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{{f5samples
{{f5samples
|F5samples=
|DRA_sample_Accession=CAGE@SAMD00005140
|ancestors_in_anatomy_facet=UBERON:0000061,UBERON:0000465,UBERON:0000479,UBERON:0001062,UBERON:0002384
|accession_numbers=CAGE;DRX007909;DRR008781;DRZ000206;DRZ001591;DRZ011556;DRZ012941
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000004,CL:0000012,CL:0000034,CL:0000037,CL:0000048,CL:0000051,CL:0000063,CL:0000134,CL:0000144,CL:0000219,CL:0000255,CL:0000542,CL:0000548,CL:0000566,CL:0000723,CL:0000738,CL:0000826,CL:0000837,CL:0000838,CL:0000945,CL:0000988,CL:0002031,CL:0002032,CL:0002087,CL:0002320,CL:0002371
|ancestors_in_anatomy_facet=
|ancestors_in_disease_facet=DOID:0050686,DOID:0060058,DOID:0060083,DOID:1287,DOID:14566,DOID:162,DOID:2355,DOID:2531,DOID:4,DOID:7,DOID:74
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0002371,CL:0000542,CL:0000219,CL:0000945,CL:0000738,CL:0002087,CL:0002242,CL:0000255
|ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:2531,DOID:0060058,DOID:14566,DOID:0060083,DOID:1287,DOID:7,DOID:74,DOID:2355
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100104,FF:0101518,FF:0101524
|comment=
|comment=
|created_by=
|created_by=
|creation_date=
|creation_date=
|data_phase=2
|datafreeze_phase=2
|def=
|def=
|expression_enrichment_score=chr11:111249993..111250006,-!p1@POU2AF1!2.44!272.73!POU2AF1;;chr6:391743..391759,+!p1@IRF4!2.25!178.66!IRF4;;chr13:36788658..36788703,-!p2@CCDC169-SOHLH2,p2@SOHLH2!2.04!109.91!SOHLH2;;chr2:68592406..68592424,+!p1@PLEK!1.79!60.80!PLEK;;chr19:50922187..50922204,+!p1@SPIB!1.78!59.53!SPIB;;chr4:53206..53260,+!p1@ZNF595,p1@ZNF718!1.74!488.06!ZNF595;;chr7:28610099..28610113,+!p5@CREB5!1.69!47.84!CREB5;;chr8:72756637..72756664,-!p3@MSC!1.63!47.50!MSC;;chr8:72756667..72756736,-!p2@MSC!1.50!47.33!MSC;;chr14:75988771..75988826,+!p1@BATF!1.49!39.46!BATF;;chr1:25291475..25291511,-!p2@RUNX3!1.45!27.35!RUNX3;;chr19:36204309..36204335,+!p1@ZBTB32!1.39!23.45!ZBTB32;;chr17:8027418..8027432,-!p1@HES7!1.37!22.61!HES7;;chr17:38020392..38020477,-!p1@IKZF3!1.37!22.27!IKZF3;;chr9:37034469..37034474,-!p1@PAX5!1.33!20.49!PAX5;;chr1:25256756..25256774,-!p1@RUNX3!1.32!37.17!RUNX3;;chr17:42295777..42295816,-!p7@UBTF!1.32!23.79!UBTF;;chr1:23857698..23857733,-!p1@E2F2!1.26!31.08!E2F2;;chr2:231090433..231090469,+!p1@SP140!1.23!16.17!SP140;;chr9:126774018..126774055,+!p1@LHX2!1.23!16.00!LHX2;;chr2:68592394..68592405,+!p2@PLEK!1.19!14.65!PLEK;;chr9:126773880..126773895,+!p2@LHX2!1.19!14.39!LHX2;;chr7:50348268..50348366,+!p4@IKZF1!1.12!12.28!IKZF1;;chrY:21906594..21906622,-!p1@KDM5D!1.11!12.02!KDM5D;;chr13:41593425..41593480,-!p1@ELF1!1.10!73.58!ELF1;;chr11:61520075..61520136,+!p1@C11orf9!1.09!23.88!C11orf9;;chr19:50432453..50432468,+!p1@ATF5!1.08!610.49!ATF5;;chr20:42295745..42295765,+!p1@MYBL2!1.07!177.14!MYBL2;;chr15:76629123..76629151,+!p1@ISL2!1.05!11.35!ISL2;;chr2:231090471..231090504,+!p2@SP140!1.05!10.33!SP140;;chr16:85932760..85932775,+!p1@IRF8!1.05!10.16!IRF8;;chr5:158526917..158526932,-!p1@EBF1!0.99!22.35!EBF1;;chr20:42295713..42295738,+!p2@MYBL2!0.98!52.24!MYBL2;;chr17:41623692..41623715,-!p1@ETV4!0.97!37.00!ETV4;;chr18:52989031..52989079,-!p2@TCF4!0.96!19.73!TCF4;;chr5:142780189..142780223,-!p6@NR3C1!0.96!8.04!NR3C1;;chr6:34204973..34204990,+!p4@HMGA1!0.95!109.65!HMGA1;;chr12:7079780..7079791,-!p2@PHB2!0.95!43.27!PHB2;;chr7:28610060..28610073,+!p9@CREB5!0.95!7.87!CREB5;;chr20:42543441..42543497,+!p1@TOX2!0.94!35.65!TOX2;;chr3:101546827..101546847,+!p2@NFKBIZ!0.94!11.09!NFKBIZ;;chr7:128577972..128578047,+!p1@IRF5!0.93!11.94!IRF5;;chr17:41739283..41739297,-!p1@MEOX1!0.93!7.45!MEOX1;;chr7:156803329..156803362,-!p1@MNX1!0.92!7.28!MNX1;;chr5:138609782..138609826,+!p5@MATR3!0.91!48.60!MATR3;;chr11:19262421..19262455,-!p3@E2F8!0.90!7.03!E2F8;;chr9:16728161..16728185,-!p4@BNC2!0.90!6.94!BNC2;;chr18:55102598..55102623,+!p1@ONECUT2!0.90!6.94!ONECUT2;;chr17:41622765..41622821,-!p2@ETV4!0.89!10.50!ETV4;;chr1:212873267..212873332,-!p1@BATF3!0.89!9.31!BATF3;;chr14:75988831..75988847,+!p2@BATF!0.89!6.69!BATF;;chr3:141747459..141747475,-!p1@TFDP2!0.88!57.83!TFDP2;;chr6:108910863..108910912,+!p8@FOXO3!0.88!6.60!FOXO3;;chr17:42295897..42295953,-!p10@UBTF!0.87!8.81!UBTF;;chr5:142780237..142780261,-!p7@NR3C1!0.85!6.01!NR3C1;;chr1:25291620..25291635,-!p4@RUNX3!0.84!5.93!RUNX3;;chr15:60884706..60884743,-!p1@RORA!0.82!31.08!RORA;;chr18:52989001..52989030,-!p10@TCF4!0.82!6.18!TCF4;;chr1:8763440..8763460,-!p2@RERE!0.81!29.55!RERE;;chr17:41277372..41277418,-!p1@BRCA1!0.81!21.00!BRCA1;;chr15:74833584..74833626,+!p1@ARID3B!0.81!13.46!ARID3B;;chr17:42295682..42295731,-!p17@UBTF!0.81!5.42!UBTF;;chr18:55102628..55102646,+!p2@ONECUT2!0.80!5.33!ONECUT2;;chr15:96875657..96875760,+!p14@NR2F2!0.79!8.81!NR2F2;;chrX:131623026..131623039,-!p5@MBNL3!0.79!5.17!MBNL3;;chr5:88178983..88179012,-!p1@MEF2C!0.78!42.51!MEF2C;;chr19:42636586..42636607,-!p1@POU2F2!0.78!14.99!POU2F2;;chr9:117150254..117150271,-!p1@AKNA!0.78!14.82!AKNA;;chr2:185463247..185463263,+!p1@ZNF804A!0.78!9.40!ZNF804A;;chr16:85936412..85936431,+!p2@IRF8!0.77!4.91!IRF8;;chr6:135502501..135502546,+!p1@MYB!0.76!5.84!MYB;;chr19:13213662..13213686,-!p1@LYL1!0.75!7.11!LYL1;;chr7:28452130..28452154,+!p10@CREB5!0.75!4.57!CREB5;;chr14:74226961..74227020,-!p1@C14orf43!0.74!32.77!C14orf43;;chr6:43337180..43337244,-!p1@ZNF318!0.74!19.05!ZNF318;;chr6:43337124..43337144,-!p4@ZNF318!0.74!6.69!ZNF318;;chr12:54778471..54778528,-!p1@ZNF385A!0.74!4.49!ZNF385A;;chr13:41593493..41593506,-!p8@ELF1!0.74!4.49!ELF1;;chr9:16728327..16728338,-!p5@BNC2!0.74!4.49!BNC2;;chr8:86089417..86089440,+!p2@E2F5!0.73!9.40!E2F5;;chr8:86089627..86089653,+!p3@E2F5!0.73!5.00!E2F5;;chr13:36788718..36788729,-!p3@CCDC169-SOHLH2,p3@SOHLH2!0.73!4.40!SOHLH2;;chr5:158526756..158526797,-!p3@EBF1!0.73!4.32!EBF1;;chr10:104154246..104154347,+!p3@NFKB2!0.72!29.13!NFKB2;;chr5:76383070..76383117,-!p3@ZBED3!0.72!9.23!ZBED3;;chr4:185395590..185395627,-!p3@IRF2!0.72!5.42!IRF2;;chr17:41622925..41622976,-!p3@ETV4!0.71!6.44!ETV4;;chr2:231090344..231090361,-!p3@SP110!0.70!3.98!SP110;;chr17:41623009..41623053,-!p4@ETV4!0.69!6.69!ETV4;;chr5:158527104..158527135,-!p4@EBF1!0.69!3.89!EBF1;;chrX:106960285..106960299,-!p1@TSC22D3!0.68!117.95!TSC22D3;;chr6:135502408..135502459,+!p2@MYB!0.68!4.49!MYB;;chr13:114238997..114239077,+!p1@TFDP1!0.67!215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|ffid_belonging_in_development=CL:0000134,CL:0000051
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Line 35: Line 41:
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|microRNAs=
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|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10808
|name=hereditary spherocytic anemia cell line:WIL2-NS
|name=hereditary spherocytic anemia cell line:WIL2-NS
|namespace=FANTOM5
|namespace=FANTOM5
Line 42: Line 60:
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|rna_box=111
|rna_box=111
|rna_catalog_number=
|rna_catalog_number=
Line 57: Line 78:
|rna_weight_ug=82.25188
|rna_weight_ug=82.25188
|sample_age=unknown
|sample_age=unknown
|sample_category=cell lines
|sample_cell_catalog=jcrb9063
|sample_cell_catalog=jcrb9063
|sample_cell_line=WIL2-NS
|sample_cell_line=WIL2-NS
Line 69: Line 91:
|sample_ethnicity=C
|sample_ethnicity=C
|sample_experimental_condition=
|sample_experimental_condition=
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.1659210637718e-253!GO:0043227;membrane-bound organelle;1.25478846547953e-213!GO:0043231;intracellular membrane-bound organelle;2.30116738965771e-213!GO:0043226;organelle;1.43824292316926e-209!GO:0043229;intracellular organelle;5.75275469163444e-209!GO:0044422;organelle part;3.64922003465075e-181!GO:0044446;intracellular organelle part;3.08091320514021e-179!GO:0005737;cytoplasm;2.67779571742899e-178!GO:0032991;macromolecular complex;1.05875464086872e-142!GO:0044444;cytoplasmic part;2.03688196548923e-126!GO:0030529;ribonucleoprotein complex;4.80523340331533e-113!GO:0044428;nuclear part;1.03331028071782e-108!GO:0044237;cellular metabolic process;9.45387636632071e-105!GO:0043233;organelle lumen;4.28225799077855e-102!GO:0031974;membrane-enclosed lumen;4.28225799077855e-102!GO:0044238;primary metabolic process;3.46884889582173e-100!GO:0003723;RNA binding;8.28039003334458e-99!GO:0005634;nucleus;2.15949506473022e-97!GO:0005739;mitochondrion;4.76731384543825e-91!GO:0043170;macromolecule metabolic process;6.2430484721562e-89!GO:0043234;protein complex;1.9566539928953e-74!GO:0006396;RNA processing;1.68758361770825e-72!GO:0006412;translation;5.46937286752537e-71!GO:0005515;protein binding;1.65105825800996e-67!GO:0031981;nuclear lumen;1.28954284369027e-64!GO:0005840;ribosome;3.59978635471998e-64!GO:0044429;mitochondrial part;4.11979916936207e-61!GO:0003735;structural constituent of ribosome;7.07549970609847e-56!GO:0009058;biosynthetic process;8.79868239007659e-56!GO:0044249;cellular biosynthetic process;1.62690563354488e-55!GO:0031967;organelle envelope;1.91009207397871e-54!GO:0031975;envelope;4.93878880311911e-54!GO:0016071;mRNA metabolic process;3.24958300098277e-53!GO:0009059;macromolecule biosynthetic process;1.05850541383855e-52!GO:0006259;DNA metabolic process;5.41453734337826e-52!GO:0019538;protein metabolic process;6.69421666972244e-52!