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Coexpression cluster:C501

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Full id: C501_CD14_trachea_throat_Basophils_acute_Peripheral_Macrophage



Phase1 CAGE Peaks

Hg19::chr12:69742152..69742171,+p1@LYZ
Hg19::chr12:69743902..69743926,+p@chr12:69743902..69743926
+
Hg19::chr12:69743928..69743957,+p@chr12:69743928..69743957
+
Hg19::chr12:69743960..69744015,+p@chr12:69743960..69744015
+
Hg19::chr12:69745988..69746056,+p@chr12:69745988..69746056
+
Hg19::chr12:69746926..69746936,+p8@LYZ
Hg19::chr12:69746937..69747004,+p4@LYZ
Hg19::chr12:69747008..69747026,+p7@LYZ
Hg19::chr12:69747028..69747035,+p9@LYZ
Hg19::chr12:69747041..69747093,+p5@LYZ
Hg19::chr12:69747096..69747192,+p2@LYZ
Hg19::chr12:69747193..69747262,+p3@LYZ
Hg19::chr12:69747538..69747621,+p6@LYZ
Hg19::chr12:69747643..69747652,+p10@LYZ
Hg19::chr12:69747658..69747691,+p@chr12:69747658..69747691
+
Hg19::chr12:69747692..69747716,+p@chr12:69747692..69747716
+
Hg19::chr12:69747735..69747742,+p@chr12:69747735..69747742
+
Hg19::chr12:69747757..69747771,+p@chr12:69747757..69747771
+
Hg19::chr12:69747775..69747790,+p@chr12:69747775..69747790
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
monopoietic cell3.04e-7959
monocyte3.04e-7959
monoblast3.04e-7959
promonocyte3.04e-7959
macrophage dendritic cell progenitor1.64e-7861
myeloid leukocyte1.83e-7672
defensive cell2.89e-7148
phagocyte2.89e-7148
granulocyte monocyte progenitor cell1.06e-6967
myeloid lineage restricted progenitor cell9.26e-6966
myeloid cell1.27e-62108
common myeloid progenitor1.27e-62108
classical monocyte1.49e-6242
CD14-positive, CD16-negative classical monocyte1.49e-6242
leukocyte5.06e-46136
hematopoietic stem cell5.32e-45168
angioblastic mesenchymal cell5.32e-45168
nongranular leukocyte1.12e-43115
hematopoietic cell2.25e-41177
hematopoietic oligopotent progenitor cell3.77e-41161
hematopoietic multipotent progenitor cell3.77e-41161
hematopoietic lineage restricted progenitor cell1.07e-37120
stuff accumulating cell1.88e-3187
intermediate monocyte9.95e-139
CD14-positive, CD16-positive monocyte9.95e-139
mesenchymal cell1.32e-10354
connective tissue cell5.74e-10361
macrophage8.86e-106
motile cell8.73e-08386
Uber Anatomy
Ontology termp-valuen
hematopoietic system1.94e-7398
blood island1.94e-7398
hemolymphoid system3.28e-68108
bone marrow3.41e-6176
immune system1.58e-5693
bone element3.09e-5582
skeletal element1.56e-4890
skeletal system1.12e-41100
lateral plate mesoderm1.30e-28203
musculoskeletal system6.23e-19167
mesoderm2.63e-12315
mesoderm-derived structure2.63e-12315
presumptive mesoderm2.63e-12315
blood1.75e-1115
haemolymphatic fluid1.75e-1115
organism substance1.75e-1115
connective tissue1.62e-09371


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.12.8722e-05
MA0004.10.193314
MA0006.10.0925234
MA0007.10.532323
MA0009.12.42313
MA0014.14.97928e-05
MA0017.10.114723
MA0019.10.305657
MA0024.10.485346
MA0025.10.70396
MA0027.12.15732
MA0028.10.101383
MA0029.10.50258
MA0030.10.492344
MA0031.10.435419
MA0038.10.269828
MA0040.11.26613
MA0041.11.12415
MA0042.10.541224
MA0043.10.580321
MA0046.11.39813
MA0048.10.00932809
MA0050.10.184533
MA0051.10.266537
MA0052.11.27353
MA0055.10.106762
MA0056.10
MA0057.10.00844127
MA0058.10.12994
MA0059.10.129144
MA0060.10.0387582
MA0061.10.029485
MA0063.10
MA0066.10.270161
MA0067.10.879057
MA0068.10.0187693
MA0069.10.566544
MA0070.10.556335
MA0071.11.25272
MA0072.10.552241
MA0073.11.8214e-07
MA0074.10.265952
MA0076.10.139892
MA0077.10.545231
MA0078.10.346453
MA0081.10.129245
MA0083.10.586921
MA0084.11.06048
MA0087.10.550016
MA0088.10.00268743
MA0089.10
MA0090.10.149167
MA0091.10.195166
MA0092.10.168981
MA0093.10.0941737
MA0095.10
MA0098.10
MA0100.10.280715
MA0101.10.0959778
MA0103.10.0875643
MA0105.10.00666152
MA0106.10.302526
MA0107.10.0591705
MA0108.20.432749
MA0109.10
MA0111.11.48573
MA0113.11.53038
MA0114.10.0569149
MA0115.10.805883
MA0116.10.0607301
MA0117.10.614633
MA0119.10.119385
MA0122.10.638621
MA0124.11.8075
MA0125.10.687166
MA0130.10
MA0131.10.361613
MA0132.10
MA0133.10
MA0135.10.60795
MA0136.10.27535
MA0139.10.0257123
MA0140.10.669735
MA0141.14.04725
MA0142.11.85154
MA0143.11.53089
MA0144.10.0508083
MA0145.10.00353814
MA0146.10.0735098
MA0147.10.0623218
MA0148.10.211171
MA0149.10.230803
MA0062.20.027823
MA0035.20.668495
MA0039.25.11969e-05
MA0138.20.347473
MA0002.20.138689
MA0137.20.105044
MA0104.20.0384802
MA0047.20.292798
MA0112.20.421916
MA0065.20.468021
MA0150.10.145358
MA0151.10
MA0152.10.243034
MA0153.10.67139
MA0154.10.00634321
MA0155.10.00260895
MA0156.10.106343
MA0157.10.384449
MA0158.10
MA0159.10.487475
MA0160.13.42737
MA0161.10
MA0162.10.00017322
MA0163.10.0262946
MA0164.10.32594
MA0080.20.0942207
MA0018.20.30364
MA0099.20.243305
MA0079.21.92865e-16
MA0102.21.09681
MA0258.11.08978
MA0259.10.0662172
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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