FF:11560-120D3: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005411 | ||
| | |accession_numbers=CAGE;DRX008286;DRR009158;DRZ000583;DRZ001968;DRZ011933;DRZ013318 | ||
| | |ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0002097,UBERON:0002199,UBERON:0002384,UBERON:0000479,UBERON:0000062,UBERON:0000061,UBERON:0000465,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0003102,UBERON:0002416 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0002320,CL:0002371,CL:0000255,CL:0000057,CL:0002620 | |||
|ancestors_in_disease_facet=DOID:4,DOID:17,DOID:450,DOID:7,DOID:66,DOID:423,DOID:0080000,DOID:11722 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000057,FF:0000250,FF:0000001,FF:0000253 | |||
|comment= | |||
|created_by= | |||
|creation_date= | |||
| | |data_phase=2 | ||
| | |datafreeze_phase=2 | ||
|def= | |||
|expression_enrichment_score=chr1:197886461..197886558,+!p1@LHX9!2.50!312.35!LHX9;;chr15:57511609..57511651,+!p2@TCF12!1.81!105.01!TCF12;;chr7:19157248..19157268,-!p1@TWIST1!1.56!95.74!TWIST1;;chr4:174451370..174451387,-!p1@HAND2!1.54!33.90!HAND2;;chr2:239756739..239756755,+!p2@TWIST2!1.47!47.82!TWIST2;;chr9:132427972..132428056,+!p1@PRRX2!1.47!36.69!PRRX2;;chr9:132427883..132427951,+!p2@PRRX2!1.45!26.90!PRRX2;;chr10:119303078..119303169,+!p2@EMX2!1.45!26.90!EMX2;;chr2:239756671..239756732,+!p1@TWIST2!1.44!82.34!TWIST2;;chr1:170632285..170632309,+!p1@PRRX1!1.44!29.68!PRRX1;;chr12:54410664..54410684,+!p1@HOXC4,p1@HOXC5,p1@HOXC6!1.39!23.29!HOXC5;;chr4:174450089..174450153,-!p2@HAND2!1.37!22.47!HAND2;;chr11:46299199..46299233,+!p1@CREB3L1!1.36!110.47!CREB3L1;;chr1:170633348..170633399,+!p2@PRRX1!1.31!26.07!PRRX1;;chr19:13134772..13134822,+!p2@NFIX!1.27!26.07!NFIX;;chr5:2751762..2751784,-!p1@IRX2!1.20!14.74!IRX2;;chr5:72744594..72744609,-!p1@FOXD1!1.17!63.27!FOXD1;;chr8:93074803..93074845,-!p1@RUNX1T1!1.17!13.91!RUNX1T1;;chr15:83953397..83953425,-!p1@BNC1!1.11!13.60!BNC1;;chr21:36260773..36260804,-!p7@RUNX1!1.09!15.15!RUNX1;;chr16:86544113..86544145,+!p1@FOXF1!1.09!13.91!FOXF1;;chr1:197886665..197886732,+!p3@LHX9!1.05!10.31!LHX9;;chr10:28034739..28034756,-!p1@MKX!1.04!10.00!MKX;;chr1:170633262..170633285,+!p3@PRRX1!1.03!11.03!PRRX1;;chr20:51588873..51588953,+!p1@TSHZ2!1.02!12.47!TSHZ2;;chr20:55204351..55204377,+!p1@TFAP2C!1.02!12.06!TFAP2C;;chr5:72744445..72744466,-!p2@FOXD1!1.00!15.15!FOXD1;;chrY:21906594..21906622,-!p1@KDM5D!0.99!8.86!KDM5D;;chr2:176994408..176994492,+!p1@HOXD8!0.99!8.86!HOXD8;;chr1:197886421..197886432,+!p2@LHX9!0.98!8.66!LHX9;;chrY:2803415..2803468,+!p1@ZFY!0.98!8.55!ZFY;;chr5:2751785..2751808,-!p2@IRX2!0.98!8.45!IRX2;;chr8:93074848..93074871,-!p3@RUNX1T1!0.98!8.45!RUNX1T1;;chr3:157823517..157823562,-!p1@SHOX2!0.95!8.55!SHOX2;;chr10:119302232..119302265,+!p1@EMX2!0.95!7.94!EMX2;;chr7:44143925..44143970,+!p1@AEBP1!0.94!176.84!AEBP1;;chr7:27224842..27224872,-!p1@HOXA11!0.94!7.73!HOXA11;;chr1:170632959..170632987,+!p4@PRRX1!0.93!8.24!PRRX1;;chr6:134210243..134210257,+!p1@TCF21!0.93!7.42!TCF21;;chr10:63809106..63809127,+!p1@ARID5B!0.92!103.67!ARID5B;;chr11:46299539..46299620,+!p2@CREB3L1!0.92!12.78!CREB3L1;;chr7:27205136..27205164,-!p1@HOXA9!0.91!7.21!HOXA9;;chr15:37392616..37392638,-!p2@MEIS2!0.90!22.47!MEIS2;;chr14:24837368..24837401,+!p1@NFATC4!0.90!17.11!NFATC4;;chr2:102091566..102091581,-!p1@RFX8!0.90!6.90!RFX8;;chr2:176969228..176969260,+!p1@HOXD11!0.90!6.90!HOXD11;;chr12:53614115..53614154,-!p1@RARG!0.89!38.03!RARG;;chr18:22932080..22932170,-!p1@ZNF521!0.89!30.19!ZNF521;;chr15:37390850..37390909,-!p3@MEIS2!0.89!13.60!MEIS2;;chr10:31610110..31610159,+!p2@ZEB1!0.89!6.80!ZEB1;;chr17:46682321..46682362,-!p1@HOXB6!0.89!6.70!HOXB6;;chr5:321810..321877,+!p1@AHRR!0.88!21.64!AHRR;;chr7:27205106..27205134,-!p2@HOXA9!0.88!6.60!HOXA9;;chr2:19558373..19558392,-!p1@OSR1!0.87!18.24!OSR1;;chr15:57511589..57511608,+!p4@TCF12!0.87!6.49!TCF12;;chr12:54402745..54402788,+!p1@HOXC8!0.87!6.49!HOXC8;;chr7:27192185..27192209,-!p1@HOXA3!0.86!6.29!HOXA3;;chr11:65687362..65687436,+!p3@DRAP1!0.85!29.58!DRAP1;;chr12:54410639..54410659,+!p2@HOXC4,p2@HOXC5,p2@HOXC6!0.85!6.08!HOXC5;;chr3:147111231..147111281,+!p3@ZIC1!0.85!6.08!ZIC1;;chr7:27224795..27224840,-!p2@HOXA11!0.85!6.08!HOXA11;;chr19:13135386..13135435,+!p4@NFIX!0.84!5.98!NFIX;;chr11:65686732..65686756,+!p2@DRAP1!0.83!26.07!DRAP1;;chr3:141121847..141121868,+!p5@ZBTB38!0.83!9.07!ZBTB38;;chr3:147111198..147111225,+!p4@ZIC1!0.83!5.77!ZIC1;;chr7:42276787..42276815,-!p1@GLI3!0.82!15.87!GLI3;;chr1:170632250..170632277,+!p7@PRRX1!0.82!5.67!PRRX1;;chr8:67525443..67525459,-!p2@MYBL1!0.81!8.45!MYBL1;;chr16:31076332..31076388,-!p3@ZNF668!0.80!5.36!ZNF668;;chr3:128206762..128206781,-!p2@GATA2!0.79!34.83!GATA2;;chr10:63809013..63809041,+!p3@ARID5B!0.79!31.02!ARID5B;;chr18:53068911..53068935,-!p4@TCF4!0.79!5.98!TCF4;;chr3:21792585..21792625,-!p2@ZNF385D!0.79!5.87!ZNF385D;;chr2:96012397..96012417,+!p3@KCNIP3!0.79!5.15!KCNIP3;;chr3:138665937..138665968,-!p1@FOXL2!0.79!5.15!FOXL2;;chr15:37392724..37392757,-!p1@MEIS2!0.78!24.84!MEIS2;;chr1:158979872..158979898,+!p3@IFI16!0.78!16.80!IFI16;;chr7:44143978..44143989,+!p2@AEBP1!0.78!9.79!AEBP1;;chr7:14029283..14029311,-!p1@ETV1!0.77!28.55!ETV1;;chr11:65686802..65686818,+!p6@DRAP1!0.77!8.97!DRAP1;;chr22:19748231..19748317,+!p1@TBX1!0.77!4.95!TBX1;;chr5:3595977..3595999,+!p1@IRX1!0.77!4.84!IRX1;;chr1:158979792..158979814,+!p2@IFI16!0.76!49.77!IFI16;;chr1:170633058..170633084,+!p5@PRRX1!0.75!4.64!PRRX1;;chr19:13135582..13135600,+!p3@NFIX!0.75!4.64!NFIX;;chr8:49833948..49833973,-!p2@SNAI2!0.74!31.43!SNAI2;;chr15:42749722..42749739,-!p2@ZFP106!0.74!8.45!ZFP106;;chr6:100912785..100912822,-!p1@SIM1!0.74!4.53!SIM1;;chr10:31608127..31608156,+!p1@ZEB1!0.73!90.17!ZEB1;;chr4:4861385..4861398,+!p1@MSX1!0.73!14.12!MSX1;;chr11:65687222..65687240,+!p7@DRAP1!0.73!5.77!DRAP1;;chr7:44143997..44144008,+!p3@AEBP1!0.73!5.77!AEBP1;;chr5:142780189..14278022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;;chrX:101975643..101975683,+!p1@BHLHB9!0.17!2.16!BHLHB9;;chr10:43932296..43932360,+!p1@ZNF487P!0.17!1.96!ZNF487P;;chr3:114343826..114343869,-!p4@ZBTB20!0.17!1.85!ZBTB20;;chr3:141820622..141820635,-!p5@TFDP2!0.17!1.55!TFDP2;;chr4:56413067..56413086,-!p4@CLOCK!0.17!1.55!CLOCK;;chr6:85474299..85474324,-!p1@TBX18!0.17!1.55!TBX18;;chr1:151043070..151043110,+!p3@GABPB2!0.17!1.34!GABPB2;;chr3:71632743..71632756,-!p16@FOXP1!0.17!1.24!FOXP1;;chr12:56401175..56401225,+!p3@IKZF4!0.17!1.13!IKZF4;;chr16:4365715..4365746,+!p@chr16:4365715..4365746,+!0.17!0.93!GLIS2;;chr2:46602901..46602926,+!p7@EPAS1!0.17!0.93!EPAS1;;chr4:1873216..1873238,+!p5@WHSC1!0.17!0.93!WHSC1;;chr19:57078386..57078407,+!p3@ZNF470!0.17!0.93!ZNF470;;chr15:67358269..67358272,+!p15@SMAD3!0.17!0.82!SMAD3;;chr10:63851669..63851682,+!p10@ARID5B!0.17!0.62!ARID5B;;chr2:121493717..121493755,+!p3@GLI2!0.17!0.62!GLI2;;chr3:71179785..71179810,-!p23@FOXP1!0.17!0.62!FOXP1;;chr5:138629417..138629446,+!p1@MATR3!0.16!120.98!MATR3;;chr2:178129414..178129517,-!p1@NFE2L2!0.16!51.22!NFE2L2;;chr11:128392085..128392232,-!p1@ETS1!0.16!43.69!ETS1;;chr14:21945335..21945419,+!p1@TOX4!0.16!33.49!TOX4;;chr7:106809432..106809455,+!p1@HBP1!0.16!24.94!HBP1;;chr14:74353530..74353571,+!p1@ZNF410!0.16!23.81!ZNF410;;chr6:35464817..35464894,-!p1@TEAD3!0.16!19.37!TEAD3;;chr18:32870148..32870223,-!p1@ZSCAN30!0.16!8.55!ZSCAN30;;chr12:27485785..27485816,+!p1@ARNTL2!0.16!8.35!ARNTL2;;chr15:67357924..67357952,+!p2@SMAD3!0.16!8.04!SMAD3;;chr1:38325256..38325280,-!p1@MTF1!0.16!7.32!MTF1;;chr4:146859927..146860055,-!p1@ZNF827!0.16!7.11!ZNF827;;chr2:85360499..85360598,+!p1@TCF7L1!0.16!6.60!TCF7L1;;chr3:44519131..44519186,-!p1@ZNF445!0.16!6.60!ZNF445;;chr14:74226747..74226779,-!p3@C14orf43!0.16!6.60!C14orf43;;chr4:140005341..140005411,-!p3@ELF2!0.16!6.29!ELF2;;chr19:53836985..53837024,+!p1@ZNF845!0.16!5.67!ZNF845;;chr3:44596679..44596726,+!p1@ZNF167!0.16!4.95!ZNF167;;chr17:56065729..56065781,-!p2@VEZF1!0.16!4.84!VEZF1;;chr1:8483878..8483907,-!p4@RERE!0.16!4.33!RERE;;chr19:44439387..44439419,-!p2@ZNF45!0.16!4.12!ZNF45;;chr19:53758094..53758147,-!p1@ZNF677!0.16!4.12!ZNF677;;chr3:63897742..63897797,+!p2@ATXN7!0.16!3.61!ATXN7;;chr6:126102292..126102329,+!p3@NCOA7!0.16!3.50!NCOA7;;chr3:169490562..169490605,+!p2@MYNN!0.16!3.40!MYNN;;chr16:29819446..29819471,+!p9@MAZ!0.16!3.09!MAZ;;chr5:34929947..34930005,+!p3@DNAJC21!0.16!2.99!DNAJC21;;chr3:52001426..52001447,-!p3@PCBP4!0.16!2.89!PCBP4;;chr4:1873155..1873185,+!p3@WHSC1!0.16!2.89!WHSC1;;chr2:148778973..148779035,+!p3@MBD5!0.16!2.58!MBD5;;chr1:23694697..23694756,-!p3@ZNF436!0.16!2.16!ZNF436;;chr4:144435112..144435176,+!p3@SMARCA5!0.16!1.85!SMARCA5;;chr11:9482521..9482533,+!p2@ZNF143!0.16!1.65!ZNF143;;chr3:40566488..40566502,+!p3@ZNF621!0.16!1.55!ZNF621;;chr8:182368..182402,+!p2@ZNF596!0.16!1.55!ZNF596;;chr3:71630690..71630750,-!p11@FOXP1!0.16!1.34!FOXP1;;chr6:42419316..42419340,-!p4@TRERF1!0.16!1.13!TRERF1;;chr17:38792325..38792330,-!p3@SMARCE1!0.16!1.03!SMARCE1;;chrX:66763856..66763896,+!p1@AR!0.16!1.03!AR;;chrX:129402754..129402766,-!p3@ZNF280C!0.16!0.93!ZNF280C;;chr11:6947647..6947698,+!p2@ZNF215!0.16!0.93!ZNF215;;chr12:66218443..66218461,+!p8@HMGA2!0.16!0.82!HMGA2;;chr22:29196030..29196075,-!p5@XBP1!0.16!0.82!XBP1;;chr2:231077626..231077651,-!p6@SP110!0.16!0.82!SP110;;chr19:50431973..50431998,+!p5@ATF5!0.16!0.82!ATF5;;chr21:36231861..36231877,-!p12@RUNX1!0.16!0.82!RUNX1;;chr5:124082279..124082319,-!p3@ZNF608!0.16!0.72!ZNF608;; | |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000057;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0002620;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002097;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002416 | |||
