FF:10421-106C7: Difference between revisions
From FANTOM5_SSTAR
(Created page with "{{f5samples
|id=FF:10421-106C7
|name=adult T-cell leukemia cell line:ATN-1, biol_rep1
|sample_id=10421
|rna_tube_id=106C7
|rna_box=106
|rna_position=C7
|sample_cell_lot...") |
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005098 | ||
| | |DRA_sample_Accession_RNASeq=RNA-Seq@SAMD00005098 | ||
| | |accession_numbers=CAGE;DRX007824;DRR008696;DRZ000121;DRZ001506;DRZ011471;DRZ012856 | ||
| | |accession_numbers_RNASeq=RNA-Seq;DRX057121;DRR062880;DRZ007956 | ||
| | |ancestors_in_anatomy_facet= | ||
| | |ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0002371,CL:0000542,CL:0000219,CL:0000738,CL:0002087,CL:0002242,CL:0000255,CL:0000084 | ||
|ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:2531,DOID:0060058,DOID:14566,DOID:0060083,DOID:1240 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100737,FF:0101035,FF:0100104,FF:0103212,FF:0104049 | |||
|comment= | |||
|created_by= | |||
|creation_date= | |||
| | |data_phase=2 | ||
|datafreeze_phase=2 | |||
|def= | |||
| | |expression_enrichment_score=chr6:391743..391759,+!p1@IRF4!2.87!746.89!IRF4;;chr1:201979703..201979721,+!p2@ELF3!1.91!81.02!ELF3;;chr19:36204309..36204335,+!p1@ZBTB32!1.90!78.34!ZBTB32;;chr9:77112244..77112262,+!p1@RORB!1.84!76.23!RORB;;chr1:25256756..25256774,-!p1@RUNX3!1.79!109.77!RUNX3;;chr10:8096631..8096660,+!p1@GATA3!1.76!67.20!GATA3;;chr1:23857698..23857733,-!p1@E2F2!1.70!87.82!E2F2;;chr19:22193731..22193751,-!p1@ZNF208!1.69!47.59!ZNF208;;chr2:231090433..231090469,+!p1@SP140!1.62!40.90!SP140;;chr4:185395590..185395627,-!p3@IRF2!1.51!38.34!IRF2;;chr6:135502501..135502546,+!p1@MYB!1.51!37.78!MYB;;chr2:231090471..231090504,+!p2@SP140!1.50!30.54!SP140;;chr7:63505799..63505904,+!p1@ZNF727!1.48!28.86!ZNF727;;chr6:106534192..106534224,+!p1@PRDM1!1.46!77.12!PRDM1;;chr1:151319654..151319698,-!p2@RFX5!1.46!59.96!RFX5;;chr1:201979743..201979762,+!p1@ELF3!1.46!27.97!ELF3;;chr2:68592406..68592424,+!p1@PLEK!1.44!26.41!PLEK;;chr6:106534230..106534254,+!p2@PRDM1!1.41!60.74!PRDM1;;chr19:4153613..4153652,+!p1@CREB3L3!1.40!24.18!CREB3L3;;chr17:45810594..45810608,+!p1@TBX21!1.38!23.07!TBX21;;chr13:36788658..36788703,-!p2@CCDC169-SOHLH2,p2@SOHLH2!1.27!17.61!SOHLH2;;chr7:50343634..50343717,+!p2@IKZF1!1.23!16.05!IKZF1;;chr19:22235279..22235301,+!p1@ZNF257!1.22!29.09!ZNF257;;chr10:8096772..8096787,+!p2@GATA3!1.22!18.39!GATA3;;chr7:50348268..50348366,+!p4@IKZF1!1.22!15.60!IKZF1;;chr3:189349162..189349207,+!p2@TP63!1.19!14.60!TP63;;chr7:50344289..50344323,+!p1@IKZF1!1.18!14.15!IKZF1;;chr1:212873267..212873332,-!p1@BATF3!1.16!18.17!BATF3;;chr19:16435625..16435682,+!p1@KLF2!1.15!418.02!KLF2;;chr19:33793430..33793447,-!p1@CEBPA!1.15!54.83!CEBPA;;chr7:50344251..50344288,+!p3@IKZF1!1.15!13.26!IKZF1;;chr9:77112225..77112238,+!p2@RORB!1.14!12.93!RORB;;chr10:64134045..64134083,+!p3@ZNF365!1.14!12.82!ZNF365;;chr14:61116183..61116208,-!p1@SIX1!1.13!47.81!SIX1;;chr7:148581327..148581347,-!p2@EZH2!1.12!41.23!EZH2;;chr19:22398550..22398579,-!p@chr19:22398550..22398579,-!1.12!12.04!ZNF676;;chr10:104155480..104155534,+!p2@NFKB2!1.11!77.23!NFKB2;;chr2:231090344..231090361,-!p3@SP110!1.11!11.81!SP110;;chr19:22966893..22966924,-!p2@ZNF99!1.10!11.59!ZNF99;;chr18:77155922..77155939,+!p1@NFATC1!1.09!31.32!NFATC1;;chr19:22817119..22817145,+!p1@ZNF492!1.09!19.06!ZNF492;;chr7:26191809..26191890,+!p1@NFE2L3!1.08!54.94!NFE2L3;;chr19:22605136..22605154,-!p1@ZNF98!1.04!10.03!ZNF98;;chr19:22966925..22966958,-!p1@ZNF99!1.03!9.70!ZNF99;;chr5:176738887..176738934,-!p1@MXD3!1.02!65.08!MXD3;;chr10:104154246..104154347,+!p3@NFKB2!1.02!59.62!NFKB2;;chr2:68592394..68592405,+!p2@PLEK!1.02!9.36!PLEK;;chr17:17726907..17726958,-!p2@SREBF1!1.01!58.17!SREBF1;;chr8:72756063..72756125,-!p1@MSC!1.00!18.61!MSC;;chr6:135502408..135502459,+!p2@MYB!1.00!10.59!MYB;;chr1:44679370..44679422,+!p3@DMAP1!0.99!11.59!DMAP1;;chr7:35293685..35293718,-!p1@TBX20!0.99!8.69!TBX20;;chr16:29819558..29819572,+!p28@MAZ!0.99!8.69!MAZ;;chr17:46703942..46703964,-!p4@HOXB9!0.98!8.58!HOXB9;;chr12:48298785..48298828,-!p1@VDR!0.96!44.58!VDR;;chr4:185395633..185395651,-!p2@IRF2!0.96!13.37!IRF2;;chr12:56415246..56415286,+!p2@IKZF4!0.96!8.14!IKZF4;;chr19:22469236..22469266,+!p1@ZNF729!0.96!8.02!ZNF729;;chr2:97202480..97202499,+!p1@ARID5A!0.93!78.57!ARID5A;;chr1:212873084..212873137,-!p2@BATF3!0.93!7.47!BATF3;;chr8:72756667..72756736,-!p2@MSC!0.92!11.59!MSC;;chr1:23857325..23857416,-!p2@E2F2!0.92!8.58!E2F2;;chr20:56195474..56195506,-!p1@ZBP1!0.92!7.24!ZBP1;;chr4:299227..299272,-!p1@ZNF732!0.92!7.24!ZNF732;;chr19:22605097..22605121,-!p2@ZNF98!0.92!7.24!ZNF98;;chr7:148581360..148581425,-!p1@EZH2!0.91!36.55!EZH2;;chr14:75988771..75988826,+!p1@BATF!0.90!9.47!BATF;;chr10:64134120..64134183,+!p1@ZNF365!0.90!8.47!ZNF365;;chr7:64838786..64838809,+!p2@ZNF92!0.89!40.90!ZNF92;;chr4:81104895..81104920,+!p2@PRDM8!0.89!10.36!PRDM8;;chr10:8100691..8100732,+!p5@GATA3!0.89!6.80!GATA3;;chr10:8095593..8095625,+!p3@GATA3!0.88!7.80!GATA3;;chr17:41739283..41739297,-!p1@MEOX1!0.88!6.58!MEOX1;;chr17:46703212..46703238,-!p2@HOXB9!0.88!6.58!HOXB9;;chr4:53206..53260,+!p1@ZNF595,p1@ZNF718!0.87!64.53!ZNF595;;chr19:12405606..12405629,-!p2@ZNF44!0.87!13.04!ZNF44;;chr17:46703687..46703740,-!p1@HOXB9!0.87!6.46!HOXB9;;chr9:14308004..14308041,-!p14@NFIB!0.87!6.46!NFIB;;chr16:31885093..31885165,+!p1@ZNF267!0.86!100.97!ZNF267;;chr17:41623692..41623715,-!p1@ETV4!0.85!27.30!ETV4;;chr8:72756637..72756664,-!p3@MSC!0.85!6.91!MSC;;chr1:92951607..92951661,-!p1@GFI1!0.85!6.02!GFI1;;chr2:42721205..42721307,+!p4@MTA3!0.85!6.02!MTA3;;chr19:8578683..8578750,-!p2@ZNF414!0.84!13.26!ZNF414;;chr10:104155455..104155479,+!p1@NFKB2!0.83!91.50!NFKB2;;chr19:23433144..23433204,-!p1@ZNF724P!0.83!27.30!ZNF724P;;chr4:4861385..4861398,+!p1@MSX1!0.83!18.28!MSX1;;chr3:5021113..5021180,+!p1@BHLHE40!0.82!422.15!BHLHE40;;chrY:21906594..21906622,-!p1@KDM5D!0.81!5.46!KDM5D;;chr8:71053850..71053871,-!p22@NCOA2!0.81!5.46!NCOA2;;chr11:128563948..128564003,+!p1@FLI1!0.80!69.43!FLI1;;chr10:35484053..35484076,+!p1@CREM!0.80!13.93!CREM;;chr14:61116168..61116180,-!p2@SIX1!0.80!6.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r19:38085768..38085821,+!p1@ZNF540!0.18!1.23!ZNF540;;chr3:23986876..23986885,+!p4@NR1D2!0.18!1.11!NR1D2;;chr3:48282607..48282618,+!p3@ZNF589!0.18!1.00!ZNF589;;chr4:1873216..1873238,+!p5@WHSC1!0.18!1.00!WHSC1;;chr15:37392593..37392607,-!p13@MEIS2!0.18!0.78!MEIS2;;chr18:52989001..52989030,-!p10@TCF4!0.18!0.67!TCF4;;chr12:53847004..53847008,+!p13@PCBP2!0.18!0.67!PCBP2;;chr2:74374995..74375055,-!p1@BOLA3!0.17!59.29!BOLA3;;chr1:90460661..90460745,+!p1@ZNF326!0.17!37.67!ZNF326;;chr18:45457192..45457278,-!p1@SMAD2!0.17!22.18!SMAD2;;chr1:91487553..91487612,-!p1@ZNF644!0.17!21.84!ZNF644;;chr11:3400340..3400422,-!p1@ZNF195!0.17!20.39!ZNF195;;chr2:174828545..174828644,-!p1@SP3!0.17!19.95!SP3;;chr19:52772832..52772861,+!p1@ZNF766!0.17!12.93!ZNF766;;chr15:77197655..77197716,-!p1@SCAPER!0.17!11.48!SCAPER;;chr4:106068026..106068084,+!p1@TET2!0.17!11.26!TET2;;chr4:2263861..2263883,-!p2@MXD4!0.17!7.24!MXD4;;chr10:97889784..97889827,+!p1@ZNF518A!0.17!5.80!ZNF518A;;chr10:96122645..96122675,-!p2@NOC3L!0.17!5.57!NOC3L;;chr2:208394817..208394834,+!p3@CREB1!0.17!4.68!CREB1;;chr3:150126706..150126754,+!p5@TSC22D2!0.17!3.34!TSC22D2;;chr21:34144115..34144138,-!p2@GCFC1!0.17!3.12!GCFC1;;chr3:52001426..52001447,-!p3@PCBP4!0.17!3.01!PCBP4;;chr19:7069426..7069482,+!p2@ZNF557!0.17!2.90!ZNF557;;chr1:42800848..42800859,-!p2@FOXJ3!0.17!2.90!FOXJ3;;chr1:41174988..41175047,+!p4@NFYC!0.17!2.79!NFYC;;chr19:37178482..37178520,+!p1@ZNF567!0.17!2.79!ZNF567;;chr5:138647473..138647476,+!p6@MATR3!0.17!2.56!MATR3;;chr1:61548069..61548102,+!p3@NFIA!0.17!2.45!NFIA;;chr12:72058060..72058101,+!p5@THAP2!0.17!2.45!THAP2;;chr10:43932296..43932360,+!p1@ZNF487P!0.17!2.01!ZNF487P;;chr7:64126535..64126559,+!p2@ZNF107!0.17!2.01!ZNF107;;chr19:925727..925784,+!p3@ARID3A!0.17!2.01!ARID3A;;chr5:142784101..142784130,-!p4@NR3C1!0.17!1.67!NR3C1;;chr6:31869828..31869880,-!p1@ZBTB12!0.17!1.67!ZBTB12;;chr19:20150268..20150298,-!p2@ZNF682!0.17!1.67!ZNF682;;chr3:101395999..101396010,-!p3@ZBTB11!0.17!1.56!ZBTB11;;chr12:56575310..56575344,-!p3@SMARCC2!0.17!1.34!SMARCC2;;chr1:8763510..8763538,-!p15@RERE!0.17!1.34!RERE;;chr1:247095162..247095173,-!p3@AHCTF1!0.17!1.23!AHCTF1;;chr11:16759983..16760029,-!p2@SOX6!0.17!1.23!SOX6;;chr2:214016496..214016544,-!p5@IKZF2!0.17!1.00!IKZF2;;chr1:211432872..211432883,+!p7@RCOR3!0.17!0.89!RCOR3;;chr7:152133109..152133116,-!p2@MLL3!0.17!0.89!MLL3;;chr11:130184828..130184839,-!p7@ZBTB44!0.17!0.78!ZBTB44;;chr15:37392576..37392589,-!p12