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Coexpression cluster:C4071

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Full id: C4071_Mast_testicular_CD34_peripheral_skeletal_nonsmall_lung



Phase1 CAGE Peaks

Hg19::chr21:27107323..27107334,-p5@ATP5J
Hg19::chr21:27107346..27107357,-p4@ATP5J
Hg19::chr21:27107359..27107370,-p3@ATP5J


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
central nervous system5.71e-1982
regional part of nervous system1.26e-1894
nervous system1.26e-1894
neurectoderm9.47e-1690
brain1.47e-1569
future brain1.47e-1569
regional part of brain3.86e-1559
neural plate1.58e-1486
presumptive neural plate1.58e-1486
regional part of forebrain1.79e-1441
forebrain1.79e-1441
future forebrain1.79e-1441
neural tube3.01e-1457
neural rod3.01e-1457
future spinal cord3.01e-1457
neural keel3.01e-1457
anterior neural tube7.21e-1442
adult organism1.06e-13115
cerebral hemisphere3.63e-1332
telencephalon6.17e-1334
regional part of telencephalon2.05e-1233
pre-chordal neural plate3.03e-1261
gray matter7.66e-1234
brain grey matter7.66e-1234
regional part of cerebral cortex5.13e-1122
cerebral cortex1.63e-1025
pallium1.63e-1025
neocortex3.15e-1020
ectoderm6.29e-10173
presumptive ectoderm6.29e-10173
anterior region of body4.33e-09129
craniocervical region4.33e-09129
ectoderm-derived structure4.82e-09169
head9.01e-09123


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.