|ffid_belonging_in_development=CL:0000134 | |||
| | |||
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|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 41: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|top_motifs= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520skin%2520dystrophia%2520myotonica%252c%2520donor3.CNhs11913.11560-120D3.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520skin%2520dystrophia%2520myotonica%252c%2520donor3.CNhs11913.11560-120D3.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520skin%2520dystrophia%2520myotonica%252c%2520donor3.CNhs11913.11560-120D3.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520skin%2520dystrophia%2520myotonica%252c%2520donor3.CNhs11913.11560-120D3.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520skin%2520dystrophia%2520myotonica%252c%2520donor3.CNhs11913.11560-120D3.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11560-120D3 | |||
|is_a=EFO:0002091;;FF:0000253 | |||
|is_obsolete= | |||
|library_id=CNhs11913 | |||
|library_id_phase_based=2:CNhs11913 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11560 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11560 | |||
|name=Fibroblast - skin dystrophia myotonica, donor3 | |||
|namespace=FANTOM5 | |||
|part_of= | |||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs11913,LSID842,release014,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0.0212980973874494,0,0,0,0,-0.0104187116675691,0,-0.195976993270332,-0.261105463189493,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.153323010348428,0,0,0,0,0,-0.0979578962680575,0,0,-0.132956589778862,0,0,0,0,0,0,0,0,0,0,0.11699192718931,0,-0.146773469171265,0,0,0,0,0,0,0,0,-0.0242150211128343,0,0,0,0,0,0,0,-0.0969923612426051,0,0,0.019648299976213,0,0,0,0,0,0,0,0,0.0425961947748989,0,0,0,0,0,0,0,0,0,0.0406925694615912,0,0,0,0,0,0,0.058495963594655,0,0,-0.0437156328759035,-0.0053208066793887,0,0.261124880180198,0.0406925694615912,0.180487917264505,-0.016650212314524,-0.117179103413446,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.246687036389703,0,0,0,-0.174304964963451,-0.516393100219322,0,0,0,0,0,0 | |||
|repeat_enrich_byname=0,0,0,0,-0.016650212314524,0,0.180487917264505,0,0,0.0813851389231825,0,0.11699192718931,0,0.261124880180198,0,0,0.0819296129620202,0.0212980973874494,0.103683336097993,-0.143515142523472,0,0,0.0826652850161543,0,0.0813851389231825,0,0,0.0425961947748989,0.0425961947748989,0,0,0,0.535283122888761,0,-0.0504125515893149,0,0,0.114943239569155,0,0,-0.0443473507182097,0,0.0455577103741077,0.140718845581172,0,0,0,0,0.0416343699681566,0,-0.0394943448705582,0.0342717588658926,0.06337666170761,0.1454648155984,-0.055712496781182,0,0,0,0.0783851267662006,0.139887926903821,0,0,0.342718888220229,-0.106399959351251,0,0,1.3549734865913,0,0.127481196007643,0.068656603624182,0,0,0,0,0,0,0,0,0,0,0,0,0,0.238804859816934,-0.0658637164987713,0,0,0.0425961947748989,0,-0.0670631143858693,0,0,-0.373286155956567,-0.0525311980580465,-0.0231531701512942,-0.410025356427671,0,-0.302389727009913,-0.0218829882813033,-0.0682493257160749,-0.0217582671173144,0.240474578516104,0.375791242986537,0.0243549181755007,0.0612679479779292,0.216697432316501,0.0140372550985705,-0.220317214879041,-0.0226346337640242,0.123487693745286,-0.15955621439997,0,0,0,0.084895556977408,0,0,0.163463031534684,-0.00262797915217755,0.142834323097928,-0.0190039778454157,-0.0285833987055619,-0.0565412147676794,-0.0182344310692211,0.243184951614143,0,0.2296093634465,0,0,-0.0258409462183493,-0.0371628357728894,-0.0192413720359882,-0.330837923368262,0,-0.334078143392164,-0.0683442610773682,0,-0.035131937455403,-0.204087803429655,0,0,-0.107779346698274,0,0,0,0,0,-0.080954605874237,-0.068494258857028,-0.115863634366235,0,-0.0268343534738351,0.00594604230585088,-0.154791955447378,0,0.00609467081671144,0.00388942096142278,-0.148252364844306,-0.123734165620187,0,-0.0814935972588622,0.183886601146353,-0.00143019082007279,-0.0532378081336763,-0.0584468268118252,-0.0480611629454304,-0.16764326922556,-0.00770104699707352,0.256349772413108,-0.00821875211678813,1.08541172581841,0,0.218371878332955,-0.499010214357019,-0.110606296125904,-0.045213129846834,0,0.226285539079366,0,-0.0698249917078686,0,-0.326530581247561,-0.255445501662823,-0.396693179805787,-0.0325507409830399,0,-0.201064612242628,0.625817470662533,0,0.035224030294343,0.0189634351379844,0,0.255455141221919,-0.291873741956024,-0.170957858402998,0.271487401379538,0,0.221690159776748,0,0.0425961947748989,-0.0939481030856945,-0.0855767193455717,0,0.08118108365428,0.0343221516360324,-0.090046216976166,-0.0733748786600351,0,0.0425961947748989,0.246475933876026,0,0.180487917264505,-0.425440146553525,0.261124880180198,-0.0303396723624703,0.169729461267263,0,-0.108622809454255,0,0,0.031535340693365,0,0.138978413016092,0,0,-0.0488912080989603,0,0,0,0.11699192718931,-0.052771565652556,0,0,0,0,0,0,0,-0.122759717806252,-0.0698450804060312,0,0.0813851389231825,0,0,0,0,0,0.0470304424281687,0,0.485870506501754,1.16796119197291,0.042592276815899,-0.00602548848711033,0.0406925694615912,0,0,0,0.172153025333768,0.0578883180854738,0.0425961947748989,0.0180366119211853,0,0,0,0,-0.00475585086602889,0,0,0,0.0212980973874494,-0.057730457053664,-0.151474992814132,0,0,0,-0.234358206826891,0,0,0.0425961947748989,0.050416359368278,0.0384014090743765,0,0,0.265945299533481,0,-0.0263796955425879,-0.0815818795468414,0,0.16982818657735,0.365075684347955,-0.0184856801751125,0,0.0425961947748989,-0.218750937014989,0,0.0448538665534032,0.236478317175756,0,0,0,0,0,0,0,0,0.0813851389231825,0.154842484858306,0.10453155332927,0,0,0,0,0,0,0,0,0,0,0.0305640561898539,0.0882638606059948,0,0,0,0,0,0,0,0.273909849018201,-0.209899035193615,0.0212980973874494,0,0.0212980973874494,0,0,0.0425961947748989,0,0,-0.0317943966160071,0,0,0,0,0,-0.0969923612426051,0,0,0,0.0425961947748989,-0.522210926378985,0,0,-0.195976993270332,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0063271588461378,-0.481646262767367,0,0,0,0,0,0,0,-0.157841371016781,0,0,0,0,0.066603543555528,0,0,0,0.0756915324753488,0,-0.0104187116675691,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0212980973874494,0,0,0,0.570013516664353,0.0964334355860866,0,0,0,0,0.142909679152186,0,0,0,0,0,0,0.0436092351808815,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.00583452565650285,0,0,0,0,0.11699192718931,0,0,-0.0979578962680575,0,0.0212980973874494,-0.0513402403389349,0,0,0,0,0,0,0.329598720438233,0.348221450993906,-0.00710104646019665,0,0,0,0.20269933962711,0,0,-0.00114824894418275,0,0.339044837137657,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.153323010348428,0,0,0,0,0,0,0,0,0,0,0,0,0.0406925694615912,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0813851389231825,0.0212980973874494,0,0,0,0,0,0,0.0066812061861747,0.0425961947748989,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0800184682686384,0,0,0,-0.0631869112382267,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0425961947748989,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.255529548531578,0,0,0,0,0,0,0,0,0.11699192718931,0,0,0,0,-0.00562588046415528,0,-0.0843766322300271,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0813851389231825,-0.46911890359253,0,0,0,0,-0.0476371106609188,0,0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| |||
|rna_box=120 | |||
|rna_catalog_number=custom | |||
|rna_concentration=1.185 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-TRIzol-ethanol-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=2.06 | |||
|rna_od260/280=2.1 | |||
|rna_position=D3 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=120D3 | |||
|rna_weight_ug=160.002 | |||
|sample_age=18 year old adult | |||
