FF:11553-120C5: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00004775 | ||
| | |accession_numbers=CAGE;DRX008287;DRR009159;DRZ000584;DRZ001969;DRZ011934;DRZ013319 | ||
| | |ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0002097,UBERON:0002199,UBERON:0002384,UBERON:0000479,UBERON:0000062,UBERON:0000061,UBERON:0000465,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0003102,UBERON:0002416 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0002320,CL:0002371,CL:0000255,CL:0000057,CL:0002620 | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000057,FF:0000250,FF:0000001 | ||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr1:197886461..197886558,+!p1@LHX9!2.48!299.46!LHX9;;chr12:54410664..54410684,+!p1@HOXC4,p1@HOXC5,p1@HOXC6!1.97!91.94!HOXC5;;chr10:28034739..28034756,-!p1@MKX!1.89!76.68!MKX;;chr6:134210243..134210257,+!p1@TCF21!1.85!69.79!TCF21;;chr9:132427883..132427951,+!p2@PRRX2!1.62!40.39!PRRX2;;chr11:46299199..46299233,+!p1@CREB3L1!1.56!176.81!CREB3L1;;chr1:170632285..170632309,+!p1@PRRX1!1.56!39.83!PRRX1;;chr7:19157248..19157268,-!p1@TWIST1!1.52!86.92!TWIST1;;chr9:132427972..132428056,+!p1@PRRX2!1.51!40.20!PRRX2;;chr7:27224795..27224840,-!p2@HOXA11!1.45!27.36!HOXA11;;chr7:27224842..27224872,-!p1@HOXA11!1.37!22.71!HOXA11;;chr2:239756671..239756732,+!p1@TWIST2!1.34!66.07!TWIST2;;chr15:57511609..57511651,+!p2@TCF12!1.32!33.31!TCF12;;chr12:54402745..54402788,+!p1@HOXC8!1.29!18.43!HOXC8;;chr2:239756739..239756755,+!p2@TWIST2!1.25!28.48!TWIST2;;chr1:170633348..170633399,+!p2@PRRX1!1.23!21.96!PRRX1;;chr4:174450089..174450153,-!p2@HAND2!1.20!14.70!HAND2;;chr5:72744594..72744609,-!p1@FOXD1!1.17!63.09!FOXD1;;chr11:46299539..46299620,+!p2@CREB3L1!1.17!23.08!CREB3L1;;chr12:54380404..54380433,+!p3@HOXC10!1.16!13.40!HOXC10;;chr12:54410639..54410659,+!p2@HOXC4,p2@HOXC5,p2@HOXC6!1.15!13.21!HOXC5;;chr12:53614115..53614154,-!p1@RARG!1.14!68.68!RARG;;chr6:10415276..10415341,-!p2@TFAP2A!1.14!15.82!TFAP2A;;chr19:47523058..47523114,+!p1@NPAS1!1.14!12.84!NPAS1;;chr1:170632959..170632987,+!p4@PRRX1!1.13!13.77!PRRX1;;chr5:2751762..2751784,-!p1@IRX2!1.12!12.28!IRX2;;chr12:54378923..54378966,+!p1@HOXC10!1.12!12.10!HOXC10;;chr4:174451370..174451387,-!p1@HAND2!1.10!11.54!HAND2;;chr10:119303078..119303169,+!p2@EMX2!1.09!11.35!EMX2;;chr12:54393880..54393962,+!p1@HOXC9!1.09!11.17!HOXC9;;chr2:19558373..19558392,-!p1@OSR1!1.07!29.96!OSR1;;chr1:170633262..170633285,+!p3@PRRX1!1.04!11.35!PRRX1;;chr8:93074803..93074845,-!p1@RUNX1T1!1.04!10.05!RUNX1T1;;chr2:176994408..176994492,+!p1@HOXD8!1.04!9.86!HOXD8;;chr3:157823517..157823562,-!p1@SHOX2!1.03!10.42!SHOX2;;chr7:44143925..44143970,+!p1@AEBP1!1.01!208.45!AEBP1;;chr18:53068911..53068935,-!p4@TCF4!1.01!10.42!TCF4;;chr10:28032421..28032494,-!p2@MKX!1.01!9.31!MKX;;chr10:28035133..28035148,-!p3@MKX!1.01!9.12!MKX;;chr1:197886665..197886732,+!p3@LHX9!0.99!8.75!LHX9;;chrY:21906594..21906622,-!p1@KDM5D!0.98!8.56!KDM5D;;chr5:321810..321877,+!p1@AHRR!0.97!26.99!AHRR;;chr19:13134772..13134822,+!p2@NFIX!0.97!12.28!NFIX;;chr1:170633058..170633084,+!p5@PRRX1!0.96!8.19!PRRX1;;chr1:197886421..197886432,+!p2@LHX9!0.96!8.19!LHX9;;chrY:2803415..2803468,+!p1@ZFY!0.95!7.82!ZFY;;chr6:19837592..19837621,+!p1@ID4!0.92!46.90!ID4;;chr10:28035112..28035130,-!p5@MKX!0.92!7.26!MKX;;chr3:147111231..147111281,+!p3@ZIC1!0.92!7.26!ZIC1;;chr20:55204351..55204377,+!p1@TFAP2C!0.90!8.93!TFAP2C;;chr8:60031934..60031986,-!p6@TOX!0.88!6.51!TOX;;chr12:54380036..54380091,+!p4@HOXC10!0.88!6.51!HOXC10;;chr10:63809013..63809041,+!p3@ARID5B!0.87!37.41!ARID5B;;chr8:60031619..60031676,-!p1@TOX!0.85!13.59!TOX;;chr5:72744445..72744466,-!p2@FOXD1!0.85!10.42!FOXD1;;chr7:27192185..27192209,-!p1@HOXA3!0.85!6.14!HOXA3;;chr1:119530493..119530572,-!p1@TBX15!0.85!6.14!TBX15;;chr1:170632477..170632506,+!p6@PRRX1!0.85!6.14!PRRX1;;chr7:44143978..44143989,+!p2@AEBP1!0.83!10.98!AEBP1;;chr6:10412600..10412637,-!p1@TFAP2A!0.83!9.86!TFAP2A;;chr7:27213893..27213954,-!p1@HOXA10!0.82!5.58!HOXA10;;chr1:170632115..170632136,+!p9@PRRX1!0.82!5.58!PRRX1;;chr16:31076332..31076388,-!p3@ZNF668!0.82!5.58!ZNF668;;chr7:27205136..27205164,-!p1@HOXA9!0.81!5.40!HOXA9;;chr14:75894714..75894733,+!p1@JDP2!0.80!163.22!JDP2;;chr14:24837368..24837401,+!p1@NFATC4!0.80!13.21!NFATC4;;chr8:67525443..67525459,-!p2@MYBL1!0.79!8.00!MYBL1;;chr12:54379029..54379057,+!p2@HOXC10!0.79!5.21!HOXC10;;chr8:60031809..60031835,-!p4@TOX!0.78!6.51!TOX;;chr12:54402790..54402805,+!p2@HOXC8!0.78!5.03!HOXC8;;chr3:147111198..147111225,+!p4@ZIC1!0.78!5.03!ZIC1;;chr3:147127142..147127168,+!p1@ZIC1!0.77!4.84!ZIC1;;chr8:60031682..60031710,-!p2@TOX!0.76!8.00!TOX;;chr4:81118647..81118666,+!p1@PRDM8!0.76!6.51!PRDM8;;chr16:86544113..86544145,+!p1@FOXF1!0.75!5.96!FOXF1;;chr1:170632723..170632739,+!p8@PRRX1!0.75!4.65!PRRX1;;chr2:119605214..119605230,-!p1@EN1!0.75!4.65!EN1;;chr3:25470156..25470227,+!p2@RARB!0.75!4.65!RARB;;chr4:111558135..111558198,-!p2@PITX2!0.75!4.65!PITX2;;chr15:37392724..37392757,-!p1@MEIS2!0.74!22.71!MEIS2;;chr18:22932080..22932170,-!p1@ZNF521!0.74!20.85!ZNF521;;chr7:42276787..42276815,-!p1@GLI3!0.73!12.84!GLI3;;chr7:19157043..19157088,-!p2@TWIST1!0.73!11.91!TWIST1;;chr5:158526917..158526932,-!p1@EBF1!0.73!11.73!EBF1;;chr19:13136130..13136165,+!p6@NFIX!0.73!5.96!NFIX;;chr1:54204818..54204870,-!p@chr1:54204818..54204870,-!0.73!4.65!GLIS1;;chr8:49833948..49833973,-!p2@SNAI2!0.72!30.15!SNAI2;;chr11:65687362..65687436,+!p3@DRAP1!0.72!21.78!DRAP1;;chr3:37217736..37217753,-!p2@LRRFIP2!0.72!19.73!LRRFIP2;;chr3:147127177..147127194,+!p2@ZIC1!0.72!4.28!ZIC1;;chr10:119302232..119302265,+!p1@EMX2!0.72!4.28!EMX2;;chr1:170632439..170632465,+!p11@PRRX1!0.72!4.28!PRRX1;;chr14:61116183..61116208,-!p1@SIX1!0.71!17.31!SIX1;;chr10:28035155..28035166,-!p8@MKX!0.71!4.09!MKX;;chr1:170632137..170632172,+!p10@PRRX1!0.71!4.09!PRRX1;;chr2:172949484..172949522,+!p1@DLX1!0.71!4.09!DLX1;;chr2:172967621..172967637,-!p1@DLX2!0.70!11.73!DLX2;;chr16:54320617..54320643,-!p3@IRX3!0.69!5.21!IRX3;;chr6:85473156..85473210,-!p2@TBX18!0.69!4.84!TBX18;;chr17:46132044..46132080,+!p4@NFE2L1!0.69!3.91!NFE2L1;;chr2:172950227..172950249,+!p2@DLX1!0.69!3.91!DLX1;;chr8:49833978..49833996,-!p1@SNAI2!0.68!88.78!SNAI2;;chr6:85474299..85474324,-!p1@TBX18!0.68!7.26!TBX18;;chr19:13134457..13134462,+!p5@NFIX!0.68!7.26!NFIX;;chr15:83953397..83953425,-!p1@BNC1!0.68!4.47!BNC1;;chr1:170632250..170632277,+!p7@PRRX1!0.67!3.72!PRRX1;;chr8:93115274..93115323,-!p4@RUNX1T1!0.67!3.72!RUNX1T1;;chr5:139487608..139487663,+!p3@PURA!0.66!8.38!PURA;;chr5:158526459..158526481,-!p2@EBF1!0.66!5.03!EBF1;;chr8:93074848..93074871,-!p3@RUNX1T1!0.66!3.54!RUNX1T1;;chr16:86612320..86612394,+!p1@FOXL1!0.66!3.54!FOXL1;;chr10:28034395..28034404,-!p9@MKX!0.66!3.54!MKX;;chr1:40105299..40105326,-!p1@HEYL!0.66!3.54!HEYL;;chr2:119604456..119604501,-!p2@EN1!0.66!3.54!EN1;;chr3:147110055..147110129,-!p1@ZIC4!0.66!3.54!ZIC4;;chr15:37392616..37392638,-!p2@MEIS2!0.65!12.28!MEIS2;;chr3:141121847..141121868,+!p5@ZBTB38!0.65!5.58!ZBTB38;;chr7:44143997..44144008,+!p3@AEBP1!0.65!4.65!AEBP1;;chr15:42749722..42749739,-!p2@ZFP106!0.64!6.51!ZFP106;;chr17:46806067..46806097,-!p1@HOXB13!0.64!3.35!HOXB13;;chr19:13135386..13135435,+!p4@NFIX!0.64!3.35!NFIX;;chr11:46299443..46299459,+!p4@CREB3L1!0.64!3.35!CREB3L1;;chr10:63809106..63809127,+!p1@ARID5B!0.62!50.62!ARID5B;;chr3:178789522..178789564,-!p2@ZMAT3!0.62!27.92!ZMAT3;;chr3:147111505..147111529,+!p6@ZIC1!0.62!3.16!ZIC1;;chr12:54394309..54394336,+!p2@HOXC9!0.62!3.16!HOXC9;;chr7:27239703..27239715,-!p1@HOXA13!0.62!3.16!HOXA13;;chr8:23564065..23564087,-!p1@NKX2-6!0.62!3.16!NKX2-6;;chr4:4861385..4861398,+!p1@MSX1!0.61!10.42!MSX1;;chr15:37390850..37390909,-!p3@MEIS2!0.61!6.70!MEIS2;;chr14:62162258..62162269,+!p2@HIF1A!0.60!34.43!HIF1A;;chr16:54964740..54964789,+!p1@IRX5!0.60!4.65!IRX5;;chr5:72744562..72744573,-!p3@FOXD1!0.60!3.91!FOXD1;;chr15:37392593..37392607,-!p13@MEIS2!0.60!3.72!MEIS2;;chr15:80843484..80843499,+!p5@ARNT2!0.60!2.98!ARNT2;;chr2:121493425..121493474,+!p1@GLI2!0.59!7.26!GLI2;;chr15:37390482..37390572,-!p7@MEIS2!0.59!4.28!MEIS2;;chr16:4366053..4366076,+!p@chr16:4366053..4366076,+!0.58!34.62!GLIS2;;chr15:57511589..57511608,+!p4@TCF12!0.58!2.79!TCF12;;chr5:139492456..139492489,+!p7@PURA!0.58!2.79!PURA;;chr5:3595977..3595999,+!p1@IRX1!0.58!2.79!IRX1;;chr7:27205106..27205134,-!p2@HOXA9!0.58!2.79!HOXA9;;chr8:60031840..60031869,-!p5@TOX!0.58!2.79!TOX;;chr12:54402729..54402743,+!p3@HOXC8!0.58!2.79!HOXC8;;chr12:54410948..54410992,+!p3@HOXC5!0.58!2.79!HOXC5;;chr2:172967242..172967265,-!p2@DLX2!0.58!2.79!DLX2;;chr2:172967323..172967336,-!p4@DLX2!0.58!2.79!DLX2;;chr2:46524537