MCL coexpression mm9:3505: Difference between revisions
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{{MCL_coexpression_mm9 | 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foregut morphogenesis;0.011145798098101;11481!GO:0007440;foregut morphogenesis;0.011145798098101;11481!GO:0060021;palate development;0.011145798098101;11481!GO:0048613;embryonic ectodermal gut morphogenesis;0.011145798098101;11481!GO:0005881;cytoplasmic microtubule;0.011145798098101;269713!GO:0048611;embryonic ectodermal gut development;0.011145798098101;11481!GO:0048185;activin binding;0.011145798098101;11481!GO:0004712;protein serine/threonine/tyrosine kinase activity;0.011145798098101;11481!GO:0048558;embryonic gut morphogenesis;0.011145798098101;11481!GO:0048557;embryonic digestive tract morphogenesis;0.011145798098101;11481!GO:0007439;ectodermal gut development;0.011145798098101;11481!GO:0048567;ectodermal gut morphogenesis;0.011145798098101;11481!GO:0006367;transcription initiation from RNA polymerase II promoter;0.011145798098101;269713!GO:0048547;gut morphogenesis;0.011145798098101;11481!GO:0004675;transmembrane receptor protein serine/threonine kinase activity;0.011145798098101;11481!GO:0005024;transforming growth factor beta receptor activity;0.011145798098101;11481!GO:0048546;digestive tract morphogenesis;0.0117080755149383;11481!GO:0048566;embryonic gut development;0.0117080755149383;11481!GO:0048565;gut development;0.0153558571126666;11481!GO:0048562;embryonic organ morphogenesis;0.0170180089459955;11481!GO:0048705;skeletal morphogenesis;0.0177502380498165;11481!GO:0006352;transcription initiation;0.0184157393298989;269713!GO:0001702;gastrulation with mouth forming second;0.0212276851367173;11481!GO:0007368;determination of left/right symmetry;0.0212276851367173;11481!GO:0009799;determination of symmetry;0.0212276851367173;11481!GO:0009855;determination of bilateral symmetry;0.0212276851367173;11481!GO:0042475;odontogenesis of dentine-containing teeth;0.0212276851367173;11481!GO:0048568;embryonic organ development;0.0212276851367173;11481!GO:0042476;odontogenesis;0.0212276851367173;11481!GO:0004702;receptor signaling protein serine/threonine kinase activity;0.0247988829518103;11481!GO:0019838;growth factor binding;0.0247988829518103;11481!GO:0007498;mesoderm development;0.0247988829518103;11481!GO:0007369;gastrulation;0.0304164743280477;11481!GO:0001822;kidney development;0.0336412387697396;11481!GO:0019199;transmembrane receptor protein kinase activity;0.0336412387697396;11481!GO:0003702;RNA polymerase II transcription factor activity;0.0336412387697396;269713!GO:0001655;urogenital system development;0.0336412387697396;11481!GO:0007178;transmembrane receptor protein serine/threonine kinase signaling pathway;0.0336412387697396;11481!GO:0005057;receptor signaling protein activity;0.0356762223841759;11481!GO:0009952;anterior/posterior pattern formation;0.0380117155275296;11481!GO:0065004;protein-DNA complex assembly;0.0473082376810146;269713!GO:0030145;manganese ion 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|coexpression_dpi_cluster_scores_median=-0.0979955395173481,0.211135456043045,0.114532833167059,0.283421581467297,0.28104096365461,0.196826716984843,0.0458173750398806,-0.0771513398494975,-0.0324414512854135,0.0673910276920903,-0.49608571365662,-0.424759104463956,-0.276454257466617,-0.337683452040983,-0.261949251452682,-0.397372049393308,-0.564723440145294,-0.218592756620652,-0.318285731710067,-0.188401367084017,-0.0590549187654298,-0.087896641956004,-0.319108897428567,-0.119228764036766,-0.00529903924534902,0.160390983650748,-0.0753222494766967,0.015188828568182,-0.00120345125585208,-0.0531497130276589,0.0487058936729707