FF:10399-106A3: Difference between revisions
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{{f5samples | {{f5samples | ||
|ancestors_in_anatomy_facet= | |DRA_sample_Accession=CAGE@SAMD00005753 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |accession_numbers=CAGE;DRX007813;DRR008685;DRZ000110;DRZ001495;DRZ011460;DRZ012845 | ||
|ancestors_in_anatomy_facet= | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000766,CL:0000219,CL:0000738,CL:0002087,CL:0000255,CL:0000576 | |||
|ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:2531,DOID:14566,DOID:0060083,DOID:1240,DOID:8692 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100737,FF:0101370,FF:0101035,FF:0101883,FF:0102332,FF:0100740 | |||
|comment= | |comment= | ||
|created_by= | |created_by= | ||
|creation_date= | |creation_date= | ||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |def= | ||
|expression_enrichment_score | |||
|fonse_cell_line=FF:0101035 | |fonse_cell_line=FF:0101035 | ||
|fonse_cell_line_closure=FF:0101035 | |fonse_cell_line_closure=FF:0101035 | ||
| Line 35: | Line 41: | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M5%2529%2520cell%2520line%253aTHP-1%2520%2528fresh%2529.CNhs10722.10399-106A3.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M5%2529%2520cell%2520line%253aTHP-1%2520%2528fresh%2529.CNhs10722.10399-106A3.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M5%2529%2520cell%2520line%253aTHP-1%2520%2528fresh%2529.CNhs10722.10399-106A3.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M5%2529%2520cell%2520line%253aTHP-1%2520%2528fresh%2529.CNhs10722.10399-106A3.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M5%2529%2520cell%2520line%253aTHP-1%2520%2528fresh%2529.CNhs10722.10399-106A3.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10399-106A3 | |id=FF:10399-106A3 | ||
|is_a=EFO:0002091;;FF: | |is_a=EFO:0002091;;FF:0000210;;FF:0101370;;FF:0101883 | ||
|is_obsolete= | |||
|library_id=CNhs10722 | |||
|library_id_phase_based=2:CNhs10722 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10399 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10399 | |||
|name=acute myeloid leukemia (FAB M5) cell line:THP-1 (fresh) | |name=acute myeloid leukemia (FAB M5) cell line:THP-1 (fresh) | ||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
| Line 44: | Line 62: | ||
|profile_rnaseq= | |profile_rnaseq= | ||
|profile_srnaseq= | |profile_srnaseq= | ||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
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| |||
|rna_box=106 | |rna_box=106 | ||
|rna_catalog_number= | |rna_catalog_number= | ||
| Line 57: | Line 78: | ||
|rna_weight_ug=33.13493333 | |rna_weight_ug=33.13493333 | ||
|sample_age=1 | |sample_age=1 | ||
|sample_category=cell lines | |||
|sample_cell_catalog= | |sample_cell_catalog= | ||
|sample_cell_line=THP-1 | |sample_cell_line=THP-1 | ||
| Line 69: | Line 91: | ||
|sample_ethnicity=J | |sample_ethnicity=J | ||
|sample_experimental_condition=FREEZOME | |sample_experimental_condition=FREEZOME | ||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;3.67271113898658e-270!GO:0043227;membrane-bound organelle;2.66035167084493e-244!GO:0043231;intracellular membrane-bound organelle;4.69520012514205e-244!GO:0043226;organelle;1.53234358249845e-230!GO:0043229;intracellular organelle;5.82391193213002e-230!GO:0044422;organelle part;3.40507193650367e-162!GO:0044446;intracellular organelle part;1.78616341544735e-160!GO:0005737;cytoplasm;8.91349091067583e-160!GO:0044237;cellular metabolic process;1.98832043261062e-124!GO:0005634;nucleus;2.89436460185819e-122!GO:0044238;primary metabolic process;1.49265870428932e-120!GO:0044444;cytoplasmic part;1.24938914739859e-119!GO:0032991;macromolecular complex;2.28941732606514e-118!GO:0043170;macromolecule metabolic process;9.80726074314242e-114!GO:0030529;ribonucleoprotein complex;1.77643924625876e-102!GO:0044428;nuclear part;1.68650418681742e-99!GO:0043233;organelle lumen;8.15881016074908e-90!GO:0031974;membrane-enclosed lumen;8.15881016074908e-90!GO:0003723;RNA binding;1.98382670617421e-88!GO:0005739;mitochondrion;7.26187048030206e-74!GO:0043283;biopolymer metabolic process;1.16213246977468e-73!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;7.3632387303445e-70!GO:0010467;gene expression;3.26797563831712e-65!GO:0006396;RNA processing;3.58153004381779e-64!GO:0043234;protein complex;5.65766927792883e-59!GO:0006412;translation;3.8551128658365e-57!GO:0031981;nuclear lumen;4.08790869447905e-57!GO:0005515;protein binding;1.06241335514161e-56!GO:0005840;ribosome;1.18801448486273e-56!GO:0044429;mitochondrial part;1.33056983461252e-52!GO:0006259;DNA metabolic process;2.50533133675701e-51!GO:0016071;mRNA metabolic process;5.75752799855559e-50!GO:0003735;structural constituent of ribosome;6.28474479906995e-50!GO:0031967;organelle envelope;6.89030312517088e-48!GO:0031975;envelope;1.79902646381819e-47!GO:0019538;protein metabolic process;2.52378089797285e-47!GO:0003676;nucleic acid binding;2.73019677020562e-47!GO:0031090;organelle membrane;3.4284640466249e-46!GO:0033036;macromolecule localization;2.5387907446143e-45!GO:0044249;cellular biosynthetic process;3.38294082846329e-45!GO:0009058;biosynthetic process;3.41368088606255e-45!GO:0016043;cellular component organization and biogenesis;1.25134604599407e-44!GO:0008380;RNA splicing;1.2861942201995e-44!GO:0006397;mRNA processing;3.99210482065171e-44!GO:0015031;protein transport;1.0170936159127e-43!GO:0009059;macromolecule biosynthetic process;3.97348612334312e-43!GO:0044260;cellular macromolecule metabolic process;3.97348612334312e-43!GO:0044267;cellular protein metabolic process;5.43662403482002e-43!GO:0033279;ribosomal subunit;2.86712033063136e-42!GO:0045184;establishment of protein localization;1.00684983120481e-41!GO:0008104;protein localization;2.07818885949123e-40!GO:0006996;organelle organization and biogenesis;5.01573809582967e-38!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.21906394813192e-37!GO:0005829;cytosol;1.51215373849663e-37!GO:0065003;macromolecular complex assembly;8.95644012526259e-37!GO:0005654;nucleoplasm;4.78968257728663e-36!GO:0007049;cell cycle;6.50261302051685e-36!GO:0043228;non-membrane-bound organelle;7.25902543184169e-35!GO:0043232;intracellular non-membrane-bound organelle;7.25902543184169e-35!GO:0046907;intracellular transport;1.61873261448548e-34!GO:0016070;RNA metabolic process;7.55044287175966e-34!GO:0005681;spliceosome;1.71553527943719e-33!GO:0005740;mitochondrial envelope;1.87687020650508e-32!GO:0022607;cellular component assembly;3.21141190361014e-31!GO:0006974;response to DNA damage stimulus;9.40819367289012e-31!GO:0006886;intracellular protein transport;1.59774996408844e-30!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.60722748565876e-30!GO:0031966;mitochondrial membrane;4.52372577812328e-30!GO:0019866;organelle inner membrane;7.24483023312786e-30!GO:0005694;chromosome;4.34038430251212e-29!GO:0000166;nucleotide binding;1.78576785505356e-28!GO:0022402;cell cycle process;1.85219134487915e-28!GO:0044451;nucleoplasm part;2.91479200198323e-28!GO:0006281;DNA repair;6.06186414474921e-28!GO:0005743;mitochondrial inner membrane;6.30798768316393e-28!GO:0000278;mitotic cell cycle;3.64231940484055e-27!GO:0051649;establishment of cellular localization;3.78039769894176e-27!GO:0051641;cellular localization;1.57959485628601e-26!GO:0044445;cytosolic part;8.68195128499879e-26!GO:0044427;chromosomal part;2.56318113947333e-25!GO:0006119;oxidative phosphorylation;9.76678421424212e-25!GO:0051276;chromosome organization and biogenesis;1.50700128302357e-24!GO:0022403;cell cycle phase;1.19956903912536e-23!GO:0031980;mitochondrial lumen;1.33179507311805e-23!GO:0005759;mitochondrial matrix;1.33179507311805e-23!GO:0000087;M phase of mitotic cell cycle;2.9635493980212e-22!GO:0044455;mitochondrial membrane part;3.67117667890108e-22!GO:0015935;small ribosomal subunit;4.6674857629914e-22!GO:0007067;mitosis;8.11079311239523e-22!GO:0044265;cellular macromolecule catabolic process;1.76745190158338e-21!GO:0022618;protein-RNA complex assembly;1.8539747564087e-21!