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Coexpression cluster:C4759

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Full id: C4759_Placental_Amniotic_Mesenchymal_bone_Myoblast_Sebocyte_glioma



Phase1 CAGE Peaks

Hg19::chr8:49831523..49831551,-p@chr8:49831523..49831551
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Hg19::chr8:49833948..49833973,-p2@SNAI2
Hg19::chr8:49833978..49833996,-p1@SNAI2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
organism subdivision6.73e-18365
surface structure1.65e-1795
multilaminar epithelium6.83e-1682
somite1.21e-1483
paraxial mesoderm1.21e-1483
presomitic mesoderm1.21e-1483
presumptive segmental plate1.21e-1483
trunk paraxial mesoderm1.21e-1483
presumptive paraxial mesoderm1.21e-1483
multi-cellular organism1.75e-12659
trunk8.71e-12216
dermomyotome1.47e-1170
multi-tissue structure1.67e-11347
integument2.30e-1145
integumental system2.30e-1145
trunk mesenchyme5.01e-11143
skin of body5.96e-1040
mesenchyme9.51e-10238
entire embryonic mesenchyme9.51e-10238
skeletal muscle tissue2.01e-0961
striated muscle tissue2.01e-0961
myotome2.01e-0961
muscle tissue3.29e-0963
musculature3.29e-0963
musculature of body3.29e-0963
anatomical system4.58e-09625
organ component layer5.43e-0957
anatomical group7.90e-09626
embryonic structure3.50e-07605
developing anatomical structure3.50e-07605
embryo3.99e-07612
germ layer6.27e-07604
embryonic tissue6.27e-07604
presumptive structure6.27e-07604
epiblast (generic)6.27e-07604
cell layer6.63e-07312
endoderm-derived structure8.82e-07169
endoderm8.82e-07169
presumptive endoderm8.82e-07169


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.