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.05021332313168e-51!GO:0043283;biopolymer metabolic process;1.02848722377427e-50!GO:0031090;organelle membrane;1.5912710137962e-49!GO:0033279;ribosomal subunit;2.28315804390306e-48!GO:0010467;gene expression;2.7906013822332e-47!GO:0008380;RNA splicing;2.1996776587689e-46!GO:0044267;cellular protein metabolic process;3.61549238579072e-46!GO:0006397;mRNA processing;3.87870807178165e-46!GO:0044260;cellular macromolecule metabolic process;6.94663309701952e-46!GO:0022613;ribonucleoprotein complex biogenesis and assembly;5.45588475942735e-45!GO:0043228;non-membrane-bound organelle;4.82840281264516e-44!GO:0043232;intracellular non-membrane-bound organelle;4.82840281264516e-44!GO:0016043;cellular component organization and biogenesis;1.1359568662712e-43!GO:0006996;organelle organization and biogenesis;3.76001524671953e-43!GO:0005654;nucleoplasm;1.00546943340912e-39!GO:0065003;macromolecular complex assembly;1.19431960217864e-39!GO:0033036;macromolecule localization;1.02381315120935e-38!GO:0005829;cytosol;1.22944625275429e-38!GO:0007049;cell cycle;6.9776553183574e-38!GO:0005740;mitochondrial envelope;5.12098220112409e-37!GO:0015031;protein transport;3.12680046479337e-36!GO:0019866;organelle inner membrane;2.54568029541481e-35!GO:0022607;cellular component assembly;8.14753332960522e-35!GO:0005681;spliceosome;1.64109096722784e-34!GO:0046907;intracellular transport;1.95625828868959e-34!GO:0031966;mitochondrial membrane;2.72278520018035e-34!GO:0008104;protein localization;4.13635254334319e-34!GO:0045184;establishment of protein localization;6.43823124553028e-34!GO:0006974;response to DNA damage stimulus;1.20142517407817e-33!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.78027999633535e-33!GO:0005743;mitochondrial inner membrane;6.10653567203019e-33!GO:0006886;intracellular protein transport;7.85418172641106e-32!GO:0000166;nucleotide binding;1.09385542234002e-31!GO:0044445;cytosolic part;9.71359906339413e-31!GO:0022402;cell cycle process;1.02448980261313e-30!GO:0003676;nucleic acid binding;1.70426682290181e-30!GO:0044451;nucleoplasm part;4.46491976964152e-30!GO:0006281;DNA repair;4.47957148588211e-30!GO:0005694;chromosome;5.07363823667931e-29!GO:0031980;mitochondrial lumen;9.7900076551397e-29!GO:0005759;mitochondrial matrix;9.7900076551397e-29!GO:0000278;mitotic cell cycle;7.05694397240808e-28!GO:0022403;cell cycle phase;5.58503015514785e-27!GO:0005730;nucleolus;6.87378088185728e-27!GO:0044427;chromosomal part;3.75389394079996e-26!GO:0044455;mitochondrial membrane part;9.10893858612744e-26!GO:0015935;small ribosomal subunit;5.07883616150992e-25!GO:0006119;oxidative phosphorylation;5.09243817331543e-25!GO:0000087;M phase of mitotic cell cycle;1.12591721366976e-24!GO:0051649;establishment of cellular localization;1.69999487914791e-24!GO:0015934;large ribosomal subunit;1.71546905956993e-24!GO:0007067;mitosis;1.87244745423671e-24!GO:0051641;cellular localization;3.89364532472532e-24!GO:0051276;chromosome organization and biogenesis;9.05482591935783e-24!GO:0000279;M phase;9.05482591935783e-24!GO:0022618;protein-RNA complex assembly;1.49972705038008e-23!GO:0009719;response to endogenous stimulus;6.49533990586557e-23!GO:0016462;pyrophosphatase activity;9.62270388827732e-23!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.16749196192145e-22!GO:0042254;ribosome biogenesis and assembly;1.49866388868501e-22!GO:0016817;hydrolase activity, acting on acid anhydrides;1.50242469224651e-22!GO:0017111;nucleoside-triphosphatase activity;1.57260920126635e-22!GO:0006260;DNA replication;1.22901632086969e-21!GO:0017076;purine nucleotide binding;2.06207069125913e-21!GO:0016874;ligase activity;2.66780050452544e-21!GO:0051301;cell division;3.08910973368918e-21!GO:0032553;ribonucleotide binding;7.36892709017851e-21!GO:0032555;purine ribonucleotide binding;7.36892709017851e-21!GO:0044265;cellular macromolecule catabolic process;1.06889066522841e-20!GO:0030554;adenyl nucleotide binding;1.10368485688142e-20!GO:0006457;protein folding;1.32320276256827e-20!GO:0032559;adenyl ribonucleotide binding;2.45807246683072e-20!GO:0005524;ATP binding;2.79708232596876e-20!GO:0005761;mitochondrial ribosome;5.64626040381433e-20!GO:0000313;organellar ribosome;5.64626040381433e-20!GO:0000502;proteasome complex (sensu Eukaryota);8.51228817811093e-20!GO:0005746;mitochondrial respiratory chain;8.57477336145952e-20!GO:0012505;endomembrane system;1.19270522113297e-19!GO:0016887;ATPase activity;1.79961927715034e-19!GO:0042623;ATPase activity, coupled;2.33754508023276e-19!GO:0008135;translation factor activity, nucleic acid binding;3.34430770166272e-19!GO:0051186;cofactor metabolic process;7.39713261850318e-19!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;3.25680332272504e-18!GO:0006512;ubiquitin cycle;4.03207411288224e-18!GO:0016070;RNA metabolic process;4.75978918613225e-18!GO:0006605;protein targeting;5.72455618908027e-18!GO:0044248;cellular catabolic process;6.4869454525155e-18!GO:0005635;nuclear envelope;7.2344689134929e-18!GO:0031965;nuclear membrane;1.08235507772852e-17!GO:0000398;nuclear mRNA splicing, via spliceosome;2.50028182475637e-17!GO:0000375;RNA splicing, via transesterification reactions;2.50028182475637e-17!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;2.50028182475637e-17!GO:0050136;NADH dehydrogenase (quinone) activity;2.66020051272642e-17!GO:0003954;NADH dehydrogenase activity;2.66020051272642e-17!GO:0008137;NADH dehydrogenase (ubiquinone) activity;2.66020051272642e-17!GO:0008134;transcription factor binding;3.24902238358242e-17!GO:0043285;biopolymer catabolic process;3.42781197478154e-17!GO:0009057;macromolecule catabolic process;3.52727438006836e-17!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);4.14908626137487e-17!GO:0019941;modification-dependent protein catabolic process;8.43577056958086e-17!GO:0043632;modification-dependent macromolecule catabolic process;8.43577056958086e-17!GO:0006511;ubiquitin-dependent protein catabolic process;1.0190940606221e-16!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.04070015011512e-16!GO:0006325;establishment and/or maintenance of chromatin architecture;1.04484767443638e-16!GO:0051603;proteolysis involved in cellular protein catabolic process;1.20776271035788e-16!GO:0044453;nuclear membrane part;1.83370625625198e-16!GO:0006399;tRNA metabolic process;3.18455663025551e-16!GO:0044257;cellular protein catabolic process;3.26771289051423e-16!GO:0012501;programmed cell death;3.91074455742777e-16!GO:0006323;DNA packaging;3.91074455742777e-16!GO:0006915;apoptosis;3.9871736525362e-16!GO:0042775;organelle ATP synthesis coupled electron transport;6.07541516510702e-16!GO:0042773;ATP synthesis coupled electron transport;6.07541516510702e-16!GO:0006732;coenzyme metabolic process;1.24297636293879e-15!GO:0006913;nucleocytoplasmic transport;1.66721955640795e-15!GO:0006364;rRNA processing;1.73035836550507e-15!GO:0030964;NADH dehydrogenase complex (quinone);2.64037348398915e-15!GO:0045271;respiratory chain complex I;2.64037348398915e-15!GO:0005747;mitochondrial respiratory chain complex I;2.64037348398915e-15!GO:0004386;helicase activity;3.97196378208305e-15!GO:0016072;rRNA metabolic process;4.69149788960475e-15!GO:0051169;nuclear transport;4.88115487968489e-15!GO:0016604;nuclear body;5.1545177719985e-15!GO:0003743;translation initiation factor activity;6.05550794707217e-15!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;7.78054681895897e-15!GO:0050657;nucleic acid transport;7.88866490863934e-15!GO:0051236;establishment of RNA localization;7.88866490863934e-15!GO:0050658;RNA transport;7.88866490863934e-15!GO:0005643;nuclear pore;8.58907555865235e-15!GO:0006403;RNA localization;9.17496307878365e-15!GO:0008219;cell death;1.66247188710054e-14!GO:0016265;death;1.66247188710054e-14!GO:0044432;endoplasmic reticulum part;1.74977596345214e-14!GO:0006413;translational initiation;1.87463663195963e-14!GO:0051082;unfolded protein binding;2.2541698620717e-14!GO:0043412;biopolymer modification;4.10333016799721e-14!GO:0008026;ATP-dependent helicase activity;1.21265918199496e-13!GO:0051726;regulation of cell cycle;1.22498382477915e-13!GO:0065002;intracellular protein transport across a membrane;1.43798740796352e-13!GO:0000074;regulation of progression through cell cycle;1.71159728811554e-13!GO:0005783;endoplasmic reticulum;2.03563623061112e-13!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;4.28924507736296e-13!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;8.37856121240897e-13!GO:0051028;mRNA transport;9.93150985459487e-13!GO:0046930;pore complex;1.0435060732359e-12!GO:0030163;protein catabolic process;2.83181513677978e-12!GO:0009055;electron carrier activity;2.91440359573253e-12!GO:0003712;transcription cofactor activity;3.114967828113e-12!GO:0006446;regulation of translational initiation;3.20092316174493e-12!GO:0009259;ribonucleotide metabolic process;3.95615373045155e-12!GO:0048770;pigment granule;4.5078143649732e-12!GO:0042470;melanosome;4.5078143649732e-12!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;4.66460357441976e-12!GO:0042175;nuclear envelope-endoplasmic reticulum network;4.88494058202148e-12!GO:0006163;purine nucleotide metabolic process;5.59006245335848e-12!GO:0000785;chromatin;6.77463425687554e-12!GO:0016779;nucleotidyltransferase activity;6.99901183428283e-12!GO:0005789;endoplasmic reticulum membrane;7.73849216317893e-12!GO:0017038;protein import;8.92430046923756e-12!GO:0006464;protein modification process;1.4112845726919e-11!GO:0006261;DNA-dependent DNA replication;1.48809997520851e-11!GO:0016568;chromatin modification;1.76070256470538e-11!GO:0065004;protein-DNA complex assembly;2.12769007601259e-11!