MCL coexpression mm9:248: Difference between revisions
From FANTOM5_SSTAR
No edit summary |
No edit summary |
||
Line 3: | Line 3: | ||
|coexpression_dpi_cluster_scores_median=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.996460114045282,0.0719044921483595,0.216639122756379,0.482059931916555,0.92676880362927,0.820727869040081,0.779465372800613,0.589886961321286,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0134759471663239,0.0121269368029194,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0 | |coexpression_dpi_cluster_scores_median=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.996460114045282,0.0719044921483595,0.216639122756379,0.482059931916555,0.92676880362927,0.820727869040081,0.779465372800613,0.589886961321286,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0134759471663239,0.0121269368029194,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0 | ||
|gostat_on_MCL_coexpression=GO:0050794;regulation of cellular process;0.00590710375771117;83993,245684,16871,211468,18736,380714,14683,20476,21834!GO:0050789;regulation of biological process;0.00590710375771117;83993,245684,16871,211468,18736,380714,14683,20476,21834!GO:0021983;pituitary gland development;0.00590710375771117;83993,18736!GO:0021536;diencephalon development;0.00590710375771117;83993,18736!GO:0065007;biological regulation;0.00590710375771117;83993,245684,16871,211468,18736,380714,14683,20476,21834!GO:0003700;transcription factor activity;0.00590710375771117;83993,18736,20476,21834,16871!GO:0043565;sequence-specific DNA binding;0.00642647008083665;18736,20476,21834,16871!GO:0045944;positive regulation of transcription from RNA polymerase II promoter;0.0112185472859472;83993,18736,21834!GO:0007417;central nervous system development;0.0112364024618341;83993,18736,16871!GO:0045893;positive regulation of transcription, DNA-dependent;0.0112364024618341;83993,18736,21834!GO:0035270;endocrine system development;0.0112364024618341;83993,18736!GO:0006355;regulation of transcription, DNA-dependent;0.0112364024618341;83993,18736,20476,21834,16871,211468!GO:0006351;transcription, DNA-dependent;0.0112364024618341;83993,18736,20476,21834,16871,211468!GO:0032774;RNA biosynthetic process;0.0112364024618341;83993,18736,20476,21834,16871,211468!GO:0045449;regulation of transcription;0.0112364024618341;83993,18736,20476,21834,16871,211468!GO:0032962;positive regulation of inositol trisphosphate biosynthetic process;0.0112364024618341;18736!GO:0040032;post-embryonic body morphogenesis;0.0112364024618341;14683!GO:0032958;inositol phosphate biosynthetic process;0.0112364024618341;18736!GO:0032960;regulation of inositol trisphosphate biosynthetic process;0.0112364024618341;18736!GO:0032959;inositol trisphosphate biosynthetic process;0.0112364024618341;18736!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0112364024618341;83993,18736,20476,21834,16871,211468!GO:0045941;positive regulation of transcription;0.0112364024618341;83993,18736,21834!GO:0006350;transcription;0.0112364024618341;83993,18736,20476,21834,16871,211468!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0112364024618341;83993,18736,21834!GO:0010468;regulation of gene expression;0.0124911522910315;83993,18736,20476,21834,16871,211468!GO:0048522;positive regulation of cellular process;0.0124911522910315;83993,18736,14683,21834!GO:0048732;gland development;0.0128309556366026;83993,18736!GO:0031323;regulation of cellular metabolic process;0.0128309556366026;83993,18736,20476,21834,16871,211468!GO:0009966;regulation of signal transduction;0.0128309556366026;380714,18736,245684!GO:0007275;multicellular organismal development;0.0128309556366026;83993,18736,14683,20476,21834,16871!GO:0021526;medial motor column neuron