|sample_category=primary cells | |||
|sample_cell_catalog=N/A | |||
|sample_cell_line= | |||
|sample_cell_lot=GM03132 | |||
|sample_cell_type=fibroblast | |||
|sample_collaboration=Splicing (contact: Al Forrest) | |||
|sample_company=Coriell | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=DYSTROPHIA MYOTONICA 1; DM1 | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=C | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;8.27742528533473e-237!GO:0043226;organelle;2.59402453792287e-191!GO:0043229;intracellular organelle;5.07754623869263e-191!GO:0043231;intracellular membrane-bound organelle;3.47725411085415e-188!GO:0043227;membrane-bound organelle;7.37632895840374e-188!GO:0005737;cytoplasm;3.29775779608814e-174!GO:0044422;organelle part;1.37172992382053e-129!GO:0044446;intracellular organelle part;3.74204736496267e-128!GO:0044444;cytoplasmic part;4.99268352369144e-123!GO:0032991;macromolecular complex;2.13219258966316e-91!GO:0044238;primary metabolic process;5.99637678811241e-86!GO:0043170;macromolecule metabolic process;3.06918003051603e-85!GO:0044237;cellular metabolic process;5.56254981585366e-85!GO:0030529;ribonucleoprotein complex;1.40784716492139e-80!GO:0005634;nucleus;1.81273500495737e-80!GO:0005515;protein binding;7.65926632433815e-78!GO:0043233;organelle lumen;1.42932239067829e-68!GO:0031974;membrane-enclosed lumen;1.42932239067829e-68!GO:0003723;RNA binding;1.42932239067829e-68!GO:0044428;nuclear part;2.92473123719059e-67!GO:0005739;mitochondrion;2.7138768787786e-53!GO:0016043;cellular component organization and biogenesis;1.8181099602846e-50!GO:0019538;protein metabolic process;4.82307200986136e-47!GO:0043283;biopolymer metabolic process;6.02552822438829e-47!GO:0005840;ribosome;8.74123590888495e-47!GO:0006396;RNA processing;3.76063169033103e-46!GO:0010467;gene expression;4.85890142790227e-46!GO:0033036;macromolecule localization;1.44447845481573e-45!GO:0043234;protein complex;1.95199544550609e-45!GO:0006412;translation;2.30608443910185e-45!GO:0015031;protein transport;7.73822683098723e-45!GO:0031090;organelle membrane;4.11641721381443e-43!GO:0031981;nuclear lumen;4.61009303073167e-43!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;8.25293503850814e-43!GO:0008104;protein localization;8.37457837030542e-42!GO:0045184;establishment of protein localization;1.50542210562112e-41!GO:0044260;cellular macromolecule metabolic process;3.41098523962141e-41!GO:0003735;structural constituent of ribosome;4.10977706685905e-41!GO:0044267;cellular protein metabolic process;1.56987246287688e-40!GO:0016071;mRNA metabolic process;4.74036407318676e-38!GO:0005829;cytosol;8.39036152091347e-37!GO:0044429;mitochondrial part;4.98748916953659e-36!GO:0033279;ribosomal subunit;1.3499305983164e-35!GO:0046907;intracellular transport;2.82788364949758e-35!GO:0008380;RNA splicing;3.47232071613956e-35!GO:0009059;macromolecule biosynthetic process;1.25820755227729e-34!GO:0006397;mRNA processing;4.97512972227474e-33!GO:0031967;organelle envelope;2.12661379801783e-32!GO:0009058;biosynthetic process;2.47121277620485e-32!GO:0031975;envelope;4.78634947358251e-32!GO:0043228;non-membrane-bound organelle;7.45989569679441e-32!GO:0043232;intracellular non-membrane-bound organelle;7.45989569679441e-32!GO:0044249;cellular biosynthetic process;1.70062078279692e-31!GO:0065003;macromolecular complex assembly;1.82571679553737e-31!GO:0006996;organelle organization and biogenesis;1.94330645077534e-31!GO:0006886;intracellular protein transport;4.56939395610547e-30!GO:0022613;ribonucleoprotein complex biogenesis and assembly;4.95749386327983e-29!GO:0003676;nucleic acid binding;1.6091040033296e-28!GO:0022607;cellular component assembly;2.60641879094307e-28!GO:0005654;nucleoplasm;2.10267988444271e-27!GO:0005830;cytosolic ribosome (sensu Eukaryota);3.16382325346087e-27!GO:0006259;DNA metabolic process;1.31908366958532e-24!GO:0005681;spliceosome;1.89355306674504e-24!GO:0005740;mitochondrial envelope;5.70567377024234e-23!GO:0051649;establishment of cellular localization;2.67364158426846e-22!GO:0051641;cellular localization;3.59706884310533e-22!GO:0016070;RNA metabolic process;4.25809583841376e-22!GO:0044451;nucleoplasm part;7.09500770340069e-22!GO:0031966;mitochondrial membrane;1.00136416338058e-21!GO:0044445;cytosolic part;2.31904666698664e-21!GO:0019866;organelle inner membrane;3.45681908066331e-21!GO:0000166;nucleotide binding;2.76981972237851e-20!GO:0006457;protein folding;2.7960424850666e-20!GO:0006119;oxidative phosphorylation;5.15560630071677e-20!GO:0005743;mitochondrial inner membrane;8.24434248224504e-20!GO:0007049;cell cycle;2.32431557638539e-19!GO:0016462;pyrophosphatase activity;2.9572678187655e-19!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;3.28748878254133e-19!GO:0016817;hydrolase activity, acting on acid anhydrides;5.1902238314149e-19!GO:0017111;nucleoside-triphosphatase activity;1.33355932967012e-18!GO:0022618;protein-RNA complex assembly;1.41855372034828e-18!GO:0005783;endoplasmic reticulum;1.47587354745334e-18!GO:0048770;pigment granule;1.85026102325726e-18!GO:0042470;melanosome;1.85026102325726e-18!GO:0015935;small ribosomal subunit;2.36296124104633e-18!GO:0015934;large ribosomal subunit;3.27397630081309e-18!GO:0012505;endomembrane system;9.02394048650156e-18!GO:0008134;transcription factor binding;1.56083882007919e-17!GO:0044455;mitochondrial membrane part;2.88276395370532e-17!GO:0016874;ligase activity;1.14436661663946e-16!GO:0006512;ubiquitin cycle;3.804964387277e-16!GO:0005730;nucleolus;4.94113937134352e-16!GO:0008135;translation factor activity, nucleic acid binding;6.02170768074486e-16!GO:0051603;proteolysis involved in cellular protein catabolic process;7.99389326243985e-16!GO:0048193;Golgi vesicle transport;8.06620562970663e-16!GO:0005794;Golgi apparatus;1.13726739178027e-15!GO:0031980;mitochondrial lumen;1.21355367962384e-15!GO:0005759;mitochondrial matrix;1.21355367962384e-15!GO:0019941;modification-dependent protein catabolic process;1.70954068052046e-15!GO:0043632;modification-dependent macromolecule catabolic process;1.70954068052046e-15!GO:0006511;ubiquitin-dependent protein catabolic process;2.38171099431817e-15!GO:0000502;proteasome complex (sensu Eukaryota);2.38541562566364e-15!GO:0044257;cellular protein catabolic process;2.55131596621352e-15!GO:0044265;cellular macromolecule catabolic process;2.72585523007519e-15!GO:0043285;biopolymer catabolic process;4.3078227080855e-15!GO:0022402;cell cycle process;1.31501206180167e-14!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;1.50239335565444e-14!GO:0005746;mitochondrial respiratory chain;1.62157414027234e-14!GO:0044432;endoplasmic reticulum part;1.92917215665599e-14!GO:0006605;protein targeting;2.12482296184818e-14!GO:0006974;response to DNA damage stimulus;2.16463380927602e-14!GO:0051082;unfolded protein binding;4.30275061308248e-14!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);5.5299710991962e-14!GO:0030163;protein catabolic process;7.02066067397019e-14!GO:0009057;macromolecule catabolic process;8.77011637263902e-14!GO:0016192;vesicle-mediated transport;9.94581146114016e-14!GO:0000278;mitotic cell cycle;1.01589871687548e-13!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.60451032071258e-13!GO:0032553;ribonucleotide binding;2.02749984961229e-13!GO:0032555;purine ribonucleotide binding;2.02749984961229e-13!GO:0017076;purine nucleotide binding;2.14285916865229e-13!GO:0000398;nuclear mRNA splicing, via spliceosome;2.31134909484448e-13!GO:0000375;RNA splicing, via transesterification reactions;2.31134909484448e-13!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;2.31134909484448e-13!GO:0050136;NADH dehydrogenase (quinone) activity;3.35602937723298e-13!GO:0003954;NADH dehydrogenase activity;3.35602937723298e-13!GO:0008137;NADH dehydrogenase (ubiquinone) activity;3.35602937723298e-13!GO:0005793;ER-Golgi intermediate compartment;1.41781235758211e-12!GO:0003743;translation initiation factor activity;1.50078259129244e-12!GO:0051186;cofactor metabolic process;2.00505737127737e-12!GO:0005761;mitochondrial ribosome;2.60610756285568e-12!GO:0000313;organellar ribosome;2.60610756285568e-12!GO:0003712;transcription cofactor activity;3.5669243701772e-12!GO:0006413;translational initiation;7.36438739380333e-12!GO:0050794;regulation of cellular process;7.49629577296579e-12!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;8.22929449322664e-12!GO:0042775;organelle ATP synthesis coupled electron transport;1.1085733336744e-11!GO:0042773;ATP synthesis coupled electron transport;1.1085733336744e-11!GO:0006281;DNA repair;1.17887691383477e-11!GO:0044248;cellular catabolic process;1.39215043468005e-11!GO:0030964;NADH dehydrogenase complex (quinone);1.52710401583413e-11!GO:0045271;respiratory chain complex I;1.52710401583413e-11!GO:0005747;mitochondrial respiratory chain complex I;1.52710401583413e-11!GO:0042254;ribosome biogenesis and assembly;2.66871901794465e-11!GO:0016604;nuclear body;3.2644143577858e-11!