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|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0004177!2.45e-09!29;UBERON:0005057!2.45e-09!29;UBERON:0002193!3.86e-09!48;UBERON:0002405!3.86e-09!48;UBERON:0002390!5.66e-09!45;UBERON:0003061!5.66e-09!45;UBERON:0000077!1.74e-08!35;UBERON:0000072!3.91e-08!27;UBERON:0002370!5.69e-08!23;UBERON:0000974!5.69e-08!23;UBERON:0004807!5.69e-08!23;UBERON:0005058!5.69e-08!23;UBERON:0003351!5.69e-08!23;UBERON:0009113!5.69e-08!23;UBERON:0003295!5.69e-08!23;UBERON:0009722!5.69e-08!23;UBERON:0005562!5.69e-08!23;UBERON:0007690!5.69e-08!23;UBERON:0006562!1.87e-07!24;UBERON:0001557!1.87e-07!24;UBERON:0001042!1.87e-07!24;UBERON:0008814!1.87e-07!24;UBERON:0009145!1.87e-07!24;UBERON:0002384!4.63e-07!46;UBERON:0003408!7.52e-07!24
|ontology_enrichment_uberon=UBERON:0004177!2.45e-09!29;UBERON:0005057!2.45e-09!29;UBERON:0002193!3.86e-09!48;UBERON:0002405!3.86e-09!48;UBERON:0002390!5.66e-09!45;UBERON:0003061!5.66e-09!45;UBERON:0000077!1.74e-08!35;UBERON:0000072!3.91e-08!27;UBERON:0002370!5.69e-08!23;UBERON:0000974!5.69e-08!23;UBERON:0004807!5.69e-08!23;UBERON:0005058!5.69e-08!23;UBERON:0003351!5.69e-08!23;UBERON:0009113!5.69e-08!23;UBERON:0003295!5.69e-08!23;UBERON:0009722!5.69e-08!23;UBERON:0005562!5.69e-08!23;UBERON:0007690!5.69e-08!23;UBERON:0006562!1.87e-07!24;UBERON:0001557!1.87e-07!24;UBERON:0001042!1.87e-07!24;UBERON:0008814!1.87e-07!24;UBERON:0009145!1.87e-07!24;UBERON:0002384!4.63e-07!46;UBERON:0003408!7.52e-07!24
|tfbs_overrepresentation_for_novel_motifs=0.762536,0.470303,0.695859,0.444236,0.191527,0.15366,0.214952,0.711075,0.247005,0.945047,0.542448,0.206436,0.22989,1.19059,0.0582501,0,0.977447,0.0483719,0.962407,0.305467,0.289278,0.495413,1.18809,0.741837,0.108863,0.243873,0.612988,0.966722,0.070875,0.978418,0.928995,0.460285,1.09732,0.0585697,0.464943,0.239233,1.99216,1.11373,0.336224,0.515604,0.0498798,0.942805,0.161515,0.0590946,1.20376,1.36273,0.309657,0.52593,0.0553373,0.916531,0.945634,1.34225,0.238206,0.586014,0.601849,0.648355,0.0764293,1.08868,0.575924,1.20474,0.442975,0.746278,0.502154,0.350689,0.667373,0.384144,0.727642,1.06142,0.438956,0.919268,0.0946191,0.240361,3.33162,0.632466,0.549252,0.504764,0.533375,0.300684,0.428247,0.295115,0.741934,1.00923,0.270104,0.0864064,0.5282,2.87087,0.874699,0.979381,0.842295,1.21975,0.793151,0.532634,0.471416,0.439258,0.594936,0.292027,0.0897681,1.19351,0.309859,0.204213,0.0440835,0.460042,0.570262,0.360414,0.359547,0.941628,0.409409,0.519389,1.0481,1.02158,0.115332,0.57187,0.296684,0.187937,0.799811,0.184628,1.9099,0.146927,0.375433,0.668337,0.637418,0.333667,0.245224,0.299972,0.851175,0.43141,0.220786,0.465518,0.726225,0.777839,0.554981,0.85315,0.698665,0.671684,0.820264,0.0109134,0.124253,0.162291,0.773792,1.58317,1.18855,0.732048,0.254204,0.469382,0.933035,0.161672,0.31213,1.54387,0.790363,0.429877,0.0451646,1.7765,0.587436,0.881834,0.670097,0.662158,0.264789,0.226926,0.756205,0.783526,0.782756,0.527439,0.431791,1.21191,0.351524,0.232792,0.0436468,0.205322,2.29643
}}
}}