@MEIS2!0.17!0.78!MEIS2;;chr17:42295777..42295816,-!p7@UBTF!0.17!0.78!UBTF;;chr4:81104985..81105005,+!p4@PRDM8!0.17!0.78!PRDM8;;chr12:27485733..27485742,+!p5@ARNTL2!0.17!0.67!ARNTL2;;chr16:30407021..30407061,+!p3@ZNF48!0.17!0.67!ZNF48;;chr20:44600785..44600794,-!p7@ZNF335!0.17!0.67!ZNF335;;chr12:53835508..53835533,+!p1@PRR13,p2@PCBP2!0.16!98.85!PCBP2;;chr7:101459263..101459310,+!p1@CUX1!0.16!76.78!CUX1;;chr1:168195229..168195294,+!p1@SFT2D2,p1@TBX19!0.16!57.84!TBX19;;chr13:20357063..20357105,-!p1@PSPC1!0.16!42.01!PSPC1;;chr19:36705998..36706021,+!p2@ZNF146!0.16!18.28!ZNF146;;chr1:246729483..246729538,-!p2@TFB2M!0.16!11.81!TFB2M;;chr14:58765217..58765301,+!p1@ARID4A!0.16!11.14!ARID4A;;chr10:21823128..21823216,+!p1@MLLT10!0.16!11.03!MLLT10;;chr12:51566849..51566927,-!p1@TFCP2!0.16!10.36!TFCP2;;chr7:44925044..44925156,-!p1@PURB!0.16!9.81!PURB;;chr16:69419749..69419786,-!p2@TERF2!0.16!6.69!TERF2;;chr19:58662139..58662182,-!p1@ZNF329!0.16!5.57!ZNF329;;chr16:69419794..69419830,-!p3@TERF2!0.16!5.46!TERF2;;chr6:28092375..28092412,+!p1@ZSCAN16!0.16!4.68!ZSCAN16;;chr17:11900745..11900804,-!p1@ZNF18!0.16!4.23!ZNF18;;chr16:30569678..30569720,-!p1@ZNF764!0.16!3.90!ZNF764;;chr19:926001..926046,+!p1@ARID3A!0.16!3.79!ARID3A;;chr16:89787402..89787430,+!p2@ZNF276!0.16!3.34!ZNF276;;chr19:42636586..42636607,-!p1@POU2F2!0.16!2.79!POU2F2;; | ||
|ffid_belonging_in_development=CL:0000134,CL:0000051 | |||
| | |||
| | |||
| | |||
| | |||
| | |||
| | |||
| | |||
|fonse_cell_line=FF:0100104,FF:0101035 | |fonse_cell_line=FF:0100104,FF:0101035 | ||
|fonse_cell_line_closure=FF:0100104,FF:0101035 | |fonse_cell_line_closure=FF:0100104,FF:0101035 | ||
Line 67: | Line 42: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/adult%2520T-cell%2520leukemia%2520cell%2520line%253aATN-1.CNhs10738.10421-106C7.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/adult%2520T-cell%2520leukemia%2520cell%2520line%253aATN-1.CNhs10738.10421-106C7.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/adult%2520T-cell%2520leukemia%2520cell%2520line%253aATN-1.CNhs10738.10421-106C7.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/adult%2520T-cell%2520leukemia%2520cell%2520line%253aATN-1.CNhs10738.10421-106C7.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/adult%2520T-cell%2520leukemia%2520cell%2520line%253aATN-1.CNhs10738.10421-106C7.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10421-106C7 | |||
|is_a=EFO:0002091;;FF:0000210;;FF:0104049 | |||
|is_obsolete= | |||
|library_id=CNhs10738 | |||
|library_id_phase_based=2:CNhs10738 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10421 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10421 | |||
|name=adult T-cell leukemia cell line:ATN-1 | |||
|namespace=FANTOM5 | |||
|part_of= | |||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs10738,LSID692,release008,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,0.0901272703451053,0.125263300205101,-0.228945953098306,-0.219771910474392,0,0,0,0,0,0,0,0,0,0,0.444527898197577,0,0,-0.107435665240643,0,0,0,0.34512101429366,0.276817153886504,-0.0979578962680575,0,0,-0.132956589778862,0,0,0,0,0,0,0,0,0,0,0.0458873451077849,0,-0.149038287638542,0,0,0,0,0,0,0,0,0.0869689463907905,0,0,0,0.125263300205101,0,-0.0360986415435764,0,-0.0969923612426051,0,0,-0.097343627213097,0,0,0,0,0,0,0,0,0.0873862460237173,0,0.0873862460237173,0,0,0.0873862460237173,0,0,0,0,0,0,0,0,0.0458873451077849,-0.0476988691982421,-0.573895978850849,0,0,0,0.0458535532581336,-0.00705983013919385,0.0229436725538925,0,0.123743258673027,0,0.328744335683325,-0.058427065139727,0,0,0,0.0458873451077849,0,0,0,0,0,0,0,0,0,0,0,0,0,0.62435589570891,0.0458873451077849,0,0,-0.111604019374097,-0.232381280220199,0.0873862460237173,0,0,0,0,0.158806207253548 | |||
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| |||
|rna_box=106 | |||
|rna_catalog_number= | |||
|rna_concentration=1.29171 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=2.07 | |||
|rna_od260/280=2.11 | |||
|rna_position=C7 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=106C7 | |||
|rna_weight_ug=32.29275 | |||
|rnaseq_library_id=RDhi10064 | |||
|sample_age=47 | |||
|sample_category=cell lines | |||
|sample_cell_catalog=RCB1440 | |||
|sample_cell_line=ATN-1 | |||
|sample_cell_lot= | |||
|sample_cell_type=t cell | |||
|sample_collaboration=Yukio Nakamura (RIKEN BRC) | |||
|sample_company=RIKEN Bioresource centre | |||
|sample_description= | |||
|sample_dev_stage=47 year old adult | |||
|sample_disease=adult T-cell leukemia | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=unknown | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.61065876470306e-257!GO:0043227;membrane-bound organelle;2.25401260690789e-214!GO:0043231;intracellular membrane-bound organelle;4.66486702025719e-214!GO:0043226;organelle;2.01777171760922e-210!GO:0043229;intracellular organelle;5.46737316198153e-210!GO:0005737;cytoplasm;1.71019057417926e-166!GO:0044422;organelle part;4.90810223126466e-161!GO:0044446;intracellular organelle part;1.40105572006911e-159!GO:0032991;macromolecular complex;1.1764137803408e-120!GO:0044444;cytoplasmic part;8.88583583009079e-118!GO:0044237;cellular metabolic process;4.70680372775934e-107!GO:0005634;nucleus;2.22836703584669e-104!GO:0044238;primary metabolic process;3.41792271761269e-102!GO:0043170;macromolecule metabolic process;2.35512189083644e-96!GO:0030529;ribonucleoprotein complex;3.30228749069651e-93!GO:0044428;nuclear part;2.94993917736992e-92!GO:0003723;RNA binding;2.28744336754887e-84!GO:0043233;organelle lumen;1.85408785945402e-80!GO:0031974;membrane-enclosed lumen;1.85408785945402e-80!GO:0005739;mitochondrion;1.76124994964983e-68!GO:0043234;protein complex;1.28994943244081e-63!GO:0005515;protein binding;8.43313235437452e-62!GO:0043283;biopolymer metabolic process;2.0100259390351e-59!GO:0006412;translation;2.84350627769015e-58!GO:0006396;RNA processing;3.59484778722179e-58!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;3.20664121491166e-54!GO:0031981;nuclear lumen;8.0186091752586e-54!GO:0010467;gene expression;2.51747262388921e-51!GO:0005840;ribosome;1.75903641327413e-50!GO:0019538;protein metabolic process;2.77474759965462e-49!GO:0016071;mRNA metabolic process;6.25943361500931e-48!GO:0044429;mitochondrial part;2.30672572436389e-47!GO:0031090;organelle membrane;2.84731597923254e-47!GO:0031967;organelle envelope;1.43168538463545e-46!GO:0031975;envelope;3.57287612990609e-46!GO:0009059;macromolecule biosynthetic process;1.65437225997505e-45!GO:0044267;cellular protein metabolic process;8.10460708771507e-45!GO:0003735;structural constituent of ribosome;9.61384279085084e-45!GO:0006259;DNA metabolic process;1.69533190109866e-44!GO:0009058;biosynthetic process;5.21973455985062e-44!GO:0044260;cellular macromolecule metabolic process;7.52266222244532e-44!GO:0044249;cellular biosynthetic process;1.09358342481597e-43!GO:0016043;cellular component organization and biogenesis;3.75816796378913e-42!GO:0008380;RNA splicing;4.64491270032664e-42!GO:0006397;mRNA processing;6.01625091615413e-42!GO:0033036;macromolecule localization;3.97727079310143e-40!GO:0015031;protein transport;2.94915580417945e-39!GO:0006996;organelle organization and biogenesis;3.52468870499696e-39!GO:0005829;cytosol;1.8159015121984e-38!GO:0043228;non-membrane-bound organelle;3.86146247143078e-38!GO:0043232;intracellular non-membrane-bound organelle;3.86146247143078e-38!GO:0033279;ribosomal subunit;1.46632587835149e-37!GO:0045184;establishment of protein localization;1.54082340733885e-37!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.05648975808758e-36!GO:0046907;intracellular transport;3.19006469678366e-36!GO:0003676;nucleic acid binding;3.19006469678366e-36!GO:0008104;protein localization;7.45778329420409e-36!GO:0065003;macromolecular complex assembly;8.94617550773904e-36!GO:0000166;nucleotide binding;6.2275689792463e-33!GO:0005654;nucleoplasm;7.75631095752964e-33!GO:0005681;spliceosome;1.70200612356501e-31!GO:0007049;cell cycle;4.44254875446653e-31!GO:0022607;cellular component assembly;4.97936570588611e-31!GO:0005740;mitochondrial envelope;1.87959880539738e-30!GO:0006886;intracellular protein transport;3.43538760047366e-30!GO:0031966;mitochondrial membrane;1.06332727114704e-28!GO:0019866;organelle inner membrane;1.20162129075943e-28!GO:0005830;cytosolic ribosome (sensu Eukaryota);5.04831217257035e-28!GO:0005694;chromosome;1.72476007247206e-27!GO:0051649;establishment of cellular localization;5.58500182625207e-27!GO:0051641;cellular localization;1.18042430092417e-26!GO:0044445;cytosolic part;2.49895551871971e-26!GO:0006974;response to DNA damage stimulus;3.32868441886588e-26!GO:0005743;mitochondrial inner membrane;5.26351053378629e-26!GO:0032553;ribonucleotide binding;8.83631123011652e-25!GO:0032555;purine ribonucleotide binding;8.83631123011652e-25!GO:0044451;nucleoplasm part;8.83631123011652e-25!GO:0016070;RNA metabolic process;1.0014388501934e-24!GO:0017076;purine nucleotide binding;1.0447335323637e-24!GO:0022402;cell cycle process;1.35785279301732e-24!GO:0016462;pyrophosphatase activity;3.97235275729845e-24!