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|full_id=C4714_Adipocyte_Osteoblast_Preadipocyte_Fibroblast_Mesenchymal_tenocyte_mesenchymal
|full_id=C4714_Adipocyte_Osteoblast_Preadipocyte_Fibroblast_Mesenchymal_tenocyte_mesenchymal
|id=C4714
|id=C4714
|ontology_enrichment_celltype=CL:0000055!1.74e-35!180;CL:0000057!3.63e-20!75;CL:0000183!9.58e-18!59;CL:0000680!1.26e-16!57;CL:0000056!1.26e-16!57;CL:0000355!1.26e-16!57;CL:0000187!1.13e-15!54;CL:0000393!1.61e-13!60;CL:0000211!1.61e-13!60;CL:0000222!3.61e-13!119;CL:0000192!4.86e-13!42;CL:0000514!4.86e-13!42;CL:0002371!1.56e-09!591;CL:0000359!1.90e-09!32;CL:0002334!2.03e-08!12;CL:0000144!1.47e-07!625;CL:0000048!2.41e-07!430;CL:0000548!3.21e-07!679;CL:0000004!3.21e-07!679;CL:0000255!3.21e-07!679;CL:0002620!3.74e-07!23;CL:0000012!9.33e-07!682
|ontology_enrichment_disease=DOID:2394!9.54e-07!14
|ontology_enrichment_uberon=UBERON:0000914!5.95e-18!83;UBERON:0002329!5.95e-18!83;UBERON:0003077!5.95e-18!83;UBERON:0003059!5.95e-18!83;UBERON:0007282!5.95e-18!83;UBERON:0009618!5.95e-18!83;UBERON:0007285!5.95e-18!83;UBERON:0002049!1.41e-17!79;UBERON:0007798!1.41e-17!79;UBERON:0005256!2.55e-17!143;UBERON:0004290!3.53e-17!70;UBERON:0001134!7.51e-16!61;UBERON:0002036!7.51e-16!61;UBERON:0003082!7.51e-16!61;UBERON:0002385!1.52e-15!63;UBERON:0001015!1.52e-15!63;UBERON:0000383!1.52e-15!63;UBERON:0004872!1.49e-14!84;UBERON:0000055!4.00e-14!69;UBERON:0000486!5.44e-14!82;UBERON:0003914!5.62e-14!118;UBERON:0000475!1.35e-13!365;UBERON:0002100!2.12e-13!216;UBERON:0000490!1.14e-12!138;UBERON:0001009!3.97e-12!113;UBERON:0004535!4.65e-12!110;UBERON:0001981!1.73e-11!60;UBERON:0007500!1.73e-11!60;UBERON:0004537!1.73e-11!60;UBERON:0006965!1.73e-11!60;UBERON:0000468!2.74e-11!659;UBERON:0000119!1.40e-10!312;UBERON:0000483!4.54e-10!309;UBERON:0001637!4.03e-09!42;UBERON:0003509!4.03e-09!42;UBERON:0004572!4.03e-09!42;UBERON:0003102!5.84e-09!95;UBERON:0003104!6.49e-09!238;UBERON:0009142!6.49e-09!238;UBERON:0000477!7.26e-09!286;UBERON:0001013!1.33e-08!14;UBERON:0000481!1.71e-08!347;UBERON:0002199!2.67e-08!45;UBERON:0002416!2.67e-08!45;UBERON:0004111!8.35e-08!241;UBERON:0000480!9.73e-08!626;UBERON:0004573!1.19e-07!33;UBERON:0004571!1.19e-07!33;UBERON:0000467!1.35e-07!625
}}
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Revision as of 14:52, 21 May 2012


Full id: C4714_Adipocyte_Osteoblast_Preadipocyte_Fibroblast_Mesenchymal_tenocyte_mesenchymal



Phase1 CAGE Peaks

Hg19::chr8:104383700..104383709,+p4@CTHRC1
Hg19::chr8:104383728..104383756,+p2@CTHRC1
Hg19::chr8:104383759..104383821,+p1@CTHRC1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Uber Anatomy
Ontology termp-valuen
somite5.95e-1883
paraxial mesoderm5.95e-1883
presomitic mesoderm5.95e-1883
presumptive segmental plate5.95e-1883
trunk paraxial mesoderm5.95e-1883
presumptive paraxial mesoderm5.95e-1883
vasculature1.41e-1779
vascular system1.41e-1779
trunk mesenchyme2.55e-17143
dermomyotome3.53e-1770
skeletal muscle tissue7.51e-1661
striated muscle tissue7.51e-1661
myotome7.51e-1661
muscle tissue1.52e-1563
musculature1.52e-1563
musculature of body1.52e-1563
splanchnic layer of lateral plate mesoderm1.49e-1484
vessel4.00e-1469
multilaminar epithelium5.44e-1482
epithelial tube5.62e-14118
organism subdivision1.35e-13365
trunk2.12e-13216
unilaminar epithelium1.14e-12138
circulatory system3.97e-12113
cardiovascular system4.65e-12110
blood vessel1.73e-1160
epithelial tube open at both ends1.73e-1160
blood vasculature1.73e-1160
vascular cord1.73e-1160
multi-cellular organism2.74e-11659
cell layer1.40e-10312
epithelium4.54e-10309
artery4.03e-0942
arterial blood vessel4.03e-0942
arterial system4.03e-0942
surface structure5.84e-0995
mesenchyme6.49e-09238
entire embryonic mesenchyme6.49e-09238
anatomical cluster7.26e-09286
adipose tissue1.33e-0814
multi-tissue structure1.71e-08347
integument2.67e-0845
integumental system2.67e-0845
anatomical conduit8.35e-08241
anatomical group9.73e-08626
systemic artery1.19e-0733
systemic arterial system1.19e-0733
anatomical system1.35e-07625
Disease
Ontology termp-valuen
ovarian cancer9.54e-0714


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.