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|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0002193!7.50e-29!112;UBERON:0002390!5.39e-27!102;UBERON:0003061!5.39e-27!102;UBERON:0002371!5.13e-24!80;UBERON:0002405!9.83e-22!115;UBERON:0007023!2.00e-20!115;UBERON:0001474!9.25e-20!86;UBERON:0004765!1.83e-14!101;UBERON:0001434!1.83e-14!101;UBERON:0003081!2.25e-08!216;UBERON:0001049!1.05e-07!57;UBERON:0005068!1.05e-07!57;UBERON:0006241!1.05e-07!57;UBERON:0007135!1.05e-07!57;UBERON:0005743!9.96e-07!86
|ontology_enrichment_uberon=UBERON:0002193!7.50e-29!112;UBERON:0002390!5.39e-27!102;UBERON:0003061!5.39e-27!102;UBERON:0002371!5.13e-24!80;UBERON:0002405!9.83e-22!115;UBERON:0007023!2.00e-20!115;UBERON:0001474!9.25e-20!86;UBERON:0004765!1.83e-14!101;UBERON:0001434!1.83e-14!101;UBERON:0003081!2.25e-08!216;UBERON:0001049!1.05e-07!57;UBERON:0005068!1.05e-07!57;UBERON:0006241!1.05e-07!57;UBERON:0007135!1.05e-07!57;UBERON:0005743!9.96e-07!86
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}}
}}

Revision as of 20:23, 8 August 2012


Full id: C4860_Mast_Macrophage_Monocytederived_CD14_Melanocyte_testicular_Dendritic



Phase1 CAGE Peaks

Hg19::chrX:153210060..153210071,-p3@RENBP
Hg19::chrX:153210073..153210106,-p1@RENBP
Hg19::chrX:153210107..153210140,-p2@RENBP


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
myeloid leukocyte2.96e-3176
myeloid cell2.62e-29112
common myeloid progenitor2.62e-29112
granulocyte monocyte progenitor cell4.02e-2871
myeloid lineage restricted progenitor cell4.51e-2870
monopoietic cell7.62e-2563
monocyte7.62e-2563
monoblast7.62e-2563
promonocyte7.62e-2563
hematopoietic stem cell1.17e-24172
angioblastic mesenchymal cell1.17e-24172
macrophage dendritic cell progenitor2.25e-2465
CD14-positive, CD16-negative classical monocyte1.27e-2342
hematopoietic oligopotent progenitor cell1.38e-23165
hematopoietic multipotent progenitor cell1.38e-23165
leukocyte2.29e-23140
hematopoietic cell2.79e-23182
classical monocyte5.54e-2045
hematopoietic lineage restricted progenitor cell2.55e-19124
nongranular leukocyte1.11e-17119
melanocyte2.04e-0710
melanoblast2.04e-0710
pigment cell2.66e-0714
Uber Anatomy
Ontology termp-valuen
hemolymphoid system7.50e-29112
hematopoietic system5.39e-27102
blood island5.39e-27102
bone marrow5.13e-2480
immune system9.83e-22115
adult organism2.00e-20115
bone element9.25e-2086
skeletal element1.83e-14101
skeletal system1.83e-14101
lateral plate mesoderm2.25e-08216
neural tube1.05e-0757
neural rod1.05e-0757
future spinal cord1.05e-0757
neural keel1.05e-0757


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.