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MCL coexpression mm9:1063

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Phase1 CAGE Peaks

  Short description
Mm9::chr11:120442510..120442551,- p2@Arhgdia
Mm9::chr2:119000878..119000908,- p@chr2:119000878..119000908
-
Mm9::chr2:32485293..32485323,+ p8@Ak1
Mm9::chr3:90417204..90417214,+ p@chr3:90417204..90417214
+
Mm9::chr5:114828952..114828966,+ p@chr5:114828952..114828966
+
Mm9::chr5:136364908..136364912,+ p@chr5:136364908..136364912
+
Mm9::chr7:52721748..52721798,- p3@Bax


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


GO IDGO nameFDR corrected p-value
GO:0030850prostate gland development0.0298225414540824
GO:0005094Rho GDP-dissociation inhibitor activity0.0298225414540824
GO:0005092GDP-dissociation inhibitor activity0.0298225414540824
GO:0050680negative regulation of epithelial cell proliferation0.0298225414540824
GO:0004017adenylate kinase activity0.0318072249064509
GO:0007431salivary gland development0.0372597960816936
GO:0035272exocrine system development0.0372597960816936
GO:0019201nucleotide kinase activity0.0372597960816936
GO:0001772immunological synapse0.044147658872444
GO:0050678regulation of epithelial cell proliferation0.0476690193797403



Relative expression of the co-expression cluster over median
Analyst:





Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset

cell_data
uberon_data


Cell Type
Ontology termp-valuen
migratory neural crest cell3.39e-2110
neuron associated cell3.39e-2110
glial cell (sensu Vertebrata)3.39e-2110
neuron associated cell (sensu Vertebrata)3.39e-2110
glial cell3.39e-2110
glioblast3.39e-2110
glioblast (sensu Vertebrata)3.39e-2110
oligodendrocyte precursor cell1.14e-178
oligodendrocyte6.66e-146
macroglial cell6.66e-146
astrocyte6.66e-146
muscle precursor cell6.72e-136
contractile cell6.72e-136
muscle cell6.72e-136
myoblast6.72e-136
mesodermal cell6.24e-117
non-terminally differentiated cell4.67e-0949
multi-potent skeletal muscle stem cell2.63e-089
embryonic cell1.10e-0770
cardiocyte1.49e-073
striated muscle cell1.49e-073
cardiac muscle cell1.49e-073
cardiac muscle myoblast1.49e-073
smooth muscle cell5.93e-073
vascular associated smooth muscle cell5.93e-073
aortic smooth muscle cell5.93e-073
smooth muscle myoblast5.93e-073
duct epithelial cell8.97e-073
epithelial cell of tracheobronchial tree8.97e-073
branched duct epithelial cell8.97e-073
epithelial cell of lower respiratory tract8.97e-073
respiratory epithelial cell8.97e-073
tracheal epithelial cell8.97e-073
tracheoblast8.97e-073


TFBS overrepresentationSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.11.4232
MA0004.11.20906
MA0006.10.311391
MA0007.10.465969
MA0009.10.92425
MA0014.11.84673
MA0017.10.337808
MA0019.10.740036
MA0024.10.880057
MA0025.11.15921
MA0027.12.57545
MA0028.10.321735
MA0029.10.858105
MA0030.10.864739
MA0031.10.828781
MA0038.10.62758
MA0040.10.936879
MA0041.10.404721
MA0042.10.391504
MA0043.11.02178
MA0046.10.960497
MA0048.10.128106
MA0050.10.520357
MA0051.10.636645
MA0052.10.945011
MA0055.10.157978
MA0056.10
MA0057.10.117936
MA0058.10.384683
MA0059.10.397033
MA0060.10.232592
MA0061.10.724575
MA0063.10
MA0066.10.616444
MA0067.11.27078
MA0068.11.25994
MA0069.10.945354
MA0070.10.93557
MA0071.10.519509
MA0072.10.927016
MA0073.10.351935
MA0074.11.41926
MA0076.10.356883
MA0077.10.905143
MA0078.10.670113
MA0081.10.420276
MA0083.11.02098
MA0084.11.59945
MA0087.10.977537
MA0088.11.00582
MA0089.10
MA0090.11.1347
MA0091.10.494398
MA0092.10.446857
MA0093.10.879104
MA0095.10
MA0098.10
MA0100.10.568369
MA0101.10.406019
MA0103.10.348572
MA0105.12.16336
MA0106.13.97307
MA0107.10.342432
MA0108.20.763162
MA0109.10
MA0111.10.460823
MA0113.10.649407
MA0114.10.259463
MA0115.11.0246
MA0116.10.836994
MA0117.10.992087
MA0119.10.40661
MA0122.11.01209
MA0124.11.21735
MA0125.11.14291
MA0130.10
MA0131.10.735438
MA0132.10
MA0133.10
MA0135.11.05845
MA0136.10.600242
MA0139.10.585936
MA0140.10.568252
MA0141.10.368264
MA0142.10.814115
MA0143.10.665982
MA0144.10.262477
MA0145.10.0910975
MA0146.12.04073
MA0147.10.753844
MA0148.10.49752
MA0149.19.84709
MA0062.20.500692
MA0035.20.573016
MA0039.21.72008
MA0138.20.727395
MA0002.20.205289
MA0137.20.365364
MA0104.20.624968
MA0047.20.626803
MA0112.22.13872
MA0065.20.0914071
MA0150.10.465855
MA0151.10
MA0152.10.626912
MA0153.11.07519
MA0154.10.792589
MA0155.11.67164
MA0156.10.936991
MA0157.10.781683
MA0158.10
MA0159.10.776527
MA0160.10.50056
MA0161.10
MA0162.10.0312493
MA0163.11.20194
MA0164.10.600609
MA0080.20.908823
MA0018.20.610433
MA0099.20.721008
MA0079.20.86982
MA0102.21.65195
MA0258.10.688848
MA0259.10.729797
MA0442.10