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;2.62617478639854e-11!GO:0004812;aminoacyl-tRNA ligase activity;2.62617478639854e-11!GO:0016875;ligase activity, forming carbon-oxygen bonds;2.62617478639854e-11!GO:0006164;purine nucleotide biosynthetic process;2.62997720949725e-11!GO:0016607;nuclear speck;3.11055419896735e-11!GO:0009260;ribonucleotide biosynthetic process;3.97140376143866e-11!GO:0006333;chromatin assembly or disassembly;6.1164957154482e-11!GO:0043038;amino acid activation;6.86389275397495e-11!GO:0006418;tRNA aminoacylation for protein translation;6.86389275397495e-11!GO:0043039;tRNA aminoacylation;6.86389275397495e-11!GO:0000775;chromosome, pericentric region;8.23220470273289e-11!GO:0030532;small nuclear ribonucleoprotein complex;9.8168936017856e-11!GO:0006461;protein complex assembly;1.12037788357265e-10!GO:0009150;purine ribonucleotide metabolic process;1.1593638276763e-10!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.36265971877782e-10!GO:0051188;cofactor biosynthetic process;1.38600736476436e-10!GO:0042981;regulation of apoptosis;1.46841714201945e-10!GO:0003697;single-stranded DNA binding;1.51537721440788e-10!GO:0009056;catabolic process;1.6845455393058e-10!GO:0043566;structure-specific DNA binding;1.82118648316944e-10!GO:0043067;regulation of programmed cell death;2.29871185465995e-10!GO:0048193;Golgi vesicle transport;4.29500385248574e-10!GO:0016787;hydrolase activity;4.35078595755448e-10!GO:0009152;purine ribonucleotide biosynthetic process;5.60206451813912e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;6.04470280766882e-10!GO:0043687;post-translational protein modification;7.40481974157794e-10!GO:0009060;aerobic respiration;1.73539936685484e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;2.31509694725526e-09!GO:0051246;regulation of protein metabolic process;2.65127289806625e-09!GO:0008565;protein transporter activity;3.4483725244311e-09!GO:0005819;spindle;5.1261843711998e-09!GO:0009108;coenzyme biosynthetic process;5.83952096107298e-09!GO:0015078;hydrogen ion transmembrane transporter activity;6.40069781238244e-09!GO:0009117;nucleotide metabolic process;6.51305716095571e-09!GO:0003899;DNA-directed RNA polymerase activity;7.18712547104826e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;9.00084320104395e-09!GO:0009141;nucleoside triphosphate metabolic process;9.36092885536174e-09!GO:0009199;ribonucleoside triphosphate metabolic process;9.65042408480081e-09!GO:0045333;cellular respiration;1.1182768611958e-08!GO:0005839;proteasome core complex (sensu Eukaryota);1.45462155137513e-08!GO:0007005;mitochondrion organization and biogenesis;1.45687451217589e-08!GO:0019829;cation-transporting ATPase activity;1.50102869422847e-08!GO:0015986;ATP synthesis coupled proton transport;1.60101223933668e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.60101223933668e-08!GO:0009142;nucleoside triphosphate biosynthetic process;2.00104684154193e-08!GO:0009201;ribonucleoside triphosphate biosynthetic process;2.00104684154193e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;2.12870531766506e-08!GO:0009144;purine nucleoside triphosphate metabolic process;2.12870531766506e-08!GO:0008639;small protein conjugating enzyme activity;2.33731894759992e-08!GO:0005794;Golgi apparatus;2.91339254358217e-08!GO:0006099;tricarboxylic acid cycle;3.48368644457995e-08!GO:0046356;acetyl-CoA catabolic process;3.48368644457995e-08!GO:0005657;replication fork;3.55446224755191e-08!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;4.59503935999422e-08!GO:0009145;purine nucleoside triphosphate biosynthetic process;4.59503935999422e-08!GO:0006752;group transfer coenzyme metabolic process;4.90077050717846e-08!GO:0006084;acetyl-CoA metabolic process;5.16663365102969e-08!GO:0004842;ubiquitin-protein ligase activity;5.44362489261058e-08!GO:0046034;ATP metabolic process;5.92869298546291e-08!GO:0015630;microtubule cytoskeleton;6.49526183832517e-08!GO:0008094;DNA-dependent ATPase activity;6.52649174386796e-08!GO:0004298;threonine endopeptidase activity;6.56922399098016e-08!GO:0051168;nuclear export;7.61685675571728e-08!GO:0005813;centrosome;8.08911216607254e-08!GO:0019787;small conjugating protein ligase activity;8.19289244119693e-08!GO:0000075;cell cycle checkpoint;8.97249778220738e-08!GO:0006754;ATP biosynthetic process;9.37421772634273e-08!GO:0006753;nucleoside phosphate metabolic process;9.37421772634273e-08!GO:0016740;transferase activity;9.43575474642288e-08!GO:0051325;interphase;1.14224189935023e-07!GO:0006606;protein import into nucleus;1.20470094545372e-07!GO:0051329;interphase of mitotic cell cycle;1.20858382248121e-07!GO:0045259;proton-transporting ATP synthase complex;1.3316215233865e-07!GO:0051170;nuclear import;1.34247612883986e-07!GO:0000245;spliceosome assembly;1.3458214759138e-07!GO:0005815;microtubule organizing center;1.43911092571526e-07!GO:0007051;spindle organization and biogenesis;1.69199756343933e-07!GO:0006310;DNA recombination;2.2973384876203e-07!GO:0003713;transcription coactivator activity;2.88055223106966e-07!GO:0005667;transcription factor complex;3.72102681723827e-07!GO:0016881;acid-amino acid ligase activity;4.109255955622e-07!GO:0007088;regulation of mitosis;4.34123650129613e-07!GO:0009109;coenzyme catabolic process;4.53601104586722e-07!GO:0051187;cofactor catabolic process;4.59135717814983e-07!GO:0007059;chromosome segregation;4.81896432635561e-07!GO:0015077;monovalent inorganic cation transmembrane transporter activity;5.8114143584893e-07!GO:0006888;ER to Golgi vesicle-mediated transport;6.61987384082648e-07!GO:0005762;mitochondrial large ribosomal subunit;6.61987384082648e-07!GO:0000315;organellar large ribosomal subunit;6.61987384082648e-07!GO:0016469;proton-transporting two-sector ATPase complex;6.77891015874636e-07!GO:0008033;tRNA processing;8.41976383099802e-07!GO:0031202;RNA splicing factor activity, transesterification mechanism;9.05245533603726e-07!GO:0031497;chromatin assembly;9.61697360141569e-07!GO:0006334;nucleosome assembly;1.00213292523412e-06!GO:0000314;organellar small ribosomal subunit;1.32921293342564e-06!GO:0005763;mitochondrial small ribosomal subunit;1.32921293342564e-06!GO:0006793;phosphorus metabolic process;1.37337916643487e-06!GO:0006796;phosphate metabolic process;1.37337916643487e-06!GO:0006302;double-strand break repair;1.48284399779373e-06!GO:0006366;transcription from RNA polymerase II promoter;1.54189348742776e-06!GO:0006916;anti-apoptosis;1.55085178391364e-06!GO:0003724;RNA helicase activity;1.7964160853103e-06!GO:0009165;nucleotide biosynthetic process;2.09593098521468e-06!GO:0043069;negative regulation of programmed cell death;2.11370323630944e-06!GO:0032446;protein modification by small protein conjugation;2.11370323630944e-06!GO:0005793;ER-Golgi intermediate compartment;2.11370323630944e-06!GO:0016363;nuclear matrix;2.33006519051734e-06!GO:0016310;phosphorylation;2.41400586067627e-06!GO:0044452;nucleolar part;2.42898094825017e-06!GO:0043066;negative regulation of apoptosis;2.68964934795791e-06!GO:0006091;generation of precursor metabolites and energy;2.77297207548168e-06!GO:0004518;nuclease activity;2.99040950609047e-06!GO:0016491;oxidoreductase activity;3.27972513941705e-06!GO:0043623;cellular protein complex assembly;3.2898961605057e-06!GO:0016567;protein ubiquitination;4.06441439233388e-06!GO:0048475;coated membrane;4.23476869162116e-06!GO:0030117;membrane coat;4.23476869162116e-06!GO:0006520;amino acid metabolic process;4.24709109924936e-06!GO:0030120;vesicle coat;4.30776304252466e-06!GO:0030662;coated vesicle membrane;4.30776304252466e-06!GO:0003729;mRNA binding;5.87835799492492e-06!GO:0006401;RNA catabolic process;6.21386611531312e-06!GO:0019752;carboxylic acid metabolic process;6.44363981537395e-06!GO:0006082;organic acid metabolic process;6.95979861510664e-06!GO:0016192;vesicle-mediated transport;7.30502173173094e-06!GO:0016741;transferase activity, transferring one-carbon groups;7.47398504241556e-06!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;8.82326247214276e-06!GO:0015399;primary active transmembrane transporter activity;8.82326247214276e-06!GO:0006613;cotranslational protein targeting to membrane;1.12398642468656e-05!GO:0008168;methyltransferase activity;1.12457972516955e-05!GO:0000151;ubiquitin ligase complex;1.2035098317295e-05!GO:0006417;regulation of translation;1.22760598982971e-05!GO:0019899;enzyme binding;1.27699068276896e-05!GO:0007249;I-kappaB kinase/NF-kappaB cascade;1.43891611209729e-05!GO:0031072;heat shock protein binding;1.47847923803433e-05!GO:0004527;exonuclease activity;1.90325151877516e-05!GO:0051427;hormone receptor binding;1.91706440153684e-05!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;2.08200343598541e-05!GO:0043021;ribonucleoprotein binding;2.08625177074768e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;2.0870987022271e-05!GO:0016563;transcription activator activity;2.17047271675391e-05!GO:0030880;RNA polymerase complex;2.26927635931308e-05!GO:0006402;mRNA catabolic process;2.52236096823214e-05!GO:0008654;phospholipid biosynthetic process;3.1559273204818e-05!GO:0000776;kinetochore;3.28941819655066e-05!GO:0006352;transcription initiation;3.36154369533136e-05!GO:0051052;regulation of DNA metabolic process;3.57581575187576e-05!