,0.00398523074802415,-0.196702986155018,-0.545033083349415,-0.241612491925991,-0.0426334334353402,-0.179262761126984,-0.202577603256323,-0.136340281737228,-0.318631637110636,0.111006530800741,0.180766240165011,0.013552197067056,-0.417709430354623,-0.306801284853208,-0.325627511685544,-0.135982509651393,-0.227295933697136,-0.355891779178476,-0.467872417198711,-0.248388741614685,-0.242810361438615,-0.145351843185217,-0.327843175651702,-0.419196134925445,-0.0183428848716525,-0.0867728846806062,-0.256939925017823,0.847154126228673,0.962963948564856,1.01719503185368,0.17787777839902,-0.101208678707967,0.318248012349351,0.404889992612027,0.113207386149409,0.170502435878709,0.140008120074908,0.514135544986728,0.48159396557327,0.519753562510238,0.350147584250115,0.239776515605091,0.736004048297608,0.677952653597446,0.815134244498652,0.316487284809444,0.301370332674346,0.358163543086344,0.888152258879549,0.861825267022193,0.761901961230702,0.234945158213909,0.374876902391711,0.406571968026642,0.64836142921184,0.400949380834319,0.709330060707384,0.264680520674749,0.274856198939207,-0.346450498745873,-0.360147650086979,-0.564723440145294,-0.545033083349415,-0.347298348809033,-0.545033083349415,-0.200761399126672,-0.338969417832615,-0.444736304035916,-0.498352773076073,0.0327207272952915,-0.545033083349415,-0.545033083349415,-0.545033083349415,-0.274129784510755,-0.384227246325037,-0.326336926034976,-0.191689622609371,-0.321034783923415,-0.224768010393657,0.0504620729837086,-0.00901483664446012,0.0821386515970146,0.0222833490384315,-0.231524754447357,-0.23043217915686,0.241057913329887,-0.29595071584176,-0.545033083349415,-0.250434362539694,-0.0945595585560335,-0.0951780764705191,-0.107762919906727,-0.124336331360702,0.094297972912802,0.00581885367544288,-0.247007654625328,-0.340939503616571,-0.260111900541027,0.398911977108803,0.235464724613464,0.610890564534155,0.210327678378555,0.352831284930979,0.338583922393002,0.374089840451997,-0.303375964558083,-0.168021431399091,-0.53190458736906,-0.232811436330601,0.391379790792001,0.253462072165679,0.319635643794642,0.291334314284884,0.400808570564092,0.333994193201933,0.405216882871573,-0.13811493754401,0.498340762536728,0.36796555171316,0.233134791246527,0.024140695543982,-0.0757515857568988,-0.00875687671781833,-0.0898775887319624,0.216655932919182,-0.314019132609242,-0.384398014875107,-0.277277094280037,0.0898483017654654,0.086751984074396,-0.0452436598153056,0.0713471688751536,-0.187142136838828,-0.166925290593789,-0.185380991978836,-0.358487290063312,-0.430051891536167,-0.303984599030584,-0.266961882261072,-0.327930834162036,-0.238471528354252,-0.104690696786029,-0.288498493259312,0.171454309899717,0.193704873096242,0.168663218092596,0.0888425222970686,0.316771674686157,0.296834276243824,0.225595358543248,0.0721252281593071,0.201587289284495,0.220716361662857,0.194588561458991,0.0792960788882646,0.131820180168954,0.0133872601759988,0.077320343814095,0.175939473972981,-0.00218164747989447,-0.0608573399185642,0.184323022928491,0.232590598582416,0.325276166769588,0.209460007811619,0.122662278943367,0.0433023469661195,0.0611097893936612,-0.151264643642568,-0.191695947232142,-0.10925872355551,-0.43227643125332,-0.146814181905158,-0.312784606959774,-0.237505431751624,-0.283962377261466,-0.251734928562849,-0.24000359653663,-0.212436175294797,-0.412659826517511,-0.459362673885614,0.199591071798482,-0.233810777044696,-0.258102377977935,-0.367451062539939,-0.442748938548624,-0.336421966026242,-0.184577452125826,0.315497562780997,0.102638577247239,0.263302334247653,0.110139336973669,0.125366084361237,0.226917063892388,0.162350272309434,0.0894782464795251,0.027624767779752,0.155751976460252,0.0691681749