FF:11312-117C7: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00004994 | ||
| | |DRA_sample_Accession_RNASeq=sRNA-Seq@SAMD00004994 | ||
|accession_numbers=CAGE;DRX008402;DRR009274;DRZ000699;DRZ002084;DRZ012049;DRZ013434 | |||
|accession_numbers_RNASeq=sRNA-Seq;DRX037067;DRR041433;DRZ007075 | |||
|ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0000178,UBERON:0004120,UBERON:0000061,UBERON:0000465,UBERON:0000179,UBERON:0000463,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0010317,UBERON:0002390,UBERON:0004535,UBERON:0002193,UBERON:0001009 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0002371,CL:0000219,CL:0000738,CL:0002087,CL:0000255,CL:0000226,CL:0000080,CL:0000842 | |||
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|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000001,FF:0000135 | ||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr2:68592406..68592424,+!p1@PLEK!2.45!283.88!PLEK;;chr11:47400078..47400106,-!p1@SPI1!2.36!226.93!SPI1;;chr12:54778471..54778528,-!p1@ZNF385A!2.12!129.64!ZNF385A;;chr16:85932760..85932775,+!p1@IRF8!2.02!103.54!IRF8;;chr1:25256756..25256774,-!p1@RUNX3!1.89!140.86!RUNX3;;chr14:75746722..75746777,+!p2@FOS!1.88!94.91!FOS;;chr19:45971246..45971265,+!p1@FOSB!1.85!1221.81!FOSB;;chr5:133451294..133451310,+!p2@TCF7!1.85!69.03!TCF7;;chr2:157189180..157189290,-!p1@NR4A2!1.83!330.04!NR4A2;;chr14:75745523..75745537,+!p1@FOS!1.81!7095.70!FOS;;chr19:54058073..54058088,+!p1@ZNF331!1.81!63.42!ZNF331;;chr2:192015701..192015743,-!p1@STAT4!1.79!81.76!STAT4;;chr19:54041669..54041697,+!p2@ZNF331!1.79!60.62!ZNF331;;chr11:47400062..47400077,-!p2@SPI1!1.74!53.93!SPI1;;chr6:91006518..91006570,-!p1@BACH2!1.68!105.05!BACH2;;chr7:50344289..50344323,+!p1@IKZF1!1.67!45.52!IKZF1;;chr7:50343634..50343717,+!p2@IKZF1!1.67!45.30!IKZF1;;chr11:47399947..47399961,-!p3@SPI1!1.67!45.30!SPI1;;chr3:63953435..63953499,+!p1@ATXN7!1.64!42.50!ATXN7;;chr20:39317868..39317884,-!p1@MAFB!1.63!471.55!MAFB;;chr9:102584262..102584276,+!p1@NR4A3!1.63!90.82!NR4A3;;chrX:106960285..106960299,-!p1@TSC22D3!1.61!1006.31!TSC22D3;;chr2:145277640..145277771,-!p1@ZEB2!1.61!501.97!ZEB2;;chr12:72056800..72056834,+!p1@THAP2!1.60!52.20!THAP2;;chr14:35872453..35872485,-!p2@NFKBIA!1.59!91.46!NFKBIA;;chr14:35873947..35873965,-!p1@NFKBIA!1.58!2209.56!NFKBIA;;chrX:106960180..106960197,-!p2@TSC22D3!1.58!134.82!TSC22D3;;chr14:35872962..35873025,-!p3@NFKBIA!1.57!87.80!NFKBIA;;chr11:47399996..47400014,-!p4@SPI1!1.53!33.00!SPI1;;chr8:123793988..123794016,+!p1@ZHX2!1.52!55.44!ZHX2;;chr3:71355163..71355209,-!p5@FOXP1!1.52!44.01!FOXP1;;chr14:35872926..35872951,-!p4@NFKBIA!1.51!43.36!NFKBIA;;chr9:117150254..117150271,-!p1@AKNA!1.50!82.40!AKNA;;chr4:109087445..109087463,-!p1@LEF1!1.50!30.85!LEF1;;chr12:54778351..54778378,-!p6@ZNF385A!1.49!29.55!ZNF385A;;chrX:106960221..106960236,-!p3@TSC22D3!1.48!78.95!TSC22D3;;chr6:391743..391759,+!p1@IRF4!1.48!29.34!IRF4;;chr7:115670804..115670825,-!p1@TFEC!1.48!29.12!TFEC;;chr5:133450365..133450444,+!p1@TCF7!1.47!126.41!TCF7;;chr20:50159198..50159299,-!p1@NFATC2!1.47!40.99!NFATC2;;chrY:21906594..21906622,-!p1@KDM5D!1.46!27.83!KDM5D;;chr2:145271342..145271377,-!p5@ZEB2!1.45!27.18!ZEB2;;chr17:38497662..38497713,+!p4@RARA!1.43!29.98!RARA;;chr2:70142232..70142251,+!p1@MXD1!1.42!139.35!MXD1;;chr2:231090433..231090469,+!p1@SP140!1.42!25.45!SP140;;chr3:71542615..71542644,-!p12@FOXP1!1.41!24.59!FOXP1;;chr3:39195075..39195088,-!p1@CSRNP1!1.39!141.94!CSRNP1;;chr3:18486354..18486377,-!p2@SATB1!1.39!29.55!SATB1;;chr3:101546827..101546847,+!p2@NFKBIZ!1.38!31.93!NFKBIZ;;chr6:106546808..106546833,+!p3@PRDM1!1.37!28.26!PRDM1;;chr10:8096631..8096660,+!p1@GATA3!1.37!27.18!GATA3;;chr19:16435625..16435682,+!p1@KLF2!1.36!671.95!KLF2;;chr2:61108695..61108753,+!p1@REL!1.36!146.90!REL;;chr19:12902289..12902307,+!p1@JUNB!1.34!4567.75!JUNB;;chr6:12011943..12012015,+!p2@HIVEP1!1.33!63.85!HIVEP1;;chr10:35484053..35484076,+!p1@CREM!1.33!50.05!CREM;;chr2:157189617..157189667,-!p4@NR4A2!1.33!20.49!NR4A2;;chr2:68592394..68592405,+!p2@PLEK!1.33!20.49!PLEK;;chr4:103422499..103422632,+!p1@NFKB1!1.32!401.23!NFKB1;;chr9:102584128..102584144,+!p3@NR4A3!1.32!37.75!NR4A3;;chr9:102584241..102584261,+!p4@NR4A3!1.32!30.63!NR4A3;;chr2:192015750..192015793,-!p2@STAT4!1.32!26.75!STAT4;;chrY:2803415..2803468,+!p1@ZFY!1.32!20.06!ZFY;;chr5:131826457..131826514,-!p1@IRF1!1.30!726.09!IRF1;;chr6:91006575..91006602,-!p2@BACH2!1.30!27.83!BACH2;;chr3:128212033..128212051,-!p1@GATA2!1.30!18.98!GATA2;;chr3:101568349..101568365,+!p1@NFKBIZ!1.29!931.67!NFKBIZ;;chr6:106534192..106534224,+!p1@PRDM1!1.29!51.99!PRDM1;;chr11:47400032..47400043,-!p5@SPI1!1.28!18.12!SPI1;;chr14:64971288..64971316,-!p2@ZBTB25!1.27!53.07!ZBTB25;;chr10:104154246..104154347,+!p3@NFKB2!1.25!100.52!NFKB2;;chr6:144385698..144385742,-!p2@PLAGL1!1.25!20.28!PLAGL1;;chr17:45810594..45810608,+!p1@TBX21!1.25!16.61!TBX21;;chr9:110252035..110252057,-!p1@KLF4!1.24!253.90!KLF4;;chr19:54041645..54041661,+!p5@ZNF331!1.24!16.39!ZNF331;;chr4:109090075..109090095,-!p2@LEF1!1.23!16.18!LEF1;;chrX:106960249..106960260,-!p5@TSC22D3!1.22!24.81!TSC22D3;;chr12:54694758..54694805,-!p1@NFE2!1.22!18.98!NFE2;;chr2:192015677..192015691,-!p3@STAT4!1.22!15.75!STAT4;;chr5:133451347..133451358,+!p3@TCF7!1.22!15.53!TCF7;;chr8:81397820..81397836,+!p2@ZBTB10!1.21!18.98!ZBTB10;;chr10:51572408..51572454,+!p3@NCOA4!1.20!86.50!NCOA4;;chr9:102584159..102584174,+!p2@NR4A3!1.20!26.53!NR4A3;;chr8:81397846..81397860,+!p3@ZBTB10!1.20!18.77!ZBTB10;;chr19:33793430..33793447,-!p1@CEBPA!1.19!61.26!CEBPA;;chr2:208394817..208394834,+!p3@CREB1!1.19!57.81!CREB1;;chr14:35872494..35872511,-!p5@NFKBIA!1.19!19.41!NFKBIA;;chr3:39195037..39195069,-!p2@CSRNP1!1.18!86.93!CSRNP1;;chr12:72056773..72056796,+!p3@THAP2!1.18!18.55!THAP2;;chr14:35872542..35872553,-!p10@NFKBIA!1.18!14.24!NFKBIA;;chr17:38020392..38020477,-!p1@IKZF3!1.18!14.02!IKZF3;;chr21:36421535..36421610,-!p2@RUNX1!1.17!48.75!RUNX1;;chr9:3525727..3525828,-!p2@RFX3!1.17!34.95!RFX3;;chr19:36391434..36391450,-!p1@NFKBID!1.17!27.18!NFKBID;;chr14:35872414..35872425,-!p7@NFKBIA!1.17!15.53!NFKBIA;;chr6:44233252..44233296,-!p1@NFKBIE!1.16!131.59!NFKBIE;;chr7:128577972..128578047,+!p1@IRF5!1.16!21.36!IRF5;;chr11:47400045..47400060,-!p6@SPI1!1.16!13.37!SPI1;;chr10:3827371..3827386,-!p2@KLF6!1.15!108.72!KLF6;;chr2:145275162..145275202,-!p2@ZEB2!1.15!77.23!ZEB2;;chr10:35416142..35416169,+!p3@CREM!1.15!34.73!CREM;;chr20:56195474..56195506,-!p1@ZBP1!1.15!13.16!ZBP1;;chr19:42636586..42636607,-!p1@POU2F2!1.14!35.16!POU2F2;;chr19:45250948..45250998,+!p3@BCL3!1.13!31.71!BCL3;;chr8:81397876..81397898,+!p5@ZBTB10!1.12!14.45!ZBTB10;;chr7:50344251..50344288,+!p3@IKZF1!1.12!12.30!IKZF1;;chr14:35874077..35874091,-!p8@NFKBIA!1.12!12.30!NFKBIA;;chr2:231090471..231090504,+!p2@SP140!1.12!12.30!SP140;;chr10:104154415..104154434,+!p5@NFKB2!1.12!12.08!NFKB2;;chr19:50922187..50922204,+!p1@SPIB!1.12!12.08!SPIB;;chr21:34442439..34442455,+!p1@OLIG1!1.12!12.08!OLIG1;;chr12:52445218..52445237,+!p1@NR4A1!1.11!150.35!NR4A1;;chr2:97202480..97202499,+!p1@ARID5A!1.11!118.86!ARID5A;;chr7:104654718..104654741,+!p3@MLL5!1.11!17.26!MLL5;;chr2:61108808..61108821,+!p3@REL!1.11!14.88!REL;;chr6:106534230..106534254,+!p2@PRDM1!1.10!29.12!PRDM1;;chr13:41593425..41593480,-!p1@ELF1!1.09!72.05!ELF1;;chr15:60884706..60884743,-!p1@RORA!1.09!58.46!RORA;;chr1:25256439..25256476,-!p3@RUNX3!1.09!11.43!RUNX3;;chr2:100759010..100759035,-!p1@AFF3!1.09!11.43!AFF3;;chr2:61108878..61108891,+!p5@REL!1.09!11.22!REL;;chr14:75746781..75746799,+!p6@FOS!1.09!11.22!FOS;;chr16:31885093..31885165,+!p1@ZNF267!1.08!167.39!ZNF267;;chr2:208031542..208031595,-!p2@KLF7!1.08!77.66!KLF7;;chr7:106809470..106809481,+!p2@HBP1!1.08!15.53!HBP1;;chr17:38497715..38497734,+!p8@RARA!1.08!11.00!RARA;;chr10:94449703..94449718,+!p1@HHEX!1.07!42.28!HHEX;;chr10:8096772..8096787,+!p2@GATA3!1.07!12.73!GATA3;;chr7:50343895..50343936,+!p5@IKZF1!1.07!10.79!IKZF1;;chr6:15246261..15246312,+!p1@JARID2!1.06!254.97!JARID2;;chr4:106068026..106068084,+!p1@TET2!1.06!94.48!TET2;;chr1:156470515..156470542,-!p2@MEF2D!1.06!54.79!MEF2D;;chr7:149470641..149470694,-!p1@ZNF467!1.06!47.46!ZNF467;;chr7:104654690..104654704,+!p2@MLL5!1.06!20.92!MLL5;;chr6:12009042..12009092,+!p6@HIVEP1!1.06!13.81!HIVEP1;;chr3:71542651..71542683,-!p22@FOXP1!1.06!10.35!FOXP1;;chr11:128563948..128564003,+!p1@FLI1!1.05!125.55!FLI1;;chr1:59249688..59249703,-!p3@JUN!1.05!61.48!JUN;;chr19:45252008..45252024,+!p2@BCL3!1.05!34.08!BCL3;;chr9:102584278..102584285,+!p5@NR4A3!1.05!10.14!NR4A3;;chr9:110250697..110250738,-!p2@KLF4!1.04!11.86!KLF4;;chr1:151030536..151030549,+!p8@MLLT11!1.04!9.92!MLLT11;;chr3:18487057..18487105,-!p4@SATB1!1.04!9.92!SATB1;;chr3:71542684..71542720,-!p18@FOXP1!1.04!9.92!FOXP1;;chr5:172483347..172483407,+!p1@C5orf41!1.03!74.85!CREBRF;;chr22:38597987..38598021,+!p2@MAFF!1.02!58.46!MAFF;;chr18:3448455..3448480,+!p5@TGIF1!1.02!17.47!TGIF1;;chr19:45972701..45972774,+!p2@FOSB!1.02!12.94!FOSB;;chrX:129244454..129244488,-!p1@ELF4!1.01!67.30!ELF4;;chr2:157198916..157198978,-!p2@NR4A2!1.01!33.22!NR4A2;;chr19:12721790..12721810,+!p2@ZNF791!1.01!26.10!ZNF791;;chr6:15246200..15246214,+!p2@JARID2!1.01!26.10!JARID2;;chr14:64970670..64970