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;2.06103946946184e-21!GO:0016817;hydrolase activity, acting on acid anhydrides;2.2192659367344e-21!GO:0015934;large ribosomal subunit;2.53231000783796e-21!GO:0016462;pyrophosphatase activity;3.72489087502659e-21!GO:0051301;cell division;3.83457465486377e-21!GO:0009719;response to endogenous stimulus;5.93690302351466e-21!GO:0016874;ligase activity;6.09071680664689e-21!GO:0006457;protein folding;6.92181897346633e-21!GO:0017111;nucleoside-triphosphatase activity;1.93942650037292e-20!GO:0005730;nucleolus;2.43811853233849e-20!GO:0006260;DNA replication;6.39412231892892e-20!GO:0000279;M phase;7.03904502272756e-20!GO:0043285;biopolymer catabolic process;3.14378927366751e-19!GO:0006325;establishment and/or maintenance of chromatin architecture;7.20008980158086e-19!GO:0005746;mitochondrial respiratory chain;9.53067814812348e-19!GO:0032553;ribonucleotide binding;1.35723946799438e-18!GO:0032555;purine ribonucleotide binding;1.35723946799438e-18!GO:0017076;purine nucleotide binding;1.7787701557594e-18!GO:0044248;cellular catabolic process;1.9459697684215e-18!GO:0009057;macromolecule catabolic process;2.05288122577323e-18!GO:0051186;cofactor metabolic process;2.54842022698232e-18!GO:0006323;DNA packaging;3.43190596110254e-18!GO:0005524;ATP binding;5.37934771900834e-18!GO:0032559;adenyl ribonucleotide binding;1.02442993295295e-17!GO:0006512;ubiquitin cycle;1.57676312653966e-17!GO:0048770;pigment granule;1.92752878422344e-17!GO:0042470;melanosome;1.92752878422344e-17!GO:0030554;adenyl nucleotide binding;2.29310718361098e-17!GO:0012505;endomembrane system;2.96376762083642e-17!GO:0008135;translation factor activity, nucleic acid binding;4.81655065360264e-17!GO:0042254;ribosome biogenesis and assembly;5.98166998457313e-17!GO:0006605;protein targeting;6.12707977030075e-17!GO:0051603;proteolysis involved in cellular protein catabolic process;6.53032259379619e-17!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;8.68821525731877e-17!GO:0006511;ubiquitin-dependent protein catabolic process;9.3958970446286e-17!GO:0019941;modification-dependent protein catabolic process;9.68395616119285e-17!GO:0043632;modification-dependent macromolecule catabolic process;9.68395616119285e-17!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.22284404758421e-16!GO:0000502;proteasome complex (sensu Eukaryota);1.2952172352226e-16!GO:0050136;NADH dehydrogenase (quinone) activity;1.65376273767814e-16!GO:0003954;NADH dehydrogenase activity;1.65376273767814e-16!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.65376273767814e-16!GO:0044257;cellular protein catabolic process;1.76764956215293e-16!GO:0000398;nuclear mRNA splicing, via spliceosome;1.91796641522754e-16!GO:0000375;RNA splicing, via transesterification reactions;1.91796641522754e-16!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;1.91796641522754e-16!GO:0005635;nuclear envelope;4.03603484450571e-16!GO:0005761;mitochondrial ribosome;4.26566920341832e-16!GO:0000313;organellar ribosome;4.26566920341832e-16!GO:0006732;coenzyme metabolic process;9.58446393963278e-16!GO:0016887;ATPase activity;1.0352966811355e-15!GO:0042623;ATPase activity, coupled;1.724671123848e-15!GO:0008134;transcription factor binding;2.00621998048082e-15!GO:0050657;nucleic acid transport;2.34071897279435e-15!GO:0051236;establishment of RNA localization;2.34071897279435e-15!GO:0050658;RNA transport;2.34071897279435e-15!GO:0006913;nucleocytoplasmic transport;2.9447709301844e-15!GO:0006403;RNA localization;4.11330082593728e-15!GO:0051169;nuclear transport;7.1387242624592e-15!GO:0016604;nuclear body;8.04920945453019e-15!GO:0042775;organelle ATP synthesis coupled electron transport;9.4903007002369e-15!GO:0042773;ATP synthesis coupled electron transport;9.4903007002369e-15!GO:0044453;nuclear membrane part;1.05222982238126e-14!GO:0031965;nuclear membrane;1.10274287618242e-14!GO:0051082;unfolded protein binding;1.15411166665851e-14!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.53253230387752e-14!GO:0030964;NADH dehydrogenase complex (quinone);1.53253230387752e-14!GO:0045271;respiratory chain complex I;1.53253230387752e-14!GO:0005747;mitochondrial respiratory chain complex I;1.53253230387752e-14!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;4.60494943003684e-14!GO:0043412;biopolymer modification;4.86142395589412e-14!GO:0051726;regulation of cell cycle;8.47770408442903e-14!GO:0030163;protein catabolic process;8.83994825614226e-14!GO:0006413;translational initiation;8.89263985363255e-14!GO:0005643;nuclear pore;9.0335193945735e-14!GO:0044432;endoplasmic reticulum part;1.08433503963358e-13!GO:0003743;translation initiation factor activity;1.20659514018007e-13!GO:0000074;regulation of progression through cell cycle;1.2471224041032e-13!GO:0006399;tRNA metabolic process;2.22730279930796e-13!GO:0051028;mRNA transport;2.91534285637923e-13!GO:0006333;chromatin assembly or disassembly;5.09078939335213e-13!GO:0004386;helicase activity;5.09078939335213e-13!GO:0000785;chromatin;6.78336339086783e-13!GO:0016568;chromatin modification;8.06498134342331e-13!GO:0065002;intracellular protein transport across a membrane;2.43105766149831e-12!GO:0065004;protein-DNA complex assembly;4.31239129198123e-12!GO:0006446;regulation of translational initiation;4.47135771644625e-12!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;6.10604130020114e-12!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;6.12056221375962e-12!GO:0016607;nuclear speck;6.74787094887671e-12!GO:0006364;rRNA processing;7.8320075205985e-12!GO:0005783;endoplasmic reticulum;8.74875911869666e-12!GO:0046930;pore complex;9.499328300284e-12!GO:0051188;cofactor biosynthetic process;1.0840346730427e-11!GO:0006464;protein modification process;1.1107541040262e-11!GO:0009259;ribonucleotide metabolic process;1.1282442208734e-11!GO:0016072;rRNA metabolic process;1.56550903017718e-11!GO:0008026;ATP-dependent helicase activity;2.83272092829411e-11!GO:0009056;catabolic process;3.26583907382183e-11!GO:0000775;chromosome, pericentric region;3.27257774649389e-11!GO:0006163;purine nucleotide metabolic process;3.30626412233051e-11!GO:0006366;transcription from RNA polymerase II promoter;3.88576969767271e-11!GO:0016192;vesicle-mediated transport;4.04586943255739e-11!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;8.43510928222446e-11!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.01839165043309e-10!GO:0012501;programmed cell death;1.21665468869534e-10!GO:0009055;electron carrier activity;1.22227910178053e-10!GO:0009260;ribonucleotide biosynthetic process;1.24623569762474e-10!GO:0048193;Golgi vesicle transport;1.31925258991809e-10!GO:0017038;protein import;1.33259765277387e-10!GO:0006915;apoptosis;1.34155629351548e-10!GO:0006164;purine nucleotide biosynthetic process;1.5023308348248e-10!GO:0016787;hydrolase activity;1.7072582502483e-10!GO:0005789;endoplasmic reticulum membrane;1.9310527092921e-10!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.94272554314481e-10!GO:0016879;ligase activity, forming carbon-nitrogen bonds;2.20523061064634e-10!GO:0043566;structure-specific DNA binding;2.36801941027555e-10!GO:0009150;purine ribonucleotide metabolic process;2.93687713004897e-10!GO:0016779;nucleotidyltransferase activity;3.17954200237994e-10!GO:0043687;post-translational protein modification;3.24511893245054e-10!GO:0006261;DNA-dependent DNA replication;3.41024269077962e-10!GO:0003712;transcription cofactor activity;3.44088056664933e-10!GO:0009108;coenzyme biosynthetic process;4.30667279405229e-10!GO:0019222;regulation of metabolic process;5.44731602211836e-10!GO:0008639;small protein conjugating enzyme activity;5.92938700836228e-10!GO:0006334;nucleosome assembly;8.1362149432162e-10!GO:0008565;protein transporter activity;8.46313641524943e-10!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;8.50375035403724e-10!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;1.04173970407048e-09!GO:0004812;aminoacyl-tRNA ligase activity;1.04173970407048e-09!GO:0016875;ligase activity, forming carbon-oxygen bonds;1.04173970407048e-09!GO:0009152;purine ribonucleotide biosynthetic process;1.33341914010049e-09!GO:0009199;ribonucleoside triphosphate metabolic process;1.33425783412761e-09!GO:0004842;ubiquitin-protein ligase activity;1.44023057352007e-09!GO:0008219;cell death;1.49220292686012e-09!GO:0016265;death;1.49220292686012e-09!GO:0009141;nucleoside triphosphate metabolic process;1.5192321927354e-09!GO:0050794;regulation of cellular process;1.64768879501983e-09!GO:0030532;small nuclear ribonucleoprotein complex;1.86545909344599e-09!GO:0019787;small conjugating protein ligase activity;1.87357923354817e-09!GO:0043038;amino acid activation;1.9651684975327e-09!GO:0006418;tRNA aminoacylation for protein translation;1.9651684975327e-09!GO:0043039;tRNA aminoacylation;1.9651684975327e-09!GO:0009142;nucleoside triphosphate biosynthetic process;2.12479491327852e-09!GO:0009201;ribonucleoside triphosphate biosynthetic process;2.12479491327852e-09!GO:0015986;ATP synthesis coupled proton transport;2.67654169596849e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;2.67654169596849e-09!GO:0009060;aerobic respiration;2.78874288262491e-09!GO:0005819;spindle;2.97194273897375e-09!GO:0031497;chromatin assembly;2.97983253748259e-09!GO:0003697;single-stranded DNA binding;3.31373403878229e-09!GO:0009205;purine ribonucleoside triphosphate metabolic process;3.79927210006518e-09!GO:0009144;purine nucleoside triphosphate metabolic process;3.79927210006518e-09!GO:0006461;protein complex assembly;4.41169481040915e-09!