FF:11230-116C6: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005732 | ||
|DRA_sample_Accession_RNASeq=sRNA-Seq@SAMD00005732 | |||
|accession_numbers=CAGE;DRX008370;DRR009242;DRZ000667;DRZ002052;DRZ012017;DRZ013402 | |||
|accession_numbers_RNASeq=sRNA-Seq;DRX037156;DRR041522;DRZ007164 | |||
|ancestors_in_anatomy_facet= | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0002371,CL:0000542,CL:0000219,CL:0000738,CL:0002087,CL:0002242,CL:0000255,CL:0000623 | |||
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|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000001,FF:0000119 | ||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr1:25256756..25256774,-!p1@RUNX3!2.43!482.92!RUNX3;;chr2:192015701..192015743,-!p1@STAT4!2.27!250.43!STAT4;;chr17:45810594..45810608,+!p1@TBX21!2.15!139.89!TBX21;;chr2:157189180..157189290,-!p1@NR4A2!1.94!422.63!NR4A2;;chr19:45971246..45971265,+!p1@FOSB!1.90!1377.44!FOSB;;chr2:68592406..68592424,+!p1@PLEK!1.89!76.64!PLEK;;chr19:54041669..54041697,+!p2@ZNF331!1.86!71.52!ZNF331;;chr1:26697243..26697258,-!p1@ZNF683!1.85!69.35!ZNF683;;chr19:54058073..54058088,+!p1@ZNF331!1.84!68.57!ZNF331;;chr9:117150254..117150271,-!p1@AKNA!1.82!170.83!AKNA;;chr2:61108878..61108891,+!p5@REL!1.81!63.64!REL;;chr7:50343634..50343717,+!p2@IKZF1!1.81!63.05!IKZF1;;chr6:106546808..106546833,+!p3@PRDM1!1.78!73.49!PRDM1;;chr2:192015677..192015691,-!p3@STAT4!1.78!59.11!STAT4;;chr20:50159198..50159299,-!p1@NFATC2!1.77!82.56!NFATC2;;chr3:63953435..63953499,+!p1@ATXN7!1.75!54.97!ATXN7;;chr10:35484053..35484076,+!p1@CREM!1.74!131.03!CREM;;chr10:8096772..8096787,+!p2@GATA3!1.72!60.49!GATA3;;chr15:60884706..60884743,-!p1@RORA!1.71!249.44!RORA;;chr2:145271342..145271377,-!p5@ZEB2!1.68!46.70!ZEB2;;chr14:75745523..75745537,+!p1@FOS!1.67!5105.66!FOS;;chr2:192015750..192015793,-!p2@STAT4!1.67!60.88!STAT4;;chr20:56195474..56195506,-!p1@ZBP1!1.66!44.33!ZBP1;;chr10:8096631..8096660,+!p1@GATA3!1.65!53.00!GATA3;;chr3:39195075..39195088,-!p1@CSRNP1!1.61!238.80!CSRNP1;;chr17:38020392..38020477,-!p1@IKZF3!1.61!39.80!IKZF3;;chr5:133451294..133451310,+!p2@TCF7!1.61!39.80!TCF7;;chr5:133450365..133450444,+!p1@TCF7!1.58!163.93!TCF7;;chr14:64971288..64971316,-!p2@ZBTB25!1.58!110.53!ZBTB25;;chr9:3525727..3525828,-!p2@RFX3!1.56!88.27!RFX3;;chr16:85932760..85932775,+!p1@IRF8!1.56!35.47!IRF8;;chr2:231090433..231090469,+!p1@SP140!1.56!35.47!SP140;;chr9:102584262..102584276,+!p1@NR4A3!1.55!75.86!NR4A3;;chr8:67525443..67525459,-!p2@MYBL1!1.54!49.85!MYBL1;;chrY:21906594..21906622,-!p1@KDM5D!1.54!33.69!KDM5D;;chr6:391743..391759,+!p1@IRF4!1.53!32.51!IRF4;;chr2:145277640..145277771,-!p1@ZEB2!1.51!403.52!ZEB2;;chr12:72056800..72056834,+!p1@THAP2!1.51!41.77!THAP2;;chr1:25291475..25291511,-!p2@RUNX3!1.51!31.13!RUNX3;;chr8:123793988..123794016,+!p1@ZHX2!1.50!52.80!ZHX2;;chr1:26697189..26697205,-!p2@ZNF683!1.49!29.95!ZNF683;;chr2:231090471..231090504,+!p2@SP140!1.49!29.75!SP140;;chr1:59249688..59249703,-!p3@JUN!1.48!168.46!JUN;;chr17:37934365..37934387,-!p2@IKZF3!1.47!28.77!IKZF3;;chr1:59249707..59249727,-!p1@JUN!1.46!1123.86!JUN;;chr8:81397820..81397836,+!p2@ZBTB10!1.46!34.48!ZBTB10;;chr4:57522166..57522260,-!p2@HOPX!1.45!30.93!HOPX;;chr5:131826457..131826514,-!p1@IRF1!1.44!998.75!IRF1;;chr19:16435625..16435682,+!p1@KLF2!1.42!774.53!KLF2;;chr10:35484090..35484104,+!p6@CREM!1.41!24.63!CREM;;chr6:106546834..106546850,+!p4@PRDM1!1.40!23.84!PRDM1;;chr7:104654690..104654704,+!p2@MLL5!1.38!45.12!MLL5;;chr8:123793252..123793266,+!p10@ZHX2!1.38!23.25!ZHX2;;chr21:36421347..36421380,-!p8@RUNX1!1.38!23.25!RUNX1;;chrX:106960285..106960299,-!p1@TSC22D3!1.37!585.18!TSC22D3;;chr8:81397846..81397860,+!p3@ZBTB10!1.37!27.98!ZBTB10;;chr4:57522513..57522548,-!p4@HOPX!1.37!22.46!HOPX;;chr3:5020939..5020952,+!p2@BHLHE40!1.36!67.58!BHLHE40;;chr7:50343895..50343936,+!p5@IKZF1!1.36!21.67!IKZF1;;chr3:23986824..23986848,+!p2@NR1D2!1.35!117.23!NR1D2;;chr10:35416142..35416169,+!p3@CREM!1.35!55.17!CREM;;chr8:81397876..81397898,+!p5@ZBTB10!1.35!25.02!ZBTB10;;chr18:46475696..46475713,-!p1@SMAD7!1.35!24.04!SMAD7;;chr6:91006518..91006570,-!p1@BACH2!1.34!47.68!BACH2;;chr4:109087445..109087463,-!p1@LEF1!1.34!20.89!LEF1;;chr4:57522598..57522664,-!p3@HOPX!1.34!20.89!HOPX;;chr1:151030536..151030549,+!p8@MLLT11!1.34!20.69!MLLT11;;chr4:103422499..103422632,+!p1@NFKB1!1.33!412.19!NFKB1;;chr10:3824332..3824425,-!p4@KLF6!1.32!31.92!KLF6;;chr12:72056773..72056796,+!p3@THAP2!1.29!24.04!THAP2;;chr6:106546786..106546802,+!p6@PRDM1!1.29!18.32!PRDM1;;chr7:137620650..137620677,-!p3@CREB3L2!1.29!18.32!CREB3L2;;chr17:38497662..38497713,+!p4@RARA!1.28!21.08!RARA;;chr19:12902289..12902307,+!p1@JUNB!1.27!3938.05!JUNB;;chr7:104654718..104654741,+!p3@MLL5!1.27!25.61!MLL5;;chr3:71542615..71542644,-!p12@FOXP1!1.27!17.54!FOXP1;;chr14:35873947..35873965,-!p1@NFKBIA!1.26!1047.02!NFKBIA;;chr2:61108695..61108753,+!p1@REL!1.26!115.46!REL;;chr9:102584241..102584261,+!p4@NR4A3!1.26!26.60!NR4A3;;chr3:18486354..18486377,-!p2@SATB1!1.26!21.67!SATB1;;chr11:47400078..47400106,-!p1@SPI1!1.26!17.34!SPI1;;chr2:68592394..68592405,+!p2@PLEK!1.26!17.14!PLEK;;chr1:10754477..10754517,-!p1@CASZ1!1.25!27.98!CASZ1;;chr3:27763807..27763822,-!p1@EOMES!1.24!16.55!EOMES;;chr6:106546731..106546755,+!p5@PRDM1!1.24!16.35!PRDM1;;chr19:12721790..12721810,+!p2@ZNF791!1.23!43.74!ZNF791;;chr19:19729477..19729542,-!p1@PBX4!1.23!34.28!PBX4;;chr19:45972701..45972774,+!p2@FOSB!1.23!21.87!FOSB;;chr13:74707894..74707947,-!p6@KLF12!1.22!17.14!KLF12;;chr7:50344289..50344323,+!p1@IKZF1!1.22!15.57!IKZF1;;chr3:101546827..101546847,+!p2@NFKBIZ!1.21!21.28!NFKBIZ;;chr3:39195037..39195069,-!p2@CSRNP1!1.20!91.23!CSRNP1;;chrX:106960221..106960236,-!p3@TSC22D3!1.20!40.98!TSC22D3;;chr9:102584128..102584144,+!p3@NR4A3!1.20!28.18!NR4A3;;chr11:67007611..67007622,+!p6@KDM2A!1.18!18.91!KDM2A;;chr10:104154415..104154434,+!p5@NFKB2!1.18!14.19!NFKB2;;chr2:208394817..208394834,+!p3@CREB1!1.17!55.56!CREB1;;chr3:71355163..71355209,-!p5@FOXP1!1.17!19.31!FOXP1;;chr11:85375237..85375277,-!p4@CREBZF!1.17!15.96!CREBZF;;chr10:104154246..104154347,+!p3@NFKB2!1.16!80.98!NFKB2;;chrX:106960180..106960197,-!p2@TSC22D3!1.16!50.64!TSC22D3;;chr3:39195139..39195150,-!p3@CSRNP1!1.16!16.94!CSRNP1;;chr2:214017168..214017189,-!p8@IKZF2!1.16!13.60!IKZF2;;chr19:54041645..54041661,+!p5@ZNF331!1.16!13.60!ZNF331;;chr16:89789271..89789291,+!p5@ZNF276!1.15!13.20!ZNF276;;chr7:50344251..50344288,+!p3@IKZF1!1.15!13.20!IKZF1;;chr5:133451347..133451358,+!p3@TCF7!1.15!13.00!TCF7;;chr2:43453734..43453751,-!p1@ZFP36L2!1.14!1359.12!ZFP36L2;;chr11:67007548..67007610,+!p3@KDM2A!1.14!93.79!KDM2A;;chr15:57211634..57211657,+!p5@TCF12!1.14!19.31!TCF12;;chr6:91006575..91006602,-!p2@BACH2!1.14!18.91!BACH2;;chr8:60031619..60031676,-!p1@TOX!1.13!26.99!TOX;;chr8:102218439..102218455,-!p3@ZNF706!1.13!12.61!ZNF706;;chr2:122042770..122042785,-!p1@TFCP2L1!1.13!12.61!TFCP2L1;;chr4:38665769..38665801,+!p2@KLF3!1.12!110.73!KLF3;;chr22:38597987..38598021,+!p2@MAFF!1.12!75.27!MAFF;;chr2:61108808..61108821,+!p3@REL!1.12!15.57!REL;;chr19:47616992..47617011,-!p4@ZC3H4!1.11!25.42!ZC3H4;;chr17:45810816..45810838,+!p2@TBX21!1.11!12.02!TBX21;;chr1:37940170..37940190,+!p1@ZC3H12A!1.10!143.83!ZC3H12A;;chr17:38020557..38020572,-!p4@IKZF3!1.10!11.62!IKZF3;;chr2:28616358..28616380,+!p3@FOSL2!1.09!59.11!FOSL2;;chr14:35872962..35873025,-!p3@NFKBIA!1.09!28.57!NFKBIA;;chr8:67525473..67525518,-!p1@MYBL1!1.09!26.21!MYBL1;;chr6:12009042..12009092,+!p6@HIVEP1!1.09!14.78!HIVEP1;;chr4:57522674..57522699,-!p5@HOPX!1.09!11.43!HOPX;;chr12:51158359..51158395,+!p4@ATF1!1.09!11.23!ATF1;;chr14:64971461..64971542,+!p1@ZBTB1!1.08!224.02!ZBTB1;;chr12:72056749..72056767,+!p6@THAP2!1.08!12.41!THAP2;;chr10:3827389..3827408,-!p1@KLF6!1.07!833.83!KLF6;;chr12:57914286..57914304,-!p1@DDIT3!1.07!389.33!DDIT3;;chr2:97202480..97202499,+!p1@ARID5A!1.07!109.94!ARID5A;;chr3:18487057..18487105,-!p4@SATB1!1.07!10.84!SATB1;;chr3:71542684..71542720,-!p18@FOXP1!1.07!10.84!FOXP1;;chrY:2803415..2803468,+!p1@ZFY!1.07!10.84!ZFY;;chr14:99738138..99738163,-!p1@BCL11B!1.07!10.64!BCL11B;;chr13:41593425..41593480,-!p1@ELF1!1.06!67.98!ELF1;;chr9:32550839..32550962,-!p3@TOPORS!1.06!26.40!TOPORS;;chr11:113930425..113930471,+!p1@ZBTB16!1.06!15.37!ZBTB16;;chr21:36421147..36421193,-!p10@RUNX1!1.06!10.44!RUNX1;;chr17:38020516..38020544,-!p5@IKZF3!1.06!10.44!IKZF3;;chr19:18392422..18392440,-!p1@JUND!1.05!1419.80!JUND;;chr1:59249645..59249656,-!p4@JUN!1.05!25.81!JUN;;chr17:7388010..7388017,-!p5@ZBTB4!1.05!17.54!ZBTB4;;chr7:106809470..106809481,+!p2@HBP1!1.05!14.58!HBP1;;chr16:29819579..29819591,+!p32@MAZ!1.05!10.25!MAZ;;chr16:68119324..68119364,+!p1@NFATC3!1.04!44.92!NFATC3;;chr1:91487774..91487802,-!p2@ZNF644!1.04!26.99!ZNF644;;chr9:102584159..102584174,+!p2@NR4A3!1.04!18.32!NR4A3;;chr7:50344144..50344157,+!p6@IKZF1!1.04!10.05!IKZF1;;chr8:123794038..123794056,+!p5@ZHX2!1.03!9.65!ZHX2;;chr3:101568349..101568365,+!p1@NFKBIZ!1.02!498.29