Personal tools

Coexpression cluster:C2887

From FANTOM5_SSTAR

Revision as of 14:29, 21 May 2012 by Autoedit (talk | contribs)
Jump to: navigation, search


Full id: C2887_mesodermal_Dendritic_acute_thymus_spinal_heart_seminal



Phase1 CAGE Peaks

Hg19::chr7:158937551..158937569,-p1@VIPR2
Hg19::chr7:158937577..158937594,-p4@VIPR2
Hg19::chr7:158937598..158937613,-p3@VIPR2
Hg19::chr7:158937633..158937652,-p2@VIPR2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism3.09e-63115
neural tube2.27e-2557
neural rod2.27e-2557
future spinal cord2.27e-2557
neural keel2.27e-2557
central nervous system1.21e-2282
regional part of nervous system4.31e-2194
nervous system4.31e-2194
anterior neural tube9.35e-2142
regional part of brain1.48e-2059
regional part of forebrain3.40e-2041
forebrain3.40e-2041
future forebrain3.40e-2041
neural plate1.19e-1986
presumptive neural plate1.19e-1986
brain1.42e-1969
future brain1.42e-1969
telencephalon3.32e-1834
gray matter5.78e-1834
brain grey matter5.78e-1834
neurectoderm7.65e-1890
regional part of telencephalon1.65e-1733
cerebral hemisphere4.59e-1732
neocortex4.78e-1520
cerebral cortex5.39e-1525
pallium5.39e-1525
regional part of cerebral cortex1.37e-1422
pre-chordal neural plate7.15e-1461
anterior region of body1.98e-11129
craniocervical region1.98e-11129
head4.12e-10123
ectoderm-derived structure8.25e-10169
ectoderm4.33e-09173
presumptive ectoderm4.33e-09173
larynx5.00e-099
upper respiratory tract1.32e-0719
organ part6.71e-07219


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.