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;4.60381064556992e-24!GO:0005524;ATP binding;4.72279592873398e-24!GO:0044427;chromosomal part;5.72888281549406e-24!GO:0016817;hydrolase activity, acting on acid anhydrides;6.54273944950918e-24!GO:0017111;nucleoside-triphosphatase activity;1.26721682203034e-23!GO:0006281;DNA repair;1.99129654380693e-23!GO:0032559;adenyl ribonucleotide binding;2.23706673777659e-23!GO:0030554;adenyl nucleotide binding;4.73701866091296e-23!GO:0005730;nucleolus;2.15754871105447e-22!GO:0000278;mitotic cell cycle;4.33947226830585e-22!GO:0022618;protein-RNA complex assembly;1.14760730788534e-21!GO:0051276;chromosome organization and biogenesis;2.86900702918978e-21!GO:0006119;oxidative phosphorylation;1.66916427746913e-20!GO:0016874;ligase activity;2.02748965680694e-20!GO:0000087;M phase of mitotic cell cycle;2.16386102089937e-20!GO:0012505;endomembrane system;2.16386102089937e-20!GO:0007067;mitosis;3.23948730157556e-20!GO:0015935;small ribosomal subunit;4.98451540239811e-20!GO:0031980;mitochondrial lumen;5.11154535955284e-20!GO:0005759;mitochondrial matrix;5.11154535955284e-20!GO:0006512;ubiquitin cycle;5.41863906398293e-20!GO:0044455;mitochondrial membrane part;6.31197076702065e-20!GO:0022403;cell cycle phase;1.01305139971248e-19!GO:0051301;cell division;1.11200679053097e-19!GO:0042623;ATPase activity, coupled;1.66549730117588e-18!GO:0015934;large ribosomal subunit;1.70057585107655e-18!GO:0016887;ATPase activity;3.28267679673653e-18!GO:0006260;DNA replication;3.55174067078434e-18!GO:0044265;cellular macromolecule catabolic process;7.69738906922516e-18!GO:0000279;M phase;9.47037188508572e-18!GO:0008134;transcription factor binding;9.91596651127763e-18!GO:0006457;protein folding;2.3307160724001e-17!GO:0008135;translation factor activity, nucleic acid binding;3.67431016245794e-17!GO:0000502;proteasome complex (sensu Eukaryota);5.25766507630789e-17!GO:0009719;response to endogenous stimulus;6.4820658995838e-17!GO:0005635;nuclear envelope;1.28764064455407e-16!GO:0016604;nuclear body;1.30659719092661e-16!GO:0042254;ribosome biogenesis and assembly;1.82835830824518e-16!GO:0005746;mitochondrial respiratory chain;3.78224944475757e-16!GO:0006325;establishment and/or maintenance of chromatin architecture;4.15329657418903e-16!GO:0000398;nuclear mRNA splicing, via spliceosome;1.24374534141973e-15!GO:0000375;RNA splicing, via transesterification reactions;1.24374534141973e-15!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;1.24374534141973e-15!GO:0006323;DNA packaging;1.74287266067968e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);2.44600826795407e-15!GO:0051603;proteolysis involved in cellular protein catabolic process;3.08799807935378e-15!GO:0019941;modification-dependent protein catabolic process;4.70395431271395e-15!GO:0043632;modification-dependent macromolecule catabolic process;4.70395431271395e-15!GO:0043412;biopolymer modification;4.98116817727884e-15!GO:0048770;pigment granule;5.14196292198614e-15!GO:0042470;melanosome;5.14196292198614e-15!GO:0005783;endoplasmic reticulum;6.39851432339162e-15!GO:0006605;protein targeting;6.50114393797052e-15!GO:0044257;cellular protein catabolic process;8.14931715909988e-15!GO:0006511;ubiquitin-dependent protein catabolic process;9.03456201269437e-15!GO:0012501;programmed cell death;1.32239169556466e-14!GO:0006915;apoptosis;1.3317026062389e-14!GO:0031965;nuclear membrane;1.52945669569718e-14!GO:0009057;macromolecule catabolic process;3.14694399416171e-14!GO:0044248;cellular catabolic process;4.86156183188407e-14!GO:0044432;endoplasmic reticulum part;5.90440262883839e-14!GO:0044453;nuclear membrane part;6.11983069674e-14!GO:0008219;cell death;6.70497188188498e-14!GO:0016265;death;6.70497188188498e-14!GO:0003743;translation initiation factor activity;8.29749694643612e-14!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;9.49334646896431e-14!GO:0043285;biopolymer catabolic process;1.0781205228598e-13!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.0781205228598e-13!GO:0005761;mitochondrial ribosome;1.35622478191962e-13!GO:0000313;organellar ribosome;1.35622478191962e-13!GO:0004386;helicase activity;3.83565082669458e-13!GO:0050136;NADH dehydrogenase (quinone) activity;3.83811521029071e-13!GO:0003954;NADH dehydrogenase activity;3.83811521029071e-13!GO:0008137;NADH dehydrogenase (ubiquinone) activity;3.83811521029071e-13!GO:0006333;chromatin assembly or disassembly;4.09087720258863e-13!GO:0051082;unfolded protein binding;5.33392955607618e-13!GO:0006464;protein modification process;5.76287782837445e-13!GO:0006413;translational initiation;1.18065413173405e-12!GO:0051186;cofactor metabolic process;1.31829054260207e-12!GO:0006399;tRNA metabolic process;1.37667558549906e-12!GO:0006913;nucleocytoplasmic transport;1.75776856906257e-12!GO:0016607;nuclear speck;1.92372132524283e-12!GO:0000785;chromatin;2.35700646779089e-12!GO:0042775;organelle ATP synthesis coupled electron transport;3.34677482085396e-12!GO:0042773;ATP synthesis coupled electron transport;3.34677482085396e-12!GO:0050657;nucleic acid transport;3.90333895964006e-12!GO:0051236;establishment of RNA localization;3.90333895964006e-12!GO:0050658;RNA transport;3.90333895964006e-12!GO:0051169;nuclear transport;4.30369808078141e-12!GO:0006403;RNA localization;5.57165315385464e-12!GO:0048193;Golgi vesicle transport;5.57165315385464e-12!GO:0008026;ATP-dependent helicase activity;6.0589538641297e-12!GO:0042175;nuclear envelope-endoplasmic reticulum network;9.61762143253763e-12!GO:0009259;ribonucleotide metabolic process;1.35464210894147e-11!GO:0043687;post-translational protein modification;1.47562702382137e-11!GO:0030964;NADH dehydrogenase complex (quinone);1.56809809573687e-11!GO:0045271;respiratory chain complex I;1.56809809573687e-11!GO:0005747;mitochondrial respiratory chain complex I;1.56809809573687e-11!GO:0005789;endoplasmic reticulum membrane;1.57016594689696e-11!GO:0005643;nuclear pore;1.81797634272491e-11!GO:0030163;protein catabolic process;2.55715198517995e-11!GO:0006163;purine nucleotide metabolic process;3.02150068656681e-11!GO:0003712;transcription cofactor activity;3.21062683390216e-11!GO:0006446;regulation of translational initiation;4.10952389443909e-11!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;4.36568910726734e-11!GO:0065004;protein-DNA complex assembly;6.03469704760954e-11!GO:0065002;intracellular protein transport across a membrane;7.41476337850708e-11!GO:0051726;regulation of cell cycle;8.43393858006789e-11!GO:0000074;regulation of progression through cell cycle;8.78213422440779e-11!GO:0006164;purine nucleotide biosynthetic process;1.2723420424469e-10!GO:0000775;chromosome, pericentric region;1.3182958643266e-10!GO:0006364;rRNA processing;1.49766822108532e-10!GO:0009260;ribonucleotide biosynthetic process;2.05588793921151e-10!GO:0009150;purine ribonucleotide metabolic process;2.19943623396424e-10!GO:0051028;mRNA transport;2.33646481462688e-10!GO:0016072;rRNA metabolic process;2.44309823097275e-10!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;3.97897831526363e-10!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;5.8566035343832e-10!GO:0004812;aminoacyl-tRNA ligase activity;5.8566035343832e-10!GO:0016875;ligase activity, forming carbon-oxygen bonds;5.8566035343832e-10!GO:0016568;chromatin modification;6.36602383820647e-10!GO:0043038;amino acid activation;7.57720795547051e-10!GO:0006418;tRNA aminoacylation for protein translation;7.57720795547051e-10!GO:0043039;tRNA aminoacylation;7.57720795547051e-10!GO:0006732;coenzyme metabolic process;8.92449050102597e-10!GO:0009152;purine ribonucleotide biosynthetic process;9.21873726660754e-10!GO:0046930;pore complex;1.14406254668139e-09!GO:0005794;Golgi apparatus;1.20454870264257e-09!GO:0016192;vesicle-mediated transport;1.35749078392691e-09!GO:0016787;hydrolase activity;1.38118831588027e-09!GO:0042981;regulation of apoptosis;1.88912050673144e-09!