Revision as of 18:12, 26 November 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr10:79785809..79785833,-p5@Pcsk4
Mm9::chr10:79785866..79785878,-p4@Pcsk4
Mm9::chr11:100721732..100721742,+p3@Stat5a
Mm9::chr11:23671230..23671264,-p6@Rel
Mm9::chr11:70051512..70051533,+p@chr11:70051512..70051533
+
Mm9::chr12:114067359..114067372,+p@chr12:114067359..114067372
+
Mm9::chr13:69673043..69673069,-p1@Papd7
Mm9::chr14:32308146..32308171,-p2@Mettl6
Mm9::chr17:57129821..57129833,+p@chr17:57129821..57129833
+
Mm9::chr19:10600074..10600095,+p@chr19:10600074..10600095
+
Mm9::chr19:53496109..53496137,+p@chr19:53496109..53496137
+
Mm9::chr1:174306731..174306755,+p2@Pigm
Mm9::chr2:132073579..132073599,+p@chr2:132073579..132073599
+
Mm9::chr3:87734359..87734371,+p4@Isg20l2
Mm9::chr3:90058266..90058285,+p3@Crtc2
Mm9::chr4:129488152..129488163,-p@chr4:129488152..129488163
-
Mm9::chr4:148478345..148478356,+p3@Dffa
Mm9::chr6:100621086..100621106,-p2@Shq1
Mm9::chr7:30638614..30638628,-p2@Zfp940
Mm9::chr7:71081571..71081581,+p@chr7:71081571..71081581
+
Mm9::chr9:120480504..120480537,-p@chr9:120480504..120480537
-
Mm9::chr9:20692745..20692756,+p4@Ppan


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0046544development of secondary male sexual characteristics0.0428620973140022
GO:0046543development of secondary female sexual characteristics0.0428620973140022
GO:0001560regulation of cell growth by extracellular stimulus0.0428620973140022
GO:0045136development of secondary sexual characteristics0.0428620973140022
GO:0001553luteinization0.0428620973140022
GO:0040008regulation of growth0.0428620973140022
GO:0001779natural killer cell differentiation0.0428620973140022
GO:0045647negative regulation of erythrocyte differentiation0.0428620973140022
GO:0045931positive regulation of progression through mitotic cell cycle0.0428620973140022
GO:0045579positive regulation of B cell differentiation0.0428620973140022
GO:0045885positive regulation of survival gene product activity0.0428620973140022
GO:0006309DNA fragmentation during apoptosis0.0428620973140022
GO:0019218regulation of steroid metabolic process0.0428620973140022
GO:0030856regulation of epithelial cell differentiation0.0428620973140022
GO:0000030mannosyltransferase activity0.0428620973140022
GO:0042104positive regulation of activated T cell proliferation0.0428620973140022
GO:0045086positive regulation of interleukin-2 biosynthetic process0.0428620973140022
GO:0006921cell structure disassembly during apoptosis0.0428620973140022
GO:0046006regulation of activated T cell proliferation0.0428620973140022
GO:0045577regulation of B cell differentiation0.0428620973140022
GO:0030262apoptotic nuclear changes0.0428620973140022
GO:0045646regulation of erythrocyte differentiation0.0428620973140022
GO:0031668cellular response to extracellular stimulus0.0428620973140022
GO:0019915sequestering of lipid0.0438073878106892
GO:0043029T cell homeostasis0.0438073878106892
GO:0045884regulation of survival gene product activity0.0455952132937886
GO:0045787positive regulation of progression through cell cycle0.0455952132937886
GO:0030101natural killer cell activation0.0455952132937886
GO:0045076regulation of interleukin-2 biosynthetic process0.0455952132937886
GO:0006308DNA catabolic process0.0455952132937886
GO:0050798activated T cell proliferation0.0455952132937886
GO:0004289subtilase activity0.0455952132937886
GO:0045621positive regulation of lymphocyte differentiation0.0455952132937886
GO:0009991response to extracellular stimulus0.0455952132937886
GO:0042094interleukin-2 biosynthetic process0.0455952132937886
GO:0007595lactation0.0455952132937886
GO:0032623interleukin-2 production0.0462434538972172
GO:0050729positive regulation of inflammatory response0.0462434538972172
GO:0031349positive regulation of defense response0.0462434538972172
GO:0019216regulation of lipid metabolic process0.0462434538972172
GO:0002260lymphocyte homeostasis0.0462434538972172
GO:0045638negative regulation of myeloid cell differentiation0.0462434538972172
GO:0051716cellular response to stimulus0.0462434538972172
GO:0007346regulation of progression through mitotic cell cycle0.0462434538972172
GO:0046489phosphoinositide biosynthetic process0.0462434538972172
GO:0006506GPI anchor biosynthetic process0.0462434538972172
GO:0042981regulation of apoptosis0.0462434538972172
GO:0043067regulation of programmed cell death0.0462434538972172
GO:0006505GPI anchor metabolic process0.0462434538972172
GO:0040018positive regulation of multicellular organism growth0.0462434538972172
GO:0030879mammary gland development0.0462434538972172
GO:0022411cellular component disassembly0.0462434538972172
GO:0045619regulation of lymphocyte differentiation0.0474254577769673
GO:0045927positive regulation of growth0.048877223103783
GO:0050871positive regulation of B cell activation0.048877223103783
GO:0006997nuclear organization and biogenesis0.048877223103783
GO:0001776leukocyte homeostasis0.048877223103783
GO:0046661male sex differentiation0.048877223103783
GO:0042102positive regulation of T cell proliferation0.048877223103783
GO:0007259JAK-STAT cascade0.048877223103783
GO:0048872homeostasis of number of cells0.048877223103783
GO:0031347regulation of defense response0.048877223103783
GO:0050727regulation of inflammatory response0.048877223103783
GO:0022601menstrual cycle phase0.048877223103783
GO:0009605response to external stimulus0.048877223103783
GO:0046474glycerophospholipid biosynthetic process0.048877223103783
GO:0022602menstrual cycle process0.048877223103783



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>



TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}