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Coexpression cluster:C1487

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Full id: C1487_Renal_lung_kidney_ductus_seminal_Skeletal_Urothelial



Phase1 CAGE Peaks

Hg19::chr21:39628703..39628733,+p10@KCNJ15
Hg19::chr21:39628748..39628769,+p15@KCNJ15
Hg19::chr21:39628780..39628801,+p16@KCNJ15
Hg19::chr21:39628852..39628867,+p12@KCNJ15
Hg19::chr21:39628885..39628905,+p13@KCNJ15
Hg19::chr21:39628906..39628919,+p7@KCNJ15


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
renal system6.07e-1545
urinary system structure2.18e-1444
intermediate mesoderm3.70e-1137
cavitated compound organ7.14e-1132
mesonephros1.61e-1018
pronephros1.61e-1018
nephrogenic cord1.61e-1018
pronephric mesoderm1.61e-1018
rostral part of nephrogenic cord1.61e-1018
presumptive pronephric mesoderm1.61e-1018
intraembryonic coelom1.75e-1021
urogenital ridge2.32e-1020
kidney5.10e-1027
kidney mesenchyme5.10e-1027
kidney rudiment5.10e-1027
kidney field5.10e-1027
excretory tube1.54e-0917
mesonephric epithelium1.54e-0917
mesonephric tubule1.54e-0917
nephric duct1.54e-0917
kidney epithelium1.54e-0917
renal duct1.54e-0917
mesonephric duct1.54e-0917
pronephric duct1.54e-0917
renal tubule3.90e-0912
nephron tubule3.90e-0912
nephron tubule epithelium3.90e-0912
nephron epithelium1.18e-0816
nephron1.18e-0816
uriniferous tubule1.18e-0816
metanephric mesenchyme1.18e-0816
nephrogenic mesenchyme1.18e-0816
duct3.59e-0826
mesoderm5.77e-07448
mesoderm-derived structure5.77e-07448
presumptive mesoderm5.77e-07448


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.