!NFKBIZ;;chr7:64838786..64838809,+!p2@ZNF92!1.02!55.37!ZNF92;;chr2:157189617..157189667,-!p4@NR4A2!1.02!9.46!NR4A2;;chr3:71179699..71179744,-!p2@FOXP1!1.01!70.93!FOXP1;;chr6:143266297..143266356,-!p1@HIVEP2!1.01!44.92!HIVEP2;;chr14:75988771..75988826,+!p1@BATF!1.01!12.41!BATF;;chr15:31619407..31619419,+!p9@KLF13!1.01!11.62!KLF13;;chr20:44600199..44600219,-!p3@ZNF335!1.00!12.41!ZNF335;;chr14:69262947..69262986,-!p3@ZFP36L1!1.00!11.03!ZFP36L1;;chr20:57757940..57757966,+!p@chr20:57757940..57757966,+!1.00!9.06!ZNF831;;chr9:102584278..102584285,+!p5@NR4A3!1.00!9.06!NR4A3;;chr11:128392085..128392232,-!p1@ETS1!0.99!302.05!ETS1;;chr2:174828545..174828644,-!p1@SP3!0.99!138.12!SP3;;chr2:145275162..145275202,-!p2@ZEB2!0.99!52.61!ZEB2;;chr21:36421535..36421610,-!p2@RUNX1!0.99!32.12!RUNX1;;chr13:74708029..74708077,-!p2@KLF12!0.99!25.61!KLF12;;chr15:60884747..60884774,-!p3@RORA!0.99!21.87!RORA;;chr5:142782823..142782854,-!p3@NR3C1!0.99!12.61!NR3C1;;chr19:18391615..18391637,-!p5@JUND!0.99!11.62!JUND;;chr4:83822199..83822239,+!p2@THAP9!0.99!10.44!THAP9;;chr7:137620684..137620711,-!p4@CREB3L2!0.99!8.87!CREB3L2;;chr7:99680193..99680204,-!p2@ZNF3!0.99!8.87!ZNF3;;chr1:151030388..151030419,+!p9@MLLT11!0.99!8.67!MLLT11;;chr1:25256175..25256228,-!p5@RUNX3!0.99!8.67!RUNX3;;chr15:31619326..31619390,+!p2@KLF13!0.98!101.08!KLF13;;chr14:90085458..90085557,-!p1@FOXN3!0.98!92.01!FOXN3;;chr6:45390300..45390335,+!p4@RUNX2!0.98!13.40!RUNX2;;chr14:75746722..75746777,+!p2@FOS!0.98!11.03!FOS;;chr4:109090075..109090095,-!p2@LEF1!0.98!8.47!LEF1;;chr19:50529028..50529040,+!p5@ZNF473!0.98!8.47!ZNF473;;chr5:172483347..172483407,+!p1@C5orf41!0.97!64.03!CREBRF;;chr19:45252008..45252024,+!p2@BCL3!0.97!27.98!BCL3;;chr8:71316428..71316459,-!p2@NCOA2!0.97!14.38!NCOA2;;chr20:52226313..52226350,-!p3@ZNF217!0.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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000542;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000623;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000738;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000988 | |||
|ffid_belonging_in_development=CL:0000134,CL:0000051 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 43: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Natural%2520Killer%2520Cells%252c%2520donor1.CNhs10859.11230-116C6.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Natural%2520Killer%2520Cells%252c%2520donor1.CNhs10859.11230-116C6.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Natural%2520Killer%2520Cells%252c%2520donor1.CNhs10859.11230-116C6.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Natural%2520Killer%2520Cells%252c%2520donor1.CNhs10859.11230-116C6.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Natural%2520Killer%2520Cells%252c%2520donor1.CNhs10859.11230-116C6.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11230-116C6 | |||
|is_a=EFO:0002091;;FF:0000119 | |||
|is_obsolete= | |||
|library_id=CNhs10859 | |||
|library_id_phase_based=2:CNhs10859 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11230 | |||
|microRNAs_nonnovel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer/#/human#srna;sample;SRhi10010.ATGTCA.11230 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11230 | |||
|microRNAs_novel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer_novel/#/human#srna;sample;SRhi10010.ATGTCA.11230 | |||
|name=Natural Killer Cells, donor1 | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs10859,LSID702,release008,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=SRhi10010,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0.0390526553261436,0,0,0,0.0781053106522872,0.178573448762681,0.144281939746476,-0.073137929498756,-0.282403560576942,0,0,0,0,0,0,0,0,0,0,0,0.0781053106522872,0,0.0483723583589069,0,0,0,0,0.144281939746476,0.0463240434784188,0,0,-0.132956589778862,0,0,0,0,0,0,0,0.0781053106522872,0,0,0.0781053106522872,0,-0.005999377286202,0,0.0781053106522872,0,0,0,0,0,0,0.197281591438884,0,0,0,0,0,-0.0317854268395308,0.0781053106522872,0.0472895785038712,0,0.25239739930628,0.155053772093183,0,0.0781053106522872,0,0,0,0,0.25239739930628,0,0,0,1.9360828492441,0,0,0.201695368707335,0,0,0,0.122892065593374,0,0,0,0.0390526553261436,0,0,-0.108843756037179,0,0,0,0.0506895356285675,0.341621937252745,0.0390526553261436,0,0.169445739424534,0,0.54040627282427,-0.138477200800895,0,0,0,0,0,0.250347230453892,0,0,0,0,0,0,0,0,0,0,0,-0.0573209385963175,0.0781053106522872,0,0,-4.18831399850994e-05,-0.0253372740537612,0.144281939746476,0,0,0,0,0 | |||
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| |||
|rna_box=116 | |||
|rna_catalog_number=3H100-50-10 | |||
|rna_concentration=0.873 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-TRIzol-isopropanol-v1.0 | |||
|rna_lot_number=NK725 | |||
|rna_od260/230= | |||
|rna_od260/280= | |||
|rna_position=C6 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=116C6 | |||
|rna_weight_ug=10 | |||
|rnaseq_library_id=SRhi10010.ATGTCA | |||
|sample_age=47 | |||
|sample_category=primary cells | |||
|sample_cell_catalog=N/A | |||
|sample_cell_line= | |||
|sample_cell_lot=N/A | |||
|sample_cell_type=natural killer cell | |||
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest) | |||
|sample_company=3HBiomedical | |||
|sample_description= | |||
|sample_dev_stage=47 years old adult | |||
|sample_disease= | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=C | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;7.62924212228819e-215!GO:0043227;membrane-bound organelle;4.63800179065906e-188!GO:0043231;intracellular membrane-bound organelle;8.42158923981232e-188!GO:0043226;organelle;7.35086210449673e-176!GO:0043229;intracellular organelle;2.98896122222067e-175!GO:0005737;cytoplasm;2.82377170869456e-122!GO:0005634;nucleus;8.97875169271625e-114!GO:0043170;macromolecule metabolic process;1.79462308090321e-102!GO:0044422;organelle part;3.59876904363334e-102!GO:0044446;intracellular organelle part;1.24472165490142e-100!GO:0044237;cellular metabolic process;6.0752465728354e-95!GO:0044238;primary metabolic process;3.68096530162686e-94!GO:0044428;nuclear part;9.54964916696393e-80!GO:0032991;macromolecular complex;5.35691243480336e-79!GO:0043283;biopolymer metabolic process;2.13141041693239e-77!GO:0003723;RNA binding;3.42796090744302e-75!GO:0044444;cytoplasmic part;5.98585722795668e-74!GO:0005515;protein binding;1.4636027722411e-69!GO:0030529;ribonucleoprotein complex;3.88739535870941e-67!GO:0010467;gene expression;2.12966017861633e-65!GO:0043233;organelle lumen;1.35348973294207e-62!GO:0031974;membrane-enclosed lumen;1.35348973294207e-62!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;6.31757900688473e-59!GO:0031981;nuclear lumen;4.25701726778763e-51!GO:0019538;protein metabolic process;6.69212159333475e-49!GO:0033036;macromolecule localization;1.53792310551705e-47!GO:0044267;cellular protein metabolic process;4.28665168294828e-47!GO:0006396;RNA processing;1.07560939373975e-46!GO:0003676;nucleic acid binding;2.79832174115675e-46!GO:0044260;cellular macromolecule metabolic process;4.17881547830702e-46!GO:0006412;translation;2.86669096209466e-45!GO:0015031;protein transport;6.62586433245868e-45!GO:0045184;establishment of protein localization;1.9323140008625e-43!GO:0008104;protein localization;2.32653701645475e-43!GO:0016071;mRNA metabolic process;1.09599006998e-42!GO:0043234;protein complex;8.14200067983406e-40!GO:0016070;RNA metabolic process;2.309661451129e-39!GO:0008380;RNA splicing;2.8378922208836e-37!GO:0006397;mRNA processing;6.7390874632991e-36!GO:0009059;macromolecule biosynthetic process;3.45680460738165e-34!GO:0016043;cellular component organization and biogenesis;4.69088479348367e-34!GO:0005840;ribosome;1.56492807714408e-33!GO:0005654;nucleoplasm;2.64843365947801e-33!GO:0046907;intracellular transport;8.49251146394452e-33!GO:0031090;organelle membrane;1.30630332624119e-32!GO:0006886;intracellular protein transport;4.1182220148817e-31!GO:0005739;mitochondrion;4.48000767073333e-31!GO:0006259;DNA metabolic process;3.02878329471341e-30!GO:0005829;cytosol;8.91049317879392e-30!GO:0003735;structural constituent of ribosome;9.89790675664691e-30!GO:0031967;organelle envelope;3.6081102784653e-29!GO:0031975;envelope;7.47902793554332e-29!GO:0000166;nucleotide binding;4.25530371390804e-28!GO:0005681;spliceosome;6.86937721750469e-28!GO:0044451;nucleoplasm part;1.31867683317797e-27!GO:0033279;ribosomal subunit;2.53715144577546e-27!GO:0065003;macromolecular complex assembly;4.96684436100593e-27!GO:0012501;programmed cell death;4.89110158356926e-26!GO:0006915;apoptosis;5.69858391933915e-26!GO:0006512;ubiquitin cycle;8.01607327392684e-26!