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Coexpression cluster:C608

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Full id: C608_Smooth_mesenchymal_hepatic_Olfactory_Ewing_basal_Fibroblast



Phase1 CAGE Peaks

Hg19::chr8:23155120..23155153,-p@chr8:23155120..23155153
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Hg19::chr8:23155270..23155284,-p@chr8:23155270..23155284
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Hg19::chr8:23155299..23155339,-p@chr8:23155299..23155339
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Hg19::chr8:23156379..23156401,-p@chr8:23156379..23156401
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Hg19::chr8:23156447..23156464,-p@chr8:23156447..23156464
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Hg19::chr8:23159569..23159589,-p@chr8:23159569..23159589
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Hg19::chr8:23159605..23159623,-p@chr8:23159605..23159623
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Hg19::chr8:23159627..23159644,-p@chr8:23159627..23159644
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Hg19::chr8:23160831..23160851,-p@chr8:23160831..23160851
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Hg19::chr8:23160879..23160895,-p@chr8:23160879..23160895
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Hg19::chr8:23160901..23160919,-p@chr8:23160901..23160919
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Hg19::chr8:23167261..23167303,-p@chr8:23167261..23167303
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Hg19::chr8:23198609..23198642,-p4@LOXL2
Hg19::chr8:23217696..23217708,-p@chr8:23217696..23217708
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Hg19::chr8:23261625..23261641,-p1@LOXL2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Uber Anatomy
Ontology termp-valuen
vasculature1.13e-1978
vascular system1.13e-1978
cardiovascular system6.83e-16109
vessel7.87e-1668
artery3.76e-1542
arterial blood vessel3.76e-1542
arterial system3.76e-1542
splanchnic layer of lateral plate mesoderm5.91e-1583
circulatory system8.02e-15112
epithelial vesicle1.18e-1478
epithelial tube open at both ends2.39e-1459
blood vessel2.39e-1459
blood vasculature2.39e-1459
vascular cord2.39e-1459
unilaminar epithelium5.80e-14148
epithelial tube1.50e-13117
somite1.75e-1371
presomitic mesoderm1.75e-1371
presumptive segmental plate1.75e-1371
dermomyotome1.75e-1371
trunk paraxial mesoderm1.75e-1371
dense mesenchyme tissue1.93e-1373
skeletal muscle tissue3.67e-1362
striated muscle tissue3.67e-1362
myotome3.67e-1362
paraxial mesoderm4.70e-1372
presumptive paraxial mesoderm4.70e-1372
muscle tissue2.94e-1264
musculature2.94e-1264
musculature of body2.94e-1264
systemic artery1.22e-1133
systemic arterial system1.22e-1133
multilaminar epithelium1.31e-1183
trunk mesenchyme5.55e-11122
mesenchyme7.61e-11160
entire embryonic mesenchyme7.61e-11160
trunk2.41e-07199
aorta3.13e-0721
aortic system3.13e-0721
mesoderm6.42e-07315
mesoderm-derived structure6.42e-07315
presumptive mesoderm6.42e-07315
Disease
Ontology termp-valuen
ovarian cancer1.80e-0914


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.