differentiation;0.0128309556366026;16871!GO:0006021;inositol biosynthetic process;0.0128309556366026;18736!GO:0043647;inositol phosphate metabolic process;0.0128309556366026;18736!GO:0032957;inositol trisphosphate metabolic process;0.0128309556366026;18736!GO:0060133;somatotropin secreting cell development;0.0128309556366026;18736!GO:0019222;regulation of metabolic process;0.0128309556366026;83993,18736,20476,21834,16871,211468!GO:0031325;positive regulation of cellular metabolic process;0.0128309556366026;83993,18736,21834!GO:0016070;RNA metabolic process;0.0138703516458522;83993,18736,20476,21834,16871,211468!GO:0009893;positive regulation of metabolic process;0.0138703516458522;83993,18736,21834!GO:0048518;positive regulation of biological process;0.0138703516458522;83993,18736,14683,21834!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.0147857581625108;83993,18736,21834!GO:0030900;forebrain development;0.0148460829282235;83993,18736!GO:0045165;cell fate commitment;0.0148460829282235;83993,18736!GO:0060126;somatotropin secreting cell differentiation;0.0148460829282235;18736!GO:0021523;somatic motor neuron differentiation;0.0148460829282235;16871!GO:0004887;thyroid hormone receptor activity;0.0148460829282235;21834!GO:0043567;regulation of insulin-like growth factor receptor signaling pathway;0.0148460829282235;18736!GO:0005667;transcription factor complex;0.0164725702998602;18736,20476,16871!GO:0006366;transcription from RNA polymerase II promoter;0.0165816177594602;83993,18736,21834!GO:0017158;regulation of calcium ion-dependent exocytosis;0.0172982678649299;380714!GO:0045913;positive regulation of carbohydrate metabolic process;0.0172982678649299;18736!GO:0045672;positive regulation of osteoclast differentiation;0.0172982678649299;14683!GO:0043255;regulation of carbohydrate biosynthetic process;0.0172982678649299;18736!GO:0048731;system development;0.0172982678649299;83993,18736,14683,21834,16871!GO:0002521;leukocyte differentiation;0.0194933648973085;18736,14683!GO:0000155;two-component sensor activity;0.0202358494253453;211468!GO:0010171;body morphogenesis;0.0202358494253453;14683!GO:0019899;enzyme binding;0.0202358494253453;380714,245684!GO:0005515;protein binding;0.0211253157868178;22094,83993,380714,18736,70615,20476,245684,21834!GO:0010467;gene expression;0.0211253157868178;83993,18736,20476,21834,16871,211468!GO:0021984;adenohypophysis development;0.0211253157868178;18736!GO:0006109;regulation of carbohydrate metabolic process;0.0211253157868178;18736!GO:0021522;spinal cord motor neuron differentiation;0.0211253157868178;16871!GO:0048701;embryonic cranial skeleton morphogenesis;0.0211253157868178;14683!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0211253157868178;14683!GO:0021517;ventral spinal cord development;0.0211253157868178;16871!GO:0044451;nucleoplasm part;0.0221721459452071;18736,20476,16871!GO:0003677;DNA binding;0.0222761548361811;83993,18736,20476,21834,16871!GO:0045744;negative regulation of G-protein coupled receptor protein signaling pathway;0.0222761548361811;380714!GO:0008340;determination of adult life span;0.0222761548361811;18736!GO:0045669;positive regulation of osteoblast differentiation;0.0222761548361811;14683!GO:0007191;dopamine receptor, adenylate cyclase activating pathway;0.0222761548361811;14683!GO:0021515;cell differentiation in spinal cord;0.0222761548361811;16871!GO:0005654;nucleoplasm;0.0228968227183673;18736,20476,16871!GO:0048856;anatomical structure development;0.0238193328862061;83993,18736,14683,21834,16871!GO:0032502;developmental process;0.0238193328862061;83993,18736,14683,20476,21834,16871!GO:0009886;post-embryonic morphogenesis;0.0238193328862061;14683!GO:0001958;endochondral ossification;0.0238193328862061;14683!GO:0000160;two-component signal transduction system (phosphorelay);0.0254819134731916;211468!GO:0008045;motor axon guidance;0.0254819134731916;16871!GO:0048009;insulin-like growth factor receptor signaling pathway;0.0254819134731916;18736!GO:0006020;inositol metabolic process;0.0254819134731916;18736!GO:0007420;brain development;0.026621305295221;83993,18736!