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.05922923839579e-25!GO:0009058;biosynthetic process;3.89048944519839e-25!GO:0008219;cell death;4.35562752497852e-25!GO:0016265;death;4.35562752497852e-25!GO:0022613;ribonucleoprotein complex biogenesis and assembly;5.72108557654684e-25!GO:0050794;regulation of cellular process;9.4235843860496e-25!GO:0051641;cellular localization;1.25292051464273e-24!GO:0051649;establishment of cellular localization;1.79756733731591e-24!GO:0043412;biopolymer modification;2.12455146910238e-24!GO:0044249;cellular biosynthetic process;3.53250069314082e-24!GO:0044429;mitochondrial part;5.33778200434012e-24!GO:0022607;cellular component assembly;6.0250861688655e-24!GO:0006996;organelle organization and biogenesis;5.6297492543029e-23!GO:0008134;transcription factor binding;2.40181138614009e-22!GO:0006464;protein modification process;9.77094292529363e-22!GO:0044445;cytosolic part;1.82165837728535e-21!GO:0043687;post-translational protein modification;5.32674690188081e-21!GO:0032553;ribonucleotide binding;2.45066589547418e-20!GO:0032555;purine ribonucleotide binding;2.45066589547418e-20!GO:0017111;nucleoside-triphosphatase activity;1.37769957976165e-19!GO:0017076;purine nucleotide binding;3.33633138034896e-19!GO:0016462;pyrophosphatase activity;3.33732574901831e-19!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;3.74866110626424e-19!GO:0019941;modification-dependent protein catabolic process;3.74866110626424e-19!GO:0043632;modification-dependent macromolecule catabolic process;3.74866110626424e-19!GO:0051603;proteolysis involved in cellular protein catabolic process;3.9871449062019e-19!GO:0006511;ubiquitin-dependent protein catabolic process;4.70490169183936e-19!GO:0016817;hydrolase activity, acting on acid anhydrides;4.75420930753217e-19!GO:0019222;regulation of metabolic process;7.2752615529888e-19!GO:0016874;ligase activity;8.37552288713543e-19!GO:0044257;cellular protein catabolic process;1.12995124813008e-18!GO:0016604;nuclear body;1.69214251582755e-18!GO:0050789;regulation of biological process;1.69214251582755e-18!GO:0006605;protein targeting;2.71952017329892e-18!GO:0044265;cellular macromolecule catabolic process;3.83892839351142e-18!GO:0006913;nucleocytoplasmic transport;4.43726173413219e-18!GO:0042981;regulation of apoptosis;8.42249379327373e-18!GO:0051169;nuclear transport;1.02757153193673e-17!GO:0005730;nucleolus;1.2680276816304e-17!GO:0043067;regulation of programmed cell death;1.55395527661474e-17!GO:0022618;protein-RNA complex assembly;2.06854196638117e-17!GO:0007049;cell cycle;6.11639693295701e-17!GO:0005524;ATP binding;1.01890997316484e-16!GO:0032559;adenyl ribonucleotide binding;2.73355900342426e-16!GO:0043228;non-membrane-bound organelle;4.1687548454533e-16!GO:0043232;intracellular non-membrane-bound organelle;4.1687548454533e-16!GO:0005740;mitochondrial envelope;4.93619326452465e-16!GO:0031323;regulation of cellular metabolic process;6.49742911885489e-16!GO:0016607;nuclear speck;9.07292621615953e-16!GO:0006325;establishment and/or maintenance of chromatin architecture;9.07292621615953e-16!GO:0043285;biopolymer catabolic process;9.49479205220895e-16!GO:0006974;response to DNA damage stimulus;1.49657321062563e-15!GO:0031966;mitochondrial membrane;1.60901504041387e-15!GO:0051276;chromosome organization and biogenesis;1.94900389930206e-15!GO:0030554;adenyl nucleotide binding;4.47305326256214e-15!GO:0006323;DNA packaging;5.01521695551631e-15!GO:0019866;organelle inner membrane;8.9228291627199e-15!GO:0008135;translation factor activity, nucleic acid binding;9.9415015423221e-15!GO:0015935;small ribosomal subunit;1.40942738967959e-14!GO:0005635;nuclear envelope;2.23894091687031e-14!GO:0006350;transcription;2.43819437798151e-14!GO:0031965;nuclear membrane;6.01237091336154e-14!GO:0006119;oxidative phosphorylation;6.14597962803456e-14!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);6.98760672657672e-14!GO:0010468;regulation of gene expression;9.52768006933656e-14!GO:0015934;large ribosomal subunit;1.08840677669262e-13!GO:0012505;endomembrane system;1.73828039671691e-13!GO:0048523;negative regulation of cellular process;1.74174743389155e-13!GO:0003712;transcription cofactor activity;2.13630458757793e-13!GO:0042623;ATPase activity, coupled;3.02783294764083e-13!GO:0004386;helicase activity;4.79438042544578e-13!GO:0016887;ATPase activity;4.80005489576603e-13!GO:0009057;macromolecule catabolic process;5.90637905049118e-13!GO:0030163;protein catabolic process;7.84145943409051e-13!GO:0000398;nuclear mRNA splicing, via spliceosome;8.694264501286e-13!GO:0000375;RNA splicing, via transesterification reactions;8.694264501286e-13!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;8.694264501286e-13!GO:0006366;transcription from RNA polymerase II promoter;9.28161753096354e-13!GO:0065007;biological regulation;9.32980311925085e-13!GO:0006793;phosphorus metabolic process;9.68259726117589e-13!GO:0006796;phosphate metabolic process;9.68259726117589e-13!GO:0017038;protein import;1.32316006809691e-12!GO:0005743;mitochondrial inner membrane;1.77047496811801e-12!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.88833704946432e-12!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.88833704946432e-12!GO:0006281;DNA repair;1.92979818325985e-12!GO:0048770;pigment granule;2.47727393628721e-12!GO:0042470;melanosome;2.47727393628721e-12!GO:0007243;protein kinase cascade;2.96571310867047e-12!GO:0016568;chromatin modification;5.68656462461933e-12!GO:0051726;regulation of cell cycle;7.22131390562623e-12!GO:0022402;cell cycle process;7.54399937074468e-12!GO:0008639;small protein conjugating enzyme activity;9.57388457178322e-12!GO:0048519;negative regulation of biological process;9.57388457178322e-12!GO:0044453;nuclear membrane part;9.70763256626481e-12!GO:0006457;protein folding;1.19523358760056e-11!GO:0008026;ATP-dependent helicase activity;1.2357924918981e-11!GO:0004842;ubiquitin-protein ligase activity;1.26154413785402e-11!GO:0000074;regulation of progression through cell cycle;1.53838028600913e-11!GO:0032774;RNA biosynthetic process;1.89188248478071e-11!GO:0006351;transcription, DNA-dependent;2.2196914613385e-11!GO:0000502;proteasome complex (sensu Eukaryota);2.32417602391638e-11!GO:0003743;translation initiation factor activity;2.49275324760211e-11!GO:0005794;Golgi apparatus;2.67950846317229e-11!GO:0007249;I-kappaB kinase/NF-kappaB cascade;3.52145246664748e-11!GO:0016192;vesicle-mediated transport;3.62871822409661e-11!GO:0019787;small conjugating protein ligase activity;5.02162452102212e-11!GO:0006413;translational initiation;6.00010083836166e-11!GO:0044455;mitochondrial membrane part;6.82306668206152e-11!GO:0045449;regulation of transcription;7.19865431906976e-11!GO:0050657;nucleic acid transport;8.19393922346373e-11!GO:0051236;establishment of RNA localization;8.19393922346373e-11!GO:0050658;RNA transport;8.19393922346373e-11!GO:0016310;phosphorylation;8.54093401721148e-11!GO:0031324;negative regulation of cellular metabolic process;8.61046357887253e-11!GO:0044248;cellular catabolic process;8.93995471720023e-11!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;9.58001531871407e-11!GO:0006606;protein import into nucleus;9.58001531871407e-11!GO:0051170;nuclear import;9.60349062495405e-11!GO:0006403;RNA localization;1.08816285760803e-10!GO:0005694;chromosome;1.35014899831711e-10!GO:0006446;regulation of translational initiation;1.74898884976631e-10!GO:0008270;zinc ion binding;2.13017466357429e-10!GO:0051246;regulation of protein metabolic process;2.30090547671119e-10!GO:0005768;endosome;2.39257178020898e-10!GO:0048193;Golgi vesicle transport;3.25673457166851e-10!GO:0007242;intracellular signaling cascade;3.6593330597598e-10!GO:0031980;mitochondrial lumen;3.72984007806114e-10!GO:0005759;mitochondrial matrix;3.72984007806114e-10!GO:0005643;nuclear pore;4.54370746721676e-10!GO:0065009;regulation of a molecular function;7.0543144337967e-10!GO:0006333;chromatin assembly or disassembly;1.21617687516035e-09!GO:0009719;response to endogenous stimulus;1.21617687516035e-09!GO:0005746;mitochondrial respiratory chain;1.26185483166585e-09!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;1.676539483309e-09!GO:0006355;regulation of transcription, DNA-dependent;2.2409942649594e-09!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.44005849789112e-09!GO:0009892;negative regulation of metabolic process;2.7097035510353e-09!GO:0065004;protein-DNA complex assembly;2.75848778586185e-09!GO:0044427;chromosomal part;3.32285538830333e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;5.00448851644899e-09!GO:0016564;transcription repressor activity;5.51054740479981e-09!GO:0042254;ribosome biogenesis and assembly;5.62044996093317e-09!GO:0016563;transcription activator activity;5.86223034069919e-09!GO:0051028;mRNA transport;5.9487049374639e-09!GO:0051082;unfolded protein binding;7.15212744990372e-09!GO:0016881;acid-amino acid ligase activity;7.71932628934392e-09!GO:0003713;transcription coactivator activity;1.00504477011561e-08!GO:0050136;NADH dehydrogenase (quinone) activity;1.02768217073649e-08!GO:0003954;NADH dehydrogenase activity;1.02768217073649e-08!