..46524553,+!p1@EPAS1!0.57!338.55!EPAS1;;chr12:80085061..80085119,-!p6@PAWR!0.57!4.84!PAWR;;chr19:31840130..31840160,-!p2@TSHZ3!0.57!4.65!TSHZ3;;chr8:60031762..60031803,-!p3@TOX!0.57!4.28!TOX;;chr2:200322654..200322707,-!p2@SATB2!0.57!4.28!SATB2;;chr16:54320101..54320125,-!p4@IRX3!0.56!4.09!IRX3;;chr11:12696071..12696086,+!p3@TEAD1!0.56!3.72!TEAD1;;chr15:37392534..37392562,-!p10@MEIS2!0.56!2.98!MEIS2;;chr12:53625846..53625861,-!p6@RARG!0.56!2.61!RARG;;chr5:142780189..142780223,-!p6@NR3C1!0.56!2.61!NR3C1;;chr1:170632907..170632916,+!p22@PRRX1!0.56!2.61!PRRX1;;chr20:30433396..30433414,-!p1@FOXS1!0.56!2.61!FOXS1;;chr12:53625966..53626012,-!p2@RARG!0.55!8.00!RARG;;chr2:200323414..200323455,-!p1@SATB2!0.55!6.33!SATB2;;chr5:43067636..43067674,+!p6@ZNF131!0.55!3.72!ZNF131;;chr11:46299186..46299195,+!p3@CREB3L1!0.55!2.98!CREB3L1;;chr12:124873357..124873401,-!p1@NCOR2!0.54!36.11!NCOR2;;chr3:128206762..128206781,-!p2@GATA2!0.54!18.98!GATA2;;chr10:63809077..63809089,+!p5@ARID5B!0.53!6.14!ARID5B;;chr12:48298765..48298783,-!p2@VDR!0.53!5.77!VDR;;chr16:54320646..54320672,-!p2@IRX3!0.53!4.09!IRX3;;chr17:46682321..46682362,-!p1@HOXB6!0.53!2.42!HOXB6;;chr5:2751785..2751808,-!p2@IRX2!0.53!2.42!IRX2;;chr1:119530636..119530653,-!p2@TBX15!0.53!2.42!TBX15;;chr19:33865009..33865090,+!p3@CEBPG!0.52!3.35!CEBPG;;chr19:13106214..13106382,+!p1@NFIX!0.51!67.37!NFIX;;chr9:35732647..35732678,+!p2@CREB3!0.51!16.01!CREB3;;chr3:114343768..114343822,-!p1@ZBTB20!0.51!12.47!ZBTB20;;chr19:47922750..47922795,-!p1@MEIS3!0.51!4.09!MEIS3;;chr5:72743793..72743855,-!p4@FOXD1!0.51!2.79!FOXD1;;chr5:3595934..3595957,+!p2@IRX1!0.51!2.23!IRX1;;chr8:93115584..93115642,-!p5@RUNX1T1!0.51!2.23!RUNX1T1;;chr2:102091144..102091183,-!p2@RFX8!0.51!2.23!RFX8;;chr2:177001290..177001315,+!p1@HOXD3!0.51!2.23!HOXD3;;chr2:66662396..66662407,+!p4@MEIS1!0.51!2.23!MEIS1;;chr11:44331576..44331650,-!p1@ALX4!0.51!2.23!ALX4;;chr19:13135582..13135600,+!p3@NFIX!0.51!2.23!NFIX;;chr19:9609272..9609297,-!p1@ZNF560!0.51!2.23!ZNF560;;chr2:71127699..71127744,+!p1@VAX2!0.50!5.21!VAX2;;chr11:707063..707088,-!p4@DEAF1!0.50!2.98!DEAF1;;chr15: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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000057;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0002620;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002097;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002416 | |||
|ffid_belonging_in_development=CL:0000134 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 41: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520skin%2520normal%252c%2520donor1.CNhs11351.11553-120C5.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520skin%2520normal%252c%2520donor1.CNhs11351.11553-120C5.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520skin%2520normal%252c%2520donor1.CNhs11351.11553-120C5.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520skin%2520normal%252c%2520donor1.CNhs11351.11553-120C5.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520skin%2520normal%252c%2520donor1.CNhs11351.11553-120C5.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11553-120C5 | |||
|is_a=EFO:0002091;;FF:0000250 | |||
|is_obsolete= | |||
|library_id=CNhs11351 | |||
|library_id_phase_based=2:CNhs11351 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11553 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11553 | |||
|name=Fibroblast - skin normal, donor1 | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs11351,LSID769,release014,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0.0687140423748555,0,0,0,0,0.165341513202496,0,-0.173963996100398,-0.282403560576942,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0791955324837987,0,0.096332581948584,0,0,0,-0.0979578962680575,0,0,-0.132956589778862,0,0,0,0,0,0,0,0,0,0,0.074127477864629,0,-0.0343672749680754,0,0,0,0,0,0,0,0,0.0128487178194801,0,0,0,0.074127477864629,0,0.0171016605409606,0,-0.0969923612426051,0,0,-0.097343627213097,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0522210343405287,0.0370637389323145,0,0,0,0,0,0,0,0,0,-0.0604553605811464,-0.031289280788703,0.0370637389323145,0.074127477864629,0,0.241662864220876,-0.0980353512377064,-0.138477200800895,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.168961867334621,0,0,0,-0.0485707522809905,-0.05166951246517,0,0,-0.0406607636248659,0,0,0 | |||
|repeat_enrich_byname=0,0,0,0,-0.0980353512377064,0,0.241662864220876,0,0,0.074127477864629,0,0,0,0.074127477864629,0,0,0.115080739106981,0.123843779363214,-0.148426675463126,-0.143515142523472,0,0,0.0705529541689772,0,0.137428084749711,0,0.0213130318792847,0.074127477864629,0,0.074127477864629,0,0,0.491389451879814,0,0.0237149262753141,0,0,0,0,0,0.12185995016573,0,0.13549659826668,0.327669267764119,0,0,0,0,0.17156427452131,0,-0.0467520059291117,0.242939374965465,0.234931856546729,0.101238112547896,0.018414981083447,0,0,0,0.0584399417127011,-0.00529539902222265,0,0,0.359857622022751,0.0166571458600847,0,0,1.29098820165596,0,-0.09536933565742,0.372624465521766,0,-0.0834008784991798,0,0,0,0,0,0,0,0,0,0,0,0.0388391151271475,-0.189560511929258,0.0284921187122163,0,0,0,0.00766667625739759,0.074127477864629,0,-0.235858071206856,0.157700204579276,-0.056329160260913,-0.324544627331192,0,-0.302389727009913,-0.0032008660705729,0.0771363583321402,-0.125800361165021,0.214857765021407,0.0516811446710288,0,0.0876680695778747,-0.0635821454120487,-0.0409434195949175,-0.105492749223293,-0.0088408609639373,-0.0730335407832818,-0.0535724387380896,0,0,0.115156237417865,0.151760404239304,0,-0.00795564299829499,0.385761676402033,-0.0415334555398524,0.239075448451651,0.082484443024275,0.0564359337545708,0.094215453266335,-0.00246878952435605,0.233508270917505,0,0.197495677731977,0,0,-0.0131756322475722,-0.0609944863807015,0.0790717602242038,-0.253566558786134,0,-0.198288695861278,0.1243209028198,0.0370637389323145,-0.0948614652946004,-0.0951837420104935,0,0.0377305401147581,0.158956316493093,0,0,0,0,0.074127477864629,-0.164332586312337,-0.00552710506385046,-0.232855561555545,0,-0.050111361271192,0.033664685449186,-0.083619989820518,0,-0.187250538480365,0.179649645831488,-0.00308073881992899,-0.155205719846525,0,-0.00418720876409295,0.0965186774682256,-0.0158087821802253,-0.136706039442035,-0.0584468268118252,-0.0563149457366232,-0.0888713329179475,-0.0604553605811464,0.363785514633192,0.0493811962795464,0.754216470279173,-0.0162286939682301,0.379116734503601,-0.393809365671822,0,-0.051833358902878,0.074127477864629,0.167742766195446,0,-0.151817659404986,0,-0.346001092700555,-0.0307740117952945,-0.365161896716057,-0.0175189945751613,0,-0.137482072669361,0.532316623975357,0,-0.0123483333996206,0.0232483251911555,0,0.211892531057906,-0.140714086639715,-9.20025148826997e-05,0.100187508244241,0,0.21508859368294,0,0,0.18390817360872,0.00618682645648744,0.074127477864629,0.0531233929296669,-0.0522210343405287,-0.120302907493572,-0.0418435955703051,0,0,0.0614072674299705,0,0.362259614392546,-0.46849997906832,0.222083920811901,-0.0409433026666092,-0.0606611775895873,0,0.183270799317031,0,0,0.18473184842737,0,0.157433692181129,0,0,-0.116484975717925,0,0,0,0.074127477864629,0,0.0523557292792288,0,0,0,0,0,0.0269358496123571,-0.029859892101761,-0.16216816631928,0,-0.0413796436490613,0,0.074127477864629,0,0,0.137428084749711,0,0,0.556981879872868,0.936898933594137,-0.00400073499986209,-0.0488899378117913,0,0,0,0,-0.0230582386563062,-0.129109084230095,0,0.00556537825207909,0,0.0370637389323145,0,0,-0.0861409897892114,0,0,0,0,0.134934706843504,0.0335349973266983,0,0,0,-0.27695440160179,0,0,0,0.00277165158531594,-0.0455125855714702,0,0.074127477864629,0.385563988508415,0,0.0134869167845335,-0.0815818795468414,0,0.064646586285593,0.411058580717028,0.0852331849981662,0,0,-0.261347131789888,0,0.0370637389323145,0.0288378002601941,0.02713369223677,0,-0.0102964334784856,0,0,0,0,0,0,-0.0768864276500448,0.0370637389323145,0,0.00809944313784405,0,0,0,0,0,0.074127477864629,0,0,0.126953040439006,0.0452040280912004,0,0,0,0,0,0,0,-0.0241060230789031,-0.250496045488876,0,0,0,0,0,0,0,0,0.0124871940384801,0,0,0,0,0,-0.0969923612426051,0,0,0,0.137428084749711,-0.564807121153884,0,0,-0.203234654328885,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0491916081708188,-0.173963996100398,0,0,0,0,0,0,0,-0.13740521345638,0,0,0,0,-0.0397568958443482,0,0,0,0.13686647943172,0,0.165341513202496,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0370637389323145,0,0,0,0.570917198448722,0.068667902494136,0.189581929844585,0.00410054215264766,0,0,0.182653874572307,0,0,0,0,0,0,0.00572331490378745,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0687140423748555,0.00220569512722611,0,0,0,0,0.074127477864629,0,0,-0.0979578962680575,0,0,-0.0233187674256707,0,0,0,0,0,0,0.266678305840067,0.493407069233183,0.00659256198096165,0,0,0,0.108444199161986,0.074127477864629,0,0,0,0.490204492453966,0,0,0,0,0,0,0,0,0.074127477864629,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0791955324837987,0,0,0,0,0,0,0,0,0,0,0,0,0.096332581948584,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.074127477864629,0,0,0,0,0,0,0,-0.0340113632754165,0.074127477864629,0,0,0,0,0,0,0.074127477864629,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0800184682686384,0,0,0,-0.213086229657044,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.074127477864629,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.331301389085766,0,0,0,0,0,0,0,0,0.074127477864629,0,0,0,0,-0.0482220752390542,0,-0.084376632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| |||