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0269882116123206;83993,18736,20476,21834,16871,211468!GO:0004673;protein histidine kinase activity;0.0269882116123206;211468!GO:0010259;multicellular organismal aging;0.0269882116123206;18736!GO:0007399;nervous system development;0.0275084067601556;83993,18736,16871!GO:0048704;embryonic skeletal morphogenesis;0.029003590036877;14683!GO:0031981;nuclear lumen;0.0307770382413672;18736,20476,16871!GO:0045667;regulation of osteoblast differentiation;0.0307770382413672;14683!GO:0030097;hemopoiesis;0.0307770382413672;18736,14683!GO:0048513;organ development;0.0320697550064008;83993,18736,14683,21834!GO:0045639;positive regulation of myeloid cell differentiation;0.0320697550064008;14683!GO:0021510;spinal cord development;0.0320697550064008;16871!GO:0035116;embryonic hindlimb morphogenesis;0.0338069629820718;14683!GO:0016775;phosphotransferase activity, nitrogenous group as acceptor;0.0338069629820718;211468!GO:0048534;hemopoietic or lymphoid organ development;0.0354718434540506;18736,14683!GO:0045670;regulation of osteoclast differentiation;0.0354718434540506;14683!GO:0048706;embryonic skeletal development;0.0374431685213606;14683!GO:0043233;organelle lumen;0.0377593851977914;18736,20476,16871!GO:0031974;membrane-enclosed lumen;0.0377593851977914;18736,20476,16871!GO:0002520;immune system development;0.0387961186000068;18736,14683!GO:0007212;dopamine receptor signaling pathway;0.0393181365829893;14683!GO:0008277;regulation of G-protein coupled receptor protein signaling pathway;0.0393181365829893;380714!GO:0002761;regulation of myeloid leukocyte differentiation;0.0393181365829893;14683!GO:0017157;regulation of exocytosis;0.0393181365829893;380714!GO:0017137;Rab GTPase binding;0.0411022280316904;380714!GO:0017156;calcium ion-dependent exocytosis;0.0424588572380158;380714!GO:0030316;osteoclast differentiation;0.0424588572380158;14683!GO:0040018;positive regulation of multicellular organism growth;0.0462383828423891;18736!GO:0043234;protein complex;0.0462383828423891;18736,14683,20476,16871!GO:0048705;skeletal morphogenesis;0.0462383828423891;14683!GO:0035137;hindlimb morphogenesis;0.0462383828423891;14683!GO:0001708;cell fate specification;0.0462383828423891;18736!GO:0019319;hexose biosynthetic process;0.0462383828423891;18736!GO:0046165;alcohol biosynthetic process;0.0493702570149621;18736!GO:0046364;monosaccharide biosynthetic process;0.0493702570149621;18736! | |gostat_on_MCL_coexpression=GO:0050794;regulation of cellular process;0.00590710375771117;83993,245684,16871,211468,18736,380714,14683,20476,21834!GO:0050789;regulation of biological process;0.00590710375771117;83993,245684,16871,211468,18736,380714,14683,20476,21834!GO:0021983;pituitary gland development;0.00590710375771117;83993,18736!GO:0021536;diencephalon development;0.00590710375771117;83993,18736!GO:0065007;biological regulation;0.00590710375771117;83993,245684,16871,211468,18736,380714,14683,20476,21834!GO:0003700;transcription factor activity;0.00590710375771117;83993,18736,20476,21834,16871!GO:0043565;sequence-specific DNA binding;0.00642647008083665;18736,20476,21834,16871!GO:0045944;positive regulation of transcription from RNA polymerase II promoter;0.0112185472859472;83993,18736,21834!GO:0007417;central nervous system development;0.0112364024618341;83993,18736,16871!GO:0045893;positive regulation of transcription, DNA-dependent;0.0112364024618341;83993,18736,21834!GO:0035270;endocrine