FF:10845-111E8: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005137 | ||
| | |accession_numbers=CAGE;DRX007949;DRR008821;DRZ000246;DRZ001631;DRZ011596;DRZ012981 | ||
| | |ancestors_in_anatomy_facet=UBERON:0002384,UBERON:0000479,UBERON:0000061,UBERON:0000465,UBERON:0001062 | ||
| | |ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0002320,CL:0000066,CL:0002371,CL:0000076,CL:0000213,CL:0000215,CL:0000255,CL:0000057,CL:0000077 | ||
|ancestors_in_disease_facet=DOID:4,DOID:162,DOID:14566,DOID:0050687,DOID:1115 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100453,FF:0100400,FF:0100460,FF:0102424,FF:0103764 | |||
|comment= | |||
| | |created_by= | ||
|creation_date= | |||
| | |data_phase=2 | ||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr17:36105042..36105060,-!p1@HNF1B!2.12!130.43!HNF1B;;chr1:201979743..201979762,+!p1@ELF3!2.00!99.42!ELF3;;chr1:201979703..201979721,+!p2@ELF3!1.88!74.05!ELF3;;chr3:69915385..69915438,+!p3@MITF!1.84!67.65!MITF;;chr2:114036488..114036504,-!p1@PAX8!1.79!61.24!PAX8;;chr3:69915369..69915381,+!p4@MITF!1.68!47.40!MITF;;chr3:69812798..69812824,+!p8@MITF!1.60!38.44!MITF;;chr3:69812745..69812760,+!p10@MITF!1.45!27.16!MITF;;chr3:69812701..69812729,+!p9@MITF!1.40!24.34!MITF;;chr7:28448965..28448994,+!p2@CREB5!1.38!78.67!CREB5;;chr11:61520075..61520136,+!p1@C11orf9!1.38!47.66!C11orf9;;chr6:19837592..19837621,+!p1@ID4!1.36!129.15!ID4;;chr3:69812731..69812742,+!p19@MITF!1.32!19.73!MITF;;chr6:10412600..10412637,-!p1@TFAP2A!1.27!28.96!TFAP2A;;chr9:126774018..126774055,+!p1@LHX2!1.23!15.89!LHX2;;chr3:141043020..141043049,+!p17@ZBTB38!1.19!14.61!ZBTB38;;chr18:55102598..55102623,+!p1@ONECUT2!1.19!14.35!ONECUT2;;chr10:102505493..102505546,+!p2@PAX2!1.17!13.84!PAX2;;chr5:124082322..124082364,-!p1@ZNF608!1.12!31.01!ZNF608;;chr7:28452130..28452154,+!p10@CREB5!1.12!12.04!CREB5;;chr4:87928142..87928165,+!p5@AFF1!1.09!38.69!AFF1;;chr3:69812649..69812658,+!p20@MITF!1.09!11.27!MITF;;chr3:69812764..69812775,+!p18@MITF!1.07!10.76!MITF;;chr4:87928166..87928186,+!p12@AFF1!1.06!16.40!AFF1;;chr8:76319876..76319926,+!p1@HNF4G!1.02!9.48!HNF4G;;chr12:100867653..100867677,+!p2@NR1H4!1.02!9.48!NR1H4;;chr3:69812852..69812864,+!p17@MITF!1.00!8.97!MITF;;chr9:4300050..4300118,-!p1@GLIS3!0.99!57.91!GLIS3;;chr6:10415276..10415341,-!p2@TFAP2A!0.99!10.76!TFAP2A;;chr3:69811858..69811881,+!p5@MITF!0.99!8.71!MITF;;chr18:55102628..55102646,+!p2@ONECUT2!0.99!8.71!ONECUT2;;chr3:141043050..141043063,+!p22@ZBTB38!0.98!8.46!ZBTB38;;chr17:79881332..79881348,-!p3@MAFG!0.97!12.30!MAFG;;chr5:176738887..176738934,-!p1@MXD3!0.96!55.60!MXD3;;chr3:170076314..170076334,+!p2@SKIL!0.96!10.76!SKIL;;chr16:51185172..51185197,-!p1@SALL1!0.96!8.20!SALL1;;chrY:21906594..21906622,-!p1@KDM5D!0.95!7.94!KDM5D;;chr5:124081979..124082021,-!p7@ZNF608!0.94!7.69!ZNF608;;chr5:174151553..174151610,+!p1@MSX2!0.92!12.56!MSX2;;chr17:46703687..46703740,-!p1@HOXB9!0.91!7.17!HOXB9;;chr13:41593425..41593480,-!p1@ELF1!0.88!43.82!ELF1;;chr11:706938..707008,-!p3@DEAF1!0.88!8.46!DEAF1;;chr12:100867627..100867652,+!p1@NR1H4!0.88!6.66!NR1H4;;chr7:156803329..156803362,-!p1@MNX1!0.88!6.66!MNX1;;chr10:51572408..51572454,+!p3@NCOA4!0.87!39.20!NCOA4;;chr5:124082279..124082319,-!p3@ZNF608!0.87!7.94!ZNF608;;chr6:10412392..10412409,-!p4@TFAP2A!0.86!7.17!TFAP2A;;chr20:30193083..30193098,+!p1@ID1!0.85!521.71!ID1;;chr15:67357924..67357952,+!p2@SMAD3!0.85!43.05!SMAD3;;chr3:69812877..69812886,+!p22@MITF!0.85!6.15!MITF;;chr4:87928105..87928126,+!p13@AFF1!0.84!9.22!AFF1;;chr11:120107344..120107351,+!p1@POU2F3!0.83!7.17!POU2F3;;chr6:21593973..21593988,+!p1@SOX4!0.82!218.32!SOX4;;chr2:242556880..242556899,-!p5@THAP4!0.82!5.64!THAP4;;chr3:24536253..24536328,-!p1@THRB!0.81!10.76!THRB;;chr16:54320646..54320672,-!p2@IRX3!0.81!8.71!IRX3;;chr7:28725740..28725778,+!p1@CREB5!0.80!51.76!CREB5;;chr2:63277948..63277974,+!p1@OTX1!0.80!5.38!OTX1;;chr17:36104873..36104903,-!p3@HNF1B!0.80!5.38!HNF1B;;chr1:151804244..151804310,-!p1@RORC!0.80!5.38!RORC;;chr5:76383133..76383186,-!p2@ZBED3!0.79!11.27!ZBED3;;chr5:76383070..76383117,-!p3@ZBED3!0.79!11.02!ZBED3;;chr5:174151612..174151633,+!p2@MSX2!0.79!5.12!MSX2;;chr16:54320617..54320643,-!p3@IRX3!0.78!6.66!IRX3;;chr15:66994561..66994597,+!p2@SMAD6!0.77!12.56!SMAD6;;chr15:66994615..66994630,+!p3@SMAD6!0.77!7.17!SMAD6;;chr17:36105074..36105086,-!p2@HNF1B!0.77!4.87!HNF1B;;chr7:101917407..101917443,+!p3@CUX1!0.77!4.87!CUX1;;chr2:8822176..8822196,+!p1@ID2!0.75!716.20!ID2;;chr16:4366053..4366076,+!p@chr16:4366053..4366076,+!0.75!50.99!GLIS2;;chr5:124080203..124080258,-!p5@ZNF608!0.75!5.38!ZNF608;;chr20:22564895..22564910,-!p1@FOXA2!0.75!4.61!FOXA2;;chr2:176994408..176994492,+!p1@HOXD8!0.75!4.61!HOXD8;;chr7:128577972..128578047,+!p1@IRF5!0.73!7.17!IRF5;;chr5:172662197..172662216,-!p1@NKX2-5!0.73!4.36!NKX2-5;;chr19:58373157..58373159,+!p4@ZNF587!0.72!8.20!ZNF587;;chrX:129402866..129402880,-!p1@ZNF280C!0.71!26.65!ZNF280C;;chr1:41174988..41175047,+!p4@NFYC!0.71!12.04!NFYC;;chr11:63684602..63684664,-!p1@RCOR2!0.71!8.71!RCOR2;;chr6:21597514..21597578,+!p4@SOX4!0.71!7.43!SOX4;;chr3:12330560..12330579,+!p1@PPARG!0.71!4.87!PPARG;;chr5:124082470..124082483,-!p8@ZNF608!0.71!4.10!ZNF608;;chr6:21597765..21597779,+!p2@SOX4!0.70!36.90!SOX4;;chr3:69788576..69788648,+!p1@MITF!0.69!23.57!MITF;;chr2:122042770..122042785,-!p1@TFCP2L1!0.69!3.84!TFCP2L1;;chr17:48045917..48045977,+!p1@DLX4!0.69!3.84!DLX4;;chr12:80084279..80084293,-!p8@PAWR!0.68!6.66!PAWR;;chr3:101546827..101546847,+!p2@NFKBIZ!0.68!5.64!NFKBIZ;;chr4:87857474..87857489,+!p7@AFF1!0.67!6.92!AFF1;;chr12:80083544..80083558,-!p13@PAWR!0.67!4.87!PAWR;;chr16:1429627..1429662,-!p2@UNKL!0.66!11.79!UNKL;;chr7:28725715..28725727,+!p3@CREB5!0.66!4.36!CREB5;;chr13:41593493..41593506,-!p8@ELF1!0.66!3.59!ELF1;;chr3:69811882..69811898,+!p6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| |||
|ffid_belonging_in_development=CL:0000134,CL:0000222 | |||
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| | |||
|fonse_cell_line=FF:0100400,FF:0100453,FF:0102424 | |fonse_cell_line=FF:0100400,FF:0100453,FF:0102424 | ||
|fonse_cell_line_closure=FF:0100400,FF:0100453,FF:0102424 | |fonse_cell_line_closure=FF:0100400,FF:0100453,FF:0102424 | ||
Line 66: | Line 40: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/mesothelioma%2520cell%2520line%253aNCI-H28.CNhs13061.10845-111E8.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/mesothelioma%2520cell%2520line%253aNCI-H28.CNhs13061.10845-111E8.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/mesothelioma%2520cell%2520line%253aNCI-H28.CNhs13061.10845-111E8.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/mesothelioma%2520cell%2520line%253aNCI-H28.CNhs13061.10845-111E8.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/mesothelioma%2520cell%2520line%253aNCI-H28.CNhs13061.10845-111E8.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10845-111E8 | |||
|is_a=EFO:0002091;;FF:0000210;;FF:0102424;;FF:0103764 | |||
|is_obsolete= | |||
|library_id=CNhs13061 | |||
|library_id_phase_based=2:CNhs13061 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10845 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10845 | |||
|name=mesothelioma cell line:NCI-H28 | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs13061,LSID1000,release012,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0.0495365713353616,0,0,0,0,0.0193724825589684,0,0.0561357938753371,0.262100588052594,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0943371949604506,0,0,0,0,0,0.149702309040821,0,0,-0.033883447108139,0,0,0,0,0,0,0,0,0,0,0,0,0.0374534855450617,0,0,0,0,0,0,0,0,0.074858121557889,0,0,0,0,0,0,0,0.209425390335127,0,0,0.0017295154576263,0,0,0,0,0,0,0,0,0.0990731426707233,0,0,0,0,0,0,0,0,0.032386155013311,0.0495365713353616,0,0,0,0,0,-0.00966655792986115,0.173366673989801,0,0,-0.0584468268118252,-0.161660831360507,0,0,0,0,0.208382400340026,0.130450459748423,0,0,0,0,0,0,0,0,0,0,0.247660205308878,0,0,0,0,0,0,0.0827088103041805,0,0,0,0.0536162488432144,0.139571125785428,0,0,0.0990731426707233,0,0,0 | |||