|rna_box=120 | |||
|rna_catalog_number=custom | |||
|rna_concentration=0.984 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-TRIzol-ethanol-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=2.04 | |||
|rna_od260/280=2.11 | |||
|rna_position=C5 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=120C5 | |||
|rna_weight_ug=132.7752 | |||
|sample_age=25 year old | |||
|sample_category=primary cells | |||
|sample_cell_catalog=N/A | |||
|sample_cell_line= | |||
|sample_cell_lot=GM03440 | |||
|sample_cell_type=fibroblast | |||
|sample_collaboration=Splicing (contact: Al Forrest) | |||
|sample_company=Coriell | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=APPARENTLY HEALTHY NON-FETAL T | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=C | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;5.67934034305498e-210!GO:0005737;cytoplasm;1.09102205224461e-182!GO:0043226;organelle;1.95534422204121e-161!GO:0043229;intracellular organelle;4.67313372346398e-161!GO:0043231;intracellular membrane-bound organelle;3.59229897146695e-157!GO:0043227;membrane-bound organelle;5.84607569957804e-157!GO:0044444;cytoplasmic part;1.26539112102963e-133!GO:0044422;organelle part;8.38366397799684e-116!GO:0044446;intracellular organelle part;2.34240391505596e-114!GO:0032991;macromolecular complex;1.96230142827113e-81!GO:0005515;protein binding;7.21354509769088e-76!GO:0030529;ribonucleoprotein complex;2.24664852706514e-74!GO:0044238;primary metabolic process;8.95992114983763e-73!GO:0044237;cellular metabolic process;1.51401194375332e-72!GO:0043170;macromolecule metabolic process;3.29955066468473e-69!GO:0043233;organelle lumen;1.05861645606392e-60!GO:0031974;membrane-enclosed lumen;1.05861645606392e-60!GO:0003723;RNA binding;2.72840002321903e-57!GO:0005739;mitochondrion;3.37692143170819e-57!GO:0044428;nuclear part;6.32580522993408e-55!GO:0005634;nucleus;7.26329126521055e-52!GO:0019538;protein metabolic process;1.31517170090934e-48!GO:0031090;organelle membrane;8.24374209761561e-48!GO:0005840;ribosome;2.16089246723643e-46!GO:0015031;protein transport;5.0799838168385e-45!GO:0016043;cellular component organization and biogenesis;6.18429800892255e-45!GO:0006412;translation;7.41201418973264e-45!GO:0033036;macromolecule localization;7.97312421617533e-45!GO:0044260;cellular macromolecule metabolic process;2.37054541772699e-43!GO:0044267;cellular protein metabolic process;3.26198862370638e-42!GO:0008104;protein localization;9.1775444215867e-42!GO:0045184;establishment of protein localization;1.13011605677432e-41!GO:0003735;structural constituent of ribosome;5.89078967363359e-41!GO:0043234;protein complex;3.13350183483124e-40!GO:0044429;mitochondrial part;2.33003864270337e-38!GO:0006396;RNA processing;1.07523721494127e-37!GO:0009058;biosynthetic process;5.43187463578555e-37!GO:0005829;cytosol;8.84175553413585e-37!GO:0009059;macromolecule biosynthetic process;3.28411628473144e-36!GO:0033279;ribosomal subunit;2.11530351702426e-35!GO:0031981;nuclear lumen;1.28880517531445e-34!GO:0046907;intracellular transport;1.8771794716574e-34!GO:0044249;cellular biosynthetic process;3.58327592277521e-34!GO:0043283;biopolymer metabolic process;5.16716568145059e-34!GO:0031967;organelle envelope;1.21262576058723e-33!GO:0031975;envelope;2.14203718877131e-33!GO:0010467;gene expression;3.75688461478106e-33!GO:0016071;mRNA metabolic process;2.31790134925074e-32!GO:0008380;RNA splicing;9.18611436999478e-30!GO:0006886;intracellular protein transport;2.91355996892759e-29!GO:0006397;mRNA processing;1.14983110955548e-27!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;5.11561009477007e-27!GO:0065003;macromolecular complex assembly;1.68632233325382e-26!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.88663640167889e-26!GO:0022613;ribonucleoprotein complex biogenesis and assembly;2.37183889589907e-25!GO:0005740;mitochondrial envelope;5.30091715054191e-25!GO:0022607;cellular component assembly;6.31300978770881e-24!GO:0031966;mitochondrial membrane;1.04670727146059e-23!GO:0006996;organelle organization and biogenesis;1.61794943830371e-23!GO:0019866;organelle inner membrane;2.54087055085477e-23!GO:0005654;nucleoplasm;2.89798949831254e-22!GO:0005743;mitochondrial inner membrane;4.01010341106849e-22!GO:0043228;non-membrane-bound organelle;4.14390198745804e-22!GO:0043232;intracellular non-membrane-bound organelle;4.14390198745804e-22!GO:0005783;endoplasmic reticulum;7.03095674320072e-22!GO:0051649;establishment of cellular localization;1.32998122035726e-21!GO:0051641;cellular localization;2.55253547098698e-21!GO:0005681;spliceosome;4.27100347903203e-21!GO:0006119;oxidative phosphorylation;9.4047443768937e-21!GO:0006457;protein folding;1.89672522915499e-20!GO:0044445;cytosolic part;2.84252409144253e-20!GO:0012505;endomembrane system;1.12118431317468e-19!GO:0048770;pigment granule;2.40287212287645e-19!GO:0042470;melanosome;2.40287212287645e-19!GO:0015934;large ribosomal subunit;2.7694298320989e-18!GO:0044455;mitochondrial membrane part;3.84132100092022e-18!GO:0044451;nucleoplasm part;4.27678882832506e-18!GO:0015935;small ribosomal subunit;4.60089304618496e-18!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;8.05599588774604e-18!GO:0016462;pyrophosphatase activity;8.36391854544668e-18!GO:0005794;Golgi apparatus;9.52440651778899e-18!GO:0016817;hydrolase activity, acting on acid anhydrides;1.22033838122329e-17!GO:0017111;nucleoside-triphosphatase activity;3.139915288856e-17!GO:0044432;endoplasmic reticulum part;3.43756945010121e-17!GO:0022618;protein-RNA complex assembly;3.91099684495568e-17!GO:0048193;Golgi vesicle transport;1.79003029280925e-16!GO:0000166;nucleotide binding;2.43681737452724e-16!GO:0031980;mitochondrial lumen;3.80756909309657e-16!GO:0005759;mitochondrial matrix;3.80756909309657e-16!GO:0016874;ligase activity;5.20684717191725e-16!GO:0006512;ubiquitin cycle;8.09393692992234e-16!GO:0051603;proteolysis involved in cellular protein catabolic process;1.84445758117106e-15!GO:0005746;mitochondrial respiratory chain;2.34218198532038e-15!GO:0043285;biopolymer catabolic process;2.50047796664667e-15!GO:0008135;translation factor activity, nucleic acid binding;2.7625875667983e-15!GO:0000502;proteasome complex (sensu Eukaryota);3.22233789740143e-15!GO:0003676;nucleic acid binding;3.53685515741029e-15!GO:0019941;modification-dependent protein catabolic process;3.97109656781857e-15!GO:0043632;modification-dependent macromolecule catabolic process;3.97109656781857e-15!GO:0044257;cellular protein catabolic process;5.19678497419433e-15!GO:0008134;transcription factor binding;5.41690077881982e-15!GO:0006511;ubiquitin-dependent protein catabolic process;6.08692251570644e-15!GO:0044265;cellular macromolecule catabolic process;7.59033518187111e-15!GO:0016192;vesicle-mediated transport;8.79210638568317e-15!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;1.1557054747227e-14!GO:0051186;cofactor metabolic process;1.71913394397226e-14!GO:0006259;DNA metabolic process;2.2241041320494e-14!GO:0051082;unfolded protein binding;2.77405396579654e-14!GO:0006605;protein targeting;3.68568755026329e-14!GO:0030163;protein catabolic process;4.70729129838983e-14!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.082730562362e-13!GO:0009057;macromolecule catabolic process;1.13801119392062e-13!GO:0050136;NADH dehydrogenase (quinone) activity;1.19017189925815e-13!GO:0003954;NADH dehydrogenase activity;1.19017189925815e-13!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.19017189925815e-13!GO:0016070;RNA metabolic process;2.48846682726547e-13!