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.02768217073649e-08!GO:0016481;negative regulation of transcription;1.03028568133847e-08!GO:0043069;negative regulation of programmed cell death;1.19227096884513e-08!GO:0043566;structure-specific DNA binding;1.28143694177195e-08!GO:0043065;positive regulation of apoptosis;1.42147193322986e-08!GO:0006917;induction of apoptosis;1.8957362040412e-08!GO:0043066;negative regulation of apoptosis;1.92349823206292e-08!GO:0043068;positive regulation of programmed cell death;2.53363490304367e-08!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;2.90069278449723e-08!GO:0016772;transferase activity, transferring phosphorus-containing groups;3.11797676940376e-08!GO:0012502;induction of programmed cell death;3.36910859472818e-08!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;3.79991204865297e-08!GO:0045786;negative regulation of progression through cell cycle;4.04206000570681e-08!GO:0046930;pore complex;4.58416042984883e-08!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;5.62273449148622e-08!GO:0006916;anti-apoptosis;5.98557457378801e-08!GO:0065002;intracellular protein transport across a membrane;6.71808438424742e-08!GO:0019899;enzyme binding;7.59473661702028e-08!GO:0003677;DNA binding;7.66393328479075e-08!GO:0032446;protein modification by small protein conjugation;8.08446892715165e-08!GO:0003697;single-stranded DNA binding;8.43756580077401e-08!GO:0016740;transferase activity;8.79181963617612e-08!GO:0019829;cation-transporting ATPase activity;1.02766830263414e-07!GO:0042775;organelle ATP synthesis coupled electron transport;1.03636595802769e-07!GO:0042773;ATP synthesis coupled electron transport;1.03636595802769e-07!GO:0008565;protein transporter activity;1.05311436377614e-07!GO:0000785;chromatin;1.14826238508795e-07!GO:0016567;protein ubiquitination;1.44001704848614e-07!GO:0016787;hydrolase activity;2.8057490282656e-07!GO:0006417;regulation of translation;2.87460370026893e-07!GO:0030964;NADH dehydrogenase complex (quinone);2.87460370026893e-07!GO:0045271;respiratory chain complex I;2.87460370026893e-07!GO:0005747;mitochondrial respiratory chain complex I;2.87460370026893e-07!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;2.91982570664569e-07!GO:0048522;positive regulation of cellular process;3.60515662769556e-07!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;5.02621856917099e-07!GO:0046914;transition metal ion binding;9.51955724245844e-07!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;1.0402683748814e-06!GO:0044432;endoplasmic reticulum part;1.04742918794e-06!GO:0000151;ubiquitin ligase complex;1.1586169094186e-06!GO:0006357;regulation of transcription from RNA polymerase II promoter;1.23260793270062e-06!GO:0005783;endoplasmic reticulum;1.24207276738718e-06!GO:0016072;rRNA metabolic process;1.53660837060111e-06!GO:0030532;small nuclear ribonucleoprotein complex;1.54859925912475e-06!GO:0006364;rRNA processing;1.81881762494334e-06!GO:0050790;regulation of catalytic activity;2.03106079339668e-06!GO:0044440;endosomal part;2.05857294589656e-06!GO:0010008;endosome membrane;2.05857294589656e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;2.39066563535895e-06!GO:0031326;regulation of cellular biosynthetic process;2.44591751383123e-06!GO:0051186;cofactor metabolic process;2.84221513430402e-06!GO:0051168;nuclear export;2.89879872186458e-06!GO:0004674;protein serine/threonine kinase activity;2.95059516536063e-06!GO:0046649;lymphocyte activation;3.00184963240394e-06!GO:0006888;ER to Golgi vesicle-mediated transport;3.05861276362669e-06!GO:0009615;response to virus;3.50883551018798e-06!GO:0003724;RNA helicase activity;3.57862892602068e-06!GO:0006260;DNA replication;3.61231205001626e-06!GO:0000278;mitotic cell cycle;3.66312618512372e-06!GO:0005525;GTP binding;4.95510240777271e-06!GO:0005793;ER-Golgi intermediate compartment;5.01876031740614e-06!GO:0009259;ribonucleotide metabolic process;5.24818093428825e-06!GO:0009889;regulation of biosynthetic process;5.30393376155416e-06!GO:0006399;tRNA metabolic process;5.94974090724431e-06!GO:0006461;protein complex assembly;6.01807705074274e-06!GO:0005770;late endosome;6.31000305921186e-06!GO:0003924;GTPase activity;6.32875843179504e-06!GO:0006401;RNA catabolic process;6.5040157332671e-06!GO:0005773;vacuole;6.61234888657771e-06!GO:0009260;ribonucleotide biosynthetic process;7.14407820229793e-06!GO:0009060;aerobic respiration;7.28740367910638e-06!GO:0045321;leukocyte activation;7.3190622858399e-06!GO:0015986;ATP synthesis coupled proton transport;7.61646314208707e-06!GO:0015985;energy coupled proton transport, down electrochemical gradient;7.61646314208707e-06!GO:0000245;spliceosome assembly;8.28339394595584e-06!GO:0005839;proteasome core complex (sensu Eukaryota);8.70118731949126e-06!GO:0007264;small GTPase mediated signal transduction;8.78424422138381e-06!GO:0031497;chromatin assembly;8.83894209448883e-06!GO:0042110;T cell activation;8.9024610374388e-06!GO:0008632;apoptotic program;9.05282055342102e-06!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;9.54631337629444e-06!GO:0009967;positive regulation of signal transduction;9.85826656379459e-06!GO:0016363;nuclear matrix;1.04861482573941e-05!GO:0005761;mitochondrial ribosome;1.10485876036298e-05!GO:0000313;organellar ribosome;1.10485876036298e-05!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.14077739853913e-05!GO:0009152;purine ribonucleotide biosynthetic process;1.32283169226899e-05!GO:0005813;centrosome;1.34313494127143e-05!GO:0006334;nucleosome assembly;1.4245477595214e-05!GO:0048518;positive regulation of biological process;1.42845038585798e-05!GO:0003714;transcription corepressor activity;1.46588725259721e-05!GO:0006164;purine nucleotide biosynthetic process;1.67497695981939e-05!GO:0002376;immune system process;1.68698299111897e-05!GO:0005789;endoplasmic reticulum membrane;1.68698299111897e-05!GO:0045892;negative regulation of transcription, DNA-dependent;1.98473286981047e-05!GO:0030120;vesicle coat;2.05437622535749e-05!GO:0030662;coated vesicle membrane;2.05437622535749e-05!GO:0009966;regulation of signal transduction;2.07951493306547e-05!GO:0009150;purine ribonucleotide metabolic process;2.15054476014494e-05!GO:0006613;cotranslational protein targeting to membrane;2.22040055848246e-05!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;2.25253895554939e-05!GO:0004812;aminoacyl-tRNA ligase activity;2.25253895554939e-05!GO:0016875;ligase activity, forming carbon-oxygen bonds;2.25253895554939e-05!GO:0004298;threonine endopeptidase activity;2.38470237904641e-05!GO:0006163;purine nucleotide metabolic process;2.4555921740848e-05!GO:0006732;coenzyme metabolic process;2.46424071155595e-05!GO:0006402;mRNA catabolic process;2.49149506141288e-05!GO:0015078;hydrogen ion transmembrane transporter activity;2.53198766537422e-05!GO:0000323;lytic vacuole;2.72439040599088e-05!GO:0005764;lysosome;2.72439040599088e-05!GO:0048475;coated membrane;3.03417676665738e-05!GO:0030117;membrane coat;3.03417676665738e-05!GO:0060090;molecular adaptor activity;3.03417676665738e-05!GO:0016469;proton-transporting two-sector ATPase complex;3.14851173061983e-05!GO:0009056;catabolic process;3.74313720976778e-05!GO:0016779;nucleotidyltransferase activity;3.97330929424192e-05!GO:0030695;GTPase regulator activity;4.72006345144327e-05!GO:0043038;amino acid activation;4.86571265193957e-05!GO:0006418;tRNA aminoacylation for protein translation;4.86571265193957e-05!GO:0043039;tRNA aminoacylation;4.86571265193957e-05!GO:0008186;RNA-dependent ATPase activity;4.94400053144696e-05!GO:0005815;microtubule organizing center;5.27189132185802e-05!GO:0007265;Ras protein signal transduction;5.45283902129211e-05!GO:0009142;nucleoside triphosphate biosynthetic process;5.57207640505555e-05!GO:0009201;ribonucleoside triphosphate biosynthetic process;5.57207640505555e-05!GO:0006754;ATP biosynthetic process;5.59415873864706e-05!GO:0006753;nucleoside phosphate metabolic process;5.59415873864706e-05!GO:0045259;proton-transporting ATP synthase complex;5.61457445787231e-05!GO:0008234;cysteine-type peptidase activity;6.57507790507469e-05!GO:0048468;cell development;6.65601399261169e-05!GO:0045333;cellular respiration;6.65601399261169e-05!GO:0032561;guanyl ribonucleotide binding;7.36236081363558e-05!GO:0019001;guanyl nucleotide binding;7.36236081363558e-05!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;7.55597708522594e-05!GO:0015399;primary active transmembrane transporter activity;7.55597708522594e-05!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;8.07669147443264e-05!GO:0001772;immunological synapse;9.35981349386532e-05!GO:0008047;enzyme activator activity;9.43191580223574e-05!GO:0044431;Golgi apparatus part;9.6427211833739e-05!GO:0009199;ribonucleoside triphosphate metabolic process;9.91665845613874e-05!GO:0043623;cellular protein complex assembly;0.00010999223881878!