|repeat_enrich_byname=0,0,0,0.306417751577732,0.208382400340026,0,0,0.179690512645354,0,0.0990731426707233,0.247660205308878,0.0990731426707233,0,0,0,0,-0.247178875285564,0,0.0452394437821044,-0.0444419998527486,0,0,-0.167616255642514,0,0,0,0,0,0.0990731426707233,0,0,0,-0.128119866952565,0,-0.0504125515893149,0,0,0,0,-0.0186252810838506,-0.305472230898407,0,-0.0844128048268325,0.336053080167317,0,0,0,0,-0.0968739953445236,0,-0.0218063411230174,-0.0827201683234173,0.224566723098164,-0.293345791164243,-0.04680465889238,0,0,0,-0.431760047739903,0.0883934828572837,0,0,-0.031934595429197,-0.028140742771793,0,0,-0.391044581551635,0,-0.382046421083614,0.100640037207481,0,0.244345540225491,0,0,0,0,0,0,0,0,0.0990731426707233,0,0.0990731426707233,-0.00795689548607485,0.031176211774314,0.0990731426707233,0,0.0990731426707233,0,-0.239348982505238,0,0.0458473214234601,0.263316040252039,0.0367857750928715,0.0245044450273162,0.126944244961494,0,0.143788584191058,-0.172053336494252,-0.0740934579634519,-0.0084873747450045,-0.147401849371139,-0.0102912069044929,0,-0.234877148603765,0.201045508126659,0.100270840072228,-0.0856345037399662,0.0177578585281392,0.126155298104157,0.0970244173974135,0,0,0,-0.280853609455039,0,-0.144961520359507,-0.131949906023491,0.0255305119298044,-0.38003212785162,0.174002050576825,0.0064663796205172,0.141897374199014,0.0998492992013681,-0.0530391116519098,0,-0.268363449114834,-0.146182655982906,0,0,-0.0343359178601647,-0.301621929324932,0.222617067198645,0,-0.384904319140257,-0.0683442610773682,0,0.412755011795434,-0.130726533745166,0.446178311200971,0,-0.331117025562534,0,0,0.0504721557321921,0,0.179690512645354,0.0591989638981636,-0.440419000359443,0.0148046437533335,0,-0.061379887912366,0,-0.0455508383948824,0,-0.0568506080561183,-0.0147304957703616,0,-0.180964130423922,0,-0.117521912553227,-0.33849706049483,0.07952723106808,-0.323321662721014,-0.0584468268118252,-0.0453016208275198,-0.224090473967935,-0.173361593494054,-0.0397953241685868,-0.0252345539226902,-0.0881268324752877,-0.0365796715384787,-0.198374437570169,-0.580424988950801,-0.104981777711649,-0.119112377596075,0,-0.0635597419443852,0,-0.0797494671326826,0,-0.632305925357992,-0.54043375147324,0.329244309808716,-0.0415844396721157,0,-0.292845144652474,0.88980395116019,0,0.0457109727128527,0,0.0990731426707233,-0.150367083334639,0.107197670980061,-0.162113856529227,-0.089452885343833,0,-0.483662406811924,0,0,-0.313184424562821,0.401126158444217,0,-0.101208856030105,0.0523619219145995,0.032386155013311,-0.0168979307642108,0.358164808453283,0,-0.546627195322001,0,0,-0.247763255364747,-0.0717894763714536,-0.00966655792986115,-0.253326341486756,-0.072161261117404,0.849765112490138,0,0,-0.177527765965176,0,-0.0713831331123985,0,0,-0.0362059376217073,0.084871841522117,0,0.202198670622343,0,-0.0427254476979537,0,0,0,0,0,0,0,0.197894717938942,0.529524658703841,0,0.0273215924504084,0,0,0,0,0,-0.0648274647664463,0,0,-1.59233083881968,0.11880085517231,-0.023944273005697,0,0,0,0,0.336021130886108,0.201160779149961,0.179690512645354,-0.131862706497632,0,0,0,0,0.161519215519667,0,0,0.179082404226642,0.0495365713353616,0.0413426856170593,0.093064732011661,0,0,0,0.0812104068514924,0,0,0,0,0.226195659965973,0,0,0,0,-0.0869941786627331,0.0174912631238818,0,-0.420847120535129,-1.30415547722674,0.750212711432582,0,0,-0.261347131789888,0,0,0.0345421622901312,0,0.179690512645354,0,0,0,0,0,0,0,0.269975665382635,0,0,0,0,0.179690512645354,0,0,0.0990731426707233,0,0,0,-0.415183640323457,-0.0922240566585104,-0.0640596705171081,0,0,0,0,0,0,-0.0241060230789031,0.0201991313371203,0,0,0,0,0,0.0990731426707233,0,0,0.412932049257047,0.247660205308878,0,0,0,0,0.209425390335127,0,0,0,0.0990731426707233,0.524201176105187,0,0,-0.178288989522791,0,0,0,0,0,0,0.0160292157878797,0,0,0,0,0,0,-0.123319086035448,0.0561357938753371,0,0,0,0,0,0,0,0.307077319042093,0,0,0,0,-0.113884373708977,0,0,0,0.142863820519722,0,0.0193724825589684,0,0,0,0,0,0.00311373529713638,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.390828726621291,0.0247609925551393,-0.28720751597291,-0.0268611317058794,0,0,-0.0535459484064005,0,0,0,0,0,0,0.092489678625912,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0146785275302732,0,0,0,0,0,0,0,0.149702309040821,0,0,-0.0920328098005262,0,0,0,0,0.373908204305864,0,0.473829936006058,-0.283220399823148,-0.0285767034144636,0,0,0.0990731426707233,-0.00484900114709335,0,0,0,0,-0.0667773874189013,0,0,0,0,0,0,0,0,0.0990731426707233,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0943371949604506,0,0,0,0,0,0,0,0,0,0,0,0,0.153208875788866,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0340113632754165,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0800184682686384,0,0,0,-0.0333957170116892,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.00103152570570963,0,0,0,0,0,0,0,0,0,0,0,0,0,0.199438130069824,0,0.0953138804153273,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0860981536928932,0,0,0,0,0.0514360320098044,0,0,0,0,0,0,0,0.037048616144193,0,0,0,0,0,0,0,0,0,0,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| |||
|rna_box=111 | |||
|rna_catalog_number= | |||
|rna_concentration=1.2658 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=2.07 | |||
|rna_od260/280=2.06 | |||
|rna_position=E8 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=1.11E+10 | |||
|rna_weight_ug=94.935 | |||
|sample_age=48 | |||
|sample_category=cell lines | |||
|sample_cell_catalog=CRL5820 | |||
|sample_cell_line=NCI-H28 | |||
|sample_cell_lot= | |||
|sample_cell_type=mesothelial cell | |||
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest) | |||
|sample_company=ATCC | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=mesothelioma | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=C | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;3.37340775922332e-264!GO:0043226;organelle;2.89442480085241e-224!GO:0043229;intracellular organelle;8.41647560668846e-224!GO:0043231;intracellular membrane-bound organelle;6.26934117264531e-222!GO:0043227;membrane-bound organelle;6.26934117264531e-222!GO:0005737;cytoplasm;3.6468377585962e-176!GO:0044422;organelle part;8.36795402815509e-164!GO:0044446;intracellular organelle part;4.24188041244868e-162!GO:0044444;cytoplasmic part;1.83987093536954e-130!GO:0032991;macromolecular complex;7.30363690764771e-112!GO:0044237;cellular metabolic process;1.20706019435431e-107!GO:0044238;primary metabolic process;1.59094530017314e-102!GO:0005634;nucleus;5.88806093677145e-100!GO:0030529;ribonucleoprotein complex;3.1397721765074e-98!GO:0043170;macromolecule metabolic process;9.40153660231686e-97!GO:0044428;nuclear part;9.77313612566764e-89!GO:0003723;RNA binding;1.11418587124087e-85!GO:0043233;organelle lumen;3.0204016164491e-84!GO:0031974;membrane-enclosed lumen;3.0204016164491e-84!GO:0005739;mitochondrion;1.87114255655239e-81!GO:0005515;protein binding;1.85647659703657e-66!GO:0006396;RNA processing;6.14078625268987e-61!GO:0005840;ribosome;7.01484428062218e-58!GO:0043283;biopolymer metabolic process;1.44178739040333e-57!GO:0044429;mitochondrial part;9.37408822735443e-57!GO:0043234;protein complex;1.01831516085265e-55!GO:0006412;translation;1.14229864352149e-54!GO:0019538;protein metabolic process;3.61219417207002e-53!GO:0031090;organelle membrane;1.01789829971689e-52!GO:0010467;gene expression;1.81584714957939e-52!GO:0031981;nuclear lumen;2.99967275904715e-52!GO:0003735;structural constituent of ribosome;3.09613047749141e-51!GO:0016043;cellular component organization and biogenesis;2.82980051126769e-50!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;3.16675010302835e-50!GO:0031967;organelle envelope;6.20432302208004e-50!GO:0031975;envelope;9.13667444273976e-50!GO:0044260;cellular macromolecule metabolic process;3.37778357819357e-47!GO:0044267;cellular protein metabolic process;3.40497178567013e-47!GO:0016071;mRNA metabolic process;4.61509241799908e-46!GO:0033036;macromolecule localization;1.26537451134884e-44!GO:0033279;ribosomal subunit;2.38218534257012e-44!GO:0015031;protein transport;2.40339985158791e-44!GO:0008380;RNA splicing;4.14732488973788e-44!GO:0044249;cellular biosynthetic process;5.75150954820759e-44!GO:0009058;biosynthetic process;1.20179100009702e-43!GO:0009059;macromolecule biosynthetic process;4.58358923506996e-42!GO:0005829;cytosol;7.74364494700014e-41!GO:0008104;protein localization;2.07728637886789e-40!GO:0006397;mRNA processing;2.93447559873252e-40!GO:0043228;non-membrane-bound organelle;9.14648651184364e-40!GO:0043232;intracellular non-membrane-bound organelle;9.14648651184364e-40!GO:0045184;establishment of protein localization;1.14881475014246e-39!GO:0046907;intracellular transport;1.6298986537431e-37!GO:0006996;organelle organization and biogenesis;6.27395189592174e-36!GO:0005740;mitochondrial envelope;2.73208590963257e-35!