667538,-0.0310035121551704,-0.00607825300518483,0.217297774698681,-0.124793888983826,-0.545033083349415,-0.367828448966565,0.315991644102631,0.353444694276986,-0.33230333748457,-0.241862153331871,0.348819084949214,0.295466708238623,0.424865873220618,0.0930129842831985,0.191839167448205,0.41918973601855,0.194193687579392,0.342690231078311,0.270147967096598,0.653095397306027,-0.215529301597346,-0.0444060405686911,-0.286291717267902,-0.246219130595853,-0.0668837270730448,0.164853173469828,0.063105532309637,-0.198806840873908,-0.066549449715254,-0.225409004713291,-0.0582589400494564,-0.244452247204405,-0.100599956264916,-0.340146018061809,-0.545033083349415,-0.237247163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| |||
|gostat_on_MCL_coexpression=GO:0048617;embryonic foregut morphogenesis;0.011145798098101;11481!GO:0007440;foregut morphogenesis;0.011145798098101;11481!GO:0060021;palate development;0.011145798098101;11481!GO:0048613;embryonic ectodermal gut morphogenesis;0.011145798098101;11481!GO:0005881;cytoplasmic microtubule;0.011145798098101;269713!GO:0048611;embryonic ectodermal gut development;0.011145798098101;11481!GO:0048185;activin binding;0.011145798098101;11481!GO:0004712;protein serine/threonine/tyrosine kinase activity;0.011145798098101;11481!GO:0048558;embryonic gut morphogenesis;0.011145798098101;11481!GO:0048557;embryonic digestive tract morphogenesis;0.011145798098101;11481!GO:0007439;ectodermal gut development;0.011145798098101;11481!GO:0048567;ectodermal gut morphogenesis;0.011145798098101;11481!GO:0006367;transcription initiation from RNA polymerase II promoter;0.011145798098101;269713!GO:0048547;gut morphogenesis;0.011145798098101;11481!GO:0004675;transmembrane receptor protein serine/threonine kinase activity;0.011145798098101;11481!GO:0005024;transforming growth factor beta receptor activity;0.011145798098101;11481!GO:0048546;digestive tract morphogenesis;0.0117080755149383;11481!GO:0048566;embryonic gut development;0.0117080755149383;11481!GO:0048565;gut development;0.0153558571126666;11481!GO:0048562;embryonic organ morphogenesis;0.0170180089459955;11481!GO:0048705;skeletal morphogenesis;0.0177502380498165;11481!GO:0006352;transcription initiation;0.0184157393298989;269713!GO:0001702;gastrulation with mouth forming second;0.0212276851367173;11481!GO:0007368;determination of left/right symmetry;0.0212276851367173;11481!GO:0009799;determination of symmetry;0.0212276851367173;11481!GO:0009855;determination of bilateral symmetry;0.0212276851367173;11481!GO:0042475;odontogenesis of dentine-containing teeth;0.0212276851367173;11481!GO:0048568;embryonic organ development;0.0212276851367173;11481!GO:0042476;odontogenesis;0.0212276851367173;11481!GO:0004702;receptor signaling protein serine/threonine kinase activity;0.0247988829518103;11481!GO:0019838;growth factor binding;0.0247988829518103;11481!GO:0007498;mesoderm development;0.0247988829518103;11481!GO:0007369;gastrulation;0.0304164743280477;11481!GO:0001822;kidney development;0.0336412387697396;11481!GO:0019199;transmembrane receptor protein kinase activity;0.0336412387697396;11481!GO:0003702;RNA polymerase II transcription factor activity;0.0336412387697396;269713!GO:0001655;urogenital system development;0.0336412387697396;11481!GO:0007178;transmembrane receptor protein serine/threonine kinase signaling pathway;0.0336412387697396;11481!GO:0005057;receptor signaling protein activity;0.0356762223841759;11481!GO:0009952;anterior/posterior pattern formation;0.0380117155275296;11481!GO:0065004;protein-DNA complex assembly;0.0473082376810146;269713!GO:0030145;manganese ion binding;0.0496332098555546;11481! | |||
}} |
Latest revision as of 20:12, 17 September 2013
