FF:10514-107E1: Difference between revisions
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{{f5samples | {{f5samples | ||
|ancestors_in_anatomy_facet=UBERON: | |DRA_sample_Accession=CAGE@SAMD00005005 | ||
|accession_numbers=CAGE;DRX007930;DRR008802;DRZ000227;DRZ001612;DRZ011577;DRZ012962 | |||
|ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0001003,UBERON:0002097,UBERON:0002199,UBERON:0000483,UBERON:0000479,UBERON:0004121,UBERON:0000062,UBERON:0000061,UBERON:0000465,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0000119,UBERON:0003102,UBERON:0007376,UBERON:0010371,UBERON:0010317,UBERON:0002416 | |||
|ancestors_in_cell_lineage_facet= | |ancestors_in_cell_lineage_facet= | ||
|ancestors_in_disease_facet=DOID:4,DOID: | |ancestors_in_disease_facet=DOID:4,DOID:162,DOID:14566,DOID:0050687,DOID:1909 | ||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100849 | |||
|comment= | |comment= | ||
|created_by= | |created_by= | ||
|creation_date= | |creation_date= | ||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |def= | ||
|expression_enrichment_score | |||
|fonse_cell_line=FF:0100849 | |fonse_cell_line=FF:0100849 | ||
|fonse_cell_line_closure=FF:0100849 | |fonse_cell_line_closure=FF:0100849 | ||
| Line 35: | Line 41: | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/melanoma%2520cell%2520line%253aCOLO%2520679.CNhs11281.10514-107E1.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/melanoma%2520cell%2520line%253aCOLO%2520679.CNhs11281.10514-107E1.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/melanoma%2520cell%2520line%253aCOLO%2520679.CNhs11281.10514-107E1.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/melanoma%2520cell%2520line%253aCOLO%2520679.CNhs11281.10514-107E1.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/melanoma%2520cell%2520line%253aCOLO%2520679.CNhs11281.10514-107E1.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10514-107E1 | |id=FF:10514-107E1 | ||
|is_a=EFO:0002091;;FF: | |is_a=EFO:0002091;;FF:0000210;;FF:0100849 | ||
|is_obsolete= | |||
|library_id=CNhs11281 | |||
|library_id_phase_based=2:CNhs11281 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10514 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10514 | |||
|name=melanoma cell line:COLO 679 | |name=melanoma cell line:COLO 679 | ||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
| Line 42: | Line 60: | ||
|profile_cagescan=,,, | |profile_cagescan=,,, | ||
|profile_hcage=CNhs11281,LSID759,release008,COMPLETED | |profile_hcage=CNhs11281,LSID759,release008,COMPLETED | ||
|profile_rnaseq= | |profile_rnaseq= | ||
|profile_srnaseq=,,, | |profile_srnaseq=,,, | ||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,-0.0452742229459078,0,-0.216041953043388,-0.282403560576942,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.153323010348428,0,0,0,0,0,-0.0979578962680575,0,0,-0.132956589778862,0,0,0,0,0,0,0,0,0,0,0,0,-0.075897361118605,0,0,0,0,0,0,0,0,-0.0242150211128343,0,0,0,0,0,-0.00222588796219081,0,0.108914447202747,0,0,0.108563181232255,0,0,0,0,0,0,0,0,0.162847278629043,0,0,0,0,0.115043807140478,0,0,0,0,0.0306600895750632,0,0,0,0,0,-0.108715035659486,0,0,0,-0.00180279844726638,0.025285972390485,0,0,0.0306600895750632,0,0.147044184993411,-0.138477200800895,0,0,0,0.0613201791501264,0,0,0,0,0,0,0,0,0,0,0,0,0,0.116730736776201,0.0613201791501264,0,0,-0.0727088341078527,-0.145763388870799,0,0,0,0,0,0 | |||
|repeat_enrich_byname=0,0,0,0,0.147044184993411,0.115043807140478,0,0.205906808445352,0,0,0,0,0,0,0,0,-0.247178875285564,0,-0.159893647601894,-0.0284713353829936,0,0,0.0292262162194151,0,0.0613201791501264,0,0,0,0,0,0.115043807140478,0,0.0347274116764782,0,0.0109076275608115,0,0,0,0,-0.0128900110122785,0.28350869995469,0,0.0126430091286391,-0.0683442610773682,0,0,0,0,0.326164104570612,0,-0.120879483793741,-0.0213999891732909,0.808114956744084,-0.346077503677804,0.0682391482480983,0,0,0.057521903570239,-0.238270923115029,0.313506344900385,0,0,-0.121779851751874,0.0659424676080705,0,0,-0.391044581551635,0,0.12823663779341,-0.145914646159577,0,0.0306600895750632,0,0,0,0,0,0,0,0,0.115043807140478,0,0,-0.0574934668214365,0.207847675087398,0,0,0,0,-0.264090472701892,0,0,-0.0590935848064525,-0.25387024213272,-0.0571136536880675,0.246068579926731,0,-0.302389727009913,0.142268941071619,-0.555502104805946,-0.00180279844726638,-0.147401849371139,0.0910277051903047,0,-0.331975643481629,0.0239174141146615,-0.0888562402216181,-0.0531051122505828,-0.0437646835759722,-0.431536162560846,-0.150962911277293,0.0613201791501264,0.115043807140478,0,-0.193471736285624,0,0,0.147002661676382,-0.00290728884789831,0.436231914110232,-0.182566295605253,0.0610578424410065,-0.00550765356490746,-0.00887243888160735,-0.251529644451243,0,0.137454637342089,0,0,-0.0152793222556979,-0.0511541451339083,-0.385116695312629,0.140134210563357,0,-0.169784890660866,-0.00702408192724182,0.113736943939811,-0.0879910353609219,-0.158695752203458,0,0.0613201791501264,0.0732688148723643,0,0.0613201791501264,0,0.000277770408229784,0,0.207566318141769,-0.194472866803086,0.112163714671536,0,-0.068317887622971,0.00525073530898155,-0.011450054876684,0,-0.149964864986476,0.0788386631293465,-0.12283347366346,-0.0720754823484449,0,-0.0510217044650055,-0.107680938095016,-0.1012349682395,0.05057194478097,0.0028733523383012,0.0254884499663053,0.0700904746867279,0.154914390338153,0.144671714579463,0.027050693089913,-0.0881268324752877,0,0.277726541874935,-0.144661859855158,-0.0738605890119886,-0.403468232543774,0,0.155992720061423,0,0.300998627753921,0,-0.213487573391741,-0.0252573561277573,0.380978922284237,0.0335589181545755,0,-0.0886292943500196,-0.726810758623848,0,-0.0744029646966556,0,0,-0.089046904184513,-0.108715035659486,0.211734017499913,0.0214858511137205,0,-0.339863483145817,0,0,0.145315339115093,-0.174155858614262,0,0.177245485126476,-0.0555583299512207,-0.050571456933119,-0.0546508942848077,0.0613201791501264,0,-0.645700337992725,0,0,0.113914733819135,0,0.343487401618817,-0.253326341486756,-0.122118378054933,-0.0779627198791925,0,0,-0.0624839588246974,0,0.232605707013132,0,0,0.531611959006756,0,0,0.122539768115559,0,0,0,0,0,0,0,0,0,0.184909883014644,0.0953833450273913,0,0.0873330451696321,0,0.205906808445352,0,0,0,0,0,0,0.0985097366867502,0.00926167989639825,0.327199259567419,0,0,0,0,0.405933814065219,-0.0403892834656809,0,0.14914671824252,0,0,0,0,-0.024820810639085,0,0,0,0.0306600895750632,0.0573133500868143,-0.206587677405984,0,0,0,-0.27695440160179,0,0,0,0,0.00771552889951099,0,0,0,0,-0.276601010633502,-0.0815818795468414,0,-0.274104421851323,-0.86180888122904,0.196723243503252,0,0,-0.146303324649409,0,0.162847278629043,0.0722359974236069,0,0,0.0198970447883852,0,0,0,0,0,0.0613201791501264,-0.0514672337707128,0,0,0,0,0,0.0613201791501264,0,0,0,0,0.115043807140478,-0.151874365727072,-0.030903877508384,0,0,0,0,0,0,0,0.0334158804913361,0.201878607118134,0,0,0,0,0,0.162847278629043,0,0,0.117554991189855,0,0,0,0,0,0.108914447202747,0,0.0613201791501264,0,0,-0.564807121153884,0,0,-0.216041953043388,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0619989068853213,-0.299459911436,0,0.0613201791501264,0,0,0,0,0,-0.213513119055964,0,0,0,0,-0.0525641945588508,0,0,0,0.269005755767141,0,-0.0452742229459078,0,0,0,0,0,0.0613201791501264,0.102953404222676,0,0,0,0,0,0,0.0613201791501264,0,0,0,0,0,0,0,-0.243287570279399,0.248757083890311,-0.124360237343867,0,0,0,-0.0921236402629655,0,0,0,0,0,0,0.0261814795417121,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0613201791501264,0,0,0,0,0,0,0.0838357003957947,0,0,0,0,0,0,0,-0.0979578962680575,0.115043807140478,0,0.041580683997213,0,0,0,0,0,0,-0.0748725099580475,-0.00526822407935435,0.0054724470199242,0,0,0,-0.0237254829073918,0,0,-0.0394212835279458,0,0.214232037321251,0.0613201791501264,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.153323010348428,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0613201791501264,0,0.281009424740152,0.0306600895750632,0,0,0.0613201791501264,0,0,0,0.0541706298698857,0,0,0.0613201791501264,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.115043807140478,-0.0800184682686384,0,0,0,0.101106341493071,0,0,0,0,0,0,0.115043807140478,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0912362958002803,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0482220752390542,0,-0.0230564530799007,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0211680084360928,0,0,0,0,-0.0476371106609188,0,0,0,0,0,0,0,0.053076214568223,0,0,0.0613201791501264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| |||
|rna_box=107 | |rna_box=107 | ||
|rna_catalog_number= | |rna_catalog_number= | ||
| Line 54: | Line 75: | ||
|rna_rin= | |rna_rin= | ||