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);4.10592582958865e-13!GO:0005761;mitochondrial ribosome;4.7904296318787e-13!GO:0000313;organellar ribosome;4.7904296318787e-13!GO:0005730;nucleolus;5.27485792626104e-13!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;5.96004753261485e-13!GO:0005793;ER-Golgi intermediate compartment;3.65827271443125e-12!GO:0042775;organelle ATP synthesis coupled electron transport;4.32873776120098e-12!GO:0042773;ATP synthesis coupled electron transport;4.32873776120098e-12!GO:0044248;cellular catabolic process;4.9730938895122e-12!GO:0003743;translation initiation factor activity;5.74972013925185e-12!GO:0030964;NADH dehydrogenase complex (quinone);5.78095536844846e-12!GO:0045271;respiratory chain complex I;5.78095536844846e-12!GO:0005747;mitochondrial respiratory chain complex I;5.78095536844846e-12!GO:0042175;nuclear envelope-endoplasmic reticulum network;7.25303750183841e-12!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;1.5359623835001e-11!GO:0006413;translational initiation;2.03441164309819e-11!GO:0005789;endoplasmic reticulum membrane;2.45274406760616e-11!GO:0009055;electron carrier activity;2.57293215199225e-11!GO:0032553;ribonucleotide binding;3.04226409456962e-11!GO:0032555;purine ribonucleotide binding;3.04226409456962e-11!GO:0017076;purine nucleotide binding;3.05520099673484e-11!GO:0000398;nuclear mRNA splicing, via spliceosome;3.13376003555493e-11!GO:0000375;RNA splicing, via transesterification reactions;3.13376003555493e-11!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;3.13376003555493e-11!GO:0006732;coenzyme metabolic process;4.8095130017121e-11!GO:0043412;biopolymer modification;4.91208504079104e-11!GO:0003712;transcription cofactor activity;1.95734967014047e-10!GO:0006446;regulation of translational initiation;3.62793096212806e-10!GO:0006464;protein modification process;3.99870811922202e-10!GO:0007049;cell cycle;4.24030116349892e-10!GO:0012501;programmed cell death;5.78836402150534e-10!GO:0008639;small protein conjugating enzyme activity;9.48794159895911e-10!GO:0019787;small conjugating protein ligase activity;1.23946876046351e-09!GO:0006915;apoptosis;1.52978500907022e-09!GO:0004842;ubiquitin-protein ligase activity;1.65691372635916e-09!GO:0009259;ribonucleotide metabolic process;1.80111945266835e-09!GO:0005635;nuclear envelope;1.99739357450359e-09!GO:0042254;ribosome biogenesis and assembly;3.73531973704658e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;3.73531973704658e-09!GO:0008219;cell death;4.08609060587797e-09!GO:0016265;death;4.08609060587797e-09!GO:0031965;nuclear membrane;4.11974591282064e-09!GO:0008565;protein transporter activity;4.4227488580242e-09!GO:0006913;nucleocytoplasmic transport;4.67293466110995e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;4.92726427984568e-09!GO:0006888;ER to Golgi vesicle-mediated transport;4.92726427984568e-09!GO:0006163;purine nucleotide metabolic process;5.16809516535423e-09!GO:0006974;response to DNA damage stimulus;5.16809516535423e-09!GO:0009150;purine ribonucleotide metabolic process;5.76057996953653e-09!GO:0051169;nuclear transport;9.04413591135238e-09!GO:0048523;negative regulation of cellular process;1.15822567848596e-08!GO:0003924;GTPase activity;1.15822567848596e-08!GO:0006461;protein complex assembly;1.33049092861834e-08!GO:0016604;nuclear body;1.41057214011719e-08!GO:0005788;endoplasmic reticulum lumen;1.42144840345992e-08!GO:0006164;purine nucleotide biosynthetic process;1.67847354071446e-08!GO:0030120;vesicle coat;1.71100286460562e-08!GO:0030662;coated vesicle membrane;1.71100286460562e-08!GO:0043687;post-translational protein modification;1.72075765852703e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;1.74372547200912e-08!GO:0009152;purine ribonucleotide biosynthetic process;1.75908366191265e-08!GO:0009260;ribonucleotide biosynthetic process;1.82891623267814e-08!GO:0009199;ribonucleoside triphosphate metabolic process;1.98441388109137e-08!GO:0016881;acid-amino acid ligase activity;2.6104124877962e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;2.6604289035482e-08!GO:0009144;purine nucleoside triphosphate metabolic process;2.6604289035482e-08!GO:0042623;ATPase activity, coupled;2.77047980689482e-08!GO:0009060;aerobic respiration;2.97071160377228e-08!GO:0005524;ATP binding;3.02626580775975e-08!GO:0009141;nucleoside triphosphate metabolic process;3.72526585760835e-08!GO:0016887;ATPase activity;3.76442516999411e-08!GO:0045333;cellular respiration;4.03350238898313e-08!GO:0032559;adenyl ribonucleotide binding;4.36076984173926e-08!GO:0005768;endosome;4.78551156464781e-08!GO:0044453;nuclear membrane part;4.994130361404e-08!GO:0030554;adenyl nucleotide binding;5.52784886802925e-08!GO:0015986;ATP synthesis coupled proton transport;5.86480969732202e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;5.86480969732202e-08!GO:0044431;Golgi apparatus part;9.58347391257825e-08!GO:0050794;regulation of cellular process;1.0826579454458e-07!GO:0048475;coated membrane;1.23900047037236e-07!GO:0030117;membrane coat;1.23900047037236e-07!GO:0009142;nucleoside triphosphate biosynthetic process;1.26437919033488e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.26437919033488e-07!GO:0006366;transcription from RNA polymerase II promoter;1.65051547685593e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;1.66598653184707e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;1.66598653184707e-07!GO:0046034;ATP metabolic process;1.78171507665317e-07!GO:0017038;protein import;1.84773537118407e-07!GO:0009056;catabolic process;1.97965785936813e-07!GO:0051246;regulation of protein metabolic process;2.40489790556409e-07!GO:0008026;ATP-dependent helicase activity;2.45082582215675e-07!GO:0006399;tRNA metabolic process;2.58844943653357e-07!GO:0051187;cofactor catabolic process;2.68605223109809e-07!GO:0019829;cation-transporting ATPase activity;2.77336275075748e-07!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;2.82273893233436e-07!GO:0016607;nuclear speck;2.84429342477762e-07!GO:0022402;cell cycle process;2.90382009517726e-07!GO:0004386;helicase activity;3.02027554807609e-07!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;3.0804716008272e-07!GO:0004812;aminoacyl-tRNA ligase activity;3.0804716008272e-07!GO:0016875;ligase activity, forming carbon-oxygen bonds;3.0804716008272e-07!GO:0048519;negative regulation of biological process;3.61565984077341e-07!GO:0065002;intracellular protein transport across a membrane;3.66642643956864e-07!GO:0006099;tricarboxylic acid cycle;3.81030434032449e-07!GO:0046356;acetyl-CoA catabolic process;3.81030434032449e-07!GO:0015078;hydrogen ion transmembrane transporter activity;4.2125674386833e-07!GO:0043038;amino acid activation;4.46114803652511e-07!GO:0006418;tRNA aminoacylation for protein translation;4.46114803652511e-07!GO:0043039;tRNA aminoacylation;4.46114803652511e-07!GO:0009109;coenzyme catabolic process;5.21629045841209e-07!GO:0016491;oxidoreductase activity;5.30980859538453e-07!GO:0006281;DNA repair;5.65493553215115e-07!GO:0009719;response to endogenous stimulus;7.55720976850104e-07!GO:0051188;cofactor biosynthetic process;8.99449166898824e-07!GO:0006754;ATP biosynthetic process;9.67598610227938e-07!GO:0006753;nucleoside phosphate metabolic process;9.67598610227938e-07!GO:0005839;proteasome core complex (sensu Eukaryota);1.13027730153897e-06!GO:0016023;cytoplasmic membrane-bound vesicle;1.41642949737363e-06!GO:0031988;membrane-bound vesicle;1.42752081031485e-06!GO:0016469;proton-transporting two-sector ATPase complex;1.657159498915e-06!GO:0043069;negative regulation of programmed cell death;1.71902084982984e-06!GO:0006084;acetyl-CoA metabolic process;1.85324839226278e-06!GO:0005798;Golgi-associated vesicle;2.052665013925e-06!GO:0005773;vacuole;2.06532345402318e-06!GO:0000278;mitotic cell cycle;2.26888374783365e-06!GO:0030036;actin cytoskeleton organization and biogenesis;2.29593306427554e-06!