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MCL coexpression mm9:1878

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:127162428..127162443,+p1@Tac2
Mm9::chrX:155897065..155897097,+p3@Mtap7d2
Mm9::chrX:155897099..155897125,+p7@Mtap7d2
Mm9::chrX:155897131..155897146,+p6@Mtap7d2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0007217tachykinin signaling pathway0.00131485235303786
GO:0007218neuropeptide signaling pathway0.01840793294253



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
ectodermal cell5.71e-0944
neurectodermal cell5.71e-0944
neuron6.50e-0933
neuronal stem cell6.50e-0933
neuroblast6.50e-0933
electrically signaling cell6.50e-0933
neural cell1.30e-0843
electrically responsive cell5.35e-0839
electrically active cell5.35e-0839
non-terminally differentiated cell5.92e-0849

Uber Anatomy
Ontology termp-valuen
nervous system1.10e-2275
structure with developmental contribution from neural crest4.38e-2292
central nervous system4.52e-2273
ectoderm-derived structure3.47e-1995
ectoderm3.47e-1995
presumptive ectoderm3.47e-1995
neurectoderm6.60e-1964
neural plate6.60e-1964
presumptive neural plate6.60e-1964
regional part of nervous system1.33e-1754
neural tube1.94e-1652
neural rod1.94e-1652
future spinal cord1.94e-1652
neural keel1.94e-1652
ecto-epithelium7.59e-1573
brain1.49e-1447
future brain1.49e-1447
regional part of brain6.19e-1446
pre-chordal neural plate2.62e-1249
anterior neural tube1.83e-1140
regional part of forebrain7.55e-1139
forebrain7.55e-1139
future forebrain7.55e-1139
gray matter1.22e-0834
multi-cellular organism1.94e-07333
brain grey matter4.91e-0729
regional part of telencephalon4.91e-0729
telencephalon4.91e-0729


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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