712,-!p3@ZBTB25!1.01!20.06!ZBTB25;;chr6:143266297..143266356,-!p1@HIVEP2!1.00!44.87!HIVEP2;;chr7:17338324..17338341,+!p3@AHR!1.00!30.85!AHR;;chr19:19729477..19729542,-!p1@PBX4!1.00!19.63!PBX4;;chr5:142782823..142782854,-!p3@NR3C1!1.00!12.94!NR3C1;;chr3:39195139..39195150,-!p3@CSRNP1!1.00!11.65!CSRNP1;;chr14:75747250..75747267,+!p5@FOS!1.00!9.06!FOS;;chr10:104155480..104155534,+!p2@NFKB2!0.99!58.24!NFKB2;;chr3:187463179..187463201,-!p2@BCL6!0.99!37.10!BCL6;;chr11:113930425..113930471,+!p1@ZBTB16!0.99!12.94!ZBTB16;;chr14:99738138..99738163,-!p1@BCL11B!0.99!8.84!BCL11B;;chr2:61108650..61108687,+!p2@REL!0.98!42.71!REL;;chrX:153305787..153305807,-!p3@MECP2!0.98!8.63!MECP2;;chr2:43453734..43453751,-!p1@ZFP36L2!0.97!907.08!ZFP36L2;;chr11:111249993..111250006,-!p1@POU2AF1!0.97!8.41!POU2AF1;;chr11:47399920..47399931,-!p7@SPI1!0.97!8.41!SPI1;;chr19:45504688..45504782,+!p1@RELB!0.96!50.26!RELB;;chr1:59249707..59249727,-!p1@JUN!0.95!339.32!JUN;;chr1:212782094..212782109,+!p1@ATF3!0.95!221.75!ATF3;;chr17:38498594..38498661,+!p2@RARA!0.95!27.18!RARA;;chrX:101186981..101187030,-!p1@ZMAT1!0.95!26.32!ZMAT1;;chr12:72056749..72056767,+!p6@THAP2!0.95!8.84!THAP2;;chr13:74707894..74707947,-!p6@KLF12!0.95!8.84!KLF12;;chr3:5020939..5020952,+!p2@BHLHE40!0.94!25.02!BHLHE40;;chr8:71316428..71316459,-!p2@NCOA2!0.94!13.16!NCOA2;;chr2:61108771..61108789,+!p4@REL!0.94!11.86!REL;;chr4:38665769..38665801,+!p2@KLF3!0.93!70.75!KLF3;;chr18:77155922..77155939,+!p1@NFATC1!0.93!21.14!NFATC1;;chr19:13213662..13213686,-!p1@LYL1!0.93!11.22!LYL1;;chr4:83822199..83822239,+!p2@THAP9!0.93!9.06!THAP9;;chr14:64971461..64971542,+!p1@ZBTB1!0.92!154.02!ZBTB1;;chr15:31619326..31619390,+!p2@KLF13!0.92!87.36!KLF13;;chr5:88178983..88179012,-!p1@MEF2C!0.92!59.32!MEF2C;;ch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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000222;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000738;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000842;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000988;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002193;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002390 | |||
|ffid_belonging_in_development=CL:0000134 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 43: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|top_motifs= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Peripheral%2520Blood%2520Mononuclear%2520Cells%252c%2520donor2.CNhs11958.11312-117C7.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Peripheral%2520Blood%2520Mononuclear%2520Cells%252c%2520donor2.CNhs11958.11312-117C7.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Peripheral%2520Blood%2520Mononuclear%2520Cells%252c%2520donor2.CNhs11958.11312-117C7.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Peripheral%2520Blood%2520Mononuclear%2520Cells%252c%2520donor2.CNhs11958.11312-117C7.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Peripheral%2520Blood%2520Mononuclear%2520Cells%252c%2520donor2.CNhs11958.11312-117C7.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11312-117C7 | |||
|is_a=EFO:0002091;;FF:0000135 | |||
|is_obsolete= | |||
|library_id=CNhs11958 | |||
|library_id_phase_based=2:CNhs11958 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11312 | |||
|microRNAs_nonnovel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer/#/human#srna;sample;SRhi10005.CGTACG.11312 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11312 | |||
|microRNAs_novel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer_novel/#/human#srna;sample;SRhi10005.CGTACG.11312 | |||
|name=Peripheral Blood Mononuclear Cells, donor2 | |||
|namespace=FANTOM5 | |||
|part_of= | |||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs11958,LSID836,release011,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=SRhi10005,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0.499294116888918,0.135089736106763,0.102846826419324,0,0.0848314897427103,0.0848314897427103,0.275162192054403,0.216731200128301,-0.0606309320652131,0.731362191520053,0,0,0,0,0,0,0,0,0,0,0.270179472213526,0,0,0.282157211792361,0,0,0,0,0.0848314897427103,0.370600297524027,0,0.0424157448713552,0.493969937339835,0,0,0,0.0848314897427103,0,0.120300559872549,0,0.155769630002388,0,0.0848314897427103,0,0,0.365723945679736,0.360647404506958,0.0848314897427103,0,0,0,0,0.155769630002388,0,0.110874714993928,0,0,0,0.270179472213526,0,0,0.0848314897427103,0.371565832549479,0,0.669050960163739,0.172835845000429,0,0.714197422619102,0,0,0,0,0.399673618657105,0,0,0,1.18900862983481,0,0,0.435480222140789,0,0,0,0.0848314897427103,0.0424157448713552,0,0.0848314897427103,0.0198992782837267,0,0,-0.091785497138503,0,0,0,0.190157280286074,0.302611921928495,0,0,0.371362495646539,0,0.456886120522711,0.614101807831109,0,0,0,0,0,0.263998913410065,0.216731200128301,0,0,0,0,0,0.077884815001194,0.0308958338478152,0,0,0,-0.096373593922461,0.468558193792084,0,0,0.26149466399249,0.400549640843151,0,0,0.275173204578886,0,0,0 | |||
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| |||
|rna_box=117 | |||
|rna_catalog_number=3H100-10-10 | |||
|rna_concentration=1.051 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-TRIzol-isopropanol-v1.0 | |||
|rna_lot_number=PBMC722 | |||
|rna_od260/230= | |||
|rna_od260/280= | |||
|rna_position=C7 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=117C7 | |||
|rna_weight_ug=10 | |||
|rnaseq_library_id=SRhi10005.CGTACG | |||
|sample_age=65 | |||
|sample_category=primary cells | |||
|sample_cell_catalog=N/A | |||
|sample_cell_line= | |||
|sample_cell_lot=N/A | |||
|sample_cell_type=mononuclear cell | |||
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest) | |||
|sample_company=3HBiomedical | |||
|sample_description= | |||
|sample_dev_stage=65 years old adult | |||
|sample_disease= | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=C | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;4.1839754847618e-227!GO:0043227;membrane-bound organelle;7.16257637921714e-154!GO:0043231;intracellular membrane-bound organelle;1.19784999329418e-153!GO:0043226;organelle;8.85812285195386e-143!GO:0043229;intracellular organelle;4.10423335468939e-142!GO:0005737;cytoplasm;8.92036560284031e-127!GO:0044422;organelle part;4.55802732693617e-82!GO:0043170;macromolecule metabolic process;2.46765354326543e-81!GO:0044446;intracellular organelle part;1.55877025259463e-80!GO:0005634;nucleus;2.59744841132131e-80!GO:0044237;cellular metabolic process;3.81532508051672e-80!GO:0044238;primary metabolic process;1.40517878472097e-78!GO:0044444;cytoplasmic part;2.28568955616575e-78!GO:0005515;protein binding;2.22764484363901e-71!GO:0032991;macromolecular complex;3.1416104188895e-69!GO:0044428;nuclear part;8.45797602920912e-63!GO:0003723;RNA binding;2.51504840095358e-62!GO:0030529;ribonucleoprotein complex;2.86583856761867e-55!GO:0043283;biopolymer metabolic process;2.55883018821341e-54!GO:0043233;organelle lumen;5.00972840655433e-49!GO:0031974;membrane-enclosed lumen;5.00972840655433e-49!GO:0010467;gene expression;7.00864904470699e-48!GO:0019538;protein metabolic process;3.04598171668364e-47!GO:0044267;cellular protein metabolic process;2.44380305131548e-44!GO:0033036;macromolecule localization;5.67104623343741e-44!GO:0044260;cellular macromolecule metabolic process;6.02169012949131e-44!GO:0015031;protein transport;8.19577085302228e-43!GO:0006412;translation;1.67164849358634e-42!GO:0045184;establishment of protein localization;1.42813127984739e-41!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.00729301658001e-40!GO:0008104;protein localization;1.47010814772103e-40!GO:0031981;nuclear lumen;8.90300869381693e-39!GO:0043234;protein complex;2.0346554444747e-36!GO:0016071;mRNA metabolic process;3.56245589734514e-36!GO:0006396;RNA processing;1.02951394605399e-35!GO:0005739;mitochondrion;9.87550144381006e-32!GO:0008380;RNA splicing;1.79699285919545e-31!GO:0005829;cytosol;1.79699285919545e-31!GO:0016043;cellular component organization and biogenesis;4.77419399958384e-31!GO:0006915;apoptosis;1.12739196347122e-30!GO:0031090;organelle membrane;1.25399930430863e-30!GO:0012501;programmed cell death;1.4443219393908e-30!GO:0009059;macromolecule biosynthetic process;5.32410184515507e-30!GO:0006397;mRNA processing;1.74193694022423e-29!GO:0046907;intracellular transport;2.79223682024348e-29!GO:0005840;ribosome;4.49129352731606e-29!GO:0008219;cell death;6.06272389361027e-29!GO:0016265;death;6.06272389361027e-29!GO:0031967;organelle envelope;8.73916613288682e-29!GO:0031975;envelope;1.85433046742596e-28!GO:0003676;nucleic acid binding;2.01642999349709e-28!GO:0006886;intracellular protein transport;2.55486298717197e-28!GO:0065003;macromolecular complex assembly;5.70715836104085e-26!GO:0005654;nucleoplasm;6.08331027520853e-26!GO:0003735;structural constituent of ribosome;8.90109921368211e-26!GO:0016070;RNA metabolic process;3.79399188340048e-25!GO:0044249;cellular biosynthetic process;9.95194107437811e-25!GO:0033279;ribosomal subunit;9.95194107437811e-25!GO:0005681;spliceosome;7.04770762809121e-24!GO:0009058;biosynthetic process;7.62651538301287e-24!GO:0000166;nucleotide binding;1.01161205894956e-23!