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|full_id=C3641_granulocyte_acute_Dendritic_CD133_NK_chronic_biphenotypic
|full_id=C3641_granulocyte_acute_Dendritic_CD133_NK_chronic_biphenotypic
|id=C3641
|id=C3641
|ontology_enrichment_celltype=CL:0000037!4.51e-78!172;CL:0000566!4.51e-78!172;CL:0002032!7.67e-72!165;CL:0000837!7.67e-72!165;CL:0000988!4.37e-70!182;CL:0000738!7.74e-59!140;CL:0002031!8.40e-51!124;CL:0002087!4.54e-50!119;CL:0000763!5.68e-37!112;CL:0000049!5.68e-37!112;CL:0000542!1.27e-31!53;CL:0000051!1.27e-31!53;CL:0000838!4.09e-31!52;CL:0000766!1.92e-21!76;CL:0000557!3.70e-20!71;CL:0000839!5.78e-19!70;CL:0002009!5.13e-18!65;CL:0002194!4.32e-17!63;CL:0000576!4.32e-17!63;CL:0000040!4.32e-17!63;CL:0000559!4.32e-17!63;CL:0000084!4.89e-17!25;CL:0000827!4.89e-17!25;CL:0002057!8.69e-15!42;CL:0000860!1.79e-13!45;CL:0000945!1.97e-13!24;CL:0000826!1.97e-13!24;CL:0000791!1.89e-12!18;CL:0000789!1.89e-12!18;CL:0002420!1.89e-12!18;CL:0002419!1.89e-12!18;CL:0000790!1.89e-12!18;CL:0000134!1.56e-10!358;CL:0002320!8.68e-10!365;CL:0000625!8.83e-09!11;CL:0000219!6.07e-07!390;CL:0000236!9.63e-07!14
|ontology_enrichment_disease=DOID:2531!4.20e-26!51;DOID:0060083!4.20e-26!51;DOID:1240!4.34e-21!39;DOID:8692!2.35e-16!31;DOID:0060058!2.89e-08!10
|ontology_enrichment_uberon=UBERON:0002390!2.41e-27!102;UBERON:0003061!2.41e-27!102;UBERON:0002193!1.02e-24!112;UBERON:0002371!1.21e-17!80;UBERON:0001474!1.40e-15!86;UBERON:0002405!1.35e-13!115;UBERON:0004765!3.40e-11!101;UBERON:0001434!3.40e-11!101;UBERON:0002384!1.03e-08!375;UBERON:0007023!9.62e-08!115
}}
}}

Revision as of 14:39, 21 May 2012


Full id: C3641_granulocyte_acute_Dendritic_CD133_NK_chronic_biphenotypic



Phase1 CAGE Peaks

Hg19::chr17:4337199..4337254,+p1@SPNS3
Hg19::chr19:55767076..55767090,-p5@PPP6R1
Hg19::chr19:55767125..55767147,-p3@PPP6R1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen
hematopoietic stem cell4.51e-78172
angioblastic mesenchymal cell4.51e-78172
hematopoietic oligopotent progenitor cell7.67e-72165
hematopoietic multipotent progenitor cell7.67e-72165
hematopoietic cell4.37e-70182
leukocyte7.74e-59140
hematopoietic lineage restricted progenitor cell8.40e-51124
nongranular leukocyte4.54e-50119
myeloid cell5.68e-37112
common myeloid progenitor5.68e-37112
lymphocyte1.27e-3153
common lymphoid progenitor1.27e-3153
lymphoid lineage restricted progenitor cell4.09e-3152
myeloid leukocyte1.92e-2176
granulocyte monocyte progenitor cell3.70e-2071
myeloid lineage restricted progenitor cell5.78e-1970
macrophage dendritic cell progenitor5.13e-1865
monopoietic cell4.32e-1763
monocyte4.32e-1763
monoblast4.32e-1763
promonocyte4.32e-1763
T cell4.89e-1725
pro-T cell4.89e-1725
CD14-positive, CD16-negative classical monocyte8.69e-1542
classical monocyte1.79e-1345
lymphocyte of B lineage1.97e-1324
pro-B cell1.97e-1324
mature alpha-beta T cell1.89e-1218
alpha-beta T cell1.89e-1218
immature T cell1.89e-1218
mature T cell1.89e-1218
immature alpha-beta T cell1.89e-1218
mesenchymal cell1.56e-10358
connective tissue cell8.68e-10365
CD8-positive, alpha-beta T cell8.83e-0911
motile cell6.07e-07390
B cell9.63e-0714
Uber Anatomy
Ontology termp-valuen
hematopoietic system2.41e-27102
blood island2.41e-27102
hemolymphoid system1.02e-24112
bone marrow1.21e-1780
bone element1.40e-1586
immune system1.35e-13115
skeletal element3.40e-11101
skeletal system3.40e-11101
connective tissue1.03e-08375
adult organism9.62e-08115
Disease
Ontology termp-valuen
hematologic cancer4.20e-2651
immune system cancer4.20e-2651
leukemia4.34e-2139
myeloid leukemia2.35e-1631
lymphoma2.89e-0810


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.