Coexpression cluster:C2341: Difference between revisions
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{{Coexpression_clusters | 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reticulum part!9.33494354018741e-06!29927;6184;811;5479$GO:0005783!endoplasmic reticulum!4.32238704894574e-05!29927;6184;811;5479$GO:0005788!endoplasmic reticulum lumen!0.00119892517736691!811;5479$GO:0048770!pigment granule!0.00121336223236269!6184;5479$GO:0042470!melanosome!0.00121336223236269!6184;5479$GO:0051082!unfolded protein binding!0.00450023955118235!811;5479$GO:0044446!intracellular organelle part!0.00450023955118235!29927;6184;811;5479$GO:0044422!organelle part!0.00450023955118235!29927;6184;811;5479$GO:0040020!regulation of meiosis!0.00450023955118235!811$GO:0044444!cytoplasmic part!0.00573535899024002!29927;6184;811;5479$GO:0006457!protein folding!0.00838247864021421!811;5479$GO:0016023!cytoplasmic membrane-bound vesicle!0.00838247864021421!6184;5479$GO:0031988!membrane-bound vesicle!0.00838247864021421!6184;5479$GO:0031410!cytoplasmic vesicle!0.0109134708244856!6184;5479$GO:0031982!vesicle!0.0109134708244856!6184;5479$GO:0005789!endoplasmic reticulum membrane!0.0112394684514031!29927;6184$GO:0042175!nuclear envelope-endoplasmic reticulum network!0.0112394684514031!29927;6184$GO:0030867!rough endoplasmic reticulum membrane!0.012370741454421!6184$GO:0006886!intracellular protein transport!0.0127422358547018!29927;811$GO:0030866!cortical actin cytoskeleton organization and biogenesis!0.0127422358547018!811$GO:0030865!cortical cytoskeleton organization and biogenesis!0.0127422358547018!811$GO:0006611!protein export from nucleus!0.0127422358547018!811$GO:0008250!oligosaccharyl transferase complex!0.0127422358547018!6184$GO:0018279!protein amino acid N-linked glycosylation via asparagine!0.0127422358547018!6184$GO:0018196!peptidyl-asparagine modification!0.0127422358547018!6184$GO:0005791!rough endoplasmic reticulum!0.0127422358547018!6184$GO:0004579!dolichyl-diphosphooligosaccharide-protein glycotransferase activity!0.0127422358547018!6184$GO:0004576!oligosaccharyl transferase activity!0.013009355382734!6184$GO:0005737!cytoplasm!0.0139458562098636!29927;6184;811;5479$GO:0022884!macromolecule transmembrane transporter activity!0.0169667838835292!29927$GO:0015450!P-P-bond-hydrolysis-driven protein transmembrane transporter activity!0.0169667838835292!29927$GO:0008320!protein transmembrane transporter activity!0.0176993602305049!29927$GO:0015031!protein transport!0.0196169772724579!29927;811$GO:0046907!intracellular transport!0.0202639729663448!29927;811$GO:0045184!establishment of protein localization!0.0202639729663448!29927;811$GO:0043231!intracellular membrane-bound organelle!0.0202639729663448!29927;6184;811;5479$GO:0043227!membrane-bound organelle!0.0202639729663448!29927;6184;811;5479$GO:0008104!protein localization!0.0202639729663448!29927;811$GO:0031974!membrane-enclosed