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MCL coexpression mm9:2102

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Phase1 CAGE Peaks

 Short description
Mm9::chr14:34791937..34791977,-p1@Zfp488
Mm9::chr14:34791987..34791998,-p2@Zfp488
Mm9::chr7:38554745..38554756,-p7@Zfp536
Mm9::chr7:38554763..38554780,-p1@Zfp536


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0048714positive regulation of oligodendrocyte differentiation0.00854560379022112
GO:0048713regulation of oligodendrocyte differentiation0.00854560379022112
GO:0014015positive regulation of gliogenesis0.00854560379022112
GO:0045687positive regulation of glial cell differentiation0.00854560379022112
GO:0014003oligodendrocyte development0.00854560379022112
GO:0045685regulation of glial cell differentiation0.00949381462173878
GO:0014013regulation of gliogenesis0.00949381462173878
GO:0048709oligodendrocyte differentiation0.00949381462173878
GO:0021782glial cell development0.00949381462173878
GO:0010001glial cell differentiation0.0318203804753961
GO:0042063gliogenesis0.0318203804753961
GO:0045597positive regulation of cell differentiation0.0327213510388878
GO:0051094positive regulation of developmental process0.0452779046561311



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
neuron1.12e-1033
neuronal stem cell1.12e-1033
neuroblast1.12e-1033
electrically signaling cell1.12e-1033
autonomic neuron5.37e-089
ectodermal cell5.42e-0844
neurectodermal cell5.42e-0844
neural cell5.61e-0843
electrically responsive cell3.56e-0739
electrically active cell3.56e-0739

Uber Anatomy
Ontology termp-valuen
ectoderm-derived structure1.08e-2395
ectoderm1.08e-2395
presumptive ectoderm1.08e-2395
nervous system3.21e-2075
central nervous system4.48e-2073
neurectoderm1.54e-1964
neural plate1.54e-1964
presumptive neural plate1.54e-1964
ecto-epithelium6.50e-1873
pre-chordal neural plate2.12e-1349
structure with developmental contribution from neural crest2.15e-1392
regional part of nervous system6.41e-1354
neural tube6.85e-1252
neural rod6.85e-1252
future spinal cord6.85e-1252
neural keel6.85e-1252
brain1.84e-0947
future brain1.84e-0947
regional part of brain5.20e-0946
gray matter7.36e-0934
anterior neural tube2.95e-0840
autonomic nervous system5.37e-089
regional part of forebrain9.00e-0839
forebrain9.00e-0839
future forebrain9.00e-0839
peripheral nervous system1.46e-0711
eye2.32e-079
camera-type eye2.32e-079
simple eye2.32e-079
immature eye2.32e-079
ocular region2.32e-079
visual system2.32e-079
face2.32e-079
optic cup2.32e-079
optic vesicle2.32e-079
eye primordium2.32e-079


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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