|rna_sample_type=total RNA | |rna_sample_type=total RNA | ||
|rna_tube_id= | |rna_tube_id=1.07E+03 | ||
|rna_weight_ug=62.37925 | |rna_weight_ug=62.37925 | ||
|sample_age=47 | |sample_age=47 | ||
|sample_category=cell lines | |||
|sample_cell_catalog=RCB0989 | |sample_cell_catalog=RCB0989 | ||
|sample_cell_line=COLO 679 | |sample_cell_line=COLO 679 | ||
| Line 69: | Line 91: | ||
|sample_ethnicity=unknown | |sample_ethnicity=unknown | ||
|sample_experimental_condition= | |sample_experimental_condition= | ||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.07810743422543e-271!GO:0043231;intracellular membrane-bound organelle;3.71256399810147e-225!GO:0043226;organelle;4.33792750058282e-225!GO:0043227;membrane-bound organelle;4.33792750058282e-225!GO:0043229;intracellular organelle;1.51402163349484e-224!GO:0005737;cytoplasm;3.2869383528691e-203!GO:0044422;organelle part;1.06776587580741e-161!GO:0044446;intracellular organelle part;2.68306716876363e-160!GO:0044444;cytoplasmic part;6.3230272258708e-152!GO:0032991;macromolecular complex;4.9357306449507e-112!GO:0044237;cellular metabolic process;4.12363207889491e-102!GO:0044238;primary metabolic process;1.25960799556321e-100!GO:0043170;macromolecule metabolic process;3.67321628957999e-90!GO:0030529;ribonucleoprotein complex;9.2629018981212e-89!GO:0005634;nucleus;8.30466525487384e-87!GO:0005739;mitochondrion;3.16175400814791e-84!GO:0043233;organelle lumen;4.02767770844147e-84!GO:0031974;membrane-enclosed lumen;4.02767770844147e-84!GO:0003723;RNA binding;3.38510158377957e-78!GO:0044428;nuclear part;1.2325019616659e-77!GO:0005515;protein binding;4.70176290052465e-66!GO:0043234;protein complex;6.38397317204709e-59!GO:0044429;mitochondrial part;1.78779905274901e-57!GO:0031090;organelle membrane;1.45899890722038e-56!GO:0006396;RNA processing;2.24315047797871e-53!GO:0043283;biopolymer metabolic process;2.94163836489151e-53!GO:0006412;translation;2.94163836489151e-53!GO:0005840;ribosome;2.99821695502091e-53!GO:0033036;macromolecule localization;2.82576475139987e-51!GO:0015031;protein transport;4.37401551336263e-51!GO:0016043;cellular component organization and biogenesis;4.37401551336263e-51!GO:0019538;protein metabolic process;6.42069210790515e-50!GO:0031967;organelle envelope;1.57112003061943e-49!GO:0031975;envelope;4.40907886185285e-49!GO:0009058;biosynthetic process;6.66512456819462e-48!GO:0008104;protein localization;7.71788304970539e-47!GO:0031981;nuclear lumen;7.71788304970539e-47!GO:0045184;establishment of protein localization;2.10881524776333e-46!GO:0044249;cellular biosynthetic process;3.59445764752963e-46!GO:0003735;structural constituent of ribosome;1.08234237648847e-45!GO:0010467;gene expression;1.30400643125922e-45!GO:0044260;cellular macromolecule metabolic process;7.34194529315365e-45!GO:0044267;cellular protein metabolic process;2.405724553927e-44!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.9636467798839e-43!GO:0009059;macromolecule biosynthetic process;3.00703376087516e-42!GO:0046907;intracellular transport;1.57498794473735e-41!GO:0033279;ribosomal subunit;8.26654262924866e-40!GO:0006996;organelle organization and biogenesis;1.21969328879172e-39!GO:0016071;mRNA metabolic process;5.32891262565527e-39!GO:0005829;cytosol;2.86930952758768e-37!GO:0005740;mitochondrial envelope;1.49984202622391e-35!GO:0043228;non-membrane-bound organelle;1.98620646525693e-35!GO:0043232;intracellular non-membrane-bound organelle;1.98620646525693e-35!GO:0008380;RNA splicing;2.297596326586e-35!GO:0006886;intracellular protein transport;3.85726574598428e-35!GO:0019866;organelle inner membrane;2.45818495050668e-34!GO:0065003;macromolecular complex assembly;3.53418767952617e-34!GO:0031966;mitochondrial membrane;8.57447478796298e-34!GO:0006397;mRNA processing;3.15360460215734e-33!GO:0005743;mitochondrial inner membrane;1.16831304634032e-32!GO:0022613;ribonucleoprotein complex biogenesis and assembly;2.40291240212488e-32!GO:0003676;nucleic acid binding;4.60224480554749e-32!GO:0022607;cellular component assembly;7.45426165995009e-31!GO:0048770;pigment granule;9.06970321935432e-31!GO:0042470;melanosome;9.06970321935432e-31!GO:0006259;DNA metabolic process;6.39245578175471e-30!GO:0000166;nucleotide binding;2.64002860849497e-29!GO:0005654;nucleoplasm;3.22841915417267e-29!GO:0051649;establishment of cellular localization;3.06763766314659e-28!GO:0051641;cellular localization;2.63117088982865e-27!GO:0005830;cytosolic ribosome (sensu Eukaryota);4.28652281636367e-27!GO:0031980;mitochondrial lumen;7.16805425014976e-27!GO:0005759;mitochondrial matrix;7.16805425014976e-27!GO:0007049;cell cycle;2.34904015423872e-26!GO:0006119;oxidative phosphorylation;4.70368074664626e-26!GO:0005681;spliceosome;4.70368074664626e-26!GO:0044455;mitochondrial membrane part;7.5575905919059e-25!GO:0044451;nucleoplasm part;9.68553155004636e-24!GO:0016462;pyrophosphatase activity;1.52355290087884e-22!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;2.06082739039369e-22!GO:0016817;hydrolase activity, acting on acid anhydrides;2.46633352354315e-22!GO:0012505;endomembrane system;4.57132439575972e-22!GO:0044445;cytosolic part;6.24048100322994e-22!GO:0017111;nucleoside-triphosphatase activity;1.39890352639223e-21!GO:0016070;RNA metabolic process;1.71240699654762e-21!GO:0016874;ligase activity;2.86676304537533e-21!GO:0015935;small ribosomal subunit;4.92418413596184e-21!GO:0032553;ribonucleotide binding;8.98509687166939e-21!GO:0032555;purine ribonucleotide binding;8.98509687166939e-21!GO:0017076;purine nucleotide binding;1.77509429539395e-20!GO:0022402;cell cycle process;3.95789789875779e-20!GO:0006512;ubiquitin cycle;6.15114365881592e-20!GO:0015934;large ribosomal subunit;8.13412970852591e-20!GO:0006457;protein folding;9.77382329127623e-20!GO:0044265;cellular macromolecule catabolic process;4.76559430516772e-19!GO:0000278;mitotic cell cycle;5.89744357051758e-19!GO:0005746;mitochondrial respiratory chain;6.67268325287828e-19!GO:0005730;nucleolus;8.42204646514453e-19!GO:0022618;protein-RNA complex assembly;1.43176056221064e-18!GO:0051186;cofactor metabolic process;3.00774012554836e-18!GO:0005783;endoplasmic reticulum;1.09056628144558e-17!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;1.10773032270996e-17!GO:0006605;protein targeting;1.15450019933787e-17!GO:0032559;adenyl ribonucleotide binding;1.81478931963821e-17!GO:0051603;proteolysis involved in cellular protein catabolic process;2.01252629019014e-17!GO:0019941;modification-dependent protein catabolic process;2.24864629981406e-17!GO:0043632;modification-dependent macromolecule catabolic process;2.24864629981406e-17!GO:0006511;ubiquitin-dependent protein catabolic process;2.55244161693491e-17!GO:0005524;ATP binding;2.95755970392932e-17!GO:0044257;cellular protein catabolic process;3.84833269912656e-17!GO:0044248;cellular catabolic process;4.65993897866497e-17!GO:0030554;adenyl nucleotide binding;4.78862123839841e-17!GO:0043285;biopolymer catabolic process;5.21403660597555e-17!GO:0005694;chromosome;9.075858172826e-17!GO:0050136;NADH dehydrogenase (quinone) activity;1.05211682277788e-16!GO:0003954;NADH dehydrogenase activity;1.05211682277788e-16!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.05211682277788e-16!GO:0005761;mitochondrial ribosome;1.12687305594036e-16!GO:0000313;organellar ribosome;1.12687305594036e-16!GO:0008135;translation factor activity, nucleic acid binding;2.36143893679051e-16!GO:0009057;macromolecule catabolic process;2.38050746342548e-16!GO:0000087;M phase of mitotic cell cycle;2.51844139514781e-16!GO:0007067;mitosis;6.72138326593168e-16!GO:0043412;biopolymer modification;9.74479555992021e-16!GO:0051276;chromosome organization and biogenesis;1.06592312584495e-15!GO:0006974;response to DNA damage stimulus;1.21772929888013e-15!GO:0008134;transcription factor binding;1.49201914620228e-15!GO:0006732;coenzyme metabolic process;1.86272749452823e-15!GO:0042775;organelle ATP synthesis coupled electron transport;4.70106277670561e-15!GO:0042773;ATP synthesis coupled electron transport;4.70106277670561e-15!GO:0044427;chromosomal part;1.01884497329784e-14!GO:0030964;NADH dehydrogenase complex (quinone);1.13795365367238e-14!GO:0045271;respiratory chain complex I;1.13795365367238e-14!GO:0005747;mitochondrial respiratory chain complex I;1.13795365367238e-14!GO:0044432;endoplasmic reticulum part;1.35917433908384e-14!GO:0000502;proteasome complex (sensu Eukaryota);1.36209038596302e-14!GO:0030163;protein catabolic process;1.43187625414644e-14!GO:0005635;nuclear envelope;1.54031731569394e-14!GO:0042254;ribosome biogenesis and assembly;1.65446877181997e-14!GO:0051082;unfolded protein binding;3.11255202237083e-14!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;3.2247658926275e-14!GO:0016887;ATPase activity;3.369562289128e-14!