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.99762015790556e-23!GO:0044429;mitochondrial part;3.07619030933382e-23!GO:0051649;establishment of cellular localization;9.61537936766701e-23!GO:0022607;cellular component assembly;9.8985589354198e-23!GO:0051641;cellular localization;1.09663387515919e-22!GO:0042981;regulation of apoptosis;2.03171464093129e-21!GO:0044451;nucleoplasm part;2.23902335984436e-21!GO:0044445;cytosolic part;2.24324797946767e-21!GO:0050794;regulation of cellular process;2.5721930138135e-21!GO:0008134;transcription factor binding;2.91713043336934e-21!GO:0043067;regulation of programmed cell death;5.07902832302166e-21!GO:0043412;biopolymer modification;1.19867110869332e-20!GO:0006259;DNA metabolic process;3.4648675091953e-20!GO:0022613;ribonucleoprotein complex biogenesis and assembly;3.75482391057863e-19!GO:0006512;ubiquitin cycle;1.24186903578015e-18!GO:0006464;protein modification process;1.30865039905657e-18!GO:0043687;post-translational protein modification;2.64961288362792e-18!GO:0006996;organelle organization and biogenesis;3.22303548204768e-18!GO:0002376;immune system process;4.82265048393427e-18!GO:0044265;cellular macromolecule catabolic process;5.47715003119748e-18!GO:0032553;ribonucleotide binding;9.82154968379942e-18!GO:0032555;purine ribonucleotide binding;9.82154968379942e-18!GO:0006913;nucleocytoplasmic transport;3.43651474337077e-17!GO:0048523;negative regulation of cellular process;6.69280475974409e-17!GO:0005740;mitochondrial envelope;7.93175652748919e-17!GO:0051169;nuclear transport;8.28500037395771e-17!GO:0050789;regulation of biological process;1.10539509680573e-16!GO:0017076;purine nucleotide binding;1.13904304541896e-16!GO:0006605;protein targeting;1.50808315742063e-16!GO:0031966;mitochondrial membrane;1.68297531542206e-16!GO:0016462;pyrophosphatase activity;3.0092639800545e-16!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;3.429501187448e-16!GO:0016817;hydrolase activity, acting on acid anhydrides;4.72829926090646e-16!GO:0006119;oxidative phosphorylation;6.18046216238549e-16!GO:0017111;nucleoside-triphosphatase activity;7.32271302179318e-16!GO:0019941;modification-dependent protein catabolic process;7.35294882197884e-16!GO:0043632;modification-dependent macromolecule catabolic process;7.35294882197884e-16!GO:0019866;organelle inner membrane;8.23196690037555e-16!GO:0051603;proteolysis involved in cellular protein catabolic process;8.77625037746108e-16!GO:0006511;ubiquitin-dependent protein catabolic process;1.19125277291867e-15!GO:0044257;cellular protein catabolic process;1.92474844426972e-15!GO:0007243;protein kinase cascade;1.96987669362183e-15!GO:0022618;protein-RNA complex assembly;2.34644882097559e-15!GO:0016604;nuclear body;3.11407634618252e-15!GO:0006793;phosphorus metabolic process;4.27188693933134e-15!GO:0006796;phosphate metabolic process;4.27188693933134e-15!GO:0016192;vesicle-mediated transport;6.03047662217899e-15!GO:0016874;ligase activity;6.27357825218856e-15!GO:0043285;biopolymer catabolic process;8.41615690229967e-15!GO:0048519;negative regulation of biological process;1.00749978016434e-14!GO:0019222;regulation of metabolic process;5.03996353550855e-14!GO:0005524;ATP binding;5.84898451459244e-14!GO:0032559;adenyl ribonucleotide binding;1.32138588292166e-13!GO:0007242;intracellular signaling cascade;1.61962197926793e-13!GO:0009057;macromolecule catabolic process;1.83603190146042e-13!GO:0015935;small ribosomal subunit;1.84021094730106e-13!GO:0005743;mitochondrial inner membrane;2.00019341254137e-13!GO:0016310;phosphorylation;2.28118025199639e-13!GO:0016607;nuclear speck;2.92558748733779e-13!GO:0003712;transcription cofactor activity;3.33760378436144e-13!GO:0005730;nucleolus;5.85117108444612e-13!GO:0005635;nuclear envelope;6.19040754312456e-13!GO:0006955;immune response;6.22528651437508e-13!GO:0008135;translation factor activity, nucleic acid binding;7.2886710259999e-13!GO:0065007;biological regulation;7.72329794288522e-13!GO:0048770;pigment granule;8.6638382380102e-13!GO:0042470;melanosome;8.6638382380102e-13!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);8.6837171607691e-13!GO:0006366;transcription from RNA polymerase II promoter;9.08272488832489e-13!GO:0006325;establishment and/or maintenance of chromatin architecture;1.04186913787781e-12!GO:0007249;I-kappaB kinase/NF-kappaB cascade;1.60590584963698e-12!GO:0030554;adenyl nucleotide binding;1.60590584963698e-12!GO:0051246;regulation of protein metabolic process;2.09668873785782e-12!GO:0015934;large ribosomal subunit;2.34897962390734e-12!GO:0043069;negative regulation of programmed cell death;2.95162691752749e-12!GO:0043066;negative regulation of apoptosis;3.8042060941981e-12!GO:0044248;cellular catabolic process;4.2957686170923e-12!GO:0006323;DNA packaging;5.39567203861444e-12!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;6.33708833956312e-12!GO:0017038;protein import;7.27577517637978e-12!GO:0065009;regulation of a molecular function;8.27995841040731e-12!GO:0044455;mitochondrial membrane part;1.22287962447238e-11!GO:0012505;endomembrane system;2.29860449628309e-11!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);2.34342766050179e-11!GO:0006916;anti-apoptosis;2.43052387630195e-11!GO:0030163;protein catabolic process;2.69426962426381e-11!GO:0031323;regulation of cellular metabolic process;3.05512632457984e-11!GO:0007049;cell cycle;3.26736141198059e-11!GO:0005768;endosome;3.42397256592255e-11!GO:0031965;nuclear membrane;3.65689848195972e-11!GO:0000398;nuclear mRNA splicing, via spliceosome;7.0039272532679e-11!GO:0000375;RNA splicing, via transesterification reactions;7.0039272532679e-11!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;7.0039272532679e-11!GO:0051276;chromosome organization and biogenesis;7.41016942031338e-11!GO:0043228;non-membrane-bound organelle;7.60677153206267e-11!GO:0043232;intracellular non-membrane-bound organelle;7.60677153206267e-11!GO:0000502;proteasome complex (sensu Eukaryota);1.10888993815857e-10!GO:0008639;small protein conjugating enzyme activity;1.34400092441449e-10!GO:0005746;mitochondrial respiratory chain;1.44042314435472e-10!GO:0051170;nuclear import;1.81473615006433e-10!GO:0005794;Golgi apparatus;1.8423015938536e-10!GO:0031324;negative regulation of cellular metabolic process;2.07172121748515e-10!GO:0006606;protein import into nucleus;2.10128905664029e-10!GO:0004842;ubiquitin-protein ligase activity;2.14092387263165e-10!GO:0006457;protein folding;2.82387260412899e-10!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;3.00111375862487e-10!GO:0003743;translation initiation factor activity;3.85908386991173e-10!GO:0006413;translational initiation;4.76757326814614e-10!GO:0005773;vacuole;6.16486312263551e-10!GO:0006446;regulation of translational initiation;6.24049045392902e-10!GO:0044453;nuclear membrane part;8.31385270575902e-10!GO:0050136;NADH dehydrogenase (quinone) activity;1.01583504176586e-09!GO:0003954;NADH dehydrogenase activity;1.01583504176586e-09!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.01583504176586e-09!GO:0051726;regulation of cell cycle;1.04926999150628e-09!GO:0048522;positive regulation of cellular process;1.09195419426059e-09!GO:0016887;ATPase activity;1.1518026217114e-09!GO:0019787;small conjugating protein ligase activity;1.22910761200902e-09!GO:0016568;chromatin modification;1.3425171218735e-09!GO:0048193;Golgi vesicle transport;1.35345848830613e-09!GO:0006974;response to DNA damage stimulus;1.47540324519022e-09!GO:0000074;regulation of progression through cell cycle;1.62941337338025e-09!GO:0042623;ATPase activity, coupled;1.7489337896557e-09!GO:0043065;positive regulation of apoptosis;2.68966095608234e-09!GO:0045321;leukocyte activation;3.10149566786863e-09!GO:0010468;regulation of gene expression;3.30312229500763e-09!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;3.62907074639205e-09!GO:0009892;negative regulation of metabolic process;3.73480564551638e-09!GO:0016564;transcription repressor activity;3.85506742368886e-09!GO:0006417;regulation of translation;4.37978604972887e-09!GO:0043068;positive regulation of programmed cell death;4.7380521125751e-09!GO:0004386;helicase activity;5.02317112124698e-09!GO:0000323;lytic vacuole;5.72234986420836e-09!GO:0005764;lysosome;5.72234986420836e-09!GO:0050657;nucleic acid transport;8.40921531274315e-09!GO:0051236;establishment of RNA localization;8.40921531274315e-09!GO:0050658;RNA transport;8.40921531274315e-09!GO:0003713;transcription coactivator activity;1.07686525891899e-08!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.10264815501384e-08!GO:0031980;mitochondrial lumen;1.10983193848857e-08!GO:0005759;mitochondrial matrix;1.10983193848857e-08!GO:0006403;RNA localization;1.34080823045958e-08!