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;0.000111942091476945!GO:0009145;purine nucleoside triphosphate biosynthetic process;0.000111942091476945!GO:0046034;ATP metabolic process;0.000142012390952095!GO:0004004;ATP-dependent RNA helicase activity;0.000147440705496403!GO:0016197;endosome transport;0.000148699028627149!GO:0005667;transcription factor complex;0.000150222782634124!GO:0006612;protein targeting to membrane;0.000171002039367253!GO:0009141;nucleoside triphosphate metabolic process;0.000173152386167219!GO:0005769;early endosome;0.000173653025476574!GO:0003729;mRNA binding;0.000174117077387031!GO:0008654;phospholipid biosynthetic process;0.000179760828588846!GO:0051427;hormone receptor binding;0.000180597945356333!GO:0003690;double-stranded DNA binding;0.000183708695714779!GO:0006310;DNA recombination;0.000186333759355051!GO:0009205;purine ribonucleoside triphosphate metabolic process;0.000188565694797826!GO:0009144;purine nucleoside triphosphate metabolic process;0.000188565694797826!GO:0022415;viral reproductive process;0.000196878514170071!GO:0006950;response to stress;0.000216774520561027!GO:0005083;small GTPase regulator activity;0.000228462895600065!GO:0016301;kinase activity;0.000238615437608431!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000246113477770162!GO:0006099;tricarboxylic acid cycle;0.000246113477770162!GO:0046356;acetyl-CoA catabolic process;0.000246113477770162!GO:0022403;cell cycle phase;0.000277265311743678!GO:0015630;microtubule cytoskeleton;0.000289347818232339!GO:0030384;phosphoinositide metabolic process;0.000290386426910773!GO:0042101;T cell receptor complex;0.000294138288902373!GO:0007005;mitochondrion organization and biogenesis;0.000309678430837967!GO:0015631;tubulin binding;0.000319429807899562!GO:0035257;nuclear hormone receptor binding;0.000322689424669078!GO:0006352;transcription initiation;0.000324424119844846!GO:0051188;cofactor biosynthetic process;0.000324424119844846!GO:0031252;leading edge;0.000353408243257281!GO:0016251;general RNA polymerase II transcription factor activity;0.000364736342382316!GO:0005885;Arp2/3 protein complex;0.000396403749259103!GO:0043492;ATPase activity, coupled to movement of substances;0.000404075335183337!GO:0007050;cell cycle arrest;0.00041450909945601!GO:0005070;SH3/SH2 adaptor activity;0.000437219144207407!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.00046369054028831!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00046369054028831!GO:0019783;small conjugating protein-specific protease activity;0.000495233736119906!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00049947966618979!GO:0005774;vacuolar membrane;0.000514119601314032!GO:0006084;acetyl-CoA metabolic process;0.000531952603164722!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000606930153034818!GO:0015077;monovalent inorganic cation transmembrane transporter activity;0.000628027462630723!GO:0006261;DNA-dependent DNA replication;0.000666963431751619!GO:0006607;NLS-bearing substrate import into nucleus;0.000672530772576642!GO:0004843;ubiquitin-specific protease activity;0.00071368734921962!GO:0046983;protein dimerization activity;0.000770682609976!GO:0051251;positive regulation of lymphocyte activation;0.000776036773871334!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.00079865360786947!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000817226807563928!GO:0005798;Golgi-associated vesicle;0.000840616098329455!GO:0001775;cell activation;0.000840616098329455!GO:0005765;lysosomal membrane;0.000936796439184094!GO:0045941;positive regulation of transcription;0.00094956628857068!GO:0006611;protein export from nucleus;0.000992841783389222!GO:0001819;positive regulation of cytokine production;0.000994871216964956!GO:0009108;coenzyme biosynthetic process;0.00100583935946537!GO:0042802;identical protein binding;0.00102242786829293!GO:0005096;GTPase activator activity;0.00102804687146485!GO:0046822;regulation of nucleocytoplasmic transport;0.00104241544834335!GO:0051090;regulation of transcription factor activity;0.00104540773999301!GO:0051336;regulation of hydrolase activity;0.00105901356855932!GO:0009055;electron carrier activity;0.00110243508208314!GO:0043021;ribonucleoprotein binding;0.00111615002182524!GO:0031902;late endosome membrane;0.00117323781318843!GO:0051338;regulation of transferase activity;0.00126005993302462!GO:0006650;glycerophospholipid metabolic process;0.00130437296765636!GO:0045893;positive regulation of transcription, DNA-dependent;0.00130881810229347!GO:0006468;protein amino acid phosphorylation;0.00132918559205898!GO:0006891;intra-Golgi vesicle-mediated transport;0.00132918559205898!GO:0051789;response to protein stimulus;0.00133290793832837!GO:0006986;response to unfolded protein;0.00133290793832837!GO:0007034;vacuolar transport;0.00138263089918876!GO:0043549;regulation of kinase activity;0.00142184549533432!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00142696535813201!GO:0000139;Golgi membrane;0.00145384500445334!GO:0051223;regulation of protein transport;0.00145384500445334!GO:0044437;vacuolar part;0.00154622446074563!GO:0009109;coenzyme catabolic process;0.00160668237639201!GO:0008287;protein serine/threonine phosphatase complex;0.0016212894971405!GO:0003725;double-stranded RNA binding;0.00164831842034159!GO:0000087;M phase of mitotic cell cycle;0.00165783802905245!GO:0009893;positive regulation of metabolic process;0.00167326508003607!GO:0017091;AU-rich element binding;0.00169188077990358!GO:0050779;RNA destabilization;0.00169188077990358!GO:0000289;poly(A) tail shortening;0.00169188077990358!GO:0004221;ubiquitin thiolesterase activity;0.00170758532775305!GO:0046489;phosphoinositide biosynthetic process;0.00171055463530454!GO:0048471;perinuclear region of cytoplasm;0.00173877223305677!GO:0005637;nuclear inner membrane;0.00178473446675888!GO:0032940;secretion by cell;0.00187880939358796!GO:0030658;transport vesicle membrane;0.00199627949560083!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.00215888409034273!GO:0045859;regulation of protein kinase activity;0.00226168066183855!GO:0006414;translational elongation;0.00228044159217281!GO:0007067;mitosis;0.00228846301589502!GO:0046966;thyroid hormone receptor binding;0.00230527149865818!GO:0051301;cell division;0.00270868904845502!GO:0006405;RNA export from nucleus;0.00273425994518133!GO:0031625;ubiquitin protein ligase binding;0.00275257095779711!GO:0051252;regulation of RNA metabolic process;0.00278502902685465!GO:0003682;chromatin binding;0.00295865352655556!GO:0051329;interphase of mitotic cell cycle;0.00297138655392522!GO:0005741;mitochondrial outer membrane;0.00297138655392522!GO:0019867;outer membrane;0.00297434915697185!GO:0016311;dephosphorylation;0.00306790576615625!GO:0031982;vesicle;0.00306790576615625!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00329052476017989!GO:0006752;group transfer coenzyme metabolic process;0.00330924019832455!GO:0006338;chromatin remodeling;0.00335760809094148!GO:0033673;negative regulation of kinase activity;0.00344951607611056!GO:0006469;negative regulation of protein kinase activity;0.00344951607611056!GO:0046474;glycerophospholipid biosynthetic process;0.00350362130944147!GO:0051187;cofactor catabolic process;0.00350874699735891!GO:0031968;organelle outer membrane;0.00351261094374855!GO:0031072;heat shock protein binding;0.0036308816100945!GO:0016584;nucleosome positioning;0.00370548683121388!GO:0003678;DNA helicase activity;0.00373171561837517!GO:0006919;caspase activation;0.00373171561837517!GO:0030097;hemopoiesis;0.00386816993341349!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;0.003887561805329!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00390667327232505!GO:0006955;immune response;0.00405038301174039!GO:0008017;microtubule binding;0.00419545153292129!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00437821739072103!GO:0030518;steroid hormone receptor signaling pathway;0.00444570642488064!GO:0030660;Golgi-associated vesicle membrane;0.0044921741648502!GO:0016585;chromatin remodeling complex;0.00461600900728631!GO:0048500;signal recognition particle;0.00463660564640844!GO:0018193;peptidyl-amino acid modification;0.00463817015188023!GO:0051325;interphase;0.00465654905566008!GO:0051348;negative regulation of transferase activity;0.00465672206467983!GO:0006984;ER-nuclear signaling pathway;0.00489589920856521!GO:0042287;MHC protein binding;0.00490145023020514!