2975
multi fate stem cell1.37e-17430
somatic stem cell1.53e-16436
stem cell3.31e-15444
skin fibroblast2.23e-1423
muscle precursor cell1.23e-1257
myoblast1.23e-1257
multi-potent skeletal muscle stem cell1.23e-1257
muscle cell6.57e-1154
motile cell1.61e-09390
electrically responsive cell3.39e-0960
electrically active cell3.39e-0960
contractile cell6.32e-0959
somatic cell9.01e-09591
smooth muscle cell9.19e-0942
smooth muscle myoblast9.19e-0942
mesenchymal cell2.00e-08358
connective tissue cell7.13e-08365
mesodermal cell1.87e-07119
preadipocyte4.09e-0712
Uber Anatomy
Ontology termp-valuen
somite3.99e-1783
paraxial mesoderm3.99e-1783
presomitic mesoderm3.99e-1783
presumptive segmental plate3.99e-1783
trunk paraxial mesoderm3.99e-1783
presumptive paraxial mesoderm3.99e-1783
dermomyotome4.28e-1670
multilaminar epithelium5.61e-1382
skeletal muscle tissue1.54e-1161
striated muscle tissue1.54e-1161
myotome1.54e-1161
skin of body2.09e-1140
muscle tissue1.01e-1063
musculature1.01e-1063
musculature of body1.01e-1063
integument1.41e-1045
integumental system1.41e-1045
musculoskeletal system4.09e-10167
trunk mesenchyme2.74e-09143
organism subdivision2.99e-08365
connective tissue3.47e-08375
surface structure4.62e-0795
dermis5.55e-079
dermatome5.55e-079
future dermis5.55e-079


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.