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;6.51863064991531e-09!GO:0009145;purine nucleoside triphosphate biosynthetic process;6.51863064991531e-09!GO:0019829;cation-transporting ATPase activity;1.07942551656966e-08!GO:0016881;acid-amino acid ligase activity;1.18120089411141e-08!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.32980333256786e-08!GO:0015630;microtubule cytoskeleton;1.37135249650789e-08!GO:0045333;cellular respiration;2.21173619304053e-08!GO:0005657;replication fork;2.22322624235288e-08!GO:0051325;interphase;2.47154815506171e-08!GO:0046034;ATP metabolic process;2.56270959487604e-08!GO:0051329;interphase of mitotic cell cycle;2.62620171616507e-08!GO:0006754;ATP biosynthetic process;3.28240697447677e-08!GO:0006753;nucleoside phosphate metabolic process;3.28240697447677e-08!GO:0051170;nuclear import;4.95411342963833e-08!GO:0031323;regulation of cellular metabolic process;5.40986536698597e-08!GO:0007051;spindle organization and biogenesis;6.0397129188685e-08!GO:0015078;hydrogen ion transmembrane transporter activity;7.27582069076384e-08!GO:0005839;proteasome core complex (sensu Eukaryota);7.68109710356979e-08!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.07784669567752e-07!GO:0032446;protein modification by small protein conjugation;1.12629586082385e-07!GO:0006099;tricarboxylic acid cycle;1.26865471704216e-07!GO:0046356;acetyl-CoA catabolic process;1.26865471704216e-07!GO:0005813;centrosome;1.2794065193457e-07!GO:0000075;cell cycle checkpoint;1.38195885257333e-07!GO:0016567;protein ubiquitination;1.5794128331296e-07!GO:0005815;microtubule organizing center;1.67795205747002e-07!GO:0006606;protein import into nucleus;1.75091322332852e-07!GO:0016469;proton-transporting two-sector ATPase complex;2.72245792196901e-07!GO:0005794;Golgi apparatus;2.92816723819308e-07!GO:0004298;threonine endopeptidase activity;3.29688705763713e-07!GO:0003713;transcription coactivator activity;3.33910898479311e-07!GO:0000245;spliceosome assembly;3.35244353678781e-07!GO:0006084;acetyl-CoA metabolic process;3.40607415486293e-07!GO:0006752;group transfer coenzyme metabolic process;3.40607415486293e-07!GO:0016740;transferase activity;3.5485323582415e-07!GO:0009117;nucleotide metabolic process;3.84042466113406e-07!GO:0051246;regulation of protein metabolic process;4.00993217403321e-07!GO:0045259;proton-transporting ATP synthase complex;4.49316246428624e-07!GO:0051168;nuclear export;5.43771413338443e-07!GO:0030120;vesicle coat;6.28252112451162e-07!GO:0030662;coated vesicle membrane;6.28252112451162e-07!GO:0008094;DNA-dependent ATPase activity;6.60615449183772e-07!GO:0006350;transcription;6.6067574182718e-07!GO:0006302;double-strand break repair;7.1804992001454e-07!GO:0007059;chromosome segregation;7.2179026202191e-07!GO:0009109;coenzyme catabolic process;7.3005007503974e-07!GO:0005773;vacuole;8.01211522905338e-07!GO:0000151;ubiquitin ligase complex;8.20984476512118e-07!GO:0043623;cellular protein complex assembly;1.06424420289329e-06!GO:0005793;ER-Golgi intermediate compartment;1.10112079405022e-06!GO:0006310;DNA recombination;1.17065235715319e-06!GO:0048475;coated membrane;1.31299790291282e-06!GO:0030117;membrane coat;1.31299790291282e-06!GO:0000323;lytic vacuole;1.36379092906555e-06!GO:0005764;lysosome;1.36379092906555e-06!GO:0005667;transcription factor complex;1.37216073966669e-06!GO:0016363;nuclear matrix;1.42992894029621e-06!GO:0007005;mitochondrion organization and biogenesis;1.46134110043034e-06!GO:0006793;phosphorus metabolic process;1.56876014706765e-06!GO:0006796;phosphate metabolic process;1.56876014706765e-06!GO:0003899;DNA-directed RNA polymerase activity;1.94542961471379e-06!GO:0051187;cofactor catabolic process;1.96829425196304e-06!GO:0042981;regulation of apoptosis;2.46624688086075e-06!GO:0005768;endosome;2.95986721443995e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;2.99792442393994e-06!GO:0043067;regulation of programmed cell death;3.64388646733081e-06!GO:0006613;cotranslational protein targeting to membrane;3.94751104681707e-06!GO:0006888;ER to Golgi vesicle-mediated transport;4.00770977199058e-06!GO:0006401;RNA catabolic process;4.35496388676568e-06!GO:0010468;regulation of gene expression;4.35496388676568e-06!GO:0050789;regulation of biological process;4.52439337539028e-06!GO:0016563;transcription activator activity;4.74261986364063e-06!GO:0003690;double-stranded DNA binding;4.94154342804837e-06!GO:0051427;hormone receptor binding;5.0058347368878e-06!GO:0003677;DNA binding;5.24264911790903e-06!GO:0005762;mitochondrial large ribosomal subunit;6.46207315955482e-06!GO:0000315;organellar large ribosomal subunit;6.46207315955482e-06!GO:0000776;kinetochore;7.1835664120287e-06!GO:0007088;regulation of mitosis;7.49486823231001e-06!GO:0031324;negative regulation of cellular metabolic process;8.22252518988997e-06!GO:0016853;isomerase activity;1.08094906969879e-05!GO:0035257;nuclear hormone receptor binding;1.08644181266992e-05!GO:0016491;oxidoreductase activity;1.14688269158857e-05!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.16603769421812e-05!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.41449701626238e-05!GO:0003724;RNA helicase activity;1.61808342431911e-05!GO:0016564;transcription repressor activity;1.94022467630554e-05!GO:0006612;protein targeting to membrane;2.02964189456991e-05!GO:0016741;transferase activity, transferring one-carbon groups;2.09051316028112e-05!GO:0004518;nuclease activity;2.19287584224348e-05!GO:0000786;nucleosome;2.41075439469189e-05!GO:0043021;ribonucleoprotein binding;3.07871215727991e-05!GO:0008168;methyltransferase activity;3.19904031875423e-05!GO:0008033;tRNA processing;3.28598049157881e-05!GO:0009165;nucleotide biosynthetic process;3.83150701257068e-05!GO:0044452;nucleolar part;3.9635935085097e-05!GO:0006357;regulation of transcription from RNA polymerase II promoter;4.24883225881467e-05!GO:0048523;negative regulation of cellular process;4.28596091633286e-05!GO:0003729;mRNA binding;5.20592675447323e-05!GO:0032774;RNA biosynthetic process;5.42713352340494e-05!GO:0045786;negative regulation of progression through cell cycle;5.54502521240732e-05!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;5.80570484007123e-05!GO:0016310;phosphorylation;5.82782208215708e-05!GO:0007093;mitotic cell cycle checkpoint;5.87898877392073e-05!GO:0006950;response to stress;5.90239989887106e-05!GO:0004527;exonuclease activity;6.28703717407478e-05!GO:0003684;damaged DNA binding;7.04050380764129e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;7.66481816311758e-05!GO:0006351;transcription, DNA-dependent;7.79916906121822e-05!GO:0003678;DNA helicase activity;7.80320838207013e-05!GO:0000059;protein import into nucleus, docking;8.0619972619336e-05!GO:0003682;chromatin binding;8.80191670121862e-05!GO:0000314;organellar small ribosomal subunit;0.000100153761344892!GO:0005763;mitochondrial small ribosomal subunit;0.000100153761344892!GO:0006091;generation of precursor metabolites and energy;0.000109354785178414!GO:0006405;RNA export from nucleus;0.000111997510130774!GO:0005788;endoplasmic reticulum lumen;0.000113763629542322!GO:0030880;RNA polymerase complex;0.000123181309872309!GO:0005798;Golgi-associated vesicle;0.000127318181081904!GO:0032508;DNA duplex unwinding;0.000129656347308533!GO:0032392;DNA geometric change;0.000129656347308533!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.000133361669853082!GO:0006414;translational elongation;0.000133822398829476!GO:0016859;cis-trans isomerase activity;0.000141044214064808!GO:0000228;nuclear chromosome;0.00014229958061069!GO:0008654;phospholipid biosynthetic process;0.00014551160597931!