Phase1 CAGE Peaks
Short description | |
---|---|
Mm9::chr5:135028251..135028283,- | p4@Clip2 |
Mm9::chr5:135028284..135028314,- | p2@Clip2 |
Mm9::chr9:119311199..119311271,+ | p1@Acvr2b |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0048617 | embryonic foregut morphogenesis | 0.011145798098101 |
GO:0007440 | foregut morphogenesis | 0.011145798098101 |
GO:0060021 | palate development | 0.011145798098101 |
GO:0048613 | embryonic ectodermal gut morphogenesis | 0.011145798098101 |
GO:0005881 | cytoplasmic microtubule | 0.011145798098101 |
GO:0048611 | embryonic ectodermal gut development | 0.011145798098101 |
GO:0048185 | activin binding | 0.011145798098101 |
GO:0004712 | protein serine/threonine/tyrosine kinase activity | 0.011145798098101 |
GO:0048558 | embryonic gut morphogenesis | 0.011145798098101 |
GO:0048557 | embryonic digestive tract morphogenesis | 0.011145798098101 |
GO:0007439 | ectodermal gut development | 0.011145798098101 |
GO:0048567 | ectodermal gut morphogenesis | 0.011145798098101 |
GO:0006367 | transcription initiation from RNA polymerase II promoter | 0.011145798098101 |
GO:0048547 | gut morphogenesis | 0.011145798098101 |
GO:0004675 | transmembrane receptor protein serine/threonine kinase activity | 0.011145798098101 |
GO:0005024 | transforming growth factor beta receptor activity | 0.011145798098101 |
GO:0048546 | digestive tract morphogenesis | 0.0117080755149383 |
GO:0048566 | embryonic gut development | 0.0117080755149383 |
GO:0048565 | gut development | 0.0153558571126666 |
GO:0048562 | embryonic organ morphogenesis | 0.0170180089459955 |
GO:0048705 | skeletal morphogenesis | 0.0177502380498165 |
GO:0006352 | transcription initiation | 0.0184157393298989 |
GO:0001702 | gastrulation with mouth forming second | 0.0212276851367173 |
GO:0007368 | determination of left/right symmetry | 0.0212276851367173 |
GO:0009799 | determination of symmetry | 0.0212276851367173 |
GO:0009855 | determination of bilateral symmetry | 0.0212276851367173 |
GO:0042475 | odontogenesis of dentine-containing teeth | 0.0212276851367173 |
GO:0048568 | embryonic organ development | 0.0212276851367173 |
GO:0042476 | odontogenesis | 0.0212276851367173 |
GO:0004702 | receptor signaling protein serine/threonine kinase activity | 0.0247988829518103 |
GO:0019838 | growth factor binding | 0.0247988829518103 |
GO:0007498 | mesoderm development | 0.0247988829518103 |
GO:0007369 | gastrulation | 0.0304164743280477 |
GO:0001822 | kidney development | 0.0336412387697396 |
GO:0019199 | transmembrane receptor protein kinase activity | 0.0336412387697396 |
GO:0003702 | RNA polymerase II transcription factor activity | 0.0336412387697396 |
GO:0001655 | urogenital system development | 0.0336412387697396 |
GO:0007178 | transmembrane receptor protein serine/threonine kinase signaling pathway | 0.0336412387697396 |
GO:0005057 | receptor signaling protein activity | 0.0356762223841759 |
GO:0009952 | anterior/posterior pattern formation | 0.0380117155275296 |
GO:0065004 | protein-DNA complex assembly | 0.0473082376810146 |
GO:0030145 | manganese ion binding | 0.0496332098555546 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
Ontology term | p-value | n |
---|---|---|
neuron | 1.50e-16 | 33 |
neuronal stem cell | 1.50e-16 | 33 |
neuroblast | 1.50e-16 | 33 |
electrically signaling cell | 1.50e-16 | 33 |
CNS neuron (sensu Vertebrata) | 2.61e-14 | 23 |
neuroblast (sensu Vertebrata) | 2.61e-14 | 23 |
neural cell | 3.61e-12 | 43 |
ectodermal cell | 4.92e-12 | 44 |
neurectodermal cell | 4.92e-12 | 44 |
electrically responsive cell | 1.11e-11 | 39 |
electrically active cell | 1.11e-11 | 39 |
non-terminally differentiated cell | 7.18e-09 | 49 |