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.40854542452786e-34!GO:0006259;DNA metabolic process;4.48454099669892e-34!GO:0019866;organelle inner membrane;7.70058378855662e-34!GO:0000166;nucleotide binding;1.84611129643721e-33!GO:0031966;mitochondrial membrane;2.3307621199689e-33!GO:0003676;nucleic acid binding;4.53181620911251e-33!GO:0065003;macromolecular complex assembly;5.14662346401404e-33!GO:0005654;nucleoplasm;2.02784081910834e-31!GO:0005743;mitochondrial inner membrane;3.66315281748008e-31!GO:0005681;spliceosome;4.64552738827706e-31!GO:0005830;cytosolic ribosome (sensu Eukaryota);4.86952548527923e-31!GO:0006886;intracellular protein transport;1.11361825135195e-29!GO:0022607;cellular component assembly;2.72759162835422e-29!GO:0007049;cell cycle;2.79117237910931e-29!GO:0044445;cytosolic part;2.37375710021418e-26!GO:0006974;response to DNA damage stimulus;1.84563570158144e-25!GO:0006119;oxidative phosphorylation;2.05745353719696e-25!GO:0051649;establishment of cellular localization;5.83105067356467e-25!GO:0016070;RNA metabolic process;1.1846850299292e-24!GO:0031980;mitochondrial lumen;1.48663269588911e-24!GO:0005759;mitochondrial matrix;1.48663269588911e-24!GO:0051641;cellular localization;1.90032017520777e-24!GO:0044451;nucleoplasm part;2.16911690114227e-24!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;2.3745768674645e-24!GO:0016462;pyrophosphatase activity;2.54036829154642e-24!GO:0016817;hydrolase activity, acting on acid anhydrides;2.91327362159147e-24!GO:0044455;mitochondrial membrane part;4.60027360070635e-24!GO:0017111;nucleoside-triphosphatase activity;7.81496174511288e-24!GO:0032553;ribonucleotide binding;2.62867567916778e-23!GO:0032555;purine ribonucleotide binding;2.62867567916778e-23!GO:0015934;large ribosomal subunit;8.51693321878854e-23!GO:0017076;purine nucleotide binding;1.12318467293636e-22!GO:0005730;nucleolus;1.17694739348961e-22!GO:0015935;small ribosomal subunit;1.22425983731301e-22!GO:0000278;mitotic cell cycle;5.41838272202865e-22!GO:0016874;ligase activity;2.36669081368976e-21!GO:0022402;cell cycle process;2.38134839213351e-21!GO:0006281;DNA repair;2.69903611361135e-21!GO:0044265;cellular macromolecule catabolic process;7.58699773240534e-21!GO:0012505;endomembrane system;1.80019277745478e-20!GO:0032559;adenyl ribonucleotide binding;2.26785278163053e-20!GO:0051186;cofactor metabolic process;2.59539455512502e-20!GO:0005524;ATP binding;3.03750304848859e-20!GO:0022618;protein-RNA complex assembly;5.55731714720768e-20!GO:0005746;mitochondrial respiratory chain;6.33131010537305e-20!GO:0006457;protein folding;8.05134389042198e-20!GO:0030554;adenyl nucleotide binding;1.65798173521719e-19!GO:0006512;ubiquitin cycle;3.64540538149586e-19!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;4.119753018122e-19!GO:0000087;M phase of mitotic cell cycle;5.93404994805814e-18!GO:0007067;mitosis;9.57219748009592e-18!GO:0005761;mitochondrial ribosome;1.31946685214104e-17!GO:0000313;organellar ribosome;1.31946685214104e-17!GO:0044248;cellular catabolic process;1.35854689953551e-17!GO:0009719;response to endogenous stimulus;1.39837543464445e-17!GO:0050136;NADH dehydrogenase (quinone) activity;1.6634627294285e-17!GO:0003954;NADH dehydrogenase activity;1.6634627294285e-17!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.6634627294285e-17!GO:0008135;translation factor activity, nucleic acid binding;3.33304434167035e-17!GO:0016887;ATPase activity;3.59700088969733e-17!GO:0009057;macromolecule catabolic process;3.8391674068261e-17!GO:0005694;chromosome;4.55651803048612e-17!GO:0006511;ubiquitin-dependent protein catabolic process;5.77274241353483e-17!GO:0042623;ATPase activity, coupled;5.85472563693997e-17!GO:0051603;proteolysis involved in cellular protein catabolic process;6.65499339414039e-17!GO:0022403;cell cycle phase;8.7589534738175e-17!GO:0019941;modification-dependent protein catabolic process;8.81018151654832e-17!GO:0043632;modification-dependent macromolecule catabolic process;8.81018151654832e-17!GO:0043412;biopolymer modification;9.21460220502782e-17!GO:0044257;cellular protein catabolic process;1.20124735323396e-16!GO:0043285;biopolymer catabolic process;1.97734069389554e-16!GO:0006732;coenzyme metabolic process;2.30047117457184e-16!GO:0048770;pigment granule;2.90652270232834e-16!GO:0042470;melanosome;2.90652270232834e-16!GO:0008134;transcription factor binding;3.13029879109611e-16!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);3.78344929972319e-16!GO:0051301;cell division;4.44962721672387e-16!GO:0042775;organelle ATP synthesis coupled electron transport;4.93189700276764e-16!GO:0042773;ATP synthesis coupled electron transport;4.93189700276764e-16!GO:0000398;nuclear mRNA splicing, via spliceosome;5.21329770226782e-16!GO:0000375;RNA splicing, via transesterification reactions;5.21329770226782e-16!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;5.21329770226782e-16!GO:0005635;nuclear envelope;5.49897409267645e-16!GO:0006260;DNA replication;5.80241566637907e-16!GO:0030964;NADH dehydrogenase complex (quinone);9.30462725869756e-16!GO:0045271;respiratory chain complex I;9.30462725869756e-16!GO:0005747;mitochondrial respiratory chain complex I;9.30462725869756e-16!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);2.13170067869183e-15!GO:0042254;ribosome biogenesis and assembly;2.8357386113455e-15!GO:0006605;protein targeting;2.8357386113455e-15!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;3.05531346714564e-15!GO:0031965;nuclear membrane;3.83642708051719e-15!GO:0000502;proteasome complex (sensu Eukaryota);5.74795601102465e-15!GO:0044427;chromosomal part;7.45983685569736e-15!GO:0044453;nuclear membrane part;7.70962684825904e-15!GO:0000279;M phase;1.07845298701705e-14!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.13446971619477e-14!GO:0051082;unfolded protein binding;1.23987769254251e-14!GO:0006464;protein modification process;1.37488359381931e-14!GO:0006399;tRNA metabolic process;2.25906613296703e-14!GO:0005783;endoplasmic reticulum;7.73581395321922e-14!GO:0051276;chromosome organization and biogenesis;1.46215851188421e-13!GO:0009055;electron carrier activity;3.49087983688445e-13!GO:0030163;protein catabolic process;5.01715100746667e-13!GO:0005643;nuclear pore;5.39915861582642e-13!GO:0005794;Golgi apparatus;6.36856600149845e-13!GO:0003743;translation initiation factor activity;9.69340359153729e-13!GO:0016604;nuclear body;9.85394845604758e-13!GO:0043687;post-translational protein modification;1.41181058384239e-12!GO:0004386;helicase activity;2.54263476557481e-12!GO:0006413;translational initiation;3.11294024225403e-12!GO:0048193;Golgi vesicle transport;3.6792493028319e-12!GO:0006461;protein complex assembly;1.20617288838442e-11!GO:0006403;RNA localization;1.39013937990752e-11!GO:0065002;intracellular protein transport across a membrane;1.54431779721563e-11!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;2.2045543055736e-11!GO:0004812;aminoacyl-tRNA ligase activity;2.2045543055736e-11!GO:0016875;ligase activity, forming carbon-oxygen bonds;2.2045543055736e-11!GO:0012501;programmed cell death;2.2045543055736e-11!GO:0016192;vesicle-mediated transport;2.22923282626319e-11!GO:0050657;nucleic acid transport;3.1063727430794e-11!GO:0051236;establishment of RNA localization;3.1063727430794e-11!GO:0050658;RNA transport;3.1063727430794e-11!GO:0044432;endoplasmic reticulum part;3.84235013347534e-11!GO:0003712;transcription cofactor activity;4.46234333620997e-11!GO:0043038;amino acid activation;4.82391467709598e-11!GO:0006418;tRNA aminoacylation for protein translation;4.82391467709598e-11!GO:0043039;tRNA aminoacylation;4.82391467709598e-11!GO:0006915;apoptosis;5.04786230254749e-11!GO:0046930;pore complex;5.98095377778139e-11!GO:0007005;mitochondrion organization and biogenesis;6.56636914284982e-11!GO:0045333;cellular respiration;7.95721612080224e-11!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.08721083016693e-10!GO:0006446;regulation of translational initiation;1.11581567802667e-10!GO:0008026;ATP-dependent helicase activity;1.12534233982154e-10!GO:0015630;microtubule cytoskeleton;1.17230433263407e-10!GO:0006913;nucleocytoplasmic transport;1.19222305154036e-10!GO:0006364;rRNA processing;1.50258245116844e-10!GO:0006325;establishment and/or maintenance of chromatin architecture;1.57222313850439e-10!GO:0000074;regulation of progression through cell cycle;1.7162596568268e-10!GO:0009060;aerobic respiration;1.73145038186667e-10!GO:0051188;cofactor biosynthetic process;1.83625623175517e-10!GO:0051726;regulation of cell cycle;2.15455124917299e-10!GO:0009056;catabolic process;2.35964534585345e-10!GO:0016072;rRNA metabolic process;2.49457211693371e-10!GO:0009259;ribonucleotide metabolic process;2.90704767148436e-10!GO:0051169;nuclear transport;3.1503375839104e-10!GO:0006323;DNA packaging;4.53542394663568e-10!GO:0006163;purine nucleotide metabolic process;5.76112584384064e-10!GO:0008219;cell death;6.22022502489347e-10!GO:0016265;death;6.22022502489347e-10!