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;3.63885513049796e-05!GO:0003684;damaged DNA binding;3.91392479044676e-05!GO:0003678;DNA helicase activity;4.11889914200667e-05!GO:0035257;nuclear hormone receptor binding;4.16885752835938e-05!GO:0003714;transcription corepressor activity;4.38627617357846e-05!GO:0003690;double-stranded DNA binding;4.38636407664915e-05!GO:0005768;endosome;4.53904389210452e-05!GO:0003682;chromatin binding;4.97429808972773e-05!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;5.14120443728259e-05!GO:0016564;transcription repressor activity;5.17052070102697e-05!GO:0000049;tRNA binding;5.52790754207124e-05!GO:0005753;mitochondrial proton-transporting ATP synthase complex;5.5917584929437e-05!GO:0055029;nuclear DNA-directed RNA polymerase complex;5.5917584929437e-05!GO:0000428;DNA-directed RNA polymerase complex;5.5917584929437e-05!GO:0016251;general RNA polymerase II transcription factor activity;5.95373591168007e-05!GO:0046483;heterocycle metabolic process;6.22186782809118e-05!GO:0005770;late endosome;6.65970774655113e-05!GO:0045786;negative regulation of progression through cell cycle;6.74627062205504e-05!GO:0006414;translational elongation;7.01819987961054e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;7.14213196245227e-05!GO:0051252;regulation of RNA metabolic process;8.2362120284364e-05!GO:0043681;protein import into mitochondrion;8.39204782618192e-05!GO:0006405;RNA export from nucleus;8.44024468170255e-05!GO:0006612;protein targeting to membrane;8.63825537339424e-05!GO:0000079;regulation of cyclin-dependent protein kinase activity;8.68770641142214e-05!GO:0006626;protein targeting to mitochondrion;9.20540775194663e-05!GO:0008186;RNA-dependent ATPase activity;9.21919105349907e-05!GO:0008632;apoptotic program;0.000105724872284549!GO:0005758;mitochondrial intermembrane space;0.000106233526294196!GO:0016853;isomerase activity;0.000109565420213945!GO:0031326;regulation of cellular biosynthetic process;0.000113545829737165!GO:0006383;transcription from RNA polymerase III promoter;0.000125285946914639!GO:0009451;RNA modification;0.000132163294639245!GO:0050662;coenzyme binding;0.000134655992970017!GO:0031970;organelle envelope lumen;0.000140103833929204!GO:0007006;mitochondrial membrane organization and biogenesis;0.000142652927382535!GO:0000082;G1/S transition of mitotic cell cycle;0.000176628167398386!GO:0043492;ATPase activity, coupled to movement of substances;0.000188755284068685!GO:0043065;positive regulation of apoptosis;0.000201660094218113!GO:0006950;response to stress;0.000202976961931941!GO:0000228;nuclear chromosome;0.000222180151530596!GO:0007093;mitotic cell cycle checkpoint;0.000226368357734388!GO:0006839;mitochondrial transport;0.00024813979292494!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000248571935119403!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000252023570148459!GO:0004004;ATP-dependent RNA helicase activity;0.000267425846187337!GO:0043068;positive regulation of programmed cell death;0.000275987606503507!GO:0005684;U2-dependent spliceosome;0.000280768668251843!GO:0005885;Arp2/3 protein complex;0.000302365460758576!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000310857602125063!GO:0032508;DNA duplex unwinding;0.000336841310476572!GO:0032392;DNA geometric change;0.000336841310476572!GO:0065009;regulation of a molecular function;0.000356249690401742!GO:0045454;cell redox homeostasis;0.000362890871358824!GO:0046474;glycerophospholipid biosynthetic process;0.000398792578948684!GO:0048523;negative regulation of cellular process;0.000402756549388132!GO:0007052;mitotic spindle organization and biogenesis;0.000408261603309243!GO:0015992;proton transport;0.000418321632402539!GO:0006818;hydrogen transport;0.000418475434173429!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.000473420341557463!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.000473420341557463!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00047384829107801!GO:0009112;nucleobase metabolic process;0.000475282657662913!GO:0000059;protein import into nucleus, docking;0.000487015585605508!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000498509838998052!GO:0043596;nuclear replication fork;0.000509795296266273!GO:0030384;phosphoinositide metabolic process;0.000521681214473172!GO:0046489;phosphoinositide biosynthetic process;0.000572792576580169!GO:0042802;identical protein binding;0.000648006594168053!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000667070529742645!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000667070529742645!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000667070529742645!GO:0031968;organelle outer membrane;0.000691548198769004!GO:0006519;amino acid and derivative metabolic process;0.000745056591303566!GO:0006268;DNA unwinding during replication;0.000753128445085446!GO:0015980;energy derivation by oxidation of organic compounds;0.000762062121419841!GO:0019867;outer membrane;0.000806161479727052!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.000807727014201534!GO:0005798;Golgi-associated vesicle;0.000824151442283579!GO:0006650;glycerophospholipid metabolic process;0.000829220189419972!GO:0004576;oligosaccharyl transferase activity;0.000829740663799362!GO:0006611;protein export from nucleus;0.000847988089171311!GO:0006270;DNA replication initiation;0.000859002356281464!GO:0016859;cis-trans isomerase activity;0.000905393007355791!GO:0000178;exosome (RNase complex);0.000969287222393039!GO:0043488;regulation of mRNA stability;0.00098556819668824!GO:0043487;regulation of RNA stability;0.00098556819668824!GO:0050794;regulation of cellular process;0.000986052204606337!GO:0051920;peroxiredoxin activity;0.000995487980296496!GO:0019843;rRNA binding;0.0010083340053011!GO:0005048;signal sequence binding;0.00102110313282268!GO:0030658;transport vesicle membrane;0.00103676450953642!GO:0006289;nucleotide-excision repair;0.00103976340862663!GO:0000786;nucleosome;0.00109316594540332!GO:0009889;regulation of biosynthetic process;0.00109527171999818!GO:0003725;double-stranded RNA binding;0.00112219632294836!GO:0000070;mitotic sister chromatid segregation;0.00117077531586561!GO:0048037;cofactor binding;0.00117493060620419!GO:0009116;nucleoside metabolic process;0.00118155457395126!GO:0005741;mitochondrial outer membrane;0.00119505320361211!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.00121552703454585!GO:0006144;purine base metabolic process;0.00121703761675234!GO:0031124;mRNA 3'-end processing;0.00123573119383749!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00128920845721673!GO:0000819;sister chromatid segregation;0.00129037415548279!GO:0051539;4 iron, 4 sulfur cluster binding;0.00133146001530631!GO:0044431;Golgi apparatus part;0.0013739079931582!GO:0044454;nuclear chromosome part;0.00137666801227416!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00138799045756133!GO:0008250;oligosaccharyl transferase complex;0.00140477895931471!GO:0008408;3'-5' exonuclease activity;0.00141587354440359!GO:0003711;transcription elongation regulator activity;0.00143947930587934!GO:0004532;exoribonuclease activity;0.00146716697687763!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.00146716697687763!GO:0009124;nucleoside monophosphate biosynthetic process;0.00150631869502232!GO:0009123;nucleoside monophosphate metabolic process;0.00150631869502232!GO:0003746;translation elongation factor activity;0.00153303370038749!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.00159801672278022!GO:0022890;inorganic cation transmembrane transporter activity;0.00160200081516918!GO:0003887;DNA-directed DNA polymerase activity;0.00163200681775311!GO:0042393;histone binding;0.00163805513271488!GO:0000096;sulfur amino acid metabolic process;0.0016760258300618!GO:0048500;signal recognition particle;0.00169137333302596!GO:0005788;endoplasmic reticulum lumen;0.0017250680300197!GO:0051540;metal cluster binding;0.00175893231930795!GO:0051536;iron-sulfur cluster binding;0.00175893231930795!GO:0006338;chromatin remodeling;0.00175893231930795!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00178515980601651!GO:0043284;biopolymer biosynthetic process;0.00184227428742501!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00189441589769419!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00190042951740998!GO:0006917;induction of apoptosis;0.00190592947281756!GO:0000922;spindle pole;0.00197784536558601!GO:0016272;prefoldin complex;0.00198178850055502!GO:0008312;7S RNA binding;0.00199741014694597!GO:0006118;electron transport;0.00210832133485626!GO:0005769;early endosome;0.00217412818482566!GO:0032200;telomere organization and biogenesis;0.00231142558353122!GO:0000723;telomere maintenance;0.00231142558353122!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00235037649117455!GO:0048519;negative regulation of biological process;0.00235037649117455!GO:0008139;nuclear localization sequence binding;0.00235037649117455!GO:0005637;nuclear inner membrane;0.00236947582604469!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00241978223560924!