lumen!0.0202639729663448!811;5479$GO:0043233!organelle lumen!0.0202639729663448!811;5479$GO:0005515!protein binding!0.02060231316098!29927;6184;811;5479$GO:0033036!macromolecule localization!0.02060231316098!29927;811$GO:0051168!nuclear export!0.02060231316098!811$GO:0012505!endomembrane system!0.02060231316098!29927;6184$GO:0009897!external side of plasma membrane!0.0224202744666166!811$GO:0051649!establishment of cellular localization!0.0224202744666166!29927;811$GO:0006487!protein amino acid N-linked glycosylation!0.022571110402564!6184$GO:0051641!cellular localization!0.022571110402564!29927;811$GO:0009306!protein secretion!0.0235002266741561!29927$GO:0051327!M phase of meiotic cell cycle!0.0267922280755042!811$GO:0065002!intracellular protein transport across a membrane!0.0267922280755042!29927$GO:0007126!meiosis!0.0267922280755042!811$GO:0051321!meiotic cell cycle!0.0270462586568967!811$GO:0043229!intracellular organelle!0.0315541271581508!29927;6184;811;5479$GO:0043226!organelle!0.0315541271581508!29927;6184;811;5479$GO:0003755!peptidyl-prolyl cis-trans isomerase activity!0.0329087021205927!5479$GO:0016859!cis-trans isomerase activity!0.0329087021205927!5479$GO:0031090!organelle membrane!0.0331285673484481!29927;6184$GO:0006874!cellular calcium ion homeostasis!0.0389554397810922!811$GO:0055074!calcium ion homeostasis!0.0389554397810922!811$GO:0018193!peptidyl-amino acid modification!0.0393270725751541!6184$GO:0006875!cellular metal ion homeostasis!0.0393270725751541!811$GO:0055065!metal ion homeostasis!0.0393270725751541!811$GO:0044267!cellular protein metabolic process!0.0418384575583755!6184;811;5479$GO:0044260!cellular macromolecule metabolic process!0.0427315939816818!6184;811;5479$GO:0009986!cell surface!0.0448250058407225!811$GO:0019538!protein metabolic process!0.0448250058407225!6184;811;5479$GO:0006913!nucleocytoplasmic transport!0.0448250058407225!811$GO:0008565!protein transporter activity!0.0448250058407225!29927$GO:0051169!nuclear transport!0.0448250058407225!811$GO:0006486!protein amino acid glycosylation!0.0483741220471638!6184$GO:0043413!biopolymer glycosylation!0.0483741220471638!6184$GO:0030005!cellular di-, tri-valent inorganic cation homeostasis!0.0483741220471638!811$GO:0044424!intracellular part!0.0483741220471638!29927;6184;811;5479$GO:0009101!glycoprotein biosynthetic process!0.0483741220471638!6184$GO:0055066!di-, tri-valent inorganic cation homeostasis!0.0483741220471638!811|id=C2341|ontology_enrichment_celltype=CL:0000548!1.78e-44!679;CL:0000255!1.78e-44!679;CL:0002371!1.60e-39!588;CL:0000003!1.11e-25!722;CL:0000222!7.96e-24!121;CL:0002321!5.14e-22!250;CL:0000183!1.14e-19!59;CL:0000057!1.81e-18!76;CL:0000680!4.20e-18!58;CL:0000056!4.20e-18!58;CL:0000355!4.20e-18!58;CL:0000187!1.71e-17!55;CL:0000192!4.82e-17!43;CL:0000514!4.82e-17!43;CL:0000048!2.75e-15!427;CL:0000723!4.40e-15!433;CL:0000359!2.15e-14!32;CL:0000055!2.63e-14!106;CL:0000393!1.08e-13!61;CL:0000211!1.08e-13!61;CL:0000034!1.49e-13!441;CL:0000066!4.83e-07!253;CL:0002620!6.21e-07!23;CL:0000213!9.38e-07!58;CL:0000215!9.38e-07!58|ontology_enrichment_disease=|ontology_enrichment_uberon=UBERON:0003914!1.37e-21!117;UBERON:0000490!1.48e-19!148;UBERON:0005256!2.06e-19!122;UBERON:0007503!2.51e-19!78;UBERON:0003104!6.74e-19!160;UBERON:0009142!6.74e-19!160;UBERON:0000486!3.17e-17!83;UBERON:0002049!6.26e-17!78;UBERON:0007798!6.26e-17!78;UBERON:0002100!1.00e-16!199;UBERON:0002329!1.58e-16!71;UBERON:0003059!1.58e-16!71;UBERON:0007282!1.58e-16!71;UBERON:0004290!1.58e-16!71;UBERON:0009618!1.58e-16!71;UBERON:0001637!2.71e-16!42;UBERON:0003509!2.71e-16!42;UBERON:0004572!2.71e-16!42;UBERON:0007524!6.19e-16!73;UBERON:0003077!1.24e-15!72;UBERON:0007285!1.24e-15!72;UBERON:0000055!2.97e-15!68;UBERON:0001134!1.06e-14!62;UBERON:0002036!1.06e-14!62;UBERON:0003082!1.06e-14!62;UBERON:0004872!1.18e-14!83;UBERON:0007500!2.10e-14!59;UBERON:0001981!2.10e-14!59;UBERON:0004537!2.10e-14!59;UBERON:0006965!2.10e-14!59;UBERON:0000475!2.37e-14!264;UBERON:0004573!2.16e-13!33;UBERON:0004571!2.16e-13!33;UBERON:0002385!2.68e-13!64;UBERON:0001015!2.68e-13!64;UBERON:0000383!2.68e-13!64;UBERON:0004535!1.51e-11!109;UBERON:0001009!1.06e-10!112;UBERON:0000926!1.37e-09!315;UBERON:0004120!1.37e-09!315;UBERON:0006603!1.37e-09!315;UBERON:0009569!1.01e-07!112;UBERON:0002199!1.41e-07!46;UBERON:0002416!1.41e-07!46;UBERON:0003102!3.54e-07!99;UBERON:0000947!4.39e-07!21;UBERON:0010191!4.39e-07!21;UBERON:0002417!6.01e-07!60;UBERON:0000916!6.01e-07!60|pathway_enrichment=7.83254338792028e-07;0.000495799996455354;3;167;Protein processing in endoplasmic reticulum (KEGG):04141!0.000176767794609482;0.0223788027975604;2;156;Phagosome (KEGG):04145!5.131046541619e-06;0.00162397623042241;3;312;Diabetes pathways (Reactome):REACT_15380!1.44809941098012e-05;0.00229161731787605;3;441;AR up reg. targets (Netpath):NetPath_2!8.74889515724365e-06;0.00184601687817841;2;35;{INS,35} (Static 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Latest revision as of 12:03, 17 September 2013
Full id: C2341_Smooth_Fibroblast_mesenchymal_Hepatic_Adipocyte_Pericytes_Preadipocyte
Phase1 CAGE Peaks
| Hg19::chr15:64455164..64455227,- | p1@PPIB |
| Hg19::chr19:13049413..13049432,+ | p1@CALR |
| Hg19::chr3:127771233..127771316,+ | p1@SEC61A1 |
| Hg19::chr3:128369643..128369678,- | p1@RPN1 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| p.value | FDR | nGenes | nPathway | Name |
|---|---|---|---|---|
| 7.83254338792028e-07 | 0.000495799996455354 | 3 | 167 | Protein processing in endoplasmic reticulum (KEGG):04141 |
| 0.000176767794609482 | 0.0223788027975604 | 2 | 156 | Phagosome (KEGG):04145 |
| 5.131046541619e-06 | 0.00162397623042241 | 3 | 312 | Diabetes pathways (Reactome):REACT_15380 |
| 1.44809941098012e-05 | 0.00229161731787605 | 3 | 441 | AR up reg. targets (Netpath):NetPath_2 |