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;6.67953550312609e-10!GO:0016607;nuclear speck;7.40425467221233e-10!GO:0006164;purine nucleotide biosynthetic process;7.75252897654352e-10!GO:0009260;ribonucleotide biosynthetic process;9.99081559651793e-10!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.30737370840587e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;1.32148420924729e-09!GO:0030532;small nuclear ribonucleoprotein complex;1.32148420924729e-09!GO:0051028;mRNA transport;1.59684756697211e-09!GO:0009150;purine ribonucleotide metabolic process;2.06795361881438e-09!GO:0008639;small protein conjugating enzyme activity;2.5009100919692e-09!GO:0009152;purine ribonucleotide biosynthetic process;2.73974344893148e-09!GO:0006366;transcription from RNA polymerase II promoter;3.43713310745295e-09!GO:0008565;protein transporter activity;3.61179164160751e-09!GO:0016568;chromatin modification;4.24100670994034e-09!GO:0006099;tricarboxylic acid cycle;4.84871783598102e-09!GO:0046356;acetyl-CoA catabolic process;4.84871783598102e-09!GO:0004842;ubiquitin-protein ligase activity;5.90379530667846e-09!GO:0016740;transferase activity;6.25876741261563e-09!GO:0003697;single-stranded DNA binding;7.13419113994583e-09!GO:0043566;structure-specific DNA binding;8.0178875629832e-09!GO:0019787;small conjugating protein ligase activity;8.32238227697421e-09!GO:0006084;acetyl-CoA metabolic process;8.34489239001748e-09!GO:0051187;cofactor catabolic process;8.7178620272068e-09!GO:0015986;ATP synthesis coupled proton transport;8.93174148640628e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;8.93174148640628e-09!GO:0042175;nuclear envelope-endoplasmic reticulum network;9.50641237382896e-09!GO:0009108;coenzyme biosynthetic process;1.00523399353255e-08!GO:0006261;DNA-dependent DNA replication;1.62333193014492e-08!GO:0005789;endoplasmic reticulum membrane;1.82981964996866e-08!GO:0009199;ribonucleoside triphosphate metabolic process;1.82981964996866e-08!GO:0017038;protein import;2.03663117006737e-08!GO:0009141;nucleoside triphosphate metabolic process;2.2649085489544e-08!GO:0009142;nucleoside triphosphate biosynthetic process;2.42557402436449e-08!GO:0009201;ribonucleoside triphosphate biosynthetic process;2.42557402436449e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;3.24170329392715e-08!GO:0009144;purine nucleoside triphosphate metabolic process;3.24170329392715e-08!GO:0050794;regulation of cellular process;3.94721527558293e-08!GO:0005793;ER-Golgi intermediate compartment;3.94721527558293e-08!GO:0019829;cation-transporting ATPase activity;4.04058298831433e-08!GO:0015078;hydrogen ion transmembrane transporter activity;4.11957421455527e-08!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;4.37001038398712e-08!GO:0009145;purine nucleoside triphosphate biosynthetic process;4.37001038398712e-08!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;5.65786573627731e-08!GO:0000775;chromosome, pericentric region;5.68164603041098e-08!GO:0016881;acid-amino acid ligase activity;6.86610074493786e-08!GO:0005819;spindle;7.11013539274959e-08!GO:0006754;ATP biosynthetic process;9.88704817258268e-08!GO:0006753;nucleoside phosphate metabolic process;9.88704817258268e-08!GO:0046034;ATP metabolic process;1.02784171816373e-07!GO:0009109;coenzyme catabolic process;1.22061850525901e-07!GO:0006793;phosphorus metabolic process;1.25301581424654e-07!GO:0006796;phosphate metabolic process;1.25301581424654e-07!GO:0032446;protein modification by small protein conjugation;1.26232187881994e-07!GO:0016469;proton-transporting two-sector ATPase complex;1.31995207445657e-07!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.44930582933601e-07!GO:0000245;spliceosome assembly;1.47936396431495e-07!GO:0043067;regulation of programmed cell death;1.66987019548163e-07!GO:0042981;regulation of apoptosis;2.22861832421556e-07!GO:0005768;endosome;2.56039656537719e-07!GO:0016567;protein ubiquitination;2.67596772995788e-07!GO:0000785;chromatin;3.5040085710396e-07!GO:0045259;proton-transporting ATP synthase complex;3.64991118612841e-07!GO:0005667;transcription factor complex;4.61278877520153e-07!GO:0016491;oxidoreductase activity;4.855700430948e-07!GO:0005815;microtubule organizing center;6.05386228681285e-07!GO:0016787;hydrolase activity;6.43755919686964e-07!GO:0005813;centrosome;6.43755919686964e-07!GO:0043623;cellular protein complex assembly;6.86917294779683e-07!GO:0016310;phosphorylation;8.71136827663031e-07!GO:0044431;Golgi apparatus part;9.16098055265191e-07!GO:0006752;group transfer coenzyme metabolic process;1.12153096467896e-06!GO:0008094;DNA-dependent ATPase activity;1.1680608340179e-06!GO:0009117;nucleotide metabolic process;1.341257217422e-06!GO:0051427;hormone receptor binding;1.67966115667338e-06!GO:0007051;spindle organization and biogenesis;1.85481160753701e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.91050152278472e-06!GO:0005762;mitochondrial large ribosomal subunit;1.95023910593525e-06!GO:0000315;organellar large ribosomal subunit;1.95023910593525e-06!GO:0065004;protein-DNA complex assembly;1.95315617225141e-06!GO:0000151;ubiquitin ligase complex;1.95315617225141e-06!GO:0043069;negative regulation of programmed cell death;2.42429496664416e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;2.44686664006295e-06!GO:0006888;ER to Golgi vesicle-mediated transport;2.61142317754993e-06!GO:0015980;energy derivation by oxidation of organic compounds;2.68045059551371e-06!GO:0051329;interphase of mitotic cell cycle;2.84584379527799e-06!GO:0048475;coated membrane;2.88366291951765e-06!GO:0030117;membrane coat;2.88366291951765e-06!GO:0003714;transcription corepressor activity;3.06412769512965e-06!GO:0016779;nucleotidyltransferase activity;3.24501661956204e-06!GO:0035257;nuclear hormone receptor binding;4.06517179519215e-06!GO:0030120;vesicle coat;4.35878721707724e-06!GO:0030662;coated vesicle membrane;4.35878721707724e-06!GO:0006091;generation of precursor metabolites and energy;5.77358950349918e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;6.00596599224825e-06!GO:0043066;negative regulation of apoptosis;6.18328182851801e-06!GO:0008654;phospholipid biosynthetic process;6.64461001928408e-06!GO:0005657;replication fork;7.42816895323034e-06!GO:0048523;negative regulation of cellular process;8.4223559222079e-06!GO:0006839;mitochondrial transport;9.55185046275551e-06!GO:0005839;proteasome core complex (sensu Eukaryota);9.6098602968666e-06!GO:0006302;double-strand break repair;9.76534213992239e-06!GO:0042802;identical protein binding;9.84488328786484e-06!GO:0051325;interphase;1.03840378694857e-05!GO:0003690;double-stranded DNA binding;1.08274264795283e-05!GO:0006333;chromatin assembly or disassembly;1.09820432710866e-05!GO:0016563;transcription activator activity;1.20852758072011e-05!GO:0006613;cotranslational protein targeting to membrane;1.68039587801252e-05!GO:0000314;organellar small ribosomal subunit;1.89518910434543e-05!GO:0005763;mitochondrial small ribosomal subunit;1.89518910434543e-05!GO:0016564;transcription repressor activity;1.98272329771592e-05!GO:0019222;regulation of metabolic process;1.99220622191846e-05!GO:0003924;GTPase activity;2.12309899480024e-05!GO:0003724;RNA helicase activity;2.23576326632459e-05!GO:0043021;ribonucleoprotein binding;2.23576326632459e-05!GO:0044440;endosomal part;2.37960270006024e-05!GO:0010008;endosome membrane;2.37960270006024e-05!GO:0006606;protein import into nucleus;2.51092912781609e-05!GO:0000075;cell cycle checkpoint;2.82915491519219e-05!GO:0051170;nuclear import;2.82930352735845e-05!GO:0005770;late endosome;2.82930352735845e-05!GO:0003713;transcription coactivator activity;2.9538447529331e-05!GO:0051246;regulation of protein metabolic process;2.99962155740436e-05!GO:0019899;enzyme binding;3.28787070121176e-05!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;3.28787070121176e-05!GO:0015399;primary active transmembrane transporter activity;3.28787070121176e-05!GO:0045454;cell redox homeostasis;3.45809457222175e-05!GO:0004298;threonine endopeptidase activity;3.50458919467402e-05!GO:0000139;Golgi membrane;3.57132105754305e-05!GO:0051052;regulation of DNA metabolic process;4.40890814413264e-05!GO:0005525;GTP binding;4.52911405548831e-05!GO:0051168;nuclear export;4.55488761471922e-05!GO:0007006;mitochondrial membrane organization and biogenesis;4.90126302098251e-05!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;5.00864059764517e-05!GO:0003899;DNA-directed RNA polymerase activity;5.03535774652946e-05!GO:0045786;negative regulation of progression through cell cycle;5.08060474857017e-05!GO:0006916;anti-apoptosis;5.09730901430043e-05!GO:0008033;tRNA processing;5.13258087440382e-05!GO:0031324;negative regulation of cellular metabolic process;5.24147675165794e-05!