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;2.3239888091777e-06!GO:0051789;response to protein stimulus;2.42610450890651e-06!GO:0006986;response to unfolded protein;2.42610450890651e-06!GO:0006916;anti-apoptosis;2.57813672729279e-06!GO:0043067;regulation of programmed cell death;2.6263704085213e-06!GO:0005643;nuclear pore;2.86761251885694e-06!GO:0030532;small nuclear ribonucleoprotein complex;3.00551146043437e-06!GO:0003714;transcription corepressor activity;3.23278866895967e-06!GO:0044440;endosomal part;3.27796906116711e-06!GO:0010008;endosome membrane;3.27796906116711e-06!GO:0000151;ubiquitin ligase complex;3.39065339841567e-06!GO:0042981;regulation of apoptosis;3.61793908586386e-06!GO:0043066;negative regulation of apoptosis;4.04673302021804e-06!GO:0032446;protein modification by small protein conjugation;4.28404471918938e-06!GO:0009117;nucleotide metabolic process;4.49730455641098e-06!GO:0031982;vesicle;5.88760673007873e-06!GO:0006325;establishment and/or maintenance of chromatin architecture;6.2346103525369e-06!GO:0045259;proton-transporting ATP synthase complex;6.2666867068969e-06!GO:0004298;threonine endopeptidase activity;6.42382986466594e-06!GO:0031252;leading edge;6.42382986466594e-06!GO:0007005;mitochondrion organization and biogenesis;6.63588799993237e-06!GO:0016567;protein ubiquitination;6.64822393545243e-06!GO:0005667;transcription factor complex;6.88970076374583e-06!GO:0008361;regulation of cell size;6.90626660725479e-06!GO:0031410;cytoplasmic vesicle;7.11449622633201e-06!GO:0000139;Golgi membrane;7.3375890525084e-06!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;7.56706905306904e-06!GO:0051726;regulation of cell cycle;7.61119122589536e-06!GO:0005525;GTP binding;8.17844165432628e-06!GO:0000074;regulation of progression through cell cycle;8.55176115864943e-06!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;8.61740399619148e-06!GO:0016049;cell growth;9.17494039290047e-06!GO:0015980;energy derivation by oxidation of organic compounds;1.02412451523738e-05!GO:0050657;nucleic acid transport;1.06348632719784e-05!GO:0051236;establishment of RNA localization;1.06348632719784e-05!GO:0050658;RNA transport;1.06348632719784e-05!GO:0006403;RNA localization;1.13568568966362e-05!GO:0006613;cotranslational protein targeting to membrane;1.13787535135371e-05!GO:0006364;rRNA processing;1.33977529461121e-05!GO:0006752;group transfer coenzyme metabolic process;1.35030392011576e-05!GO:0015077;monovalent inorganic cation transmembrane transporter activity;1.47359565575713e-05!GO:0006323;DNA packaging;1.47427467595625e-05!GO:0008654;phospholipid biosynthetic process;1.47587134137838e-05!GO:0050789;regulation of biological process;1.50063549816293e-05!GO:0003697;single-stranded DNA binding;1.64255079506528e-05!GO:0000323;lytic vacuole;1.75133739174451e-05!GO:0005764;lysosome;1.75133739174451e-05!GO:0000245;spliceosome assembly;1.90270007621528e-05!GO:0046930;pore complex;2.10613476164167e-05!GO:0016787;hydrolase activity;2.22088238402052e-05!GO:0016072;rRNA metabolic process;2.28661703034817e-05!GO:0030029;actin filament-based process;2.3699421351568e-05!GO:0031324;negative regulation of cellular metabolic process;2.50611498861653e-05!GO:0006091;generation of precursor metabolites and energy;2.68933804330001e-05!GO:0051276;chromosome organization and biogenesis;2.95357143841698e-05!GO:0009108;coenzyme biosynthetic process;2.95357143841698e-05!GO:0016564;transcription repressor activity;3.02683275688918e-05!GO:0030133;transport vesicle;3.16690202470428e-05!GO:0051170;nuclear import;3.20563677724286e-05!GO:0030867;rough endoplasmic reticulum membrane;4.10423960457535e-05!GO:0032561;guanyl ribonucleotide binding;4.62881856741447e-05!GO:0019001;guanyl nucleotide binding;4.62881856741447e-05!GO:0003724;RNA helicase activity;4.95403530608812e-05!GO:0001558;regulation of cell growth;5.08077514039132e-05!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;5.12959197189851e-05!GO:0005762;mitochondrial large ribosomal subunit;5.19484862892257e-05!GO:0000315;organellar large ribosomal subunit;5.19484862892257e-05!GO:0006606;protein import into nucleus;5.20959654313746e-05!GO:0016853;isomerase activity;5.40693658377711e-05!GO:0031202;RNA splicing factor activity, transesterification mechanism;5.99073733455033e-05!GO:0045454;cell redox homeostasis;5.99111788100374e-05!GO:0019843;rRNA binding;6.39873852651704e-05!GO:0005769;early endosome;6.50218761503045e-05!GO:0043566;structure-specific DNA binding;6.90910139438e-05!GO:0007249;I-kappaB kinase/NF-kappaB cascade;6.99452496962275e-05!GO:0005770;late endosome;7.31928704962041e-05!GO:0016859;cis-trans isomerase activity;7.58652337272297e-05!GO:0065004;protein-DNA complex assembly;8.47704157021701e-05!GO:0033116;ER-Golgi intermediate compartment membrane;8.9300191798311e-05!GO:0003713;transcription coactivator activity;8.9300191798311e-05!GO:0045786;negative regulation of progression through cell cycle;9.9243285116713e-05!GO:0043021;ribonucleoprotein binding;0.000129989774560045!GO:0009892;negative regulation of metabolic process;0.000132768177846268!GO:0008092;cytoskeletal protein binding;0.000147450012618288!GO:0005905;coated pit;0.000155931668431033!GO:0030663;COPI coated vesicle membrane;0.000162446044364545!GO:0030126;COPI vesicle coat;0.000162446044364545!GO:0016568;chromatin modification;0.000165601436373899!GO:0005791;rough endoplasmic reticulum;0.000187892163759106!GO:0043623;cellular protein complex assembly;0.000194889825318602!GO:0007010;cytoskeleton organization and biogenesis;0.000198113777770851!GO:0006612;protein targeting to membrane;0.000205981691218317!GO:0051028;mRNA transport;0.000217560510890736!GO:0015630;microtubule cytoskeleton;0.000219460693546117!GO:0005048;signal sequence binding;0.000223531720791806!GO:0006793;phosphorus metabolic process;0.000252023142479783!GO:0006796;phosphate metabolic process;0.000252023142479783!GO:0008250;oligosaccharyl transferase complex;0.000272116441334702!GO:0006260;DNA replication;0.000292385505273062!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;0.000303422167307277!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000304292186054412!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.000313097913738101!GO:0046474;glycerophospholipid biosynthetic process;0.000319983975489377!GO:0005885;Arp2/3 protein complex;0.00033350309906741!GO:0016563;transcription activator activity;0.000348819730400423!GO:0030137;COPI-coated vesicle;0.000368978086278372!GO:0004576;oligosaccharyl transferase activity;0.000372097719885798!GO:0019899;enzyme binding;0.000382748687048703!GO:0006891;intra-Golgi vesicle-mediated transport;0.000401950119180463!GO:0007264;small GTPase mediated signal transduction;0.000409934706332289!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.000422214780608997!GO:0005813;centrosome;0.000471399394061698!GO:0031968;organelle outer membrane;0.000568704827165305!GO:0019867;outer membrane;0.000640188043508921!GO:0048522;positive regulation of cellular process;0.00064038103100698!GO:0000314;organellar small ribosomal subunit;0.000642662879880214!GO:0005763;mitochondrial small ribosomal subunit;0.000642662879880214!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00065972932896579!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000690365992514361!GO:0016740;transferase activity;0.000778634367326415!GO:0016310;phosphorylation;0.00078330958954097!GO:0044262;cellular carbohydrate metabolic process;0.000822314333693124!GO:0051920;peroxiredoxin activity;0.00083119313643866!GO:0016481;negative regulation of transcription;0.000857864410754083!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000873339982427615!GO:0004177;aminopeptidase activity;0.000914996025187761!GO:0019222;regulation of metabolic process;0.000921759730613398!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000954611840457891!GO:0000087;M phase of mitotic cell cycle;0.000961072799172275!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.000984708457711801!GO:0008186;RNA-dependent ATPase activity;0.00102593094678698!GO:0016779;nucleotidyltransferase activity;0.00106360210332892!GO:0043284;biopolymer biosynthetic process;0.00107719821350537!GO:0007067;mitosis;0.00107881550123498!GO:0005815;microtubule organizing center;0.00110114062239567!GO:0006333;chromatin assembly or disassembly;0.00110262336816114!GO:0007243;protein kinase cascade;0.00112991823907955!GO:0005694;chromosome;0.00113914549312295!GO:0018196;peptidyl-asparagine modification;0.00117102256870784!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00117102256870784!GO:0008047;enzyme activator activity;0.00119553001076106!GO:0016197;endosome transport;0.00120737511008376!GO:0051427;hormone receptor binding;0.00134124382201737!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.0013637525637644!GO:0022403;cell cycle phase;0.00141329663362994!GO:0051168;nuclear export;0.00142203818136221!GO:0030658;transport vesicle membrane;0.00142700823369956!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00143163044378228!GO:0046489;phosphoinositide biosynthetic process;0.00155174497597268!GO:0006414;translational elongation;0.00163834716556897!