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00245776863371968!GO:0012502;induction of programmed cell death;0.00251587026103739!GO:0030660;Golgi-associated vesicle membrane;0.00264291739425512!GO:0006284;base-excision repair;0.00274363271408765!GO:0043601;nuclear replisome;0.00274363271408765!GO:0030894;replisome;0.00274363271408765!GO:0051087;chaperone binding;0.00280255705427276!GO:0005876;spindle microtubule;0.00284279078527309!GO:0000793;condensed chromosome;0.00289489184146795!GO:0044440;endosomal part;0.00289489184146795!GO:0010008;endosome membrane;0.00289489184146795!GO:0009081;branched chain family amino acid metabolic process;0.00297585492107866!GO:0004003;ATP-dependent DNA helicase activity;0.00310950544433278!GO:0000725;recombinational repair;0.00313665606986643!GO:0000724;double-strand break repair via homologous recombination;0.00313665606986643!GO:0008180;signalosome;0.00320998047782182!GO:0030118;clathrin coat;0.00330458086712943!GO:0006506;GPI anchor biosynthetic process;0.00356692230948852!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00372690932238614!GO:0045047;protein targeting to ER;0.00372690932238614!GO:0005669;transcription factor TFIID complex;0.00378849394435172!GO:0018196;peptidyl-asparagine modification;0.00380403327047605!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00380403327047605!GO:0006595;polyamine metabolic process;0.00380403327047605!GO:0009161;ribonucleoside monophosphate metabolic process;0.00380403327047605!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.00380403327047605!GO:0006007;glucose catabolic process;0.00382582443112108!GO:0000287;magnesium ion binding;0.00386399571319988!GO:0000339;RNA cap binding;0.00392468510237622!GO:0031123;RNA 3'-end processing;0.00397580101179301!GO:0006275;regulation of DNA replication;0.00398976119915762!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00411345768933141!GO:0007243;protein kinase cascade;0.00411345768933141!GO:0005663;DNA replication factor C complex;0.0041756322906189!GO:0048471;perinuclear region of cytoplasm;0.00418230542761158!GO:0032259;methylation;0.0044129775327528!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0044222620592098!GO:0042770;DNA damage response, signal transduction;0.00442963396244029!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.00451187127053718!GO:0006505;GPI anchor metabolic process;0.00452450760941746!GO:0030521;androgen receptor signaling pathway;0.00472317344216428!GO:0033116;ER-Golgi intermediate compartment membrane;0.00481199734192506!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00481199734192506!GO:0015002;heme-copper terminal oxidase activity;0.00481199734192506!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00481199734192506!GO:0004129;cytochrome-c oxidase activity;0.00481199734192506!GO:0007010;cytoskeleton organization and biogenesis;0.00490422700895438!GO:0043022;ribosome binding;0.00494011550489958!GO:0022411;cellular component disassembly;0.00509301511559526!GO:0008652;amino acid biosynthetic process;0.00569371494871286!GO:0005525;GTP binding;0.00578147719713417!GO:0030518;steroid hormone receptor signaling pathway;0.00578987559094896!GO:0046128;purine ribonucleoside metabolic process;0.00581669129957524!GO:0042278;purine nucleoside metabolic process;0.00581669129957524!GO:0046966;thyroid hormone receptor binding;0.00603501026772234!GO:0047485;protein N-terminus binding;0.00607110753769504!GO:0003924;GTPase activity;0.00607507961252857!GO:0000152;nuclear ubiquitin ligase complex;0.00635449267329293!GO:0009303;rRNA transcription;0.0066859030166128!GO:0000726;non-recombinational repair;0.00686001137842495!GO:0031570;DNA integrity checkpoint;0.0068762752845969!GO:0046467;membrane lipid biosynthetic process;0.00693198635610596!GO:0006497;protein amino acid lipidation;0.00701892351711596!GO:0006400;tRNA modification;0.00702433188821638!GO:0044450;microtubule organizing center part;0.00722430698000399!GO:0006406;mRNA export from nucleus;0.00725783180149343!GO:0019783;small conjugating protein-specific protease activity;0.00748782388951018!GO:0008234;cysteine-type peptidase activity;0.00761703822443362!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.00768613018306109!GO:0007017;microtubule-based process;0.00769994262230992!GO:0016126;sterol biosynthetic process;0.00771576025192828!GO:0005832;chaperonin-containing T-complex;0.00780453025091494!GO:0000175;3'-5'-exoribonuclease activity;0.00788898340917309!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.00818997312131169!GO:0006891;intra-Golgi vesicle-mediated transport;0.00819404477526786!GO:0035258;steroid hormone receptor binding;0.00822033503505063!GO:0000097;sulfur amino acid biosynthetic process;0.00832591669711644!GO:0051789;response to protein stimulus;0.00836797512771269!GO:0006986;response to unfolded protein;0.00836797512771269!GO:0046365;monosaccharide catabolic process;0.00857151848053538!GO:0006220;pyrimidine nucleotide metabolic process;0.00861907680726812!GO:0016584;nucleosome positioning;0.00875736890652441!GO:0043414;biopolymer methylation;0.00877955160169782!GO:0016408;C-acyltransferase activity;0.00890138171347502!GO:0008022;protein C-terminus binding;0.0089630344275822!GO:0000139;Golgi membrane;0.00922061026916021!GO:0016788;hydrolase activity, acting on ester bonds;0.00946068308104826!GO:0006378;mRNA polyadenylation;0.00958477455464873!GO:0009119;ribonucleoside metabolic process;0.00966237617330028!GO:0000781;chromosome, telomeric region;0.00988413798299547!GO:0006730;one-carbon compound metabolic process;0.0101473424035082!GO:0015631;tubulin binding;0.0105117549481888!GO:0006695;cholesterol biosynthetic process;0.0106385821230875!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.0107896319066894!GO:0004843;ubiquitin-specific protease activity;0.0108213269929996!GO:0006733;oxidoreduction coenzyme metabolic process;0.0108440986210584!GO:0006740;NADPH regeneration;0.0109037381792905!GO:0006098;pentose-phosphate shunt;0.0109037381792905!GO:0009083;branched chain family amino acid catabolic process;0.0110369771765241!GO:0008610;lipid biosynthetic process;0.0113273683488529!GO:0004540;ribonuclease activity;0.0115033998774923!GO:0048522;positive regulation of cellular process;0.0116652662260411!GO:0006807;nitrogen compound metabolic process;0.0116739155349781!GO:0046112;nucleobase biosynthetic process;0.0118575913676671!GO:0009615;response to virus;0.011960441029445!GO:0046164;alcohol catabolic process;0.0123585695281611!GO:0006376;mRNA splice site selection;0.0124341651571923!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0124341651571923!GO:0004674;protein serine/threonine kinase activity;0.0126285460943025!GO:0050790;regulation of catalytic activity;0.012688005747554!GO:0030867;rough endoplasmic reticulum membrane;0.0127126541382406!GO:0019079;viral genome replication;0.0127342041561715!GO:0022415;viral reproductive process;0.0128337889626302!GO:0035267;NuA4 histone acetyltransferase complex;0.0131118966603348!GO:0031577;spindle checkpoint;0.0132025470160291!GO:0009308;amine metabolic process;0.0132937331523762!GO:0051287;NAD binding;0.0137326731596005!GO:0030132;clathrin coat of coated pit;0.0139383992194024!GO:0030119;AP-type membrane coat adaptor complex;0.0139541012791762!GO:0019320;hexose catabolic process;0.0141064434822817!GO:0016790;thiolester hydrolase activity;0.0142800540618924!GO:0000119;mediator complex;0.0142975982198634!GO:0018193;peptidyl-amino acid modification;0.0144397517282716!GO:0043189;H4/H2A histone acetyltransferase complex;0.0149672728391501!GO:0008276;protein methyltransferase activity;0.015095695414463!GO:0033170;DNA-protein loading ATPase activity;0.0153185588183085!GO:0003689;DNA clamp loader activity;0.0153185588183085!GO:0016407;acetyltransferase activity;0.0156652554909681!GO:0019222;regulation of metabolic process;0.0157546145045676!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0158326414647082!GO:0005773;vacuole;0.0162706423123709!GO:0030833;regulation of actin filament polymerization;0.0163348630236941!GO:0030125;clathrin vesicle coat;0.0165673590220455!GO:0030665;clathrin coated vesicle membrane;0.0165673590220455!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0166947162137512!GO:0000323;lytic vacuole;0.0167216865726542!GO:0005764;lysosome;0.0167216865726542!GO:0008637;apoptotic mitochondrial changes;0.0167458354988374!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0167831352665928!GO:0008538;proteasome activator activity;0.017017866287835!GO:0005732;small nucleolar ribonucleoprotein complex;0.0171636791662774!GO:0030131;clathrin adaptor complex;0.0171636791662774!GO:0005874;microtubule;0.0176908801578761!GO:0004221;ubiquitin thiolesterase activity;0.0178279194023641!GO:0030663;COPI coated vesicle membrane;0.0181318175722193!GO:0030126;COPI vesicle coat;0.0181318175722193!GO:0000910;cytokinesis;0.0182931055887272!GO:0007021;tubulin folding;0.0185017171150402!GO:0015036;disulfide oxidoreductase activity;0.0185296143756733!GO:0007050;cell cycle arrest;0.0186913284322983!GO:0009066;aspartate family amino acid metabolic process;0.0188663023762956!GO:0042158;lipoprotein biosynthetic process;0.0188806048965902!