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;5.71762804915897e-05!GO:0007017;microtubule-based process;6.39820193465009e-05!GO:0006357;regulation of transcription from RNA polymerase II promoter;6.68785843138529e-05!GO:0007010;cytoskeleton organization and biogenesis;7.35217431291406e-05!GO:0005753;mitochondrial proton-transporting ATP synthase complex;7.62977399039623e-05!GO:0008022;protein C-terminus binding;8.03062543499489e-05!GO:0016853;isomerase activity;8.43817076742641e-05!GO:0046467;membrane lipid biosynthetic process;9.25766891278201e-05!GO:0000776;kinetochore;9.45617942914615e-05!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.000102796135117506!GO:0003684;damaged DNA binding;0.000107183962501254!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;0.000109761977721526!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000125249816133618!GO:0006626;protein targeting to mitochondrion;0.000131537209511182!GO:0048471;perinuclear region of cytoplasm;0.000138700163514754!GO:0048519;negative regulation of biological process;0.000139393454781231!GO:0005769;early endosome;0.000148053828223991!GO:0003682;chromatin binding;0.000153972724763362!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000153972724763362!GO:0005874;microtubule;0.000162553632091832!GO:0019843;rRNA binding;0.000173552243044918!GO:0003729;mRNA binding;0.000173552243044918!GO:0050789;regulation of biological process;0.000176559603832462!GO:0009892;negative regulation of metabolic process;0.000178862897249048!GO:0009165;nucleotide biosynthetic process;0.000183857433954642!GO:0044452;nucleolar part;0.000195215798694942!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.000198302802956871!GO:0019752;carboxylic acid metabolic process;0.000199559018482321!GO:0043681;protein import into mitochondrion;0.000204311083861987!GO:0006082;organic acid metabolic process;0.000241294453041546!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000259075572457634!GO:0006414;translational elongation;0.000270338668998838!GO:0007088;regulation of mitosis;0.000270338668998838!GO:0006401;RNA catabolic process;0.000272214551496244!GO:0006352;transcription initiation;0.000284313306935883!GO:0006402;mRNA catabolic process;0.000284401558326182!GO:0016363;nuclear matrix;0.000286877209535601!GO:0008186;RNA-dependent ATPase activity;0.000302881225040687!GO:0046474;glycerophospholipid biosynthetic process;0.000311602689645788!GO:0005905;coated pit;0.000312717509909538!GO:0030867;rough endoplasmic reticulum membrane;0.00032446446291502!GO:0043492;ATPase activity, coupled to movement of substances;0.000326553370199665!GO:0031988;membrane-bound vesicle;0.000340253866575857!GO:0031252;leading edge;0.000381691324803799!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000388607107337187!GO:0005885;Arp2/3 protein complex;0.000393462765238151!GO:0065009;regulation of a molecular function;0.000411852345062533!GO:0035258;steroid hormone receptor binding;0.000433741195069861!GO:0005798;Golgi-associated vesicle;0.00044074323998052!GO:0030880;RNA polymerase complex;0.000457066668647409!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000457893604385604!GO:0006383;transcription from RNA polymerase III promoter;0.000460982831707726!GO:0032561;guanyl ribonucleotide binding;0.000466660419472237!GO:0019001;guanyl nucleotide binding;0.000466660419472237!GO:0033116;ER-Golgi intermediate compartment membrane;0.000479115603729577!GO:0003678;DNA helicase activity;0.000479664802293196!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000492762162061757!GO:0016023;cytoplasmic membrane-bound vesicle;0.000492762162061757!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000531583231586134!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000531583231586134!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000531583231586134!GO:0006310;DNA recombination;0.00054084191171107!GO:0000059;protein import into nucleus, docking;0.000548704393349557!GO:0031323;regulation of cellular metabolic process;0.000578516449879595!GO:0006612;protein targeting to membrane;0.00057874566119095!GO:0005741;mitochondrial outer membrane;0.00061305344051036!GO:0044262;cellular carbohydrate metabolic process;0.000626163646434206!GO:0031968;organelle outer membrane;0.000626163646434206!GO:0008629;induction of apoptosis by intracellular signals;0.000663682928596317!GO:0007059;chromosome segregation;0.000663932642468263!GO:0004576;oligosaccharyl transferase activity;0.000723412639577795!GO:0046489;phosphoinositide biosynthetic process;0.000725608820587298!GO:0019867;outer membrane;0.000749406625316475!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000755047750352093!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.000757002552258582!GO:0006007;glucose catabolic process;0.000771808368228269!GO:0051252;regulation of RNA metabolic process;0.000777377344500165!GO:0006350;transcription;0.000855727660945757!GO:0005684;U2-dependent spliceosome;0.000883456579264523!GO:0004004;ATP-dependent RNA helicase activity;0.000883456579264523!GO:0016251;general RNA polymerase II transcription factor activity;0.000895025249871369!GO:0007052;mitotic spindle organization and biogenesis;0.000895025249871369!GO:0016741;transferase activity, transferring one-carbon groups;0.000907354768379593!GO:0008250;oligosaccharyl transferase complex;0.000916199128062639!GO:0007093;mitotic cell cycle checkpoint;0.000933158026767391!GO:0008168;methyltransferase activity;0.000939344353639343!GO:0016859;cis-trans isomerase activity;0.00094354967554693!GO:0005637;nuclear inner membrane;0.000977577037632312!GO:0015992;proton transport;0.000983984177969539!GO:0005788;endoplasmic reticulum lumen;0.00100878339655176!GO:0006749;glutathione metabolic process;0.00101682243712529!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00103679651885537!GO:0000428;DNA-directed RNA polymerase complex;0.00103679651885537!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00103679651885537!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00103679651885537!GO:0006520;amino acid metabolic process;0.00105324132779764!GO:0015631;tubulin binding;0.00111502932900018!GO:0006650;glycerophospholipid metabolic process;0.00111502932900018!GO:0007264;small GTPase mediated signal transduction;0.00112674447497032!GO:0006818;hydrogen transport;0.00114009910475986!GO:0031982;vesicle;0.00116598555227697!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.00117793051155196!GO:0004527;exonuclease activity;0.00132745916707514!GO:0050662;coenzyme binding;0.00134444068066026!GO:0016481;negative regulation of transcription;0.00160116032434488!GO:0030521;androgen receptor signaling pathway;0.00166757697712455!GO:0032508;DNA duplex unwinding;0.00170996944749954!GO:0032392;DNA geometric change;0.00170996944749954!GO:0004674;protein serine/threonine kinase activity;0.00171287045484675!GO:0031410;cytoplasmic vesicle;0.00176160889377721!GO:0051087;chaperone binding;0.00188109137230028!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00190338957730077!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00208975523118078!GO:0015002;heme-copper terminal oxidase activity;0.00208975523118078!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00208975523118078!GO:0004129;cytochrome-c oxidase activity;0.00208975523118078!GO:0048487;beta-tubulin binding;0.00210047742886429!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00215751088240977!GO:0005048;signal sequence binding;0.00220111086987439!GO:0006891;intra-Golgi vesicle-mediated transport;0.00237224178220519!GO:0016044;membrane organization and biogenesis;0.00237224178220519!GO:0016272;prefoldin complex;0.00237776213292964!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00254456265183771!GO:0016281;eukaryotic translation initiation factor 4F complex;0.0025633955853012!GO:0046483;heterocycle metabolic process;0.00265016067645352!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00267558309581594!GO:0048500;signal recognition particle;0.00285671848918336!GO:0006275;regulation of DNA replication;0.00309728257885641!GO:0030118;clathrin coat;0.00309728257885641!GO:0006268;DNA unwinding during replication;0.00312172201267322!GO:0006611;protein export from nucleus;0.00314479486330347!GO:0046365;monosaccharide catabolic process;0.00315046120485255!GO:0003746;translation elongation factor activity;0.0031857994137621!GO:0045893;positive regulation of transcription, DNA-dependent;0.00340828666523421!GO:0006338;chromatin remodeling;0.00340828666523421!GO:0016197;endosome transport;0.00349854436836972!GO:0000049;tRNA binding;0.00364932172380478!GO:0051287;NAD binding;0.00364932172380478!GO:0042770;DNA damage response, signal transduction;0.0036566102336304!GO:0006778;porphyrin metabolic process;0.0036566102336304!GO:0033013;tetrapyrrole metabolic process;0.0036566102336304!GO:0006672;ceramide metabolic process;0.00368959744109846!GO:0008632;apoptotic program;0.00370338372783582!GO:0046983;protein dimerization activity;0.00382017390467047!GO:0006289;nucleotide-excision repair;0.00395326748417261!