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.0018149504454796!GO:0015399;primary active transmembrane transporter activity;0.0018149504454796!GO:0051252;regulation of RNA metabolic process;0.00199108166052348!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00199182506880997!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00199182506880997!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00199182506880997!GO:0005741;mitochondrial outer membrane;0.00225261927558961!GO:0003729;mRNA binding;0.00225261927558961!GO:0048500;signal recognition particle;0.00231789115456031!GO:0035257;nuclear hormone receptor binding;0.00241330888982846!GO:0040008;regulation of growth;0.00243236965813817!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00250157806985315!GO:0043681;protein import into mitochondrion;0.00250964369427503!GO:0051301;cell division;0.00259303475695522!GO:0030134;ER to Golgi transport vesicle;0.00259539677724714!GO:0004004;ATP-dependent RNA helicase activity;0.00262790531148071!GO:0045045;secretory pathway;0.00282340037365561!GO:0030132;clathrin coat of coated pit;0.00284234708907375!GO:0048471;perinuclear region of cytoplasm;0.00286085920015317!GO:0003899;DNA-directed RNA polymerase activity;0.00287773289924364!GO:0016044;membrane organization and biogenesis;0.00293494030806894!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00304377172313262!GO:0003746;translation elongation factor activity;0.00311163722489208!GO:0030027;lamellipodium;0.00326503454019501!GO:0046483;heterocycle metabolic process;0.00334307679623416!GO:0046467;membrane lipid biosynthetic process;0.00356332370852205!GO:0009165;nucleotide biosynthetic process;0.00377831691809276!GO:0030127;COPII vesicle coat;0.00382975274617092!GO:0012507;ER to Golgi transport vesicle membrane;0.00382975274617092!GO:0031072;heat shock protein binding;0.00387999989205041!GO:0006626;protein targeting to mitochondrion;0.00387999989205041!GO:0030041;actin filament polymerization;0.00399731629763094!GO:0044427;chromosomal part;0.00408040942327617!GO:0006650;glycerophospholipid metabolic process;0.00412642930200207!GO:0006354;RNA elongation;0.00428017679865066!GO:0007050;cell cycle arrest;0.00441143816615557!GO:0016363;nuclear matrix;0.00445291029115076!GO:0030660;Golgi-associated vesicle membrane;0.00455423427608093!GO:0043488;regulation of mRNA stability;0.00457580723619062!GO:0043487;regulation of RNA stability;0.00457580723619062!GO:0006892;post-Golgi vesicle-mediated transport;0.00477646546350328!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0050347159136659!GO:0045047;protein targeting to ER;0.0050347159136659!GO:0000785;chromatin;0.00509327209041972!GO:0008154;actin polymerization and/or depolymerization;0.00511614135802788!GO:0051329;interphase of mitotic cell cycle;0.00515745911042475!GO:0030176;integral to endoplasmic reticulum membrane;0.005330902396072!GO:0008180;signalosome;0.00534273779748429!GO:0006402;mRNA catabolic process;0.00553541073094857!GO:0005869;dynactin complex;0.00566151381711797!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00577396915632515!GO:0030118;clathrin coat;0.00604991187015649!GO:0017166;vinculin binding;0.00630034750366328!GO:0030521;androgen receptor signaling pathway;0.00645083299750152!GO:0043433;negative regulation of transcription factor activity;0.00645083299750152!GO:0051128;regulation of cellular component organization and biogenesis;0.00651878267085384!GO:0016772;transferase activity, transferring phosphorus-containing groups;0.00659526334425653!GO:0006383;transcription from RNA polymerase III promoter;0.00667983510292279!GO:0065007;biological regulation;0.00674794816541124!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0068489321979482!GO:0048487;beta-tubulin binding;0.00685094674239678!GO:0003711;transcription elongation regulator activity;0.00685899096527358!GO:0031543;peptidyl-proline dioxygenase activity;0.00695473082041992!GO:0006509;membrane protein ectodomain proteolysis;0.00697006557616609!GO:0033619;membrane protein proteolysis;0.00697006557616609!GO:0007006;mitochondrial membrane organization and biogenesis;0.00734908125222189!GO:0006497;protein amino acid lipidation;0.00771363252153201!GO:0006740;NADPH regeneration;0.00777575666456528!GO:0006098;pentose-phosphate shunt;0.00777575666456528!GO:0001726;ruffle;0.00784562416458057!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.00790472244198488!GO:0051087;chaperone binding;0.00795351251453079!GO:0005581;collagen;0.00802126233274117!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00825128474785798!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00825128474785798!GO:0044420;extracellular matrix part;0.0085805045668194!GO:0048468;cell development;0.00859863986142791!GO:0008312;7S RNA binding;0.00882655201073368!GO:0006839;mitochondrial transport;0.00888783655513942!GO:0030880;RNA polymerase complex;0.00888783655513942!GO:0019798;procollagen-proline dioxygenase activity;0.0093873466859326!GO:0022890;inorganic cation transmembrane transporter activity;0.00978736580217903!GO:0051325;interphase;0.00981038937232101!GO:0006289;nucleotide-excision repair;0.00995057868109776!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.00996799996034303!GO:0031901;early endosome membrane;0.0100862820626305!GO:0030833;regulation of actin filament polymerization;0.0102852073203265!GO:0007265;Ras protein signal transduction;0.0102852073203265!GO:0006979;response to oxidative stress;0.010435169760516!GO:0065009;regulation of a molecular function;0.010435169760516!GO:0000049;tRNA binding;0.0105512189885251!GO:0005583;fibrillar collagen;0.0107263222477332!GO:0007034;vacuolar transport;0.0109548373523676!GO:0008022;protein C-terminus binding;0.0110014163995894!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0110014163995894!GO:0015002;heme-copper terminal oxidase activity;0.0110014163995894!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0110014163995894!GO:0004129;cytochrome-c oxidase activity;0.0110014163995894!GO:0006334;nucleosome assembly;0.011071229542938!GO:0051287;NAD binding;0.0114222084837351!GO:0003779;actin binding;0.0115966324886275!GO:0050811;GABA receptor binding;0.0117365486794573!GO:0005096;GTPase activator activity;0.0117909011198784!GO:0042802;identical protein binding;0.0118046510720036!GO:0001527;microfibril;0.012189329834212!GO:0005862;muscle thin filament tropomyosin;0.0123252644208528!GO:0008610;lipid biosynthetic process;0.0126432428357096!GO:0045792;negative regulation of cell size;0.0126432428357096!GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;0.0126432428357096!GO:0031418;L-ascorbic acid binding;0.012810433282294!GO:0000059;protein import into nucleus, docking;0.0128760140227443!GO:0006595;polyamine metabolic process;0.01293359069513!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0129762005551785!GO:0015992;proton transport;0.0129920555399581!GO:0015631;tubulin binding;0.0131376326848722!GO:0006352;transcription initiation;0.0132079616542267!GO:0043492;ATPase activity, coupled to movement of substances;0.0132472191775175!GO:0006506;GPI anchor biosynthetic process;0.0133122104878936!GO:0009112;nucleobase metabolic process;0.0133328966582318!GO:0030384;phosphoinositide metabolic process;0.0144383008583066!GO:0003684;damaged DNA binding;0.0145568163801061!GO:0003690;double-stranded DNA binding;0.0145568163801061!GO:0030865;cortical cytoskeleton organization and biogenesis;0.0145877809491294!GO:0007040;lysosome organization and biogenesis;0.0146315872399965!GO:0006401;RNA catabolic process;0.01496307144132!GO:0032984;macromolecular complex disassembly;0.0150664713638187!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.0150870922060548!GO:0030308;negative regulation of cell growth;0.015270066773394!GO:0000339;RNA cap binding;0.0153659318107499!GO:0006818;hydrogen transport;0.0153659318107499!GO:0008139;nuclear localization sequence binding;0.0153659318107499!GO:0032940;secretion by cell;0.0162416909541138!GO:0048518;positive regulation of biological process;0.0162520593509289!GO:0030659;cytoplasmic vesicle membrane;0.0164744793925783!GO:0043022;ribosome binding;0.0164744793925783!