Ontology term | p-value | n |
---|---|---|
nervous system | 5.01e-21 | 75 |
central nervous system | 2.97e-20 | 73 |
neurectoderm | 7.53e-18 | 64 |
neural plate | 7.53e-18 | 64 |
presumptive neural plate | 7.53e-18 | 64 |
ectoderm-derived structure | 1.30e-16 | 95 |
ectoderm | 1.30e-16 | 95 |
presumptive ectoderm | 1.30e-16 | 95 |
regional part of nervous system | 3.77e-15 | 54 |
neural tube | 3.37e-14 | 52 |
neural rod | 3.37e-14 | 52 |
future spinal cord | 3.37e-14 | 52 |
neural keel | 3.37e-14 | 52 |
pre-chordal neural plate | 6.25e-14 | 49 |
gray matter | 3.29e-12 | 34 |
ecto-epithelium | 4.29e-12 | 73 |
brain | 6.18e-12 | 47 |
future brain | 6.18e-12 | 47 |
anterior neural tube | 6.54e-12 | 40 |
regional part of forebrain | 2.09e-11 | 39 |
forebrain | 2.09e-11 | 39 |
future forebrain | 2.09e-11 | 39 |
regional part of brain | 2.29e-11 | 46 |
brain grey matter | 9.91e-10 | 29 |
regional part of telencephalon | 9.91e-10 | 29 |
telencephalon | 9.91e-10 | 29 |
structure with developmental contribution from neural crest | 5.69e-09 | 92 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 0.899234 |
MA0004.1 | 0.801718 |
MA0006.1 | 0.60285 |
MA0007.1 | 0.784593 |
MA0009.1 | 1.27673 |
MA0014.1 | 4.96439 |
MA0017.1 | 0.635031 |
MA0019.1 | 1.08369 |
MA0024.1 | 1.23079 |
MA0025.1 | 1.51835 |
MA0027.1 | 2.9431 |
MA0028.1 | 0.61552 |
MA0029.1 | 1.20789 |
MA0030.1 | 1.21482 |
MA0031.1 | 1.17722 |
MA0038.1 | 0.963265 |
MA0040.1 | 1.28983 |
MA0041.1 | 0.714279 |
MA0042.1 | 0.69885 |
MA0043.1 | 1.3775 |
MA0046.1 | 1.31428 |
MA0048.1 | 0.353763 |
MA0050.1 | 0.845669 |
MA0051.1 | 0.973068 |
MA0052.1 | 1.29825 |
MA0055.1 | 0.190475 |
MA0056.1 | 0 |
MA0057.1 | 1.60767 |
MA0058.1 | 0.690848 |
MA0059.1 | 1.68104 |
MA0060.1 | 0.502699 |
MA0061.1 | 0.5406 |
MA0063.1 | 0 |
MA0066.1 | 0.951196 |
MA0067.1 | 1.63197 |
MA0068.1 | 3.3888 |
MA0069.1 | 1.29861 |
MA0070.1 | 1.28847 |
MA0071.1 | 0.844726 |
MA0072.1 | 1.2796 |
MA0073.1 | 17.0441 |
MA0074.1 | 0.911576 |
MA0076.1 | 0.657929 |
MA0077.1 | 1.2569 |
MA0078.1 | 1.0091 |
MA0081.1 | 0.732313 |
MA0083.1 | 1.37668 |
MA0084.1 | 1.96428 |
MA0087.1 | 1.33189 |
MA0088.1 | 0.27999 |
MA0089.1 | 0 |
MA0090.1 | 1.7994 |
MA0091.1 | 0.816659 |
MA0092.1 | 0.762845 |
MA0093.1 | 0.62555 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.89873 |
MA0101.1 | 0.71579 |
MA0103.1 | 0.647985 |
MA0105.1 | 0.405648 |
MA0106.1 | 1.01755 |
MA0107.1 | 0.640607 |
MA0108.2 | 1.10817 |
MA0109.1 | 0 |
MA0111.1 | 0.778753 |
MA0113.1 | 0.986839 |
MA0114.1 | 0.537669 |
MA0115.1 | 1.38041 |
MA0116.1 | 1.46662 |
MA0117.1 | 1.34691 |
MA0119.1 | 0.716476 |
MA0122.1 | 1.36752 |
MA0124.1 | 1.57762 |
MA0125.1 | 1.5017 |
MA0130.1 | 0 |
MA0131.1 | 1.07881 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 1.4152 |
MA0136.1 | 0.933582 |
MA0139.1 | 0.462282 |
MA0140.1 | 0.898603 |
MA0141.1 | 0.671467 |
MA0142.1 | 1.16183 |
MA0143.1 | 1.00467 |
MA0144.1 | 0.541532 |
MA0145.1 | 0.292366 |
MA0146.1 | 0.46063 |
MA0147.1 | 0.556853 |
MA0148.1 | 0.820161 |
MA0149.1 | 0.722227 |
MA0062.2 | 0.412742 |
MA0035.2 | 0.903829 |
MA0039.2 | 3.91141 |
MA0138.2 | 1.07027 |
MA0002.2 | 0.466067 |
MA0137.2 | 0.668025 |
MA0104.2 | 0.48458 |
MA0047.2 | 0.962424 |
MA0112.2 | 0.29236 |
MA0065.2 | 0.292912 |
MA0150.1 | 0.784464 |
MA0151.1 | 0 |
MA0152.1 | 0.962542 |
MA0153.1 | 1.43238 |
MA0154.1 | 0.35067 |
MA0155.1 | 0.840842 |
MA0156.1 | 0.656895 |
MA0157.1 | 1.12772 |
MA0158.1 | 0 |
MA0159.1 | 0.569393 |
MA0160.1 | 0.823568 |
MA0161.1 | 0 |
MA0162.1 | 0.499274 |
MA0163.1 | 0.477233 |
MA0164.1 | 0.933981 |
MA0080.2 | 0.64167 |
MA0018.2 | 0.944669 |
MA0099.2 | 1.06348 |
MA0079.2 | 9.2373 |
MA0102.2 | 2.01714 |
MA0258.1 | 0.520639 |
MA0259.1 | 0.543506 |
MA0442.1 | 0 |