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Coexpression cluster:C571

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Full id: C571_Bronchial_Prostate_Small_Tracheal_Mallassezderived_Urothelial_Gingival



Phase1 CAGE Peaks

Hg19::chr17:73724438..73724471,+p@chr17:73724438..73724471
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Hg19::chr17:73725353..73725387,+p@chr17:73725353..73725387
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Hg19::chr17:73726320..73726332,+p@chr17:73726320..73726332
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Hg19::chr1:183177006..183177041,+p@chr1:183177006..183177041
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Hg19::chr1:183177076..183177103,+p@chr1:183177076..183177103
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Hg19::chr1:209790813..209790826,-p@chr1:209790813..209790826
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Hg19::chr1:209796354..209796366,-p@chr1:209796354..209796366
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Hg19::chr1:209800857..209800874,-p@chr1:209800857..209800874
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Hg19::chr1:209801414..209801425,-p@chr1:209801414..209801425
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Hg19::chr1:209806051..209806064,-p@chr1:209806051..209806064
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Hg19::chr1:209806472..209806488,-p@chr1:209806472..209806488
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Hg19::chr1:209807970..209807983,-p@chr1:209807970..209807983
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Hg19::chr1:209823365..209823389,-p@chr1:209823365..209823389
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Hg19::chr1:209823405..209823427,-p@chr1:209823405..209823427
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Hg19::chr1:209823455..209823467,-p@chr1:209823455..209823467
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Hg19::chr20:388836..388841,+p8@RBCK1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Uber Anatomy
Ontology termp-valuen
organ1.63e-17511
endoderm-derived structure8.72e-16169
endoderm8.72e-16169
presumptive endoderm8.72e-16169
embryonic structure1.93e-11605
developing anatomical structure1.93e-11605
multi-cellular organism2.42e-11659
germ layer3.01e-11604
embryonic tissue3.01e-11604
presumptive structure3.01e-11604
epiblast (generic)3.01e-11604
anatomical system3.35e-11625
anatomical group5.22e-11626
digestive system6.91e-11155
digestive tract6.91e-11155
primitive gut6.91e-11155
embryo1.01e-10612
respiratory system6.65e-1072
mixed endoderm/mesoderm-derived structure1.36e-09130
subdivision of digestive tract4.74e-09129
endodermal part of digestive tract4.74e-09129
organ part8.20e-09219
anatomical space5.65e-08104
respiratory tract1.50e-0753
extraembryonic membrane2.13e-0714
membranous layer2.13e-0714
foregut3.62e-0798
respiratory primordium6.80e-0738
endoderm of foregut6.80e-0738
Disease
Ontology termp-valuen
carcinoma1.34e-13106
cell type cancer2.00e-10143
adenocarcinoma1.08e-0825
squamous cell carcinoma5.67e-0714


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.