| 8.74889515724365e-06 | 0.00184601687817841 | 2 | 35 | {INS,35} (Static Module):NA |
Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0044432 | endoplasmic reticulum part | 9.33494354018741e-06 |
| GO:0005783 | endoplasmic reticulum | 4.32238704894574e-05 |
| GO:0005788 | endoplasmic reticulum lumen | 0.00119892517736691 |
| GO:0048770 | pigment granule | 0.00121336223236269 |
| GO:0042470 | melanosome | 0.00121336223236269 |
| GO:0051082 | unfolded protein binding | 0.00450023955118235 |
| GO:0044446 | intracellular organelle part | 0.00450023955118235 |
| GO:0044422 | organelle part | 0.00450023955118235 |
| GO:0040020 | regulation of meiosis | 0.00450023955118235 |
| GO:0044444 | cytoplasmic part | 0.00573535899024002 |
| GO:0006457 | protein folding | 0.00838247864021421 |
| GO:0016023 | cytoplasmic membrane-bound vesicle | 0.00838247864021421 |
| GO:0031988 | membrane-bound vesicle | 0.00838247864021421 |
| GO:0031410 | cytoplasmic vesicle | 0.0109134708244856 |
| GO:0031982 | vesicle | 0.0109134708244856 |
| GO:0005789 | endoplasmic reticulum membrane | 0.0112394684514031 |
| GO:0042175 | nuclear envelope-endoplasmic reticulum network | 0.0112394684514031 |
| GO:0030867 | rough endoplasmic reticulum membrane | 0.012370741454421 |
| GO:0006886 | intracellular protein transport | 0.0127422358547018 |
| GO:0030866 | cortical actin cytoskeleton organization and biogenesis | 0.0127422358547018 |
| GO:0030865 | cortical cytoskeleton organization and biogenesis | 0.0127422358547018 |
| GO:0006611 | protein export from nucleus | 0.0127422358547018 |
| GO:0008250 | oligosaccharyl transferase complex | 0.0127422358547018 |
| GO:0018279 | protein amino acid N-linked glycosylation via asparagine | 0.0127422358547018 |
| GO:0018196 | peptidyl-asparagine modification | 0.0127422358547018 |
| GO:0005791 | rough endoplasmic reticulum | 0.0127422358547018 |
| GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity | 0.0127422358547018 |
| GO:0004576 | oligosaccharyl transferase activity | 0.013009355382734 |
| GO:0005737 | cytoplasm | 0.0139458562098636 |
| GO:0022884 | macromolecule transmembrane transporter activity | 0.0169667838835292 |
| GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity | 0.0169667838835292 |
| GO:0008320 | protein transmembrane transporter activity | 0.0176993602305049 |
| GO:0015031 | protein transport | 0.0196169772724579 |
| GO:0046907 | intracellular transport | 0.0202639729663448 |
| GO:0045184 | establishment of protein localization | 0.0202639729663448 |
| GO:0043231 | intracellular membrane-bound organelle | 0.0202639729663448 |
| GO:0043227 | membrane-bound organelle | 0.0202639729663448 |
| GO:0008104 | protein localization | 0.0202639729663448 |
| GO:0031974 | membrane-enclosed lumen | 0.0202639729663448 |
| GO:0043233 | organelle lumen | 0.0202639729663448 |