system development;0.0112364024618341;83993,18736!GO:0006355;regulation of transcription, DNA-dependent;0.0112364024618341;83993,18736,20476,21834,16871,211468!GO:0006351;transcription, DNA-dependent;0.0112364024618341;83993,18736,20476,21834,16871,211468!GO:0032774;RNA biosynthetic process;0.0112364024618341;83993,18736,20476,21834,16871,211468!GO:0045449;regulation of transcription;0.0112364024618341;83993,18736,20476,21834,16871,211468!GO:0032962;positive regulation of inositol trisphosphate biosynthetic process;0.0112364024618341;18736!GO:0040032;post-embryonic body morphogenesis;0.0112364024618341;14683!GO:0032958;inositol phosphate biosynthetic process;0.0112364024618341;18736!GO:0032960;regulation of inositol trisphosphate biosynthetic process;0.0112364024618341;18736!GO:0032959;inositol trisphosphate biosynthetic process;0.0112364024618341;18736!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0112364024618341;83993,18736,20476,21834,16871,211468!GO:0045941;positive regulation of transcription;0.0112364024618341;83993,18736,21834!GO:0006350;transcription;0.0112364024618341;83993,18736,20476,21834,16871,211468!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0112364024618341;83993,18736,21834!GO:0010468;regulation of gene expression;0.0124911522910315;83993,18736,20476,21834,16871,211468!GO:0048522;positive regulation of cellular process;0.0124911522910315;83993,18736,14683,21834!GO:0048732;gland development;0.0128309556366026;83993,18736!GO:0031323;regulation of cellular metabolic process;0.0128309556366026;83993,18736,20476,21834,16871,211468!GO:0009966;regulation of signal transduction;0.0128309556366026;380714,18736,245684!GO:0007275;multicellular organismal development;0.0128309556366026;83993,18736,14683,20476,21834,16871!GO:0021526;medial motor column neuron differentiation;0.0128309556366026;16871!GO:0006021;inositol biosynthetic process;0.0128309556366026;18736!GO:0043647;inositol phosphate metabolic process;0.0128309556366026;18736!GO:0032957;inositol trisphosphate metabolic process;0.0128309556366026;18736!GO:0060133;somatotropin secreting cell development;0.0128309556366026;18736!GO:0019222;regulation of metabolic process;0.0128309556366026;83993,18736,20476,21834,16871,211468!GO:0031325;positive regulation of cellular metabolic process;0.0128309556366026;83993,18736,21834!GO:0016070;RNA metabolic process;0.0138703516458522;83993,18736,20476,21834,16871,211468!GO:0009893;positive regulation of metabolic process;0.0138703516458522;83993,18736,21834!GO:0048518;positive regulation of biological process;0.0138703516458522;83993,18736,14683,21834!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.0147857581625108;83993,18736,21834!GO:0030900;forebrain development;0.0148460829282235;83993,18736!GO:0045165;cell fate commitment;0.0148460829282235;83993,18736!GO:0060126;somatotropin secreting cell differentiation;0.0148460829282235;18736!GO:0021523;somatic motor neuron differentiation;0.0148460829282235;16871!GO:0004887;thyroid hormone receptor activity;0.0148460829282235;21834!GO:0043567;regulation of insulin-like growth factor receptor signaling pathway;0.0148460829282235;18736!GO:0005667;transcription factor complex;0.0164725702998602;18736,20476,16871!GO:0006366;transcription from RNA polymerase II promoter;0.0165816177594602;83993,18736,21834!GO:0017158;regulation of calcium ion-dependent exocytosis;0.0172982678649299;380714!GO:0045913;positive regulation of carbohydrate metabolic process;0.0172982678649299;18736!GO:0045672;positive regulation of osteoclast differentiation;0.0172982678649299;14683!GO:0043255;regulation of carbohydrate biosynthetic process;0.0172982678649299;18736!GO:0048731;system