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);3.86457891570655e-14!GO:0051301;cell division;4.97295130225067e-14!GO:0022403;cell cycle phase;7.83809783593871e-14!GO:0042623;ATPase activity, coupled;8.54028134070426e-14!GO:0031965;nuclear membrane;8.60082673248915e-14!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.01060049905272e-13!GO:0006464;protein modification process;1.21838873033374e-13!GO:0005794;Golgi apparatus;1.51229679602015e-13!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.53898323765116e-13!GO:0006399;tRNA metabolic process;4.65008794685358e-13!GO:0006281;DNA repair;5.34874620675145e-13!GO:0006366;transcription from RNA polymerase II promoter;6.9932499356573e-13!GO:0000279;M phase;7.21844843892878e-13!GO:0006325;establishment and/or maintenance of chromatin architecture;1.21624558072239e-12!GO:0003743;translation initiation factor activity;2.36333145897002e-12!GO:0000398;nuclear mRNA splicing, via spliceosome;2.63909742069669e-12!GO:0000375;RNA splicing, via transesterification reactions;2.63909742069669e-12!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;2.63909742069669e-12!GO:0044453;nuclear membrane part;3.0555774776842e-12!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;3.09792660972305e-12!GO:0006323;DNA packaging;4.43014204312877e-12!GO:0048193;Golgi vesicle transport;4.73705757792703e-12!GO:0006413;translational initiation;7.24144749980289e-12!GO:0006913;nucleocytoplasmic transport;9.67562546109458e-12!GO:0016192;vesicle-mediated transport;1.05336455062095e-11!GO:0051726;regulation of cell cycle;1.74439789954793e-11!GO:0051169;nuclear transport;1.79401463697193e-11!GO:0043687;post-translational protein modification;2.06798897442122e-11!GO:0000074;regulation of progression through cell cycle;3.1759397878574e-11!GO:0006446;regulation of translational initiation;3.1953674704592e-11!GO:0008565;protein transporter activity;3.45005106998974e-11!GO:0008639;small protein conjugating enzyme activity;3.45786371231618e-11!GO:0006403;RNA localization;4.30131983008344e-11!GO:0050657;nucleic acid transport;4.44866361723385e-11!GO:0051236;establishment of RNA localization;4.44866361723385e-11!GO:0050658;RNA transport;4.44866361723385e-11!GO:0007005;mitochondrion organization and biogenesis;4.88023417410727e-11!GO:0045333;cellular respiration;5.22989975592854e-11!GO:0004386;helicase activity;5.36262820083211e-11!GO:0042175;nuclear envelope-endoplasmic reticulum network;5.84935497331433e-11!GO:0065002;intracellular protein transport across a membrane;6.15879814503869e-11!GO:0006260;DNA replication;6.63859003584086e-11!GO:0009056;catabolic process;7.11727368962003e-11!GO:0004842;ubiquitin-protein ligase activity;7.58325822794303e-11!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;8.53791771712238e-11!GO:0006461;protein complex assembly;8.72827886637648e-11!GO:0003712;transcription cofactor activity;9.47397556017421e-11!GO:0051188;cofactor biosynthetic process;1.05130592304721e-10!GO:0005643;nuclear pore;1.10071142388356e-10!GO:0006163;purine nucleotide metabolic process;1.12309467617541e-10!GO:0005789;endoplasmic reticulum membrane;1.43315422385733e-10!GO:0009259;ribonucleotide metabolic process;1.5138705076165e-10!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.6614826261315e-10!GO:0019787;small conjugating protein ligase activity;1.87599433902082e-10!GO:0009060;aerobic respiration;2.56808343191405e-10!GO:0016604;nuclear body;2.86109635480581e-10!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;2.99536505987982e-10!GO:0004812;aminoacyl-tRNA ligase activity;2.99536505987982e-10!GO:0016875;ligase activity, forming carbon-oxygen bonds;2.99536505987982e-10!GO:0015630;microtubule cytoskeleton;3.63699307164522e-10!GO:0015986;ATP synthesis coupled proton transport;3.69643149885923e-10!GO:0015985;energy coupled proton transport, down electrochemical gradient;3.69643149885923e-10!GO:0009150;purine ribonucleotide metabolic process;4.04181123110813e-10!GO:0006164;purine nucleotide biosynthetic process;5.89729227395078e-10!GO:0043038;amino acid activation;6.04239369014145e-10!GO:0006418;tRNA aminoacylation for protein translation;6.04239369014145e-10!GO:0043039;tRNA aminoacylation;6.04239369014145e-10!GO:0009719;response to endogenous stimulus;6.62207429022351e-10!GO:0015078;hydrogen ion transmembrane transporter activity;7.24038904347064e-10!GO:0009055;electron carrier activity;8.84809295443351e-10!GO:0005768;endosome;1.00173073013431e-09!GO:0019829;cation-transporting ATPase activity;1.32027435502977e-09!GO:0009199;ribonucleoside triphosphate metabolic process;1.5248487080569e-09!GO:0009260;ribonucleotide biosynthetic process;1.67034755259282e-09!GO:0006364;rRNA processing;1.70163574272678e-09!GO:0008026;ATP-dependent helicase activity;2.02070766355785e-09!GO:0009152;purine ribonucleotide biosynthetic process;2.06369101722298e-09!GO:0006099;tricarboxylic acid cycle;2.2209039480647e-09!GO:0046356;acetyl-CoA catabolic process;2.2209039480647e-09!GO:0016469;proton-transporting two-sector ATPase complex;2.33280519271741e-09!GO:0009205;purine ribonucleoside triphosphate metabolic process;2.69114166744663e-09!GO:0009144;purine nucleoside triphosphate metabolic process;2.69114166744663e-09!GO:0016607;nuclear speck;3.26323467481962e-09!GO:0009141;nucleoside triphosphate metabolic process;3.40222711238901e-09!GO:0005773;vacuole;3.80102665017754e-09!GO:0016072;rRNA metabolic process;4.02666025525594e-09!GO:0051028;mRNA transport;4.11415993048872e-09!GO:0006084;acetyl-CoA metabolic process;4.41866618667814e-09!GO:0012501;programmed cell death;4.55130892759295e-09!GO:0046034;ATP metabolic process;4.6434821153223e-09!GO:0009108;coenzyme biosynthetic process;4.64580062851999e-09!GO:0009142;nucleoside triphosphate biosynthetic process;4.70777306704129e-09!GO:0009201;ribonucleoside triphosphate biosynthetic process;4.70777306704129e-09!GO:0046930;pore complex;4.71644195720152e-09!GO:0006915;apoptosis;4.78350932105923e-09!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;5.32871704410322e-09!GO:0065004;protein-DNA complex assembly;6.80944070529153e-09!GO:0017038;protein import;6.8260055984579e-09!GO:0000785;chromatin;7.05208054821153e-09!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;7.25657630306111e-09!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;7.28023006296969e-09!GO:0016881;acid-amino acid ligase activity;7.57343198168307e-09!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;8.56501815511651e-09!GO:0009145;purine nucleoside triphosphate biosynthetic process;8.56501815511651e-09!GO:0006333;chromatin assembly or disassembly;9.04200925464611e-09!GO:0006754;ATP biosynthetic process;1.03566101211334e-08!GO:0006753;nucleoside phosphate metabolic process;1.03566101211334e-08!GO:0031982;vesicle;1.71756545078248e-08!GO:0016568;chromatin modification;1.90355733112986e-08!GO:0031988;membrane-bound vesicle;2.31696624053352e-08!GO:0050794;regulation of cellular process;2.55441055495361e-08!GO:0005793;ER-Golgi intermediate compartment;2.7908951808551e-08!GO:0031410;cytoplasmic vesicle;2.86909518246017e-08!GO:0009109;coenzyme catabolic process;2.89718994833878e-08!GO:0016023;cytoplasmic membrane-bound vesicle;3.50525389742944e-08!GO:0000323;lytic vacuole;4.67501965741777e-08!GO:0005764;lysosome;4.67501965741777e-08!GO:0008219;cell death;4.7547709498625e-08!GO:0016265;death;4.7547709498625e-08!GO:0032446;protein modification by small protein conjugation;4.94169912865984e-08!GO:0005667;transcription factor complex;5.99769264480637e-08!GO:0008654;phospholipid biosynthetic process;6.05766492031169e-08!GO:0016567;protein ubiquitination;7.21787886157423e-08!GO:0030532;small nuclear ribonucleoprotein complex;8.5536598306275e-08!GO:0009117;nucleotide metabolic process;9.20151470941911e-08!GO:0016740;transferase activity;1.2708577968406e-07!GO:0015077;monovalent inorganic cation transmembrane transporter activity;1.74477987091772e-07!GO:0016779;nucleotidyltransferase activity;2.07684981552451e-07!GO:0005813;centrosome;2.8406001808896e-07!GO:0005798;Golgi-associated vesicle;3.06856740553141e-07!GO:0051187;cofactor catabolic process;3.11389932721278e-07!GO:0043623;cellular protein complex assembly;3.26404288508661e-07!GO:0016563;transcription activator activity;3.2832881920444e-07!GO:0005819;spindle;3.81799982473552e-07!GO:0006752;group transfer coenzyme metabolic process;3.83506952445866e-07!GO:0048523;negative regulation of cellular process;4.37225442508831e-07!GO:0051246;regulation of protein metabolic process;4.51464987035178e-07!GO:0016787;hydrolase activity;5.08490713201511e-07!GO:0043566;structure-specific DNA binding;5.16645492921942e-07!GO:0016853;isomerase