| GO:0005515 | protein binding | 0.02060231316098 |
| GO:0033036 | macromolecule localization | 0.02060231316098 |
| GO:0051168 | nuclear export | 0.02060231316098 |
| GO:0012505 | endomembrane system | 0.02060231316098 |
| GO:0009897 | external side of plasma membrane | 0.0224202744666166 |
| GO:0051649 | establishment of cellular localization | 0.0224202744666166 |
| GO:0006487 | protein amino acid N-linked glycosylation | 0.022571110402564 |
| GO:0051641 | cellular localization | 0.022571110402564 |
| GO:0009306 | protein secretion | 0.0235002266741561 |
| GO:0051327 | M phase of meiotic cell cycle | 0.0267922280755042 |
| GO:0065002 | intracellular protein transport across a membrane | 0.0267922280755042 |
| GO:0007126 | meiosis | 0.0267922280755042 |
| GO:0051321 | meiotic cell cycle | 0.0270462586568967 |
| GO:0043229 | intracellular organelle | 0.0315541271581508 |
| GO:0043226 | organelle | 0.0315541271581508 |
| GO:0003755 | peptidyl-prolyl cis-trans isomerase activity | 0.0329087021205927 |
| GO:0016859 | cis-trans isomerase activity | 0.0329087021205927 |
| GO:0031090 | organelle membrane | 0.0331285673484481 |
| GO:0006874 | cellular calcium ion homeostasis | 0.0389554397810922 |
| GO:0055074 | calcium ion homeostasis | 0.0389554397810922 |
| GO:0018193 | peptidyl-amino acid modification | 0.0393270725751541 |
| GO:0006875 | cellular metal ion homeostasis | 0.0393270725751541 |
| GO:0055065 | metal ion homeostasis | 0.0393270725751541 |
| GO:0044267 | cellular protein metabolic process | 0.0418384575583755 |
| GO:0044260 | cellular macromolecule metabolic process | 0.0427315939816818 |
| GO:0009986 | cell surface | 0.0448250058407225 |
| GO:0019538 | protein metabolic process | 0.0448250058407225 |
| GO:0006913 | nucleocytoplasmic transport | 0.0448250058407225 |
| GO:0008565 | protein transporter activity | 0.0448250058407225 |
| GO:0051169 | nuclear transport | 0.0448250058407225 |
| GO:0006486 | protein amino acid glycosylation | 0.0483741220471638 |
| GO:0043413 | biopolymer glycosylation | 0.0483741220471638 |
| GO:0030005 | cellular di-, tri-valent inorganic cation homeostasis | 0.0483741220471638 |
| GO:0044424 | intracellular part | 0.0483741220471638 |
| GO:0009101 | glycoprotein biosynthetic process | 0.0483741220471638 |
| GO:0055066 | di-, tri-valent inorganic cation homeostasis | 0.0483741220471638 |
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| animal cell | 1.78e-44 | 679 |
| eukaryotic cell | 1.78e-44 | 679 |
| somatic cell | 1.60e-39 | 588 |
| native cell | 1.11e-25 | 722 |
| mesodermal cell | 7.96e-24 | 121 |
| embryonic cell | 5.14e-22 | 250 |
| contractile cell | 1.14e-19 | 59 |
| fibroblast | 1.81e-18 | 76 |
| muscle precursor cell | 4.20e-18 | 58 |
| myoblast | 4.20e-18 | 58 |
| multi-potent skeletal muscle stem cell | 4.20e-18 | 58 |
| muscle cell | 1.71e-17 | 55 |
| smooth muscle cell | 4.82e-17 | 43 |