development;0.0172982678649299;83993,18736,14683,21834,16871!GO:0002521;leukocyte differentiation;0.0194933648973085;18736,14683!GO:0000155;two-component sensor activity;0.0202358494253453;211468!GO:0010171;body morphogenesis;0.0202358494253453;14683!GO:0019899;enzyme binding;0.0202358494253453;380714,245684!GO:0005515;protein binding;0.0211253157868178;22094,83993,380714,18736,70615,20476,245684,21834!GO:0010467;gene expression;0.0211253157868178;83993,18736,20476,21834,16871,211468!GO:0021984;adenohypophysis development;0.0211253157868178;18736!GO:0006109;regulation of carbohydrate metabolic process;0.0211253157868178;18736!GO:0021522;spinal cord motor neuron differentiation;0.0211253157868178;16871!GO:0048701;embryonic cranial skeleton morphogenesis;0.0211253157868178;14683!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0211253157868178;14683!GO:0021517;ventral spinal cord development;0.0211253157868178;16871!GO:0044451;nucleoplasm part;0.0221721459452071;18736,20476,16871!GO:0003677;DNA binding;0.0222761548361811;83993,18736,20476,21834,16871!GO:0045744;negative regulation of G-protein coupled receptor protein signaling pathway;0.0222761548361811;380714!GO:0008340;determination of adult life span;0.0222761548361811;18736!GO:0045669;positive regulation of osteoblast differentiation;0.0222761548361811;14683!GO:0007191;dopamine receptor, adenylate cyclase activating pathway;0.0222761548361811;14683!GO:0021515;cell differentiation in spinal cord;0.0222761548361811;16871!GO:0005654;nucleoplasm;0.0228968227183673;18736,20476,16871!GO:0048856;anatomical structure development;0.0238193328862061;83993,18736,14683,21834,16871!GO:0032502;developmental process;0.0238193328862061;83993,18736,14683,20476,21834,16871!GO:0009886;post-embryonic morphogenesis;0.0238193328862061;14683!GO:0001958;endochondral ossification;0.0238193328862061;14683!GO:0000160;two-component signal transduction system (phosphorelay);0.0254819134731916;211468!GO:0008045;motor axon guidance;0.0254819134731916;16871!GO:0048009;insulin-like growth factor receptor signaling pathway;0.0254819134731916;18736!GO:0006020;inositol metabolic process;0.0254819134731916;18736!GO:0007420;brain development;0.026621305295221;83993,18736!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0269882116123206;83993,18736,20476,21834,16871,211468!GO:0004673;protein histidine kinase activity;0.0269882116123206;211468!GO:0010259;multicellular organismal aging;0.0269882116123206;18736!GO:0007399;nervous system development;0.0275084067601556;83993,18736,16871!GO:0048704;embryonic skeletal morphogenesis;0.029003590036877;14683!GO:0031981;nuclear lumen;0.0307770382413672;18736,20476,16871!GO:0045667;regulation of osteoblast differentiation;0.0307770382413672;14683!GO:0030097;hemopoiesis;0.0307770382413672;18736,14683!GO:0048513;organ development;0.0320697550064008;83993,18736,14683,21834!GO:0045639;positive regulation of myeloid cell differentiation;0.0320697550064008;14683!GO:0021510;spinal cord development;0.0320697550064008;16871!GO:0035116;embryonic hindlimb morphogenesis;0.0338069629820718;14683!GO:0016775;phosphotransferase activity, nitrogenous group as acceptor;0.0338069629820718;211468!GO:0048534;hemopoietic or lymphoid organ development;0.0354718434540506;18736,14683!GO:0045670;regulation of osteoclast differentiation;0.0354718434540506;14683!GO:0048706;embryonic skeletal development;0.0374431685213606;14683!GO:0043233;organelle lumen;0.0377593851977914;18736,20476,16871!GO:0031974;membrane-enclosed lumen;0.0377593851977914;18736,20476,16871!GO:0002520;immune system development;0.0387961186000068;18736,14683!GO:0007212;dopamine receptor signaling pathway;0.0393181365829893;14683!GO:0008277;regulation of G-protein coupled receptor protein signaling