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MCL coexpression mm9:845

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Phase1 CAGE Peaks

 Short description
Mm9::chr2:71367605..71367621,+p9@Dlx1
Mm9::chr2:71367646..71367658,+p11@Dlx1
Mm9::chr2:71367712..71367725,-p@chr2:71367712..71367725
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Mm9::chr2:71367855..71367864,+p6@Dlx1
Mm9::chr2:71367871..71367898,+p1@Dlx1
Mm9::chr2:71384401..71384424,-p3@Dlx2
Mm9::chr2:71384425..71384456,-p4@Dlx2
Mm9::chr2:71384458..71384526,-p2@Dlx2
Mm9::chr3:103379198..103379209,+p2@Syt6


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0003682chromatin binding0.0100113843144172
GO:0048306calcium-dependent protein binding0.0377534594233227
GO:0005667transcription factor complex0.0377534594233227
GO:0043565sequence-specific DNA binding0.0377534594233227
GO:0007340acrosome reaction0.0377534594233227
GO:0003727single-stranded RNA binding0.0377534594233227
GO:0044451nucleoplasm part0.0377534594233227
GO:0005654nucleoplasm0.0377534594233227
GO:0017156calcium ion-dependent exocytosis0.039472660718551
GO:0031981nuclear lumen0.039472660718551
GO:0043524negative regulation of neuron apoptosis0.039472660718551
GO:0031974membrane-enclosed lumen0.041487927027033
GO:0043233organelle lumen0.041487927027033
GO:0043523regulation of neuron apoptosis0.0432655166342465
GO:0003700transcription factor activity0.0432655166342465
GO:0051402neuron apoptosis0.0447989412981176
GO:0007338single fertilization0.0454849411957286
GO:0009566fertilization0.0497183098655478
GO:0044428nuclear part0.0497183098655478
GO:0008021synaptic vesicle0.0499450898651755



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
ectoderm-derived structure6.70e-1695
ectoderm6.70e-1695
presumptive ectoderm6.70e-1695
nervous system7.94e-1475
central nervous system6.47e-1373
pre-chordal neural plate1.00e-1249
ecto-epithelium5.07e-1273
brain grey matter2.13e-1129
regional part of telencephalon2.13e-1129
telencephalon2.13e-1129
peripheral nervous system5.44e-1111
neurectoderm6.93e-1164
neural plate6.93e-1164
presumptive neural plate6.93e-1164
anterior neural tube1.38e-1040
regional part of forebrain2.58e-1039
forebrain2.58e-1039
future forebrain2.58e-1039
autonomic nervous system3.24e-109
brain8.22e-1047
future brain8.22e-1047
regional part of brain4.23e-0946
gray matter1.25e-0834
neural tube4.61e-0752
neural rod4.61e-0752
future spinal cord4.61e-0752
neural keel4.61e-0752
regional part of nervous system5.07e-0754
cerebral cortex7.49e-0721
cerebral hemisphere7.49e-0721
pallium7.49e-0721


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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