FFCP PHASE1:Hg19::chr22:30653345..30653353,-: Difference between revisions
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{{FFCP | {{FFCP|DPIdataset=robustDPI|EntrezGene=NA|GencodeV16b_All_Build2_RSEM10_CPAT_consensus=no_gencodeV16_or_build2_transcript|HGNC=NA|TSSclassifier=N|UniProt=NA|association_with_transcript=NA|coexpression_cluster_id=C1262|description=CAGE_peak_at_chr22:30653345..30653353,-|id=chr22:30653345..30653353,-|ontology_enrichment_celltype=CL:1000497!2.22e-16!18;CL:0002518!2.22e-16!18;CL:1000449!2.88e-15!16;CL:1000507!1.67e-13!12;CL:1000494!1.67e-13!12;CL:0000066!3.52e-13!254;CL:0002149!1.85e-11!6;CL:0002255!1.85e-11!6;CL:0002681!1.84e-09!13;CL:0002584!1.84e-09!13|ontology_enrichment_celltype_v019=CL:1000497;9.88e-21;17!CL:0002518;9.88e-21;17!CL:1000507;1.73e-18;10!CL:1000494;1.73e-18;10!CL:1000449;2.60e-17;15!CL:0002681;6.05e-10;12!CL:0002584;6.05e-10;12!CL:1001319;1.42e-08;1!CL:1000600;1.42e-08;1|ontology_enrichment_celltype_v019_2=CL:1000497,8.52e-21,17;CL:0002518,8.52e-21,17;CL:1000507,1.50e-18,10;CL:1000494,1.50e-18,10;CL:1000449,2.25e-17,15;CL:0002681,5.64e-10,12;CL:0002584,5.64e-10,12;CL:1001319,1.22e-08,1;CL:1000600,1.22e-08,1|ontology_enrichment_development_v019=|ontology_enrichment_disease=DOID:0050687!4.27e-20!143;DOID:305!1.82e-19!106;DOID:299!3.47e-15!25;DOID:162!6.69e-15!235;DOID:14566!2.48e-14!239;DOID:3001!1.85e-11!6;DOID:0050686!6.29e-07!137;DOID:4468!8.10e-07!2|ontology_enrichment_disease_v019=DOID:4468;5.40e-16;2!DOID:1115;5.77e-09;20!DOID:3111;7.17e-09;1!DOID:3603;7.17e-09;1!DOID:299;2.39e-07;25!DOID:3908;7.15e-07;5|ontology_enrichment_disease_v019_2=DOID:4468,5.83e-16,2;DOID:0050687,3.01e-10,143;DOID:3111,6.65e-09,1;DOID:3603,6.65e-09,1;DOID:1115,7.35e-09,20;DOID:299,2.26e-07,25;DOID:3908,5.73e-07,5|ontology_enrichment_uberon=UBERON:0000058!3.26e-17!26;UBERON:0004211!2.88e-15!16;UBERON:0001285!2.88e-15!16;UBERON:0007684!2.88e-15!16;UBERON:0003220!2.88e-15!16;UBERON:0004208!2.88e-15!16;UBERON:0006555!3.11e-14!17;UBERON:0005103!3.11e-14!17;UBERON:0000083!3.11e-14!17;UBERON:0009201!3.11e-14!17;UBERON:0004819!3.11e-14!17;UBERON:0006553!3.11e-14!17;UBERON:0003074!3.11e-14!17;UBERON:0003060!3.11e-14!17;UBERON:0002113!4.16e-14!27;UBERON:0003918!4.16e-14!27;UBERON:0005095!4.16e-14!27;UBERON:0007687!4.16e-14!27;UBERON:0003886!1.35e-13!63;UBERON:0009773!1.67e-13!12;UBERON:0001231!1.67e-13!12;UBERON:0004810!1.67e-13!12;UBERON:0000489!2.04e-13!32;UBERON:0005177!2.23e-13!107;UBERON:0000080!2.57e-13!18;UBERON:0002120!2.57e-13!18;UBERON:0004875!2.57e-13!18;UBERON:0005721!2.57e-13!18;UBERON:0005754!2.57e-13!18;UBERON:0007297!2.57e-13!18;UBERON:0006554!7.48e-12!44;UBERON:0004876!9.28e-12!20;UBERON:0002553!1.12e-11!70;UBERON:0001008!1.69e-11!45;UBERON:0003887!4.30e-11!21;UBERON:0003064!4.62e-11!37;UBERON:0002075!8.49e-11!18;UBERON:0000464!9.11e-11!104;UBERON:0000466!2.51e-10!126;UBERON:0002114!6.45e-10!12;UBERON:0001264!9.75e-10!10;UBERON:0003922!9.75e-10!10;UBERON:0003923!9.75e-10!10;UBERON:0003924!9.75e-10!10;UBERON:0003921!9.75e-10!10;UBERON:0005172!1.22e-09!55;UBERON:0005173!1.22e-09!55;UBERON:0001851!1.30e-09!16