pathway;0.0393181365829893;380714!GO:0002761;regulation of myeloid leukocyte differentiation;0.0393181365829893;14683!GO:0017157;regulation of exocytosis;0.0393181365829893;380714!GO:0017137;Rab GTPase binding;0.0411022280316904;380714!GO:0017156;calcium ion-dependent exocytosis;0.0424588572380158;380714!GO:0030316;osteoclast differentiation;0.0424588572380158;14683!GO:0040018;positive regulation of multicellular organism growth;0.0462383828423891;18736!GO:0043234;protein complex;0.0462383828423891;18736,14683,20476,16871!GO:0048705;skeletal morphogenesis;0.0462383828423891;14683!GO:0035137;hindlimb morphogenesis;0.0462383828423891;14683!GO:0001708;cell fate specification;0.0462383828423891;18736!GO:0019319;hexose biosynthetic process;0.0462383828423891;18736!GO:0046165;alcohol biosynthetic process;0.0493702570149621;18736!GO:0046364;monosaccharide biosynthetic process;0.0493702570149621;18736! | ||
|ontology_enrichment_celltype= | |||
|ontology_enrichment_disease= | |||
|ontology_enrichment_uberon=UBERON:0000007!4.51e-70!8;UBERON:0003296!4.51e-70!8;UBERON:0010133!4.51e-70!8;UBERON:0001894!4.68e-56!10;UBERON:0006222!4.68e-56!10;UBERON:0002780!3.32e-14!39;UBERON:0001890!3.32e-14!39;UBERON:0006240!3.32e-14!39;UBERON:0003080!7.68e-14!40;UBERON:0002616!5.50e-12!46;UBERON:0000955!1.01e-11!47;UBERON:0006238!1.01e-11!47;UBERON:0003056!3.16e-11!49;UBERON:0001049!1.48e-10!52;UBERON:0005068!1.48e-10!52;UBERON:0006241!1.48e-10!52;UBERON:0007135!1.48e-10!52;UBERON:0000073!3.79e-10!54;UBERON:0002368!4.35e-09!60;UBERON:0002346!1.73e-08!64;UBERON:0003075!1.73e-08!64;UBERON:0007284!1.73e-08!64;UBERON:0002530!2.37e-08!65;UBERON:0000949!1.72e-07!72;UBERON:0010371!2.22e-07!73;UBERON:0001017!2.22e-07!73;UBERON:0001016!3.61e-07!75 | |||
}} | }} |
Revision as of 18:32, 11 October 2012
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0050794 | regulation of cellular process | 0.00590710375771117 |
GO:0050789 | regulation of biological process | 0.00590710375771117 |
GO:0021983 | pituitary gland development | 0.00590710375771117 |
GO:0021536 | diencephalon development | 0.00590710375771117 |
GO:0065007 | biological regulation | 0.00590710375771117 |
GO:0003700 | transcription factor activity | 0.00590710375771117 |
GO:0043565 | sequence-specific DNA binding | 0.00642647008083665 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 0.0112185472859472 |
GO:0007417 | central nervous system development | 0.0112364024618341 |
GO:0045893 | positive regulation of transcription, DNA-dependent | 0.0112364024618341 |
GO:0035270 | endocrine system development | 0.0112364024618341 |
GO:0006355 | regulation of transcription, DNA-dependent | 0.0112364024618341 |
GO:0006351 | transcription, DNA-dependent | 0.0112364024618341 |
GO:0032774 | RNA biosynthetic process | 0.0112364024618341 |
GO:0045449 | regulation of transcription | 0.0112364024618341 |
GO:0032962 | positive regulation of inositol trisphosphate biosynthetic process | 0.0112364024618341 |
GO:0040032 | post-embryonic body morphogenesis | 0.0112364024618341 |
GO:0032958 | inositol phosphate biosynthetic process | 0.0112364024618341 |
GO:0032960 | regulation of inositol trisphosphate biosynthetic process | 0.0112364024618341 |
GO:0032959 | inositol trisphosphate biosynthetic process | 0.0112364024618341 |
GO:0019219 | regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 0.0112364024618341 |
GO:0045941 | positive regulation of transcription | 0.0112364024618341 |
GO:0006350 | transcription | 0.0112364024618341 |
GO:0045935 | positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 0.0112364024618341 |
GO:0010468 | regulation of gene expression | 0.0124911522910315 |
GO:0048522 | positive regulation of cellular process | 0.0124911522910315 |