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;3.65592710613952e-11!GO:0005694;chromosome;5.28113990944924e-11!GO:0051276;chromosome organization and biogenesis;9.18048783076079e-11!GO:0043412;biopolymer modification;1.23898775389313e-10!GO:0005524;ATP binding;1.26801984380529e-10!GO:0009719;response to endogenous stimulus;1.79012877195567e-10!GO:0006446;regulation of translational initiation;2.66257690344223e-10!GO:0032559;adenyl ribonucleotide binding;2.98549628601033e-10!GO:0000087;M phase of mitotic cell cycle;3.03070797229229e-10!GO:0009055;electron carrier activity;3.59810334610726e-10!GO:0030554;adenyl nucleotide binding;4.04819381477004e-10!GO:0007067;mitosis;4.47153287859356e-10!GO:0005635;nuclear envelope;4.85650578745759e-10!GO:0042175;nuclear envelope-endoplasmic reticulum network;5.53562513421626e-10!GO:0008639;small protein conjugating enzyme activity;8.06878668397358e-10!GO:0006366;transcription from RNA polymerase II promoter;8.2565271575639e-10!GO:0006913;nucleocytoplasmic transport;8.75937784442195e-10!GO:0006325;establishment and/or maintenance of chromatin architecture;1.07462382606335e-09!GO:0022403;cell cycle phase;1.08366048858876e-09!GO:0051301;cell division;1.09323782680485e-09!GO:0006732;coenzyme metabolic process;1.13647182791475e-09!GO:0008565;protein transporter activity;1.22911311971097e-09!GO:0031965;nuclear membrane;1.2617944974674e-09!GO:0009259;ribonucleotide metabolic process;1.38519712302717e-09!GO:0004842;ubiquitin-protein ligase activity;1.46834471039206e-09!GO:0016607;nuclear speck;1.57880768582956e-09!GO:0005789;endoplasmic reticulum membrane;1.79627778708621e-09!GO:0051169;nuclear transport;1.80909382812249e-09!GO:0044427;chromosomal part;1.85256595997086e-09!GO:0019787;small conjugating protein ligase activity;2.11215430065523e-09!GO:0006461;protein complex assembly;2.12729021809001e-09!GO:0006464;protein modification process;2.48463583677767e-09!GO:0006323;DNA packaging;3.06383999051428e-09!GO:0042623;ATPase activity, coupled;3.16624393986566e-09!GO:0016887;ATPase activity;3.45144872907536e-09!GO:0044453;nuclear membrane part;3.53932815398909e-09!GO:0006163;purine nucleotide metabolic process;3.70233465465384e-09!GO:0006888;ER to Golgi vesicle-mediated transport;3.80676229928668e-09!GO:0004386;helicase activity;4.12140892665922e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;5.36047980030361e-09!GO:0012501;programmed cell death;5.506182470882e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;6.65418348636081e-09!GO:0009150;purine ribonucleotide metabolic process;6.86744698999147e-09!GO:0048523;negative regulation of cellular process;7.75427820181568e-09!GO:0006164;purine nucleotide biosynthetic process;9.49951450443336e-09!GO:0009260;ribonucleotide biosynthetic process;1.01573843296379e-08!GO:0006915;apoptosis;1.0398840827683e-08!GO:0008026;ATP-dependent helicase activity;1.2046551268356e-08!GO:0000074;regulation of progression through cell cycle;1.25137460466365e-08!GO:0051726;regulation of cell cycle;1.47462649432555e-08!GO:0009152;purine ribonucleotide biosynthetic process;1.68067221944889e-08!GO:0006399;tRNA metabolic process;1.68067221944889e-08!GO:0005768;endosome;2.07168646095742e-08!GO:0003924;GTPase activity;2.62703568452271e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;3.10017594513601e-08!GO:0030120;vesicle coat;3.11081099601967e-08!GO:0030662;coated vesicle membrane;3.11081099601967e-08!GO:0015630;microtubule cytoskeleton;3.2277235733517e-08!GO:0016881;acid-amino acid ligase activity;3.47628010748751e-08!GO:0008219;cell death;3.80190028186766e-08!GO:0016265;death;3.80190028186766e-08!GO:0006260;DNA replication;3.83962365011125e-08!GO:0050789;regulation of biological process;4.26420120155783e-08!GO:0043687;post-translational protein modification;4.28408476052045e-08!GO:0009199;ribonucleoside triphosphate metabolic process;4.36846229794925e-08!GO:0009060;aerobic respiration;5.97802768948022e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;6.33352721468091e-08!GO:0009144;purine nucleoside triphosphate metabolic process;6.33352721468091e-08!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;6.75220231240536e-08!GO:0004812;aminoacyl-tRNA ligase activity;6.75220231240536e-08!GO:0016875;ligase activity, forming carbon-oxygen bonds;6.75220231240536e-08!GO:0009141;nucleoside triphosphate metabolic process;6.86494208982862e-08!GO:0045333;cellular respiration;6.87320119409838e-08!GO:0000279;M phase;8.32882737651841e-08!GO:0043038;amino acid activation;9.55293143340224e-08!GO:0006418;tRNA aminoacylation for protein translation;9.55293143340224e-08!GO:0043039;tRNA aminoacylation;9.55293143340224e-08!GO:0015986;ATP synthesis coupled proton transport;9.95310285167056e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;9.95310285167056e-08!GO:0065002;intracellular protein transport across a membrane;1.21131361565335e-07!GO:0048475;coated membrane;1.25581492866467e-07!GO:0030117;membrane coat;1.25581492866467e-07!GO:0051246;regulation of protein metabolic process;1.42409984476187e-07!GO:0005788;endoplasmic reticulum lumen;1.63836869934492e-07!GO:0005643;nuclear pore;1.68324583756606e-07!GO:0065004;protein-DNA complex assembly;1.7184521209741e-07!GO:0009142;nucleoside triphosphate biosynthetic process;1.94418939056126e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.94418939056126e-07!GO:0017038;protein import;2.24969515861577e-07!GO:0030532;small nuclear ribonucleoprotein complex;2.50230452069672e-07!GO:0006403;RNA localization;2.71541875735614e-07!GO:0019222;regulation of metabolic process;2.79191755479454e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;2.79191755479454e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;2.79191755479454e-07!GO:0050657;nucleic acid transport;2.92808921546871e-07!GO:0051236;establishment of RNA localization;2.92808921546871e-07!GO:0050658;RNA transport;2.92808921546871e-07!GO:0048519;negative regulation of biological process;3.41656273284844e-07!GO:0051187;cofactor catabolic process;3.5374006119514e-07!GO:0046034;ATP metabolic process;3.78193140309286e-07!GO:0006099;tricarboxylic acid cycle;4.06612033103649e-07!GO:0046356;acetyl-CoA catabolic process;4.06612033103649e-07!GO:0006364;rRNA processing;6.01513426382423e-07!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;6.34851339320593e-07!GO:0003697;single-stranded DNA binding;6.94101318891083e-07!GO:0019829;cation-transporting ATPase activity;7.54161084008365e-07!GO:0009109;coenzyme catabolic process;7.75680581362359e-07!GO:0043566;structure-specific DNA binding;8.01521196060984e-07!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;9.74957121003087e-07!GO:0006333;chromatin assembly or disassembly;9.96356716882245e-07!GO:0016072;rRNA metabolic process;1.08767807636921e-06!GO:0000245;spliceosome assembly;1.09859088209096e-06!GO:0005667;transcription factor complex;1.22088346928256e-06!GO:0009056;catabolic process;1.25146064296606e-06!GO:0015078;hydrogen ion transmembrane transporter activity;1.28618485916976e-06!GO:0044431;Golgi apparatus part;1.3498092742238e-06!GO:0006754;ATP biosynthetic process;1.51690463884344e-06!GO:0006753;nucleoside phosphate metabolic process;1.51690463884344e-06!GO:0030036;actin cytoskeleton organization and biogenesis;1.80529059921366e-06!GO:0046930;pore complex;1.85500419228393e-06!GO:0044440;endosomal part;2.01217199928177e-06!GO:0010008;endosome membrane;2.01217199928177e-06!GO:0000785;chromatin;2.15872466809583e-06!GO:0006084;acetyl-CoA metabolic process;2.19520080145352e-06!GO:0005839;proteasome core complex (sensu Eukaryota);2.19520080145352e-06!GO:0005813;centrosome;2.25350233476895e-06!GO:0031324;negative regulation of cellular metabolic process;2.38460526802439e-06!GO:0016491;oxidoreductase activity;2.47130788634857e-06!GO:0016469;proton-transporting two-sector ATPase complex;2.57587934515909e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;2.87455599800612e-06!GO:0032446;protein modification by small protein conjugation;3.03505747974188e-06!GO:0003713;transcription coactivator activity;3.08837094359382e-06!GO:0006613;cotranslational protein targeting to membrane;3.64103944064492e-06!GO:0003714;transcription corepressor activity;3.67200261891956e-06!GO:0016023;cytoplasmic membrane-bound vesicle;3.71738355028115e-06!GO:0031988;membrane-bound vesicle;3.80659805212495e-06!