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MCL coexpression mm9:2281

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Phase1 CAGE Peaks

 Short description
Mm9::chr1:132774997..132775019,+p4@Faim3
Mm9::chr2:13715640..13715652,-p3@St8sia6
Mm9::chr2:13715659..13715668,-p6@St8sia6
Mm9::chrX:10294577..10294582,-p2@ENSMUST00000101687


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0009247glycolipid biosynthetic process0.0250935186815063
GO:0006493protein amino acid O-linked glycosylation0.0250935186815063
GO:0006664glycolipid metabolic process0.0250935186815063
GO:0008373sialyltransferase activity0.0250935186815063
GO:0030173integral to Golgi membrane0.0250935186815063
GO:0031228intrinsic to Golgi membrane0.0250935186815063
GO:0031301integral to organelle membrane0.0360762254170714
GO:0031300intrinsic to organelle membrane0.0360762254170714
GO:0000139Golgi membrane0.0360762254170714
GO:0046467membrane lipid biosynthetic process0.0360762254170714
GO:0006486protein amino acid glycosylation0.0360762254170714
GO:0043413biopolymer glycosylation0.0360762254170714
GO:0016051carbohydrate biosynthetic process0.0360762254170714
GO:0009101glycoprotein biosynthetic process0.0360762254170714
GO:0009100glycoprotein metabolic process0.0392679008747741
GO:0044431Golgi apparatus part0.0495394347287502



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
thymocyte1.27e-096
double negative thymocyte1.27e-096
naive T cell1.27e-096
double-positive, alpha-beta thymocyte1.27e-096
CD4-positive, alpha-beta thymocyte1.27e-096
naive thymus-derived CD4-positive, alpha-beta T cell1.27e-096
DN4 thymocyte1.27e-096
DN1 thymic pro-T cell1.27e-096
DN2 thymocyte1.27e-096
DN3 thymocyte1.27e-096
immature single positive thymocyte1.27e-096
early T lineage precursor1.27e-096
mature CD4 single-positive thymocyte1.27e-096
resting double-positive thymocyte1.27e-096
double-positive blast1.27e-096
CD69-positive double-positive thymocyte1.27e-096
CD69-positive, CD4-positive single-positive thymocyte1.27e-096
CD4-positive, CD8-intermediate double-positive thymocyte1.27e-096
CD24-positive, CD4 single-positive thymocyte1.27e-096
CD4-positive, alpha-beta T cell1.32e-098
mature alpha-beta T cell2.17e-089
alpha-beta T cell2.17e-089
immature T cell2.17e-089
mature T cell2.17e-089
immature alpha-beta T cell2.17e-089
lymphoid lineage restricted progenitor cell7.39e-0812
lymphocyte3.99e-0713
common lymphoid progenitor3.99e-0713


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.331308
MA0004.11.64673
MA0006.10.497533
MA0007.10.672186
MA0009.11.15569
MA0014.10.276754
MA0017.10.528196
MA0019.12.21448
MA0024.11.11019
MA0025.11.39562
MA0027.12.81824
MA0028.10.509589
MA0029.11.08753
MA0030.11.09438
MA0031.11.05719
MA0038.10.846479
MA0040.11.16866
MA0041.10.604221
MA0042.10.589368
MA0043.11.25564
MA0046.11.1929
MA0048.10.735223
MA0050.10.731539
MA0051.10.856094
MA0052.11.17701
MA0055.10.125758
MA0056.10
MA0057.10.251896
MA0058.11.4226
MA0059.11.45189
MA0060.10.403071
MA0061.10.438628
MA0063.10
MA0066.10.834648
MA0067.11.50873
MA0068.10.256913
MA0069.11.17737
MA0070.11.16732
MA0071.10.73062
MA0072.11.15853
MA0073.10.00221226
MA0074.10.795862
MA0076.10.550092
MA0077.11.13603
MA0078.10.891476
MA0081.10.621611
MA0083.11.25482
MA0084.11.84013
MA0087.11.21037
MA0088.10.582815
MA0089.10
MA0090.10.650768
MA0091.10.703314
MA0092.10.651119
MA0093.12.22418
MA0095.10
MA0098.10
MA0100.10.783305
MA0101.10.605676
MA0103.10.540576
MA0105.11.52164
MA0106.10.899777
MA0107.11.3208
MA0108.20.989014
MA0109.10
MA0111.10.666525
MA0113.10.869608
MA0114.10.43587
MA0115.11.25852
MA0116.10.497293
MA0117.11.22527
MA0119.11.47447
MA0122.11.24573
MA0124.11.45461
MA0125.11.37907
MA0130.10
MA0131.10.960068
MA0132.10
MA0133.10
MA0135.11.29308
MA0136.10.817395
MA0139.10.365453
MA0140.10.78318
MA0141.11.38335
MA0142.11.04199
MA0143.10.887119
MA0144.11.95888
MA0145.10.608454
MA0146.10.313734
MA0147.11.15069
MA0148.10.706718
MA0149.10.611881
MA0062.20.319836
MA0035.20.788288
MA0039.20.45096
MA0138.20.951653
MA0002.20.368961
MA0137.20.559766
MA0104.21.0034
MA0047.20.845655
MA0112.20.211985
MA0065.20.212467
MA0150.10.67206
MA0151.10
MA0152.10.84577
MA0153.11.31015
MA0154.10.263609
MA0155.10.230016
MA0156.10.549102
MA0157.11.0083
MA0158.10
MA0159.10.465802
MA0160.10.71003
MA0161.10
MA0162.11.16288
MA0163.10.327769
MA0164.10.817786
MA0080.20.534538
MA0018.20.828253
MA0099.20.944966
MA0079.20.0553806
MA0102.21.8929
MA0258.11.07695
MA0259.11.96515
MA0442.10