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000147740393063162!GO:0009892;negative regulation of metabolic process;0.000150066149883576!GO:0006383;transcription from RNA polymerase III promoter;0.000152874634679831!GO:0005885;Arp2/3 protein complex;0.000153853469202635!GO:0051052;regulation of DNA metabolic process;0.000162099284407893!GO:0015992;proton transport;0.000172418566263354!GO:0031988;membrane-bound vesicle;0.000173015083641316!GO:0006818;hydrogen transport;0.000179470867173583!GO:0043681;protein import into mitochondrion;0.000182385207446096!GO:0016481;negative regulation of transcription;0.000183099831756743!GO:0006268;DNA unwinding during replication;0.000228999533085811!GO:0007052;mitotic spindle organization and biogenesis;0.000256164603911849!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.000259934594538278!GO:0015399;primary active transmembrane transporter activity;0.000259934594538278!GO:0046489;phosphoinositide biosynthetic process;0.000269824407703171!GO:0006402;mRNA catabolic process;0.000269890264953214!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.000271474707258838!GO:0000428;DNA-directed RNA polymerase complex;0.000271474707258838!GO:0008186;RNA-dependent ATPase activity;0.000284913107910465!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.000285200980310092!GO:0016772;transferase activity, transferring phosphorus-containing groups;0.000311601916091311!GO:0016023;cytoplasmic membrane-bound vesicle;0.00032444647369211!GO:0045454;cell redox homeostasis;0.000327428621734289!GO:0000082;G1/S transition of mitotic cell cycle;0.000334328940077479!GO:0043069;negative regulation of programmed cell death;0.000350691345704041!GO:0019752;carboxylic acid metabolic process;0.000352053891799734!GO:0043596;nuclear replication fork;0.000354366353341682!GO:0006082;organic acid metabolic process;0.000363762582649529!GO:0006626;protein targeting to mitochondrion;0.000377400783757299!GO:0065009;regulation of a molecular function;0.00039542426070162!GO:0030867;rough endoplasmic reticulum membrane;0.000396280280364347!GO:0051252;regulation of RNA metabolic process;0.000422980245339237!GO:0043066;negative regulation of apoptosis;0.000426424957233833!GO:0045449;regulation of transcription;0.000449507633713994!GO:0044440;endosomal part;0.000470614748738338!GO:0010008;endosome membrane;0.000470614748738338!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000476357757162339!GO:0048519;negative regulation of biological process;0.000477197172735082!GO:0015980;energy derivation by oxidation of organic compounds;0.00047803334086843!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000486517302085988!GO:0031982;vesicle;0.000499363573344221!GO:0016281;eukaryotic translation initiation factor 4F complex;0.000527825203768946!GO:0005741;mitochondrial outer membrane;0.000561949461151029!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000574931661985617!GO:0031072;heat shock protein binding;0.000574931661985617!GO:0031968;organelle outer membrane;0.00058069167220121!GO:0031124;mRNA 3'-end processing;0.000631886808050061!GO:0016251;general RNA polymerase II transcription factor activity;0.000671274415107021!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000690469261936563!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000690469261936563!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000690469261936563!GO:0030384;phosphoinositide metabolic process;0.000715862433598223!GO:0046474;glycerophospholipid biosynthetic process;0.000783534972041333!GO:0004004;ATP-dependent RNA helicase activity;0.000820072789576278!GO:0019867;outer membrane;0.000820072789576278!GO:0005770;late endosome;0.000862589489825457!GO:0006916;anti-apoptosis;0.000868191961882463!GO:0048500;signal recognition particle;0.000888759644617738!GO:0045045;secretory pathway;0.000926537371677806!GO:0006611;protein export from nucleus;0.0010105943971027!GO:0000922;spindle pole;0.0010468750947069!GO:0005769;early endosome;0.00109472263647693!GO:0007006;mitochondrial membrane organization and biogenesis;0.00114503990223393!GO:0003702;RNA polymerase II transcription factor activity;0.00114899848570021!GO:0030658;transport vesicle membrane;0.00117387031323073!GO:0005684;U2-dependent spliceosome;0.0012280329520193!GO:0031410;cytoplasmic vesicle;0.00123766386872458!GO:0006352;transcription initiation;0.00124811471271052!GO:0006270;DNA replication initiation;0.00124811471271052!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00127706864401863!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00127706864401863!GO:0032940;secretion by cell;0.00131792540774181!GO:0008312;7S RNA binding;0.00132837835527237!GO:0051920;peroxiredoxin activity;0.00133114087253304!GO:0043601;nuclear replisome;0.00134792899363562!GO:0030894;replisome;0.00134792899363562!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00135305894530854!GO:0000819;sister chromatid segregation;0.00137071377532722!GO:0006839;mitochondrial transport;0.0014354307488655!GO:0005876;spindle microtubule;0.00155704047814234!GO:0019899;enzyme binding;0.00157291513064507!GO:0042393;histone binding;0.00157291513064507!GO:0046483;heterocycle metabolic process;0.00160948720878484!GO:0003924;GTPase activity;0.00161173905875025!GO:0033367;protein localization in mast cell secretory granule;0.00161173905875025!GO:0033365;protein localization in organelle;0.00161173905875025!GO:0033371;T cell secretory granule organization and biogenesis;0.00161173905875025!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.00161173905875025!GO:0033375;protease localization in T cell secretory granule;0.00161173905875025!GO:0042629;mast cell granule;0.00161173905875025!GO:0033377;maintenance of protein localization in T cell secretory granule;0.00161173905875025!GO:0033364;mast cell secretory granule organization and biogenesis;0.00161173905875025!GO:0033380;granzyme B localization in T cell secretory granule;0.00161173905875025!GO:0033379;maintenance of protease localization in T cell secretory granule;0.00161173905875025!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.00161173905875025!GO:0033368;protease localization in mast cell secretory granule;0.00161173905875025!GO:0033366;protein localization in secretory granule;0.00161173905875025!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.00161173905875025!GO:0033374;protein localization in T cell secretory granule;0.00161173905875025!GO:0005048;signal sequence binding;0.00173963818209554!GO:0030663;COPI coated vesicle membrane;0.00174013969720921!GO:0030126;COPI vesicle coat;0.00174013969720921!GO:0009112;nucleobase metabolic process;0.00177557489880662!GO:0043492;ATPase activity, coupled to movement of substances;0.00179724256693423!GO:0000725;recombinational repair;0.00181710032441397!GO:0000724;double-strand break repair via homologous recombination;0.00181710032441397!GO:0000070;mitotic sister chromatid segregation;0.00183324312438069!GO:0005525;GTP binding;0.00190574048118001!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00195802055802331!GO:0045047;protein targeting to ER;0.00195802055802331!GO:0044431;Golgi apparatus part;0.00202019060776338!GO:0006284;base-excision repair;0.00203639973414573!GO:0019843;rRNA binding;0.00205133180639258!GO:0000910;cytokinesis;0.002125616520216!GO:0031252;leading edge;0.00219428155477183!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00221726037766004!GO:0003714;transcription corepressor activity;0.00223884792672679!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00230409470125369!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00231593488690532!GO:0030660;Golgi-associated vesicle membrane;0.00236195220030482!GO:0000792;heterochromatin;0.0024318240395424!GO:0005758;mitochondrial intermembrane space;0.00246336888044176!GO:0003711;transcription elongation regulator activity;0.00255026077023414!GO:0000152;nuclear ubiquitin ligase complex;0.00259064858813591!GO:0031123;RNA 3'-end processing;0.00270546284226642!GO:0000049;tRNA binding;0.00273484263421586!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00276461783098668!GO:0006506;GPI anchor biosynthetic process;0.00284115830255191!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.00286381970118902!GO:0006417;regulation of translation;0.00288620356983677!