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;3.81401067153135e-06!GO:0000151;ubiquitin ligase complex;3.85223216538539e-06!GO:0051789;response to protein stimulus;4.22439255986233e-06!GO:0006986;response to unfolded protein;4.22439255986233e-06!GO:0031252;leading edge;4.59280230192238e-06!GO:0005798;Golgi-associated vesicle;4.80031881348399e-06!GO:0016568;chromatin modification;5.37764057619065e-06!GO:0016567;protein ubiquitination;5.73910061755303e-06!GO:0043067;regulation of programmed cell death;5.7722737582861e-06!GO:0045259;proton-transporting ATP synthase complex;6.15294577382578e-06!GO:0005815;microtubule organizing center;6.31982596317883e-06!GO:0042981;regulation of apoptosis;6.42136098065405e-06!GO:0005525;GTP binding;7.04930622304654e-06!GO:0051028;mRNA transport;7.25977438321928e-06!GO:0051188;cofactor biosynthetic process;8.19872440842066e-06!GO:0006916;anti-apoptosis;8.34007749483772e-06!GO:0016564;transcription repressor activity;8.70755647328675e-06!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;1.01592268031886e-05!GO:0016563;transcription activator activity;1.04399850218952e-05!GO:0004298;threonine endopeptidase activity;1.04399850218952e-05!GO:0009117;nucleotide metabolic process;1.0554354273573e-05!GO:0043069;negative regulation of programmed cell death;1.10918019032538e-05!GO:0016853;isomerase activity;1.13334005211756e-05!GO:0007010;cytoskeleton organization and biogenesis;1.26146097057322e-05!GO:0009892;negative regulation of metabolic process;1.2618087728536e-05!GO:0003724;RNA helicase activity;1.394222302105e-05!GO:0016859;cis-trans isomerase activity;1.47401407640902e-05!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;1.5995273538418e-05!GO:0008361;regulation of cell size;1.86238968331799e-05!GO:0043066;negative regulation of apoptosis;1.98783613863718e-05!GO:0005769;early endosome;2.0941852292884e-05!GO:0031982;vesicle;2.0941852292884e-05!GO:0051170;nuclear import;2.20646373603012e-05!GO:0016049;cell growth;2.25801341659785e-05!GO:0031410;cytoplasmic vesicle;2.31724860573161e-05!GO:0019899;enzyme binding;2.57881516530253e-05!GO:0006752;group transfer coenzyme metabolic process;2.60557431309436e-05!GO:0030867;rough endoplasmic reticulum membrane;2.73290130246875e-05!GO:0030029;actin filament-based process;2.858012057504e-05!GO:0016779;nucleotidyltransferase activity;2.87683894681482e-05!GO:0007005;mitochondrion organization and biogenesis;3.14777882440321e-05!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;3.51750167052255e-05!GO:0006357;regulation of transcription from RNA polymerase II promoter;3.64192394060693e-05!GO:0005770;late endosome;3.93225606764459e-05!GO:0006606;protein import into nucleus;3.97371118798007e-05!GO:0005773;vacuole;4.21814407873201e-05!GO:0019843;rRNA binding;4.21814407873201e-05!GO:0045786;negative regulation of progression through cell cycle;4.27606197178507e-05!GO:0005819;spindle;4.89617680522806e-05!GO:0032561;guanyl ribonucleotide binding;5.00079862756897e-05!GO:0019001;guanyl nucleotide binding;5.00079862756897e-05!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;5.0663287887348e-05!GO:0006334;nucleosome assembly;5.99926358145611e-05!GO:0000139;Golgi membrane;6.013007012435e-05!GO:0030133;transport vesicle;6.53597802366005e-05!GO:0031323;regulation of cellular metabolic process;6.7458840716412e-05!GO:0016787;hydrolase activity;6.99549568710952e-05!GO:0015077;monovalent inorganic cation transmembrane transporter activity;7.74273701041938e-05!GO:0065007;biological regulation;8.04234797163482e-05!GO:0006612;protein targeting to membrane;8.2801988704437e-05!GO:0009108;coenzyme biosynthetic process;8.90984192560817e-05!GO:0015980;energy derivation by oxidation of organic compounds;8.94101199315699e-05!GO:0043021;ribonucleoprotein binding;0.000103044960599613!GO:0016481;negative regulation of transcription;0.000116839695074302!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.000123254002915263!GO:0016363;nuclear matrix;0.000125987055140792!GO:0001558;regulation of cell growth;0.000126815251071867!GO:0045454;cell redox homeostasis;0.000135315847277897!GO:0006091;generation of precursor metabolites and energy;0.000142956614043526!GO:0031497;chromatin assembly;0.000146191902740379!GO:0043623;cellular protein complex assembly;0.000147679756166493!GO:0005762;mitochondrial large ribosomal subunit;0.000159892822488428!GO:0000315;organellar large ribosomal subunit;0.000159892822488428!GO:0008092;cytoskeletal protein binding;0.000164023432471218!GO:0051427;hormone receptor binding;0.000195143749576974!GO:0033116;ER-Golgi intermediate compartment membrane;0.000199897465995156!GO:0006350;transcription;0.000215730265264529!GO:0006793;phosphorus metabolic process;0.000217716227236204!GO:0006796;phosphate metabolic process;0.000217716227236204!GO:0005905;coated pit;0.000230252694247984!GO:0003899;DNA-directed RNA polymerase activity;0.000244268084334719!GO:0005048;signal sequence binding;0.000253876127806579!GO:0000323;lytic vacuole;0.000263407335373491!GO:0005764;lysosome;0.000263407335373491!GO:0051329;interphase of mitotic cell cycle;0.000264601064116503!GO:0051168;nuclear export;0.00027287010482482!GO:0030663;COPI coated vesicle membrane;0.000303082277498315!GO:0030126;COPI vesicle coat;0.000303082277498315!GO:0007051;spindle organization and biogenesis;0.000311944675926051!GO:0035257;nuclear hormone receptor binding;0.000389344961229422!GO:0005885;Arp2/3 protein complex;0.000402625467032388!GO:0008250;oligosaccharyl transferase complex;0.000417398119641232!GO:0008654;phospholipid biosynthetic process;0.000433523499552273!GO:0000075;cell cycle checkpoint;0.000499560386971074!GO:0006891;intra-Golgi vesicle-mediated transport;0.000499560386971074!GO:0016310;phosphorylation;0.000505050107001596!GO:0003729;mRNA binding;0.00052416129951769!GO:0004576;oligosaccharyl transferase activity;0.00054269579588722!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.000571090436339931!GO:0006414;translational elongation;0.000588554802852743!GO:0051252;regulation of RNA metabolic process;0.000593267516258559!GO:0005791;rough endoplasmic reticulum;0.000594174410839978!GO:0000314;organellar small ribosomal subunit;0.000654255947089549!GO:0005763;mitochondrial small ribosomal subunit;0.000654255947089549!GO:0048522;positive regulation of cellular process;0.000682780365986294!GO:0051325;interphase;0.000743968507264619!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000783917555704552!GO:0008186;RNA-dependent ATPase activity;0.000796523967148505!GO:0010468;regulation of gene expression;0.000811637063543049!GO:0030137;COPI-coated vesicle;0.000824563622289754!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000829930921890147!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000836473626066546!GO:0016740;transferase activity;0.000908595958241972!GO:0031968;organelle outer membrane;0.000994536337821738!GO:0051920;peroxiredoxin activity;0.000997984809878168!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.0010338248462864!GO:0008047;enzyme activator activity;0.00105357965806682!GO:0048500;signal recognition particle;0.00106707151080168!GO:0019867;outer membrane;0.00110177055466979!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00126784552156145!GO:0003690;double-stranded DNA binding;0.00129627389213961!GO:0006383;transcription from RNA polymerase III promoter;0.00132334496510329!GO:0018196;peptidyl-asparagine modification;0.00133460431845713!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00133460431845713!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00147672557811508!GO:0008154;actin polymerization and/or depolymerization;0.00162726315764284!GO:0005874;microtubule;0.00163305150089116!GO:0006261;DNA-dependent DNA replication;0.00168592747343392!GO:0030521;androgen receptor signaling pathway;0.00170810055723118!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0017150702286416!GO:0030027;lamellipodium;0.0018051458593442!GO:0007264;small GTPase mediated signal transduction;0.00180947822995146!GO:0016281;eukaryotic translation initiation factor 4F complex;0.0018639662048885!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.0019228553962279!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.0019228553962279!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.0019228553962279!GO:0030658;transport vesicle membrane;0.00193660189918543!GO:0007243;protein kinase cascade;0.00196498061537082!