| smooth muscle myoblast | 4.82e-17 | 43 |
| multi fate stem cell | 2.75e-15 | 427 |
| somatic stem cell | 4.40e-15 | 433 |
| vascular associated smooth muscle cell | 2.15e-14 | 32 |
| non-terminally differentiated cell | 2.63e-14 | 106 |
| electrically responsive cell | 1.08e-13 | 61 |
| electrically active cell | 1.08e-13 | 61 |
| stem cell | 1.49e-13 | 441 |
| epithelial cell | 4.83e-07 | 253 |
| skin fibroblast | 6.21e-07 | 23 |
| lining cell | 9.38e-07 | 58 |
| barrier cell | 9.38e-07 | 58 |
Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 4.10305 |
| MA0004.1 | 0.71247 |
| MA0006.1 | 1.31813 |
| MA0007.1 | 1.65296 |
| MA0009.1 | 1.20602 |
| MA0014.1 | 3.76953 |
| MA0017.1 | 0.577281 |
| MA0019.1 | 0.873355 |
| MA0024.1 | 1.09684 |
| MA0025.1 | 1.34373 |
| MA0027.1 | 2.83281 |
| MA0028.1 | 0.550763 |
| MA0029.1 | 1.11704 |
| MA0030.1 | 1.10506 |
| MA0031.1 | 1.03735 |
| MA0038.1 | 0.824639 |
| MA0040.1 | 1.12314 |
| MA0041.1 | 0.732902 |
| MA0042.1 | 0.697662 |
| MA0043.1 | 1.20635 |
| MA0046.1 | 1.19471 |
| MA0048.1 | 0.709734 |
| MA0050.1 | 0.69864 |
| MA0051.1 | 0.820063 |
| MA0052.1 | 1.12718 |
| MA0055.1 | 0.791759 |
| MA0056.1 | 0 |
| MA0057.1 | 0.248209 |
| MA0058.1 | 0.605914 |
| MA0059.1 | 0.604454 |
| MA0060.1 | 1.01899 |
| MA0061.1 | 0.360128 |
| MA0063.1 | 0 |
| MA0066.1 | 0.825101 |
| MA0067.1 | 1.53181 |
| MA0068.1 | 0.313194 |
| MA0069.1 | 1.19071 |
| MA0070.1 | 1.17908 |
| MA0071.1 | 0.782546 |
| MA0072.1 | 1.1744 |
| MA0073.1 | 0.380957 |
| MA0074.1 | 0.819248 |
| MA0076.1 | 0.623864 |
| MA0077.1 | 1.16637 |
| MA0078.1 | 0.926725 |
| MA0081.1 | 0.604638 |
| MA0083.1 | 1.21381 |
| MA0084.1 | 1.72172 |
| MA0087.1 | 1.17185 |
| MA0088.1 | 0.536981 |
| MA0089.1 | 0 |
| MA0090.1 | 0.640115 |
| MA0091.1 | 0.715356 |
| MA0092.1 | 0.673508 |
| MA0093.1 | 0.535768 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.83965 |
| MA0101.1 | 0.539569 |
| MA0103.1 | 0.521546 |
| MA0105.1 | 0.656404 |
| MA0106.1 | 0.869173 |
| MA0107.1 | 0.453492 |
| MA0108.2 | 1.03412 |
| MA0109.1 | 0 |
| MA0111.1 | 0.655276 |
| MA0113.1 | 0.886811 |
| MA0114.1 | 0.447443 |
| MA0115.1 | 1.45393 |
| MA0116.1 | 1.15856 |
| MA0117.1 | 1.24497 |
| MA0119.1 | 0.586221 |
| MA0122.1 | 1.27173 |
| MA0124.1 | 1.41151 |
| MA0125.1 | 1.32534 |
| MA0130.1 | 0 |
| MA0131.1 | 0.94608 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 1.23748 |
| MA0136.1 | 0.832277 |
| MA0139.1 | 2.47057 |
| MA0140.1 | 0.779643 |
| MA0141.1 | 0.602484 |
| MA0142.1 | 1.00381 |
| MA0143.1 | 0.887001 |
| MA0144.1 | 0.430413 |
| MA0145.1 | 0.195821 |
| MA0146.1 | 1.75643 |
| MA0147.1 | 1.16748 |
| MA0148.1 | 0.739888 |
| MA0149.1 | 0.769072 |
| MA0062.2 | 1.66396 |
| MA0035.2 | 0.778873 |
| MA0039.2 | 1.13403 |
| MA0138.2 | 0.928035 |
| MA0002.2 | 0.379056 |
| MA0137.2 | 0.558189 |
| MA0104.2 | 1.01696 |
| MA0047.2 | 0.856092 |
| MA0112.2 | 0.551048 |
| MA0065.2 | 0.199162 |