;UBERON:0001225!1.84e-09!13;UBERON:0008987!1.84e-09!13;UBERON:0002294!5.31e-09!7;UBERON:0001173!5.31e-09!7;UBERON:0004912!5.31e-09!7;UBERON:0000353!8.23e-09!17;UBERON:0001045!8.98e-09!11;UBERON:0002108!1.98e-08!14;UBERON:0002417!2.74e-08!61;UBERON:0000916!2.74e-08!61;UBERON:0003104!6.32e-08!238;UBERON:0009142!6.32e-08!238;UBERON:0003103!6.37e-07!69|ontology_enrichment_uberon_v019=UBERON:0000489;2.66e-19;29!UBERON:0001264;7.56e-19;10!UBERON:0002113;9.95e-19;24!UBERON:0011143;9.95e-19;24!UBERON:0006554;1.30e-18;30!UBERON:0001008;1.30e-18;30!UBERON:0004211;1.73e-18;10!UBERON:0009773;1.73e-18;10!UBERON:0001231;1.73e-18;10!UBERON:0004810;1.73e-18;10!UBERON:0006555;2.60e-17;15!UBERON:0004819;2.60e-17;15!UBERON:0001285;2.60e-17;15!UBERON:0007684;2.60e-17;15!UBERON:0002075;1.38e-14;18!UBERON:0001225;6.05e-10;12!UBERON:0008987;6.05e-10;12!UBERON:0004913;3.31e-09;1!UBERON:0003703;3.31e-09;1!UBERON:0001174;3.31e-09;1!UBERON:0004914;3.31e-09;1!UBERON:0004645;1.42e-08;1!UBERON:0001256;1.42e-08;1!UBERON:0001259;1.42e-08;1!UBERON:0001851;5.54e-08;15!UBERON:0000353;5.54e-08;15!UBERON:0005172;5.88e-07;52!UBERON:0005173;5.88e-07;52|ontology_enrichment_uberon_v019_2=UBERON:0001264,6.90e-19,10;UBERON:0004810,1.50e-18,10;UBERON:0000489,5.60e-18,31;UBERON:0004211,2.25e-17,15;UBERON:0009773,2.25e-17,15;UBERON:0001231,2.25e-17,15;UBERON:0001285,2.25e-17,15;UBERON:0007684,2.25e-17,15;UBERON:0004208,2.25e-17,15;UBERON:0002113,3.39e-17,26;UBERON:0003918,3.39e-17,26;UBERON:0011143,3.39e-17,26;UBERON:0005095,3.39e-17,26;UBERON:0007687,3.39e-17,26;UBERON:0006555,2.93e-16,16;UBERON:0004819,2.93e-16,16;UBERON:0005177,6.58e-16,101;UBERON:0002075,1.24e-14,18;UBERON:0006554,4.04e-14,47;UBERON:0001008,8.59e-14,48;UBERON:0001225,5.64e-10,12;UBERON:0008987,5.64e-10,12;UBERON:0003886,7.33e-10,54;UBERON:0004913,3.31e-09,1;UBERON:0003703,3.31e-09,1;UBERON:0001174,3.31e-09,1;UBERON:0004914,3.31e-09,1;UBERON:0002100,8.43e-09,199;UBERON:0004645,1.22e-08,1;UBERON:0001256,1.22e-08,1;UBERON:0001259,1.22e-08,1;UBERON:0002553,1.43e-08,61;UBERON:0001851,5.24e-08,15;UBERON:0000353,5.24e-08,15;UBERON:0005172,1.02e-07,54;UBERON:0005173,1.02e-07,54;UBERON:0003103,1.85e-07,68;UBERON:0002323,3.10e-07,46;UBERON:0002417,7.74e-07,60;UBERON:0000916,7.74e-07,60;UBERON:0004458,9.67e-07,49|phase1_expression=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.204000691244253,0.313454721478088,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.163461903113459,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.132529768321485,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.134831308160164,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.117408694235822,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.088048434013226,0,0,0,0,0,0,0,0,0,0,0,0,0,0.129271715757778,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.154209693802656,0,0,0,0,0,0,0,0,0,0,1.35359883872224,0.770153371044148,4.70609861506113,2.92278449306521,0.211103257785751,0,0,0.647747748306418,1.54227252690289,0,2.00675909541941,0.509752546090077,0,1.79099803777743,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.107