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.00206580165785739!GO:0016772;transferase activity, transferring phosphorus-containing groups;0.00212493925164924!GO:0004004;ATP-dependent RNA helicase activity;0.00221214273790457!GO:0005657;replication fork;0.00228820253654077!GO:0006402;mRNA catabolic process;0.00228982262014965!GO:0006626;protein targeting to mitochondrion;0.00233408161257844!GO:0030880;RNA polymerase complex;0.00238169779049175!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00253302380777489!GO:0045047;protein targeting to ER;0.00253302380777489!GO:0043284;biopolymer biosynthetic process;0.00261618506991335!GO:0043681;protein import into mitochondrion;0.00266729818863627!GO:0005741;mitochondrial outer membrane;0.00266729818863627!GO:0003682;chromatin binding;0.00266729818863627!GO:0048471;perinuclear region of cytoplasm;0.00267978054830234!GO:0000775;chromosome, pericentric region;0.00271105702482191!GO:0004177;aminopeptidase activity;0.0027375953166056!GO:0030134;ER to Golgi transport vesicle;0.00282501071735441!GO:0003684;damaged DNA binding;0.00289087444151208!GO:0030041;actin filament polymerization;0.00296586796076946!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00307551377231873!GO:0051128;regulation of cellular component organization and biogenesis;0.00310370260856577!GO:0046489;phosphoinositide biosynthetic process;0.00311950150070222!GO:0006302;double-strand break repair;0.00311950150070222!GO:0008312;7S RNA binding;0.0032010454481987!GO:0031072;heat shock protein binding;0.00344465016358069!GO:0043488;regulation of mRNA stability;0.00354377533262938!GO:0043487;regulation of RNA stability;0.00354377533262938!GO:0016044;membrane organization and biogenesis;0.00354988110627197!GO:0003711;transcription elongation regulator activity;0.00359780412130659!GO:0046474;glycerophospholipid biosynthetic process;0.00374525211567676!GO:0030127;COPII vesicle coat;0.00375776566547478!GO:0012507;ER to Golgi transport vesicle membrane;0.00375776566547478!GO:0016197;endosome transport;0.00410672628377573!GO:0031901;early endosome membrane;0.00417001693252163!GO:0009165;nucleotide biosynthetic process;0.0042479932356214!GO:0030132;clathrin coat of coated pit;0.00450001494462958!GO:0042802;identical protein binding;0.00458431802385609!GO:0017166;vinculin binding;0.00458431802385609!GO:0015631;tubulin binding;0.00463673926381601!GO:0000059;protein import into nucleus, docking;0.00469540295866676!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00487385098871596!GO:0000428;DNA-directed RNA polymerase complex;0.00487385098871596!GO:0001726;ruffle;0.00496698169681688!GO:0030118;clathrin coat;0.0050446300059888!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00533075522908921!GO:0044452;nucleolar part;0.00538793416678216!GO:0032774;RNA biosynthetic process;0.00548907145282717!GO:0003746;translation elongation factor activity;0.00552128186216026!GO:0045892;negative regulation of transcription, DNA-dependent;0.0055701493929945!GO:0000776;kinetochore;0.00567291243966855!GO:0030660;Golgi-associated vesicle membrane;0.00577036323257255!GO:0006352;transcription initiation;0.00578068660087402!GO:0031124;mRNA 3'-end processing;0.00583397189020879!GO:0008022;protein C-terminus binding;0.005987022656636!GO:0044262;cellular carbohydrate metabolic process;0.00601322185085295!GO:0050681;androgen receptor binding;0.00632350045057269!GO:0006351;transcription, DNA-dependent;0.00632802241678775!GO:0008094;DNA-dependent ATPase activity;0.00633432453379472!GO:0007050;cell cycle arrest;0.00636437129931824!GO:0032984;macromolecular complex disassembly;0.00639996668459089!GO:0005684;U2-dependent spliceosome;0.00645503794369912!GO:0048487;beta-tubulin binding;0.00688613128476197!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00695420108755325!GO:0035258;steroid hormone receptor binding;0.00698260175844713!GO:0030176;integral to endoplasmic reticulum membrane;0.00711865300823006!GO:0051087;chaperone binding;0.00722872554256835!GO:0005096;GTPase activator activity;0.00735291963131628!GO:0005869;dynactin complex;0.00737309544078295!GO:0000049;tRNA binding;0.00771103033559045!GO:0007052;mitotic spindle organization and biogenesis;0.00792304970010008!GO:0006354;RNA elongation;0.00797744668732048!GO:0051052;regulation of DNA metabolic process;0.00811029270672747!GO:0008139;nuclear localization sequence binding;0.0081438759097759!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00817544798938135!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00817544798938135!GO:0040008;regulation of growth;0.00853236452309948!GO:0051045;negative regulation of membrane protein ectodomain proteolysis;0.00861609625779736!GO:0051043;regulation of membrane protein ectodomain proteolysis;0.00861609625779736!GO:0030833;regulation of actin filament polymerization;0.00872902240288635!GO:0000339;RNA cap binding;0.00879313197816923!GO:0008180;signalosome;0.00895208395469217!GO:0006892;post-Golgi vesicle-mediated transport;0.00906585786203005!GO:0006289;nucleotide-excision repair;0.00937536556513803!GO:0051493;regulation of cytoskeleton organization and biogenesis;0.0095368465319273!GO:0033043;regulation of organelle organization and biogenesis;0.0095368465319273!GO:0043624;cellular protein complex disassembly;0.00969416829043016!GO:0031625;ubiquitin protein ligase binding;0.00973376479102809!GO:0045045;secretory pathway;0.00994855152419366!GO:0006509;membrane protein ectodomain proteolysis;0.00994855152419366!GO:0033619;membrane protein proteolysis;0.00994855152419366!GO:0003678;DNA helicase activity;0.0100941062855181!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0101764611326568!GO:0030659;cytoplasmic vesicle membrane;0.0102017050546171!GO:0015992;proton transport;0.0105997532089022!GO:0006401;RNA catabolic process;0.0105997532089022!GO:0046483;heterocycle metabolic process;0.0110108055702138!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0111840629706249!GO:0008064;regulation of actin polymerization and/or depolymerization;0.0112104799846262!GO:0006497;protein amino acid lipidation;0.0112542705191635!GO:0006818;hydrogen transport;0.0115421836835095!GO:0005862;muscle thin filament tropomyosin;0.0115512214849976!GO:0043241;protein complex disassembly;0.0117545324167038!GO:0065009;regulation of a molecular function;0.0120342827304548!GO:0000082;G1/S transition of mitotic cell cycle;0.0120447143674899!GO:0003779;actin binding;0.0122205655543504!GO:0006310;DNA recombination;0.0122418870163218!GO:0045449;regulation of transcription;0.0125485662273304!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.013091184508908!GO:0016251;general RNA polymerase II transcription factor activity;0.0132603911342136!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.0133315008854108!GO:0015399;primary active transmembrane transporter activity;0.0133315008854108!GO:0008033;tRNA processing;0.0133398294031239!GO:0006839;mitochondrial transport;0.0133398294031239!GO:0001527;microfibril;0.0137576767687435!GO:0007093;mitotic cell cycle checkpoint;0.013997572870654!GO:0051287;NAD binding;0.0143293110626013!GO:0045941;positive regulation of transcription;0.0143294894090658!GO:0045893;positive regulation of transcription, DNA-dependent;0.0145632706553317!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0146226409553049!GO:0030384;phosphoinositide metabolic process;0.015060487633699!GO:0022408;negative regulation of cell-cell adhesion;0.0150849078237764!GO:0031529;ruffle organization and biogenesis;0.0154687229790828!GO:0016272;prefoldin complex;0.0162186415825534!GO:0044433;cytoplasmic vesicle part;0.0162369070252288!GO:0006740;NADPH regeneration;0.0163673025417734!GO:0006098;pentose-phosphate shunt;0.0163673025417734!GO:0000910;cytokinesis;0.0164238864755517!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0166581541195111!GO:0031123;RNA 3'-end processing;0.0169154896988338!GO:0005832;chaperonin-containing T-complex;0.0170419019561437!GO:0009112;nucleobase metabolic process;0.0170419019561437!GO:0000786;nucleosome;0.0173350746512888!GO:0007006;mitochondrial membrane organization and biogenesis;0.0173350746512888!GO:0006595;polyamine metabolic process;0.0173350746512888!GO:0006376;mRNA splice site selection;0.0173350746512888!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0173350746512888!GO:0009116;nucleoside metabolic process;0.0177184770790129!GO:0031543;peptidyl-proline dioxygenase activity;0.0178008467301489!GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;0.0178366536232367!GO:0043022;ribosome binding;0.0182347659166649!GO:0000209;protein polyubiquitination;0.0186692629575617!GO:0007030;Golgi organization and biogenesis;0.0186692629575617!GO:0006611;protein export from nucleus;0.0188817829799183!GO:0006650;glycerophospholipid metabolic process;0.0189349385828444!GO:0043433;negative regulation of transcription factor activity;0.0189349385828444!GO:0016126;sterol biosynthetic process;0.0197696908026128!