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Coexpression cluster:C4862

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Full id: C4862_Neutrophils_large_meningioma_Pericytes_leiomyoma_Nucleus_Dendritic



Phase1 CAGE Peaks

Hg19::chrX:153761003..153761024,-p4@G6PD
Hg19::chrX:153763451..153763480,-p1@M12996
Hg19::chrX:153764189..153764228,-p@chrX:153764189..153764228
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0006010glucose 6-phosphate utilization0.00123631225715295
GO:0051156glucose 6-phosphate metabolic process0.00123631225715295
GO:0004345glucose-6-phosphate dehydrogenase activity0.0024726245143059
GO:0006740NADPH regeneration0.00321441186859767
GO:0006098pentose-phosphate shunt0.00321441186859767
GO:0006739NADP metabolic process0.00350288472860002
GO:0006769nicotinamide metabolic process0.00582832921229247
GO:0019362pyridine nucleotide metabolic process0.00587248322147651
GO:0006733oxidoreduction coenzyme metabolic process0.0068684014286275
GO:0006767water-soluble vitamin metabolic process0.00791239844577887
GO:0006766vitamin metabolic process0.00966571401046851
GO:0006007glucose catabolic process0.0118685976686683
GO:0019320hexose catabolic process0.0118685976686683
GO:0016616oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor0.0118685976686683
GO:0046365monosaccharide catabolic process0.0118685976686683
GO:0046164alcohol catabolic process0.0118685976686683
GO:0016614oxidoreductase activity, acting on CH-OH group of donors0.0118685976686683
GO:0044275cellular carbohydrate catabolic process0.0118685976686683
GO:0016052carbohydrate catabolic process0.0118685976686683
GO:0006006glucose metabolic process0.0118685976686683
GO:0019318hexose metabolic process0.0153977072027231
GO:0005996monosaccharide metabolic process0.0153977072027231
GO:0006732coenzyme metabolic process0.0154807795678282
GO:0009117nucleotide metabolic process0.0169622041681385
GO:0051186cofactor metabolic process0.0169622041681385
GO:0055086nucleobase, nucleoside and nucleotide metabolic process0.0174510230144282
GO:0006066alcohol metabolic process0.0203762575715949
GO:0044262cellular carbohydrate metabolic process0.0219003885552808
GO:0044265cellular macromolecule catabolic process0.0222962520858963
GO:0009057macromolecule catabolic process0.0257565053573531
GO:0005975carbohydrate metabolic process0.031255519251148
GO:0044248cellular catabolic process0.031255519251148
GO:0009056catabolic process0.0364524795821157



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
animal cell9.71e-33679
eukaryotic cell9.71e-33679
native cell1.37e-25722
somatic cell2.33e-23591
mesodermal cell6.10e-14119
non-terminally differentiated cell7.93e-14180
embryonic cell4.44e-13248
somatic stem cell7.93e-12436
multi fate stem cell1.20e-11430
stem cell1.50e-10444
contractile cell4.63e-1059
fibroblast1.09e-0975
epithelial cell1.54e-08254
muscle cell2.10e-0854
muscle precursor cell2.53e-0857
myoblast2.53e-0857
multi-potent skeletal muscle stem cell2.53e-0857
electrically responsive cell8.34e-0860
electrically active cell8.34e-0860
lining cell2.53e-0757
barrier cell2.53e-0757
connective tissue cell5.46e-07365
smooth muscle cell7.32e-0742
smooth muscle myoblast7.32e-0742


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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