GO:0048732 | gland development | 0.0128309556366026 |
GO:0031323 | regulation of cellular metabolic process | 0.0128309556366026 |
GO:0009966 | regulation of signal transduction | 0.0128309556366026 |
GO:0007275 | multicellular organismal development | 0.0128309556366026 |
GO:0021526 | medial motor column neuron differentiation | 0.0128309556366026 |
GO:0006021 | inositol biosynthetic process | 0.0128309556366026 |
GO:0043647 | inositol phosphate metabolic process | 0.0128309556366026 |
GO:0032957 | inositol trisphosphate metabolic process | 0.0128309556366026 |
GO:0060133 | somatotropin secreting cell development | 0.0128309556366026 |
GO:0019222 | regulation of metabolic process | 0.0128309556366026 |
GO:0031325 | positive regulation of cellular metabolic process | 0.0128309556366026 |
GO:0016070 | RNA metabolic process | 0.0138703516458522 |
GO:0009893 | positive regulation of metabolic process | 0.0138703516458522 |
GO:0048518 | positive regulation of biological process | 0.0138703516458522 |
GO:0006357 | regulation of transcription from RNA polymerase II promoter | 0.0147857581625108 |
GO:0030900 | forebrain development | 0.0148460829282235 |
GO:0045165 | cell fate commitment | 0.0148460829282235 |
GO:0060126 | somatotropin secreting cell differentiation | 0.0148460829282235 |
GO:0021523 | somatic motor neuron differentiation | 0.0148460829282235 |
GO:0004887 | thyroid hormone receptor activity | 0.0148460829282235 |
GO:0043567 | regulation of insulin-like growth factor receptor signaling pathway | 0.0148460829282235 |
GO:0005667 | transcription factor complex | 0.0164725702998602 |
GO:0006366 | transcription from RNA polymerase II promoter | 0.0165816177594602 |
GO:0017158 | regulation of calcium ion-dependent exocytosis | 0.0172982678649299 |
GO:0045913 | positive regulation of carbohydrate metabolic process | 0.0172982678649299 |
GO:0045672 | positive regulation of osteoclast differentiation | 0.0172982678649299 |
GO:0043255 | regulation of carbohydrate biosynthetic process | 0.0172982678649299 |
GO:0048731 | system development | 0.0172982678649299 |
GO:0002521 | leukocyte differentiation | 0.0194933648973085 |
GO:0000155 | two-component sensor activity | 0.0202358494253453 |
GO:0010171 | body morphogenesis | 0.0202358494253453 |
GO:0019899 | enzyme binding | 0.0202358494253453 |
GO:0005515 | protein binding | 0.0211253157868178 |
GO:0010467 | gene expression | 0.0211253157868178 |
GO:0021984 | adenohypophysis development | 0.0211253157868178 |
GO:0006109 | regulation of carbohydrate metabolic process | 0.0211253157868178 |
GO:0021522 | spinal cord motor neuron differentiation | 0.0211253157868178 |
GO:0048701 | embryonic cranial skeleton morphogenesis | 0.0211253157868178 |
GO:0002763 | positive regulation of myeloid leukocyte differentiation | 0.0211253157868178 |
GO:0021517 | ventral spinal cord development | 0.0211253157868178 |
GO:0044451 | nucleoplasm part | 0.0221721459452071 |
GO:0003677 | DNA binding | 0.0222761548361811 |
GO:0045744 | negative regulation of G-protein coupled receptor protein signaling pathway | 0.0222761548361811 |
GO:0008340 | determination of adult life span | 0.0222761548361811 |
GO:0045669 | positive regulation of osteoblast differentiation | 0.0222761548361811 |
GO:0007191 | dopamine receptor, adenylate cyclase activating pathway | 0.0222761548361811 |
GO:0021515 | cell differentiation in spinal cord | 0.0222761548361811 |
GO:0005654 | nucleoplasm | 0.0228968227183673 |
GO:0048856 | anatomical structure development | 0.0238193328862061 |
GO:0032502 | developmental process | 0.0238193328862061 |
GO:0009886 | post-embryonic morphogenesis | 0.0238193328862061 |
GO:0001958 | endochondral ossification | 0.0238193328862061 |
GO:0000160 | two-component signal transduction system (phosphorelay) | 0.0254819134731916 |