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0197696908026128!GO:0015002;heme-copper terminal oxidase activity;0.0197696908026128!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0197696908026128!GO:0004129;cytochrome-c oxidase activity;0.0197696908026128!GO:0006378;mRNA polyadenylation;0.0198734900917824!GO:0051540;metal cluster binding;0.0199316342112588!GO:0051536;iron-sulfur cluster binding;0.0199316342112588!GO:0050811;GABA receptor binding;0.019948200524794!GO:0005938;cell cortex;0.020330314228804!GO:0030518;steroid hormone receptor signaling pathway;0.0204965976808826!GO:0030119;AP-type membrane coat adaptor complex;0.0205744290558969!GO:0030032;lamellipodium biogenesis;0.0207915594591079!GO:0048518;positive regulation of biological process;0.0211794852026596!GO:0030125;clathrin vesicle coat;0.0211794852026596!GO:0030665;clathrin coated vesicle membrane;0.0211794852026596!GO:0006405;RNA export from nucleus;0.0212668316558725!GO:0019798;procollagen-proline dioxygenase activity;0.0218370828112623!GO:0005801;cis-Golgi network;0.0221999079422611!GO:0050662;coenzyme binding;0.0224289654501676!GO:0008168;methyltransferase activity;0.0225915449248042!GO:0003702;RNA polymerase II transcription factor activity;0.0233509947214405!GO:0001952;regulation of cell-matrix adhesion;0.0235044093351237!GO:0004527;exonuclease activity;0.0237819142168027!GO:0007021;tubulin folding;0.0239244681380746!GO:0042158;lipoprotein biosynthetic process;0.0241538901784261!GO:0006979;response to oxidative stress;0.0242459302559866!GO:0006506;GPI anchor biosynthetic process;0.0245551656606389!GO:0004674;protein serine/threonine kinase activity;0.0251216739329576!GO:0006950;response to stress;0.0257627084019873!GO:0006984;ER-nuclear signaling pathway;0.0258429199842531!GO:0001953;negative regulation of cell-matrix adhesion;0.0264274654735676!GO:0033673;negative regulation of kinase activity;0.026499786637921!GO:0006469;negative regulation of protein kinase activity;0.026499786637921!GO:0047485;protein N-terminus binding;0.0270125308028626!GO:0032508;DNA duplex unwinding;0.0273543916334363!GO:0032392;DNA geometric change;0.0273543916334363!GO:0012506;vesicle membrane;0.0277425384321905!GO:0016741;transferase activity, transferring one-carbon groups;0.0283501692037731!GO:0035035;histone acetyltransferase binding;0.0285172106276975!GO:0030865;cortical cytoskeleton organization and biogenesis;0.0290055139444991!GO:0005637;nuclear inner membrane;0.0293507005360941!GO:0022411;cellular component disassembly;0.0308616766403758!GO:0007034;vacuolar transport;0.0308616766403758!GO:0019206;nucleoside kinase activity;0.0310587954913147!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0311595107118146!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.0314502840555152!GO:0031418;L-ascorbic acid binding;0.0319152894104705!GO:0006505;GPI anchor metabolic process;0.0319197525738574!GO:0006007;glucose catabolic process;0.0320283462765611!GO:0008632;apoptotic program;0.0324611418650188!GO:0003756;protein disulfide isomerase activity;0.0325441592391263!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0325441592391263!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.0327746360086704!GO:0006144;purine base metabolic process;0.0327746360086704!GO:0007265;Ras protein signal transduction;0.0332637920479612!GO:0016408;C-acyltransferase activity;0.0342250908031614!GO:0007088;regulation of mitosis;0.0349516318843809!GO:0030131;clathrin adaptor complex;0.0350729340386515!GO:0022890;inorganic cation transmembrane transporter activity;0.0352620186656414!GO:0032535;regulation of cellular component size;0.0357647330868413!GO:0017015;regulation of transforming growth factor beta receptor signaling pathway;0.0358249662423036!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0362558521455693!GO:0043065;positive regulation of apoptosis;0.0369370800850495!GO:0005784;translocon complex;0.0371189390135011!GO:0051539;4 iron, 4 sulfur cluster binding;0.0372433370002808!GO:0031371;ubiquitin conjugating enzyme complex;0.0373847334201736!GO:0051348;negative regulation of transferase activity;0.0377175955161229!GO:0051271;negative regulation of cell motility;0.0381063112659125!GO:0006268;DNA unwinding during replication;0.0384463459955698!GO:0046467;membrane lipid biosynthetic process;0.0384544610690739!GO:0031902;late endosome membrane;0.0385343490423704!GO:0005669;transcription factor TFIID complex;0.0385923984008247!GO:0009967;positive regulation of signal transduction;0.0387269897200817!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.0389564416516736!GO:0005100;Rho GTPase activator activity;0.0395579508143296!GO:0005876;spindle microtubule;0.0399061047166842!GO:0032200;telomere organization and biogenesis;0.0399753312107762!GO:0000723;telomere maintenance;0.0399753312107762!GO:0008234;cysteine-type peptidase activity;0.0399753312107762!GO:0008652;amino acid biosynthetic process;0.0421447903262015!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.0427721379523572!GO:0030508;thiol-disulfide exchange intermediate activity;0.042909792179778!GO:0043068;positive regulation of programmed cell death;0.043177809424893!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0432367559320962!GO:0008097;5S rRNA binding;0.0435197478948508!GO:0007017;microtubule-based process;0.0442640882990339!GO:0006417;regulation of translation;0.0442640882990339!GO:0005586;collagen type III;0.0442742777584407!GO:0004656;procollagen-proline 4-dioxygenase activity;0.0443800004353048!GO:0031545;peptidyl-proline 4-dioxygenase activity;0.0443800004353048!GO:0003923;GPI-anchor transamidase activity;0.0445159513037695!GO:0016255;attachment of GPI anchor to protein;0.0445159513037695!GO:0042765;GPI-anchor transamidase complex;0.0445159513037695!GO:0046914;transition metal ion binding;0.0448635086021806!GO:0000096;sulfur amino acid metabolic process;0.0452396058384547!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0458640745037305!GO:0007179;transforming growth factor beta receptor signaling pathway;0.0461604593026989!GO:0043130;ubiquitin binding;0.0461604593026989!GO:0032182;small conjugating protein binding;0.0461604593026989!GO:0042770;DNA damage response, signal transduction;0.0464558707335594!GO:0006220;pyrimidine nucleotide metabolic process;0.0464707474983896!GO:0008475;procollagen-lysine 5-dioxygenase activity;0.0466939443110098!GO:0031461;cullin-RING ubiquitin ligase complex;0.0468131680198882!GO:0030832;regulation of actin filament length;0.0468131680198882!GO:0000118;histone deacetylase complex;0.0469854634223138!GO:0009303;rRNA transcription;0.0471287628942838!GO:0016584;nucleosome positioning;0.0472843971685091!GO:0003677;DNA binding;0.0476911632856433!GO:0005595;collagen type XII;0.0479387002460237!GO:0006607;NLS-bearing substrate import into nucleus;0.0479387002460237!GO:0045792;negative regulation of cell size;0.0481189032539278!GO:0017134;fibroblast growth factor binding;0.0482112176987215!GO:0006338;chromatin remodeling;0.0482848292116629!GO:0032956;regulation of actin cytoskeleton organization and biogenesis;0.0484361766733347!GO:0051101;regulation of DNA binding;0.0486946637340705!GO:0030911;TPR domain binding;0.0493990399293589!GO:0031272;regulation of pseudopodium formation;0.049928500388449!GO:0031269;pseudopodium formation;0.049928500388449!GO:0031344;regulation of cell projection organization and biogenesis;0.049928500388449!GO:0031268;pseudopodium organization and biogenesis;0.049928500388449!GO:0031346;positive regulation of cell projection organization and biogenesis;0.049928500388449!GO:0031274;positive regulation of pseudopodium formation;0.049928500388449 | |||
|sample_id=11560 | |||
|sample_note=Originally library704 tailing failed, the remaining sample is being rerun | |||
|sample_sex=M | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=skin | |||