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.53854358678014e-08!GO:0048518;positive regulation of biological process;1.5597472729995e-08!GO:0019829;cation-transporting ATPase activity;1.59604059548157e-08!GO:0006350;transcription;1.59898343344418e-08!GO:0019899;enzyme binding;1.68969827711824e-08!GO:0006917;induction of apoptosis;1.72075866504809e-08!GO:0008026;ATP-dependent helicase activity;1.99620193268289e-08!GO:0042775;organelle ATP synthesis coupled electron transport;2.00846548761354e-08!GO:0042773;ATP synthesis coupled electron transport;2.00846548761354e-08!GO:0016481;negative regulation of transcription;2.13832810976205e-08!GO:0016563;transcription activator activity;2.16013366218596e-08!GO:0046649;lymphocyte activation;2.24548054131117e-08!GO:0045786;negative regulation of progression through cell cycle;2.27205612781051e-08!GO:0006950;response to stress;2.498426611769e-08!GO:0005643;nuclear pore;2.89158449064583e-08!GO:0012502;induction of programmed cell death;3.07939569141394e-08!GO:0030964;NADH dehydrogenase complex (quinone);3.82790555944516e-08!GO:0045271;respiratory chain complex I;3.82790555944516e-08!GO:0005747;mitochondrial respiratory chain complex I;3.82790555944516e-08!GO:0009615;response to virus;5.15905233821713e-08!GO:0016772;transferase activity, transferring phosphorus-containing groups;5.84078725787174e-08!GO:0016787;hydrolase activity;6.37294830019702e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;6.72726567685648e-08!GO:0016879;ligase activity, forming carbon-nitrogen bonds;7.93622765924491e-08!GO:0006333;chromatin assembly or disassembly;7.95017653786872e-08!GO:0007264;small GTPase mediated signal transduction;8.19088244533364e-08!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;8.51183082097124e-08!GO:0009967;positive regulation of signal transduction;9.13793515278615e-08!GO:0051186;cofactor metabolic process;9.3618535385703e-08!GO:0031326;regulation of cellular biosynthetic process;9.69750019914314e-08!GO:0051082;unfolded protein binding;1.01579764756974e-07!GO:0016881;acid-amino acid ligase activity;1.05749001940091e-07!GO:0050790;regulation of catalytic activity;1.06673887375094e-07!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.14176904437676e-07!GO:0022402;cell cycle process;1.18901235916378e-07!GO:0009889;regulation of biosynthetic process;1.21897148931658e-07!GO:0001775;cell activation;1.80591228163894e-07!GO:0051028;mRNA transport;2.3790740217909e-07!GO:0065004;protein-DNA complex assembly;2.42841574227832e-07!GO:0042110;T cell activation;3.25249974893583e-07!GO:0005770;late endosome;3.6249104011132e-07!GO:0008565;protein transporter activity;3.78498958088742e-07!GO:0006461;protein complex assembly;4.08843513920502e-07!GO:0032446;protein modification by small protein conjugation;4.66397874951599e-07!GO:0009259;ribonucleotide metabolic process;4.94649297512807e-07!GO:0015986;ATP synthesis coupled proton transport;5.25515857655334e-07!GO:0015985;energy coupled proton transport, down electrochemical gradient;5.25515857655334e-07!GO:0009966;regulation of signal transduction;5.64083341712135e-07!GO:0009152;purine ribonucleotide biosynthetic process;5.81866778712396e-07!GO:0008047;enzyme activator activity;6.59196013217356e-07!GO:0006281;DNA repair;6.75631650728227e-07!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;7.18816250137858e-07!GO:0016567;protein ubiquitination;7.85851358874038e-07!GO:0009260;ribonucleotide biosynthetic process;7.85851358874038e-07!GO:0006164;purine nucleotide biosynthetic process;8.95872635970527e-07!GO:0009150;purine ribonucleotide metabolic process;9.38545158230355e-07!GO:0005783;endoplasmic reticulum;1.02497712535041e-06!GO:0009056;catabolic process;1.04458757495943e-06!GO:0004674;protein serine/threonine kinase activity;1.05166170177666e-06!GO:0060090;molecular adaptor activity;1.17247901093223e-06!GO:0015078;hydrogen ion transmembrane transporter activity;1.1724956254736e-06!GO:0006163;purine nucleotide metabolic process;1.27044688754722e-06!GO:0043566;structure-specific DNA binding;1.482917902814e-06!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.53854576932127e-06!GO:0044440;endosomal part;1.65599454384595e-06!GO:0010008;endosome membrane;1.65599454384595e-06!GO:0003697;single-stranded DNA binding;1.79455533596132e-06!GO:0046930;pore complex;1.88612104229891e-06!GO:0006357;regulation of transcription from RNA polymerase II promoter;1.9112383087281e-06!GO:0003924;GTPase activity;2.05246680224877e-06!GO:0045449;regulation of transcription;2.30195342181864e-06!GO:0016469;proton-transporting two-sector ATPase complex;2.53812142315259e-06!GO:0030695;GTPase regulator activity;2.55073507462851e-06!GO:0005525;GTP binding;2.55073507462851e-06!GO:0006732;coenzyme metabolic process;2.59477972228043e-06!GO:0005793;ER-Golgi intermediate compartment;3.12121663078295e-06!GO:0005694;chromosome;3.16097911917266e-06!GO:0008632;apoptotic program;3.17982637147906e-06!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;3.36465978577836e-06!GO:0000785;chromatin;4.23102860576211e-06!GO:0065002;intracellular protein transport across a membrane;4.25689807147922e-06!GO:0048468;cell development;4.75598360566479e-06!GO:0032774;RNA biosynthetic process;4.87012757907528e-06!GO:0006351;transcription, DNA-dependent;4.96545878570886e-06!GO:0030532;small nuclear ribonucleoprotein complex;5.07667565504856e-06!GO:0005839;proteasome core complex (sensu Eukaryota);5.5887911537151e-06!GO:0006754;ATP biosynthetic process;5.68519269752719e-06!GO:0006753;nucleoside phosphate metabolic process;5.68519269752719e-06!GO:0030097;hemopoiesis;6.13715081760618e-06!GO:0006401;RNA catabolic process;6.85374906915661e-06!GO:0003714;transcription corepressor activity;7.06198805600643e-06!GO:0016740;transferase activity;8.3524096219877e-06!GO:0009142;nucleoside triphosphate biosynthetic process;8.6812142477837e-06!GO:0009201;ribonucleoside triphosphate biosynthetic process;8.6812142477837e-06!GO:0009719;response to endogenous stimulus;9.08645480473307e-06!GO:0042254;ribosome biogenesis and assembly;1.03394432707129e-05!GO:0005057;receptor signaling protein activity;1.04599190393742e-05!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;1.13694611496733e-05!GO:0009145;purine nucleoside triphosphate biosynthetic process;1.13694611496733e-05!GO:0007265;Ras protein signal transduction;1.13694611496733e-05!GO:0016197;endosome transport;1.23064415396123e-05!GO:0009199;ribonucleoside triphosphate metabolic process;1.29995148517305e-05!GO:0002757;immune response-activating signal transduction;1.31443559399555e-05!GO:0046034;ATP metabolic process;1.33891617247278e-05!GO:0051168;nuclear export;1.4563247739752e-05!GO:0002764;immune response-regulating signal transduction;1.54549059268212e-05!GO:0048475;coated membrane;1.68512859781828e-05!GO:0030117;membrane coat;1.68512859781828e-05!GO:0009205;purine ribonucleoside triphosphate metabolic process;1.68512859781828e-05!GO:0009144;purine nucleoside triphosphate metabolic process;1.68512859781828e-05!GO:0009060;aerobic respiration;1.71674688384117e-05!GO:0045892;negative regulation of transcription, DNA-dependent;1.85644405774305e-05!GO:0044432;endoplasmic reticulum part;1.93376490949489e-05!GO:0001772;immunological synapse;2.01556239678943e-05!GO:0006402;mRNA catabolic process;2.24987612237241e-05!GO:0004298;threonine endopeptidase activity;2.31485004753562e-05!GO:0000151;ubiquitin ligase complex;2.31485004753562e-05!GO:0008270;zinc ion binding;2.42836822196339e-05!GO:0005774;vacuolar membrane;2.42836822196339e-05!GO:0030120;vesicle coat;2.61092132381991e-05!GO:0030662;coated vesicle membrane;2.61092132381991e-05!GO:0009141;nucleoside triphosphate metabolic process;2.73831244472652e-05!GO:0044427;chromosomal part;2.8407659086703e-05!GO:0003724;RNA helicase activity;3.13396415177249e-05!GO:0051336;regulation of hydrolase activity;3.27493593747667e-05!GO:0005070;SH3/SH2 adaptor activity;3.37643768873023e-05!GO:0045259;proton-transporting ATP synthase complex;3.43866657262385e-05!GO:0032561;guanyl ribonucleotide binding;3.50646612887272e-05!GO:0019001;guanyl nucleotide binding;3.50646612887272e-05!GO:0002429;immune response-activating cell surface receptor signaling pathway;3.8428850297342e-05!GO:0015077;monovalent inorganic cation transmembrane transporter activity;4.10075966058184e-05!GO:0031202;RNA splicing factor activity, transesterification mechanism;4.16251967043025e-05!GO:0031252;leading edge;4.35625418410933e-05!GO:0002768;immune response-regulating cell surface receptor signaling pathway;4.47898546989181e-05!GO:0002520;immune system development;4.81585029835398e-05!GO:0016044;membrane organization and biogenesis;4.8614910981884e-05!GO:0006888;ER to Golgi vesicle-mediated transport;5.01686841219162e-05!GO:0005096;GTPase activator activity;5.43435946302799e-05!GO:0000245;spliceosome assembly;5.87226909220484e-05!GO:0009893;positive regulation of metabolic process;6.14426701160967e-05!GO:0005761;mitochondrial ribosome;6.75001256004467e-05!GO:0000313;organellar ribosome;6.75001256004467e-05!