MCL coexpression mm9:510

Phase1 CAGE Peaks

	Short description
Mm9::chr10:24431715..24431724,-	p5@Enpp1
Mm9::chr10:24431739..24431755,-	p3@Enpp1
Mm9::chr12:104932242..104932259,-	p@chr12:104932242..104932259 -
Mm9::chr12:104932867..104932883,-	p2@Serpina1f
Mm9::chr12:104932884..104932890,-	p7@Serpina1f
Mm9::chr12:104932896..104932913,-	p3@Serpina1f
Mm9::chr12:104932923..104932928,-	p6@Serpina1f
Mm9::chr14:23599754..23599757,-	p@chr14:23599754..23599757 -
Mm9::chr14:30665533..30665556,-	p@chr14:30665533..30665556 -
Mm9::chr2:151931776..151931792,-	p@chr2:151931776..151931792 -
Mm9::chr2:164047341..164047413,-	p1@Wfdc15b
Mm9::chr7:93924449..93924458,-	p6@Folh1
Mm9::chr8:26880055..26880065,-	p@chr8:26880055..26880065 -
Mm9::chrX:136343134..136343167,+	p@chrX:136343134..136343167 +

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0008464	gamma-glutamyl hydrolase activity	0.0175270426943596
GO:0004528	phosphodiesterase I activity	0.0175270426943596
GO:0043275	glutamate carboxypeptidase II activity	0.0175270426943596
GO:0008242	omega peptidase activity	0.0175270426943596
GO:0004237	membrane dipeptidase activity	0.0175270426943596
GO:0016338	calcium-independent cell-cell adhesion	0.0219034020359721
GO:0004551	nucleotide diphosphatase activity	0.0219034020359721
GO:0030279	negative regulation of ossification	0.024637277031428
GO:0006760	folic acid and derivative metabolic process	0.0267620247908273
GO:0046851	negative regulation of bone remodeling	0.0278610226768299
GO:0016805	dipeptidase activity	0.0278610226768299
GO:0005886	plasma membrane	0.0341921914068935
GO:0030278	regulation of ossification	0.0403805849468389
GO:0051241	negative regulation of multicellular organismal process	0.0409913083966342
GO:0046850	regulation of bone remodeling	0.0409913083966342
GO:0004181	metallocarboxypeptidase activity	0.0409913083966342

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
kidney	7.58e-31	14
kidney mesenchyme	7.58e-31	14
upper urinary tract	7.58e-31	14
kidney rudiment	7.58e-31	14
kidney field	7.58e-31	14
urinary system structure	7.12e-24	18
renal system	1.38e-22	19
cavitated compound organ	2.21e-20	21
epididymis	2.17e-10	3
excretory tube	2.17e-10	3
mesonephric epithelium	2.17e-10	3
mesonephric tubule	2.17e-10	3
nephric duct	2.17e-10	3
kidney epithelium	2.17e-10	3
renal duct	2.17e-10	3
mesonephric duct	2.17e-10	3
pronephric duct	2.17e-10	3
compound organ	1.31e-09	43
abdomen element	2.44e-08	49
abdominal segment element	2.44e-08	49
abdominal segment of trunk	2.44e-08	49
abdomen	2.44e-08	49
mesonephros	5.22e-08	4
duct of male reproductive system	5.22e-08	4
male genital duct	5.22e-08	4
pronephros	5.22e-08	4
internal male genitalia	5.22e-08	4
nephrogenic cord	5.22e-08	4
urogenital ridge	5.22e-08	4
pronephric mesoderm	5.22e-08	4
rostral part of nephrogenic cord	5.22e-08	4
presumptive pronephric mesoderm	5.22e-08	4

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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