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00291441645282896!GO:0006650;glycerophospholipid metabolic process;0.00309079894642461!GO:0044454;nuclear chromosome part;0.00311873998853187!GO:0051087;chaperone binding;0.00311873998853187!GO:0022890;inorganic cation transmembrane transporter activity;0.00314497529501036!GO:0005774;vacuolar membrane;0.00323129574874084!GO:0000178;exosome (RNase complex);0.00328311356071758!GO:0031570;DNA integrity checkpoint;0.00333909099688561!GO:0050662;coenzyme binding;0.00336880290951929!GO:0043284;biopolymer biosynthetic process;0.00339708069732394!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;0.00367611714774611!GO:0008408;3'-5' exonuclease activity;0.00371734840216384!GO:0006355;regulation of transcription, DNA-dependent;0.00378844424257951!GO:0006595;polyamine metabolic process;0.003793192965802!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.00389826187541899!GO:0032200;telomere organization and biogenesis;0.00412368647734602!GO:0000723;telomere maintenance;0.00412368647734602!GO:0006505;GPI anchor metabolic process;0.00421243185640836!GO:0006338;chromatin remodeling;0.0042533132809368!GO:0006733;oxidoreduction coenzyme metabolic process;0.00433732688574261!GO:0065007;biological regulation;0.00434664625352609!GO:0009451;RNA modification;0.0043528485525378!GO:0046467;membrane lipid biosynthetic process;0.00445472703583168!GO:0008276;protein methyltransferase activity;0.00445472703583168!GO:0051539;4 iron, 4 sulfur cluster binding;0.004580806272232!GO:0006767;water-soluble vitamin metabolic process;0.00467169083679832!GO:0035258;steroid hormone receptor binding;0.00483983497272947!GO:0006891;intra-Golgi vesicle-mediated transport;0.00483983497272947!GO:0000726;non-recombinational repair;0.00483983497272947!GO:0008632;apoptotic program;0.00483983497272947!GO:0006497;protein amino acid lipidation;0.00484383641222549!GO:0000339;RNA cap binding;0.00494417018234776!GO:0008610;lipid biosynthetic process;0.00499289490047441!GO:0000096;sulfur amino acid metabolic process;0.00504214091760588!GO:0006520;amino acid metabolic process;0.00510232236927202!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00515367683053367!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.00521784324991766!GO:0016272;prefoldin complex;0.00525610633214036!GO:0030118;clathrin coat;0.00526264455158299!GO:0031326;regulation of cellular biosynthetic process;0.00529157592269881!GO:0044262;cellular carbohydrate metabolic process;0.00549540558585811!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00551966621855174!GO:0043488;regulation of mRNA stability;0.00555809501052274!GO:0043487;regulation of RNA stability;0.00555809501052274!GO:0008047;enzyme activator activity;0.00558168508605908!GO:0030521;androgen receptor signaling pathway;0.00560396140176366!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00562051492920112!GO:0030176;integral to endoplasmic reticulum membrane;0.00566894388528723!GO:0006378;mRNA polyadenylation;0.00608518948345129!GO:0043414;biopolymer methylation;0.00608551070825125!GO:0006406;mRNA export from nucleus;0.00611691786556527!GO:0031970;organelle envelope lumen;0.00612516461323612!GO:0006144;purine base metabolic process;0.00614058672418914!GO:0006289;nucleotide-excision repair;0.00619281457461363!GO:0003887;DNA-directed DNA polymerase activity;0.0063520056785!GO:0032259;methylation;0.00644203520930704!GO:0046966;thyroid hormone receptor binding;0.0064610290874212!GO:0042802;identical protein binding;0.00646633515513542!GO:0007017;microtubule-based process;0.00654840036024788!GO:0005669;transcription factor TFIID complex;0.00656900751133487!GO:0007021;tubulin folding;0.00663311107569336!GO:0000139;Golgi membrane;0.00669771521355395!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.00677083776422775!GO:0030137;COPI-coated vesicle;0.00678202077705972!GO:0005637;nuclear inner membrane;0.00679598981361933!GO:0006376;mRNA splice site selection;0.0068017431947332!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0068017431947332!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00700949134116086!GO:0005765;lysosomal membrane;0.00706195242754683!GO:0051540;metal cluster binding;0.00710169256268129!GO:0051536;iron-sulfur cluster binding;0.00710169256268129!GO:0047485;protein N-terminus binding;0.00729619061392716!GO:0051053;negative regulation of DNA metabolic process;0.00729619061392716!GO:0044437;vacuolar part;0.00742675616638892!GO:0005791;rough endoplasmic reticulum;0.0074370901365744!GO:0008139;nuclear localization sequence binding;0.00762399388786426!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00762399388786426!GO:0046983;protein dimerization activity;0.00762399388786426!GO:0033116;ER-Golgi intermediate compartment membrane;0.00762399388786426!GO:0032603;fractalkine production;0.00762399388786426!GO:0050725;positive regulation of interleukin-1 beta biosynthetic process;0.00762399388786426!GO:0050752;regulation of fractalkine biosynthetic process;0.00762399388786426!GO:0045362;positive regulation of interleukin-1 biosynthetic process;0.00762399388786426!GO:0050754;positive regulation of fractalkine biosynthetic process;0.00762399388786426!GO:0001774;microglial cell activation;0.00762399388786426!GO:0050756;fractalkine metabolic process;0.00762399388786426!GO:0005766;primary lysosome;0.00762399388786426!GO:0050751;fractalkine biosynthetic process;0.00762399388786426!GO:0042222;interleukin-1 biosynthetic process;0.00762399388786426!GO:0050722;regulation of interleukin-1 beta biosynthetic process;0.00762399388786426!GO:0045360;regulation of interleukin-1 biosynthetic process;0.00762399388786426!GO:0042582;azurophil granule;0.00762399388786426!GO:0050720;interleukin-1 beta biosynthetic process;0.00762399388786426!GO:0051789;response to protein stimulus;0.00766360346198269!GO:0006986;response to unfolded protein;0.00766360346198269!GO:0005874;microtubule;0.00771585872670601!GO:0043065;positive regulation of apoptosis;0.00787627734225264!GO:0051287;NAD binding;0.00787627734225264!GO:0032984;macromolecular complex disassembly;0.00792380855889873!GO:0042158;lipoprotein biosynthetic process;0.00797468831107684!GO:0004532;exoribonuclease activity;0.00807055647461352!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.00807055647461352!GO:0016584;nucleosome positioning;0.00826656400025198!GO:0031577;spindle checkpoint;0.00828724507560008!GO:0005832;chaperonin-containing T-complex;0.00831704601842744!GO:0009124;nucleoside monophosphate biosynthetic process;0.00831737251243469!GO:0009123;nucleoside monophosphate metabolic process;0.00831737251243469!GO:0004540;ribonuclease activity;0.00837129923461307!GO:0050790;regulation of catalytic activity;0.00837129923461307!GO:0043022;ribosome binding;0.00842343439996262!GO:0003746;translation elongation factor activity;0.0086830422493967!GO:0009116;nucleoside metabolic process;0.00877361866084967!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00880301366386296!GO:0015002;heme-copper terminal oxidase activity;0.00880301366386296!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00880301366386296!GO:0004129;cytochrome-c oxidase activity;0.00880301366386296!GO:0015631;tubulin binding;0.00931069705204891!GO:0004003;ATP-dependent DNA helicase activity;0.00935519465560991!GO:0000118;histone deacetylase complex;0.00942606993938291!GO:0004177;aminopeptidase activity;0.00952706369475797!GO:0048522;positive regulation of cellular process;0.00959109080290437!GO:0016197;endosome transport;0.00966006739036908!GO:0004674;protein serine/threonine kinase activity;0.00976359511035208!GO:0007034;vacuolar transport;0.00992294862867122!GO:0043068;positive regulation of programmed cell death;0.0101268689932166!GO:0016791;phosphoric monoester hydrolase activity;0.0101579218944954!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0103969846793926!GO:0016018;cyclosporin A binding;0.0104438474855028!