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;6.75001256004467e-05!GO:0007050;cell cycle arrest;7.1434717623163e-05!GO:0006334;nucleosome assembly;7.69154766683676e-05!GO:0005083;small GTPase regulator activity;7.84064825006507e-05!GO:0046822;regulation of nucleocytoplasmic transport;8.17027784747062e-05!GO:0051090;regulation of transcription factor activity;8.19526191734624e-05!GO:0006355;regulation of transcription, DNA-dependent;8.27700472100139e-05!GO:0016301;kinase activity;8.41615776304728e-05!GO:0001816;cytokine production;8.52127850395688e-05!GO:0009607;response to biotic stimulus;9.04003651319548e-05!GO:0031497;chromatin assembly;9.16310491256078e-05!GO:0005765;lysosomal membrane;9.21391839910444e-05!GO:0016773;phosphotransferase activity, alcohol group as acceptor;9.55115881095254e-05!GO:0044437;vacuolar part;9.94324779120715e-05!GO:0009055;electron carrier activity;0.000107318729128398!GO:0051188;cofactor biosynthetic process;0.000108865411315722!GO:0031982;vesicle;0.000115140878373608!GO:0051251;positive regulation of lymphocyte activation;0.000125038988440094!GO:0006468;protein amino acid phosphorylation;0.000126452171691278!GO:0051223;regulation of protein transport;0.000155504142111313!GO:0005769;early endosome;0.000159260593938831!GO:0045333;cellular respiration;0.000165153903217025!GO:0048534;hemopoietic or lymphoid organ development;0.000184402519237261!GO:0031902;late endosome membrane;0.00020203217864951!GO:0042175;nuclear envelope-endoplasmic reticulum network;0.000214149089458204!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000216725472757603!GO:0006613;cotranslational protein targeting to membrane;0.000226650229854966!GO:0001819;positive regulation of cytokine production;0.000231482335242473!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;0.000251504775399372!GO:0003729;mRNA binding;0.000260274719844979!GO:0005789;endoplasmic reticulum membrane;0.000266308246968017!GO:0032940;secretion by cell;0.00027478756910174!GO:0005885;Arp2/3 protein complex;0.000276238282652493!GO:0009108;coenzyme biosynthetic process;0.000279320226937597!GO:0008186;RNA-dependent ATPase activity;0.000283477028132608!GO:0007005;mitochondrion organization and biogenesis;0.000284405627899465!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.000292323784043376!GO:0015399;primary active transmembrane transporter activity;0.000292323784043376!GO:0044431;Golgi apparatus part;0.000298144942653314!GO:0008234;cysteine-type peptidase activity;0.000327316800068363!GO:0005813;centrosome;0.000333501056677501!GO:0051338;regulation of transferase activity;0.000376775683092336!GO:0042101;T cell receptor complex;0.000388248250544226!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.000424375716192981!GO:0002521;leukocyte differentiation;0.000437963962984104!GO:0031410;cytoplasmic vesicle;0.000440340978265146!GO:0001817;regulation of cytokine production;0.000452073110976065!GO:0006752;group transfer coenzyme metabolic process;0.000452073110976065!GO:0022415;viral reproductive process;0.000455097191428815!GO:0045941;positive regulation of transcription;0.000459491317276989!GO:0006399;tRNA metabolic process;0.000466455603142729!GO:0016072;rRNA metabolic process;0.000482664367288441!GO:0043623;cellular protein complex assembly;0.000482893503371545!GO:0006099;tricarboxylic acid cycle;0.000482893503371545!GO:0046356;acetyl-CoA catabolic process;0.000482893503371545!GO:0031988;membrane-bound vesicle;0.000491241883155001!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000524399229990289!GO:0006919;caspase activation;0.000530637168686346!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;0.000535824476578509!GO:0004812;aminoacyl-tRNA ligase activity;0.000535824476578509!GO:0016875;ligase activity, forming carbon-oxygen bonds;0.000535824476578509!GO:0051427;hormone receptor binding;0.00054801736785538!GO:0006364;rRNA processing;0.000552991386721226!GO:0043549;regulation of kinase activity;0.000598568657134481!GO:0050851;antigen receptor-mediated signaling pathway;0.000605670019736941!GO:0018193;peptidyl-amino acid modification;0.000627238514115153!GO:0006260;DNA replication;0.000643747854368983!GO:0016363;nuclear matrix;0.000655362629425902!GO:0033157;regulation of intracellular protein transport;0.000656393294746525!GO:0042306;regulation of protein import into nucleus;0.000656393294746525!GO:0031325;positive regulation of cellular metabolic process;0.000679442631655189!GO:0043281;regulation of caspase activity;0.000711344100988196!GO:0046914;transition metal ion binding;0.000737336823810486!GO:0008654;phospholipid biosynthetic process;0.000795309253601122!GO:0005798;Golgi-associated vesicle;0.000800602961134589!GO:0004004;ATP-dependent RNA helicase activity;0.000828731060915564!GO:0030099;myeloid cell differentiation;0.000843678470415621!GO:0016779;nucleotidyltransferase activity;0.00085999065719443!GO:0006607;NLS-bearing substrate import into nucleus;0.000865111872594542!GO:0005667;transcription factor complex;0.000906158405984967!GO:0043038;amino acid activation;0.000932775880760854!GO:0006418;tRNA aminoacylation for protein translation;0.000932775880760854!GO:0043039;tRNA aminoacylation;0.000932775880760854!GO:0043280;positive regulation of caspase activity;0.00094206226233785!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000953454105612077!GO:0035257;nuclear hormone receptor binding;0.000968533304650427!GO:0045637;regulation of myeloid cell differentiation;0.00108585271115405!GO:0046983;protein dimerization activity;0.00109007047874207!GO:0005637;nuclear inner membrane;0.00113695928107656!GO:0016023;cytoplasmic membrane-bound vesicle;0.00114394685809955!GO:0045859;regulation of protein kinase activity;0.0012164883111698!GO:0006084;acetyl-CoA metabolic process;0.00125091287406217!GO:0006611;protein export from nucleus;0.00125945038524021!GO:0051187;cofactor catabolic process;0.0013339630095912!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00135145846784108!GO:0043492;ATPase activity, coupled to movement of substances;0.00137725430425037!GO:0001726;ruffle;0.00140697357237717!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.00149478024434697!GO:0005815;microtubule organizing center;0.00151089422760103!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00151362370658281!GO:0019221;cytokine and chemokine mediated signaling pathway;0.00152856966430694!GO:0051092;activation of NF-kappaB transcription factor;0.00159654894879655!GO:0030217;T cell differentiation;0.00159834226459095!GO:0045045;secretory pathway;0.00166691027875979!GO:0042113;B cell activation;0.00167995274776961!GO:0045893;positive regulation of transcription, DNA-dependent;0.001713166346201!GO:0000278;mitotic cell cycle;0.00172680033279545!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;0.00181534191337721!GO:0042990;regulation of transcription factor import into nucleus;0.00189919198043348!GO:0042991;transcription factor import into nucleus;0.00189919198043348!GO:0004715;non-membrane spanning protein tyrosine kinase activity;0.00195616537029488!GO:0048471;perinuclear region of cytoplasm;0.00205922533599823!GO:0030098;lymphocyte differentiation;0.00205922533599823!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00207467046930351!GO:0003690;double-stranded DNA binding;0.0021318740785117!GO:0043087;regulation of GTPase activity;0.0021318740785117!GO:0009117;nucleotide metabolic process;0.00217333592384347!GO:0019904;protein domain specific binding;0.00217493958371972!GO:0022890;inorganic cation transmembrane transporter activity;0.00228050165692558!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.00246383246775915!GO:0050865;regulation of cell activation;0.00248050021316012!GO:0050870;positive regulation of T cell activation;0.00252216761082449!GO:0002274;myeloid leukocyte activation;0.00255119710789837!GO:0009109;coenzyme catabolic process;0.00278907821679047!GO:0042802;identical protein binding;0.00282486443789744!GO:0043433;negative regulation of transcription factor activity;0.00287144073987883!GO:0006897;endocytosis;0.00294992147075766!GO:0010324;membrane invagination;0.00294992147075766!GO:0005741;mitochondrial outer membrane;0.00298117376456961!GO:0006891;intra-Golgi vesicle-mediated transport;0.00306869331020878!GO:0051249;regulation of lymphocyte activation;0.00324751896108606!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00324751896108606!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00324751896108606!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00324751896108606!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00330134466982926!GO:0030258;lipid modification;0.00336339760916953!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00336339760916953!GO:0008624;induction of apoptosis by extracellular signals;0.00340775026058279!GO:0007034;vacuolar transport;0.00347497725836658!GO:0006612;protein targeting to membrane;0.00347808899557575!GO:0043021;ribonucleoprotein binding;0.00360877560840254!GO:0030658;transport vesicle membrane;0.00363994577048114!GO:0006818;hydrogen transport;0.00367507859217453!GO:0030384;phosphoinositide metabolic process;0.00374718424523673!GO:0051049;regulation of transport;0.00375285824925762!GO:0045058;T cell selection;0.00395717974015915!GO:0051707;response to other organism;0.0039663156617728!GO:0003725;double-stranded RNA binding;0.004031060123796!GO:0006650;glycerophospholipid metabolic process;0.00404821965327434!GO:0015992;proton transport;0.00417972107474571!