| MA0150.1 | 0.633493 |
| MA0151.1 | 0 |
| MA0152.1 | 0.78681 |
| MA0153.1 | 1.30799 |
| MA0154.1 | 0.229241 |
| MA0155.1 | 0.180766 |
| MA0156.1 | 0.560797 |
| MA0157.1 | 0.97481 |
| MA0158.1 | 0 |
| MA0159.1 | 0.462502 |
| MA0160.1 | 0.756582 |
| MA0161.1 | 0 |
| MA0162.1 | 1.57817 |
| MA0163.1 | 0.918944 |
| MA0164.1 | 0.90014 |
| MA0080.2 | 0.535868 |
| MA0018.2 | 0.870662 |
| MA0099.2 | 0.7872 |
| MA0079.2 | 1.11128 |
| MA0102.2 | 1.75932 |
| MA0258.1 | 0.418966 |
| MA0259.1 | 0.471671 |
| MA0442.1 | 0 |
ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data
(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)
| TF | #promoters | Enrichment | p-value | q-value |
|---|---|---|---|---|
| ATF3#467 | 2 | 11.2315872630044 | 0.0111955903992222 | 0.0411261041013107 |
| BRCA1#672 | 2 | 10.0921153216119 | 0.013771396990026 | 0.0484674281462957 |
| CCNT2#905 | 3 | 4.75215118272197 | 0.0138620699668949 | 0.048712675816707 |
| E2F1#1869 | 4 | 4.90738921487932 | 0.00172402235736179 | 0.0106396721019032 |
| E2F4#1874 | 4 | 12.6680603152844 | 3.88145892637771e-05 | 0.000725959328101651 |
| ELF1#1997 | 4 | 4.25809795880754 | 0.00304152556578124 | 0.0160756016480074 |
| ETS1#2113 | 4 | 9.72876092220234 | 0.000111595531741814 | 0.00154390326395328 |
| GABPB1#2553 | 3 | 5.30076287713663 | 0.0101267882423427 | 0.0378496094636235 |
| HEY1#23462 | 4 | 4.04011104310571 | 0.0037530463691798 | 0.0185800345919022 |
| HMGN3#9324 | 3 | 6.13391079251294 | 0.00664069668332472 | 0.0282895954033998 |
| IRF1#3659 | 3 | 5.72787281517293 | 0.00809711479033333 | 0.0320020651499573 |
| MAX#4149 | 3 | 4.83941663175534 | 0.0131573713783684 | 0.0466095485172449 |
| MXI1#4601 | 3 | 7.47117872156947 | 0.00374131473855096 | 0.018630580745698 |
| NFKB1#4790 | 4 | 5.48806342419384 | 0.00110219956630198 | 0.00767366312279263 |
| NFYA#4800 | 3 | 13.8191855248729 | 0.000613241180673451 | 0.00508626871572066 |
| NFYB#4801 | 3 | 12.5698449401523 | 0.00081145639769735 | 0.0061864146812989 |
| PAX5#5079 | 3 | 5.00217414838337 | 0.0119653317478641 | 0.0434841423347197 |
| POU2F2#5452 | 4 | 9.10612405774252 | 0.00014539566517493 | 0.00188259085980715 |
| SIN3A#25942 | 4 | 5.40888472681514 | 0.00116817238488516 | 0.00795324352705481 |
| SIX5#147912 | 3 | 12.8150365165942 | 0.000766447113693038 | 0.0060144992190989 |
| SP2#6668 | 2 | 13.0767652469223 | 0.00833003653661494 | 0.0328047015779611 |
| TAF1#6872 | 4 | 3.34304628574529 | 0.00800566489870165 | 0.0321776337883121 |
| TAF7#6879 | 3 | 8.57480205369294 | 0.0025005543351524 | 0.0140292986413635 |
| TBP#6908 | 4 | 3.70677068709639 | 0.00529637781478435 | 0.024384958675642 |
| USF1#7391 | 3 | 4.77112445790597 | 0.0137046588718802 | 0.0482927615871615 |
| ZNF143#7702 | 3 | 10.1256574141709 | 0.00153486161068818 | 0.00976304353241143 |
Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data
This analysis result is provided for C0 - C305 clusters.