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.0164744793925783!GO:0000428;DNA-directed RNA polymerase complex;0.0164744793925783!GO:0005684;U2-dependent spliceosome;0.0165499719518718!GO:0031625;ubiquitin protein ligase binding;0.01733394553993!GO:0031497;chromatin assembly;0.017720425235743!GO:0042158;lipoprotein biosynthetic process;0.0181380580686959!GO:0035035;histone acetyltransferase binding;0.0183696730259383!GO:0006505;GPI anchor metabolic process;0.0186340142920871!GO:0009116;nucleoside metabolic process;0.0186984222118372!GO:0031124;mRNA 3'-end processing;0.0189367045665317!GO:0006984;ER-nuclear signaling pathway;0.0189968353946928!GO:0051493;regulation of cytoskeleton organization and biogenesis;0.0191924926989914!GO:0033043;regulation of organelle organization and biogenesis;0.0191924926989914!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0192596946148805!GO:0035258;steroid hormone receptor binding;0.019263996654415!GO:0000209;protein polyubiquitination;0.0193296606645591!GO:0016272;prefoldin complex;0.0193296606645591!GO:0043624;cellular protein complex disassembly;0.0193296606645591!GO:0007033;vacuole organization and biogenesis;0.0193296606645591!GO:0031529;ruffle organization and biogenesis;0.0193296606645591!GO:0006778;porphyrin metabolic process;0.0193296606645591!GO:0033013;tetrapyrrole metabolic process;0.0193296606645591!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.0196220349780105!GO:0050681;androgen receptor binding;0.0196944768688545!GO:0007021;tubulin folding;0.0197006852723725!GO:0045892;negative regulation of transcription, DNA-dependent;0.0197006852723725!GO:0009967;positive regulation of signal transduction;0.0199097664378452!GO:0030125;clathrin vesicle coat;0.0202845752497188!GO:0030665;clathrin coated vesicle membrane;0.0202845752497188!GO:0030032;lamellipodium biogenesis;0.0211549904728598!GO:0008064;regulation of actin polymerization and/or depolymerization;0.0217320619661749!GO:0016126;sterol biosynthetic process;0.0220547014918959!GO:0016251;general RNA polymerase II transcription factor activity;0.0220959725697051!GO:0007030;Golgi organization and biogenesis;0.0221269193959756!GO:0050662;coenzyme binding;0.0227540837930349!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0230714787482737!GO:0051540;metal cluster binding;0.023336346518346!GO:0051536;iron-sulfur cluster binding;0.023336346518346!GO:0005832;chaperonin-containing T-complex;0.0236434667012355!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0237169692786388!GO:0003923;GPI-anchor transamidase activity;0.0241169058792835!GO:0016255;attachment of GPI anchor to protein;0.0241169058792835!GO:0042765;GPI-anchor transamidase complex;0.0241169058792835!GO:0007160;cell-matrix adhesion;0.0246984140077951!GO:0017015;regulation of transforming growth factor beta receptor signaling pathway;0.0249641230661617!GO:0042168;heme metabolic process;0.0250968962341423!GO:0000096;sulfur amino acid metabolic process;0.0255211427512885!GO:0045941;positive regulation of transcription;0.0255499665888139!GO:0019752;carboxylic acid metabolic process;0.0259308017919899!GO:0005595;collagen type XII;0.0259308017919899!GO:0006607;NLS-bearing substrate import into nucleus;0.0259660079744731!GO:0031902;late endosome membrane;0.0261043713475662!GO:0007041;lysosomal transport;0.0264833718895586!GO:0045893;positive regulation of transcription, DNA-dependent;0.0268049055605101!GO:0043241;protein complex disassembly;0.0269228957079775!GO:0051539;4 iron, 4 sulfur cluster binding;0.0269228957079775!GO:0031589;cell-substrate adhesion;0.0269228957079775!GO:0005819;spindle;0.0271949914816325!GO:0008632;apoptotic program;0.0274693172639876!GO:0003678;DNA helicase activity;0.0275715620669513!GO:0006082;organic acid metabolic process;0.0281064801436598!GO:0006739;NADP metabolic process;0.028666947550212!GO:0030119;AP-type membrane coat adaptor complex;0.0286869411699822!GO:0030518;steroid hormone receptor signaling pathway;0.0289047844806537!GO:0007179;transforming growth factor beta receptor signaling pathway;0.0295545944794667!GO:0022408;negative regulation of cell-cell adhesion;0.0295897179983036!GO:0031272;regulation of pseudopodium formation;0.0300211006013661!GO:0031269;pseudopodium formation;0.0300211006013661!GO:0031344;regulation of cell projection organization and biogenesis;0.0300211006013661!GO:0031268;pseudopodium organization and biogenesis;0.0300211006013661!GO:0031346;positive regulation of cell projection organization and biogenesis;0.0300211006013661!GO:0031274;positive regulation of pseudopodium formation;0.0300211006013661!GO:0005801;cis-Golgi network;0.0300211006013661!GO:0016408;C-acyltransferase activity;0.0302300162227697!GO:0005774;vacuolar membrane;0.0302300162227697!GO:0003756;protein disulfide isomerase activity;0.0305227780153423!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0305227780153423!GO:0051045;negative regulation of membrane protein ectodomain proteolysis;0.0306525156890327!GO:0051043;regulation of membrane protein ectodomain proteolysis;0.0306525156890327!GO:0019206;nucleoside kinase activity;0.0309099080507007!GO:0000082;G1/S transition of mitotic cell cycle;0.0310894900597449!GO:0000279;M phase;0.0319538031084718!GO:0008484;sulfuric ester hydrolase activity;0.0321369016056336!GO:0008652;amino acid biosynthetic process;0.0321376337098811!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0323140297719273!GO:0044433;cytoplasmic vesicle part;0.0326388470526154!GO:0006417;regulation of translation;0.0332710799542128!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.0334888509882415!GO:0003702;RNA polymerase II transcription factor activity;0.0347069110631303!GO:0006635;fatty acid beta-oxidation;0.0347069110631303!GO:0031323;regulation of cellular metabolic process;0.0353113625889758!GO:0006405;RNA export from nucleus;0.0354883709058829!GO:0004656;procollagen-proline 4-dioxygenase activity;0.0382087586141453!GO:0031545;peptidyl-proline 4-dioxygenase activity;0.0382087586141453!GO:0030508;thiol-disulfide exchange intermediate activity;0.0387270303286152!GO:0030145;manganese ion binding;0.0389082944311245!GO:0001952;regulation of cell-matrix adhesion;0.0392311291122147!GO:0044452;nucleolar part;0.0393275180173147!GO:0008033;tRNA processing;0.040146973111229!GO:0043065;positive regulation of apoptosis;0.040675012362721!GO:0006611;protein export from nucleus;0.0407166299453522!GO:0030866;cortical actin cytoskeleton organization and biogenesis;0.0421653541938566!GO:0005591;collagen type VIII;0.042392553749278!GO:0005598;short-chain collagen;0.042392553749278!GO:0008234;cysteine-type peptidase activity;0.0426281141372276!GO:0000118;histone deacetylase complex;0.0426281141372276!GO:0045926;negative regulation of growth;0.0426547762680121!GO:0033673;negative regulation of kinase activity;0.0433547268108892!GO:0006469;negative regulation of protein kinase activity;0.0433547268108892!GO:0005637;nuclear inner membrane;0.0438921022688566!GO:0051052;regulation of DNA metabolic process;0.0441375208774393!GO:0031371;ubiquitin conjugating enzyme complex;0.0445981611872519!GO:0006302;double-strand break repair;0.0445981611872519!GO:0033559;unsaturated fatty acid metabolic process;0.0451638007137582!GO:0006636;unsaturated fatty acid biosynthetic process;0.0451638007137582!GO:0043068;positive regulation of programmed cell death;0.0453184510202582!GO:0006376;mRNA splice site selection;0.0453184510202582!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0453184510202582!GO:0030131;clathrin adaptor complex;0.0453670175796501!GO:0008538;proteasome activator activity;0.0453683049976021!GO:0030503;regulation of cell redox homeostasis;0.0458740911424771!GO:0017134;fibroblast growth factor binding;0.046095586108802!GO:0006779;porphyrin biosynthetic process;0.0475182286473234!GO:0033014;tetrapyrrole biosynthetic process;0.0475182286473234!GO:0003682;chromatin binding;0.0484456862800288!GO:0030031;cell projection biogenesis;0.0484879866980087!GO:0008475;procollagen-lysine 5-dioxygenase activity;0.048679166808449!GO:0008320;protein transmembrane transporter activity;0.0488907654294244!GO:0031461;cullin-RING ubiquitin ligase complex;0.0488907654294244!GO:0003988;acetyl-CoA C-acyltransferase activity;0.0488907654294244!GO:0001953;negative regulation of cell-matrix adhesion;0.0489584752342665 | |||
|sample_id=11553 | |||
|sample_note= | |||
|sample_sex=M | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=skin | |||