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00419300785053396!GO:0050871;positive regulation of B cell activation;0.00440785416121822!GO:0002252;immune effector process;0.00456039389866205!GO:0006352;transcription initiation;0.00459527743670659!GO:0003677;DNA binding;0.00467658663420877!GO:0030218;erythrocyte differentiation;0.00467665128279071!GO:0051252;regulation of RNA metabolic process;0.00489629688716553!GO:0051091;positive regulation of transcription factor activity;0.00496155442600678!GO:0019220;regulation of phosphate metabolic process;0.00500643305182869!GO:0051174;regulation of phosphorus metabolic process;0.00500643305182869!GO:0033116;ER-Golgi intermediate compartment membrane;0.00500643305182869!GO:0004722;protein serine/threonine phosphatase activity;0.00503881053246605!GO:0000139;Golgi membrane;0.00506871639234986!GO:0005099;Ras GTPase activator activity;0.00535494146036354!GO:0030118;clathrin coat;0.00542637122017737!GO:0006310;DNA recombination;0.00552565927904771!GO:0008287;protein serine/threonine phosphatase complex;0.00570024607160039!GO:0016584;nucleosome positioning;0.0057426220937545!GO:0016251;general RNA polymerase II transcription factor activity;0.00574293388870654!GO:0019867;outer membrane;0.00576534337478146!GO:0006414;translational elongation;0.00576534337478146!GO:0002440;production of molecular mediator of immune response;0.00581289774765491!GO:0017091;AU-rich element binding;0.00589613325944737!GO:0050779;RNA destabilization;0.00589613325944737!GO:0000289;poly(A) tail shortening;0.00589613325944737!GO:0015631;tubulin binding;0.0059118401344187!GO:0008637;apoptotic mitochondrial changes;0.00591218522967119!GO:0031625;ubiquitin protein ligase binding;0.00606974733172713!GO:0030036;actin cytoskeleton organization and biogenesis;0.00616402820772315!GO:0016791;phosphoric monoester hydrolase activity;0.00626656348957971!GO:0031968;organelle outer membrane;0.00626656348957971!GO:0019901;protein kinase binding;0.00628452707428879!GO:0042613;MHC class II protein complex;0.00649140440727675!GO:0051098;regulation of binding;0.006620512818565!GO:0032318;regulation of Ras GTPase activity;0.00673443474646594!GO:0032386;regulation of intracellular transport;0.00686832805842392!GO:0051345;positive regulation of hydrolase activity;0.00699466064202518!GO:0043300;regulation of leukocyte degranulation;0.00736517023504253!GO:0045646;regulation of erythrocyte differentiation;0.00741223429130882!GO:0008629;induction of apoptosis by intracellular signals;0.00741223429130882!GO:0007041;lysosomal transport;0.00741597362797428!GO:0008139;nuclear localization sequence binding;0.00758116184575174!GO:0016311;dephosphorylation;0.00767411673437046!GO:0006672;ceramide metabolic process;0.00772626135561444!GO:0043488;regulation of mRNA stability;0.00781391244104595!GO:0043487;regulation of RNA stability;0.00781391244104595!GO:0019882;antigen processing and presentation;0.00808013303361525!GO:0019843;rRNA binding;0.00846464367021343!GO:0045792;negative regulation of cell size;0.00846464367021343!GO:0050900;leukocyte migration;0.0084991654808389!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00853775195208764!GO:0004672;protein kinase activity;0.00853817297028662!GO:0046519;sphingoid metabolic process;0.00906090147547793!GO:0006405;RNA export from nucleus;0.0090791027480849!GO:0004185;serine carboxypeptidase activity;0.00947535842568109!GO:0045576;mast cell activation;0.00948219068921021!GO:0030041;actin filament polymerization;0.00948219068921021!GO:0030660;Golgi-associated vesicle membrane;0.0098137138229909!GO:0002822;regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains.;0.0098137138229909!GO:0002819;regulation of adaptive immune response;0.0098137138229909!GO:0033673;negative regulation of kinase activity;0.0098137138229909!GO:0006469;negative regulation of protein kinase activity;0.0098137138229909!GO:0007259;JAK-STAT cascade;0.0098137138229909!GO:0030308;negative regulation of cell growth;0.0098137138229909!GO:0003746;translation elongation factor activity;0.00998520719789048!GO:0051789;response to protein stimulus;0.0101238269581555!GO:0006986;response to unfolded protein;0.0101238269581555!GO:0043085;positive regulation of catalytic activity;0.0102798083744387!GO:0005684;U2-dependent spliceosome;0.0104466719386434!GO:0031072;heat shock protein binding;0.0105684513224443!GO:0046966;thyroid hormone receptor binding;0.0106224415051889!GO:0043299;leukocyte degranulation;0.0108995240752144!GO:0000209;protein polyubiquitination;0.0110658010879381!GO:0050863;regulation of T cell activation;0.0112351840752537!GO:0031901;early endosome membrane;0.0113577942266364!GO:0002443;leukocyte mediated immunity;0.0114993333358493!GO:0019210;kinase inhibitor activity;0.0115515531394873!GO:0007040;lysosome organization and biogenesis;0.0121087122864905!GO:0005669;transcription factor TFIID complex;0.0122467421650203!GO:0006643;membrane lipid metabolic process;0.0124485673819717!GO:0019079;viral genome replication;0.0126510346929121!GO:0045926;negative regulation of growth;0.0130898757489245!GO:0006261;DNA-dependent DNA replication;0.0131377967451296!GO:0005048;signal sequence binding;0.013495165955908!GO:0051235;maintenance of localization;0.0134992176394374!GO:0004860;protein kinase inhibitor activity;0.0135074576899224!GO:0051348;negative regulation of transferase activity;0.0135819538130023!GO:0051059;NF-kappaB binding;0.0137571777820673!GO:0019058;viral infectious cycle;0.0138806894374325!GO:0008017;microtubule binding;0.0138806894374325!GO:0046578;regulation of Ras protein signal transduction;0.0138896430496966!GO:0051329;interphase of mitotic cell cycle;0.0139253454476056!GO:0045603;positive regulation of endothelial cell differentiation;0.0142219162828249!GO:0030518;steroid hormone receptor signaling pathway;0.0142219162828249!GO:0001516;prostaglandin biosynthetic process;0.014330887976795!GO:0046457;prostanoid biosynthetic process;0.014330887976795!GO:0019783;small conjugating protein-specific protease activity;0.0145809082440072!GO:0004177;aminopeptidase activity;0.0147927663268132!GO:0048487;beta-tubulin binding;0.0147927663268132!GO:0051051;negative regulation of transport;0.0147927663268132!GO:0030674;protein binding, bridging;0.0151709641079489!GO:0000118;histone deacetylase complex;0.0153635531374064!GO:0004197;cysteine-type endopeptidase activity;0.0159227086343978!GO:0000165;MAPKKK cascade;0.016016259664061!GO:0043621;protein self-association;0.0162442821710229!GO:0046467;membrane lipid biosynthetic process;0.016615982395957!GO:0015923;mannosidase activity;0.0166320009305613!GO:0019900;kinase binding;0.0166878003114584!GO:0031098;stress-activated protein kinase signaling pathway;0.0168174886482712!GO:0006376;mRNA splice site selection;0.0169595778883337!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0169595778883337!GO:0048500;signal recognition particle;0.0171080839928622!GO:0050811;GABA receptor binding;0.0171080839928622!GO:0045746;negative regulation of Notch signaling pathway;0.0174988812092885!GO:0019883;antigen processing and presentation of endogenous antigen;0.0175223398366872!GO:0002467;germinal center formation;0.0177069012132705!GO:0042108;positive regulation of cytokine biosynthetic process;0.0180062324347322!GO:0002444;myeloid leukocyte mediated immunity;0.0181940749509669!GO:0016505;apoptotic protease activator activity;0.018531849241869!GO:0003711;transcription elongation regulator activity;0.0188212616663281!GO:0004843;ubiquitin-specific protease activity;0.0191560632469791!GO:0002250;adaptive immune response;0.0193159886564953!GO:0002460;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.0193159886564953!GO:0000786;nucleosome;0.0194946775281638!GO:0046474;glycerophospholipid biosynthetic process;0.0195402412382422!GO:0051325;interphase;0.0195424214835339!GO:0002682;regulation of immune system process;0.0195424214835339!GO:0000082;G1/S transition of mitotic cell cycle;0.0202762109435767!GO:0006338;chromatin remodeling;0.0202762109435767!GO:0033367;protein localization in mast cell secretory granule;0.0202762109435767!GO:0033365;protein localization in organelle;0.0202762109435767!GO:0033371;T cell secretory granule organization and biogenesis;0.0202762109435767!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.0202762109435767!GO:0033375;protease localization in T cell secretory granule;0.0202762109435767!GO:0042629;mast cell granule;0.0202762109435767!GO:0033377;maintenance of protein localization in T cell secretory granule;0.0202762109435767!GO:0033364;mast cell secretory granule organization and biogenesis;0.0202762109435767!GO:0033380;granzyme B localization in T cell secretory granule;0.0202762109435767!GO:0033379;maintenance of protease localization in T cell secretory granule;0.0202762109435767!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.0202762109435767!GO:0033368;protease localization in mast cell secretory granule;0.0202762109435767!GO:0033366;protein localization in secretory granule;0.0202762109435767!