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MCL coexpression mm9:1351

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Phase1 CAGE Peaks

 Short description
Mm9::chr13:74945332..74945347,-p11@Cast
Mm9::chr16:16213418..16213457,+p1@Pkp2
Mm9::chr9:71402786..71402790,-p@chr9:71402786..71402790
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Mm9::chr9:71440090..71440104,-p3@Gcom1
Mm9::chr9:71440119..71440150,-p2@Gcom1
Mm9::chr9:71440153..71440179,-p1@Gcom1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0030161calpain inhibitor activity0.00339670191201446
GO:0004869cysteine protease inhibitor activity0.0475186538194094



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
endoderm-derived structure9.89e-09118
endoderm9.89e-09118
presumptive endoderm9.89e-09118
digestive system2.72e-08116
digestive tract2.72e-08116
primitive gut2.72e-08116
primary circulatory organ4.15e-0818
heart4.15e-0818
primitive heart tube4.15e-0818
primary heart field4.15e-0818
anterior lateral plate mesoderm4.15e-0818
heart tube4.15e-0818
heart primordium4.15e-0818
cardiac mesoderm4.15e-0818
cardiogenic plate4.15e-0818
heart rudiment4.15e-0818
subdivision of digestive tract1.35e-07114
intestine3.66e-0731
thoracic cavity element4.35e-0717
thoracic segment organ4.35e-0717
thoracic cavity4.35e-0717
thoracic segment of trunk4.35e-0717
respiratory primordium4.35e-0717
endoderm of foregut4.35e-0717
gastrointestinal system5.37e-0747
lung5.97e-0714
respiratory tube5.97e-0714
respiration organ5.97e-0714
pair of lungs5.97e-0714
lung primordium5.97e-0714
lung bud5.97e-0714
epithelial bud8.38e-0717


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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