420244868274,0,0.0852266274161009,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.316379424718726,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.213648142254946,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1.98895302764489,0,0,0,0,0,0,0.329607748453519,0,0,0,0,0,0,0,0.539210106883961,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.113942055847001,0,0,0,0,0,0,0,0,0,0,0,0,0,0,4.21996129056054,1.46909527343233,0,0,0,0,0,0,0,0,0,0,0,0,0,3.15614493394321,0,0,0,0,0,0,3.32326936353593,4.96487933813248,1.56966459203613,3.58417289318877,0.569219092059585,2.35746944122336,0,0,0.261177619741208,0,0,0,0,0,0,0,0,1.09633539717401,0,0,0,0.64127056201227,0.213452994739353,0,0,0,0,0.432164393964449,0.372757606696298,0,0.407712618220842,0.418411385249333,0,0.288950589901519,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.739202355635845,3.5857467866569,0,0,0,1.017074150619,0,0,0,0,0,1.02232813071253,0,0,0,0,0,0.855434189421647,0,0,0,0,0,0,0,0,0,0,0.306345576763462,0,0,0,0,0,0,0,0,0,0,0,0,0.941063278792687,0,0,0,0,0,0,0,0,0.228840068396924,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.385239660814607,0,0,0,0,0.244736704506468,0,0,0,0.530067437837643,0,0,0,0.345430341731199,0,0,0,0,0,0,0.737318726261158,2.74705760366215,0,0,0,1.13503190713367,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.196295437002051,0,0,0.346576998451015,0,0.690359926060101,0,0,0.20170506870352,0,0,0,5.47067519003067,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.354581522651905,2.11339663594931,0,0,0.280272163313789,0,10.5804519697124,0,0,0,1.16241425368125,0,0,0,0,0,0,0,0,0,1.60374807980835,0.93061915699296,0.955538938977433,0.671132590786754,0.196300467230486,0.243835849964539,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.561689566824178,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1.54666210360852,0.320182037633146,0,0.269475606319761,0,0,0,0,0,0|short_description=p@chr22:30653345..30653353,-}} | ||
|DPIdataset=robustDPI | |||
|EntrezGene=NA | |||
|GencodeV16b_All_Build2_RSEM10_CPAT_consensus=no_gencodeV16_or_build2_transcript | |||
|HGNC=NA | |||
|TSSclassifier=N | |||
|UniProt=NA | |||
|association_with_transcript=NA | |||
|coexpression_cluster_id=C1262 | |||
|description=CAGE_peak_at_chr22:30653345..30653353,- | |||
|id=chr22:30653345..30653353,- | |||
|ontology_enrichment_celltype=CL:1000497!2.22e-16!18;CL:0002518!2.22e-16!18;CL:1000449!2.88e-15!16;CL:1000507!1.67e-13!12;CL:1000494!1.67e-13!12;CL:0000066!3.52e-13!254;CL:0002149!1.85e-11!6;CL:0002255!1.85e-11!6;CL:0002681!1.84e-09!13;CL:0002584!1.84e-09!13 | |||
|ontology_enrichment_celltype_v019=CL:1000497;9.88e-21;17!CL:0002518;9.88e-21;17!CL:1000507;1.73e-18;10!CL:1000494;1.73e-18;10!CL:1000449;2.60e-17;15!CL:0002681;6.05e-10;12!CL:0002584;6.05e-10;12!CL:1001319;1.42e-08;1!CL:1000600;1.42e-08;1 | |||
|ontology_enrichment_celltype_v019_2=CL:1000497,8.52e-21,17;CL:0002518,8.52e-21,17;CL:1000507,1.50e-18,10;CL:1000494,1.50e-18,10;CL:1000449,2.25e-17,15;CL:0002681,5.64e-10,12;CL:0002584,5.64e-10,12;CL:1001319,1.22e-08,1;CL:1000600,1.22e-08,1 | |||