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00494163132028739!GO:0043087;regulation of GTPase activity;0.00497046310995551!GO:0002757;immune response-activating signal transduction;0.0050757320132432!GO:0005057;receptor signaling protein activity;0.00507595055027543!GO:0005669;transcription factor TFIID complex;0.00531205186205529!GO:0008022;protein C-terminus binding;0.00531358317876605!GO:0043488;regulation of mRNA stability;0.00531358317876605!GO:0043487;regulation of RNA stability;0.00531358317876605!GO:0051092;activation of NF-kappaB transcription factor;0.0053253820847947!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.00544502238675242!GO:0003899;DNA-directed RNA polymerase activity;0.00548166161089441!GO:0008139;nuclear localization sequence binding;0.00558592323820906!GO:0030258;lipid modification;0.00575693346867711!GO:0030521;androgen receptor signaling pathway;0.00609064829504474!GO:0045045;secretory pathway;0.00612516954395278!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00628614436371968!GO:0005048;signal sequence binding;0.00641185825081673!GO:0000209;protein polyubiquitination;0.00652291304015511!GO:0006383;transcription from RNA polymerase III promoter;0.00664630397869198!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00665035962347008!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00665035962347008!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00665035962347008!GO:0019058;viral infectious cycle;0.00667481511105298!GO:0002429;immune response-activating cell surface receptor signaling pathway;0.00670812245630535!GO:0030217;T cell differentiation;0.00683379536994847!GO:0046467;membrane lipid biosynthetic process;0.00685963961685954!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00693522734564612!GO:0051052;regulation of DNA metabolic process;0.0070199586359695!GO:0019843;rRNA binding;0.00711077865937614!GO:0016791;phosphoric monoester hydrolase activity;0.00720414982433454!GO:0004715;non-membrane spanning protein tyrosine kinase activity;0.00722231177261384!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00753347352059788!GO:0045047;protein targeting to ER;0.00753347352059788!GO:0043280;positive regulation of caspase activity;0.00753614796410466!GO:0003746;translation elongation factor activity;0.00763563990002685!GO:0032200;telomere organization and biogenesis;0.00769286350843992!GO:0000723;telomere maintenance;0.00769286350843992!GO:0019079;viral genome replication;0.00783094289095352!GO:0005684;U2-dependent spliceosome;0.00789465940985309!GO:0043281;regulation of caspase activity;0.007915724315031!GO:0005657;replication fork;0.00797220495480215!GO:0030127;COPII vesicle coat;0.00799416510068971!GO:0012507;ER to Golgi transport vesicle membrane;0.00799416510068971!GO:0031410;cytoplasmic vesicle;0.00800623657699866!GO:0008312;7S RNA binding;0.00801067108248148!GO:0002520;immune system development;0.00802003114039324!GO:0051098;regulation of binding;0.00807098591421627!GO:0044452;nucleolar part;0.00833900091041629!GO:0019901;protein kinase binding;0.00838159789255441!GO:0051059;NF-kappaB binding;0.0085101958910991!GO:0030968;unfolded protein response;0.00870776004714841!GO:0006302;double-strand break repair;0.00888261366429517!GO:0031325;positive regulation of cellular metabolic process;0.00924075544529004!GO:0000118;histone deacetylase complex;0.00936142039938402!GO:0007041;lysosomal transport;0.00956241257442038!GO:0004428;inositol or phosphatidylinositol kinase activity;0.00964284089382695!GO:0031901;early endosome membrane;0.00978052908105063!GO:0016790;thiolester hydrolase activity;0.00986119611155519!GO:0008168;methyltransferase activity;0.00988807363374489!GO:0008637;apoptotic mitochondrial changes;0.00990231181129875!GO:0016605;PML body;0.0101384433908774!GO:0050865;regulation of cell activation;0.0101457344225965!GO:0002764;immune response-regulating signal transduction;0.0101557007887759!GO:0006376;mRNA splice site selection;0.0107566193166397!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0107566193166397!GO:0016741;transferase activity, transferring one-carbon groups;0.0107723206166197!GO:0033157;regulation of intracellular protein transport;0.0108744875246957!GO:0042306;regulation of protein import into nucleus;0.0108744875246957!GO:0000059;protein import into nucleus, docking;0.0109592667408048!GO:0003711;transcription elongation regulator activity;0.0111818004330662!GO:0019904;protein domain specific binding;0.0112298248770889!GO:0033116;ER-Golgi intermediate compartment membrane;0.0113317729140782!GO:0000279;M phase;0.0113519287031195!GO:0051249;regulation of lymphocyte activation;0.0113651956021833!GO:0004722;protein serine/threonine phosphatase activity;0.0114334742562652!GO:0045603;positive regulation of endothelial cell differentiation;0.0115679907259724!GO:0043414;biopolymer methylation;0.0116654534882163!GO:0030522;intracellular receptor-mediated signaling pathway;0.0119659180701861!GO:0002521;leukocyte differentiation;0.0122032861307086!GO:0031988;membrane-bound vesicle;0.0125162357243767!GO:0004527;exonuclease activity;0.0127748738090462!GO:0051235;maintenance of localization;0.0128337132919198!GO:0030134;ER to Golgi transport vesicle;0.013064053418392!GO:0000082;G1/S transition of mitotic cell cycle;0.0131357255479638!GO:0051539;4 iron, 4 sulfur cluster binding;0.0133415549843028!GO:0015923;mannosidase activity;0.0133742772781432!GO:0001726;ruffle;0.0133831524026921!GO:0008624;induction of apoptosis by extracellular signals;0.0136523443457767!GO:0048487;beta-tubulin binding;0.0136543012364132!GO:0002768;immune response-regulating cell surface receptor signaling pathway;0.0137050839213467!GO:0005819;spindle;0.0137817097359015!GO:0043433;negative regulation of transcription factor activity;0.0137921493191206!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0139721298119093!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0141746288055162!GO:0006818;hydrogen transport;0.0144387011448091!GO:0000049;tRNA binding;0.0144507607295012!GO:0047485;protein N-terminus binding;0.0145882090471478!GO:0050871;positive regulation of B cell activation;0.0147338701816564!GO:0004721;phosphoprotein phosphatase activity;0.0157120741145179!GO:0046854;phosphoinositide phosphorylation;0.015904436445988!GO:0022411;cellular component disassembly;0.0159287677593894!GO:0000119;mediator complex;0.0159479417283688!GO:0006470;protein amino acid dephosphorylation;0.0160282122300929!GO:0015992;proton transport;0.0160392138997874!GO:0030118;clathrin coat;0.0160392138997874!GO:0004672;protein kinase activity;0.0162330342100134!GO:0000060;protein import into nucleus, translocation;0.0162959997473585!GO:0005521;lamin binding;0.0163663337202592!GO:0046578;regulation of Ras protein signal transduction;0.0164461816302358!GO:0019210;kinase inhibitor activity;0.0169654510757708!GO:0040029;regulation of gene expression, epigenetic;0.0169654510757708!GO:0003684;damaged DNA binding;0.0171734987024873!GO:0031098;stress-activated protein kinase signaling pathway;0.0172396739319413!GO:0003950;NAD+ ADP-ribosyltransferase activity;0.0176241729739255!GO:0050870;positive regulation of T cell activation;0.0176274833385671!GO:0000786;nucleosome;0.0177114032782291!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0177515033995049!GO:0032318;regulation of Ras GTPase activity;0.0178261333315091!GO:0007006;mitochondrial membrane organization and biogenesis;0.0194877699047288!GO:0045069;regulation of viral genome replication;0.0196005877301893!GO:0046834;lipid phosphorylation;0.0197294807940734!GO:0043407;negative regulation of MAP kinase activity;0.0197777701390441!GO:0030867;rough endoplasmic reticulum membrane;0.0205012498619121!GO:0008276;protein methyltransferase activity;0.020567860256506!GO:0004860;protein kinase inhibitor activity;0.0207657611913874!GO:0043022;ribosome binding;0.02135968234246!GO:0005762;mitochondrial large ribosomal subunit;0.0215394561889079!GO:0000315;organellar large ribosomal subunit;0.0215394561889079!GO:0006661;phosphatidylinositol biosynthetic process;0.0217217764283381!GO:0009117;nucleotide metabolic process;0.0217436401853839!GO:0000781;chromosome, telomeric region;0.0218196842105863!GO:0016788;hydrolase activity, acting on ester bonds;0.0219893223557184!GO:0051091;positive regulation of transcription factor activity;0.0219948648583864!GO:0043681;protein import into mitochondrion;0.0222975263722513!GO:0050811;GABA receptor binding;0.0226294438804786!GO:0016023;cytoplasmic membrane-bound vesicle;0.0238700261867866!GO:0032259;methylation;0.0240286660007939!GO:0005791;rough endoplasmic reticulum;0.0240506280039066!GO:0001667;ameboidal cell migration;0.0245878440349491!GO:0032027;myosin light chain binding;0.0245878440349491!