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Coexpression cluster:C1227

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Full id: C1227_Osteoblast_Smooth_tenocyte_Fibroblast_Chondrocyte_Aortic_Hair



Phase1 CAGE Peaks

Hg19::chr17:39969465..39969488,+p3@FKBP10
Hg19::chr17:39974337..39974365,+p@chr17:39974337..39974365
+
Hg19::chr17:39974415..39974450,+p@chr17:39974415..39974450
+
Hg19::chr17:39975455..39975487,+p5@FKBP10
Hg19::chr17:39975580..39975609,+p4@FKBP10
Hg19::chr17:39975867..39975886,+p12@FKBP10
Hg19::chr1:12012673..12012703,+p@chr1:12012673..12012703
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
epithelial vesicle2.47e-1978
dense mesenchyme tissue9.68e-1873
somite2.20e-1771
presomitic mesoderm2.20e-1771
presumptive segmental plate2.20e-1771
dermomyotome2.20e-1771
trunk paraxial mesoderm2.20e-1771
paraxial mesoderm3.61e-1772
presumptive paraxial mesoderm3.61e-1772
mesenchyme7.17e-17160
entire embryonic mesenchyme7.17e-17160
splanchnic layer of lateral plate mesoderm8.42e-1683
vasculature2.28e-1578
vascular system2.28e-1578
trunk mesenchyme2.67e-15122
multilaminar epithelium2.69e-1583
skeletal muscle tissue7.28e-1562
striated muscle tissue7.28e-1562
myotome7.28e-1562
unilaminar epithelium1.22e-14148
muscle tissue2.35e-1464
musculature2.35e-1464
musculature of body2.35e-1464
artery2.81e-1442
arterial blood vessel2.81e-1442
arterial system2.81e-1442
epithelial tube4.67e-14117
epithelial tube open at both ends4.71e-1459
blood vessel4.71e-1459
blood vasculature4.71e-1459
vascular cord4.71e-1459
trunk1.90e-13199
vessel3.95e-1368
organism subdivision7.08e-13264
systemic artery1.56e-1133
systemic arterial system1.56e-1133
cardiovascular system6.23e-11109
circulatory system3.32e-10112
multi-cellular organism1.99e-09656
cell layer9.16e-09309
integument1.35e-0846
integumental system1.35e-0846
epithelium1.64e-08306
multi-tissue structure3.88e-08342
surface structure5.51e-0899
mesoderm4.65e-07315
mesoderm-derived structure4.65e-07315
presumptive mesoderm4.65e-07315
anatomical system6.80e-07624
skin of body7.79e-0741
anatomical group8.39e-07625


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.