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0190223621375562!GO:0045039;protein import into mitochondrial inner membrane;0.0190223621375562!GO:0030262;apoptotic nuclear changes;0.0190921795840253!GO:0031324;negative regulation of cellular metabolic process;0.0194582055924579!GO:0001522;pseudouridine synthesis;0.0200198191262034!GO:0046822;regulation of nucleocytoplasmic transport;0.0201342766831612!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0201410761984366!GO:0030134;ER to Golgi transport vesicle;0.0201874926126276!GO:0006308;DNA catabolic process;0.0203826260714564!GO:0006607;NLS-bearing substrate import into nucleus;0.0206318321068624!GO:0009067;aspartate family amino acid biosynthetic process;0.0208940621002989!GO:0032404;mismatch repair complex binding;0.0211311261852836!GO:0033673;negative regulation of kinase activity;0.0211311261852836!GO:0006469;negative regulation of protein kinase activity;0.0211311261852836!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0212192478066892!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.021469954094185!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.021469954094185!GO:0009126;purine nucleoside monophosphate metabolic process;0.021469954094185!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.021469954094185!GO:0022884;macromolecule transmembrane transporter activity;0.0214857242774034!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0214857242774034!GO:0030036;actin cytoskeleton organization and biogenesis;0.0219318991185526!GO:0008320;protein transmembrane transporter activity;0.0219318991185526!GO:0004448;isocitrate dehydrogenase activity;0.0221690139473676!GO:0051053;negative regulation of DNA metabolic process;0.0221741654951939!GO:0051348;negative regulation of transferase activity;0.0224863964133984!GO:0009396;folic acid and derivative biosynthetic process;0.0226410428100522!GO:0030041;actin filament polymerization;0.0238843935062227!GO:0043624;cellular protein complex disassembly;0.0240592362702377!GO:0000077;DNA damage checkpoint;0.0244567336025197!GO:0006643;membrane lipid metabolic process;0.0245459063288777!GO:0031647;regulation of protein stability;0.0245459063288777!GO:0005851;eukaryotic translation initiation factor 2B complex;0.0249011446337335!GO:0006301;postreplication repair;0.0251295089366026!GO:0009967;positive regulation of signal transduction;0.0252152121425687!GO:0051090;regulation of transcription factor activity;0.0262870945372776!GO:0051223;regulation of protein transport;0.0263167408726286!GO:0004523;ribonuclease H activity;0.0264344108594497!GO:0000118;histone deacetylase complex;0.0269570576449734!GO:0001824;blastocyst development;0.0270550336271661!GO:0006778;porphyrin metabolic process;0.0270963765331625!GO:0033013;tetrapyrrole metabolic process;0.0270963765331625!GO:0006415;translational termination;0.0271167178222808!GO:0000123;histone acetyltransferase complex;0.0271167178222808!GO:0003756;protein disulfide isomerase activity;0.0274565358740593!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0274565358740593!GO:0007004;telomere maintenance via telomerase;0.0276362054862582!GO:0000792;heterochromatin;0.0284062372585664!GO:0045069;regulation of viral genome replication;0.0290548542549768!GO:0044262;cellular carbohydrate metabolic process;0.0292408826323509!GO:0030127;COPII vesicle coat;0.0292828608531935!GO:0012507;ER to Golgi transport vesicle membrane;0.0292828608531935!GO:0008097;5S rRNA binding;0.0294511123733962!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0301803441704398!GO:0010257;NADH dehydrogenase complex assembly;0.0301803441704398!GO:0033108;mitochondrial respiratory chain complex assembly;0.0301803441704398!GO:0006644;phospholipid metabolic process;0.0301803441704398!GO:0009070;serine family amino acid biosynthetic process;0.0301803441704398!GO:0008536;Ran GTPase binding;0.0305505861782785!GO:0008299;isoprenoid biosynthetic process;0.0306013369479261!GO:0043621;protein self-association;0.0311151572931919!GO:0032561;guanyl ribonucleotide binding;0.0312136990549183!GO:0019001;guanyl nucleotide binding;0.0312136990549183!GO:0030176;integral to endoplasmic reticulum membrane;0.031291754387066!GO:0004536;deoxyribonuclease activity;0.0315502896087377!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0315611622336342!GO:0031625;ubiquitin protein ligase binding;0.0318064057731524!GO:0043281;regulation of caspase activity;0.0320554453817961!GO:0032984;macromolecular complex disassembly;0.0321807277594998!GO:0009113;purine base biosynthetic process;0.0328746149633296!GO:0001832;blastocyst growth;0.0328795184754428!GO:0030508;thiol-disulfide exchange intermediate activity;0.0330064665934092!GO:0019206;nucleoside kinase activity;0.0335265651432815!GO:0006739;NADP metabolic process;0.0337222991338857!GO:0016197;endosome transport;0.0340818948276116!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0342904472974558!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0343726250604314!GO:0005680;anaphase-promoting complex;0.0343811024071276!GO:0006096;glycolysis;0.0347183627361855!GO:0000209;protein polyubiquitination;0.0350929403507662!GO:0051320;S phase;0.0352472738429745!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.0353114757634638!GO:0006919;caspase activation;0.0354264392414966!GO:0045767;regulation of anti-apoptosis;0.0355462010207913!GO:0005869;dynactin complex;0.0357259404729753!GO:0031371;ubiquitin conjugating enzyme complex;0.0364518639647592!GO:0007094;mitotic cell cycle spindle assembly checkpoint;0.0366520656599192!GO:0006596;polyamine biosynthetic process;0.0368441097995491!GO:0008537;proteasome activator complex;0.0368539236694885!GO:0006278;RNA-dependent DNA replication;0.0368539236694885!GO:0044438;microbody part;0.0370260038725278!GO:0044439;peroxisomal part;0.0370260038725278!GO:0048487;beta-tubulin binding;0.0372356806684329!GO:0051092;activation of NF-kappaB transcription factor;0.0375087558217554!GO:0042769;DNA damage response, detection of DNA damage;0.0378409441438785!GO:0006767;water-soluble vitamin metabolic process;0.0378773603829643!GO:0005784;translocon complex;0.0379984776221108!GO:0030522;intracellular receptor-mediated signaling pathway;0.0379984776221108!GO:0004659;prenyltransferase activity;0.0382498832801381!GO:0050178;phenylpyruvate tautomerase activity;0.03831636876018!GO:0032405;MutLalpha complex binding;0.0383303601580151!GO:0019238;cyclohydrolase activity;0.0384681275257842!GO:0019210;kinase inhibitor activity;0.0384811081510459!GO:0006743;ubiquinone metabolic process;0.0384811081510459!GO:0006744;ubiquinone biosynthetic process;0.0384811081510459!GO:0042375;quinone cofactor metabolic process;0.0384811081510459!GO:0045426;quinone cofactor biosynthetic process;0.0384811081510459!GO:0051098;regulation of binding;0.0385221859427063!GO:0030374;ligand-dependent nuclear receptor transcription coactivator activity;0.0385732343390059!GO:0046426;negative regulation of JAK-STAT cascade;0.0385777047820286!GO:0017134;fibroblast growth factor binding;0.0387641029244089!GO:0045815;positive regulation of gene expression, epigenetic;0.0388759193781033!GO:0006769;nicotinamide metabolic process;0.0402750130063655!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0402750130063655!GO:0051297;centrosome organization and biogenesis;0.0402970835630149!GO:0031023;microtubule organizing center organization and biogenesis;0.0402970835630149!GO:0005095;GTPase inhibitor activity;0.0403401647554633!GO:0043433;negative regulation of transcription factor activity;0.0405030752571277!GO:0030130;clathrin coat of trans-Golgi network vesicle;0.0409496694018422!GO:0012510;trans-Golgi network transport vesicle membrane;0.0409496694018422!GO:0000288;mRNA catabolic process, deadenylation-dependent decay;0.0412980397384785!GO:0005652;nuclear lamina;0.0413266159459235!GO:0004177;aminopeptidase activity;0.0422782444919773!GO:0004239;methionyl aminopeptidase activity;0.0425356066550844!GO:0001891;phagocytic cup;0.0426636809669184!GO:0006303;double-strand break repair via nonhomologous end joining;0.0428071436566004!GO:0051235;maintenance of localization;0.0428466367041159!GO:0008017;microtubule binding;0.0428466367041159!GO:0006779;porphyrin biosynthetic process;0.0429460267079537!GO:0033014;tetrapyrrole biosynthetic process;0.0429460267079537!GO:0048468;cell development;0.0434675865286209!GO:0006563;L-serine metabolic process;0.0435198163120147!GO:0030137;COPI-coated vesicle;0.0435499983841151!GO:0043631;RNA polyadenylation;0.0436004589930968!GO:0008143;poly(A) binding;0.0440750378216961!GO:0004860;protein kinase inhibitor activity;0.0442519610240864!GO:0008213;protein amino acid alkylation;0.0442519610240864!GO:0006479;protein amino acid methylation;0.0442519610240864!GO:0031252;leading edge;0.0445468649054378!GO:0032039;integrator complex;0.0450746362233746!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.0463595274124055!GO:0019900;kinase binding;0.046558204278432!GO:0005658;alpha DNA polymerase:primase complex;0.0468284997230373!GO:0016417;S-acyltransferase activity;0.047170208117342!GO:0016569;covalent chromatin modification;0.0481121501519518!GO:0051656;establishment of organelle localization;0.0482099423630911!GO:0006564;L-serine biosynthetic process;0.0493965369628043!GO:0006379;mRNA cleavage;0.0495205861428352!GO:0005092;GDP-dissociation inhibitor activity;0.049655437256735!GO:0051338;regulation of transferase activity;0.04976558175668