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0104649854680246!GO:0007040;lysosome organization and biogenesis;0.0110497285006083!GO:0016788;hydrolase activity, acting on ester bonds;0.0111160498355497!GO:0030518;steroid hormone receptor signaling pathway;0.0113379227022319!GO:0016279;protein-lysine N-methyltransferase activity;0.0113379227022319!GO:0018024;histone-lysine N-methyltransferase activity;0.0113379227022319!GO:0016278;lysine N-methyltransferase activity;0.0113379227022319!GO:0032039;integrator complex;0.0113667285320612!GO:0022411;cellular component disassembly;0.0115097057819615!GO:0006275;regulation of DNA replication;0.0115681074795402!GO:0042770;DNA damage response, signal transduction;0.0117112536692806!GO:0000077;DNA damage checkpoint;0.0119554783895757!GO:0000790;nuclear chromatin;0.0119993385719653!GO:0004576;oligosaccharyl transferase activity;0.0122953375038427!GO:0046112;nucleobase biosynthetic process;0.0122953375038427!GO:0048471;perinuclear region of cytoplasm;0.0124310942500115!GO:0005905;coated pit;0.0126643887851721!GO:0008097;5S rRNA binding;0.0127596008817728!GO:0006007;glucose catabolic process;0.0131074455590711!GO:0000781;chromosome, telomeric region;0.0131688079945259!GO:0030119;AP-type membrane coat adaptor complex;0.0131837792826375!GO:0009889;regulation of biosynthetic process;0.0137735921053685!GO:0043241;protein complex disassembly;0.0137735921053685!GO:0016311;dephosphorylation;0.014296755502952!GO:0042054;histone methyltransferase activity;0.0143435827746077!GO:0008250;oligosaccharyl transferase complex;0.0144232842132519!GO:0032561;guanyl ribonucleotide binding;0.0147449042952335!GO:0019001;guanyl nucleotide binding;0.0147449042952335!GO:0030041;actin filament polymerization;0.0148800331965677!GO:0007050;cell cycle arrest;0.015223274275849!GO:0006220;pyrimidine nucleotide metabolic process;0.0157032654080873!GO:0030125;clathrin vesicle coat;0.015775814857181!GO:0030665;clathrin coated vesicle membrane;0.015775814857181!GO:0008144;drug binding;0.015775814857181!GO:0005869;dynactin complex;0.016306678299568!GO:0006730;one-carbon compound metabolic process;0.016306678299568!GO:0005658;alpha DNA polymerase:primase complex;0.016475979701849!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.0168875469252836!GO:0008234;cysteine-type peptidase activity;0.0170934438938661!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0173799455647279!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0183817133409351!GO:0006509;membrane protein ectodomain proteolysis;0.018443644659433!GO:0033619;membrane protein proteolysis;0.018443644659433!GO:0030132;clathrin coat of coated pit;0.01845050322599!GO:0009161;ribonucleoside monophosphate metabolic process;0.0185672793657148!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.0185672793657148!GO:0002084;protein depalmitoylation;0.0185759755923758!GO:0006607;NLS-bearing substrate import into nucleus;0.0189390376841799!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0196371941213783!GO:0006672;ceramide metabolic process;0.0198543107254845!GO:0030131;clathrin adaptor complex;0.0198647731147158!GO:0006596;polyamine biosynthetic process;0.0199997996335624!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0211051593107536!GO:0051098;regulation of binding;0.0211665208517176!GO:0000287;magnesium ion binding;0.0216292681111982!GO:0051320;S phase;0.0216384289147432!GO:0005663;DNA replication factor C complex;0.0216384289147432!GO:0000086;G2/M transition of mitotic cell cycle;0.0216450939358093!GO:0008180;signalosome;0.0217329568371362!GO:0008538;proteasome activator activity;0.0220312805023298!GO:0007094;mitotic cell cycle spindle assembly checkpoint;0.022047048678824!GO:0030508;thiol-disulfide exchange intermediate activity;0.0220776914321697!GO:0003923;GPI-anchor transamidase activity;0.0220873040108408!GO:0016255;attachment of GPI anchor to protein;0.0220873040108408!GO:0042765;GPI-anchor transamidase complex;0.0220873040108408!GO:0000209;protein polyubiquitination;0.0226025016834198!GO:0006769;nicotinamide metabolic process;0.0227162449119085!GO:0044450;microtubule organizing center part;0.0228288650520721!GO:0003857;3-hydroxyacyl-CoA dehydrogenase activity;0.0232871544894353!GO:0008536;Ran GTPase binding;0.023397023442633!GO:0031371;ubiquitin conjugating enzyme complex;0.0236311103460488!GO:0005853;eukaryotic translation elongation factor 1 complex;0.0236311103460488!GO:0030433;ER-associated protein catabolic process;0.0236747911086951!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0236747911086951!GO:0005680;anaphase-promoting complex;0.0240641565323405!GO:0004520;endodeoxyribonuclease activity;0.0241210525906285!GO:0019206;nucleoside kinase activity;0.0242581280638879!GO:0018196;peptidyl-asparagine modification;0.0242581280638879!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0242581280638879!GO:0007033;vacuole organization and biogenesis;0.0246326691756127!GO:0043189;H4/H2A histone acetyltransferase complex;0.0252147395657178!GO:0004523;ribonuclease H activity;0.0253069940359191!GO:0007010;cytoskeleton organization and biogenesis;0.0254474890956234!GO:0035267;NuA4 histone acetyltransferase complex;0.0255727397546403!GO:0043524;negative regulation of neuron apoptosis;0.0258398946834807!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0258818448531433!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0262196825073122!GO:0045892;negative regulation of transcription, DNA-dependent;0.0262421211305734!GO:0030134;ER to Golgi transport vesicle;0.0262528568803306!GO:0046822;regulation of nucleocytoplasmic transport;0.0263518063382876!GO:0030133;transport vesicle;0.0263518063382876!GO:0046365;monosaccharide catabolic process;0.0264946239657011!GO:0016569;covalent chromatin modification;0.027129130013426!GO:0006301;postreplication repair;0.0272382171186905!GO:0043624;cellular protein complex disassembly;0.0276042985084551!GO:0048487;beta-tubulin binding;0.0276169031893228!GO:0000793;condensed chromosome;0.0281033716298677!GO:0005784;translocon complex;0.0281749794002854!GO:0004261;cathepsin G activity;0.0283907052549725!GO:0050681;androgen receptor binding;0.0283907052549725!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0286575617957104!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0287418191176261!GO:0010257;NADH dehydrogenase complex assembly;0.0287418191176261!GO:0033108;mitochondrial respiratory chain complex assembly;0.0287418191176261!GO:0043631;RNA polyadenylation;0.0288469929717512!GO:0007243;protein kinase cascade;0.029296696676765!GO:0006379;mRNA cleavage;0.0303383874021537!GO:0031647;regulation of protein stability;0.0304173981392998!GO:0005777;peroxisome;0.0306827651245562!GO:0042579;microbody;0.0306827651245562!GO:0006303;double-strand break repair via nonhomologous end joining;0.0310620537116606!GO:0008156;negative regulation of DNA replication;0.0310745154398678!GO:0009303;rRNA transcription;0.031162042431242!GO:0016180;snRNA processing;0.0315214525180157!GO:0016073;snRNA metabolic process;0.0315214525180157!GO:0030127;COPII vesicle coat;0.0317620646681762!GO:0012507;ER to Golgi transport vesicle membrane;0.0317620646681762!GO:0006266;DNA ligation;0.033109296392753!GO:0008637;apoptotic mitochondrial changes;0.0333970868759622!GO:0000175;3'-5'-exoribonuclease activity;0.0340116893264827!GO:0003756;protein disulfide isomerase activity;0.0342728895972884!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0342728895972884!GO:0006740;NADPH regeneration;0.0342728895972884!GO:0006098;pentose-phosphate shunt;0.0342728895972884!GO:0007004;telomere maintenance via telomerase;0.0343973092687813!GO:0001726;ruffle;0.0346932698741869!GO:0000097;sulfur amino acid biosynthetic process;0.0351487906195923!GO:0006400;tRNA modification;0.0351487906195923!GO:0006917;induction of apoptosis;0.0351973558932448!GO:0005996;monosaccharide metabolic process;0.0352622413951302!GO:0007041;lysosomal transport;0.0354456046596707!GO:0046982;protein heterodimerization activity;0.0358216948205337!GO:0008022;protein C-terminus binding;0.0360986190142729!GO:0015036;disulfide oxidoreductase activity;0.0366440444856784!GO:0004721;phosphoprotein phosphatase activity;0.0368813771404977!GO:0030911;TPR domain binding;0.0375291207511996!GO:0046128;purine ribonucleoside metabolic process;0.038428951485803!GO:0042278;purine nucleoside metabolic process;0.038428951485803!GO:0019318;hexose metabolic process;0.0384306799309952!GO:0006643;membrane lipid metabolic process;0.0384481439952167!GO:0019320;hexose catabolic process;0.0384739951601108!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0387241104817576!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0387888852639299!GO:0045039;protein import into mitochondrial inner membrane;0.0387888852639299!