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.0202762109435767!GO:0033374;protein localization in T cell secretory granule;0.0202762109435767!GO:0032763;regulation of mast cell cytokine production;0.0206051902346349!GO:0032762;mast cell cytokine production;0.0206051902346349!GO:0006984;ER-nuclear signaling pathway;0.0208117183610374!GO:0015630;microtubule cytoskeleton;0.0208502146847474!GO:0045069;regulation of viral genome replication;0.0212644303609528!GO:0046489;phosphoinositide biosynthetic process;0.0213180316564322!GO:0043304;regulation of mast cell degranulation;0.0213516104549651!GO:0004428;inositol or phosphatidylinositol kinase activity;0.0215619102356708!GO:0016585;chromatin remodeling complex;0.0217974436937786!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0220207793018889!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0220207793018889!GO:0030867;rough endoplasmic reticulum membrane;0.0226283122635664!GO:0051056;regulation of small GTPase mediated signal transduction;0.0227164956954613!GO:0051050;positive regulation of transport;0.0227764760221968!GO:0030127;COPII vesicle coat;0.0232170310789097!GO:0012507;ER to Golgi transport vesicle membrane;0.0232170310789097!GO:0006968;cellular defense response;0.0234348833732943!GO:0007033;vacuole organization and biogenesis;0.0237265108775399!GO:0005521;lamin binding;0.0244378346422264!GO:0001836;release of cytochrome c from mitochondria;0.0247041718925608!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0251700384960698!GO:0043681;protein import into mitochondrion;0.0252425696095861!GO:0017166;vinculin binding;0.0252690812226902!GO:0042325;regulation of phosphorylation;0.0253279714335007!GO:0006595;polyamine metabolic process;0.0253682128258265!GO:0003702;RNA polymerase II transcription factor activity;0.0254322962650577!GO:0047485;protein N-terminus binding;0.0259259361740793!GO:0050864;regulation of B cell activation;0.02619469879553!GO:0030176;integral to endoplasmic reticulum membrane;0.0262608265310308!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.026592028368714!GO:0000287;magnesium ion binding;0.026592028368714!GO:0009165;nucleotide biosynthetic process;0.0266449066226597!GO:0006354;RNA elongation;0.0270145540423036!GO:0030119;AP-type membrane coat adaptor complex;0.0275429434015545!GO:0043022;ribosome binding;0.0275863607690891!GO:0046854;phosphoinositide phosphorylation;0.0279240148173493!GO:0050857;positive regulation of antigen receptor-mediated signaling pathway;0.0285249715034085!GO:0006914;autophagy;0.0285444200960554!GO:0044262;cellular carbohydrate metabolic process;0.0288863481121137!GO:0002448;mast cell mediated immunity;0.0289907245647124!GO:0043303;mast cell degranulation;0.0289907245647124!GO:0007006;mitochondrial membrane organization and biogenesis;0.0292079900345491!GO:0045454;cell redox homeostasis;0.0294053778424676!GO:0030027;lamellipodium;0.0294627636977332!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0294627636977332!GO:0005762;mitochondrial large ribosomal subunit;0.0294627636977332!GO:0000315;organellar large ribosomal subunit;0.0294627636977332!GO:0007254;JNK cascade;0.029471571094348!GO:0042348;NF-kappaB import into nucleus;0.0299793274728493!GO:0042345;regulation of NF-kappaB import into nucleus;0.0299793274728493!GO:0000303;response to superoxide;0.0300957704677832!GO:0005869;dynactin complex;0.0301955731018796!GO:0005791;rough endoplasmic reticulum;0.0302504788410933!GO:0030134;ER to Golgi transport vesicle;0.0310100452837841!GO:0045309;protein phosphorylated amino acid binding;0.0311132758172422!GO:0004221;ubiquitin thiolesterase activity;0.0311665397292871!GO:0030521;androgen receptor signaling pathway;0.0320774543534611!GO:0016605;PML body;0.0322161983242364!GO:0043407;negative regulation of MAP kinase activity;0.0322161983242364!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0322546307080161!GO:0045047;protein targeting to ER;0.0322546307080161!GO:0008312;7S RNA binding;0.0322706026810186!GO:0030131;clathrin adaptor complex;0.0325173114007687!GO:0003682;chromatin binding;0.0326809523164751!GO:0042287;MHC protein binding;0.0329559985437446!GO:0045947;negative regulation of translational initiation;0.0334340425215806!GO:0030125;clathrin vesicle coat;0.0344616480778662!GO:0030665;clathrin coated vesicle membrane;0.0344616480778662!GO:0051052;regulation of DNA metabolic process;0.035047346556933!GO:0030029;actin filament-based process;0.0351476867916861!GO:0051101;regulation of DNA binding;0.0354081582538579!GO:0000059;protein import into nucleus, docking;0.0361619471523063!GO:0005062;hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity;0.036178756246773!GO:0030149;sphingolipid catabolic process;0.0363871479355451!GO:0030522;intracellular receptor-mediated signaling pathway;0.0369135863100931!GO:0050671;positive regulation of lymphocyte proliferation;0.0374468471508868!GO:0032946;positive regulation of mononuclear cell proliferation;0.0374468471508868!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0374510067492789!GO:0001667;ameboidal cell migration;0.0375935043882412!GO:0032027;myosin light chain binding;0.0375935043882412!GO:0006213;pyrimidine nucleoside metabolic process;0.0376759330298687!GO:0033239;negative regulation of amine metabolic process;0.038004675828049!GO:0045763;negative regulation of amino acid metabolic process;0.038004675828049!GO:0001933;negative regulation of protein amino acid phosphorylation;0.038004675828049!GO:0009299;mRNA transcription;0.0383760392312084!GO:0045113;regulation of integrin biosynthetic process;0.0383760392312084!GO:0045112;integrin biosynthetic process;0.0383760392312084!GO:0046834;lipid phosphorylation;0.0391127928031857!GO:0004218;cathepsin S activity;0.0392470691540533!GO:0006007;glucose catabolic process;0.0399510523301686!GO:0004721;phosphoprotein phosphatase activity;0.0405114618594688!GO:0050776;regulation of immune response;0.0405972210484298!GO:0009891;positive regulation of biosynthetic process;0.0407711132174137!GO:0002218;activation of innate immune response;0.0411873662318075!GO:0002758;innate immune response-activating signal transduction;0.0411873662318075!GO:0004527;exonuclease activity;0.0413140638038406!GO:0008656;caspase activator activity;0.0414212010610253!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.0417656969064272!GO:0000288;mRNA catabolic process, deadenylation-dependent decay;0.0419300690950189!GO:0043506;regulation of JNK activity;0.0419300690950189!GO:0050852;T cell receptor signaling pathway;0.0420433882416557!GO:0001784;phosphotyrosine binding;0.0422963026982354!GO:0046456;icosanoid biosynthetic process;0.0423257824286474!GO:0002237;response to molecule of bacterial origin;0.0429714433989661!GO:0000060;protein import into nucleus, translocation;0.0431459330774716!GO:0040029;regulation of gene expression, epigenetic;0.0433660354538044!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0435255622972151!GO:0051087;chaperone binding;0.0444138251630578!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.0451194629972633!GO:0005484;SNAP receptor activity;0.0456230431722852!GO:0030100;regulation of endocytosis;0.0458149292699707!GO:0051247;positive regulation of protein metabolic process;0.0459598578150434!GO:0048872;homeostasis of number of cells;0.0460407407599422!GO:0045185;maintenance of protein localization;0.0460407407599422!GO:0006470;protein amino acid dephosphorylation;0.0463018959463461!GO:0048002;antigen processing and presentation of peptide antigen;0.0463068909689769!GO:0032760;positive regulation of tumor necrosis factor production;0.0463692466389168!GO:0006302;double-strand break repair;0.0467573694149253!GO:0006644;phospholipid metabolic process;0.0468163665523099!GO:0016566;specific transcriptional repressor activity;0.0468163665523099!GO:0022411;cellular component disassembly;0.0474125009453036!GO:0045086;positive regulation of interleukin-2 biosynthetic process;0.0475244196694539!GO:0006383;transcription from RNA polymerase III promoter;0.0477101347410707!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0477301926007624!GO:0030132;clathrin coat of coated pit;0.0478284739135933!GO:0016788;hydrolase activity, acting on ester bonds;0.0478284739135933!GO:0008286;insulin receptor signaling pathway;0.0480071069562409!GO:0006516;glycoprotein catabolic process;0.0489985283726143!GO:0046839;phospholipid dephosphorylation;0.0491345277626263!GO:0050792;regulation of viral reproduction;0.0492370126015083!GO:0042992;negative regulation of transcription factor import into nucleus;0.0497380620359552!GO:0042308;negative regulation of protein import into nucleus;0.0497380620359552!GO:0008097;5S rRNA binding;0.0497380620359552!GO:0030833;regulation of actin filament polymerization;0.0498504032388759!GO:0006661;phosphatidylinositol biosynthetic process;0.0498634984056183 | |||
|sample_id=11312 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=blood | |||