|ontology_enrichment_development_v019= | |||
|ontology_enrichment_disease=DOID:0050687!4.27e-20!143;DOID:305!1.82e-19!106;DOID:299!3.47e-15!25;DOID:162!6.69e-15!235;DOID:14566!2.48e-14!239;DOID:3001!1.85e-11!6;DOID:0050686!6.29e-07!137;DOID:4468!8.10e-07!2 | |||
|ontology_enrichment_disease_v019=DOID:4468;5.40e-16;2!DOID:1115;5.77e-09;20!DOID:3111;7.17e-09;1!DOID:3603;7.17e-09;1!DOID:299;2.39e-07;25!DOID:3908;7.15e-07;5 | |||
|ontology_enrichment_disease_v019_2=DOID:4468,5.83e-16,2;DOID:0050687,3.01e-10,143;DOID:3111,6.65e-09,1;DOID:3603,6.65e-09,1;DOID:1115,7.35e-09,20;DOID:299,2.26e-07,25;DOID:3908,5.73e-07,5 | |||
|ontology_enrichment_uberon=UBERON:0000058!3.26e-17!26;UBERON:0004211!2.88e-15!16;UBERON:0001285!2.88e-15!16;UBERON:0007684!2.88e-15!16;UBERON:0003220!2.88e-15!16;UBERON:0004208!2.88e-15!16;UBERON:0006555!3.11e-14!17;UBERON:0005103!3.11e-14!17;UBERON:0000083!3.11e-14!17;UBERON:0009201!3.11e-14!17;UBERON:0004819!3.11e-14!17;UBERON:0006553!3.11e-14!17;UBERON:0003074!3.11e-14!17;UBERON:0003060!3.11e-14!17;UBERON:0002113!4.16e-14!27;UBERON:0003918!4.16e-14!27;UBERON:0005095!4.16e-14!27;UBERON:0007687!4.16e-14!27;UBERON:0003886!1.35e-13!63;UBERON:0009773!1.67e-13!12;UBERON:0001231!1.67e-13!12;UBERON:0004810!1.67e-13!12;UBERON:0000489!2.04e-13!32;UBERON:0005177!2.23e-13!107;UBERON:0000080!2.57e-13!18;UBERON:0002120!2.57e-13!18;UBERON:0004875!2.57e-13!18;UBERON:0005721!2.57e-13!18;UBERON:0005754!2.57e-13!18;UBERON:0007297!2.57e-13!18;UBERON:0006554!7.48e-12!44;UBERON:0004876!9.28e-12!20;UBERON:0002553!1.12e-11!70;UBERON:0001008!1.69e-11!45;UBERON:0003887!4.30e-11!21;UBERON:0003064!4.62e-11!37;UBERON:0002075!8.49e-11!18;UBERON:0000464!9.11e-11!104;UBERON:0000466!2.51e-10!126;UBERON:0002114!6.45e-10!12;UBERON:0001264!9.75e-10!10;UBERON:0003922!9.75e-10!10;UBERON:0003923!9.75e-10!10;UBERON:0003924!9.75e-10!10;UBERON:0003921!9.75e-10!10;UBERON:0005172!1.22e-09!55;UBERON:0005173!1.22e-09!55;UBERON:0001851!1.30e-09!16;UBERON:0001225!1.84e-09!13;UBERON:0008987!1.84e-09!13;UBERON:0002294!5.31e-09!7;UBERON:0001173!5.31e-09!7;UBERON:0004912!5.31e-09!7;UBERON:0000353!8.23e-09!17;UBERON:0001045!8.98e-09!11;UBERON:0002108!1.98e-08!14;UBERON:0002417!2.74e-08!61;UBERON:0000916!2.74e-08!61;UBERON:0003104!6.32e-08!238;UBERON:0009142!6.32e-08!238;UBERON:0003103!6.37e-07!69 | |||
|ontology_enrichment_uberon_v019=UBERON:0000489;2.66e-19;29!UBERON:0001264;7.56e-19;10!UBERON:0002113;9.95e-19;24!UBERON:0011143;9.95e-19;24!UBERON:0006554;1.30e-18;30!UBERON:0001008;1.30e-18;30!UBERON:0004211;1.73e-18;10!UBERON:0009773;1.73e-18;10!UBERON:0001231;1.73e-18;10!UBERON:0004810;1.73e-18;10!UBERON:0006555;2.60e-17;15!UBERON:0004819;2.60e-17;15!UBERON:0001285;2.60e-17;15!UBERON:0007684;2.60e-17;15!UBERON:0002075;1.38e-14;18!UBERON:0001225;6.05e-10;12!UBERON:0008987;6.05e-10;12!UBERON:0004913;3.31e-09;1!UBERON:0003703;3.31e-09;1!UBERON:0001174;3.31e-09;1!UBERON:0004914;3.31e-09;1!UBERON:0004645;1.42e-08;1!UBERON:0001256;1.42e-08;1!UBERON:0001259;1.42e-08;1!UBERON:0001851;5.54e-08;15!UBERON:0000353;5.54e-08;15!UBERON:0005172;5.88e-07;52!UBERON:0005173;5.88e-07;52 | |||