activity;5.53043851326233e-07!GO:0005770;late endosome;5.55923878932981e-07!GO:0005815;microtubule organizing center;5.84331081320729e-07!GO:0048475;coated membrane;6.26548361722228e-07!GO:0030117;membrane coat;6.26548361722228e-07!GO:0045259;proton-transporting ATP synthase complex;7.29696024788543e-07!GO:0015980;energy derivation by oxidation of organic compounds;7.68885751582489e-07!GO:0006888;ER to Golgi vesicle-mediated transport;8.52048738366157e-07!GO:0045786;negative regulation of progression through cell cycle;1.19144262286724e-06!GO:0030120;vesicle coat;1.20384849334753e-06!GO:0030662;coated vesicle membrane;1.20384849334753e-06!GO:0006793;phosphorus metabolic process;1.24096218086084e-06!GO:0006796;phosphate metabolic process;1.24096218086084e-06!GO:0000151;ubiquitin ligase complex;1.57372977909567e-06!GO:0003697;single-stranded DNA binding;1.86672576846997e-06!GO:0016491;oxidoreductase activity;2.08860869137981e-06!GO:0044440;endosomal part;2.4206494065884e-06!GO:0010008;endosome membrane;2.4206494065884e-06!GO:0019899;enzyme binding;2.59318346150142e-06!GO:0006357;regulation of transcription from RNA polymerase II promoter;2.77830966092484e-06!GO:0003713;transcription coactivator activity;2.92520994548042e-06!GO:0006334;nucleosome assembly;2.93314259345124e-06!GO:0000245;spliceosome assembly;3.02343057923111e-06!GO:0051170;nuclear import;3.73689282385914e-06!GO:0046474;glycerophospholipid biosynthetic process;4.07289738121999e-06!GO:0044431;Golgi apparatus part;4.12409695318982e-06!GO:0000314;organellar small ribosomal subunit;4.35145738933639e-06!GO:0005763;mitochondrial small ribosomal subunit;4.35145738933639e-06!GO:0031497;chromatin assembly;4.43022186501857e-06!GO:0003924;GTPase activity;4.50754883492962e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;5.59042791121144e-06!GO:0005788;endoplasmic reticulum lumen;5.95990856148207e-06!GO:0005839;proteasome core complex (sensu Eukaryota);6.73730224897673e-06!GO:0006091;generation of precursor metabolites and energy;7.82546388624266e-06!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;1.03889866492369e-05!GO:0006626;protein targeting to mitochondrion;1.06021322741993e-05!GO:0006606;protein import into nucleus;1.06374873654576e-05!GO:0031252;leading edge;1.09790001226806e-05!GO:0048519;negative regulation of biological process;1.14745967418401e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;1.21095584793663e-05!GO:0006613;cotranslational protein targeting to membrane;1.27632534607375e-05!GO:0006916;anti-apoptosis;1.27632534607375e-05!GO:0007051;spindle organization and biogenesis;1.27632534607375e-05!GO:0006839;mitochondrial transport;1.31246225883159e-05!GO:0003899;DNA-directed RNA polymerase activity;1.4285999445125e-05!GO:0000775;chromosome, pericentric region;1.56016237177866e-05!GO:0051168;nuclear export;1.71328898299702e-05!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;1.85591987179189e-05!GO:0015399;primary active transmembrane transporter activity;1.85591987179189e-05!GO:0042981;regulation of apoptosis;1.88589752090677e-05!GO:0005762;mitochondrial large ribosomal subunit;1.92390959479289e-05!GO:0000315;organellar large ribosomal subunit;1.92390959479289e-05!GO:0016564;transcription repressor activity;2.22248301153725e-05!GO:0005525;GTP binding;2.65753595666297e-05!GO:0004298;threonine endopeptidase activity;2.82805764083053e-05!GO:0003724;RNA helicase activity;2.88586569983473e-05!GO:0043067;regulation of programmed cell death;2.88586569983473e-05!GO:0043069;negative regulation of programmed cell death;3.43911929058338e-05!GO:0006261;DNA-dependent DNA replication;3.78055355467236e-05!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;3.78055355467236e-05!GO:0043021;ribonucleoprotein binding;3.87033210378623e-05!GO:0043066;negative regulation of apoptosis;3.87426494885576e-05!GO:0050789;regulation of biological process;3.87426494885576e-05!GO:0046467;membrane lipid biosynthetic process;4.10501633639368e-05!GO:0016310;phosphorylation;4.33191731377893e-05!GO:0030659;cytoplasmic vesicle membrane;4.49314861894235e-05!GO:0046489;phosphoinositide biosynthetic process;4.75734770938439e-05!GO:0019752;carboxylic acid metabolic process;4.8978018531473e-05!GO:0031324;negative regulation of cellular metabolic process;5.41922947759368e-05!GO:0019222;regulation of metabolic process;5.67390214790047e-05!GO:0051329;interphase of mitotic cell cycle;5.81707337577348e-05!GO:0006082;organic acid metabolic process;5.98851550908809e-05!GO:0030880;RNA polymerase complex;6.00183461921437e-05!GO:0048471;perinuclear region of cytoplasm;6.33914680815024e-05!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;6.34830958341776e-05!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;6.43764563518663e-05!GO:0045454;cell redox homeostasis;6.69848506030356e-05!GO:0006383;transcription from RNA polymerase III promoter;6.95996415668977e-05!GO:0009165;nucleotide biosynthetic process;7.3627323556882e-05!GO:0016859;cis-trans isomerase activity;7.59250504279958e-05!GO:0003714;transcription corepressor activity;7.69090011883388e-05!GO:0030867;rough endoplasmic reticulum membrane;8.70481379114883e-05!GO:0008033;tRNA processing;9.22255271335348e-05!GO:0042802;identical protein binding;9.41613879884208e-05!GO:0009892;negative regulation of metabolic process;0.00011521464976669!GO:0003682;chromatin binding;0.000116115117191901!GO:0043681;protein import into mitochondrion;0.000120503454687593!GO:0006612;protein targeting to membrane;0.000122294703727615!GO:0012506;vesicle membrane;0.000123867942940294!GO:0044433;cytoplasmic vesicle part;0.000139783396584915!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.000149760407284444!GO:0000428;DNA-directed RNA polymerase complex;0.000149760407284444!GO:0007006;mitochondrial membrane organization and biogenesis;0.000149760407284444!GO:0006650;glycerophospholipid metabolic process;0.000156156708390806!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000165516476955897!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000183532076223317!GO:0051427;hormone receptor binding;0.00018686147773655!GO:0032561;guanyl ribonucleotide binding;0.000199766844040792!GO:0019001;guanyl nucleotide binding;0.000199766844040792!GO:0022890;inorganic cation transmembrane transporter activity;0.000201886515697966!GO:0019867;outer membrane;0.000210362180744137!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000227489772991931!GO:0007088;regulation of mitosis;0.000263933686694959!GO:0044452;nucleolar part;0.000263933686694959!GO:0016251;general RNA polymerase II transcription factor activity;0.000266574062074326!GO:0015631;tubulin binding;0.000271880498710804!GO:0043492;ATPase activity, coupled to movement of substances;0.000274552616538044!GO:0005769;early endosome;0.00027570273471673!GO:0031968;organelle outer membrane;0.000277250794246539!GO:0006414;translational elongation;0.000277250794246539!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000277497958359169!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000305840259999944!GO:0046148;pigment biosynthetic process;0.000309049385605026!GO:0006818;hydrogen transport;0.000318924082939255!GO:0006520;amino acid metabolic process;0.000320974638803726!GO:0051325;interphase;0.000332337064945245!GO:0003690;double-stranded DNA binding;0.000334409800353499!GO:0000075;cell cycle checkpoint;0.000337371320221835!GO:0006402;mRNA catabolic process;0.000348409782889912!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000353037542404604!GO:0035257;nuclear hormone receptor binding;0.000362042794586504!GO:0008250;oligosaccharyl transferase complex;0.000405831034339335!GO:0015992;proton transport;0.000406847726090028!GO:0051789;response to protein stimulus;0.000411022317714559!GO:0006986;response to unfolded protein;0.000411022317714559!GO:0005885;Arp2/3 protein complex;0.000430558915391168!GO:0007010;cytoskeleton organization and biogenesis;0.000473686956456521!GO:0005874;microtubule;0.000475749828079606!GO:0007034;vacuolar transport;0.000484630013086896!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000495612884841785!GO:0003729;mRNA binding;0.000519928161361445!GO:0007093;mitotic cell cycle checkpoint;0.00053480913035651!GO:0000139;Golgi membrane;0.000543757196823663!GO:0000049;tRNA binding;0.000555151150889761!GO:0004576;oligosaccharyl transferase activity;0.000581417781023895!GO:0050662;coenzyme binding;0.000595851295888647!GO:0005048;signal sequence binding;0.000606967910132464!