|top_motifs=RUNX1..3:3.44021910671;ETS1,2:3.37024871142;PAX3,7:3.26353505301;NFKB1_REL_RELA:3.11810917673;SPI1:3.05998085384;ATF5_CREB3:3.04664930938;SPIB:2.95990958733;PAX2:2.930717661;DMAP1_NCOR{1,2}_SMARC:2.76845300942;ATF4:2.72940166107;CREB1:2.70375909855;FOX{D1,D2}:2.4827541483;FOXO1,3,4:2.37466477617;CEBPA,B_DDIT3:2.3370116932;NFIL3:2.19671549292;ELF1,2,4:2.12798683104;RXRA_VDR{dimer}:2.07982786769;FOXN1:2.07909124546;TGIF1:2.03636026601;BACH2:2.00869726209;BPTF:1.89107450028;FOS_FOS{B,L1}_JUN{B,D}:1.89089071045;JUN:1.86043128363;PITX1..3:1.85145196116;MAFB:1.81495267096;HMX1:1.80378511757;IRF1,2:1.78766222754;HIF1A:1.76698237528;RFX2..5_RFXANK_RFXAP:1.71457014925;NANOG{mouse}:1.70170748058;HLF:1.66803680778;FOXP1:1.61228118854;FOSL2:1.58298241647;NFATC1..3:1.56270948612;FOX{F1,F2,J1}:1.54167789009;NFE2:1.49534495746;FOXP3:1.45935031757;RORA:1.42021104915;T:1.41120382529;IRF7:1.34316249957;EP300:1.30093120498;ATF2:1.26564207501;ATF6:1.18659730415;STAT2,4,6:0.989994086398;SREBF1,2:0.955362139809;NFE2L1:0.933296742471;HMGA1,2:0.928948727679;NKX2-1,4:0.819216367352;NFE2L2:0.722428565332;IKZF2:0.675054493104;TLX2:0.642830020691;SMAD1..7,9:0.476961605262;ZBTB16:0.347738961105;TOPORS:0.248992048781;CDX1,2,4:0.238685993885;BREu{core}:0.210462292733;PAX8:0.209614417507;NKX3-1:0.164981558513;POU2F1..3:0.155520687925;EGR1..3:0.151919284108;SPZ1:0.123830394637;GATA4:0.0866364301964;GLI1..3:0.0801294148501;RBPJ:0.0426300311917;HOXA9_MEIS1:0.0219330748046;FOXD3:0.00574397006742;PAX6:0.0037326474389;MYFfamily:-0.0813955772401;RFX1:-0.102386293584;HBP1_HMGB_SSRP1_UBTF:-0.11538235627;NR5A1,2:-0.132965745809;SOX2:-0.201801579293;PPARG:-0.202471230278;RXR{A,B,G}:-0.245528056268;AHR_ARNT_ARNT2:-0.248496156775;TBX4,5:-0.257996236501;MYB:-0.258172755068;FOXL1:-0.288301315419;HES1:-0.305139230577;ALX4:-0.306208226372;NKX6-1,2:-0.31474751438;MEF2{A,B,C,D}:-0.32229118406;XBP1:-0.327846942146;TFAP4:-0.329311234494;POU5F1:-0.331549210037;GATA6:-0.342688677694;HSF1,2:-0.406853670828;TAL1_TCF{3,4,12}:-0.478274097956;FOX{I1,J2}:-0.496082597172;ZEB1:-0.506366364427;AIRE:-0.515064609949;NANOG:-0.525825587693;STAT1,3:-0.55791815107;MZF1:-0.560877943856;TFCP2:-0.57030029231;SRF:-0.579391649558;ESR1:-0.608234958105;OCT4_SOX2{dimer}:-0.610167634714;PDX1:-0.62005680097;NR1H4:-0.630267154188;ESRRA:-0.643644761662;PATZ1:-0.668067139525;MTE{core}:-0.669314892067;NR6A1:-0.772924333338;GCM1,2:-0.781225850816;STAT5{A,B}:-0.7888336054;E2F1..5:-0.792628801286;ZFP161:-0.797646449177;HNF4A_NR2F1,2:-0.800706599133;PAX5:-0.81560851037;ZNF384:-0.853100983418;ZNF238:-0.862323210048;NHLH1,2:-0.864484068197;RREB1:-0.868752857633;MED-1{core}:-0.87961744248;TFAP2{A,C}:-0.889949383417;SOX5:-0.903879385985;SNAI1..3:-0.909037440384;MTF1:-0.914802627101;SP1:-0.950223774507;RXR{A,B,G}_{NR1H2,PPAR}dimers:-1.01668211947;PRDM1:-1.042597941;EN1,2:-1.04423520655;TFAP2B:-1.05441213327;PAX4:-1.06494192643;MYOD1:-1.08404246368;HOX{A5,B5}:-1.09771091982;REST:-1.10546857186;LEF1_TCF7_TCF7L1,2:-1.1161617214;DBP:-1.1315719251;HNF1A:-1.18683376928;ZNF148:-1.19849867765;ZNF423:-1.20989616917;NFIX:-1.25199117346;FOXA2:-1.28509088374;HIC1:-1.28612608858;PRRX1,2:-1.30164562514;NFY{A,B,C}:-1.31874463508;TFDP1:-1.32374275746;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-1.33284470934;MAZ:-1.34970352374;ELK1,4_GABP{A,B1}:-1.35015883587;FOXQ1:-1.35429335117;LMO2:-1.36108620747;VSX1,2:-1.42945358161;TBP:-1.43865056955;FOXM1:-1.44099169907;SOX{8,9,10}:-1.50595502912;EVI1:-1.52580460323;ZBTB6:-1.54837690025;IKZF1:-1.56236279998;AR:-1.58325868587;CUX2:-1.63953636732;NRF1:-1.66976596251;XCPE1{core}:-1.70902821802;EBF1:-1.71408692635;POU6F1:-1.77476427621;bHLH_family:-1.77765571696;GTF2I:-1.79393578629;ADNP_IRX_SIX_ZHX:-1.80085269705;PBX1:-1.81182191728;NR3C1:-1.81990220457;GZF1:-1.85206692129;GTF2A1,2:-1.87352901398;ZIC1..3:-1.91993986617;MYBL2:-1.94971503699;KLF4:-1.9498791639;TLX1..3_NFIC{dimer}:-1.95649486959;TEF:-1.96683575546;PAX1,9:-1.9704119109;TEAD1:-2.02240065551;CRX:-2.02753245573;TP53:-2.02902096338;UFEwm:-2.05050614285;NKX2-2,8:-2.05537015804;GFI1B:-2.05747316473;HOX{A6,A7,B6,B7}:-2.11302740137;YY1:-2.15884479243;ALX1:-2.18867786221;POU3F1..4:-2.22491979917;GFI1:-2.24889816681;ZNF143:-2.28819798694;NKX3-2:-2.343653296;LHX3,4:-2.34956176133;CDC5L:-2.35226568241;NKX2-3_NKX2-5:-2.40800299149;SOX17:-2.60046815588;ONECUT1,2:-2.66350627051;ARID5B:-2.74493577673;HAND1,2:-3.03987534493;HOX{A4,D4}:-3.05340710863;POU1F1:-3.06723133827 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11312-117C7;search_select_hide=table117:FF:11312-117C7 | |||
}} | }} |
Latest revision as of 16:32, 3 June 2020
Name: | Peripheral Blood Mononuclear Cells, donor2 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs11958 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4, 5, 6 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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RNA-Seq Accession numbers | ||||||||||||||||||||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11958
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11958
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.281 |
10 | 10 | 0.0134 |
100 | 100 | 0.992 |
101 | 101 | 0.635 |
102 | 102 | 0.932 |
103 | 103 | 0.721 |
104 | 104 | 0.574 |
105 | 105 | 0.108 |
106 | 106 | 0.00229 |
107 | 107 | 0.836 |
108 | 108 | 0.668 |
109 | 109 | 0.251 |
11 | 11 | 0.254 |
110 | 110 | 0.557 |
111 | 111 | 0.11 |
112 | 112 | 0.567 |
113 | 113 | 0.12 |
114 | 114 | 0.133 |
115 | 115 | 0.28 |
116 | 116 | 0.784 |
117 | 117 | 0.00966 |
118 | 118 | 0.153 |
119 | 119 | 0.677 |
12 | 12 | 0.295 |
120 | 120 | 0.602 |
121 | 121 | 0.669 |
122 | 122 | 0.51 |
123 | 123 | 4.80821e-4 |
124 | 124 | 0.929 |
125 | 125 | 0.427 |
126 | 126 | 0.328 |
127 | 127 | 0.793 |
128 | 128 | 0.0893 |
129 | 129 | 0.823 |
13 | 13 | 0.272 |
130 | 130 | 0.228 |
131 | 131 | 0.694 |
132 | 132 | 0.0918 |
133 | 133 | 0.769 |
134 | 134 | 0.839 |
135 | 135 | 0.533 |
136 | 136 | 0.999 |
137 | 137 | 0.00179 |
138 | 138 | 0.178 |
139 | 139 | 0.0229 |
14 | 14 | 0.32 |
140 | 140 | 0.499 |
141 | 141 | 0.368 |
142 | 142 | 0.758 |
143 | 143 | 0.0105 |
144 | 144 | 0.59 |
145 | 145 | 0.655 |
146 | 146 | 0.607 |
147 | 147 | 0.196 |
148 | 148 | 0.0648 |
149 | 149 | 0.818 |
15 | 15 | 0.116 |
150 | 150 | 0.768 |
151 | 151 | 0.15 |
152 | 152 | 0.382 |
153 | 153 | 0.887 |
154 | 154 | 0.357 |
155 | 155 | 0.314 |
156 | 156 | 0.829 |
157 | 157 | 0.808 |
158 | 158 | 0.0673 |
159 | 159 | 0.0421 |
16 | 16 | 0.823 |
160 | 160 | 0.965 |
161 | 161 | 0.58 |
162 | 162 | 0.0933 |
163 | 163 | 0.624 |
164 | 164 | 0.0555 |
165 | 165 | 0.273 |
166 | 166 | 0.777 |
167 | 167 | 0.276 |
168 | 168 | 0.155 |
169 | 169 | 0.109 |
17 | 17 | 0.452 |
18 | 18 | 0.331 |
19 | 19 | 0.995 |
2 | 2 | 0.612 |
20 | 20 | 0.378 |
21 | 21 | 0.768 |
22 | 22 | 0.617 |
23 | 23 | 0.119 |
24 | 24 | 0.814 |
25 | 25 | 0.192 |
26 | 26 | 0.185 |
27 | 27 | 0.972 |
28 | 28 | 0.388 |
29 | 29 | 0.0907 |
3 | 3 | 0.233 |
30 | 30 | 0.191 |
31 | 31 | 0.969 |
32 | 32 | 0.102 |
33 | 33 | 0.253 |
34 | 34 | 0.815 |
35 | 35 | 0.107 |
36 | 36 | 0.124 |
37 | 37 | 0.127 |
38 | 38 | 0.585 |
39 | 39 | 0.988 |
4 | 4 | 0.832 |
40 | 40 | 0.37 |
41 | 41 | 0.0135 |
42 | 42 | 0.432 |
43 | 43 | 0.0459 |
44 | 44 | 0.605 |
45 | 45 | 0.888 |
46 | 46 | 0.306 |
47 | 47 | 0.647 |
48 | 48 | 0.577 |
49 | 49 | 0.0823 |
5 | 5 | 0.216 |
50 | 50 | 0.792 |
51 | 51 | 0.505 |
52 | 52 | 0.567 |
53 | 53 | 0.138 |
54 | 54 | 0.553 |
55 | 55 | 0.911 |
56 | 56 | 0.803 |
57 | 57 | 0.951 |
58 | 58 | 0.107 |
59 | 59 | 0.466 |
6 | 6 | 0.927 |
60 | 60 | 0.095 |
61 | 61 | 0.254 |
62 | 62 | 0.0695 |
63 | 63 | 0.78 |
64 | 64 | 0.397 |
65 | 65 | 0.363 |
66 | 66 | 0.0396 |
67 | 67 | 0.714 |
68 | 68 | 0.386 |
69 | 69 | 0.592 |
7 | 7 | 0.284 |
70 | 70 | 0.0681 |
71 | 71 | 0.0485 |
72 | 72 | 0.301 |
73 | 73 | 0.234 |
74 | 74 | 0.183 |
75 | 75 | 0.0754 |
76 | 76 | 0.0815 |
77 | 77 | 0.611 |
78 | 78 | 0.264 |
79 | 79 | 0.695 |
8 | 8 | 0.946 |
80 | 80 | 0.0364 |
81 | 81 | 0.374 |
82 | 82 | 0.129 |
83 | 83 | 0.419 |
84 | 84 | 0.0907 |
85 | 85 | 0.0698 |
86 | 86 | 0.0236 |
87 | 87 | 0.443 |
88 | 88 | 0.785 |
89 | 89 | 0.679 |
9 | 9 | 0.457 |
90 | 90 | 0.134 |
91 | 91 | 0.227 |
92 | 92 | 0.316 |
93 | 93 | 0.866 |
94 | 94 | 0.0846 |
95 | 95 | 0.189 |
96 | 96 | 0.476 |
97 | 97 | 0.987 |
98 | 98 | 0.136 |
99 | 99 | 0.00342 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11958
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000135 human peripheral blood mononuclear cell sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0002371 (somatic cell)
0000219 (motile cell)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0000255 (eukaryotic cell)
0000226 (single nucleate cell)
0000080 (circulating cell)
0000842 (mononuclear cell)
UBERON: Anatomy
0000468 (multi-cellular organism)
0000178 (blood)
0004120 (mesoderm-derived structure)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000179 (haemolymphatic fluid)
0000463 (organism substance)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0010317 (germ layer / neural crest derived structure)
0002390 (hematopoietic system)
0004535 (cardiovascular system)
0002193 (hemolymphoid system)
0001009 (circulatory system)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)
0000135 (human peripheral blood mononuclear cell sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)