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00416760131155522!GO:0005996;monosaccharide metabolic process;0.00416760131155522!GO:0048468;cell development;0.00424685030183649!GO:0000287;magnesium ion binding;0.00426791029899426!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.00455105125791143!GO:0000922;spindle pole;0.00464677055351754!GO:0046519;sphingoid metabolic process;0.00477907573906114!GO:0006096;glycolysis;0.00478849794605626!GO:0006334;nucleosome assembly;0.00481987817904906!GO:0007243;protein kinase cascade;0.0048472300840662!GO:0019318;hexose metabolic process;0.00489995658875122!GO:0008312;7S RNA binding;0.00489995658875122!GO:0048522;positive regulation of cellular process;0.00489995658875122!GO:0043488;regulation of mRNA stability;0.00499976171213621!GO:0043487;regulation of RNA stability;0.00499976171213621!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00517093365144533!GO:0019320;hexose catabolic process;0.00554035824904475!GO:0050681;androgen receptor binding;0.00561897805496284!GO:0045045;secretory pathway;0.00566340034617019!GO:0046164;alcohol catabolic process;0.00568995015718362!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00569193439702834!GO:0031497;chromatin assembly;0.00581753450891199!GO:0000792;heterochromatin;0.00591885045189175!GO:0051789;response to protein stimulus;0.00599711574139489!GO:0006986;response to unfolded protein;0.00599711574139489!GO:0000086;G2/M transition of mitotic cell cycle;0.00600840647091435!GO:0030384;phosphoinositide metabolic process;0.00608927147815442!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00621706842044189!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00635495891169327!GO:0006405;RNA export from nucleus;0.00655778334367869!GO:0018196;peptidyl-asparagine modification;0.0066367319190004!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0066367319190004!GO:0030132;clathrin coat of coated pit;0.00671663895109329!GO:0006497;protein amino acid lipidation;0.00673829433147881!GO:0043022;ribosome binding;0.00686434952363995!GO:0030176;integral to endoplasmic reticulum membrane;0.00695694683898254!GO:0043624;cellular protein complex disassembly;0.006964525947452!GO:0008139;nuclear localization sequence binding;0.00706510114880771!GO:0042168;heme metabolic process;0.00712322330903586!GO:0000339;RNA cap binding;0.00714100925538489!GO:0010468;regulation of gene expression;0.00720713780949454!GO:0006284;base-excision repair;0.00720713780949454!GO:0030119;AP-type membrane coat adaptor complex;0.00721364264298124!GO:0030036;actin cytoskeleton organization and biogenesis;0.00752622415705836!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00753270569006234!GO:0045047;protein targeting to ER;0.00753270569006234!GO:0005758;mitochondrial intermembrane space;0.00760387688201925!GO:0008234;cysteine-type peptidase activity;0.00764505765554409!GO:0000152;nuclear ubiquitin ligase complex;0.0077149708481668!GO:0022890;inorganic cation transmembrane transporter activity;0.00778521050844159!GO:0006144;purine base metabolic process;0.00819056546488954!GO:0005876;spindle microtubule;0.00841129448435625!GO:0006376;mRNA splice site selection;0.00847538587956352!GO:0000389;nuclear mRNA 3'-splice site recognition;0.00847538587956352!GO:0031625;ubiquitin protein ligase binding;0.00853025313716192!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00875348327886474!GO:0030663;COPI coated vesicle membrane;0.00877393236313119!GO:0030126;COPI vesicle coat;0.00877393236313119!GO:0003711;transcription elongation regulator activity;0.00897451142839913!GO:0043284;biopolymer biosynthetic process;0.00899589017521982!GO:0001726;ruffle;0.00927726198879938!GO:0006595;polyamine metabolic process;0.00937905751010228!GO:0031902;late endosome membrane;0.00948640937166565!GO:0005832;chaperonin-containing T-complex;0.00991131379226244!GO:0030131;clathrin adaptor complex;0.00992874388532278!GO:0031124;mRNA 3'-end processing;0.0102263358340825!GO:0032984;macromolecular complex disassembly;0.0104639382086739!GO:0050178;phenylpyruvate tautomerase activity;0.0104694161081213!GO:0031072;heat shock protein binding;0.0104719779220817!GO:0005773;vacuole;0.0105360667844738!GO:0005853;eukaryotic translation elongation factor 1 complex;0.0106687518004889!GO:0000725;recombinational repair;0.0107003744142952!GO:0000724;double-strand break repair via homologous recombination;0.0107003744142952!GO:0030658;transport vesicle membrane;0.0109527458788612!GO:0031570;DNA integrity checkpoint;0.0110889863115469!GO:0006740;NADPH regeneration;0.0110889863115469!GO:0006098;pentose-phosphate shunt;0.0110889863115469!GO:0030659;cytoplasmic vesicle membrane;0.0110889863115469!GO:0051539;4 iron, 4 sulfur cluster binding;0.0111335828135032!GO:0004003;ATP-dependent DNA helicase activity;0.0114419670548073!GO:0008610;lipid biosynthetic process;0.0114419670548073!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0115723901813357!GO:0004518;nuclease activity;0.0115723901813357!GO:0004448;isocitrate dehydrogenase activity;0.0118158136802147!GO:0042393;histone binding;0.0122121642180096!GO:0043065;positive regulation of apoptosis;0.0124319863492066!GO:0006506;GPI anchor biosynthetic process;0.0124760386311037!GO:0031901;early endosome membrane;0.0124943350668456!GO:0004177;aminopeptidase activity;0.0126686277687433!GO:0030503;regulation of cell redox homeostasis;0.0128693388591136!GO:0051101;regulation of DNA binding;0.0130770339816221!GO:0045941;positive regulation of transcription;0.0132338871197466!GO:0005791;rough endoplasmic reticulum;0.0133004180296985!GO:0051920;peroxiredoxin activity;0.0134312219541675!GO:0048037;cofactor binding;0.0139445442252568!GO:0031970;organelle envelope lumen;0.0139445442252568!GO:0051098;regulation of binding;0.0140481845863053!GO:0009303;rRNA transcription;0.0140732798305185!GO:0000096;sulfur amino acid metabolic process;0.0141442861127668!GO:0006643;membrane lipid metabolic process;0.0155060398972087!GO:0043068;positive regulation of programmed cell death;0.0156096595878738!GO:0006270;DNA replication initiation;0.016189591124206!GO:0016628;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;0.0163504308604387!GO:0046966;thyroid hormone receptor binding;0.0166991899943464!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0166991899943464!GO:0004192;cathepsin D activity;0.0169455569022754!GO:0009116;nucleoside metabolic process;0.0172704837386426!GO:0044433;cytoplasmic vesicle part;0.0173620133628277!GO:0000209;protein polyubiquitination;0.0173757425237846!GO:0017166;vinculin binding;0.017544544815334!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0176893619281872!GO:0008180;signalosome;0.0176893619281872!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0178809816144797!GO:0006505;GPI anchor metabolic process;0.0178821045634204!GO:0042158;lipoprotein biosynthetic process;0.0180231965202578!GO:0009451;RNA modification;0.0184075960763917!GO:0008601;protein phosphatase type 2A regulator activity;0.0184770682081002!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0184814891487215!GO:0043189;H4/H2A histone acetyltransferase complex;0.0185853213270148!GO:0051540;metal cluster binding;0.0187047414641115!GO:0051536;iron-sulfur cluster binding;0.0187047414641115!GO:0043241;protein complex disassembly;0.0188826689812616!GO:0030125;clathrin vesicle coat;0.0190363280094973!GO:0030665;clathrin coated vesicle membrane;0.0190363280094973!GO:0012506;vesicle membrane;0.0190363280094973!GO:0004532;exoribonuclease activity;0.0191017874257892!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0191017874257892!GO:0016407;acetyltransferase activity;0.01937650270912!GO:0006118;electron transport;0.0194821840578431!GO:0009112;nucleobase metabolic process;0.0194988513636666!GO:0016408;C-acyltransferase activity;0.0194988513636666!GO:0008092;cytoskeletal protein binding;0.0195024176938194!GO:0000178;exosome (RNase complex);0.0196560118943479!GO:0030660;Golgi-associated vesicle membrane;0.0199447783238096!