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0388164557485813!GO:0004536;deoxyribonuclease activity;0.0392146240864133!GO:0040029;regulation of gene expression, epigenetic;0.0392146240864133!GO:0042026;protein refolding;0.0396048581642094!GO:0000123;histone acetyltransferase complex;0.0397212394948872!GO:0017166;vinculin binding;0.0399651276885494!GO:0046164;alcohol catabolic process;0.0401000715043629!GO:0019362;pyridine nucleotide metabolic process;0.0402064438143506!GO:0016860;intramolecular oxidoreductase activity;0.0406335831743845!GO:0006118;electron transport;0.0410833083912821!GO:0030130;clathrin coat of trans-Golgi network vesicle;0.0413031915080054!GO:0012510;trans-Golgi network transport vesicle membrane;0.0413031915080054!GO:0006779;porphyrin biosynthetic process;0.0419090306215404!GO:0033014;tetrapyrrole biosynthetic process;0.0419090306215404!GO:0048037;cofactor binding;0.0422563417273287!GO:0046519;sphingoid metabolic process;0.042583590781855!GO:0016044;membrane organization and biogenesis;0.0426414180741653!GO:0007096;regulation of exit from mitosis;0.0431567989833028!GO:0010458;exit from mitosis;0.0431567989833028!GO:0012502;induction of programmed cell death;0.0431935801629612!GO:0006516;glycoprotein catabolic process;0.0433401302972231!GO:0016126;sterol biosynthetic process;0.0436523255792791!GO:0044438;microbody part;0.0451248711706383!GO:0044439;peroxisomal part;0.0451248711706383!GO:0004448;isocitrate dehydrogenase activity;0.0461823920614218!GO:0006778;porphyrin metabolic process;0.0463894640762117!GO:0033013;tetrapyrrole metabolic process;0.0463894640762117!GO:0022415;viral reproductive process;0.0478106640127925!GO:0006458;'de novo' protein folding;0.0480219595045538!GO:0051084;'de novo' posttranslational protein folding;0.0480219595045538!GO:0045947;negative regulation of translational initiation;0.0480219595045538!GO:0022406;membrane docking;0.0487550351898604!GO:0048278;vesicle docking;0.0487550351898604!GO:0031902;late endosome membrane;0.0491009396845297!GO:0031625;ubiquitin protein ligase binding;0.0491465062219078!GO:0006278;RNA-dependent DNA replication;0.0492926010389974!GO:0008537;proteasome activator complex;0.0495720609166639 | |||
|sample_id=10399 | |sample_id=10399 | ||
|sample_note=machine failed, remainder reloaded, low amount | |sample_note=machine failed, remainder reloaded, low amount | ||
| Line 76: | Line 99: | ||
|sample_tissue=blood | |sample_tissue=blood | ||
|top_motifs=MYB:2.38571439444;E2F1..5:1.86080844836;RXR{A,B,G}_{NR1H2,PPAR}dimers:1.5648312351;NANOG:1.55821936592;YY1:1.53788240333;NFY{A,B,C}:1.09572575345;AIRE:1.04809112678;ELK1,4_GABP{A,B1}:0.995700785318;NRF1:0.973245020574;DMAP1_NCOR{1,2}_SMARC:0.928274899438;SPIB:0.877107536976;ELF1,2,4:0.859527105053;CUX2:0.828700651606;SPI1:0.791942261133;NR6A1:0.791543169858;NANOG{mouse}:0.764451563975;BREu{core}:0.734494765475;RFX2..5_RFXANK_RFXAP:0.714967003571;ARID5B:0.632415235825;NR5A1,2:0.626788966922;NFIL3:0.610075985397;POU5F1:0.580431810154;HOX{A6,A7,B6,B7}:0.55595338007;CRX:0.545761708337;ZNF143:0.543717900832;FOXP3:0.536690082239;ALX1:0.530183165123;TEF:0.529646837692;NKX2-2,8:0.492736599017;FOXA2:0.472844495134;ETS1,2:0.464402147477;STAT1,3:0.462274976216;GCM1,2:0.458979424661;PAX5:0.439882115539;PRRX1,2:0.435399119634;TOPORS:0.421526694651;HOX{A5,B5}:0.389870967921;CEBPA,B_DDIT3:0.369116754359;PITX1..3:0.361927113071;POU2F1..3:0.354928854252;PPARG:0.34944568227;NKX3-2:0.333902555846;PAX8:0.306466231127;MYOD1:0.25809147642;GATA6:0.245219885365;CDX1,2,4:0.232688304005;NKX2-1,4:0.230442369096;OCT4_SOX2{dimer}:0.227787006518;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.195795006568;HOX{A4,D4}:0.191359355161;RXRA_VDR{dimer}:0.185215630818;TFDP1:0.180915702512;GFI1:0.169815119707;HNF4A_NR2F1,2:0.163696392721;PBX1:0.115248167057;EN1,2:0.114084689047;KLF4:0.109712799056;POU1F1:0.100682181321;DBP:0.0914711520296;SRF:0.0903270133543;HAND1,2:0.0751527868093;PRDM1:0.0744141171184;RUNX1..3:0.0704077892641;HLF:0.0647614956572;PAX3,7:0.0639081747142;FOXN1:0.0532195222498;CREB1:0.0164598621757;GATA4:0.00887728104028;NFE2L1:0.00118122898093;FOXD3:-0.0267850403779;HBP1_HMGB_SSRP1_UBTF:-0.0345397277577;HNF1A:-0.0436829323307;HES1:-0.0458525800612;ESR1:-0.0515949015521;bHLH_family:-0.0657431191523;RORA:-0.0658134370502;SOX{8,9,10}:-0.0708041899175;SREBF1,2:-0.0816588627571;NKX2-3_NKX2-5:-0.0860774232462;FOXP1:-0.10176023875;AR:-0.11410883221;IRF1,2:-0.124992840446;POU3F1..4:-0.127397663966;NKX3-1:-0.187541550108;NR1H4:-0.197783682064;TAL1_TCF{3,4,12}:-0.198985216951;IRF7:-0.224014180213;EP300:-0.231002381173;SOX17:-0.237722364014;MEF2{A,B,C,D}:-0.238847490811;MTF1:-0.240545411356;ZNF238:-0.250484327357;ZEB1:-0.258056280383;NFE2L2:-0.288689856554;MYBL2:-0.302145309465;LEF1_TCF7_TCF7L1,2:-0.327675601903;VSX1,2:-0.336682452292;IKZF2:-0.34048314813;TGIF1:-0.353134170141;ATF5_CREB3:-0.361720365069;FOXQ1:-0.366984162309;PAX2:-0.367809609764;HSF1,2:-0.371010420366;POU6F1:-0.371863045129;FOX{F1,F2,J1}:-0.382510199737;REST:-0.385685183681;SOX5:-0.389249608004;STAT5{A,B}:-0.390657097195;NFKB1_REL_RELA:-0.395965060397;ATF4:-0.409824992887;FOSL2:-0.419332100583;ZBTB16:-0.420122548872;ATF2:-0.420135336728;HIF1A:-0.431774994075;LMO2:-0.432053807533;ZNF423:-0.443327612715;AHR_ARNT_ARNT2:-0.447340920782;ESRRA:-0.453654568381;FOS_FOS{B,L1}_JUN{B,D}:-0.485917009431;TLX2:-0.501458372765;RFX1:-0.506856321973;ZFP161:-0.509308265492;NHLH1,2:-0.512982859611;NFE2:-0.519260492884;PDX1:-0.521708354282;EVI1:-0.536355085409;TFAP2{A,C}:-0.543555837237;ONECUT1,2:-0.551368667521;BACH2:-0.555527440254;HOXA9_MEIS1:-0.561577980598;SPZ1:-0.564288812318;T:-0.56480351638;LHX3,4:-0.575435906465;NKX6-1,2:-0.578903488918;MZF1:-0.596657781787;RBPJ:-0.608229964557;SNAI1..3:-0.630101954886;TBP:-0.634383843583;TBX4,5:-0.635783488861;ATF6:-0.636850678728;PAX6:-0.663878797442;XBP1:-0.672183754369;UFEwm:-0.675535618606;MYFfamily:-0.68455027183;TP53:-0.690925055885;MED-1{core}:-0.743168502117;MTE{core}:-0.753300121195;TFAP4:-0.762498284284;HMGA1,2:-0.769052058915;IKZF1:-0.785982125814;ZNF148:-0.788728151482;GTF2A1,2:-0.791549002759;RXR{A,B,G}:-0.792681322006;PAX4:-0.797917026843;HIC1:-0.807115229951;ZNF384:-0.824704457797;GZF1:-0.8513722144;FOX{I1,J2}:-0.856901886037;GTF2I:-0.874294966008;MAFB:-0.898597462327;ZIC1..3:-0.951432761538;ADNP_IRX_SIX_ZHX:-0.964214261232;XCPE1{core}:-0.970002732111;SOX2:-0.971691227922;TLX1..3_NFIC{dimer}:-0.998389786469;STAT2,4,6:-1.01331586195;FOXO1,3,4:-1.01374002047;NFIX:-1.0262425732;EBF1:-1.04815579736;TEAD1:-1.05973421437;RREB1:-1.07412945118;ZBTB6:-1.07438566472;EGR1..3:-1.0790299204;NR3C1:-1.12261058689;PAX1,9:-1.15496281054;HMX1:-1.15714604721;SP1:-1.15737573284;FOXM1:-1.16296821048;TFAP2B:-1.16818107781;ALX4:-1.21613799243;MAZ:-1.21679280002;CDC5L:-1.22236383027;TFCP2:-1.23973345613;GLI1..3:-1.30005525191;PATZ1:-1.30975713914;NFATC1..3:-1.32893636814;GFI1B:-1.38152271409;JUN:-1.39799317945;SMAD1..7,9:-1.40814535979;FOXL1:-1.42651316955;BPTF:-1.47709836406;FOX{D1,D2}:-1.52114341732 | |top_motifs=MYB:2.38571439444;E2F1..5:1.86080844836;RXR{A,B,G}_{NR1H2,PPAR}dimers:1.5648312351;NANOG:1.55821936592;YY1:1.53788240333;NFY{A,B,C}:1.09572575345;AIRE:1.04809112678;ELK1,4_GABP{A,B1}:0.995700785318;NRF1:0.973245020574;DMAP1_NCOR{1,2}_SMARC:0.928274899438;SPIB:0.877107536976;ELF1,2,4:0.859527105053;CUX2:0.828700651606;SPI1:0.791942261133;NR6A1:0.791543169858;NANOG{mouse}:0.764451563975;BREu{core}:0.734494765475;RFX2..5_RFXANK_RFXAP:0.714967003571;ARID5B:0.632415235825;NR5A1,2:0.626788966922;NFIL3:0.610075985397;POU5F1:0.580431810154;HOX{A6,A7,B6,B7}:0.55595338007;CRX:0.545761708337;ZNF143:0.543717900832;FOXP3:0.536690082239;ALX1:0.530183165123;TEF:0.529646837692;NKX2-2,8:0.492736599017;FOXA2:0.472844495134;ETS1,2:0.464402147477;STAT1,3:0.462274976216;GCM1,2:0.458979424661;PAX5:0.439882115539;PRRX1,2:0.435399119634;TOPORS:0.421526694651;HOX{A5,B5}:0.389870967921;CEBPA,B_DDIT3:0.369116754359;PITX1..3:0.361927113071;POU2F1..3:0.354928854252;PPARG:0.34944568227;NKX3-2:0.333902555846;PAX8:0.306466231127;MYOD1:0.25809147642;GATA6:0.245219885365;CDX1,2,4:0.232688304005;NKX2-1,4:0.230442369096;OCT4_SOX2{dimer}:0.227787006518;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.195795006568;HOX{A4,D4}:0.191359355161;RXRA_VDR{dimer}:0.185215630818;TFDP1:0.180915702512;GFI1:0.169815119707;HNF4A_NR2F1,2:0.163696392721;PBX1:0.115248167057;EN1,2:0.114084689047;KLF4:0.109712799056;POU1F1:0.100682181321;DBP:0.0914711520296;SRF:0.0903270133543;HAND1,2:0.0751527868093;PRDM1:0.0744141171184;RUNX1..3:0.0704077892641;HLF:0.0647614956572;PAX3,7:0.0639081747142;FOXN1:0.0532195222498;CREB1:0.0164598621757;GATA4:0.00887728104028;NFE2L1:0.00118122898093;FOXD3:-0.0267850403779;HBP1_HMGB_SSRP1_UBTF:-0.0345397277577;HNF1A:-0.0436829323307;HES1:-0.0458525800612;ESR1:-0.0515949015521;bHLH_family:-0.0657431191523;RORA:-0.0658134370502;SOX{8,9,10}:-0.0708041899175;SREBF1,2:-0.0816588627571;NKX2-3_NKX2-5:-0.0860774232462;FOXP1:-0.10176023875;AR:-0.11410883221;IRF1,2:-0.124992840446;POU3F1..4:-0.127397663966;NKX3-1:-0.187541550108;NR1H4:-0.197783682064;TAL1_TCF{3,4,12}:-0.198985216951;IRF7:-0.224014180213;EP300:-0.231002381173;SOX17:-0.237722364014;MEF2{A,B,C,D}:-0.238847490811;MTF1:-0.240545411356;ZNF238:-0.250484327357;ZEB1:-0.258056280383;NFE2L2:-0.288689856554;MYBL2:-0.302145309465;LEF1_TCF7_TCF7L1,2:-0.327675601903;VSX1,2:-0.336682452292;IKZF2:-0.34048314813;TGIF1:-0.353134170141;ATF5_CREB3:-0.361720365069;FOXQ1:-0.366984162309;PAX2:-0.367809609764;HSF1,2:-0.371010420366;POU6F1:-0.371863045129;FOX{F1,F2,J1}:-0.382510199737;REST:-0.385685183681;SOX5:-0.389249608004;STAT5{A,B}:-0.390657097195;NFKB1_REL_RELA:-0.395965060397;ATF4:-0.409824992887;FOSL2:-0.419332100583;ZBTB16:-0.420122548872;ATF2:-0.420135336728;HIF1A:-0.431774994075;LMO2:-0.432053807533;ZNF423:-0.443327612715;AHR_ARNT_ARNT2:-0.447340920782;ESRRA:-0.453654568381;FOS_FOS{B,L1}_JUN{B,D}:-0.485917009431;TLX2:-0.501458372765;RFX1:-0.506856321973;ZFP161:-0.509308265492;NHLH1,2:-0.512982859611;NFE2:-0.519260492884;PDX1:-0.521708354282;EVI1:-0.536355085409;TFAP2{A,C}:-0.543555837237;ONECUT1,2:-0.551368667521;BACH2:-0.555527440254;HOXA9_MEIS1:-0.561577980598;SPZ1:-0.564288812318;T:-0.56480351638;LHX3,4:-0.575435906465;NKX6-1,2:-0.578903488918;MZF1:-0.596657781787;RBPJ:-0.608229964557;SNAI1..3:-0.630101954886;TBP:-0.634383843583;TBX4,5:-0.635783488861;ATF6:-0.636850678728;PAX6:-0.663878797442;XBP1:-0.672183754369;UFEwm:-0.675535618606;MYFfamily:-0.68455027183;TP53:-0.690925055885;MED-1{core}:-0.743168502117;MTE{core}:-0.753300121195;TFAP4:-0.762498284284;HMGA1,2:-0.769052058915;IKZF1:-0.785982125814;ZNF148:-0.788728151482;GTF2A1,2:-0.791549002759;RXR{A,B,G}:-0.792681322006;PAX4:-0.797917026843;HIC1:-0.807115229951;ZNF384:-0.824704457797;GZF1:-0.8513722144;FOX{I1,J2}:-0.856901886037;GTF2I:-0.874294966008;MAFB:-0.898597462327;ZIC1..3:-0.951432761538;ADNP_IRX_SIX_ZHX:-0.964214261232;XCPE1{core}:-0.970002732111;SOX2:-0.971691227922;TLX1..3_NFIC{dimer}:-0.998389786469;STAT2,4,6:-1.01331586195;FOXO1,3,4:-1.01374002047;NFIX:-1.0262425732;EBF1:-1.04815579736;TEAD1:-1.05973421437;RREB1:-1.07412945118;ZBTB6:-1.07438566472;EGR1..3:-1.0790299204;NR3C1:-1.12261058689;PAX1,9:-1.15496281054;HMX1:-1.15714604721;SP1:-1.15737573284;FOXM1:-1.16296821048;TFAP2B:-1.16818107781;ALX4:-1.21613799243;MAZ:-1.21679280002;CDC5L:-1.22236383027;TFCP2:-1.23973345613;GLI1..3:-1.30005525191;PATZ1:-1.30975713914;NFATC1..3:-1.32893636814;GFI1B:-1.38152271409;JUN:-1.39799317945;SMAD1..7,9:-1.40814535979;FOXL1:-1.42651316955;BPTF:-1.47709836406;FOX{D1,D2}:-1.52114341732 | ||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10399-106A3;search_select_hide=table117:FF:10399-106A3 | |||
}} | }} | ||
Latest revision as of 13:59, 3 June 2020
| Name: | acute myeloid leukemia (FAB M5) cell line:THP-1 (fresh) |
|---|---|
| Species: | Human (Homo sapiens) |
| Library ID: | CNhs10722 |
| Sample type: | cell lines |
| Genomic View: | UCSC |
| RefEX: | Specific genes |
| CAGEd-oPOSSUM: | link |
| ZENBU report : | link |
| Additional information | ||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sample information
RNA information
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| CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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| Download raw sequence, BAM & CTSS | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs10722
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs10722
| Novel motif | Logo | P-value |
|---|---|---|
| 1 | 1 | 0.041 |
| 10 | 10 | 0.0156 |
| 100 | 100 | 0.158 |
| 101 | 101 | 0.264 |
| 102 | 102 | 0.803 |
| 103 | 103 | 0.719 |
| 104 | 104 | 0.697 |
| 105 | 105 | 0.781 |
| 106 | 106 | 0.0874 |
| 107 | 107 | 0.146 |
| 108 | 108 | 0.426 |
| 109 | 109 | 0.0228 |
| 11 | 11 | 0.122 |
| 110 | 110 | 0.251 |
| 111 | 111 | 0.477 |
| 112 | 112 | 0.65 |
| 113 | 113 | 0.152 |
| 114 | 114 | 0.223 |
| 115 | 115 | 0.359 |
| 116 | 116 | 0.626 |
| 117 | 117 | 0.0555 |
| 118 | 118 | 0.176 |
| 119 | 119 | 0.878 |
| 12 | 12 | 0.802 |
| 120 | 120 | 0.514 |
| 121 | 121 | 0.899 |
| 122 | 122 | 0.0751 |
| 123 | 123 | 0.953 |
| 124 | 124 | 0.227 |
| 125 | 125 | 0.485 |
| 126 | 126 | 0.533 |
| 127 | 127 | 0.0855 |
| 128 | 128 | 0.101 |
| 129 | 129 | 0.899 |
| 13 | 13 | 0.00104 |
| 130 | 130 | 0.516 |
| 131 | 131 | 0.00929 |
| 132 | 132 | 0.921 |
| 133 | 133 | 0.345 |
| 134 | 134 | 0.456 |
| 135 | 135 | 0.222 |
| 136 | 136 | 0.197 |
| 137 | 137 | 0.448 |
| 138 | 138 | 0.909 |
| 139 | 139 | 0.675 |
| 14 | 14 | 0.726 |
| 140 | 140 | 0.192 |
| 141 | 141 | 0.825 |
| 142 | 142 | 0.795 |
| 143 | 143 | 0.333 |
| 144 | 144 | 0.717 |
| 145 | 145 | 0.596 |
| 146 | 146 | 0.753 |
| 147 | 147 | 0.143 |
| 148 | 148 | 0.0258 |
| 149 | 149 | 0.188 |
| 15 | 15 | 0.251 |
| 150 | 150 | 0.533 |
| 151 | 151 | 0.484 |
| 152 | 152 | 0.0569 |
| 153 | 153 | 0.462 |
| 154 | 154 | 0.863 |
| 155 | 155 | 0.0714 |
| 156 | 156 | 0.791 |
| 157 | 157 | 0.595 |
| 158 | 158 | 0.431 |
| 159 | 159 | 0.505 |
| 16 | 16 | 0.747 |
| 160 | 160 | 0.765 |
| 161 | 161 | 0.111 |
| 162 | 162 | 0.538 |
| 163 | 163 | 0.561 |
| 164 | 164 | 0.473 |
| 165 | 165 | 0.0451 |
| 166 | 166 | 0.293 |
| 167 | 167 | 0.401 |
| 168 | 168 | 0.976 |
| 169 | 169 | 0.98 |
| 17 | 17 | 0.576 |
| 18 | 18 | 0.909 |
| 19 | 19 | 0.846 |
| 2 | 2 | 0.261 |
| 20 | 20 | 0.296 |
| 21 | 21 | 0.284 |
| 22 | 22 | 0.826 |
| 23 | 23 | 0.00888 |
| 24 | 24 | 0.0299 |
| 25 | 25 | 0.412 |
| 26 | 26 | 0.608 |
| 27 | 27 | 0.527 |
| 28 | 28 | 0.873 |
| 29 | 29 | 0.0141 |
| 3 | 3 | 0.0355 |
| 30 | 30 | 0.0849 |
| 31 | 31 | 0.487 |
| 32 | 32 | 0.102 |
| 33 | 33 | 0.36 |
| 34 | 34 | 0.534 |
| 35 | 35 | 0.494 |
| 36 | 36 | 0.0474 |
| 37 | 37 | 0.4 |
| 38 | 38 | 0.229 |
| 39 | 39 | 0.247 |
| 4 | 4 | 0.115 |
| 40 | 40 | 0.333 |
| 41 | 41 | 0.861 |
| 42 | 42 | 0.131 |
| 43 | 43 | 0.863 |
| 44 | 44 | 0.446 |
| 45 | 45 | 0.284 |
| 46 | 46 | 0.169 |
| 47 | 47 | 0.0746 |
| 48 | 48 | 0.0505 |
| 49 | 49 | 0.809 |
| 5 | 5 | 0.68 |
| 50 | 50 | 0.801 |
| 51 | 51 | 0.847 |
| 52 | 52 | 0.0977 |
| 53 | 53 | 0.395 |
| 54 | 54 | 0.504 |
| 55 | 55 | 0.564 |
| 56 | 56 | 0.771 |
| 57 | 57 | 0.239 |
| 58 | 58 | 0.24 |
| 59 | 59 | 0.752 |
| 6 | 6 | 0.559 |
| 60 | 60 | 0.293 |
| 61 | 61 | 0.0996 |
| 62 | 62 | 0.351 |
| 63 | 63 | 0.95 |
| 64 | 64 | 0.314 |
| 65 | 65 | 0.79 |
| 66 | 66 | 0.00684 |
| 67 | 67 | 0.376 |
| 68 | 68 | 0.171 |
| 69 | 69 | 0.361 |
| 7 | 7 | 0.174 |
| 70 | 70 | 0.261 |
| 71 | 71 | 0.0732 |
| 72 | 72 | 0.741 |
| 73 | 73 | 0.761 |
| 74 | 74 | 0.756 |
| 75 | 75 | 0.038 |
| 76 | 76 | 0.237 |
| 77 | 77 | 0.486 |
| 78 | 78 | 0.034 |
| 79 | 79 | 0.232 |
| 8 | 8 | 0.558 |
| 80 | 80 | 0.249 |
| 81 | 81 | 0.408 |
| 82 | 82 | 0.651 |
| 83 | 83 | 0.817 |
| 84 | 84 | 0.857 |
| 85 | 85 | 0.0248 |
| 86 | 86 | 0.967 |
| 87 | 87 | 0.0361 |
| 88 | 88 | 0.397 |
| 89 | 89 | 0.394 |
| 9 | 9 | 0.621 |
| 90 | 90 | 0.0681 |
| 91 | 91 | 0.18 |
| 92 | 92 | 0.0885 |
| 93 | 93 | 0.648 |
| 94 | 94 | 0.884 |
| 95 | 95 | 0.00392 |
| 96 | 96 | 0.635 |
| 97 | 97 | 0.556 |
| 98 | 98 | 0.546 |
| 99 | 99 | 0.439 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs10722
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0101370 THP-1 cell sample
FF:0101883 acute myeloid leukemia cell line sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000766 (myeloid leukocyte)
0000219 (motile cell)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0000255 (eukaryotic cell)
0000576 (monocyte)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
2531 (hematologic cancer)
14566 (disease of cellular proliferation)
0060083 (immune system cancer)
1240 (leukemia)
8692 (myeloid leukemia)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100737 (leukemia cell line sample)
0101370 (THP-1 cell sample)
0101035 (hematopoietic cell line sample)
0101883 (acute myeloid leukemia cell line sample)
0102332 (monocytic leukemia cell line sample)
0100740 (myeloid leukemia cell line sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)