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;2.25883928657946e-09!GO:0005819;spindle;2.53087819682604e-09!GO:0043067;regulation of programmed cell death;2.85449810663603e-09!GO:0006461;protein complex assembly;2.9120261799765e-09!GO:0015630;microtubule cytoskeleton;3.07124058717004e-09!GO:0016779;nucleotidyltransferase activity;3.29745587495092e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;3.75953097487858e-09!GO:0019829;cation-transporting ATPase activity;4.22799807977618e-09!GO:0017038;protein import;4.49076958869057e-09!GO:0003697;single-stranded DNA binding;5.70028842888671e-09!GO:0006261;DNA-dependent DNA replication;6.75582960054307e-09!GO:0031497;chromatin assembly;6.75953301782294e-09!GO:0043566;structure-specific DNA binding;6.76740632745377e-09!GO:0006334;nucleosome assembly;7.78673768665525e-09!GO:0030532;small nuclear ribonucleoprotein complex;8.08281174101689e-09!GO:0015078;hydrogen ion transmembrane transporter activity;9.1677959708012e-09!GO:0016740;transferase activity;1.20483510291222e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;2.33151089751908e-08!GO:0009055;electron carrier activity;2.7919199411066e-08!GO:0006793;phosphorus metabolic process;2.97548159488552e-08!GO:0006796;phosphate metabolic process;2.97548159488552e-08!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;3.13231631300338e-08!GO:0007051;spindle organization and biogenesis;3.61312244858601e-08!GO:0009199;ribonucleoside triphosphate metabolic process;3.6178589086848e-08!GO:0000245;spliceosome assembly;3.79568620864447e-08!GO:0009141;nucleoside triphosphate metabolic process;3.79568620864447e-08!GO:0008639;small protein conjugating enzyme activity;4.91088957031316e-08!GO:0008565;protein transporter activity;4.92220433062065e-08!GO:0005839;proteasome core complex (sensu Eukaryota);5.43754006856486e-08!GO:0009142;nucleoside triphosphate biosynthetic process;6.57802740081052e-08!GO:0009201;ribonucleoside triphosphate biosynthetic process;6.57802740081052e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;7.49969563011485e-08!GO:0009144;purine nucleoside triphosphate metabolic process;7.49969563011485e-08!GO:0051246;regulation of protein metabolic process;7.89462439189314e-08!GO:0004842;ubiquitin-protein ligase activity;8.29198985533086e-08!GO:0009056;catabolic process;8.29552660856062e-08!GO:0019787;small conjugating protein ligase activity;8.34976120197301e-08!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.13624301207841e-07!GO:0015986;ATP synthesis coupled proton transport;1.26929857876604e-07!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.26929857876604e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;1.39542748219295e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;1.39542748219295e-07!GO:0009060;aerobic respiration;1.86436954738484e-07!GO:0015077;monovalent inorganic cation transmembrane transporter activity;2.52204351462911e-07!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;2.54456860042769e-07!GO:0015399;primary active transmembrane transporter activity;2.54456860042769e-07!GO:0051188;cofactor biosynthetic process;3.09307896742079e-07!GO:0004298;threonine endopeptidase activity;3.50629210010988e-07!GO:0007005;mitochondrion organization and biogenesis;3.53681656411169e-07!GO:0005813;centrosome;4.24731516808691e-07!GO:0016469;proton-transporting two-sector ATPase complex;7.02225260699953e-07!GO:0031202;RNA splicing factor activity, transesterification mechanism;7.06193306170806e-07!GO:0046034;ATP metabolic process;7.21919846965923e-07!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;8.60981627237374e-07!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;8.71656334791625e-07!GO:0000075;cell cycle checkpoint;9.58881332534712e-07!GO:0006754;ATP biosynthetic process;1.15340802361949e-06!GO:0006753;nucleoside phosphate metabolic process;1.15340802361949e-06!GO:0045333;cellular respiration;1.2158194800439e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;1.23356549626674e-06!GO:0016881;acid-amino acid ligase activity;1.32100121657803e-06!GO:0005815;microtubule organizing center;1.34405317268282e-06!GO:0016310;phosphorylation;1.36593053167492e-06!GO:0030120;vesicle coat;1.36593053167492e-06!GO:0030662;coated vesicle membrane;1.36593053167492e-06!GO:0045259;proton-transporting ATP synthase complex;1.46941968228816e-06!GO:0048475;coated membrane;1.92943589782249e-06!GO:0030117;membrane coat;1.92943589782249e-06!GO:0005793;ER-Golgi intermediate compartment;2.00614148950913e-06!GO:0032446;protein modification by small protein conjugation;2.04574830188697e-06!GO:0005657;replication fork;2.21852016336365e-06!GO:0003899;DNA-directed RNA polymerase activity;2.40027334963128e-06!GO:0051168;nuclear export;3.00201999556534e-06!GO:0005768;endosome;3.26764623633948e-06!GO:0000323;lytic vacuole;3.70861812346476e-06!GO:0005764;lysosome;3.70861812346476e-06!GO:0005773;vacuole;3.83865874708677e-06!GO:0016741;transferase activity, transferring one-carbon groups;3.97103171886385e-06!GO:0016567;protein ubiquitination;3.99897000888408e-06!GO:0003713;transcription coactivator activity;4.56682849195438e-06!GO:0016564;transcription repressor activity;4.60226139283176e-06!GO:0008168;methyltransferase activity;4.99454155938651e-06!GO:0007249;I-kappaB kinase/NF-kappaB cascade;5.25245345505786e-06!GO:0006613;cotranslational protein targeting to membrane;5.3756985926685e-06!GO:0003724;RNA helicase activity;5.9936929953064e-06!GO:0043492;ATPase activity, coupled to movement of substances;6.54396652265748e-06!GO:0008094;DNA-dependent ATPase activity;6.78368471302188e-06!GO:0006888;ER to Golgi vesicle-mediated transport;7.22668181274048e-06!GO:0006752;group transfer coenzyme metabolic process;7.38802588392322e-06!GO:0006606;protein import into nucleus;8.12120063519599e-06!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;9.24724155463469e-06!GO:0051170;nuclear import;9.38987255568707e-06!GO:0009117;nucleotide metabolic process;1.11696353721631e-05!GO:0016563;transcription activator activity;1.19072021656508e-05!GO:0006366;transcription from RNA polymerase II promoter;1.21273524462661e-05!GO:0019222;regulation of metabolic process;1.26603415736722e-05!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;1.37482152787893e-05!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;1.38207898873456e-05!GO:0009108;coenzyme biosynthetic process;1.41625809160689e-05!GO:0006099;tricarboxylic acid cycle;1.4512011623834e-05!GO:0046356;acetyl-CoA catabolic process;1.4512011623834e-05!GO:0016363;nuclear matrix;1.7331260173491e-05!GO:0019867;outer membrane;1.75358958855345e-05!GO:0031968;organelle outer membrane;2.04619747787624e-05!GO:0007059;chromosome segregation;2.27109299109816e-05!GO:0051325;interphase;2.60728047924218e-05!GO:0006310;DNA recombination;2.72862510022822e-05!GO:0005798;Golgi-associated vesicle;2.84364016330858e-05!GO:0050794;regulation of cellular process;3.12471225246821e-05!GO:0000776;kinetochore;3.4748708291848e-05!GO:0006084;acetyl-CoA metabolic process;3.55429592401077e-05!GO:0031324;negative regulation of cellular metabolic process;3.56094172019615e-05!GO:0005741;mitochondrial outer membrane;3.89248258557817e-05!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;4.23349224075581e-05!GO:0006302;double-strand break repair;4.50533454288421e-05!GO:0006417;regulation of translation;4.83504629384857e-05!GO:0005770;late endosome;5.73572652076907e-05!GO:0005762;mitochondrial large ribosomal subunit;6.92823519435344e-05!GO:0000315;organellar large ribosomal subunit;6.92823519435344e-05!GO:0051329;interphase of mitotic cell cycle;7.42121830748366e-05!GO:0019843;rRNA binding;8.55633280601806e-05!GO:0006612;protein targeting to membrane;8.55633280601806e-05!GO:0043069;negative regulation of programmed cell death;8.58359304090986e-05!GO:0000079;regulation of cyclin-dependent protein kinase activity;8.58359304090986e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;9.98894286179676e-05!GO:0043066;negative regulation of apoptosis;0.000104662296575757!GO:0009109;coenzyme catabolic process;0.000113761559724062!GO:0006916;anti-apoptosis;0.000121899966233253!GO:0000151;ubiquitin ligase complex;0.000131253149580726!GO:0043623;cellular protein complex assembly;0.000136841793193957!GO:0007052;mitotic spindle organization and biogenesis;0.000144822238355365!GO:0008033;tRNA processing;0.00014763575305794!GO:0008186;RNA-dependent ATPase activity;0.000163119843886408!GO:0004518;nuclease activity;0.000164390516002579!