|ontology_enrichment_uberon_v019_2=UBERON:0001264,6.90e-19,10;UBERON:0004810,1.50e-18,10;UBERON:0000489,5.60e-18,31;UBERON:0004211,2.25e-17,15;UBERON:0009773,2.25e-17,15;UBERON:0001231,2.25e-17,15;UBERON:0001285,2.25e-17,15;UBERON:0007684,2.25e-17,15;UBERON:0004208,2.25e-17,15;UBERON:0002113,3.39e-17,26;UBERON:0003918,3.39e-17,26;UBERON:0011143,3.39e-17,26;UBERON:0005095,3.39e-17,26;UBERON:0007687,3.39e-17,26;UBERON:0006555,2.93e-16,16;UBERON:0004819,2.93e-16,16;UBERON:0005177,6.58e-16,101;UBERON:0002075,1.24e-14,18;UBERON:0006554,4.04e-14,47;UBERON:0001008,8.59e-14,48;UBERON:0001225,5.64e-10,12;UBERON:0008987,5.64e-10,12;UBERON:0003886,7.33e-10,54;UBERON:0004913,3.31e-09,1;UBERON:0003703,3.31e-09,1;UBERON:0001174,3.31e-09,1;UBERON:0004914,3.31e-09,1;UBERON:0002100,8.43e-09,199;UBERON:0004645,1.22e-08,1;UBERON:0001256,1.22e-08,1;UBERON:0001259,1.22e-08,1;UBERON:0002553,1.43e-08,61;UBERON:0001851,5.24e-08,15;UBERON:0000353,5.24e-08,15;UBERON:0005172,1.02e-07,54;UBERON:0005173,1.02e-07,54;UBERON:0003103,1.85e-07,68;UBERON:0002323,3.10e-07,46;UBERON:0002417,7.74e-07,60;UBERON:0000916,7.74e-07,60;UBERON:0004458,9.67e-07,49 | |||
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|short_description=p@chr22:30653345..30653353,- | |||
}} |
Revision as of 11:26, 12 September 2013
Short description: | p@chr22:30653345..30653353, - |
---|---|
Species: | Human (Homo sapiens) |
DPI dataset: | NA |
TSS-like-by-RIKEN-classifier(Yes/No): | NA |
DHS support(Yes/No): | NA |
Description: | CAGE_peak_at_chr22:30653345..30653353, - |
Coexpression cluster: | C1262_renal_clear_Renal_papillotubular_embryonic_mucinous_serous |
Association with transcript: | NA |
EntrezGene: | NA |
HGNC: | NA |
UniProt: | NA |
Genome view: | ZENBU |
View on UCSC genome browser
CAGE Expression
- Click each plot point to find sample in table
Ontology-based sample term enrichment analysis<b>Summary:</b>This analysis has been performed by utilizing wilcoxon rank sum test.When the number of associated cells/tissues are > n , randomly sampled n cells/tissues are used for P value calculation with rank sum test. this process are repeated several times, and the P values are averaged on the log space <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source dataset<br>data
Ontology term | p-value | n |
---|---|---|
kidney cell | 8.52e-21 | 17 |
kidney epithelial cell | 8.52e-21 | 17 |
kidney tubule cell | 1.50e-18 | 10 |
nephron tubule epithelial cell | 1.50e-18 | 10 |
epithelial cell of nephron | 2.25e-17 | 15 |
kidney cortical cell | 5.64e-10 | 12 |
renal cortical epithelial cell | 5.64e-10 | 12 |
bladder cell | 1.22e-08 | 1 |
lower urinary tract cell | 1.22e-08 | 1 |
Ontology term | p-value | n |
---|---|---|
clear cell adenocarcinoma | 5.83e-16 | 2 |
cell type cancer | 3.01e-10 | 143 |
cystadenocarcinoma | 6.65e-09 | 1 |
mucinous cystadenocarcinoma | 6.65e-09 | 1 |
sarcoma | 7.35e-09 | 20 |
adenocarcinoma | 2.26e-07 | 25 |
non-small cell lung carcinoma | 5.73e-07 | 5 |
Property "DHS support" (as page type) with input value "{{{DHSsupport}}}" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.