GO:0008045 | motor axon guidance | 0.0254819134731916 |
GO:0048009 | insulin-like growth factor receptor signaling pathway | 0.0254819134731916 |
GO:0006020 | inositol metabolic process | 0.0254819134731916 |
GO:0007420 | brain development | 0.026621305295221 |
GO:0006139 | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 0.0269882116123206 |
GO:0004673 | protein histidine kinase activity | 0.0269882116123206 |
GO:0010259 | multicellular organismal aging | 0.0269882116123206 |
GO:0007399 | nervous system development | 0.0275084067601556 |
GO:0048704 | embryonic skeletal morphogenesis | 0.029003590036877 |
GO:0031981 | nuclear lumen | 0.0307770382413672 |
GO:0045667 | regulation of osteoblast differentiation | 0.0307770382413672 |
GO:0030097 | hemopoiesis | 0.0307770382413672 |
GO:0048513 | organ development | 0.0320697550064008 |
GO:0045639 | positive regulation of myeloid cell differentiation | 0.0320697550064008 |
GO:0021510 | spinal cord development | 0.0320697550064008 |
GO:0035116 | embryonic hindlimb morphogenesis | 0.0338069629820718 |
GO:0016775 | phosphotransferase activity, nitrogenous group as acceptor | 0.0338069629820718 |
GO:0048534 | hemopoietic or lymphoid organ development | 0.0354718434540506 |
GO:0045670 | regulation of osteoclast differentiation | 0.0354718434540506 |
GO:0048706 | embryonic skeletal development | 0.0374431685213606 |
GO:0043233 | organelle lumen | 0.0377593851977914 |
GO:0031974 | membrane-enclosed lumen | 0.0377593851977914 |
GO:0002520 | immune system development | 0.0387961186000068 |
GO:0007212 | dopamine receptor signaling pathway | 0.0393181365829893 |
GO:0008277 | regulation of G-protein coupled receptor protein signaling pathway | 0.0393181365829893 |
GO:0002761 | regulation of myeloid leukocyte differentiation | 0.0393181365829893 |
GO:0017157 | regulation of exocytosis | 0.0393181365829893 |
GO:0017137 | Rab GTPase binding | 0.0411022280316904 |
GO:0017156 | calcium ion-dependent exocytosis | 0.0424588572380158 |
GO:0030316 | osteoclast differentiation | 0.0424588572380158 |
GO:0040018 | positive regulation of multicellular organism growth | 0.0462383828423891 |
GO:0043234 | protein complex | 0.0462383828423891 |
GO:0048705 | skeletal morphogenesis | 0.0462383828423891 |
GO:0035137 | hindlimb morphogenesis | 0.0462383828423891 |
GO:0001708 | cell fate specification | 0.0462383828423891 |
GO:0019319 | hexose biosynthetic process | 0.0462383828423891 |
GO:0046165 | alcohol biosynthetic process | 0.0493702570149621 |
GO:0046364 | monosaccharide biosynthetic process | 0.0493702570149621 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
Ontology term | p-value | n |
---|---|---|
pituitary gland | 4.51e-70 | 8 |
gland of diencephalon | 4.51e-70 | 8 |
neuroendocrine gland | 4.51e-70 | 8 |
diencephalon | 4.68e-56 | 10 |
future diencephalon | 4.68e-56 | 10 |
regional part of forebrain | 3.32e-14 | 39 |
forebrain | 3.32e-14 | 39 |
future forebrain | 3.32e-14 | 39 |
anterior neural tube | 7.68e-14 | 40 |
regional part of brain | 5.50e-12 | 46 |
brain | 1.01e-11 | 47 |
future brain | 1.01e-11 | 47 |
pre-chordal neural plate | 3.16e-11 | 49 |
neural tube | 1.48e-10 | 52 |
neural rod | 1.48e-10 | 52 |
future spinal cord | 1.48e-10 | 52 |
neural keel | 1.48e-10 | 52 |
regional part of nervous system | 3.79e-10 | 54 |
endocrine gland | 4.35e-09 | 60 |
neurectoderm | 1.73e-08 | 64 |
neural plate | 1.73e-08 | 64 |
presumptive neural plate | 1.73e-08 | 64 |
gland | 2.37e-08 | 65 |
endocrine system | 1.72e-07 | 72 |
ecto-epithelium | 2.22e-07 | 73 |
central nervous system | 2.22e-07 | 73 |
nervous system | 3.61e-07 | 75 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
{{{tfbs_overrepresentation_jaspar}}} |