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MCL coexpression mm9:974

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Phase1 CAGE Peaks

 Short description
Mm9::chr18:35899649..35899675,-p@chr18:35899649..35899675
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Mm9::chr1:108608936..108608961,-p@chr1:108608936..108608961
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Mm9::chr1:108608965..108609005,-p@chr1:108608965..108609005
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Mm9::chr1:108609006..108609033,-p@chr1:108609006..108609033
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Mm9::chr1:108610539..108610626,-p2@Bcl2
Mm9::chr1:108610794..108610907,-p1@Bcl2
Mm9::chr1:36824259..36824270,+p@chr1:36824259..36824270
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Mm9::chrX:7455424..7455440,+p1@Pim2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0008637apoptotic mitochondrial changes0.000390873835132874
GO:0008632apoptotic program0.00134258362392082
GO:0007005mitochondrion organization and biogenesis0.00168168780260459
GO:0006916anti-apoptosis0.00171237262068775
GO:0045069regulation of viral genome replication0.00368027499270053
GO:0043066negative regulation of apoptosis0.00368027499270053
GO:0043069negative regulation of programmed cell death0.00368027499270053
GO:0050792regulation of viral reproduction0.00417442749767467
GO:0019079viral genome replication0.00417442749767467
GO:0046902regulation of mitochondrial membrane permeability0.00417442749767467
GO:0019058viral infectious cycle0.00521774847851113
GO:0051881regulation of mitochondrial membrane potential0.00521774847851113
GO:0022415viral reproductive process0.00802642572719521
GO:0016032viral reproduction0.00894324147501408
GO:0042981regulation of apoptosis0.0099930817688357
GO:0043067regulation of programmed cell death0.0099930817688357
GO:0001836release of cytochrome c from mitochondria0.013498842062112
GO:0007006mitochondrial membrane organization and biogenesis0.0150652381159983
GO:0031069hair follicle morphogenesis0.0153693601552006
GO:0006915apoptosis0.0191118344438876
GO:0012501programmed cell death0.0191118344438876
GO:0008219cell death0.0191118344438876
GO:0016265death0.0191118344438876
GO:0006839mitochondrial transport0.0191118344438876
GO:0043524negative regulation of neuron apoptosis0.0191802807039359
GO:0043523regulation of neuron apoptosis0.0255853503827637
GO:0048523negative regulation of cellular process0.0255853503827637
GO:0051402neuron apoptosis0.0255853503827637
GO:0022404molting cycle process0.0255853503827637
GO:0001942hair follicle development0.0255853503827637
GO:0022405hair cycle process0.0255853503827637
GO:0048519negative regulation of biological process0.0255853503827637
GO:0042391regulation of membrane potential0.0255853503827637
GO:0042633hair cycle0.0255853503827637
GO:0042303molting cycle0.0255853503827637
GO:0048730epidermis morphogenesis0.0283362027210767
GO:0007242intracellular signaling cascade0.0288821106596986
GO:0046982protein heterodimerization activity0.032851388256512
GO:0006996organelle organization and biogenesis0.0335915438424823
GO:0048468cell development0.0335915438424823
GO:0048729tissue morphogenesis0.0380282311161415
GO:0008544epidermis development0.0474624550720922
GO:0007398ectoderm development0.0487598082243745



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.848341
MA0004.10.434673
MA0006.10.271714
MA0007.10.419994
MA0009.10.870101
MA0014.10.325341
MA0017.10.296816
MA0019.10.688051
MA0024.10.826339
MA0025.11.10341
MA0027.12.51754
MA0028.10.769859
MA0029.10.804619
MA0030.10.811181
MA0031.10.775627
MA0038.10.577528
MA0040.10.882616
MA0041.10.360875
MA0042.10.348174
MA0043.10.966833
MA0046.10.906029
MA0048.10.102483
MA0050.10.472794
MA0051.10.586414
MA0052.10.890676
MA0055.10.523649
MA0056.10
MA0057.10.31126
MA0058.10.341628
MA0059.10.353484
MA0060.10.197678
MA0061.10.224905
MA0063.10
MA0066.10.566617
MA0067.11.21448
MA0068.10.319589
MA0069.10.891016
MA0070.10.881319
MA0071.10.471969
MA0072.10.872842
MA0073.10.312272
MA0074.10.531046
MA0076.10.315013
MA0077.10.851175
MA0078.10.61926
MA0081.10.375851
MA0083.10.96604
MA0084.11.54225
MA0087.10.922929
MA0088.10.853781
MA0089.10
MA0090.11.03628
MA0091.10.447561
MA0092.10.401504
MA0093.10.289361
MA0095.10
MA0098.10
MA0100.10.519598
MA0101.10.362124
MA0103.11.49915
MA0105.10.133231
MA0106.10.626997
MA0107.10.301222
MA0108.20.710846
MA0109.10
MA0111.10.415012
MA0113.10.598933
MA0114.10.222763
MA0115.10.969632
MA0116.10.27152
MA0117.10.937363
MA0119.10.362692
MA0122.10.957212
MA0124.11.16127
MA0125.11.0872
MA0130.10
MA0131.10.683521
MA0132.10
MA0133.10
MA0135.11.00325
MA0136.10.550755
MA0139.12.9589
MA0140.10.519484
MA0141.10.325895
MA0142.10.761136
MA0143.10.615203
MA0144.10.225588
MA0145.10.246409
MA0146.10.636109
MA0147.10.236889
MA0148.10.450593
MA0149.10.367458
MA0062.20.84271
MA0035.20.524137
MA0039.20.027551
MA0138.20.675599
MA0002.21.56981
MA0137.20.32312
MA0104.20.18504
MA0047.20.576767
MA0112.20.2464
MA0065.20.0704227
MA0150.11.07698
MA0151.10
MA0152.10.576873
MA0153.11.01988
MA0154.10.330759
MA0155.10.275377
MA0156.10.314185
MA0157.10.729116
MA0158.10
MA0159.10.246253
MA0160.11.14982
MA0161.10
MA0162.10.230918
MA0163.10.991519
MA0164.10.551114
MA0080.20.302064
MA0018.20.560731
MA0099.20.669311
MA0079.21.00617
MA0102.21.59466
MA0258.11.13923
MA0259.10.227035
MA0442.10
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