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0199447783238096!GO:0016301;kinase activity;0.0199447783238096!GO:0043596;nuclear replication fork;0.0200629348963173!GO:0030518;steroid hormone receptor signaling pathway;0.0201596463130187!GO:0051128;regulation of cellular component organization and biogenesis;0.0201596463130187!GO:0008017;microtubule binding;0.0203825218767438!GO:0004680;casein kinase activity;0.0204734102892873!GO:0005663;DNA replication factor C complex;0.0205869190697511!GO:0045920;negative regulation of exocytosis;0.0205869190697511!GO:0043301;negative regulation of leukocyte degranulation;0.0205869190697511!GO:0043305;negative regulation of mast cell degranulation;0.0205869190697511!GO:0043130;ubiquitin binding;0.0206375158945414!GO:0032182;small conjugating protein binding;0.0206375158945414!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.0209505169716611!GO:0047485;protein N-terminus binding;0.0209875744378494!GO:0008408;3'-5' exonuclease activity;0.0210918080890154!GO:0030137;COPI-coated vesicle;0.0210918080890154!GO:0035267;NuA4 histone acetyltransferase complex;0.0214288869421332!GO:0016616;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;0.0214875632577127!GO:0006509;membrane protein ectodomain proteolysis;0.0215484109295244!GO:0033619;membrane protein proteolysis;0.0215484109295244!GO:0050790;regulation of catalytic activity;0.0218182653522454!GO:0032774;RNA biosynthetic process;0.0221980163350483!GO:0031123;RNA 3'-end processing;0.0225050686932908!GO:0022415;viral reproductive process;0.0225497422879129!GO:0032200;telomere organization and biogenesis;0.0226998577914109!GO:0000723;telomere maintenance;0.0226998577914109!GO:0006730;one-carbon compound metabolic process;0.0227077225894276!GO:0051053;negative regulation of DNA metabolic process;0.0229866684063511!GO:0022411;cellular component disassembly;0.0229866684063511!GO:0005875;microtubule associated complex;0.0234354809948247!GO:0003725;double-stranded RNA binding;0.0234354809948247!GO:0030134;ER to Golgi transport vesicle;0.0241114824634916!GO:0047115;trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity;0.0243323199410477!GO:0006351;transcription, DNA-dependent;0.0249255114837368!GO:0000123;histone acetyltransferase complex;0.0257055100075573!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0260543257234379!GO:0010257;NADH dehydrogenase complex assembly;0.0260543257234379!GO:0033108;mitochondrial respiratory chain complex assembly;0.0260543257234379!GO:0008637;apoptotic mitochondrial changes;0.026169560844015!GO:0000819;sister chromatid segregation;0.0264778669206175!GO:0005869;dynactin complex;0.0268324305245233!GO:0006979;response to oxidative stress;0.0269496348971799!GO:0006695;cholesterol biosynthetic process;0.0270904332826868!GO:0006006;glucose metabolic process;0.027843447994625!GO:0006220;pyrimidine nucleotide metabolic process;0.028472211697703!GO:0006519;amino acid and derivative metabolic process;0.0291941168323147!GO:0000077;DNA damage checkpoint;0.0292454395961307!GO:0007021;tubulin folding;0.0297562151912066!GO:0000070;mitotic sister chromatid segregation;0.0298103347377648!GO:0030508;thiol-disulfide exchange intermediate activity;0.0302002185718649!GO:0043433;negative regulation of transcription factor activity;0.0308971745410964!GO:0046822;regulation of nucleocytoplasmic transport;0.0309346347705673!GO:0004347;glucose-6-phosphate isomerase activity;0.0309431436017906!GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors;0.0316530183594604!GO:0000323;lytic vacuole;0.0316530183594604!GO:0005764;lysosome;0.0316530183594604!GO:0051348;negative regulation of transferase activity;0.0322535799217145!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0323107289690767!GO:0000726;non-recombinational repair;0.0323772735018785!GO:0000082;G1/S transition of mitotic cell cycle;0.0324312718313468!GO:0006779;porphyrin biosynthetic process;0.0326750671411813!GO:0033014;tetrapyrrole biosynthetic process;0.0326750671411813!GO:0005669;transcription factor TFIID complex;0.0327893567004852!GO:0015036;disulfide oxidoreductase activity;0.0328674794927312!GO:0032259;methylation;0.0329657119316769!GO:0044275;cellular carbohydrate catabolic process;0.0334504886400568!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0336422434467251!GO:0051881;regulation of mitochondrial membrane potential;0.0336422434467251!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0337259383621315!GO:0045039;protein import into mitochondrial inner membrane;0.0337259383621315!GO:0006739;NADP metabolic process;0.0340567768541124!GO:0033673;negative regulation of kinase activity;0.0341104266716831!GO:0006469;negative regulation of protein kinase activity;0.0341104266716831!GO:0019206;nucleoside kinase activity;0.03421460831036!GO:0005784;translocon complex;0.0342532649452613!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0344298611076343!GO:0030029;actin filament-based process;0.0344298611076343!GO:0003955;NAD(P)H dehydrogenase (quinone) activity;0.0348805169833388!GO:0006733;oxidoreduction coenzyme metabolic process;0.0355244200873552!GO:0050811;GABA receptor binding;0.0355244200873552!GO:0006378;mRNA polyadenylation;0.0356611261414769!GO:0006516;glycoprotein catabolic process;0.0359356189022218!GO:0043414;biopolymer methylation;0.0362714487198177!GO:0000781;chromosome, telomeric region;0.0370011245111802!GO:0006301;postreplication repair;0.037334099523982!GO:0000159;protein phosphatase type 2A complex;0.0377285263512365!GO:0000228;nuclear chromosome;0.0379448497226343!GO:0016018;cyclosporin A binding;0.0384714789867891!GO:0007050;cell cycle arrest;0.0387124436604531!GO:0019783;small conjugating protein-specific protease activity;0.0390501072348123!GO:0006266;DNA ligation;0.0391216301124679!GO:0006892;post-Golgi vesicle-mediated transport;0.0400193061640567!GO:0006400;tRNA modification;0.0408433774983613!GO:0008097;5S rRNA binding;0.0409682245485777!GO:0006950;response to stress;0.0409682245485777!GO:0030496;midbody;0.0410615836816557!GO:0005680;anaphase-promoting complex;0.0410615836816557!GO:0007030;Golgi organization and biogenesis;0.0417225706710433!GO:0006081;aldehyde metabolic process;0.0417488645624983!GO:0000118;histone deacetylase complex;0.0417488645624983!GO:0004843;ubiquitin-specific protease activity;0.0421473810027767!GO:0016614;oxidoreductase activity, acting on CH-OH group of donors;0.0424308259646508!GO:0051338;regulation of transferase activity;0.0437837095407168!GO:0005652;nuclear lamina;0.0437935948648696!GO:0006767;water-soluble vitamin metabolic process;0.0439483005554054!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0439483005554054!GO:0031056;regulation of histone modification;0.0454840468383734!GO:0008276;protein methyltransferase activity;0.0455028053616714!GO:0042791;5S class rRNA transcription;0.0455028053616714!GO:0000127;transcription factor TFIIIC complex;0.0455028053616714!GO:0042797;tRNA transcription from RNA polymerase III promoter;0.0455028053616714!GO:0048144;fibroblast proliferation;0.0455545598106052!GO:0048145;regulation of fibroblast proliferation;0.0455545598106052!GO:0008287;protein serine/threonine phosphatase complex;0.0455582600777287!GO:0005521;lamin binding;0.0461297421023912!GO:0046982;protein heterodimerization activity;0.047160846849294!GO:0003988;acetyl-CoA C-acyltransferase activity;0.0474214322285734!GO:0000303;response to superoxide;0.0476686385236097!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.0478232471599998!GO:0048146;positive regulation of fibroblast proliferation;0.0482072342401775!GO:0004197;cysteine-type endopeptidase activity;0.0482072342401775!GO:0030133;transport vesicle;0.0482072342401775!GO:0016126;sterol biosynthetic process;0.0484140800318287!GO:0030911;TPR domain binding;0.0493685829955443!GO:0031371;ubiquitin conjugating enzyme complex;0.0493685829955443!GO:0045449;regulation of transcription;0.0494779051589763 | |||
|sample_id=10845 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=mesothelium | |||
