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Coexpression cluster:C2926

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Full id: C2926_small_glioblastoma_chronic_occipital_tridermal_nonsmall_lymphoma



Phase1 CAGE Peaks

Hg19::chr8:60031682..60031710,-p2@TOX
Hg19::chr8:60031762..60031803,-p3@TOX
Hg19::chr8:60031809..60031835,-p4@TOX
Hg19::chr8:60031840..60031869,-p5@TOX


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
central nervous system3.58e-1982
anterior region of body1.66e-18129
craniocervical region1.66e-18129
regional part of nervous system5.08e-1894
nervous system5.08e-1894
neural plate9.35e-1886
presumptive neural plate9.35e-1886
pre-chordal neural plate5.04e-1761
head5.92e-17123
neurectoderm1.02e-1590
adult organism1.50e-15115
neural tube1.53e-1557
neural rod1.53e-1557
future spinal cord1.53e-1557
neural keel1.53e-1557
brain2.68e-1569
future brain2.68e-1569
ectoderm-derived structure2.98e-15169
regional part of forebrain5.30e-1541
forebrain5.30e-1541
future forebrain5.30e-1541
anterior neural tube1.30e-1442
cerebral hemisphere2.69e-1432
telencephalon4.09e-1434
gray matter5.04e-1434
brain grey matter5.04e-1434
ectoderm5.14e-14173
presumptive ectoderm5.14e-14173
regional part of telencephalon1.18e-1333
regional part of brain1.61e-1359
cerebral cortex3.39e-1325
pallium3.39e-1325
regional part of cerebral cortex1.47e-1122
neocortex2.28e-1120
organ part9.69e-07219


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.