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00017584293898987!GO:0003714;transcription corepressor activity;0.000177085335999372!GO:0043021;ribonucleoprotein binding;0.000178004321792122!GO:0044431;Golgi apparatus part;0.000193651695990787!GO:0003729;mRNA binding;0.000208517559780819!GO:0048523;negative regulation of cellular process;0.000209229110631557!GO:0004527;exonuclease activity;0.000220137534221476!GO:0043065;positive regulation of apoptosis;0.000223213004212238!GO:0003684;damaged DNA binding;0.000224717687245928!GO:0005667;transcription factor complex;0.000225345833304337!GO:0031323;regulation of cellular metabolic process;0.000229400572580103!GO:0051187;cofactor catabolic process;0.000230333778517372!GO:0003682;chromatin binding;0.000231950923727587!GO:0005885;Arp2/3 protein complex;0.000234718426383876!GO:0000786;nucleosome;0.000234718426383876!GO:0006402;mRNA catabolic process;0.000267410834306457!GO:0031326;regulation of cellular biosynthetic process;0.000272023629733095!GO:0003690;double-stranded DNA binding;0.000274564393879553!GO:0019899;enzyme binding;0.000283996704182269!GO:0000314;organellar small ribosomal subunit;0.000284474474436526!GO:0005763;mitochondrial small ribosomal subunit;0.000284474474436526!GO:0043068;positive regulation of programmed cell death;0.0002890124149666!GO:0008654;phospholipid biosynthetic process;0.00029022656608682!GO:0007017;microtubule-based process;0.000290524588864667!GO:0051427;hormone receptor binding;0.000292450141165893!GO:0044452;nucleolar part;0.000294675365851557!GO:0016853;isomerase activity;0.000294835507060552!GO:0065009;regulation of a molecular function;0.000294835507060552!GO:0003924;GTPase activity;0.000300517010441926!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000313743284806067!GO:0003678;DNA helicase activity;0.000333259593487433!GO:0006383;transcription from RNA polymerase III promoter;0.000339242992225824!GO:0019752;carboxylic acid metabolic process;0.000351149695133689!GO:0007243;protein kinase cascade;0.000360445599181614!GO:0009165;nucleotide biosynthetic process;0.000360782857399082!GO:0000049;tRNA binding;0.000370103312908177!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000376056880270811!GO:0006626;protein targeting to mitochondrion;0.000381284391126824!GO:0006414;translational elongation;0.000392059278903783!GO:0006082;organic acid metabolic process;0.000392284450896192!GO:0009112;nucleobase metabolic process;0.000392541129390953!GO:0006091;generation of precursor metabolites and energy;0.000407617345887134!GO:0007088;regulation of mitosis;0.000414845342640511!GO:0015992;proton transport;0.00042052898335682!GO:0006818;hydrogen transport;0.000420943728249434!GO:0030658;transport vesicle membrane;0.000435807867479451!GO:0045786;negative regulation of progression through cell cycle;0.000436669200252485!GO:0043681;protein import into mitochondrion;0.000439609878549855!GO:0004004;ATP-dependent RNA helicase activity;0.000465414860919284!GO:0006401;RNA catabolic process;0.00047207085726849!GO:0009892;negative regulation of metabolic process;0.00047207085726849!GO:0044440;endosomal part;0.000479902339367915!GO:0010008;endosome membrane;0.000479902339367915!GO:0006650;glycerophospholipid metabolic process;0.000553387368376733!GO:0032508;DNA duplex unwinding;0.000556462777807746!GO:0032392;DNA geometric change;0.000556462777807746!GO:0022890;inorganic cation transmembrane transporter activity;0.000561176487119053!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000562616948267706!GO:0035257;nuclear hormone receptor binding;0.000571460550806893!GO:0030384;phosphoinositide metabolic process;0.000600067636346634!GO:0004674;protein serine/threonine kinase activity;0.000608974553025621!GO:0042613;MHC class II protein complex;0.000620787503427062!GO:0045454;cell redox homeostasis;0.000624047603785691!GO:0030880;RNA polymerase complex;0.00067786739354272!GO:0015631;tubulin binding;0.000703877454539382!GO:0042802;identical protein binding;0.000732484179977396!GO:0000287;magnesium ion binding;0.000758669153109118!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000758669153109118!GO:0006405;RNA export from nucleus;0.000773737671386906!GO:0007093;mitotic cell cycle checkpoint;0.000812391475601885!GO:0006520;amino acid metabolic process;0.000816031967597278!GO:0005874;microtubule;0.000834967578919411!GO:0051052;regulation of DNA metabolic process;0.000877065440351973!GO:0006350;transcription;0.000885112866043973!GO:0005637;nuclear inner membrane;0.000922283092524049!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00100453623062136!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00100453623062136!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00100453623062136!GO:0006917;induction of apoptosis;0.00100833655144274!GO:0031072;heat shock protein binding;0.00102371646437154!GO:0006891;intra-Golgi vesicle-mediated transport;0.00104199741216739!GO:0005525;GTP binding;0.00106469448794804!GO:0006268;DNA unwinding during replication;0.00107102919591106!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.00109730938748204!GO:0005684;U2-dependent spliceosome;0.00111093390279476!GO:0046483;heterocycle metabolic process;0.00112622574102307!GO:0005048;signal sequence binding;0.0012538310615075!GO:0031988;membrane-bound vesicle;0.00127947850006725!GO:0006352;transcription initiation;0.00128059369184976!GO:0030660;Golgi-associated vesicle membrane;0.00129182979197601!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00137386600738094!GO:0000428;DNA-directed RNA polymerase complex;0.00137386600738094!GO:0012502;induction of programmed cell death;0.00137419130910787!GO:0051252;regulation of RNA metabolic process;0.00142235054375914!GO:0048500;signal recognition particle;0.00158426082502402!GO:0031982;vesicle;0.00164729829128792!GO:0000910;cytokinesis;0.00179028697225398!GO:0008234;cysteine-type peptidase activity;0.00180661859132723!GO:0042611;MHC protein complex;0.00180982247272681!GO:0051920;peroxiredoxin activity;0.00193269991208138!GO:0048519;negative regulation of biological process;0.00202294746962245!GO:0030867;rough endoplasmic reticulum membrane;0.00206702664879804!GO:0009889;regulation of biosynthetic process;0.00213607147562258!GO:0046489;phosphoinositide biosynthetic process;0.00216392193265553!GO:0000819;sister chromatid segregation;0.00216392193265553!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00221515658047004!GO:0015002;heme-copper terminal oxidase activity;0.00221515658047004!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00221515658047004!GO:0004129;cytochrome-c oxidase activity;0.00221515658047004!GO:0031124;mRNA 3'-end processing;0.00222471649597707!GO:0016023;cytoplasmic membrane-bound vesicle;0.00223631468962467!GO:0006289;nucleotide-excision repair;0.00227309281443906!GO:0048471;perinuclear region of cytoplasm;0.00230561314021651!GO:0000070;mitotic sister chromatid segregation;0.00234014218604991!GO:0000139;Golgi membrane;0.00243484310844191!GO:0046474;glycerophospholipid biosynthetic process;0.00243484310844191!GO:0016197;endosome transport;0.00243484310844191!GO:0016491;oxidoreductase activity;0.00245345440887201!GO:0000922;spindle pole;0.00248731908684456!GO:0009124;nucleoside monophosphate biosynthetic process;0.00248731908684456!GO:0009123;nucleoside monophosphate metabolic process;0.00248731908684456!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00252648795301789!GO:0008632;apoptotic program;0.00259155085405588!GO:0010468;regulation of gene expression;0.00277634295265607!GO:0006839;mitochondrial transport;0.00278569345055135!GO:0016251;general RNA polymerase II transcription factor activity;0.00279735157772836!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00311046330308625!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00311046330308625!GO:0007006;mitochondrial membrane organization and biogenesis;0.00328781753836092!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0033479809850124!GO:0045047;protein targeting to ER;0.0033479809850124!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.0033593732654063!GO:0007010;cytoskeleton organization and biogenesis;0.00336565949281379!GO:0008312;7S RNA binding;0.00339596054287569!GO:0031410;cytoplasmic vesicle;0.00349031229301859!GO:0043596;nuclear replication fork;0.00377780178700463!GO:0006144;purine base metabolic process;0.00384556729565382!GO:0005876;spindle microtubule;0.00384559876813605!