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.0248988710146187!GO:0043621;protein self-association;0.0252006721109772!GO:0006672;ceramide metabolic process;0.0252348372438952!GO:0042990;regulation of transcription factor import into nucleus;0.0256689621393345!GO:0042991;transcription factor import into nucleus;0.0256689621393345!GO:0005869;dynactin complex;0.0262458317944611!GO:0005099;Ras GTPase activator activity;0.0267851958888237!GO:0006289;nucleotide-excision repair;0.0268264562596627!GO:0003702;RNA polymerase II transcription factor activity;0.0276673579666871!GO:0045185;maintenance of protein localization;0.0281454315622247!GO:0030433;ER-associated protein catabolic process;0.028208139755863!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.028208139755863!GO:0016566;specific transcriptional repressor activity;0.0282412836952641!GO:0007004;telomere maintenance via telomerase;0.0283903981730313!GO:0019900;kinase binding;0.0283903981730313!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.028645237221531!GO:0032508;DNA duplex unwinding;0.0288016346664333!GO:0032392;DNA geometric change;0.0288016346664333!GO:0006354;RNA elongation;0.0288058026210861!GO:0045058;T cell selection;0.0288718472720713!GO:0046519;sphingoid metabolic process;0.0293892620388681!GO:0031461;cullin-RING ubiquitin ligase complex;0.0298432006042122!GO:0048534;hemopoietic or lymphoid organ development;0.0298932172649317!GO:0006497;protein amino acid lipidation;0.0300460208490616!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0301625733265763!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0301625733265763!GO:0051087;chaperone binding;0.0306128158229368!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0309728071759053!GO:0016044;membrane organization and biogenesis;0.0311536219194736!GO:0004518;nuclease activity;0.0317309058415994!GO:0006643;membrane lipid metabolic process;0.0317309058415994!GO:0045637;regulation of myeloid cell differentiation;0.0317547019367179!GO:0050851;antigen receptor-mediated signaling pathway;0.0318168550526194!GO:0042608;T cell receptor binding;0.0319623499720106!GO:0004402;histone acetyltransferase activity;0.0322475815890337!GO:0004468;lysine N-acetyltransferase activity;0.0322475815890337!GO:0007254;JNK cascade;0.032391731323153!GO:0006914;autophagy;0.0324642268478237!GO:0008097;5S rRNA binding;0.032594482595842!GO:0030099;myeloid cell differentiation;0.0327619980762348!GO:0002440;production of molecular mediator of immune response;0.0329547320192679!GO:0016279;protein-lysine N-methyltransferase activity;0.0330839928832425!GO:0018024;histone-lysine N-methyltransferase activity;0.0330839928832425!GO:0016278;lysine N-methyltransferase activity;0.0330839928832425!GO:0007259;JAK-STAT cascade;0.0332324404003471!GO:0008629;induction of apoptosis by intracellular signals;0.03354460046837!GO:0045792;negative regulation of cell size;0.03354460046837!GO:0032386;regulation of intracellular transport;0.0335536516435296!GO:0016569;covalent chromatin modification;0.0337689361779138!GO:0046979;TAP2 binding;0.0338219297951195!GO:0046977;TAP binding;0.0338219297951195!GO:0046978;TAP1 binding;0.0338219297951195!GO:0035026;leading edge cell differentiation;0.0341405537106895!GO:0035035;histone acetyltransferase binding;0.0341802766256751!GO:0045736;negative regulation of cyclin-dependent protein kinase activity;0.034290592264779!GO:0033549;MAP kinase phosphatase activity;0.0350949227294398!GO:0017017;MAP kinase tyrosine/serine/threonine phosphatase activity;0.0350949227294398!GO:0001817;regulation of cytokine production;0.0355957724014892!GO:0050852;T cell receptor signaling pathway;0.035749799241965!GO:0000188;inactivation of MAPK activity;0.0362150434626558!GO:0030374;ligand-dependent nuclear receptor transcription coactivator activity;0.0363873123474193!GO:0016859;cis-trans isomerase activity;0.0365543659744118!GO:0045454;cell redox homeostasis;0.0365543659744118!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0367335378536553!GO:0004003;ATP-dependent DNA helicase activity;0.0371560065738228!GO:0030098;lymphocyte differentiation;0.0371625556055452!GO:0008601;protein phosphatase type 2A regulator activity;0.0373012958179828!GO:0006926;virus-infected cell apoptosis;0.0376143446355201!GO:0000287;magnesium ion binding;0.0379994147233524!GO:0046426;negative regulation of JAK-STAT cascade;0.0383250184493426!GO:0022406;membrane docking;0.0385001669310892!GO:0048278;vesicle docking;0.0385001669310892!GO:0045926;negative regulation of growth;0.0385603133412391!GO:0000303;response to superoxide;0.0391086100243122!GO:0004197;cysteine-type endopeptidase activity;0.0394967310275827!GO:0030036;actin cytoskeleton organization and biogenesis;0.0396578759876894!GO:0051056;regulation of small GTPase mediated signal transduction;0.0398214243360656!GO:0016570;histone modification;0.0398868617445817!GO:0022890;inorganic cation transmembrane transporter activity;0.0398868617445817!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0398868617445817!GO:0008033;tRNA processing;0.0398868617445817!GO:0004177;aminopeptidase activity;0.040008147212785!GO:0030663;COPI coated vesicle membrane;0.040008147212785!GO:0030126;COPI vesicle coat;0.040008147212785!GO:0016272;prefoldin complex;0.0400418490050267!GO:0006506;GPI anchor biosynthetic process;0.0405195151730107!GO:0030137;COPI-coated vesicle;0.0416399451600997!GO:0033367;protein localization in mast cell secretory granule;0.0417035886302124!GO:0033365;protein localization in organelle;0.0417035886302124!GO:0033371;T cell secretory granule organization and biogenesis;0.0417035886302124!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.0417035886302124!GO:0033375;protease localization in T cell secretory granule;0.0417035886302124!GO:0042629;mast cell granule;0.0417035886302124!GO:0033377;maintenance of protein localization in T cell secretory granule;0.0417035886302124!GO:0033364;mast cell secretory granule organization and biogenesis;0.0417035886302124!GO:0033380;granzyme B localization in T cell secretory granule;0.0417035886302124!GO:0033379;maintenance of protease localization in T cell secretory granule;0.0417035886302124!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.0417035886302124!GO:0033368;protease localization in mast cell secretory granule;0.0417035886302124!GO:0033366;protein localization in secretory granule;0.0417035886302124!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.0417035886302124!GO:0033374;protein localization in T cell secretory granule;0.0417035886302124!GO:0000339;RNA cap binding;0.041930330531974!GO:0002822;regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains.;0.041953525293389!GO:0002819;regulation of adaptive immune response;0.041953525293389!GO:0030833;regulation of actin filament polymerization;0.0419890427659462!GO:0030308;negative regulation of cell growth;0.04203881382561!GO:0019220;regulation of phosphate metabolic process;0.0420898332244639!GO:0051174;regulation of phosphorus metabolic process;0.0420898332244639!GO:0048002;antigen processing and presentation of peptide antigen;0.043009660674317!GO:0045746;negative regulation of Notch signaling pathway;0.0431310452341617!GO:0006406;mRNA export from nucleus;0.0432100389533039!GO:0008094;DNA-dependent ATPase activity;0.0432491869125742!GO:0000738;DNA catabolic process, exonucleolytic;0.0433048949313213!GO:0030880;RNA polymerase complex;0.0433673589613647!GO:0019883;antigen processing and presentation of endogenous antigen;0.0433771751323095!GO:0032507;maintenance of cellular protein localization;0.0433771751323095!GO:0050863;regulation of T cell activation;0.0436532166840514!GO:0042532;negative regulation of tyrosine phosphorylation of STAT protein;0.0437660726269131!GO:0042518;negative regulation of tyrosine phosphorylation of Stat3 protein;0.0437660726269131!GO:0050732;negative regulation of peptidyl-tyrosine phosphorylation;0.0437660726269131!GO:0006904;vesicle docking during exocytosis;0.0438906521484151!GO:0000288;mRNA catabolic process, deadenylation-dependent decay;0.0441325618369068!GO:0035258;steroid hormone receptor binding;0.0441325618369068!GO:0009299;mRNA transcription;0.0449167712169101!GO:0015980;energy derivation by oxidation of organic compounds;0.0450896880032699!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0457715884478623!GO:0004576;oligosaccharyl transferase activity;0.0459269255923119!GO:0006595;polyamine metabolic process;0.0459438348822232!GO:0030176;integral to endoplasmic reticulum membrane;0.0459438348822232!GO:0000776;kinetochore;0.0464812491246266!GO:0005062;hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity;0.0480882315623278!GO:0000314;organellar small ribosomal subunit;0.0480882315623278!GO:0005763;mitochondrial small ribosomal subunit;0.0480882315623278!GO:0008180;signalosome;0.0480882315623278!GO:0030041;actin filament polymerization;0.0490954675659751!GO:0006505;GPI anchor metabolic process;0.0492166765397245!GO:0001909;leukocyte mediated cytotoxicity;0.0494914027072345!GO:0005095;GTPase inhibitor activity;0.0499263023136561 | |||