|sample_id=10808
|sample_id=10808
|sample_note=
|sample_note=
Line 76: Line 99:
|sample_tissue=blood
|sample_tissue=blood
|top_motifs=ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:2.48907557667;MYB:1.96120311355;NFY{A,B,C}:1.83068116767;ELK1,4_GABP{A,B1}:1.81959343233;HOX{A6,A7,B6,B7}:1.78302997368;E2F1..5:1.7618279803;POU2F1..3:1.72819147132;YY1:1.63290865751;PBX1:1.53073640814;PAX3,7:1.48707198443;ELF1,2,4:1.44957260983;RXR{A,B,G}_{NR1H2,PPAR}dimers:1.38944075488;NRF1:1.29786280793;BREu{core}:1.29107722994;OCT4_SOX2{dimer}:1.25221011963;POU5F1:1.24931553069;AIRE:1.23001830093;ZNF143:1.147800517;GFI1:1.10961197665;PAX6:1.09236638746;PAX8:1.09143419056;CDX1,2,4:0.98681111789;NR5A1,2:0.855121089094;NKX6-1,2:0.841924439708;POU1F1:0.785680574602;RUNX1..3:0.770059433166;DMAP1_NCOR{1,2}_SMARC:0.748113675051;NANOG{mouse}:0.712411287724;FOXA2:0.706678864316;NFKB1_REL_RELA:0.694806650935;ZEB1:0.691423007887;IRF1,2:0.644388289267;SPI1:0.633173683457;PDX1:0.595005699586;SOX{8,9,10}:0.544998978687;FOXP3:0.497883937155;TFDP1:0.469208320849;PITX1..3:0.463365314893;ZBTB16:0.457544219344;RORA:0.455266426521;AHR_ARNT_ARNT2:0.420956763769;VSX1,2:0.414318100978;ADNP_IRX_SIX_ZHX:0.413281806042;ONECUT1,2:0.408358366967;ALX1:0.403870151357;CRX:0.388688799128;GATA6:0.379923552532;TOPORS:0.376222458864;bHLH_family:0.375768558193;PRRX1,2:0.347102324605;FOXN1:0.342670957615;CUX2:0.333311603564;GATA4:0.312326154061;POU6F1:0.299183149045;HOXA9_MEIS1:0.219374529573;POU3F1..4:0.215531760044;TGIF1:0.20097163676;NKX3-2:0.182248592242;IKZF2:0.181379079423;NKX3-1:0.175585253128;HNF4A_NR2F1,2:0.173727936513;SPIB:0.17255861979;ATF5_CREB3:0.134134045065;NFIL3:0.102314605421;ETS1,2:0.0956139534175;AR:0.0845067052481;IRF7:0.0626561108763;NANOG:0.0618234194948;TEF:0.0467180557665;HOX{A5,B5}:0.042297157966;FOXQ1:0.0221091812262;MYOD1:0.0173885734571;ZNF384:0.00320022677326;SOX17:0.00153502699948;ATF4:-0.00624437216424;TLX2:-0.0167028641959;CEBPA,B_DDIT3:-0.0263497904165;CDC5L:-0.0402933053903;ARID5B:-0.0517472794991;RFX1:-0.0535029614893;FOXP1:-0.0538288175994;RBPJ:-0.0572545687567;HSF1,2:-0.0848916547943;CREB1:-0.110045935929;PAX4:-0.119683126749;NFIX:-0.133748954424;HNF1A:-0.134720619772;ALX4:-0.139121746288;SNAI1..3:-0.145171013453;HAND1,2:-0.156789417525;LMO2:-0.159354619105;HIF1A:-0.173013936363;GFI1B:-0.176003625055;FOX{F1,F2,J1}:-0.188179373071;KLF4:-0.196151699742;MEF2{A,B,C,D}:-0.215800485887;IKZF1:-0.218436187525;PAX2:-0.219280045489;MYBL2:-0.247635942547;TAL1_TCF{3,4,12}:-0.247883761174;EVI1:-0.256322643279;NFE2:-0.256384936879;FOXM1:-0.25862323735;HOX{A4,D4}:-0.266642808319;FOSL2:-0.267934297706;T:-0.288560453688;STAT5{A,B}:-0.293313122873;HLF:-0.317579423381;NKX2-1,4:-0.354207135342;PRDM1:-0.393669539892;ESRRA:-0.397589237349;EN1,2:-0.403176109219;ZNF148:-0.407679221935;NKX2-3_NKX2-5:-0.41452016152;SRF:-0.457390746773;NKX2-2,8:-0.461968399819;EBF1:-0.467941831676;HES1:-0.469104703989;PPARG:-0.48832013126;UFEwm:-0.508877926114;ESR1:-0.525464439572;FOX{I1,J2}:-0.542991698542;NR6A1:-0.544490829442;FOS_FOS{B,L1}_JUN{B,D}:-0.545862274144;STAT2,4,6:-0.554268184795;RXR{A,B,G}:-0.559607908957;SPZ1:-0.563713871568;BPTF:-0.601053034652;BACH2:-0.62391805429;ZIC1..3:-0.634279842919;ZFP161:-0.642412514703;DBP:-0.643535300853;NFE2L2:-0.656166389013;GCM1,2:-0.658859373535;NR1H4:-0.665691457327;RFX2..5_RFXANK_RFXAP:-0.675044209686;FOXO1,3,4:-0.701222956763;HMGA1,2:-0.72313365772;LEF1_TCF7_TCF7L1,2:-0.730319814046;LHX3,4:-0.762433467858;SOX2:-0.763369287451;ATF2:-0.779336003964;NR3C1:-0.785077894618;SOX5:-0.810241333943;RXRA_VDR{dimer}:-0.813481428237;FOXD3:-0.819038023989;HBP1_HMGB_SSRP1_UBTF:-0.843756761958;TP53:-0.846295612245;NFE2L1:-0.940947450125;XBP1:-0.959769343325;NFATC1..3:-0.967740037191;MYFfamily:-0.988539790999;TBX4,5:-0.996886195493;SREBF1,2:-1.00207600722;MAFB:-1.00943433391;ZNF238:-1.01105111571;ZBTB6:-1.03563162447;RREB1:-1.0479343236;TBP:-1.05814511974;ZNF423:-1.05880323889;MZF1:-1.06429680497;TFAP4:-1.09921378439;GTF2I:-1.11434314307;NHLH1,2:-1.12258441105;REST:-1.12551765927;PAX1,9:-1.14074918678;JUN:-1.15339740077;TLX1..3_NFIC{dimer}:-1.16797407588;SMAD1..7,9:-1.17220985307;GTF2A1,2:-1.18834306295;EP300:-1.21428561113;TFCP2:-1.23718180538;TFAP2{A,C}:-1.24198702242;MED-1{core}:-1.25604629858;STAT1,3:-1.26838361933;FOXL1:-1.27714939525;HIC1:-1.31206782003;PAX5:-1.36758967756;MTE{core}:-1.37709645239;TEAD1:-1.40904648098;ATF6:-1.42014569171;GZF1:-1.42151027983;MTF1:-1.45100333828;XCPE1{core}:-1.48657529642;FOX{D1,D2}:-1.48989528923;PATZ1:-1.61320514425;GLI1..3:-1.71215641433;EGR1..3:-1.76496846441;MAZ:-1.76953690815;TFAP2B:-1.88512258443;HMX1:-2.00746546704;SP1:-2.31147318104
|top_motifs=ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:2.48907557667;MYB:1.96120311355;NFY{A,B,C}:1.83068116767;ELK1,4_GABP{A,B1}:1.81959343233;HOX{A6,A7,B6,B7}:1.78302997368;E2F1..5:1.7618279803;POU2F1..3:1.72819147132;YY1:1.63290865751;PBX1:1.53073640814;PAX3,7:1.48707198443;ELF1,2,4:1.44957260983;RXR{A,B,G}_{NR1H2,PPAR}dimers:1.38944075488;NRF1:1.29786280793;BREu{core}:1.29107722994;OCT4_SOX2{dimer}:1.25221011963;POU5F1:1.24931553069;AIRE:1.23001830093;ZNF143:1.147800517;GFI1:1.10961197665;PAX6:1.09236638746;PAX8:1.09143419056;CDX1,2,4:0.98681111789;NR5A1,2:0.855121089094;NKX6-1,2:0.841924439708;POU1F1:0.785680574602;RUNX1..3:0.770059433166;DMAP1_NCOR{1,2}_SMARC:0.748113675051;NANOG{mouse}:0.712411287724;FOXA2:0.706678864316;NFKB1_REL_RELA:0.694806650935;ZEB1:0.691423007887;IRF1,2:0.644388289267;SPI1:0.633173683457;PDX1:0.595005699586;SOX{8,9,10}:0.544998978687;FOXP3:0.497883937155;TFDP1:0.469208320849;PITX1..3:0.463365314893;ZBTB16:0.457544219344;RORA:0.455266426521;AHR_ARNT_ARNT2:0.420956763769;VSX1,2:0.414318100978;ADNP_IRX_SIX_ZHX:0.413281806042;ONECUT1,2:0.408358366967;ALX1:0.403870151357;CRX:0.388688799128;GATA6:0.379923552532;TOPORS:0.376222458864;bHLH_family:0.375768558193;PRRX1,2:0.347102324605;FOXN1:0.342670957615;CUX2:0.333311603564;GATA4:0.312326154061;POU6F1:0.299183149045;HOXA9_MEIS1:0.219374529573;POU3F1..4:0.215531760044;TGIF1:0.20097163676;NKX3-2:0.182248592242;IKZF2:0.181379079423;NKX3-1:0.175585253128;HNF4A_NR2F1,2:0.173727936513;SPIB:0.17255861979;ATF5_CREB3:0.134134045065;NFIL3:0.102314605421;ETS1,2:0.0956139534175;AR:0.0845067052481;IRF7:0.0626561108763;NANOG:0.0618234194948;TEF:0.0467180557665;HOX{A5,B5}:0.042297157966;FOXQ1:0.0221091812262;MYOD1:0.0173885734571;ZNF384:0.00320022677326;SOX17:0.00153502699948;ATF4:-0.00624437216424;TLX2:-0.0167028641959;CEBPA,B_DDIT3:-0.0263497904165;CDC5L:-0.0402933053903;ARID5B:-0.0517472794991;RFX1:-0.0535029614893;FOXP1:-0.0538288175994;RBPJ:-0.0572545687567;HSF1,2:-0.0848916547943;CREB1:-0.110045935929;PAX4:-0.119683126749;NFIX:-0.133748954424;HNF1A:-0.134720619772;ALX4:-0.139121746288;SNAI1..3:-0.145171013453;HAND1,2:-0.156789417525;LMO2:-0.159354619105;HIF1A:-0.173013936363;GFI1B:-0.176003625055;FOX{F1,F2,J1}:-0.188179373071;KLF4:-0.196151699742;MEF2{A,B,C,D}:-0.215800485887;IKZF1:-0.218436187525;PAX2:-0.219280045489;MYBL2:-0.247635942547;TAL1_TCF{3,4,12}:-0.247883761174;EVI1:-0.256322643279;NFE2:-0.256384936879;FOXM1:-0.25862323735;HOX{A4,D4}:-0.266642808319;FOSL2:-0.267934297706;T:-0.288560453688;STAT5{A,B}:-0.293313122873;HLF:-0.317579423381;NKX2-1,4:-0.354207135342;PRDM1:-0.393669539892;ESRRA:-0.397589237349;EN1,2:-0.403176109219;ZNF148:-0.407679221935;NKX2-3_NKX2-5:-0.41452016152;SRF:-0.457390746773;NKX2-2,8:-0.461968399819;EBF1:-0.467941831676;HES1:-0.469104703989;PPARG:-0.48832013126;UFEwm:-0.508877926114;ESR1:-0.525464439572;FOX{I1,J2}:-0.542991698542;NR6A1:-0.544490829442;FOS_FOS{B,L1}_JUN{B,D}:-0.545862274144;STAT2,4,6:-0.554268184795;RXR{A,B,G}:-0.559607908957;SPZ1:-0.563713871568;BPTF:-0.601053034652;BACH2:-0.62391805429;ZIC1..3:-0.634279842919;ZFP161:-0.642412514703;DBP:-0.643535300853;NFE2L2:-0.656166389013;GCM1,2:-0.658859373535;NR1H4:-0.665691457327;RFX2..5_RFXANK_RFXAP:-0.675044209686;FOXO1,3,4:-0.701222956763;HMGA1,2:-0.72313365772;LEF1_TCF7_TCF7L1,2:-0.730319814046;LHX3,4:-0.762433467858;SOX2:-0.763369287451;ATF2:-0.779336003964;NR3C1:-0.785077894618;SOX5:-0.810241333943;RXRA_VDR{dimer}:-0.813481428237;FOXD3:-0.819038023989;HBP1_HMGB_SSRP1_UBTF:-0.843756761958;TP53:-0.846295612245;NFE2L1:-0.940947450125;XBP1:-0.959769343325;NFATC1..3:-0.967740037191;MYFfamily:-0.988539790999;TBX4,5:-0.996886195493;SREBF1,2:-1.00207600722;MAFB:-1.00943433391;ZNF238:-1.01105111571;ZBTB6:-1.03563162447;RREB1:-1.0479343236;TBP:-1.05814511974;ZNF423:-1.05880323889;MZF1:-1.06429680497;TFAP4:-1.09921378439;GTF2I:-1.11434314307;NHLH1,2:-1.12258441105;REST:-1.12551765927;PAX1,9:-1.14074918678;JUN:-1.15339740077;TLX1..3_NFIC{dimer}:-1.16797407588;SMAD1..7,9:-1.17220985307;GTF2A1,2:-1.18834306295;EP300:-1.21428561113;TFCP2:-1.23718180538;TFAP2{A,C}:-1.24198702242;MED-1{core}:-1.25604629858;STAT1,3:-1.26838361933;FOXL1:-1.27714939525;HIC1:-1.31206782003;PAX5:-1.36758967756;MTE{core}:-1.37709645239;TEAD1:-1.40904648098;ATF6:-1.42014569171;GZF1:-1.42151027983;MTF1:-1.45100333828;XCPE1{core}:-1.48657529642;FOX{D1,D2}:-1.48989528923;PATZ1:-1.61320514425;GLI1..3:-1.71215641433;EGR1..3:-1.76496846441;MAZ:-1.76953690815;TFAP2B:-1.88512258443;HMX1:-2.00746546704;SP1:-2.31147318104
|xref=
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10808-111A7;search_select_hide=table117:FF:10808-111A7
}}
}}