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;0.00384612341864278!GO:0016859;cis-trans isomerase activity;0.00391399695245404!GO:0016481;negative regulation of transcription;0.00396690232101867!GO:0051087;chaperone binding;0.00417543021922095!GO:0031123;RNA 3'-end processing;0.00418890336437953!GO:0008276;protein methyltransferase activity;0.00432902827294626!GO:0016272;prefoldin complex;0.0045603596398252!GO:0031902;late endosome membrane;0.0045603596398252!GO:0030118;clathrin coat;0.0045735622891493!GO:0032259;methylation;0.0046721620250842!GO:0006519;amino acid and derivative metabolic process;0.00481915703762519!GO:0006595;polyamine metabolic process;0.00484752516871432!GO:0005788;endoplasmic reticulum lumen;0.00487079503166466!GO:0000228;nuclear chromosome;0.0049114375268699!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00504866326882946!GO:0003711;transcription elongation regulator activity;0.00508724834488303!GO:0008022;protein C-terminus binding;0.00513414299138042!GO:0000059;protein import into nucleus, docking;0.00516339583271808!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00553326519145176!GO:0032200;telomere organization and biogenesis;0.00567486484179252!GO:0000723;telomere maintenance;0.00567486484179252!GO:0043488;regulation of mRNA stability;0.00568050861403511!GO:0043487;regulation of RNA stability;0.00568050861403511!GO:0005769;early endosome;0.00570810410107687!GO:0051789;response to protein stimulus;0.00583137521387326!GO:0006986;response to unfolded protein;0.00583137521387326!GO:0008139;nuclear localization sequence binding;0.00592330984606055!GO:0009161;ribonucleoside monophosphate metabolic process;0.00619402996820168!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.00619402996820168!GO:0000082;G1/S transition of mitotic cell cycle;0.00647484454036401!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00652791195127391!GO:0006284;base-excision repair;0.00673163397279889!GO:0004860;protein kinase inhibitor activity;0.00676703381239404!GO:0006506;GPI anchor biosynthetic process;0.0067755854805957!GO:0030176;integral to endoplasmic reticulum membrane;0.00689029005241309!GO:0005758;mitochondrial intermembrane space;0.00700101684265451!GO:0046966;thyroid hormone receptor binding;0.00708200104767593!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00719763826372492!GO:0006505;GPI anchor metabolic process;0.00728944901469662!GO:0004003;ATP-dependent DNA helicase activity;0.00749472410642141!GO:0006730;one-carbon compound metabolic process;0.00797039565261305!GO:0045045;secretory pathway;0.008009527687998!GO:0005669;transcription factor TFIID complex;0.00802363096130366!GO:0005791;rough endoplasmic reticulum;0.00819716359996116!GO:0006275;regulation of DNA replication;0.00832843965074154!GO:0051539;4 iron, 4 sulfur cluster binding;0.00835753265118863!GO:0030663;COPI coated vesicle membrane;0.00843418095857696!GO:0030126;COPI vesicle coat;0.00843418095857696!GO:0003725;double-stranded RNA binding;0.00843434439406681!GO:0008250;oligosaccharyl transferase complex;0.00843864608499835!GO:0030133;transport vesicle;0.00845550308968119!GO:0006376;mRNA splice site selection;0.00852411581198564!GO:0000389;nuclear mRNA 3'-splice site recognition;0.00852411581198564!GO:0006338;chromatin remodeling;0.0086776809250518!GO:0015980;energy derivation by oxidation of organic compounds;0.00884329064553127!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.00893348177812121!GO:0005832;chaperonin-containing T-complex;0.00896095299302952!GO:0032561;guanyl ribonucleotide binding;0.0091769641475743!GO:0019001;guanyl nucleotide binding;0.0091769641475743!GO:0050662;coenzyme binding;0.00925087047902831!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00932734334274256!GO:0006611;protein export from nucleus;0.00958268520722591!GO:0043022;ribosome binding;0.00975675892494291!GO:0005765;lysosomal membrane;0.00999870787638077!GO:0004576;oligosaccharyl transferase activity;0.0103162040017621!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0106650486154625!GO:0042770;DNA damage response, signal transduction;0.0106922190074489!GO:0006270;DNA replication initiation;0.0107861799049648!GO:0044438;microbody part;0.0108988397514505!GO:0044439;peroxisomal part;0.0108988397514505!GO:0050789;regulation of biological process;0.0109005687013822!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0110968974361394!GO:0005996;monosaccharide metabolic process;0.0115652373939305!GO:0000152;nuclear ubiquitin ligase complex;0.0123683575935221!GO:0030125;clathrin vesicle coat;0.0123683575935221!GO:0030665;clathrin coated vesicle membrane;0.0123683575935221!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.012395229918075!GO:0008637;apoptotic mitochondrial changes;0.0124047543581672!GO:0031570;DNA integrity checkpoint;0.0124074719509678!GO:0006497;protein amino acid lipidation;0.0124555289801201!GO:0005774;vacuolar membrane;0.0124649197600227!GO:0019882;antigen processing and presentation;0.0124968754349011!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0125700714165975!GO:0019318;hexose metabolic process;0.0128010946152864!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.0129334227263994!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.0129334227263994!GO:0009126;purine nucleoside monophosphate metabolic process;0.0129334227263994!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.0129334227263994!GO:0031903;microbody membrane;0.0129682990254816!GO:0005778;peroxisomal membrane;0.0129682990254816!GO:0006007;glucose catabolic process;0.013009362619938!GO:0008408;3'-5' exonuclease activity;0.0131054326449363!GO:0016281;eukaryotic translation initiation factor 4F complex;0.0132695004097874!GO:0046467;membrane lipid biosynthetic process;0.0132695004097874!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0133957599406609!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0134322540393816!GO:0009116;nucleoside metabolic process;0.0137493197109792!GO:0006672;ceramide metabolic process;0.0140207759569484!GO:0032774;RNA biosynthetic process;0.014130611331267!GO:0018196;peptidyl-asparagine modification;0.0141412215799813!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0141412215799813!GO:0008017;microtubule binding;0.0143088897922412!GO:0032940;secretion by cell;0.014447389535507!GO:0043284;biopolymer biosynthetic process;0.0147114804880755!GO:0048487;beta-tubulin binding;0.0147578856158557!GO:0031970;organelle envelope lumen;0.0147629142939761!GO:0005521;lamin binding;0.0148450122156484!GO:0031252;leading edge;0.0149272520310953!GO:0051053;negative regulation of DNA metabolic process;0.015097216286737!GO:0016584;nucleosome positioning;0.0152585946989577!GO:0003746;translation elongation factor activity;0.015385820240914!GO:0000781;chromosome, telomeric region;0.0153969170617987!GO:0018193;peptidyl-amino acid modification;0.0155517384289339!GO:0019210;kinase inhibitor activity;0.0155517384289339!GO:0005869;dynactin complex;0.0158818301677201!GO:0030137;COPI-coated vesicle;0.0162680337169698!GO:0044262;cellular carbohydrate metabolic process;0.0162680337169698!GO:0046365;monosaccharide catabolic process;0.0164558619254982!GO:0051098;regulation of binding;0.0164617937279759!GO:0009119;ribonucleoside metabolic process;0.0165792490135249!GO:0006220;pyrimidine nucleotide metabolic process;0.0168277271438415!GO:0006351;transcription, DNA-dependent;0.0168277271438415!GO:0004532;exoribonuclease activity;0.0171772404438707!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0171772404438707!GO:0030140;trans-Golgi network transport vesicle;0.0171810799544668!GO:0006378;mRNA polyadenylation;0.0172508956607778!GO:0009303;rRNA transcription;0.0174495263892424!GO:0008538;proteasome activator activity;0.0174841796056606!GO:0043414;biopolymer methylation;0.0178065325176774!GO:0008180;signalosome;0.0180752410569793!GO:0009451;RNA modification;0.0184316813972756!GO:0030496;midbody;0.0188409365134764!GO:0046979;TAP2 binding;0.0190061682289707!GO:0046977;TAP binding;0.0190061682289707!GO:0046978;TAP1 binding;0.0190061682289707!GO:0043601;nuclear replisome;0.0190061682289707!GO:0030894;replisome;0.0190061682289707!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0195943235660101!GO:0003677;DNA binding;0.0197352016067405!GO:0050790;regulation of catalytic activity;0.0198245873234012!GO:0008320;protein transmembrane transporter activity;0.0199321922786228!GO:0033116;ER-Golgi intermediate compartment membrane;0.0200077688046241!GO:0019206;nucleoside kinase activity;0.0200313103891103!GO:0019238;cyclohydrolase activity;0.0206727974487899!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0207106690844826!GO:0016311;dephosphorylation;0.0208140763821731!GO:0030130;clathrin coat of trans-Golgi network vesicle;0.0208140763821731!GO:0012510;trans-Golgi network transport vesicle membrane;0.0208140763821731!GO:0030134;ER to Golgi transport vesicle;0.0210552460596153!