|top_motifs=GZF1:1.72731329843;ZNF238:1.69779817184;XBP1:1.52173227758;NR3C1:1.51822045134;ESR1:1.50978060698;NKX3-2:1.36523592818;NKX3-1:1.35982519421;TP53:1.35322484255;HAND1,2:1.30159537643;HMGA1,2:1.30073687297;TEAD1:1.26362484381;FOXL1:1.25662518092;GTF2A1,2:1.2016625179;NKX2-2,8:1.15111139135;RXR{A,B,G}:1.14882578611;TFAP4:1.11096092924;TAL1_TCF{3,4,12}:1.10947651161;KLF4:1.08558616876;HES1:1.05788917799;MYBL2:1.05301805467;NFIX:1.04262721766;UFEwm:1.02044062231;SRF:1.00447414234;TFCP2:0.996850172426;ATF6:0.991935065218;ALX4:0.9806648371;HBP1_HMGB_SSRP1_UBTF:0.95733334614;GFI1B:0.936242231406;SOX17:0.902004933487;EBF1:0.890327159403;GATA4:0.88308670832;PDX1:0.86897736396;IKZF1:0.864457278846;NFE2L1:0.808333311189;MAZ:0.805526104995;AIRE:0.804524782974;FOXD3:0.80000773078;SMAD1..7,9:0.799593602427;NFATC1..3:0.784369760964;HSF1,2:0.781797095782;HOX{A5,B5}:0.780027950245;GTF2I:0.774473175459;GCM1,2:0.746581259098;HMX1:0.723432580694;PRDM1:0.711117479619;MAFB:0.700555022902;GLI1..3:0.674874835052;TFAP2{A,C}:0.670130207571;TBX4,5:0.655754269781;ZNF384:0.655064584441;LHX3,4:0.648551059993;RXRA_VDR{dimer}:0.640289025934;TLX1..3_NFIC{dimer}:0.627521637472;TEF:0.613206535099;NANOG{mouse}:0.61247933079;MZF1:0.603090290715;NKX2-3_NKX2-5:0.588556732432;MTE{core}:0.572313729286;HIF1A:0.562492855506;HOX{A4,D4}:0.557253423937;PRRX1,2:0.526337387718;NR6A1:0.499061250565;EP300:0.493121080419;ZNF148:0.459037874562;EN1,2:0.443209428493;HLF:0.434288299455;EVI1:0.421119334888;SPZ1:0.409693150566;HOX{A6,A7,B6,B7}:0.406709970942;PPARG:0.394690456202;PAX5:0.389894643671;ZIC1..3:0.383456872693;GFI1:0.374942875398;MTF1:0.354970337876;CDC5L:0.353354726224;TFAP2B:0.339791045409;NFE2L2:0.336439617419;XCPE1{core}:0.334248800446;YY1:0.333141129239;PATZ1:0.28705632381;HIC1:0.240302607392;RREB1:0.236850433455;TBP:0.234402462843;FOXO1,3,4:0.227778141547;MEF2{A,B,C,D}:0.226934798356;ZNF423:0.199410871699;AHR_ARNT_ARNT2:0.192583727989;BACH2:0.182837997594;NHLH1,2:0.182818204003;TFDP1:0.174226439035;ADNP_IRX_SIX_ZHX:0.171074288271;NR1H4:0.170084174868;LEF1_TCF7_TCF7L1,2:0.140470869632;CEBPA,B_DDIT3:0.126397960253;MYFfamily:0.112520508744;CRX:0.111128347125;STAT5{A,B}:0.106932564145;ELK1,4_GABP{A,B1}:0.10094199862;PAX8:0.0613947315898;ZBTB6:0.0534827721736;POU1F1:0.0422950579113;EGR1..3:0.0255692501908;NKX2-1,4:0.0218692186758;NFE2:0.0214496409683;POU5F1:0.0117027551189;T:-0.0193286163477;PAX1,9:-0.0206975635621;IRF1,2:-0.0306675182101;TOPORS:-0.0387327416439;FOXA2:-0.0554630402226;DMAP1_NCOR{1,2}_SMARC:-0.0668790301024;HNF1A:-0.0673934507897;NRF1:-0.0810256907677;SP1:-0.0837303590386;RUNX1..3:-0.086682841047;RFX1:-0.105522230447;DBP:-0.115662822227;STAT1,3:-0.121091200041;FOS_FOS{B,L1}_JUN{B,D}:-0.125492885403;ONECUT1,2:-0.152144553345;ARID5B:-0.1830006699;ZNF143:-0.199391298539;SOX5:-0.205552123286;POU3F1..4:-0.209084313428;NKX6-1,2:-0.226655303317;MYB:-0.232914330586;STAT2,4,6:-0.233894765049;MED-1{core}:-0.245314016382;REST:-0.264986213089;FOSL2:-0.267497222099;ZFP161:-0.292404528584;PAX3,7:-0.305402517217;POU6F1:-0.307686958279;TGIF1:-0.333355168541;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.334202886865;bHLH_family:-0.352805814071;RBPJ:-0.366382080641;HNF4A_NR2F1,2:-0.373239592021;ALX1:-0.377530242004;FOXM1:-0.382842918413;NFKB1_REL_RELA:-0.401477551935;FOX{D1,D2}:-0.420920457536;SPI1:-0.440075269726;ETS1,2:-0.440552698934;ELF1,2,4:-0.441019381309;JUN:-0.489531514277;CREB1:-0.493471761592;NFIL3:-0.500346144089;PAX6:-0.505570732998;SREBF1,2:-0.527116252176;BPTF:-0.532600749165;ATF4:-0.544979641726;ATF2:-0.547866145417;SPIB:-0.56127952985;PAX2:-0.577643191106;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.58728636954;FOX{I1,J2}:-0.589603118557;CUX2:-0.598508941881;FOXP3:-0.603869246726;IRF7:-0.606753889749;RFX2..5_RFXANK_RFXAP:-0.624006178136;SOX2:-0.624757237333;AR:-0.64051837017;FOXN1:-0.657299565583;ATF5_CREB3:-0.662820983489;E2F1..5:-0.664480743353;SNAI1..3:-0.671688766106;FOXQ1:-0.681559552201;PAX4:-0.688248091306;ZEB1:-0.737850098801;OCT4_SOX2{dimer}:-0.811665513314;ZBTB16:-0.849297401956;BREu{core}:-0.853359026085;TLX2:-0.87734619452;ESRRA:-0.887155527937;NR5A1,2:-0.909807485109;PITX1..3:-0.921988830283;NFY{A,B,C}:-0.925165097024;FOX{F1,F2,J1}:-0.95651917376;SOX{8,9,10}:-0.972616299805;FOXP1:-0.980321539752;LMO2:-0.984867113065;NANOG:-0.996789689064;VSX1,2:-1.0062009977;GATA6:-1.01183379133;HOXA9_MEIS1:-1.04368351566;PBX1:-1.05873059243;RORA:-1.0593271516;CDX1,2,4:-1.07129980382;POU2F1..3:-1.16716450481;MYOD1:-1.22897031064;IKZF2:-1.30267950024 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11553-120C5;search_select_hide=table117:FF:11553-120C5 | |||
}} | }} |
Latest revision as of 18:08, 4 June 2020
Name: | Fibroblast - skin normal, donor1 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs11351 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11351
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11351
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.385 |
10 | 10 | 0.472 |
100 | 100 | 0.581 |
101 | 101 | 0.594 |
102 | 102 | 0.0342 |
103 | 103 | 0.655 |
104 | 104 | 0.719 |
105 | 105 | 0.615 |
106 | 106 | 0.935 |
107 | 107 | 0.563 |
108 | 108 | 0.96 |
109 | 109 | 0.474 |
11 | 11 | 0.74 |
110 | 110 | 0.891 |
111 | 111 | 0.535 |
112 | 112 | 0.697 |
113 | 113 | 7.25794e-4 |
114 | 114 | 0.569 |
115 | 115 | 0.315 |
116 | 116 | 0.109 |
117 | 117 | 0.268 |
118 | 118 | 0.618 |
119 | 119 | 0.523 |
12 | 12 | 0.586 |
120 | 120 | 0.896 |
121 | 121 | 0.712 |
122 | 122 | 0.651 |
123 | 123 | 6.87201e-5 |
124 | 124 | 0.629 |
125 | 125 | 0.826 |
126 | 126 | 0.883 |
127 | 127 | 0.74 |
128 | 128 | 0.998 |
129 | 129 | 0.431 |
13 | 13 | 0.361 |
130 | 130 | 0.113 |
131 | 131 | 0.786 |
132 | 132 | 0.222 |
133 | 133 | 0.537 |
134 | 134 | 0.513 |
135 | 135 | 0.135 |
136 | 136 | 0.0712 |
137 | 137 | 0.406 |
138 | 138 | 0.409 |
139 | 139 | 0.743 |
14 | 14 | 0.37 |
140 | 140 | 0.35 |
141 | 141 | 0.193 |
142 | 142 | 0.81 |
143 | 143 | 0.854 |
144 | 144 | 0.754 |
145 | 145 | 0.951 |
146 | 146 | 0.984 |
147 | 147 | 0.0511 |
148 | 148 | 0.514 |
149 | 149 | 0.00511 |
15 | 15 | 0.366 |
150 | 150 | 0.341 |
151 | 151 | 0.698 |
152 | 152 | 0.0568 |
153 | 153 | 0.2 |
154 | 154 | 0.882 |
155 | 155 | 0.00862 |
156 | 156 | 0.795 |
157 | 157 | 0.236 |
158 | 158 | 0.00668 |
159 | 159 | 0.707 |
16 | 16 | 0.105 |
160 | 160 | 0.579 |
161 | 161 | 0.34 |
162 | 162 | 0.775 |
163 | 163 | 0.804 |
164 | 164 | 0.687 |
165 | 165 | 0.532 |
166 | 166 | 0.0488 |
167 | 167 | 0.279 |
168 | 168 | 0.301 |
169 | 169 | 0.0551 |
17 | 17 | 0.905 |
18 | 18 | 0.144 |
19 | 19 | 0.0118 |
2 | 2 | 0.215 |
20 | 20 | 0.226 |
21 | 21 | 0.0464 |
22 | 22 | 0.261 |
23 | 23 | 0.302 |
24 | 24 | 0.358 |
25 | 25 | 0.3 |
26 | 26 | 0.515 |
27 | 27 | 0.595 |
28 | 28 | 0.283 |
29 | 29 | 0.716 |
3 | 3 | 0.802 |
30 | 30 | 0.131 |
31 | 31 | 0.776 |
32 | 32 | 2.26669e-11 |
33 | 33 | 0.433 |
34 | 34 | 0.834 |
35 | 35 | 0.556 |
36 | 36 | 0.0489 |
37 | 37 | 0.213 |
38 | 38 | 0.492 |
39 | 39 | 0.167 |
4 | 4 | 0.663 |
40 | 40 | 0.235 |
41 | 41 | 0.669 |
42 | 42 | 0.387 |
43 | 43 | 0.734 |
44 | 44 | 0.701 |
45 | 45 | 0.677 |
46 | 46 | 0.897 |
47 | 47 | 0.583 |
48 | 48 | 0.729 |
49 | 49 | 0.325 |
5 | 5 | 0.488 |
50 | 50 | 0.432 |
51 | 51 | 0.667 |
52 | 52 | 0.88 |
53 | 53 | 0.177 |
54 | 54 | 0.796 |
55 | 55 | 0.204 |
56 | 56 | 0.791 |
57 | 57 | 0.837 |
58 | 58 | 0.25 |
59 | 59 | 0.158 |
6 | 6 | 0.986 |
60 | 60 | 0.629 |
61 | 61 | 0.26 |
62 | 62 | 0.649 |
63 | 63 | 0.724 |
64 | 64 | 0.538 |
65 | 65 | 0.8 |
66 | 66 | 0.337 |
67 | 67 | 0.937 |
68 | 68 | 0.744 |
69 | 69 | 0.989 |
7 | 7 | 0.169 |
70 | 70 | 0.674 |
71 | 71 | 0.794 |
72 | 72 | 0.82 |
73 | 73 | 0.0577 |
74 | 74 | 0.48 |
75 | 75 | 0.319 |
76 | 76 | 0.44 |
77 | 77 | 0.0575 |
78 | 78 | 0.0926 |
79 | 79 | 0.0727 |
8 | 8 | 0.77 |
80 | 80 | 0.955 |
81 | 81 | 0.749 |
82 | 82 | 0.122 |
83 | 83 | 0.108 |
84 | 84 | 0.207 |
85 | 85 | 0.86 |
86 | 86 | 0.518 |
87 | 87 | 0.378 |
88 | 88 | 0.636 |
89 | 89 | 0.113 |
9 | 9 | 0.498 |
90 | 90 | 0.245 |
91 | 91 | 0.713 |
92 | 92 | 0.231 |
93 | 93 | 0.701 |
94 | 94 | 0.789 |
95 | 95 | 0.905 |
96 | 96 | 0.879 |
97 | 97 | 0.592 |
98 | 98 | 0.425 |
99 | 99 | 0.0107 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11351
FANTOM5 (FF) ontology
Direct parent terms
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0002320 (connective tissue cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
0000057 (fibroblast)
0002620 (skin fibroblast)
UBERON: Anatomy
0000468 (multi-cellular organism)
0002097 (skin of body)
0002199 (integument)
0002384 (connective tissue)
0000479 (tissue)
0000062 (organ)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0003102 (surface structure)
0002416 (integumental system)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000057 (fibroblast sample)
0000250 (human fibroblast of skin sample)
0000001 (sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)