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{{Coexpression_clusters
{{Coexpression_clusters
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|full_id=C1985_gastric_signet_lymphangiectasia_Prostate_smallcell_Intestinal_teratocarcinoma
|full_id=C1985_gastric_signet_lymphangiectasia_Prostate_smallcell_Intestinal_teratocarcinoma
|id=C1985
|id=C1985

Revision as of 14:37, 12 September 2012


Full id: C1985_gastric_signet_lymphangiectasia_Prostate_smallcell_Intestinal_teratocarcinoma



Phase1 CAGE Peaks

Hg19::chr7:12971296..12971310,+p@chr7:12971296..12971310
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Hg19::chr7:12997533..12997536,+p@chr7:12997533..12997536
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Hg19::chr7:13447097..13447101,+p@chr7:13447097..13447101
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Hg19::chr7:13524410..13524415,+p@chr7:13524410..13524415
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Hg19::chr7:13545393..13545395,+p@chr7:13545393..13545395
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neocortex9.88e-1520
regional part of cerebral cortex1.97e-1422
cerebral hemisphere1.01e-1332
telencephalon1.76e-1234
cerebral cortex5.20e-1225
pallium5.20e-1225
regional part of telencephalon5.95e-1233
adult organism1.50e-11115
gray matter2.14e-1134
brain grey matter2.14e-1134
regional part of forebrain3.89e-0941
forebrain3.89e-0941
future forebrain3.89e-0941
anterior neural tube9.34e-0942
neural plate1.35e-0886
presumptive neural plate1.35e-0886
neurectoderm2.10e-0890
central nervous system2.96e-0782
neural tube3.33e-0757
neural rod3.33e-0757
future spinal cord3.33e-0757
neural keel3.33e-0757
regional part of nervous system4.34e-0794
nervous system4.34e-0794
pre-chordal neural plate5.96e-0761


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.