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.000606967910132464!GO:0044262;cellular carbohydrate metabolic process;0.000645712438330893!GO:0005741;mitochondrial outer membrane;0.000669555274380672!GO:0016481;negative regulation of transcription;0.000681135953516015!GO:0000059;protein import into nucleus, docking;0.000681135953516015!GO:0006352;transcription initiation;0.000711282063040468!GO:0016363;nuclear matrix;0.000740089280671983!GO:0046983;protein dimerization activity;0.000746621274040881!GO:0008186;RNA-dependent ATPase activity;0.000748011688279785!GO:0042440;pigment metabolic process;0.000820550154999077!GO:0003702;RNA polymerase II transcription factor activity;0.000828632626066826!GO:0033116;ER-Golgi intermediate compartment membrane;0.000829044075820976!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000846851980764188!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000846851980764188!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000846851980764188!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.000846851980764188!GO:0006302;double-strand break repair;0.00100635286647933!GO:0051287;NAD binding;0.00102460943844028!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00103093915434798!GO:0000786;nucleosome;0.00105178294247958!GO:0051052;regulation of DNA metabolic process;0.00109559098301652!GO:0030663;COPI coated vesicle membrane;0.00119852756013097!GO:0030126;COPI vesicle coat;0.00119852756013097!GO:0030384;phosphoinositide metabolic process;0.00123605277694666!GO:0007017;microtubule-based process;0.00123605277694666!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.00126743633498678!GO:0031970;organelle envelope lumen;0.00126743633498678!GO:0007050;cell cycle arrest;0.00127600650193379!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00128554315608222!GO:0048037;cofactor binding;0.00128987840641097!GO:0005791;rough endoplasmic reticulum;0.00139827965623628!GO:0007052;mitotic spindle organization and biogenesis;0.00143589771017457!GO:0006401;RNA catabolic process;0.00145962621499039!GO:0006643;membrane lipid metabolic process;0.00147102543256294!GO:0048487;beta-tubulin binding;0.00147677309956601!GO:0008094;DNA-dependent ATPase activity;0.00148085262911904!GO:0006497;protein amino acid lipidation;0.00151787197543968!GO:0007059;chromosome segregation;0.00159266517145161!GO:0008168;methyltransferase activity;0.00163777572401206!GO:0042158;lipoprotein biosynthetic process;0.00164483715694103!GO:0016741;transferase activity, transferring one-carbon groups;0.00166704361522813!GO:0000287;magnesium ion binding;0.00167472644757101!GO:0031902;late endosome membrane;0.0017006935211999!GO:0065009;regulation of a molecular function;0.0017275881381864!GO:0043284;biopolymer biosynthetic process;0.00175831730526804!GO:0051920;peroxiredoxin activity;0.00177403988572693!GO:0007041;lysosomal transport;0.00177832000701534!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00179233580443429!GO:0005684;U2-dependent spliceosome;0.00183002669031432!GO:0045941;positive regulation of transcription;0.00184389505580089!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0019167038641685!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0019167038641685!GO:0007040;lysosome organization and biogenesis;0.00192681216931314!GO:0005669;transcription factor TFIID complex;0.00197320427552181!GO:0005905;coated pit;0.00198363772195256!GO:0048500;signal recognition particle;0.0020487367566893!GO:0006405;RNA export from nucleus;0.00208125172666546!GO:0004004;ATP-dependent RNA helicase activity;0.00208236410282726!GO:0008022;protein C-terminus binding;0.00216398970191682!GO:0018196;peptidyl-asparagine modification;0.00225636447767446!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00225636447767446!GO:0006506;GPI anchor biosynthetic process;0.00248722130640875!GO:0006891;intra-Golgi vesicle-mediated transport;0.00249448232263985!GO:0045893;positive regulation of transcription, DNA-dependent;0.00251065025698643!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00251087990239587!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00251538807774901!GO:0030658;transport vesicle membrane;0.00255701486237278!GO:0000776;kinetochore;0.00264224927671665!GO:0016197;endosome transport;0.00264426550342404!GO:0003678;DNA helicase activity;0.00265543480073024!GO:0031072;heat shock protein binding;0.00268096311831416!GO:0006505;GPI anchor metabolic process;0.00268731478478564!GO:0030137;COPI-coated vesicle;0.00278193025530023!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00290812650350756!GO:0003746;translation elongation factor activity;0.00306997915952429!GO:0004167;dopachrome isomerase activity;0.00306997915952429!GO:0005657;replication fork;0.00308557085751901!GO:0051087;chaperone binding;0.00309588076296038!GO:0000096;sulfur amino acid metabolic process;0.00315775645695382!GO:0031323;regulation of cellular metabolic process;0.00330064342829304!GO:0030118;clathrin coat;0.00334487077606845!GO:0007033;vacuole organization and biogenesis;0.00345482679634974!GO:0006611;protein export from nucleus;0.00355124477359712!GO:0051252;regulation of RNA metabolic process;0.00357451689427763!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00375599519733824!GO:0005758;mitochondrial intermembrane space;0.00386843528567173!GO:0004674;protein serine/threonine kinase activity;0.00388715324715591!GO:0030521;androgen receptor signaling pathway;0.00388995155644191!GO:0030176;integral to endoplasmic reticulum membrane;0.00412404632417461!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00417845737725148!GO:0015002;heme-copper terminal oxidase activity;0.00417845737725148!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00417845737725148!GO:0004129;cytochrome-c oxidase activity;0.00417845737725148!GO:0008632;apoptotic program;0.00428126944548451!GO:0005876;spindle microtubule;0.00437504364487119!GO:0030133;transport vesicle;0.00455022925059145!GO:0006338;chromatin remodeling;0.00456113293841355!GO:0006509;membrane protein ectodomain proteolysis;0.00465612496376143!GO:0033619;membrane protein proteolysis;0.00465612496376143!GO:0051539;4 iron, 4 sulfur cluster binding;0.0046807214708574!GO:0016791;phosphoric monoester hydrolase activity;0.00490766054801298!GO:0006672;ceramide metabolic process;0.00518805898326821!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00520047960259972!GO:0045047;protein targeting to ER;0.00520047960259972!GO:0008092;cytoskeletal protein binding;0.00531176449160022!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0053648822191201!GO:0008047;enzyme activator activity;0.00547145384978737!GO:0006595;polyamine metabolic process;0.0055311595025984!GO:0030027;lamellipodium;0.00556370060574951!GO:0048522;positive regulation of cellular process;0.00557108526713804!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00560560659405812!GO:0030660;Golgi-associated vesicle membrane;0.00575490023079438!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.00604235104203128!GO:0048154;S100 beta binding;0.0061491154114486!GO:0007243;protein kinase cascade;0.00615643392923094!GO:0008610;lipid biosynthetic process;0.00645477909238733!GO:0006350;transcription;0.0065146338899464!GO:0008312;7S RNA binding;0.0065146338899464!GO:0006644;phospholipid metabolic process;0.00654227287916331!GO:0035258;steroid hormone receptor binding;0.00671561981704076!GO:0016272;prefoldin complex;0.00681931239562059!GO:0000086;G2/M transition of mitotic cell cycle;0.00686187475721752!GO:0006007;glucose catabolic process;0.00706798493600176!GO:0008234;cysteine-type peptidase activity;0.0071638048465852!GO:0008320;protein transmembrane transporter activity;0.00726936757209951!GO:0016584;nucleosome positioning;0.00748495212275208!GO:0008287;protein serine/threonine phosphatase complex;0.00760641782146523!GO:0006417;regulation of translation;0.00782515616215649!GO:0043488;regulation of mRNA stability;0.00787748644497979!GO:0043487;regulation of RNA stability;0.00787748644497979!GO:0030496;midbody;0.00865517682375341!GO:0003684;damaged DNA binding;0.0086793805264661!GO:0043022;ribosome binding;0.00869199556893827!GO:0003711;transcription elongation regulator activity;0.00870962329029859!GO:0032508;DNA duplex unwinding;0.00870962329029859!GO:0032392;DNA geometric change;0.00870962329029859!GO:0001726;ruffle;0.00871421243640767!GO:0045045;secretory pathway;0.0087952446476947!GO:0006519;amino acid and derivative metabolic process;0.00881454717149414!GO:0005774;vacuolar membrane;0.00895492398657096!GO:0000339;RNA cap binding;0.00903542715093747!GO:0031901;early endosome membrane;0.00904261508595241!GO:0046519;sphingoid metabolic process;0.00905059791062668!GO:0030036;actin cytoskeleton organization and biogenesis;0.00923654952209566!GO:0050811;GABA receptor binding;0.00960968478054394!