|top_motifs=HBP1_HMGB_SSRP1_UBTF:1.91603984986;ZNF238:1.89125222075;GZF1:1.84968333796;NKX2-2,8:1.68557104435;XBP1:1.48386438007;TAL1_TCF{3,4,12}:1.46013285035;NKX3-1:1.44377022629;NKX3-2:1.32902196339;ESR1:1.26952104397;TEAD1:1.16155867113;KLF4:1.15624177582;ALX4:1.07359651645;PAX1,9:1.05415072625;MYBL2:1.03326677184;HSF1,2:0.984103241421;NR3C1:0.980002141478;TFAP4:0.979835507069;HOX{A5,B5}:0.979182405885;EN1,2:0.946734398849;UFEwm:0.930780606464;HES1:0.871332499934;TP53:0.857322962268;SOX17:0.843496471674;TBX4,5:0.843021221042;HAND1,2:0.829530140165;GFI1B:0.819372821647;NFIX:0.811797874449;GCM1,2:0.804019230789;PDX1:0.795253702683;HMX1:0.794960964583;RXRA_VDR{dimer}:0.756285713157;MAFB:0.743002958677;GFI1:0.738456871415;GTF2I:0.721018821966;NR1H4:0.717219456706;MZF1:0.71660010771;TFAP2{A,C}:0.692530406553;NFATC1..3:0.648773221699;HMGA1,2:0.641324091532;CRX:0.626567508761;SRF:0.621283406229;HIF1A:0.620715449883;STAT1,3:0.609775053978;NANOG{mouse}:0.609126257625;RXR{A,B,G}:0.608254501846;NKX6-1,2:0.594625191618;NFE2L1:0.545091317954;GATA4:0.544767308421;AHR_ARNT_ARNT2:0.539653442471;ELK1,4_GABP{A,B1}:0.531597691821;TLX1..3_NFIC{dimer}:0.516184100029;YY1:0.496551783864;MTE{core}:0.481371111638;ATF6:0.460405410426;SPZ1:0.452806516143;MYB:0.417969837857;PATZ1:0.401956927351;TFDP1:0.394630521955;XCPE1{core}:0.3871023883;PRDM1:0.385943541098;POU3F1..4:0.385425074832;FOX{I1,J2}:0.379689990797;ALX1:0.375852071338;SMAD1..7,9:0.363180204979;NRF1:0.357343454925;PRRX1,2:0.355715605587;HOX{A4,D4}:0.354101299847;TFCP2:0.350327463165;ZNF384:0.347261323495;ZBTB6:0.338552585638;ZIC1..3:0.331045592015;EVI1:0.324371116751;MAZ:0.320894384643;ZNF148:0.317976320115;GLI1..3:0.31166586274;PAX5:0.310370504074;PAX8:0.285484609943;IKZF1:0.280693794505;HLF:0.267381213434;FOXD3:0.265910227602;TFAP2B:0.249902293626;EBF1:0.23956251006;CEBPA,B_DDIT3:0.238514808323;NFE2L2:0.216937087004;FOXO1,3,4:0.192872248482;ARID5B:0.188631527112;BACH2:0.185692611316;ZNF143:0.166121558109;MYFfamily:0.162652757365;LEF1_TCF7_TCF7L1,2:0.156217073486;E2F1..5:0.152690676983;MTF1:0.138865986056;GTF2A1,2:0.131375949642;FOXL1:0.125776547499;IRF1,2:0.113897925511;DBP:0.107849893958;FOS_FOS{B,L1}_JUN{B,D}:0.103153974993;NFE2:0.101564757375;RREB1:0.0918995363522;NKX2-3_NKX2-5:0.07380494598;LHX3,4:0.0559503699551;RUNX1..3:0.0346348751123;TEF:-0.000319833403502;POU5F1:-0.00736163130815;EGR1..3:-0.0095196357259;NHLH1,2:-0.00954759661584;PAX3,7:-0.0137867087784;TOPORS:-0.0206624200896;ZFP161:-0.0246958828118;HNF1A:-0.0361475344472;HOX{A6,A7,B6,B7}:-0.0454489645834;AIRE:-0.0761989134082;RFX1:-0.0784930880124;BPTF:-0.0892755194665;ADNP_IRX_SIX_ZHX:-0.0912770847878;TLX2:-0.0939143245837;TBP:-0.109454369922;MED-1{core}:-0.121317893186;DMAP1_NCOR{1,2}_SMARC:-0.126790924103;POU1F1:-0.128519548414;SOX5:-0.129451891416;FOXA2:-0.131697850612;STAT2,4,6:-0.131705399115;ZNF423:-0.134554168151;ELF1,2,4:-0.138668262615;NR6A1:-0.139251284108;CDC5L:-0.149060276063;PBX1:-0.168441486319;FOXM1:-0.183353700142;HIC1:-0.198796964937;MEF2{A,B,C,D}:-0.208972042436;FOSL2:-0.2110124243;SP1:-0.216551110532;bHLH_family:-0.244886126417;FOX{D1,D2}:-0.270998149117;EP300:-0.293738161849;NFIL3:-0.308847078098;FOXN1:-0.315321401097;NKX2-1,4:-0.330733714203;AR:-0.336671937978;HNF4A_NR2F1,2:-0.340207438402;TGIF1:-0.344873829953;REST:-0.349341484162;NFY{A,B,C}:-0.3501227058;SPI1:-0.358172901525;CREB1:-0.364973188442;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.36671926744;IRF7:-0.383209624514;NFKB1_REL_RELA:-0.392766796851;PPARG:-0.404442306252;ONECUT1,2:-0.417239648692;PAX2:-0.418526717876;ETS1,2:-0.432892385211;RBPJ:-0.435812945183;BREu{core}:-0.446404440395;ATF5_CREB3:-0.479147087995;SPIB:-0.49150607869;SOX2:-0.494391837445;NANOG:-0.517597917542;T:-0.521821862652;SREBF1,2:-0.531027187371;JUN:-0.539030629059;CUX2:-0.54825766829;ESRRA:-0.590944201083;STAT5{A,B}:-0.597189916281;POU6F1:-0.601313905661;ZBTB16:-0.619804898022;ATF4:-0.627451908452;FOXP1:-0.635431680314;VSX1,2:-0.663726641378;RFX2..5_RFXANK_RFXAP:-0.687308926619;ATF2:-0.697078294654;GATA6:-0.707002924573;FOXQ1:-0.71903268109;FOXP3:-0.768273662468;CDX1,2,4:-0.78143294309;PAX4:-0.78567686705;OCT4_SOX2{dimer}:-0.789715913282;SOX{8,9,10}:-0.80608611362;NR5A1,2:-0.83780725252;ZEB1:-0.843315756639;PAX6:-0.856131424414;SNAI1..3:-0.866914487834;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.878664604424;POU2F1..3:-0.884256957196;PITX1..3:-0.932779729148;FOX{F1,F2,J1}:-0.944380191615;HOXA9_MEIS1:-0.954397946545;RORA:-1.01053154738;IKZF2:-1.15637128274;LMO2:-1.32655330165;MYOD1:-1.4637426589 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11560-120D3;search_select_hide=table117:FF:11560-120D3 | |||
}} | }} |
Latest revision as of 18:09, 4 June 2020
Name: | Fibroblast - skin dystrophia myotonica, donor3 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs11913 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11913
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11913
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.525 |
10 | 10 | 0.948 |
100 | 100 | 0.399 |
101 | 101 | 0.242 |
102 | 102 | 0.0377 |
103 | 103 | 0.826 |
104 | 104 | 0.677 |
105 | 105 | 0.375 |
106 | 106 | 0.0605 |
107 | 107 | 0.469 |
108 | 108 | 0.701 |
109 | 109 | 0.7 |
11 | 11 | 0.557 |
110 | 110 | 0.64 |
111 | 111 | 0.121 |
112 | 112 | 0.968 |
113 | 113 | 9.16156e-4 |
114 | 114 | 0.907 |
115 | 115 | 0.326 |
116 | 116 | 0.615 |
117 | 117 | 0.972 |
118 | 118 | 0.765 |
119 | 119 | 0.143 |
12 | 12 | 0.32 |
120 | 120 | 0.591 |
121 | 121 | 0.508 |
122 | 122 | 0.114 |
123 | 123 | 2.09756e-5 |
124 | 124 | 0.964 |
125 | 125 | 0.83 |
126 | 126 | 0.533 |
127 | 127 | 0.452 |
128 | 128 | 0.139 |
129 | 129 | 0.509 |
13 | 13 | 0.311 |
130 | 130 | 0.0821 |
131 | 131 | 0.635 |
132 | 132 | 0.497 |
133 | 133 | 0.679 |
134 | 134 | 0.39 |
135 | 135 | 0.44 |
136 | 136 | 0.152 |
137 | 137 | 0.371 |
138 | 138 | 0.424 |
139 | 139 | 0.0422 |
14 | 14 | 0.291 |
140 | 140 | 0.293 |
141 | 141 | 0.0757 |
142 | 142 | 0.841 |
143 | 143 | 0.574 |
144 | 144 | 0.77 |
145 | 145 | 0.768 |
146 | 146 | 0.652 |
147 | 147 | 0.136 |
148 | 148 | 0.0548 |
149 | 149 | 0.101 |
15 | 15 | 0.127 |
150 | 150 | 0.372 |
151 | 151 | 0.238 |
152 | 152 | 0.365 |
153 | 153 | 0.366 |
154 | 154 | 0.754 |
155 | 155 | 0.00409 |
156 | 156 | 0.673 |
157 | 157 | 0.217 |
158 | 158 | 0.00256 |
159 | 159 | 0.363 |
16 | 16 | 0.428 |
160 | 160 | 0.792 |
161 | 161 | 0.388 |
162 | 162 | 0.658 |
163 | 163 | 0.858 |
164 | 164 | 0.993 |
165 | 165 | 0.0804 |
166 | 166 | 0.0571 |
167 | 167 | 0.348 |
168 | 168 | 0.558 |
169 | 169 | 0.111 |
17 | 17 | 0.894 |
18 | 18 | 0.353 |
19 | 19 | 0.0432 |
2 | 2 | 0.413 |
20 | 20 | 0.48 |
21 | 21 | 0.148 |
22 | 22 | 0.382 |
23 | 23 | 0.886 |
24 | 24 | 0.918 |
25 | 25 | 0.305 |
26 | 26 | 0.488 |
27 | 27 | 0.951 |
28 | 28 | 0.504 |
29 | 29 | 0.948 |
3 | 3 | 0.88 |
30 | 30 | 0.138 |
31 | 31 | 0.717 |
32 | 32 | 1.68831e-9 |
33 | 33 | 0.58 |
34 | 34 | 0.971 |
35 | 35 | 0.444 |
36 | 36 | 0.0399 |
37 | 37 | 0.191 |
38 | 38 | 0.297 |
39 | 39 | 0.543 |
4 | 4 | 0.418 |
40 | 40 | 0.0217 |
41 | 41 | 0.558 |
42 | 42 | 0.72 |
43 | 43 | 0.259 |
44 | 44 | 0.547 |
45 | 45 | 0.569 |
46 | 46 | 0.816 |
47 | 47 | 0.462 |
48 | 48 | 0.544 |
49 | 49 | 0.0749 |
5 | 5 | 0.76 |
50 | 50 | 0.607 |
51 | 51 | 0.743 |
52 | 52 | 0.53 |
53 | 53 | 0.223 |
54 | 54 | 0.781 |
55 | 55 | 0.19 |
56 | 56 | 0.868 |
57 | 57 | 0.884 |
58 | 58 | 0.11 |
59 | 59 | 0.531 |
6 | 6 | 0.266 |
60 | 60 | 0.124 |
61 | 61 | 0.766 |
62 | 62 | 0.317 |
63 | 63 | 0.754 |
64 | 64 | 0.422 |
65 | 65 | 0.578 |
66 | 66 | 0.848 |
67 | 67 | 0.642 |
68 | 68 | 0.944 |
69 | 69 | 0.734 |
7 | 7 | 0.11 |
70 | 70 | 0.361 |
71 | 71 | 0.69 |
72 | 72 | 0.434 |
73 | 73 | 0.393 |
74 | 74 | 0.246 |
75 | 75 | 0.726 |
76 | 76 | 0.955 |
77 | 77 | 0.212 |
78 | 78 | 0.102 |
79 | 79 | 0.0857 |
8 | 8 | 0.695 |
80 | 80 | 0.798 |
81 | 81 | 0.37 |
82 | 82 | 0.472 |
83 | 83 | 0.0952 |
84 | 84 | 0.38 |
85 | 85 | 0.265 |
86 | 86 | 0.473 |
87 | 87 | 0.373 |
88 | 88 | 0.559 |
89 | 89 | 0.787 |
9 | 9 | 0.552 |
90 | 90 | 0.656 |
91 | 91 | 0.568 |
92 | 92 | 0.541 |
93 | 93 | 0.783 |
94 | 94 | 0.787 |
95 | 95 | 0.738 |
96 | 96 | 0.909 |
97 | 97 | 0.484 |
98 | 98 | 0.105 |
99 | 99 | 0.0143 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11913
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000253 human fibroblast- skin dystrophia myotonica sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0002320 (connective tissue cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
0000057 (fibroblast)
0002620 (skin fibroblast)
DOID: Disease
4 (disease)
17 (musculoskeletal system disease)
450 (myotonic disease)
7 (disease of anatomical entity)
66 (muscle tissue disease)
423 (myopathy)
0080000 (muscular disease)
11722 (myotonic dystrophy)
UBERON: Anatomy
0000468 (multi-cellular organism)
0002097 (skin of body)
0002199 (integument)
0002384 (connective tissue)
0000479 (tissue)
0000062 (organ)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0003102 (surface structure)
0002416 (integumental system)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000057 (fibroblast sample)
0000250 (human fibroblast of skin sample)
0000001 (sample)
0000253 (human fibroblast- skin dystrophia myotonica sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)