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Coexpression cluster:C316

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Full id: C316_hepatic_Hair_Fibroblast_spindle_Preadipocyte_tenocyte_Ewing



Phase1 CAGE Peaks

Hg19::chr15:33010194..33010211,+p1@GREM1
Hg19::chr15:33010431..33010449,+p@chr15:33010431..33010449
+
Hg19::chr15:33022885..33022907,+p12@GREM1
Hg19::chr15:33022910..33022924,+p13@GREM1
Hg19::chr15:33022957..33022966,-p14@CU686887
Hg19::chr15:33022972..33022997,+p3@GREM1
Hg19::chr15:33023020..33023043,-p2@CU686887
Hg19::chr15:33023069..33023091,+p5@GREM1
Hg19::chr15:33023095..33023177,+p2@GREM1
Hg19::chr15:33023166..33023177,-p12@CU686887
Hg19::chr15:33023180..33023193,+p15@GREM1
Hg19::chr15:33023199..33023239,+p7@GREM1
Hg19::chr15:33023250..33023262,+p19@GREM1
Hg19::chr15:33023284..33023311,-p4@CU686887
Hg19::chr15:33023286..33023299,+p4@GREM1
Hg19::chr15:33023302..33023311,+p27@GREM1
Hg19::chr15:33023323..33023333,+p20@GREM1
Hg19::chr15:33023369..33023426,-p1@CU686887
Hg19::chr15:33023489..33023500,-p8@CU686887
Hg19::chr15:33023541..33023550,-p10@CU686887
Hg19::chr15:33023745..33023757,+p11@GREM1
Hg19::chr15:33023840..33023851,+p14@GREM1
Hg19::chr15:33023873..33023883,+p22@GREM1
Hg19::chr15:33024106..33024122,+p9@GREM1
Hg19::chr15:33024150..33024170,-p@chr15:33024150..33024170
-
Hg19::chr15:33024167..33024179,+p18@GREM1
Hg19::chr15:33024232..33024264,-p@chr15:33024232..33024264
-
Hg19::chr15:33024456..33024470,+p6@GREM1
Hg19::chr15:33024736..33024758,+p10@GREM1
Hg19::chr15:33024771..33024780,+p24@GREM1
Hg19::chr15:33024966..33024984,+p21@GREM1
Hg19::chr15:33024989..33024999,+p17@GREM1
Hg19::chr15:33025032..33025060,+p8@GREM1
Hg19::chr15:33025271..33025279,+p@chr15:33025271..33025279
+
Hg19::chr15:33025543..33025554,+p@chr15:33025543..33025554
+
Hg19::chr15:33025787..33025805,+p@chr15:33025787..33025805
+
Hg19::chr15:33026325..33026338,+p@chr15:33026325..33026338
+
Hg19::chr17:30745..30746,-p@chr17:30745..30746
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
somite3.38e-2583
paraxial mesoderm3.38e-2583
presomitic mesoderm3.38e-2583
presumptive segmental plate3.38e-2583
trunk paraxial mesoderm3.38e-2583
presumptive paraxial mesoderm3.38e-2583
dermomyotome1.33e-2170
trunk mesenchyme5.27e-21143
organism subdivision5.84e-20365
multilaminar epithelium3.55e-1882
muscle tissue8.05e-1863
musculature8.05e-1863
musculature of body8.05e-1863
skeletal muscle tissue8.95e-1861
striated muscle tissue8.95e-1861
myotome8.95e-1861
multi-tissue structure2.84e-13347
multi-cellular organism4.36e-13659
trunk1.76e-12216
cell layer1.59e-10312
epithelium4.12e-10309
anatomical system4.78e-10625
integument7.53e-1045
integumental system7.53e-1045
anatomical group7.81e-10626
surface structure6.67e-0995
skin of body1.89e-0840
artery6.82e-0842
arterial blood vessel6.82e-0842
arterial system6.82e-0842
systemic artery8.38e-0833
systemic arterial system8.38e-0833
smooth muscle tissue1.84e-0715
anatomical cluster2.21e-07286
unilaminar epithelium5.68e-07138
splanchnic layer of lateral plate mesoderm6.22e-0784
embryo7.43e-07612
mesenchyme7.94e-07238
entire embryonic mesenchyme7.94e-07238


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.