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Coexpression cluster:C444

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Full id: C444_CD14_trachea_tonsil_tongue_throat_salivary_gall



Phase1 CAGE Peaks

Hg19::chr11:1263090..1263101,+p@chr11:1263090..1263101
+
Hg19::chr11:1267107..1267120,+p4@MUC5B
Hg19::chr11:1267285..1267314,+p14@MUC5B
Hg19::chr11:1283125..1283153,+p@chr11:1283125..1283153
+
Hg19::chr11:1283367..1283377,+p@chr11:1283367..1283377
+
Hg19::chr12:10998477..10998481,-p@chr12:10998477..10998481
-
Hg19::chr18:108531..108547,+p@chr18:108531..108547
+
Hg19::chr20:31611261..31611291,+p1@BPIFB6
Hg19::chr20:31611311..31611316,+p11@BPIFB6
Hg19::chr20:31611317..31611336,+p2@BPIFB6
Hg19::chr20:31611463..31611474,+p3@BPIFB6
Hg19::chr20:31830997..31831004,+p@chr20:31830997..31831004
+
Hg19::chr20:31894723..31894752,+p@chr20:31894723..31894752
+
Hg19::chr20:31897591..31897596,+p@chr20:31897591..31897596
+
Hg19::chr20:31897621..31897629,+p@chr20:31897621..31897629
+
Hg19::chr20:31897630..31897644,+p@chr20:31897630..31897644
+
Hg19::chr22:50643240..50643252,+p@chr22:50643240..50643252
+
Hg19::chr9:138415783..138415790,+p@chr9:138415783..138415790
+
Hg19::chr9:138418185..138418192,+p@chr9:138418185..138418192
+
Hg19::chr9:138418232..138418239,+p@chr9:138418232..138418239
+
Hg19::chr9:138418242..138418256,+p@chr9:138418242..138418256
+
Hg19::chr9:138418258..138418269,+p@chr9:138418258..138418269
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0005201extracellular matrix structural constituent0.0217237725185447
GO:0030414protease inhibitor activity0.023489932885906
GO:0004857enzyme inhibitor activity0.0236076769103968
GO:0007155cell adhesion0.033910279053338
GO:0022610biological adhesion0.033910279053338



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
bone marrow9.24e-1480
bone element1.02e-1386
immune system6.92e-13115
skeletal element5.08e-12101
skeletal system5.08e-12101
hematopoietic system6.01e-11102
blood island6.01e-11102
hemolymphoid system1.03e-09112
organ8.62e-09511
embryo2.41e-07612
adult organism5.35e-07115
germ layer5.81e-07604
embryonic tissue5.81e-07604
presumptive structure5.81e-07604
epiblast (generic)5.81e-07604
multi-cellular organism5.89e-07659
embryonic structure6.77e-07605
developing anatomical structure6.77e-07605


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.