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.021143666071879!GO:0046164;alcohol catabolic process;0.0212015935208236!GO:0046983;protein dimerization activity;0.0213382419589889!GO:0019783;small conjugating protein-specific protease activity;0.0217830066366247!GO:0042393;histone binding;0.0219500905767209!GO:0008610;lipid biosynthetic process;0.0220673461886537!GO:0006118;electron transport;0.0220924168533793!GO:0035267;NuA4 histone acetyltransferase complex;0.0222250161456508!GO:0043621;protein self-association;0.0224041388268261!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.0225168053815372!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0229119988498878!GO:0010257;NADH dehydrogenase complex assembly;0.0229119988498878!GO:0033108;mitochondrial respiratory chain complex assembly;0.0229119988498878!GO:0051540;metal cluster binding;0.0235141825064828!GO:0051536;iron-sulfur cluster binding;0.0235141825064828!GO:0044437;vacuolar part;0.0237548753708237!GO:0051235;maintenance of localization;0.0237617448459947!GO:0000339;RNA cap binding;0.0241285688241201!GO:0000726;non-recombinational repair;0.0244617894677448!GO:0043189;H4/H2A histone acetyltransferase complex;0.0252231512240699!GO:0022884;macromolecule transmembrane transporter activity;0.0252282595995975!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0252282595995975!GO:0022406;membrane docking;0.0253852242040801!GO:0048278;vesicle docking;0.0253852242040801!GO:0019320;hexose catabolic process;0.0256208925954286!GO:0009308;amine metabolic process;0.0259488232777869!GO:0006807;nitrogen compound metabolic process;0.0260977842326268!GO:0040029;regulation of gene expression, epigenetic;0.0261921884282958!GO:0000725;recombinational repair;0.0265083922971569!GO:0000724;double-strand break repair via homologous recombination;0.0265083922971569!GO:0016791;phosphoric monoester hydrolase activity;0.0269867685650008!GO:0030433;ER-associated protein catabolic process;0.0270323711219516!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0270323711219516!GO:0006406;mRNA export from nucleus;0.0271151840331469!GO:0000077;DNA damage checkpoint;0.0271256940162098!GO:0046112;nucleobase biosynthetic process;0.0272246187320207!GO:0031577;spindle checkpoint;0.0274243343605871!GO:0004843;ubiquitin-specific protease activity;0.0274452976671229!GO:0005663;DNA replication factor C complex;0.0278343754637128!GO:0030374;ligand-dependent nuclear receptor transcription coactivator activity;0.0279261125847509!GO:0030127;COPII vesicle coat;0.0280868468174589!GO:0012507;ER to Golgi transport vesicle membrane;0.0280868468174589!GO:0016126;sterol biosynthetic process;0.0282758598597531!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0282833772396272!GO:0005680;anaphase-promoting complex;0.0289279937989971!GO:0006213;pyrimidine nucleoside metabolic process;0.029105471992148!GO:0019976;interleukin-2 binding;0.0296020850895786!GO:0004911;interleukin-2 receptor activity;0.0296020850895786!GO:0046519;sphingoid metabolic process;0.0298291010323674!GO:0009967;positive regulation of signal transduction;0.0298392760338929!GO:0005092;GDP-dissociation inhibitor activity;0.0298392760338929!GO:0000178;exosome (RNase complex);0.0299417581408173!GO:0030119;AP-type membrane coat adaptor complex;0.030174211567982!GO:0042158;lipoprotein biosynthetic process;0.030174211567982!GO:0000096;sulfur amino acid metabolic process;0.0303595793316327!GO:0009081;branched chain family amino acid metabolic process;0.0303595793316327!GO:0007034;vacuolar transport;0.0305810494627473!GO:0000792;heterochromatin;0.0306770328425033!GO:0016790;thiolester hydrolase activity;0.0307800525022101!GO:0005784;translocon complex;0.0308130657201441!GO:0003887;DNA-directed DNA polymerase activity;0.0308260608839432!GO:0006950;response to stress;0.0309737460543114!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.0309737460543114!GO:0016301;kinase activity;0.0311687629295618!GO:0031647;regulation of protein stability;0.0319166712536985!GO:0008097;5S rRNA binding;0.0319245715222208!GO:0006695;cholesterol biosynthetic process;0.0319854423543232!GO:0051287;NAD binding;0.0325126513532676!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0327413323544523!GO:0006904;vesicle docking during exocytosis;0.0333826020453332!GO:0000062;acyl-CoA binding;0.0334571834387745!GO:0000123;histone acetyltransferase complex;0.0335780040329674!GO:0030308;negative regulation of cell growth;0.0339616611638848!GO:0017134;fibroblast growth factor binding;0.0339616611638848!GO:0019901;protein kinase binding;0.033991638336289!GO:0006643;membrane lipid metabolic process;0.0344307147901847!GO:0005652;nuclear lamina;0.0345862338891226!GO:0006779;porphyrin biosynthetic process;0.0346718170046455!GO:0033014;tetrapyrrole biosynthetic process;0.0346718170046455!GO:0045792;negative regulation of cell size;0.0348634392932776!GO:0007021;tubulin folding;0.0353954830803576!GO:0004721;phosphoprotein phosphatase activity;0.0357188846101941!GO:0030132;clathrin coat of coated pit;0.0357188846101941!GO:0016788;hydrolase activity, acting on ester bonds;0.0357901303768634!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0359881674978356!GO:0008536;Ran GTPase binding;0.0359881674978356!GO:0008287;protein serine/threonine phosphatase complex;0.0360705993705618!GO:0046822;regulation of nucleocytoplasmic transport;0.0365441929193031!GO:0000793;condensed chromosome;0.0369439377865433!GO:0031625;ubiquitin protein ligase binding;0.0369635693458394!GO:0051338;regulation of transferase activity;0.0370711861762943!GO:0006740;NADPH regeneration;0.0370711861762943!GO:0006098;pentose-phosphate shunt;0.0370711861762943!GO:0004523;ribonuclease H activity;0.0372938998766946!GO:0051090;regulation of transcription factor activity;0.0376746019588379!GO:0047485;protein N-terminus binding;0.0380371807613661!GO:0042289;MHC class II protein binding;0.0381387519904188!GO:0003988;acetyl-CoA C-acyltransferase activity;0.0385082142791977!GO:0051881;regulation of mitochondrial membrane potential;0.0393990765140526!GO:0004221;ubiquitin thiolesterase activity;0.0395514341337897!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0403736903409762!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0404290709185816!GO:0030503;regulation of cell redox homeostasis;0.0404743098731333!GO:0008537;proteasome activator complex;0.041520442749559!GO:0046128;purine ribonucleoside metabolic process;0.0417361199638894!GO:0042278;purine nucleoside metabolic process;0.0417361199638894!GO:0016585;chromatin remodeling complex;0.0419449547903823!GO:0008156;negative regulation of DNA replication;0.042847576590634!GO:0006914;autophagy;0.042847576590634!GO:0006783;heme biosynthetic process;0.0438125223604115!GO:0019900;kinase binding;0.0441267844574266!GO:0008629;induction of apoptosis by intracellular signals;0.0446740035960473!GO:0006644;phospholipid metabolic process;0.0446946695750164!GO:0006892;post-Golgi vesicle-mediated transport;0.0446946695750164!GO:0046426;negative regulation of JAK-STAT cascade;0.0452682121056064!GO:0044450;microtubule organizing center part;0.045494006947981!GO:0032404;mismatch repair complex binding;0.0456462979045204!GO:0000209;protein polyubiquitination;0.0459418931008004!GO:0006778;porphyrin metabolic process;0.0459418931008004!GO:0033013;tetrapyrrole metabolic process;0.0459418931008004!GO:0030508;thiol-disulfide exchange intermediate activity;0.0459418931008004!GO:0006096;glycolysis;0.0462346976263313!GO:0009615;response to virus;0.0473192792133175!GO:0005777;peroxisome;0.0473192792133175!GO:0042579;microbody;0.0473192792133175!GO:0006400;tRNA modification;0.0473192792133175!GO:0043631;RNA polyadenylation;0.0489340736046761 | |||
|sample_id=10421 | |||
|sample_note=machine failed, remainder reloaded, low amount | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=blood | |||