Latest revision as of 15:06, 3 June 2020

Name:hereditary spherocytic anemia cell line:WIL2-NS
Species:Human (Homo sapiens)
Library ID:CNhs11891
Sample type:cell lines
Genomic View: UCSC
RefEX:Specific genes
CAGEd-oPOSSUM:link
ZENBU report :link
Additional information
Sample information
strainNA
tissueblood
dev stageNA
sexmale
ageunknown
cell typeb cell
cell lineWIL2-NS
companyJAPAN HEALTH SCIENCES FOUNDATION - Health Science Research Resources Bank
collaborationFANTOM5 OSC CORE (contact: Al Forrest)
External link for information[{{{sample_info_link}}} {{{sample_info_link}}}]
RNA information
lot numberNA
catalog numberNA
sample typetotal RNA
extraction protocol (Details)OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0

CAGE Accession numbers
MethodSample accession id
CAGE  SAMD00005140
Library accession numbers

Library idMethodExp. accession idRun accession id
CNhs11891 CAGE DRX007909 DRR008781
Accession ID Hg19

Library idBAMCTSS
CNhs11891 DRZ000206 DRZ001591
Accession ID Hg38

Library idBAMCTSS
CNhs11891 DRZ011556 DRZ012941
Download raw sequence, BAM & CTSS
Hg19
FastaBAMCTSS
downloaddownloaddonwload
Hg38
BAMCTSS
downloaddonwload


Relative expression to median (log10)

Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.



Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data

Coexpression clusterscore
C0-CD14-Eosinophils-Neutrophils-Basophils-CD34-immature-Peripheral0
C1-testis-epididymis-embryonic-medulla-pituitary-trachea-caudate0
C10-occipital-temporal-parietal-brain-duodenum-Neurons-Neural0
C100-rhabdomyosarcoma-gastric-pineal-Wilms-cervical-mesodermal-endometrial0
C101-small-cerebellum-maxillary-colon-parietal-epididymis-merkel0
C102-neuroblastoma-testicular-pituitary-carcinosarcoma-rectum-acantholytic-iPS0
C103-CD4-CD8-Natural-Peripheral-Whole-Neutrophils-Basophils0
C104-Mast-Basophils-immature-CD14-CD34-eye-Natural0
C105-heart-skeletal-occipital-hippocampus-acute-Sebocyte-penis0.131
C106-Hep2-epitheloid-placenta-cervical-rectal-anaplastic-glassy0
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C89-small-retinoblastoma-medulloblastoma-iPS-acantholytic-eye-bronchogenic0
C9-skeletal-diaphragm-tongue-throat-penis-heart-left0
C90-neuroectodermal-peripheral-neuroepithelioma-neuroblastoma-carcinoid-parietal-putamen0
C91-Fibroblast-Smooth-mesenchymal-Mesothelial-Small-Preadipocyte-Hair0
C92-CD14CD16-CD14-Eosinophils-Basophils-Neutrophils-Macrophage-Whole0
C93-chronic-acute-leukemia-acantholytic-medulloblastoma-testis-papillotubular0
C94-smallcell-adrenal-lung-nonsmall-small-somatostatinoma-teratocarcinoma0
C95-lung-aorta-trachea-penis-Alveolar-throat-endometrioid0
C96-non-acute-tonsil-spleen-Burkitt-lymphoma-appendix0
C97-small-smallcell-gastrointestinal-argyrophil-putamen-duodenum-brain0
C98-CD8-Natural-Basophils-blood-CD4-Peripheral-Whole0
C99-hairy-mycosis-submaxillary-salivary-cord-kidney-parotid0



Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data



TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample

JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs11891

Jaspar motifP-value
MA0002.20.074
MA0003.10.754
MA0004.10.034
MA0006.10.199
MA0007.10.277
MA0009.10.645
MA0014.10.593
MA0017.10.0866
MA0018.20.809
MA0019.10.148
MA0024.18.30168e-10
MA0025.10.567
MA0027.10.334
MA0028.13.862e-7
MA0029.10.416
MA0030.10.00157
MA0031.10.0438
MA0035.20.272
MA0038.10.0327
MA0039.20.373
MA0040.10.00984
MA0041.10.0919
MA0042.10.291
MA0043.10.426
MA0046.10.459
MA0047.20.299
MA0048.10.169
MA0050.11.40548e-7
MA0051.14.25855e-5
MA0052.10.764
MA0055.10.0123
MA0057.10.927
MA0058.10.0198
MA0059.11.59415e-4
MA0060.11.59835e-14
MA0061.10.0022
MA0062.22.33702e-11
MA0065.20.0186
MA0066.10.779
MA0067.10.697
MA0068.10.151
MA0069.10.282
MA0070.10.673
MA0071.10.611
MA0072.10.0602
MA0073.10.685
MA0074.10.557
MA0076.14.34502e-10
MA0077.10.377
MA0078.10.273
MA0079.20.119
MA0080.20.00179
MA0081.10.0349
MA0083.10.0323
MA0084.10.093
MA0087.10.0404
MA0088.15.37063e-4
MA0090.18.64946e-6
MA0091.10.567
MA0092.10.88
MA0093.10.0228
MA0099.20.00748
MA0100.10.0166
MA0101.10.0049
MA0102.20.154
MA0103.10.151
MA0104.26.7735e-5
MA0105.17.21916e-5
MA0106.10.344
MA0107.10.00649
MA0108.26.5201e-8
MA0111.10.498
MA0112.20.359
MA0113.10.756
MA0114.10.0123
MA0115.10.124
MA0116.12.69588e-4
MA0117.10.808
MA0119.10.799
MA0122.10.473
MA0124.10.603
MA0125.10.234
MA0131.10.0863
MA0135.10.602
MA0136.12.8387e-8
MA0137.20.238
MA0138.20.42
MA0139.10.0898
MA0140.10.0422
MA0141.10.0891
MA0142.10.0282
MA0143.10.188
MA0144.10.367
MA0145.10.452
MA0146.10.712
MA0147.12.48917e-5
MA0148.10.283
MA0149.10.154
MA0150.10.817
MA0152.10.286
MA0153.10.0528
MA0154.10.032
MA0155.10.659
MA0156.12.64166e-10
MA0157.10.818
MA0159.10.196
MA0160.10.496
MA0162.10.78
MA0163.12.00722e-10
MA0164.10.793
MA0258.10.409
MA0259.10.038



FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs11891

Novel motifP-value
10.00495
100.0165
1000.348
1010.0627
1020.661
1030.139
1040.359
1050.668
1060.341
1070.128
1080.883
1090.027
110.0724
1100.0967
1110.117
1120.923
1130.625
1140.505
1150.825
1160.648
1170.00884
1180.149
1190.185
120.993
1200.296
1210.674
1220.504
1230.0085
1240.107
1250.391
1260.315
1270.104
1280.275
1290.502
130.0439
1300.283
1310.378
1320.104
1330.531
1340.513
1350.559
1360.182
1370.819
1380.513
1390.516
140.953
1400.698
1410.0284
1420.989
1430.0978
1440.559
1450.258
1460.894
1470.967
1480.0981
1490.306
150.0352
1500.998
1510.616
1520.0388
1530.998
1540.641
1550.322
1560.796
1570.146
1580.968
1590.248
160.961
1600.224
1610.0553
1620.772
1630.439
1640.266
1650.868
1660.482
1670.0728
1680.537
1690.937
170.981
180.185
190.783
20.596
200.378
210.128
220.894
230.0328
240.308
250.213
260.0276
270.688
280.302
290.00882
30.111
300.156
310.969
320.395
330.304
340.352
350.061
360.0392
370.307
380.559
390.327
40.137
400.264
410.754
420.0485
430.592
440.0901
450.431
460.179
470.0173
480.112
490.272
50.976
500.744
510.742
520.083
530.611
540.774
550.745
560.696
570.226
580.314
590.777
60.774
600.671
610.057
620.303
630.813
640.176
650.764
660.00604
670.275
680.0269
690.704
70.0972
700.54
710.0178
720.564
730.901
740.792
750.00307
760.474
770.749
780.272
790.0537
80.068
800.458
810.227
820.658
830.149
840.917
850.29
860.251
870.182
880.705
890.636
90.578
900.124
910.0314
920.683
930.332
940.243
950.0137
960.554
970.142
980.311
990.817



de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br> library id: CNhs11891


FANTOM5 (FF) ontology

Direct parent terms


Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data

CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0002371 (somatic cell)
0000542 (lymphocyte)
0000219 (motile cell)
0000945 (lymphocyte of B lineage)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0002242 (nucleate cell)
0000255 (eukaryotic cell)

DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
2531 (hematologic cancer)
0060058 (lymphoma)
14566 (disease of cellular proliferation)
0060083 (immune system cancer)
1287 (cardiovascular system disease)
7 (disease of anatomical entity)
74 (hematopoietic system disease)
2355 (anemia)

FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100104 (lymphoma cell line sample)
0101518 (B-lymphoma cell line sample)
0101524 (WIL2-NS cell sample)

Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)
CL:0000051 (common lymphoid progenitor)

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