|sample_id=11230 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=blood | |||
|top_motifs=RORA:4.54284170619;PAX3,7:3.87128400184;RUNX1..3:3.71473833468;CREB1:3.62516220857;ATF5_CREB3:3.50083091249;ATF4:3.42713696972;RFX2..5_RFXANK_RFXAP:3.25301354337;NFKB1_REL_RELA:2.98368455824;FOXO1,3,4:2.97329513557;FOX{D1,D2}:2.96774058542;T:2.92923002669;ELF1,2,4:2.90416625732;ETS1,2:2.74113497615;DMAP1_NCOR{1,2}_SMARC:2.65922060281;PAX2:2.59992724355;BPTF:2.56386926169;FOXN1:2.2906723776;TBX4,5:2.26163588883;RFX1:2.12691290293;TGIF1:2.11851634851;SPI1:2.11154620654;JUN:2.05658330079;FOX{F1,F2,J1}:1.90589620056;TLX2:1.80840314096;IRF1,2:1.77072984459;HMX1:1.76261447811;SPIB:1.74535098932;ATF2:1.6324684267;ATF6:1.58615782935;PITX1..3:1.40886017792;FOXP1:1.36483374814;FOX{I1,J2}:1.32814420657;NKX2-1,4:1.29923881037;HIF1A:1.2253645613;EP300:1.17991784776;FOSL2:1.16275434893;NFATC1..3:1.11604151996;FOS_FOS{B,L1}_JUN{B,D}:1.02219781072;HMGA1,2:0.967763875476;ZBTB16:0.966759448686;NANOG{mouse}:0.95500016144;BREu{core}:0.945372635986;IRF7:0.842114763137;LEF1_TCF7_TCF7L1,2:0.816278813916;PAX6:0.813257795089;BACH2:0.708037819354;IKZF2:0.696150384723;SREBF1,2:0.679652173062;FOXP3:0.667776590647;MAFB:0.667656631755;SOX2:0.659726805125;ZNF384:0.648107740381;NFIL3:0.640763281488;NFE2:0.639778752698;ELK1,4_GABP{A,B1}:0.635486765897;MYB:0.594802653735;SMAD1..7,9:0.561950372171;PAX4:0.522977413836;CDX1,2,4:0.448178264478;GATA6:0.365812077416;EGR1..3:0.349282013384;NKX6-1,2:0.330759635103;TFDP1:0.308253718498;STAT2,4,6:0.295850038061;CEBPA,B_DDIT3:0.235274466469;NFE2L1:0.18738506401;HLF:0.158961422958;RBPJ:0.14711791106;MYFfamily:0.111141622503;PDX1:0.111032405207;RREB1:0.0876750440215;HBP1_HMGB_SSRP1_UBTF:0.0861414977178;NFE2L2:0.0817217047857;NFY{A,B,C}:0.0331267686222;AHR_ARNT_ARNT2:0.0203089447346;PPARG:0.0174250194827;RXRA_VDR{dimer}:0.0120295822754;NANOG:-0.022531992828;GCM1,2:-0.110943428422;HOX{A6,A7,B6,B7}:-0.145303671584;FOXQ1:-0.221767937621;SOX5:-0.238650029298;STAT1,3:-0.24274418762;CRX:-0.244702775078;POU2F1..3:-0.329076463613;FOXL1:-0.335337834385;E2F1..5:-0.351941404592;TOPORS:-0.369867891346;GLI1..3:-0.433126127411;NRF1:-0.433921094613;AIRE:-0.434207578494;ZEB1:-0.447630929545;HOXA9_MEIS1:-0.450157459846;PBX1:-0.450483762171;ZFP161:-0.451184715643;SNAI1..3:-0.491318205558;PRRX1,2:-0.498114854138;MTE{core}:-0.513796188196;MED-1{core}:-0.517536215845;MYOD1:-0.534453168445;NKX3-1:-0.577913079392;CUX2:-0.581062184293;HSF1,2:-0.584710908721;SRF:-0.588514604228;XBP1:-0.604316252471;TAL1_TCF{3,4,12}:-0.6073801045;NFIX:-0.613113118696;HES1:-0.621327322803;PAX5:-0.642335251158;TFAP4:-0.644847746924;FOXD3:-0.648100762235;PATZ1:-0.650861953519;TFAP2B:-0.652754611785;NHLH1,2:-0.705515720092;DBP:-0.719023979973;MZF1:-0.761415166515;STAT5{A,B}:-0.765598314311;SPZ1:-0.77889311453;EVI1:-0.779799938546;HNF1A:-0.794758217689;HNF4A_NR2F1,2:-0.823075124417;SOX{8,9,10}:-0.839539787292;MTF1:-0.84203779726;NR5A1,2:-0.847074636953;NR1H4:-0.850410549119;MAZ:-0.85938291639;REST:-0.883811313835;bHLH_family:-0.895111515282;MEF2{A,B,C,D}:-0.89972933878;TFCP2:-0.908010895805;OCT4_SOX2{dimer}:-0.911938379544;GATA4:-0.912460044204;YY1:-0.944839484601;SP1:-0.987667043155;AR:-0.990852345062;LMO2:-1.00009145781;ZNF148:-1.01055227903;RXR{A,B,G}_{NR1H2,PPAR}dimers:-1.01522386525;FOXA2:-1.01740249685;LHX3,4:-1.02269290169;TFAP2{A,C}:-1.02788129312;ZBTB6:-1.0455277388;ALX4:-1.07670335348;ESRRA:-1.12832431452;FOXM1:-1.13953455585;HIC1:-1.18437005189;ZNF143:-1.20555918128;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-1.22976466061;ZNF423:-1.25486634992;ZNF238:-1.2746573615;NKX2-2,8:-1.2977149184;MYBL2:-1.3049857755;ZIC1..3:-1.33400263286;VSX1,2:-1.35562411238;ALX1:-1.36791881712;POU5F1:-1.37448755473;TBP:-1.376184528;GFI1:-1.3874997917;PAX8:-1.47210020173;XCPE1{core}:-1.48414775416;RXR{A,B,G}:-1.48633455545;SOX17:-1.58363368953;HOX{A5,B5}:-1.586818244;TP53:-1.59178712531;CDC5L:-1.6512822012;GTF2I:-1.73812675455;GTF2A1,2:-1.80524008862;GFI1B:-1.80774554157;EN1,2:-1.8630579372;TEAD1:-1.88908533263;ARID5B:-1.88913968363;NKX2-3_NKX2-5:-1.88995981251;HAND1,2:-1.91527620615;TLX1..3_NFIC{dimer}:-1.91581302623;ESR1:-1.95678197733;GZF1:-1.95779883154;POU1F1:-1.9578916231;UFEwm:-1.96608240252;PRDM1:-2.02268532768;TEF:-2.02479109574;POU6F1:-2.04696487437;HOX{A4,D4}:-2.15369130756;POU3F1..4:-2.18809074293;IKZF1:-2.38086878413;EBF1:-2.40546640124;KLF4:-2.46571274922;ADNP_IRX_SIX_ZHX:-2.47400756013;NKX3-2:-2.63544542823;PAX1,9:-2.72343148039;NR6A1:-2.72551060221;NR3C1:-2.91884518532;ONECUT1,2:-3.07519189978 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11230-116C6;search_select_hide=table117:FF:11230-116C6 | |||
}} | }} |
Latest revision as of 16:26, 3 June 2020
Name: | Natural Killer Cells, donor1 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs10859 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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RNA-Seq Accession numbers | ||||||||||||||||||||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs10859
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs10859
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.904 |
10 | 10 | 0.0169 |
100 | 100 | 0.792 |
101 | 101 | 0.56 |
102 | 102 | 0.992 |
103 | 103 | 0.798 |
104 | 104 | 0.694 |
105 | 105 | 0.402 |
106 | 106 | 0.25 |
107 | 107 | 0.038 |
108 | 108 | 0.36 |
109 | 109 | 0.857 |
11 | 11 | 0.891 |
110 | 110 | 0.36 |
111 | 111 | 0.536 |
112 | 112 | 0.896 |
113 | 113 | 0.277 |
114 | 114 | 0.934 |
115 | 115 | 0.215 |
116 | 116 | 0.112 |
117 | 117 | 0.0134 |
118 | 118 | 0.469 |
119 | 119 | 0.333 |
12 | 12 | 0.371 |
120 | 120 | 0.192 |
121 | 121 | 0.392 |
122 | 122 | 0.648 |
123 | 123 | 0.00365 |
124 | 124 | 0.944 |
125 | 125 | 0.593 |
126 | 126 | 0.442 |
127 | 127 | 0.764 |
128 | 128 | 0.884 |
129 | 129 | 0.252 |
13 | 13 | 0.5 |
130 | 130 | 0.262 |
131 | 131 | 0.273 |
132 | 132 | 0.0845 |
133 | 133 | 0.471 |
134 | 134 | 0.831 |
135 | 135 | 0.679 |
136 | 136 | 0.874 |
137 | 137 | 0.0231 |
138 | 138 | 0.479 |
139 | 139 | 0.18 |
14 | 14 | 0.475 |
140 | 140 | 0.733 |
141 | 141 | 0.875 |
142 | 142 | 0.519 |
143 | 143 | 0.00909 |
144 | 144 | 0.879 |
145 | 145 | 0.543 |
146 | 146 | 0.551 |
147 | 147 | 0.0226 |
148 | 148 | 0.542 |
149 | 149 | 0.121 |
15 | 15 | 0.301 |
150 | 150 | 0.991 |
151 | 151 | 0.443 |
152 | 152 | 0.841 |
153 | 153 | 0.893 |
154 | 154 | 0.249 |
155 | 155 | 0.101 |
156 | 156 | 0.694 |
157 | 157 | 0.687 |
158 | 158 | 0.0133 |
159 | 159 | 0.609 |
16 | 16 | 0.287 |
160 | 160 | 0.0307 |
161 | 161 | 0.924 |
162 | 162 | 0.00736 |
163 | 163 | 0.897 |
164 | 164 | 0.173 |
165 | 165 | 0.632 |
166 | 166 | 0.572 |
167 | 167 | 0.214 |
168 | 168 | 0.719 |
169 | 169 | 0.211 |
17 | 17 | 0.708 |
18 | 18 | 0.846 |
19 | 19 | 0.0298 |
2 | 2 | 0.139 |
20 | 20 | 0.178 |
21 | 21 | 0.551 |
22 | 22 | 0.314 |
23 | 23 | 0.994 |
24 | 24 | 0.776 |
25 | 25 | 0.189 |
26 | 26 | 0.763 |
27 | 27 | 0.489 |
28 | 28 | 0.394 |
29 | 29 | 0.128 |
3 | 3 | 0.729 |
30 | 30 | 0.0921 |
31 | 31 | 0.632 |
32 | 32 | 0.00241 |
33 | 33 | 0.365 |
34 | 34 | 0.518 |
35 | 35 | 0.431 |
36 | 36 | 0.0986 |
37 | 37 | 0.498 |
38 | 38 | 0.709 |
39 | 39 | 0.478 |
4 | 4 | 0.765 |
40 | 40 | 0.919 |
41 | 41 | 0.0387 |
42 | 42 | 0.544 |
43 | 43 | 0.445 |
44 | 44 | 0.492 |
45 | 45 | 0.163 |
46 | 46 | 0.911 |
47 | 47 | 0.963 |
48 | 48 | 0.864 |
49 | 49 | 0.285 |
5 | 5 | 0.482 |
50 | 50 | 0.523 |
51 | 51 | 0.922 |
52 | 52 | 0.869 |
53 | 53 | 0.357 |
54 | 54 | 0.968 |
55 | 55 | 0.313 |
56 | 56 | 0.776 |
57 | 57 | 0.614 |
58 | 58 | 0.206 |
59 | 59 | 0.189 |
6 | 6 | 0.774 |
60 | 60 | 0.521 |
61 | 61 | 0.326 |
62 | 62 | 0.335 |
63 | 63 | 0.637 |
64 | 64 | 0.912 |
65 | 65 | 0.561 |
66 | 66 | 0.447 |
67 | 67 | 0.615 |
68 | 68 | 0.606 |
69 | 69 | 0.576 |
7 | 7 | 0.559 |
70 | 70 | 0.28 |
71 | 71 | 0.24 |
72 | 72 | 0.24 |
73 | 73 | 0.528 |
74 | 74 | 0.952 |
75 | 75 | 0.0731 |
76 | 76 | 0.132 |
77 | 77 | 0.00315 |
78 | 78 | 0.983 |
79 | 79 | 0.893 |
8 | 8 | 0.215 |
80 | 80 | 0.00856 |
81 | 81 | 0.971 |
82 | 82 | 0.667 |
83 | 83 | 0.59 |
84 | 84 | 0.147 |
85 | 85 | 0.761 |
86 | 86 | 0.0495 |
87 | 87 | 0.894 |
88 | 88 | 0.725 |
89 | 89 | 0.00789 |
9 | 9 | 0.965 |
90 | 90 | 0.833 |
91 | 91 | 0.703 |
92 | 92 | 0.586 |
93 | 93 | 0.656 |
94 | 94 | 0.222 |
95 | 95 | 0.289 |
96 | 96 | 0.934 |
97 | 97 | 0.559 |
98 | 98 | 0.597 |
99 | 99 | 4.34782e-7 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs10859
FANTOM5 (FF) ontology
Direct parent terms
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0002371 (somatic cell)
0000542 (lymphocyte)
0000219 (motile cell)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0002242 (nucleate cell)
0000255 (eukaryotic cell)
0000623 (natural killer cell)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)
0000119 (human natural killer cell sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)
CL:0000051 (common lymphoid progenitor)