|top_motifs=ZNF148:3.5397203404;NFY{A,B,C}:2.64734811131;NFIX:2.38289935844;GFI1:2.37818691604;MYB:1.9460177278;ELF1,2,4:1.66963536601;RORA:1.44016624204;ELK1,4_GABP{A,B1}:1.40995567805;NKX6-1,2:1.24432783427;E2F1..5:1.19699001413;VSX1,2:1.19536363453;FOXA2:1.10076952175;PITX1..3:0.99223944234;STAT1,3:0.989812229249;PBX1:0.980601338606;TEF:0.959172998181;YY1:0.935009568259;POU2F1..3:0.925357609646;ZNF143:0.907781762786;HOX{A6,A7,B6,B7}:0.859712396612;TLX2:0.82518599324;NR1H4:0.815048119673;CRX:0.757646319485;PAX3,7:0.731316729817;NRF1:0.686592091348;NFKB1_REL_RELA:0.658600821771;FOXP1:0.619431484555;RUNX1..3:0.606805760182;FOXP3:0.594043747832;AIRE:0.574949031327;PAX8:0.505135265243;POU3F1..4:0.496693557071;SPI1:0.482184745326;HOXA9_MEIS1:0.481852641675;FOX{F1,F2,J1}:0.478618033181;IRF1,2:0.446752667033;CREB1:0.407617043824;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.400057415034;ATF5_CREB3:0.388739740959;DMAP1_NCOR{1,2}_SMARC:0.379015404526;CUX2:0.366051182698;ETS1,2:0.355144196253;OCT4_SOX2{dimer}:0.315929410923;ONECUT1,2:0.308934077924;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.275896240122;HAND1,2:0.273768784928;HOX{A5,B5}:0.173000314345;ESRRA:0.1711133657;FOXN1:0.170491152728;BPTF:0.15856675862;EVI1:0.157538241233;SPIB:0.155626254542;BREu{core}:0.132392201325;ZEB1:0.129736092778;GATA6:0.127101179354;NKX2-2,8:0.113039341402;IRF7:0.101966028061;ATF4:0.0921992518689;FOX{I1,J2}:0.0865060268854;STAT5{A,B}:0.0672997537349;NANOG{mouse}:0.0621301220908;NKX3-2:0.055090493291;POU5F1:0.0491330948362;HOX{A4,D4}:0.0311099209664;GCM1,2:0.0110536425155;NKX3-1:0.00376601298124;CEBPA,B_DDIT3:-0.0332031138261;ZBTB16:-0.0499004925116;ADNP_IRX_SIX_ZHX:-0.0502813936737;NFE2L2:-0.074527789374;RFX2..5_RFXANK_RFXAP:-0.0750707602386;STAT2,4,6:-0.0891666660283;PAX4:-0.103449653941;GFI1B:-0.119359348467;FOSL2:-0.133021800696;NR5A1,2:-0.142104263022;AHR_ARNT_ARNT2:-0.186120358268;LEF1_TCF7_TCF7L1,2:-0.197278227627;PAX2:-0.20769895356;TGIF1:-0.20814798453;PAX6:-0.232516017508;SNAI1..3:-0.232716746274;HNF4A_NR2F1,2:-0.238470410207;SOX{8,9,10}:-0.240669096057;TFDP1:-0.254883314201;FOXO1,3,4:-0.255266094567;MYOD1:-0.259012594912;NFE2:-0.259478830966;HES1:-0.260861399026;FOS_FOS{B,L1}_JUN{B,D}:-0.26321723225;ALX1:-0.26854172952;NANOG:-0.287488958905;IKZF2:-0.295098402822;TOPORS:-0.299646680688;DBP:-0.312951335407;ARID5B:-0.33993166278;SOX17:-0.365322795225;HSF1,2:-0.369431026586;AR:-0.375736660848;POU1F1:-0.376059945739;RXRA_VDR{dimer}:-0.379815235162;HNF1A:-0.393386199102;NKX2-3_NKX2-5:-0.394514010199;JUN:-0.403533830561;SOX2:-0.414653599676;PRRX1,2:-0.419029743391;PPARG:-0.453002619248;LMO2:-0.462574617514;BACH2:-0.469492906728;CDX1,2,4:-0.491321012874;FOX{D1,D2}:-0.494148410355;NFIL3:-0.495782817438;MYFfamily:-0.518298977525;ATF2:-0.554154836308;MAFB:-0.563971946136;FOXM1:-0.593215936448;SMAD1..7,9:-0.604906803601;MEF2{A,B,C,D}:-0.609957954147;RBPJ:-0.612039610263;SP1:-0.615108720259;POU6F1:-0.630051685532;EP300:-0.634331650962;ESR1:-0.63922942569;ZNF384:-0.646850136854;MYBL2:-0.64878739251;TP53:-0.675889873315;NR3C1:-0.686380178291;NKX2-1,4:-0.700432427887;HLF:-0.743467473757;ATF6:-0.753187489533;ZNF423:-0.761610660515;SREBF1,2:-0.767772738236;UFEwm:-0.78428489523;NFE2L1:-0.793726877749;MTF1:-0.826789590213;ZNF238:-0.82786528817;SOX5:-0.854501444607;SRF:-0.85489133221;ZIC1..3:-0.86233152019;PAX5:-0.871333882437;CDC5L:-0.880817669042;RREB1:-0.902556758349;EN1,2:-0.907579121486;TBP:-0.933438580507;XCPE1{core}:-0.941009927813;FOXD3:-0.943922893076;LHX3,4:-0.951045005118;PAX1,9:-0.953003645221;ZBTB6:-0.963969665077;SPZ1:-0.966938358703;RFX1:-0.983329199849;GZF1:-0.991168256102;IKZF1:-1.01685336899;HMGA1,2:-1.02129570479;GTF2A1,2:-1.05636890285;bHLH_family:-1.08971688112;HBP1_HMGB_SSRP1_UBTF:-1.0941957101;PRDM1:-1.12288941814;TBX4,5:-1.13192328686;TFAP4:-1.14750501147;TAL1_TCF{3,4,12}:-1.15414266526;MED-1{core}:-1.17976975314;REST:-1.23447497255;KLF4:-1.25816396065;NFATC1..3:-1.25899620202;FOXQ1:-1.26598261118;TFCP2:-1.29023089;GTF2I:-1.30956730137;TLX1..3_NFIC{dimer}:-1.33167099716;T:-1.35213682117;ZFP161:-1.35827147539;TEAD1:-1.36031856806;GLI1..3:-1.37212758952;MAZ:-1.37995076141;NHLH1,2:-1.39066842827;HMX1:-1.39116034155;PDX1:-1.40910280532;ALX4:-1.41109675129;TFAP2{A,C}:-1.41140699775;MZF1:-1.46444794833;MTE{core}:-1.4740695439;XBP1:-1.50155921889;PATZ1:-1.53891935197;RXR{A,B,G}:-1.54717800834;HIC1:-1.56783060609;TFAP2B:-1.58505288152;FOXL1:-1.59383890221;EBF1:-1.6727365016;GATA4:-1.68687001445;NR6A1:-1.88529946848;EGR1..3:-2.03027478141;HIF1A:-2.22979992131 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10421-106C7;search_select_hide=table117:FF:10421-106C7 | |||
}} | }} |
Latest revision as of 14:00, 3 June 2020
Name: | adult T-cell leukemia cell line:ATN-1 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs10738 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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RNA-Seq Accession numbers | ||||||||||||||||||||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs10738
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs10738
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.0189 |
10 | 10 | 0.0206 |
100 | 100 | 0.52 |
101 | 101 | 0.0431 |
102 | 102 | 0.35 |
103 | 103 | 0.33 |
104 | 104 | 0.609 |
105 | 105 | 0.349 |
106 | 106 | 0.677 |
107 | 107 | 0.584 |
108 | 108 | 0.749 |
109 | 109 | 0.00216 |
11 | 11 | 0.0158 |
110 | 110 | 0.108 |
111 | 111 | 0.454 |
112 | 112 | 0.248 |
113 | 113 | 0.768 |
114 | 114 | 0.598 |
115 | 115 | 0.237 |
116 | 116 | 0.95 |
117 | 117 | 0.0095 |
118 | 118 | 0.873 |
119 | 119 | 0.332 |
12 | 12 | 0.815 |
120 | 120 | 0.422 |
121 | 121 | 0.361 |
122 | 122 | 0.43 |
123 | 123 | 0.0474 |
124 | 124 | 0.0118 |
125 | 125 | 0.405 |
126 | 126 | 0.235 |
127 | 127 | 0.464 |
128 | 128 | 0.504 |
129 | 129 | 0.577 |
13 | 13 | 0.0574 |
130 | 130 | 0.258 |
131 | 131 | 0.491 |
132 | 132 | 0.3 |
133 | 133 | 0.275 |
134 | 134 | 0.721 |
135 | 135 | 0.96 |
136 | 136 | 0.178 |
137 | 137 | 0.784 |
138 | 138 | 0.888 |
139 | 139 | 0.413 |
14 | 14 | 0.653 |
140 | 140 | 0.233 |
141 | 141 | 0.711 |
142 | 142 | 0.739 |
143 | 143 | 0.039 |
144 | 144 | 0.854 |
145 | 145 | 0.425 |
146 | 146 | 0.283 |
147 | 147 | 0.156 |
148 | 148 | 0.271 |
149 | 149 | 0.592 |
15 | 15 | 0.106 |
150 | 150 | 0.31 |
151 | 151 | 0.832 |
152 | 152 | 0.223 |
153 | 153 | 0.436 |
154 | 154 | 0.888 |
155 | 155 | 0.205 |
156 | 156 | 0.446 |
157 | 157 | 0.935 |
158 | 158 | 0.299 |
159 | 159 | 0.583 |
16 | 16 | 0.862 |
160 | 160 | 0.747 |
161 | 161 | 0.401 |
162 | 162 | 0.715 |
163 | 163 | 0.901 |
164 | 164 | 0.0391 |
165 | 165 | 0.786 |
166 | 166 | 0.211 |
167 | 167 | 0.188 |
168 | 168 | 0.765 |
169 | 169 | 0.281 |
17 | 17 | 0.537 |
18 | 18 | 0.543 |
19 | 19 | 0.891 |
2 | 2 | 0.629 |
20 | 20 | 0.622 |
21 | 21 | 0.555 |
22 | 22 | 0.911 |
23 | 23 | 0.545 |
24 | 24 | 0.315 |
25 | 25 | 0.205 |
26 | 26 | 0.0392 |
27 | 27 | 0.64 |
28 | 28 | 0.317 |
29 | 29 | 0.0476 |
3 | 3 | 0.0822 |
30 | 30 | 0.193 |
31 | 31 | 0.736 |
32 | 32 | 0.432 |
33 | 33 | 0.351 |
34 | 34 | 0.515 |
35 | 35 | 0.464 |
36 | 36 | 0.0236 |
37 | 37 | 0.29 |
38 | 38 | 0.454 |
39 | 39 | 0.909 |
4 | 4 | 0.0128 |
40 | 40 | 0.0514 |
41 | 41 | 0.784 |
42 | 42 | 0.0221 |
43 | 43 | 0.202 |
44 | 44 | 0.561 |
45 | 45 | 0.982 |
46 | 46 | 0.199 |
47 | 47 | 0.0132 |
48 | 48 | 0.062 |
49 | 49 | 0.0141 |
5 | 5 | 0.506 |
50 | 50 | 0.609 |
51 | 51 | 0.784 |
52 | 52 | 0.0585 |
53 | 53 | 0.154 |
54 | 54 | 0.904 |
55 | 55 | 0.751 |
56 | 56 | 0.394 |
57 | 57 | 0.343 |
58 | 58 | 0.164 |
59 | 59 | 0.864 |
6 | 6 | 0.753 |
60 | 60 | 0.987 |
61 | 61 | 0.21 |
62 | 62 | 0.162 |
63 | 63 | 0.744 |
64 | 64 | 0.197 |
65 | 65 | 0.672 |
66 | 66 | 1.20976e-9 |
67 | 67 | 0.46 |
68 | 68 | 0.415 |
69 | 69 | 0.718 |
7 | 7 | 0.0941 |
70 | 70 | 0.617 |
71 | 71 | 0.0364 |
72 | 72 | 0.763 |
73 | 73 | 0.735 |
74 | 74 | 0.761 |
75 | 75 | 0.0219 |
76 | 76 | 0.764 |
77 | 77 | 0.903 |
78 | 78 | 0.276 |
79 | 79 | 0.34 |
8 | 8 | 0.519 |
80 | 80 | 0.661 |
81 | 81 | 0.764 |
82 | 82 | 0.849 |
83 | 83 | 0.00519 |
84 | 84 | 0.666 |
85 | 85 | 0.847 |
86 | 86 | 0.0957 |
87 | 87 | 0.04 |
88 | 88 | 0.82 |
89 | 89 | 0.233 |
9 | 9 | 0.992 |
90 | 90 | 0.129 |
91 | 91 | 0.104 |
92 | 92 | 0.96 |
93 | 93 | 0.812 |
94 | 94 | 0.193 |
95 | 95 | 0.0102 |
96 | 96 | 0.191 |
97 | 97 | 0.263 |
98 | 98 | 0.674 |
99 | 99 | 0.638 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs10738
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0104049 adult T-cell lymphoma cell line sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0002371 (somatic cell)
0000542 (lymphocyte)
0000219 (motile cell)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0002242 (nucleate cell)
0000255 (eukaryotic cell)
0000084 (T cell)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
2531 (hematologic cancer)
0060058 (lymphoma)
14566 (disease of cellular proliferation)
0060083 (immune system cancer)
1240 (leukemia)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100737 (leukemia cell line sample)
0101035 (hematopoietic cell line sample)
0100104 (lymphoma cell line sample)
0103212 (T-lymphoma cell line sample)
0104049 (adult T-cell lymphoma cell line sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)
CL:0000051 (common lymphoid progenitor)