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00965229045514506!GO:0042393;histone binding;0.00984967877736139!GO:0004527;exonuclease activity;0.00985032884204648!GO:0008180;signalosome;0.0101235119769764!GO:0046483;heterocycle metabolic process;0.0103033529338404!GO:0030503;regulation of cell redox homeostasis;0.0103782410347688!GO:0051540;metal cluster binding;0.0106929662181013!GO:0051536;iron-sulfur cluster binding;0.0106929662181013!GO:0004722;protein serine/threonine phosphatase activity;0.0108473697587021!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0112307187192379!GO:0005832;chaperonin-containing T-complex;0.0118867862655004!GO:0005637;nuclear inner membrane;0.0121361966114718!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.0122098350989926!GO:0016311;dephosphorylation;0.0128644683490287!GO:0050681;androgen receptor binding;0.0128788436892251!GO:0009451;RNA modification;0.0130785015761624!GO:0045892;negative regulation of transcription, DNA-dependent;0.0131443917669787!GO:0033673;negative regulation of kinase activity;0.0132676994585755!GO:0006469;negative regulation of protein kinase activity;0.0132676994585755!GO:0030518;steroid hormone receptor signaling pathway;0.0137056720125052!GO:0051348;negative regulation of transferase activity;0.0137333750045383!GO:0031647;regulation of protein stability;0.0139140039380698!GO:0004518;nuclease activity;0.0140492010751592!GO:0019843;rRNA binding;0.014058965807212!GO:0032200;telomere organization and biogenesis;0.014097947499436!GO:0000723;telomere maintenance;0.014097947499436!GO:0065007;biological regulation;0.0142529172692221!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0147407165187441!GO:0031326;regulation of cellular biosynthetic process;0.0151139272629722!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0152070228488543!GO:0008017;microtubule binding;0.015226896751406!GO:0033162;melanosome membrane;0.0155375430464579!GO:0045009;chitosome;0.0155375430464579!GO:0019748;secondary metabolic process;0.0155918562397793!GO:0016788;hydrolase activity, acting on ester bonds;0.0160160395743236!GO:0006582;melanin metabolic process;0.0161248058468179!GO:0006583;melanin biosynthetic process from tyrosine;0.0161248058468179!GO:0042438;melanin biosynthetic process;0.0161248058468179!GO:0006289;nucleotide-excision repair;0.0161248058468179!GO:0009003;signal peptidase activity;0.0166180339637848!GO:0006807;nitrogen compound metabolic process;0.0166497313543932!GO:0009308;amine metabolic process;0.0167881620793146!GO:0000209;protein polyubiquitination;0.0168081958539202!GO:0017166;vinculin binding;0.0169705276401395!GO:0005938;cell cortex;0.0169705276401395!GO:0048066;pigmentation during development;0.0169965953399236!GO:0010468;regulation of gene expression;0.017006080005738!GO:0016044;membrane organization and biogenesis;0.0173317360213595!GO:0022411;cellular component disassembly;0.0173666792132159!GO:0009116;nucleoside metabolic process;0.0176730297053957!GO:0030119;AP-type membrane coat adaptor complex;0.0176730297053957!GO:0000097;sulfur amino acid biosynthetic process;0.0176966051667366!GO:0031124;mRNA 3'-end processing;0.0179335167640317!GO:0051128;regulation of cellular component organization and biogenesis;0.017991310004376!GO:0000922;spindle pole;0.0180753566771945!GO:0006661;phosphatidylinositol biosynthetic process;0.0182696625212924!GO:0019887;protein kinase regulator activity;0.0182696625212924!GO:0008361;regulation of cell size;0.0184670780535271!GO:0030508;thiol-disulfide exchange intermediate activity;0.0189647405963621!GO:0009066;aspartate family amino acid metabolic process;0.019570561987909!GO:0006144;purine base metabolic process;0.0197751847051542!GO:0043407;negative regulation of MAP kinase activity;0.0199809903761239!GO:0008139;nuclear localization sequence binding;0.0199809903761239!GO:0004721;phosphoprotein phosphatase activity;0.02026436653336!GO:0044437;vacuolar part;0.020344635153058!GO:0047485;protein N-terminus binding;0.020450475556625!GO:0030131;clathrin adaptor complex;0.020450475556625!GO:0006268;DNA unwinding during replication;0.0212374977183556!GO:0019783;small conjugating protein-specific protease activity;0.0216901323470211!GO:0042026;protein refolding;0.0216901323470211!GO:0022406;membrane docking;0.0217511672800507!GO:0048278;vesicle docking;0.0217511672800507!GO:0050790;regulation of catalytic activity;0.0217996456861455!GO:0019318;hexose metabolic process;0.0220790825323915!GO:0019207;kinase regulator activity;0.0221831067745206!GO:0006275;regulation of DNA replication;0.0226189867182978!GO:0006310;DNA recombination;0.022663122158926!GO:0004448;isocitrate dehydrogenase activity;0.0231330042598542!GO:0000910;cytokinesis;0.0231356892629561!GO:0016790;thiolester hydrolase activity;0.0236899846399979!GO:0006767;water-soluble vitamin metabolic process;0.0236956865571024!GO:0032981;mitochondrial respiratory chain complex I assembly;0.023695845326663!GO:0010257;NADH dehydrogenase complex assembly;0.023695845326663!GO:0033108;mitochondrial respiratory chain complex assembly;0.023695845326663!GO:0005869;dynactin complex;0.0239413854861184!GO:0009070;serine family amino acid biosynthetic process;0.0245104137086667!GO:0007030;Golgi organization and biogenesis;0.0245832465688388!GO:0016408;C-acyltransferase activity;0.0245832465688388!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0247661974971139!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0247661974971139!GO:0000118;histone deacetylase complex;0.0250325535861565!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0256136179183523!GO:0045039;protein import into mitochondrial inner membrane;0.0256136179183523!GO:0006607;NLS-bearing substrate import into nucleus;0.0256136179183523!GO:0004563;beta-N-acetylhexosaminidase activity;0.0256136179183523!GO:0016407;acetyltransferase activity;0.0257546943983462!GO:0004843;ubiquitin-specific protease activity;0.0257850326707007!GO:0003857;3-hydroxyacyl-CoA dehydrogenase activity;0.0263458671558243!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0263823489423652!GO:0005996;monosaccharide metabolic process;0.0265121458911977!GO:0005744;mitochondrial inner membrane presequence translocase complex;0.0268138034582136!GO:0030140;trans-Golgi network transport vesicle;0.0273657486728603!GO:0007021;tubulin folding;0.0274213663654347!GO:0006400;tRNA modification;0.027593400333987!GO:0008652;amino acid biosynthetic process;0.0281986680060205!GO:0007264;small GTPase mediated signal transduction;0.0281986680060205!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0281986680060205!GO:0006376;mRNA splice site selection;0.0284576897021164!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0284576897021164!GO:0006733;oxidoreduction coenzyme metabolic process;0.0285570730603016!GO:0004300;enoyl-CoA hydratase activity;0.0287796192402112!GO:0046488;phosphatidylinositol metabolic process;0.0290371327099667!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0292061586478438!GO:0006984;ER-nuclear signaling pathway;0.0295582807312731!GO:0006904;vesicle docking during exocytosis;0.0298262279619847!GO:0006100;tricarboxylic acid cycle intermediate metabolic process;0.0300254146790145!GO:0006541;glutamine metabolic process;0.0305092743903879!GO:0043624;cellular protein complex disassembly;0.0308135605825047!GO:0030134;ER to Golgi transport vesicle;0.0311085654083383!GO:0008637;apoptotic mitochondrial changes;0.0311517426961692!GO:0009112;nucleobase metabolic process;0.0318334370564636!GO:0000781;chromosome, telomeric region;0.0318933693809345!GO:0004659;prenyltransferase activity;0.0322492453372268!GO:0030125;clathrin vesicle coat;0.0325749066212077!GO:0030665;clathrin coated vesicle membrane;0.0325749066212077!GO:0031577;spindle checkpoint;0.0327001962869255!GO:0007004;telomere maintenance via telomerase;0.0328496633451572!GO:0006564;L-serine biosynthetic process;0.0334644236356323!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0339356461992787!GO:0016049;cell growth;0.0341701396393845!GO:0030127;COPII vesicle coat;0.0343676464972657!GO:0012507;ER to Golgi transport vesicle membrane;0.0343676464972657!GO:0006740;NADPH regeneration;0.0344246886486962!GO:0006098;pentose-phosphate shunt;0.0344246886486962!GO:0006378;mRNA polyadenylation;0.0345371332898029!GO:0015036;disulfide oxidoreductase activity;0.0347137405231505!GO:0004003;ATP-dependent DNA helicase activity;0.0354111027882362!GO:0005784;translocon complex;0.0356266422218402!GO:0005765;lysosomal membrane;0.0362503756542696!GO:0001558;regulation of cell growth;0.0369927405265362!GO:0030132;clathrin coat of coated pit;0.0377787321764812!GO:0006779;porphyrin biosynthetic process;0.0380641193409033!GO:0033014;tetrapyrrole biosynthetic process;0.0380641193409033!GO:0031123;RNA 3'-end processing;0.038724608675998!GO:0048146;positive regulation of fibroblast proliferation;0.039183252455391!GO:0030262;apoptotic nuclear changes;0.0395242283176782!GO:0030145;manganese ion binding;0.0395242283176782!GO:0004221;ubiquitin thiolesterase activity;0.0396380261003773!GO:0005754;mitochondrial proton-transporting ATP synthase, catalytic core;0.0403454488882678!GO:0000275;mitochondrial proton-transporting ATP synthase complex, catalytic core F(1);0.0403454488882678!GO:0045267;proton-transporting ATP synthase, catalytic core;0.0403454488882678!GO:0032774;RNA biosynthetic process;0.040925389872836!