|top_motifs=ALX1:2.5683885444;HNF1A:2.32232672315;ESRRA:1.68006445815;ONECUT1,2:1.66037127975;ELK1,4_GABP{A,B1}:1.57537485811;FOXQ1:1.47497941771;ZBTB16:1.38749254881;MYOD1:1.30528672375;RXRA_VDR{dimer}:1.26001703362;LHX3,4:1.25394598609;NKX6-1,2:1.22903264296;EVI1:1.1536838603;E2F1..5:1.13038684942;NR5A1,2:0.998439836535;NFE2L2:0.997287364723;NR6A1:0.958202794661;PITX1..3:0.945248168651;NKX2-1,4:0.906368232562;ADNP_IRX_SIX_ZHX:0.889826320321;NRF1:0.841333363694;PAX5:0.833725077318;CDX1,2,4:0.792704480747;MYB:0.78389355272;STAT5{A,B}:0.743023170298;ZNF143:0.729688748219;AIRE:0.718268148745;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.680921453714;NKX3-2:0.662277848875;HIF1A:0.657305486486;HNF4A_NR2F1,2:0.653807125228;RORA:0.648883261733;HOX{A6,A7,B6,B7}:0.620804718261;RXR{A,B,G}:0.578666104479;NFE2:0.55718000215;ALX4:0.542684789083;bHLH_family:0.537180906704;SOX2:0.532553184865;NFY{A,B,C}:0.517597637979;UFEwm:0.488791153508;HAND1,2:0.465614526739;PBX1:0.420330773784;YY1:0.397603892098;TEF:0.382617305454;DBP:0.354128618236;TBX4,5:0.335970208093;PAX4:0.329131712244;XCPE1{core}:0.324521864361;LEF1_TCF7_TCF7L1,2:0.287595042011;ARID5B:0.262116498941;SNAI1..3:0.250892070302;IKZF2:0.243800866926;TOPORS:0.238387281669;NANOG:0.233817973471;NR1H4:0.231111734551;FOXP3:0.219727678856;NFE2L1:0.209168303784;NKX3-1:0.208375144107;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.203955679362;POU1F1:0.182366624451;CUX2:0.178421822756;ZFP161:0.166523156643;ZEB1:0.165455619665;EN1,2:0.153660368402;GFI1:0.144836810935;NKX2-2,8:0.144345524748;IKZF1:0.130485232729;TEAD1:0.112593268814;TP53:0.100593819031;HOXA9_MEIS1:0.0880034285576;BREu{core}:0.0846039801342;NFIX:0.0802029434746;FOXM1:0.0735333360002;HOX{A4,D4}:0.071470533572;OCT4_SOX2{dimer}:0.0662170379136;FOSL2:0.0585591785826;FOX{F1,F2,J1}:0.0580817267211;ZIC1..3:0.0512844937144;FOXP1:0.0400905403546;SOX17:0.033725375485;PDX1:0.031184211012;ELF1,2,4:0.0279869389276;HOX{A5,B5}:0.0180099466879;FOXN1:-0.0191131359374;LMO2:-0.0290831904315;POU6F1:-0.0387724902963;XBP1:-0.0417612024862;FOXD3:-0.0453675765518;PRRX1,2:-0.0481560318471;RFX1:-0.0996104464747;RBPJ:-0.109619076108;TFDP1:-0.110530364515;MTE{core}:-0.132515407661;CDC5L:-0.133990939783;NFKB1_REL_RELA:-0.151308586552;STAT1,3:-0.157552251594;EP300:-0.160121642593;FOXA2:-0.162415113723;PAX8:-0.173302372507;CREB1:-0.176388950045;POU5F1:-0.176666785583;TFAP2{A,C}:-0.178929067918;MZF1:-0.184612796857;AHR_ARNT_ARNT2:-0.186154860561;POU3F1..4:-0.186341153475;BACH2:-0.189121224545;GFI1B:-0.209431615665;KLF4:-0.209843533857;ATF2:-0.210001156014;PAX6:-0.242403637323;ZNF423:-0.242995591352;TFCP2:-0.250264049736;AR:-0.250369368386;PAX1,9:-0.253526587362;RFX2..5_RFXANK_RFXAP:-0.258195984953;EGR1..3:-0.278496993077;ESR1:-0.287041883498;FOS_FOS{B,L1}_JUN{B,D}:-0.297145815591;RREB1:-0.300807844968;PPARG:-0.316628913627;ZNF384:-0.323976834025;MAZ:-0.324610920471;GTF2I:-0.337381524797;PAX2:-0.363843682727;CEBPA,B_DDIT3:-0.366156554932;PATZ1:-0.375082746188;TLX1..3_NFIC{dimer}:-0.380059822661;CRX:-0.385478289142;BPTF:-0.410963046112;TFAP2B:-0.462118306514;NKX2-3_NKX2-5:-0.469221617788;MEF2{A,B,C,D}:-0.479056857648;T:-0.481303139004;SP1:-0.482929027078;GATA6:-0.485752655727;FOXL1:-0.487589478325;STAT2,4,6:-0.495311940592;GATA4:-0.516749221637;SPIB:-0.526815480325;HIC1:-0.532891409877;SPI1:-0.549529169515;IRF7:-0.554088150455;SOX{8,9,10}:-0.561408002798;ATF5_CREB3:-0.593693916809;POU2F1..3:-0.602270436108;RUNX1..3:-0.604256382225;EBF1:-0.606263600848;ZNF148:-0.620349118584;MYBL2:-0.621511895029;NR3C1:-0.621965283856;ATF4:-0.641479145316;PRDM1:-0.663116262787;TAL1_TCF{3,4,12}:-0.665633921555;FOX{I1,J2}:-0.698444727833;SPZ1:-0.702447421241;HLF:-0.716678255445;DMAP1_NCOR{1,2}_SMARC:-0.766063080953;NFIL3:-0.773727312125;ETS1,2:-0.780149522063;GZF1:-0.817892133885;SREBF1,2:-0.833821740156;MED-1{core}:-0.839392931089;REST:-0.861029710127;FOX{D1,D2}:-0.870145712054;SOX5:-0.87070012268;TGIF1:-0.915541945245;GLI1..3:-0.926112372127;HES1:-0.927441711894;PAX3,7:-0.960173603718;NFATC1..3:-0.961665436875;IRF1,2:-0.96801019083;GTF2A1,2:-0.99826398999;ZBTB6:-1.00457121923;MYFfamily:-1.02325526903;MTF1:-1.0403458207;HSF1,2:-1.04142215325;VSX1,2:-1.04212600219;JUN:-1.05284394591;HMGA1,2:-1.06563147036;FOXO1,3,4:-1.08204613885;NANOG{mouse}:-1.0860502152;GCM1,2:-1.23614337574;TBP:-1.243282624;NHLH1,2:-1.29429294329;SRF:-1.32496774583;MAFB:-1.35050533598;HMX1:-1.37025462819;ZNF238:-1.41879801171;TLX2:-1.42504390787;HBP1_HMGB_SSRP1_UBTF:-1.53330505642;SMAD1..7,9:-1.53523469897;ATF6:-1.65623338812;TFAP4:-1.67213728144 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10845-111E8;search_select_hide=table117:FF:10845-111E8 | |||
}} | }} |
Latest revision as of 15:09, 3 June 2020
Name: | mesothelioma cell line:NCI-H28 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs13061 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13061
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13061
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.153 |
10 | 10 | 0.112 |
100 | 100 | 0.076 |
101 | 101 | 0.312 |
102 | 102 | 0.286 |
103 | 103 | 0.4 |
104 | 104 | 0.651 |
105 | 105 | 0.345 |
106 | 106 | 0.026 |
107 | 107 | 0.0537 |
108 | 108 | 0.423 |
109 | 109 | 0.255 |
11 | 11 | 0.826 |
110 | 110 | 0.401 |
111 | 111 | 0.306 |
112 | 112 | 0.354 |
113 | 113 | 0.0997 |
114 | 114 | 0.522 |
115 | 115 | 0.729 |
116 | 116 | 0.505 |
117 | 117 | 0.264 |
118 | 118 | 0.0799 |
119 | 119 | 0.905 |
12 | 12 | 0.65 |
120 | 120 | 0.776 |
121 | 121 | 0.824 |
122 | 122 | 0.745 |
123 | 123 | 0.278 |
124 | 124 | 0.284 |
125 | 125 | 0.726 |
126 | 126 | 0.939 |
127 | 127 | 0.205 |
128 | 128 | 5.87253e-4 |
129 | 129 | 0.331 |
13 | 13 | 1.03006e-4 |
130 | 130 | 0.827 |
131 | 131 | 0.777 |
132 | 132 | 0.246 |
133 | 133 | 0.032 |
134 | 134 | 0.327 |
135 | 135 | 0.369 |
136 | 136 | 0.00678 |
137 | 137 | 0.149 |
138 | 138 | 0.344 |
139 | 139 | 0.203 |
14 | 14 | 0.551 |
140 | 140 | 0.155 |
141 | 141 | 0.542 |
142 | 142 | 0.674 |
143 | 143 | 0.0442 |
144 | 144 | 0.969 |
145 | 145 | 0.346 |
146 | 146 | 0.827 |
147 | 147 | 0.848 |
148 | 148 | 0.919 |
149 | 149 | 0.692 |
15 | 15 | 0.629 |
150 | 150 | 0.878 |
151 | 151 | 0.588 |
152 | 152 | 0.028 |
153 | 153 | 0.511 |
154 | 154 | 0.394 |
155 | 155 | 0.78 |
156 | 156 | 0.823 |
157 | 157 | 0.619 |
158 | 158 | 0.532 |
159 | 159 | 0.845 |
16 | 16 | 0.914 |
160 | 160 | 0.365 |
161 | 161 | 0.91 |
162 | 162 | 0.696 |
163 | 163 | 0.815 |
164 | 164 | 0.836 |
165 | 165 | 0.732 |
166 | 166 | 0.739 |
167 | 167 | 0.2 |
168 | 168 | 0.87 |
169 | 169 | 0.79 |
17 | 17 | 0.278 |
18 | 18 | 0.401 |
19 | 19 | 0.383 |
2 | 2 | 0.0778 |
20 | 20 | 0.164 |
21 | 21 | 0.964 |
22 | 22 | 0.619 |
23 | 23 | 0.0628 |
24 | 24 | 0.159 |
25 | 25 | 0.77 |
26 | 26 | 0.309 |
27 | 27 | 0.614 |
28 | 28 | 0.542 |
29 | 29 | 0.189 |
3 | 3 | 0.845 |
30 | 30 | 0.199 |
31 | 31 | 0.595 |
32 | 32 | 0.0705 |
33 | 33 | 0.656 |
34 | 34 | 0.0856 |
35 | 35 | 0.648 |
36 | 36 | 0.463 |
37 | 37 | 0.916 |
38 | 38 | 0.858 |
39 | 39 | 0.39 |
4 | 4 | 0.918 |
40 | 40 | 0.612 |
41 | 41 | 0.0128 |
42 | 42 | 0.788 |
43 | 43 | 0.576 |
44 | 44 | 0.107 |
45 | 45 | 0.564 |
46 | 46 | 0.56 |
47 | 47 | 0.473 |
48 | 48 | 0.734 |
49 | 49 | 0.525 |
5 | 5 | 0.202 |
50 | 50 | 0.902 |
51 | 51 | 0.327 |
52 | 52 | 0.0779 |
53 | 53 | 0.242 |
54 | 54 | 0.722 |
55 | 55 | 0.805 |
56 | 56 | 0.878 |
57 | 57 | 0.359 |
58 | 58 | 0.657 |
59 | 59 | 0.725 |
6 | 6 | 0.851 |
60 | 60 | 0.159 |
61 | 61 | 0.194 |
62 | 62 | 0.465 |
63 | 63 | 0.927 |
64 | 64 | 0.847 |
65 | 65 | 0.312 |
66 | 66 | 0.443 |
67 | 67 | 0.865 |
68 | 68 | 0.635 |
69 | 69 | 0.254 |
7 | 7 | 0.755 |
70 | 70 | 0.784 |
71 | 71 | 0.169 |
72 | 72 | 0.54 |
73 | 73 | 0.235 |
74 | 74 | 0.31 |
75 | 75 | 0.237 |
76 | 76 | 0.75 |
77 | 77 | 0.466 |
78 | 78 | 0.0162 |
79 | 79 | 0.355 |
8 | 8 | 0.931 |
80 | 80 | 0.00414 |
81 | 81 | 0.438 |
82 | 82 | 0.275 |
83 | 83 | 0.197 |
84 | 84 | 0.229 |
85 | 85 | 0.257 |
86 | 86 | 0.655 |
87 | 87 | 0.217 |
88 | 88 | 0.523 |
89 | 89 | 0.645 |
9 | 9 | 0.0378 |
90 | 90 | 0.37 |
91 | 91 | 0.0857 |
92 | 92 | 0.0887 |
93 | 93 | 0.989 |
94 | 94 | 0.134 |
95 | 95 | 0.791 |
96 | 96 | 0.582 |
97 | 97 | 0.469 |
98 | 98 | 0.602 |
99 | 99 | 0.768 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13061
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0102424 mesothelioma cell line sample
FF:0103764 NCI cell sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0002320 (connective tissue cell)
0000066 (epithelial cell)
0002371 (somatic cell)
0000076 (squamous epithelial cell)
0000213 (lining cell)
0000215 (barrier cell)
0000255 (eukaryotic cell)
0000057 (fibroblast)
0000077 (mesothelial cell)
DOID: Disease
4 (disease)
162 (cancer)
14566 (disease of cellular proliferation)
0050687 (cell type cancer)
1115 (sarcoma)
UBERON: Anatomy
0002384 (connective tissue)
0000479 (tissue)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0001062 (anatomical entity)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100453 (fibroblast cell line sample)
0100400 (sarcoma cell line sample)
0100460 (fibrosarcoma cell line sample)
0102424 (mesothelioma cell line sample)
0103764 (NCI cell sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)
CL:0000222 (mesodermal cell)