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Coexpression cluster:C1323

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Full id: C1323_heart_Lymphatic_left_mesenchymal_skeletal_bone_Adipocyte



Phase1 CAGE Peaks

Hg19::chr10:92672040..92672054,-p@chr10:92672040..92672054
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Hg19::chr10:92675596..92675615,-p@chr10:92675596..92675615
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Hg19::chr10:92679951..92679969,-p@chr10:92679951..92679969
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Hg19::chr10:92679988..92680056,-p@chr10:92679988..92680056
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Hg19::chr10:92680062..92680080,-p@chr10:92680062..92680080
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Hg19::chr10:92680836..92680853,-p1@ANKRD1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
vasculature1.02e-2178
vascular system1.02e-2178
circulatory system2.31e-21112
vessel3.69e-2168
epithelial tube2.32e-20117
unilaminar epithelium2.01e-19148
cardiovascular system2.48e-19109
splanchnic layer of lateral plate mesoderm1.21e-1883
epithelial tube open at both ends2.20e-1859
blood vessel2.20e-1859
blood vasculature2.20e-1859
vascular cord2.20e-1859
blood vessel endothelium2.83e-1518
endothelium2.83e-1518
cardiovascular system endothelium2.83e-1518
simple squamous epithelium3.74e-1422
squamous epithelium1.55e-1125
cell layer4.40e-11309
epithelium9.98e-11306
primary circulatory organ1.64e-1027
trunk mesenchyme2.26e-10122
trunk1.54e-09199
mesenchyme1.62e-09160
entire embryonic mesenchyme1.62e-09160
endothelial tube7.30e-099
arterial system endothelium7.30e-099
endothelium of artery7.30e-099
artery2.71e-0842
arterial blood vessel2.71e-0842
arterial system2.71e-0842
heart3.14e-0824
primitive heart tube3.14e-0824
primary heart field3.14e-0824
anterior lateral plate mesoderm3.14e-0824
heart tube3.14e-0824
heart primordium3.14e-0824
cardiac mesoderm3.14e-0824
cardiogenic plate3.14e-0824
heart rudiment3.14e-0824
epithelial vesicle3.54e-0878
skeletal muscle tissue3.89e-0862
striated muscle tissue3.89e-0862
myotome3.89e-0862
somite5.06e-0871
presomitic mesoderm5.06e-0871
presumptive segmental plate5.06e-0871
dermomyotome5.06e-0871
trunk paraxial mesoderm5.06e-0871
organism subdivision8.29e-08264
umbilical blood vessel9.11e-089
paraxial mesoderm9.32e-0872
presumptive paraxial mesoderm9.32e-0872
muscle tissue1.46e-0764
musculature1.46e-0764
musculature of body1.46e-0764
mesoderm1.57e-07315
mesoderm-derived structure1.57e-07315
presumptive mesoderm1.57e-07315
dense mesenchyme tissue1.68e-0773
vein3.87e-079
venous blood vessel3.87e-079
venous system3.87e-079


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.