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0420577512092881!GO:0006470;protein amino acid dephosphorylation;0.0421563415562174!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0422979048149527!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0424052935816259!GO:0008538;proteasome activator activity;0.0424182862217165!GO:0032984;macromolecular complex disassembly;0.0429244444954147!GO:0048144;fibroblast proliferation;0.042956069865741!GO:0048145;regulation of fibroblast proliferation;0.042956069865741!GO:0030029;actin filament-based process;0.0432285627549354!GO:0006351;transcription, DNA-dependent;0.0436784154139588!GO:0009303;rRNA transcription;0.0442125615118839!GO:0007569;cell aging;0.044241570290753!GO:0030433;ER-associated protein catabolic process;0.0442945582458765!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0442945582458765!GO:0045792;negative regulation of cell size;0.0445496105125445!GO:0008333;endosome to lysosome transport;0.0449945161636929!GO:0005096;GTPase activator activity;0.0451990154316984!GO:0003677;DNA binding;0.0452454548851489!GO:0030522;intracellular receptor-mediated signaling pathway;0.0454307372755699!GO:0003923;GPI-anchor transamidase activity;0.0454307372755699!GO:0016255;attachment of GPI anchor to protein;0.0454307372755699!GO:0042765;GPI-anchor transamidase complex;0.0454307372755699!GO:0006730;one-carbon compound metabolic process;0.0455650088000862!GO:0048468;cell development;0.0457232405968053!GO:0046982;protein heterodimerization activity;0.0459305861099328!GO:0008536;Ran GTPase binding;0.0460466690426243!GO:0006467;protein thiol-disulfide exchange;0.0461646880235121!GO:0000726;non-recombinational repair;0.0463831988551795!GO:0009067;aspartate family amino acid biosynthetic process;0.047124698105351!GO:0001725;stress fiber;0.0474628847842053!GO:0032432;actin filament bundle;0.0474628847842053!GO:0000082;G1/S transition of mitotic cell cycle;0.0484405929955854!GO:0008097;5S rRNA binding;0.0499391148357386 | |||
|sample_id=10514 | |sample_id=10514 | ||
|sample_note= | |sample_note= | ||
| Line 76: | Line 99: | ||
|sample_tissue=skin | |sample_tissue=skin | ||
|top_motifs=ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:3.13666928814;bHLH_family:2.89801511419;ESRRA:1.68976229363;SREBF1,2:1.66677089602;CDC5L:1.58470903737;ELK1,4_GABP{A,B1}:1.56986205672;PRRX1,2:1.56425275168;PAX4:1.55910456632;EN1,2:1.52877130503;HOX{A6,A7,B6,B7}:1.52745885692;POU6F1:1.49518598598;NR5A1,2:1.46151894488;HOX{A4,D4}:1.41800464703;PAX8:1.38706220849;CRX:1.30150020294;HES1:1.21623101418;NR3C1:1.08529267703;PAX1,9:1.01138961129;NFIX:1.00877460393;NKX2-1,4:0.976383856842;RXR{A,B,G}:0.949451872959;SOX{8,9,10}:0.934585710046;FOX{F1,F2,J1}:0.886151430816;PAX6:0.790782742127;NRF1:0.751524577537;ZBTB16:0.741272848912;POU2F1..3:0.738722061906;FOXA2:0.722622915032;PBX1:0.710242029281;PAX2:0.704189224331;TOPORS:0.688550287889;OCT4_SOX2{dimer}:0.679885192186;ZNF143:0.655114149007;ARID5B:0.618142601406;TEF:0.615795976988;NANOG:0.611721020111;NFY{A,B,C}:0.580717394525;NFE2L1:0.573878114521;ELF1,2,4:0.573327440031;GFI1:0.556954347827;RORA:0.536454890042;YY1:0.525430687818;AHR_ARNT_ARNT2:0.50332153348;VSX1,2:0.452744519494;LHX3,4:0.443271054794;MYB:0.433966596487;STAT5{A,B}:0.433314173929;AIRE:0.428225652874;NFIL3:0.427443659249;SOX17:0.399524309441;CREB1:0.381568920594;E2F1..5:0.376289832545;TFDP1:0.34420309935;ATF4:0.312131107556;FOXQ1:0.309218815741;ATF5_CREB3:0.303429271041;PPARG:0.298456883162;ZNF423:0.298131540389;POU1F1:0.29528751736;GZF1:0.293446543859;CEBPA,B_DDIT3:0.287076943249;JUN:0.278173658757;TLX2:0.269079562198;SOX5:0.210273675658;RBPJ:0.209602057266;FOXP1:0.198071469236;SOX2:0.188468025794;REST:0.184542824295;MEF2{A,B,C,D}:0.175722138697;NKX2-3_NKX2-5:0.172068626;HOX{A5,B5}:0.170954837075;EVI1:0.159823505245;EGR1..3:0.146841892671;TLX1..3_NFIC{dimer}:0.140649558786;HNF4A_NR2F1,2:0.129267415416;FOXM1:0.11777769857;XBP1:0.108618417595;HIC1:0.0973258292768;NKX3-2:0.0869456841115;FOXD3:0.081570090622;TBX4,5:0.0396893963267;NKX2-2,8:0.0323457741179;ZNF384:0.012125794145;BREu{core}:0.0110507918269;MAFB:0.00681292152005;POU3F1..4:-0.00637774734138;GATA6:-0.0152390644996;NR1H4:-0.0162871024058;LEF1_TCF7_TCF7L1,2:-0.0362043779946;HLF:-0.0372303296626;MYFfamily:-0.0400951500198;IKZF2:-0.0510210704655;STAT1,3:-0.0546328493755;GATA4:-0.0602247224917;FOSL2:-0.0633648631657;IKZF1:-0.071817785433;XCPE1{core}:-0.0755919115041;CUX2:-0.0777701905671;TFAP2{A,C}:-0.0815669867938;TGIF1:-0.0863819900476;RFX2..5_RFXANK_RFXAP:-0.0902431360845;HIF1A:-0.0913133021794;SP1:-0.104611762599;RUNX1..3:-0.111955517831;UFEwm:-0.114873336558;NFE2:-0.122922256438;FOX{D1,D2}:-0.12624534991;DMAP1_NCOR{1,2}_SMARC:-0.129312385705;PRDM1:-0.134643313643;ALX4:-0.136501970909;NKX6-1,2:-0.162121100149;RFX1:-0.181509919077;TFAP2B:-0.190722413938;SPI1:-0.204473130483;PDX1:-0.212574670678;BACH2:-0.220467656494;T:-0.221932857612;ZIC1..3:-0.229318868231;FOXP3:-0.229955361901;NHLH1,2:-0.230401078758;ESR1:-0.232849189206;TEAD1:-0.262908803963;SPIB:-0.271912573657;ZFP161:-0.275247170302;FOS_FOS{B,L1}_JUN{B,D}:-0.278579156626;ZBTB6:-0.279961874359;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.281866185739;GTF2I:-0.287120958528;PAX3,7:-0.295523209524;ADNP_IRX_SIX_ZHX:-0.301933621592;HNF1A:-0.311719758374;DBP:-0.311838539781;MED-1{core}:-0.317161819506;AR:-0.321010884587;TP53:-0.325728538151;STAT2,4,6:-0.327886724129;FOX{I1,J2}:-0.331969306547;IRF1,2:-0.352036365193;MAZ:-0.353055692234;ONECUT1,2:-0.376447421464;GFI1B:-0.381915173159;ETS1,2:-0.382525910391;FOXL1:-0.38368763435;NFKB1_REL_RELA:-0.386990618168;MZF1:-0.396349727082;MYBL2:-0.398037654671;IRF7:-0.405526804385;FOXN1:-0.418344728746;NANOG{mouse}:-0.428445089638;PAX5:-0.446545700118;ATF2:-0.448470217325;SMAD1..7,9:-0.45345455308;BPTF:-0.462742763322;EBF1:-0.474768846219;GCM1,2:-0.478719461729;MTE{core}:-0.479565861904;TBP:-0.495296417985;SNAI1..3:-0.495477458687;POU5F1:-0.527937662661;SPZ1:-0.554487501872;PATZ1:-0.554661732926;ZEB1:-0.561571974236;NFATC1..3:-0.567931476729;KLF4:-0.570989050569;RREB1:-0.613529435097;GTF2A1,2:-0.621694737127;PITX1..3:-0.655955353675;ZNF148:-0.663247734936;TFCP2:-0.679075716384;GLI1..3:-0.704086789925;MYOD1:-0.710443625173;NFE2L2:-0.745248219404;HBP1_HMGB_SSRP1_UBTF:-0.749882213924;FOXO1,3,4:-0.770904257065;HSF1,2:-0.775285988346;HOXA9_MEIS1:-0.782631479076;CDX1,2,4:-0.799149086223;LMO2:-0.809535030938;SRF:-0.810233357519;HMGA1,2:-0.917799999498;ZNF238:-0.934825760402;TAL1_TCF{3,4,12}:-0.95231638609;MTF1:-0.966629352667;NKX3-1:-1.08141359011;ATF6:-1.11531480572;EP300:-1.14428365047;ALX1:-1.17595518614;HAND1,2:-1.33857840491;NR6A1:-1.34317387831;TFAP4:-1.35270443458;HMX1:-1.62752475776;RXRA_VDR{dimer}:-2.14932336603 | |top_motifs=ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:3.13666928814;bHLH_family:2.89801511419;ESRRA:1.68976229363;SREBF1,2:1.66677089602;CDC5L:1.58470903737;ELK1,4_GABP{A,B1}:1.56986205672;PRRX1,2:1.56425275168;PAX4:1.55910456632;EN1,2:1.52877130503;HOX{A6,A7,B6,B7}:1.52745885692;POU6F1:1.49518598598;NR5A1,2:1.46151894488;HOX{A4,D4}:1.41800464703;PAX8:1.38706220849;CRX:1.30150020294;HES1:1.21623101418;NR3C1:1.08529267703;PAX1,9:1.01138961129;NFIX:1.00877460393;NKX2-1,4:0.976383856842;RXR{A,B,G}:0.949451872959;SOX{8,9,10}:0.934585710046;FOX{F1,F2,J1}:0.886151430816;PAX6:0.790782742127;NRF1:0.751524577537;ZBTB16:0.741272848912;POU2F1..3:0.738722061906;FOXA2:0.722622915032;PBX1:0.710242029281;PAX2:0.704189224331;TOPORS:0.688550287889;OCT4_SOX2{dimer}:0.679885192186;ZNF143:0.655114149007;ARID5B:0.618142601406;TEF:0.615795976988;NANOG:0.611721020111;NFY{A,B,C}:0.580717394525;NFE2L1:0.573878114521;ELF1,2,4:0.573327440031;GFI1:0.556954347827;RORA:0.536454890042;YY1:0.525430687818;AHR_ARNT_ARNT2:0.50332153348;VSX1,2:0.452744519494;LHX3,4:0.443271054794;MYB:0.433966596487;STAT5{A,B}:0.433314173929;AIRE:0.428225652874;NFIL3:0.427443659249;SOX17:0.399524309441;CREB1:0.381568920594;E2F1..5:0.376289832545;TFDP1:0.34420309935;ATF4:0.312131107556;FOXQ1:0.309218815741;ATF5_CREB3:0.303429271041;PPARG:0.298456883162;ZNF423:0.298131540389;POU1F1:0.29528751736;GZF1:0.293446543859;CEBPA,B_DDIT3:0.287076943249;JUN:0.278173658757;TLX2:0.269079562198;SOX5:0.210273675658;RBPJ:0.209602057266;FOXP1:0.198071469236;SOX2:0.188468025794;REST:0.184542824295;MEF2{A,B,C,D}:0.175722138697;NKX2-3_NKX2-5:0.172068626;HOX{A5,B5}:0.170954837075;EVI1:0.159823505245;EGR1..3:0.146841892671;TLX1..3_NFIC{dimer}:0.140649558786;HNF4A_NR2F1,2:0.129267415416;FOXM1:0.11777769857;XBP1:0.108618417595;HIC1:0.0973258292768;NKX3-2:0.0869456841115;FOXD3:0.081570090622;TBX4,5:0.0396893963267;NKX2-2,8:0.0323457741179;ZNF384:0.012125794145;BREu{core}:0.0110507918269;MAFB:0.00681292152005;POU3F1..4:-0.00637774734138;GATA6:-0.0152390644996;NR1H4:-0.0162871024058;LEF1_TCF7_TCF7L1,2:-0.0362043779946;HLF:-0.0372303296626;MYFfamily:-0.0400951500198;IKZF2:-0.0510210704655;STAT1,3:-0.0546328493755;GATA4:-0.0602247224917;FOSL2:-0.0633648631657;IKZF1:-0.071817785433;XCPE1{core}:-0.0755919115041;CUX2:-0.0777701905671;TFAP2{A,C}:-0.0815669867938;TGIF1:-0.0863819900476;RFX2..5_RFXANK_RFXAP:-0.0902431360845;HIF1A:-0.0913133021794;SP1:-0.104611762599;RUNX1..3:-0.111955517831;UFEwm:-0.114873336558;NFE2:-0.122922256438;FOX{D1,D2}:-0.12624534991;DMAP1_NCOR{1,2}_SMARC:-0.129312385705;PRDM1:-0.134643313643;ALX4:-0.136501970909;NKX6-1,2:-0.162121100149;RFX1:-0.181509919077;TFAP2B:-0.190722413938;SPI1:-0.204473130483;PDX1:-0.212574670678;BACH2:-0.220467656494;T:-0.221932857612;ZIC1..3:-0.229318868231;FOXP3:-0.229955361901;NHLH1,2:-0.230401078758;ESR1:-0.232849189206;TEAD1:-0.262908803963;SPIB:-0.271912573657;ZFP161:-0.275247170302;FOS_FOS{B,L1}_JUN{B,D}:-0.278579156626;ZBTB6:-0.279961874359;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.281866185739;GTF2I:-0.287120958528;PAX3,7:-0.295523209524;ADNP_IRX_SIX_ZHX:-0.301933621592;HNF1A:-0.311719758374;DBP:-0.311838539781;MED-1{core}:-0.317161819506;AR:-0.321010884587;TP53:-0.325728538151;STAT2,4,6:-0.327886724129;FOX{I1,J2}:-0.331969306547;IRF1,2:-0.352036365193;MAZ:-0.353055692234;ONECUT1,2:-0.376447421464;GFI1B:-0.381915173159;ETS1,2:-0.382525910391;FOXL1:-0.38368763435;NFKB1_REL_RELA:-0.386990618168;MZF1:-0.396349727082;MYBL2:-0.398037654671;IRF7:-0.405526804385;FOXN1:-0.418344728746;NANOG{mouse}:-0.428445089638;PAX5:-0.446545700118;ATF2:-0.448470217325;SMAD1..7,9:-0.45345455308;BPTF:-0.462742763322;EBF1:-0.474768846219;GCM1,2:-0.478719461729;MTE{core}:-0.479565861904;TBP:-0.495296417985;SNAI1..3:-0.495477458687;POU5F1:-0.527937662661;SPZ1:-0.554487501872;PATZ1:-0.554661732926;ZEB1:-0.561571974236;NFATC1..3:-0.567931476729;KLF4:-0.570989050569;RREB1:-0.613529435097;GTF2A1,2:-0.621694737127;PITX1..3:-0.655955353675;ZNF148:-0.663247734936;TFCP2:-0.679075716384;GLI1..3:-0.704086789925;MYOD1:-0.710443625173;NFE2L2:-0.745248219404;HBP1_HMGB_SSRP1_UBTF:-0.749882213924;FOXO1,3,4:-0.770904257065;HSF1,2:-0.775285988346;HOXA9_MEIS1:-0.782631479076;CDX1,2,4:-0.799149086223;LMO2:-0.809535030938;SRF:-0.810233357519;HMGA1,2:-0.917799999498;ZNF238:-0.934825760402;TAL1_TCF{3,4,12}:-0.95231638609;MTF1:-0.966629352667;NKX3-1:-1.08141359011;ATF6:-1.11531480572;EP300:-1.14428365047;ALX1:-1.17595518614;HAND1,2:-1.33857840491;NR6A1:-1.34317387831;TFAP4:-1.35270443458;HMX1:-1.62752475776;RXRA_VDR{dimer}:-2.14932336603 | ||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10514-107E1;search_select_hide=table117:FF:10514-107E1 | |||
}} | }} | ||
Latest revision as of 14:28, 3 June 2020
| Name: | melanoma cell line:COLO 679 |
|---|---|
| Species: | Human (Homo sapiens) |
| Library ID: | CNhs11281 |
| Sample type: | cell lines |
| Genomic View: | UCSC |
| RefEX: | Specific genes |
| CAGEd-oPOSSUM: | link |
| ZENBU report : | link |
| Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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| CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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| Download raw sequence, BAM & CTSS | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11281
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11281
| Novel motif | Logo | P-value |
|---|---|---|
| 1 | 1 | 0.973 |
| 10 | 10 | 0.818 |
| 100 | 100 | 0.679 |
| 101 | 101 | 0.821 |
| 102 | 102 | 0.136 |
| 103 | 103 | 0.731 |
| 104 | 104 | 0.981 |
| 105 | 105 | 0.0717 |
| 106 | 106 | 0.0213 |
| 107 | 107 | 0.0921 |
| 108 | 108 | 0.669 |
| 109 | 109 | 0.93 |
| 11 | 11 | 0.39 |
| 110 | 110 | 0.741 |
| 111 | 111 | 0.0425 |
| 112 | 112 | 0.58 |
| 113 | 113 | 0.058 |
| 114 | 114 | 0.0225 |
| 115 | 115 | 0.573 |
| 116 | 116 | 0.218 |
| 117 | 117 | 0.289 |
| 118 | 118 | 0.636 |
| 119 | 119 | 0.075 |
| 12 | 12 | 0.149 |
| 120 | 120 | 0.196 |
| 121 | 121 | 0.62 |
| 122 | 122 | 0.323 |
| 123 | 123 | 0.231 |
| 124 | 124 | 0.571 |
| 125 | 125 | 0.259 |
| 126 | 126 | 0.442 |
| 127 | 127 | 0.224 |
| 128 | 128 | 0.0199 |
| 129 | 129 | 0.539 |
| 13 | 13 | 0.639 |
| 130 | 130 | 0.591 |
| 131 | 131 | 0.142 |
| 132 | 132 | 0.412 |
| 133 | 133 | 0.123 |
| 134 | 134 | 0.763 |
| 135 | 135 | 0.533 |
| 136 | 136 | 0.0127 |
| 137 | 137 | 0.325 |
| 138 | 138 | 0.43 |
| 139 | 139 | 0.0223 |
| 14 | 14 | 0.515 |
| 140 | 140 | 0.0912 |
| 141 | 141 | 0.854 |
| 142 | 142 | 0.653 |
| 143 | 143 | 0.0614 |
| 144 | 144 | 0.614 |
| 145 | 145 | 0.655 |
| 146 | 146 | 0.5 |
| 147 | 147 | 0.821 |
| 148 | 148 | 0.879 |
| 149 | 149 | 0.453 |
| 15 | 15 | 0.239 |
| 150 | 150 | 0.311 |
| 151 | 151 | 0.39 |
| 152 | 152 | 0.611 |
| 153 | 153 | 0.592 |
| 154 | 154 | 0.596 |
| 155 | 155 | 0.349 |
| 156 | 156 | 0.524 |
| 157 | 157 | 0.777 |
| 158 | 158 | 0.704 |
| 159 | 159 | 0.0896 |
| 16 | 16 | 0.94 |
| 160 | 160 | 0.0458 |
| 161 | 161 | 0.0378 |
| 162 | 162 | 0.648 |
| 163 | 163 | 0.661 |
| 164 | 164 | 0.728 |
| 165 | 165 | 0.25 |
| 166 | 166 | 0.0613 |
| 167 | 167 | 0.912 |
| 168 | 168 | 0.445 |
| 169 | 169 | 0.206 |
| 17 | 17 | 0.136 |
| 18 | 18 | 0.57 |
| 19 | 19 | 0.0843 |
| 2 | 2 | 0.155 |
| 20 | 20 | 0.112 |
| 21 | 21 | 0.297 |
| 22 | 22 | 0.519 |
| 23 | 23 | 0.0721 |
| 24 | 24 | 0.545 |
| 25 | 25 | 0.764 |
| 26 | 26 | 0.936 |
| 27 | 27 | 0.193 |
| 28 | 28 | 0.649 |
| 29 | 29 | 0.683 |
| 3 | 3 | 0.478 |
| 30 | 30 | 0.21 |
| 31 | 31 | 0.51 |
| 32 | 32 | 1.38527e-4 |
| 33 | 33 | 0.976 |
| 34 | 34 | 0.219 |
| 35 | 35 | 0.957 |
| 36 | 36 | 0.558 |
| 37 | 37 | 0.939 |
| 38 | 38 | 0.569 |
| 39 | 39 | 0.38 |
| 4 | 4 | 0.688 |
| 40 | 40 | 0.0664 |
| 41 | 41 | 0.926 |
| 42 | 42 | 0.537 |
| 43 | 43 | 0.127 |
| 44 | 44 | 0.305 |
| 45 | 45 | 0.219 |
| 46 | 46 | 0.297 |
| 47 | 47 | 0.738 |
| 48 | 48 | 0.604 |
| 49 | 49 | 0.256 |
| 5 | 5 | 0.824 |
| 50 | 50 | 0.714 |
| 51 | 51 | 0.125 |
| 52 | 52 | 0.116 |
| 53 | 53 | 0.369 |
| 54 | 54 | 0.38 |
| 55 | 55 | 0.719 |
| 56 | 56 | 0.701 |
| 57 | 57 | 0.932 |
| 58 | 58 | 0.226 |
| 59 | 59 | 0.279 |
| 6 | 6 | 0.0487 |
| 60 | 60 | 0.167 |
| 61 | 61 | 0.709 |
| 62 | 62 | 0.0972 |
| 63 | 63 | 0.152 |
| 64 | 64 | 0.531 |
| 65 | 65 | 0.213 |
| 66 | 66 | 0.0641 |
| 67 | 67 | 0.576 |
| 68 | 68 | 0.00331 |
| 69 | 69 | 0.329 |
| 7 | 7 | 0.668 |
| 70 | 70 | 0.438 |
| 71 | 71 | 0.524 |
| 72 | 72 | 0.32 |
| 73 | 73 | 0.784 |
| 74 | 74 | 0.446 |
| 75 | 75 | 0.25 |
| 76 | 76 | 0.499 |
| 77 | 77 | 0.0293 |
| 78 | 78 | 0.246 |
| 79 | 79 | 0.0436 |
| 8 | 8 | 0.234 |
| 80 | 80 | 0.689 |
| 81 | 81 | 0.163 |
| 82 | 82 | 0.0256 |
| 83 | 83 | 0.0679 |
| 84 | 84 | 0.776 |
| 85 | 85 | 0.508 |
| 86 | 86 | 0.513 |
| 87 | 87 | 0.0756 |
| 88 | 88 | 0.408 |
| 89 | 89 | 0.122 |
| 9 | 9 | 0.281 |
| 90 | 90 | 0.806 |
| 91 | 91 | 0.0452 |
| 92 | 92 | 0.108 |
| 93 | 93 | 0.745 |
| 94 | 94 | 0.066 |
| 95 | 95 | 0.295 |
| 96 | 96 | 0.263 |
| 97 | 97 | 0.743 |
| 98 | 98 | 0.221 |
| 99 | 99 | 0.581 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11281
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0100849 melanoma cell line sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
DOID: Disease
4 (disease)
162 (cancer)
14566 (disease of cellular proliferation)
0050687 (cell type cancer)
1909 (melanoma)
UBERON: Anatomy
0000468 (multi-cellular organism)
0001003 (skin epidermis)
0002097 (skin of body)
0002199 (integument)
0000483 (epithelium)
0000479 (tissue)
0004121 (ectoderm-derived structure)
0000062 (organ)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0000119 (cell layer)
0003102 (surface structure)
0007376 (outer epithelium)
0010371 (ecto-epithelium)
0010317 (germ layer / neural crest derived structure)
0002416 (integumental system)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100849 (melanoma cell line sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
UBERON:0002532 (epiblast (generic))
UBERON:0006601 (presumptive ectoderm)
UBERON:0010316 (germ layer / neural crest)
