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Coexpression cluster:C4158

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Full id: C4158_Smooth_Mesenchymal_Cardiac_Nucleus_extraskeletal_mucinous_Lymphatic



Phase1 CAGE Peaks

Hg19::chr2:188330292..188330295,-p5@TFPI
Hg19::chr2:188330646..188330688,-p4@TFPI
Hg19::chr2:188330885..188330910,-p6@TFPI


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
unilaminar epithelium3.64e-21148
mesenchyme5.92e-19160
entire embryonic mesenchyme5.92e-19160
trunk mesenchyme3.37e-17122
trunk1.08e-15199
epithelial tube2.15e-15117
organism subdivision2.25e-14264
vasculature2.92e-1278
vascular system2.92e-1278
muscle tissue4.73e-1264
musculature4.73e-1264
musculature of body4.73e-1264
skeletal muscle tissue1.25e-1162
striated muscle tissue1.25e-1162
myotome1.25e-1162
somite1.88e-1171
presomitic mesoderm1.88e-1171
presumptive segmental plate1.88e-1171
dermomyotome1.88e-1171
trunk paraxial mesoderm1.88e-1171
splanchnic layer of lateral plate mesoderm4.19e-1183
paraxial mesoderm6.28e-1172
presumptive paraxial mesoderm6.28e-1172
dense mesenchyme tissue9.07e-1173
epithelial vesicle3.69e-1078
multilaminar epithelium4.36e-1083
multi-tissue structure5.10e-10342
vessel5.89e-1068
anatomical cluster6.44e-10373
multi-cellular organism2.39e-09656
cardiovascular system2.95e-09109
epithelial tube open at both ends5.62e-0959
blood vessel5.62e-0959
blood vasculature5.62e-0959
vascular cord5.62e-0959
circulatory system7.54e-09112
cell layer9.24e-08309
epithelium1.24e-07306
anatomical system1.55e-07624
gut epithelium1.60e-0754
anatomical group2.33e-07625
artery3.13e-0742
arterial blood vessel3.13e-0742
arterial system3.13e-0742
digestive system4.74e-07145
digestive tract4.74e-07145
primitive gut4.74e-07145


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.